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Surface Grafting of Phenolic Resole onto LDPE Films
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作者 Jue CHENG Yi ZHENG Wan Tai YANG 《Chinese Chemical Letters》 SCIE CAS CSCD 2006年第8期1133-1136,共4页
Low density polyethylene film surface-grafted phenolic resole was prepared by a sequential processes. Firstly, acrylic acid was grafted to the surface of low density polyethylene by photo-grafting. Secondly, the carbo... Low density polyethylene film surface-grafted phenolic resole was prepared by a sequential processes. Firstly, acrylic acid was grafted to the surface of low density polyethylene by photo-grafting. Secondly, the carboxylic groups in poly(acrylic acid) chains were transferred to sulfonic groups by the reaction of carboxylic groups with sulfanilic acid. Finally, a thin layer of phenolic resole was cured onto the surface of low density polyethylene. The grafting process was characterized by FTIR-ATR and gravimetric analysis. A possible model was proposed to interpret the experimental results. 展开更多
关键词 surface grafting low density polyethylene film sulfanilic acid phenolic resole.
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Glucose-sensitive Membrane with PBA-based Contraction-type Linear Polymer as Chemical Valves Prepared by Surface Grafting
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作者 Chun-Peng Zhang Si-Jia Gao +2 位作者 Ying Luo Lei Zou Yong-Jun Zhang 《Chinese Journal of Polymer Science》 SCIE EI CAS CSCD 2024年第8期1067-1076,共10页
Glucose-sensitive membrane has potential application in self-regulating insulin release.Phenylboronic acid(PBA)is a well-known glucose reporter.Unfortunately,most PBA-based glucose-sensitive materials are expansion-ty... Glucose-sensitive membrane has potential application in self-regulating insulin release.Phenylboronic acid(PBA)is a well-known glucose reporter.Unfortunately,most PBA-based glucose-sensitive materials are expansion-type,which are not suitable as chemical valves in membrane pores for self-regulating insulin release.According to a new glucose-sensitive mechanism,we synthesized PBA-based contraction-type glucose-sensitive liner polymer and microgels.Herein,a glucose-sensitive membrane was prepared by grafting PBA-based contraction-type glucose-sensitive linear polymer on the membrane surface.Through adjusting the chain length and chain density,the glucose-sensitivity of the membrane was optimized.The membrane can reversibly regulate insulin release at physiologically relevant glucose concentrations in simulates body fluids and fetal bovine serum.The membrane also has good stability,anti-fouling and biocom patibility.It has potential application in selfregulating insulin release. 展开更多
关键词 Phenylboronic acid Glucose-sensitive MEMBRANE surface grafting Insulin
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Surface Modification of Polyvinylidene Fluoride (PVDF) Membranes by Low-Temperature Plasma with Grafting Styrene 被引量:3
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作者 陈剑 李继定 陈翠仙 《Plasma Science and Technology》 SCIE EI CAS CSCD 2009年第1期42-47,共6页
In order to control the surface pore sizes of polyvinylidene fluoride membranes and their distribution, low temperature plasma-induced grafting modifications of PVDF were studied to prepare hydrophobe membranes. By ar... In order to control the surface pore sizes of polyvinylidene fluoride membranes and their distribution, low temperature plasma-induced grafting modifications of PVDF were studied to prepare hydrophobe membranes. By argon (Ar) treating and subsequent grafting reaction, a hydrophobe monomer, styrene, was introduced into the PVDF membrane. Fourier transform infrared attenuated total reflection (FTIR-ATR) was utilized to characterize the chemical and physical changes in the Ar plasma modified membrane. The surface modifications of PVDF membranes were investigated by using scanning electron microscopy (SEM), atomic force microscopy (AFM) and differential scanning calorimeter (DSC). The water permeability and the solute rejection were measured by PVDF membrane modified in different graft conditions. Results demonstrated that the pores in the modified membranes get smaller and the distribution of pores gets narrowed with the increase in grafting reaction duration. Longer graft time caused the water flux of PVDF membrane to decrease from 578 kg/(m^2· h) to 23 kg/(m^2· h) and the solute rejection to increase from 73% to 92%. 展开更多
关键词 Ar low-temperature plasma surface grafting STYRENE PVDF membrane
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PHOTOINDUCED GRAFTING OF ACRYLIC AND ALLYL MONOMERS ON POLYETHYLENE SURFACE
