Using the NCEP/NCAR reanalysis data, the China rainfall data of the China Meteorological Administration, and the sea surface temperature (SST) data of NOAA from 1951-2000, the features of the anomalous longitudinal po...Using the NCEP/NCAR reanalysis data, the China rainfall data of the China Meteorological Administration, and the sea surface temperature (SST) data of NOAA from 1951-2000, the features of the anomalous longitudinal position of the subtropical high in the western Pacific (SHWP) in the pre-rainy season in South China and associated circulation and precipitation are studied. Furthermore, the relationship between SHWP and SST and the eastern Asian winter monsoon is also investigated. Associated with the anomalous longitudinal position of SHWP in the pre-rainy season in South China, the flow patterns in both the middle and lower latitudes are different. The circulation anomalies greatly influence the precipitation in the pre-rainy season in South China. When the SHWP is in a west position (WP), the South China quasi-stationary front is stronger with more abundant precipitation there. However, when the SHWP is in an east position (EP), a weaker front appears with a shortage of precipitation there. There exists a good relationship between the longitudinal position of SHWP and SST in the tropical region. A negative correlation can be found both in the central and eastern tropical Pacific and the Indian Ocean. This means that the higher (lower) SST there corresponds to a west (east) position of SHWP. This close relationship can be found even in the preceding autumn and winter. A positive correlation appears in the western and northern Pacific and large correlation coefficient values also occur in the preceding autumn and winter. A stronger eastern Asian winter monsoon will give rise to cooler SSTs in the Kuroshio and the South China Sea regions and it corresponds to negative SST anomaly (SSTA) in the central and eastern Pacific and positive SSTA in the western Pacific in winter and the following spring. The whole tropical SSTA pattern, that is, positive (negative) SSTA in the central and eastern Pacific and negative (positive) SSTA in the western Pacific, is favorable to the WP (EP) of SHWP.展开更多
Objective In this study, we evaluated the difference of progression-free survival （PFS） and overall survival （OS） between extensive-stage small-cell lung cancer （ES-SCLC） patients who acquired partial response ...Objective In this study, we evaluated the difference of progression-free survival （PFS） and overall survival （OS） between extensive-stage small-cell lung cancer （ES-SCLC） patients who acquired partial response （PR） or complete remission （CR） after two cycles of first-line chemotherapy with the etoposide plus cisplatin （EP） regimen and those who acquired PR or CR after four or six cycles. Methods A total of 106 eligible patients treated with the EP chemotherapy regimen for two to six cycles, at The General Hospital of Shenyang Military Region （China） between November 2004 and Way 2011, were enrolled in this study. RECIST version 1.1 was used for the evaluation of chemotherapy efficiency. We followed up all eligible patients every 4 weeks. All statistical data were analyzed by using SPSS 21.0 statistical package for Windows. Results After a median follow-up of 293 days （range, 62-1531 days）, all patients had died by the cutoff date. Fifty-one patients acquired PR or CR after two cycles of chemotherapy; the median PFS reached 6.0 months （95% CI, 5.1-6.9）, and the median OS was 10.5 months （95% CI, 8.6-12.4）. Twenty-eight patients acquired PR or CR after four or six cycles; the median PFS was 4.8 months （95% CI, 4.4-5.2）, and the median OS was 7.5 months （95% CI, 6.8-8.2）. Both PFS and OS showed a statistical difference between the two groups. Conclusion ES-SCLC patients who acquired PR or CR after two cycles of the EP regimen as first-line therapy had longer PFS and OS than those who acquired PR or CR after four or six cycles.展开更多
基金This work was supported by the National Key Basic Research and Development Project of China 2004CB18300the Key Knowledge Innovation Project of Chinese Academy of Sciences(Grand No.KZCX3-SW-226)the National Natural Science Foundation of China under Grant Nos.40135020 and 40325015.
文摘Using the NCEP/NCAR reanalysis data, the China rainfall data of the China Meteorological Administration, and the sea surface temperature (SST) data of NOAA from 1951-2000, the features of the anomalous longitudinal position of the subtropical high in the western Pacific (SHWP) in the pre-rainy season in South China and associated circulation and precipitation are studied. Furthermore, the relationship between SHWP and SST and the eastern Asian winter monsoon is also investigated. Associated with the anomalous longitudinal position of SHWP in the pre-rainy season in South China, the flow patterns in both the middle and lower latitudes are different. The circulation anomalies greatly influence the precipitation in the pre-rainy season in South China. When the SHWP is in a west position (WP), the South China quasi-stationary front is stronger with more abundant precipitation there. However, when the SHWP is in an east position (EP), a weaker front appears with a shortage of precipitation there. There exists a good relationship between the longitudinal position of SHWP and SST in the tropical region. A negative correlation can be found both in the central and eastern tropical Pacific and the Indian Ocean. This means that the higher (lower) SST there corresponds to a west (east) position of SHWP. This close relationship can be found even in the preceding autumn and winter. A positive correlation appears in the western and northern Pacific and large correlation coefficient values also occur in the preceding autumn and winter. A stronger eastern Asian winter monsoon will give rise to cooler SSTs in the Kuroshio and the South China Sea regions and it corresponds to negative SST anomaly (SSTA) in the central and eastern Pacific and positive SSTA in the western Pacific in winter and the following spring. The whole tropical SSTA pattern, that is, positive (negative) SSTA in the central and eastern Pacific and negative (positive) SSTA in the western Pacific, is favorable to the WP (EP) of SHWP.
基金Supported by grants from the National Research Key Project of the Twelfth Five-year Plan of the Republic of China(No.2012ZX09303016-002)the Science and Technology Key Programs of Liaoning Province(No.2012225019)
文摘Objective In this study, we evaluated the difference of progression-free survival （PFS） and overall survival （OS） between extensive-stage small-cell lung cancer （ES-SCLC） patients who acquired partial response （PR） or complete remission （CR） after two cycles of first-line chemotherapy with the etoposide plus cisplatin （EP） regimen and those who acquired PR or CR after four or six cycles. Methods A total of 106 eligible patients treated with the EP chemotherapy regimen for two to six cycles, at The General Hospital of Shenyang Military Region （China） between November 2004 and Way 2011, were enrolled in this study. RECIST version 1.1 was used for the evaluation of chemotherapy efficiency. We followed up all eligible patients every 4 weeks. All statistical data were analyzed by using SPSS 21.0 statistical package for Windows. Results After a median follow-up of 293 days （range, 62-1531 days）, all patients had died by the cutoff date. Fifty-one patients acquired PR or CR after two cycles of chemotherapy; the median PFS reached 6.0 months （95% CI, 5.1-6.9）, and the median OS was 10.5 months （95% CI, 8.6-12.4）. Twenty-eight patients acquired PR or CR after four or six cycles; the median PFS was 4.8 months （95% CI, 4.4-5.2）, and the median OS was 7.5 months （95% CI, 6.8-8.2）. Both PFS and OS showed a statistical difference between the two groups. Conclusion ES-SCLC patients who acquired PR or CR after two cycles of the EP regimen as first-line therapy had longer PFS and OS than those who acquired PR or CR after four or six cycles.