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作者 张振峰 胡兴洲 严庆 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 1995年第4期322-330,共9页
Photoinduced grafting of acrylic and allyl monomers on polyethylene surface was generally studied by using benzophenone (BP) as a photoinitiator. The grafting process was carried out either in vapor-phase or in soluti... Photoinduced grafting of acrylic and allyl monomers on polyethylene surface was generally studied by using benzophenone (BP) as a photoinitiator. The grafting process was carried out either in vapor-phase or in solution of the monomers. In the vapor-phase reaction with a filter used to cut off the short wavelength UV light, allyl amine is the most reactive of the four monomers used and acrylic amide is comparatively more reactive than acrylic acid and allyl alcohol. Acetone, as a solvent and carrier for initiator and monomers, however, shows its reactivity to participate the reaction. The solution grafting with a filter is much faster than the corresponding vapor-phase reaction, and a fully covered surface by the grafted polymer can be achieved in this way. 展开更多
关键词 UV light surface grafting POLYETHYLENE acrylic acid allyl alcohol allyl amine acrylic amide
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Polycaprolactone (PCL) Chains Grafting on the Surface of Cellulose Nanocrystals (CNCs) during <i>In Situ</i>Polymerization of <i>ε</i>-Caprolactone at Room Temperature
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作者 Jérémy Astruc Patrice Cousin +2 位作者 Gaétan Laroche Mathieu Robert Saïd Elkoun 《Materials Sciences and Applications》 2020年第11期744-756,共13页
This work aimed at investigating the feasibility of surface modification of cellulose nanocrystals (CNCs) using <em>in situ</em> ring opening polymerization of <em>ε</em>-caprolactone (<em&... This work aimed at investigating the feasibility of surface modification of cellulose nanocrystals (CNCs) using <em>in situ</em> ring opening polymerization of <em>ε</em>-caprolactone (<em>ε</em>-CL) at room temperature. Residues of flax and milkweed (<em>Asclepias syriaca</em>) stem fibers were used as a source of cellulose to obtain and isolate CNCs. The cationic ring opening polymerization (CROP) of the monomer <em>ε</em>-CL was used to covalently graft polycaprolactone (PCL) chains at the CNCs surface. Silver hexafluoroantimonate (AgSbF<sub>6</sub>) was used in combination with the extracted CNCs to initiate, at room temperature, the polymerization and the grafting reactions with no other stimulus. Fourier-Transform InfraRed (FTIR), X-ray Photoelectron Spectrometry (XPS), UV/visible absorption and Gel Permeation Chromatography (GPC) analyses evidenced the presence of PCL chains covalently grafted at CNCs surface, the formation of Ag(0) particles as well as low or moderate molecular weight free PCL chains. 展开更多
关键词 Cellulose Nanocrystals (CNCs) Simultaneous Polymerization and surface grafting ε-Caprolactone Cationic Ring Opening Polymerization Room Temperature Silver Hexafluoroantimonate
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LAMINATION OF POLYMER FILMS BY BULK SURFACE PHOTOGRAFTING PROCESS AND PROPERTIES 被引量:1
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作者 B.Rnby 杨万泰 +1 位作者 O.N.Tretinnikov V.Tokarev 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2001年第2期123-127,共5页
A new process for lamination of polymer films by 'bulk surface photografting' has been developed. The chemical component of the invention is that the curing of reactive solution between two substrates is initi... A new process for lamination of polymer films by 'bulk surface photografting' has been developed. The chemical component of the invention is that the curing of reactive solution between two substrates is initiated by the surface free radicals produced by aromatic ketones and surface-hydrogen of substrates. Using the new approach, two or more polymer films are bonded together by a grafted polymer network which is grafted to adjacent substrate surfaces. The technique has been applied to film substrates of different polymers such as polyolefins, polyesters, and polyamides which have abstractable hydrogens at the surface. The photolaminated film composites containing carrier films and an intermediate functional film of low permeability give strong laminates with high barrier properties, e.g, for oxygen and air. 展开更多
关键词 PHOTOgrafting LAMINATION surface graft polymerization photolamination
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Nitrate-group-grafting-induced assembly of rutile TiO2 nanobundles for enhanced photocatalytic hydrogen evolution 被引量:9
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作者 Heng Wang Xiantao Hu +3 位作者 Yajuan Ma Dajian Zhu Tao Li Jingyu Wang 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 北大核心 2020年第1期95-102,共8页
In this study,an acid-induced assembly strategy for a rutile TiO2 photocatalyst was proposed on the basis of the treatment of lamellar protonated titanate with a concentrated HNO3 solution.Nitrate groups were successf... In this study,an acid-induced assembly strategy for a rutile TiO2 photocatalyst was proposed on the basis of the treatment of lamellar protonated titanate with a concentrated HNO3 solution.Nitrate groups were successfully grafted onto a TiO2 surface and induced the assembly of rutile TiO2 nanorods into uniform spindle-like nanobundles.The resulting TiO2 product achieved a photocatalytic hydrogen evolution rate of 402.4μmol h^?1,which is 3.1 times higher than that of Degussa P25-TiO2.It was demonstrated that nitrate group grafting caused the rutile TiO2 surface to become negatively charged,which is favorable for trapping positive protons and improving charge carrier separation,thereby enhancing photocatalytic hydrogen production.Additionally,surface charges were crucial to structural stability based on electrostatic repulsion.This study not only developed a facile surface modification strategy for fabricating efficient H2 production photocatalysts but also identified an influence mechanism of inorganic acids different from that reported in the literature. 展开更多
关键词 Acid modification Rutile TiO2 surface grafting H2 production PHOTOCATALYSIS
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GRAFTING OF HYDROPHILIC MONOMERS ONTO POLYURETHANE MEMBRANES BY SOLUTION OR PRE-ABSORBING METHODS FOR ACCELERATION OF CELL COMPATIBILITY
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作者 Chang-you Gao Jian-jun Guan Jia-cong Shen Department of Polymer Science and Engineering Zhejiang University Hangzhou 310027, China 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2001年第5期493-498,共6页
Two grafting methods, i.e. solution grafting and pre-adsorbing, are introduced to covalently immobilizehydrophilic polymers on segmented polyurethane (SPU) to modify its hydrophilicity and to improve its cell compatib... Two grafting methods, i.e. solution grafting and pre-adsorbing, are introduced to covalently immobilizehydrophilic polymers on segmented polyurethane (SPU) to modify its hydrophilicity and to improve its cell compatibility.Solution grafting results in higher degree of grafting and rougher surface morphology. Cell culture evaluation demonstratesthat the modified membranes thus obtained are disadvantageous to the endothelial cell (ECs) growth probably because thehydrophilic groups on the surface are over-crowded. However, pre-absorbing grafting generates lower degree of grafting,which is detected and confirmed by ATR-FTIR spectra and water conted angle. Scanning electron microscopic (SEM)measurement shows that the latter method produces a plane and smooth morphology, which is similar to the SPU controlsample controlled. When grafting with lower monomer concentration, ECs could grow on SPU-g-PHEA [poly(2-hydroxyethyl acrylate)], SPU-g-PAAm (polyacrylamide), SPU-g-PDMA [poly(2-(dimethylamino)ethyl methacrylate)] orquatemized SPU-g-PDMA surface with elongated cell shapes. Hence, the cell compatibility of SPU is improved and a usefulmethod to construct a cell compatible layer on the polymer surface has been developed. 展开更多
关键词 segmented polyurethane cell compatibility surface grafting endothelial cell
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APPLICATION OF SURFACE GRAFTED POLY N-ISOPROPYL ACRYLAMIDE BY RADIATION TECHNOLOGY FOR PROTEIN SOLUTION CONCENTRATION
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作者 孙以实 李怀忠 +1 位作者 刘鹏飞 哈鸿飞 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 1991年第4期353-357,共5页
Poly N-isopropyl acrylamide (abbreviated as PNIPA) as a kind of thermally sensitive hydrogel is utilized to concentrate Bovin Serum Albumin (BSA) solution. In order to decrease its surface adsorption to BSA in aqueous... Poly N-isopropyl acrylamide (abbreviated as PNIPA) as a kind of thermally sensitive hydrogel is utilized to concentrate Bovin Serum Albumin (BSA) solution. In order to decrease its surface adsorption to BSA in aqueous solution, surface layer grafting of the gels by radiation technology was carried out. The results showed that hydroxyl propyl methacrylate (HPMA) grained gel exhibited a low level of BSA adsorption and still kept the original thermally sensitive properties of PNIPA hydrogels. 展开更多
关键词 Poly N-isopropylacrylamide hydroxyl propyl methacrylate Boving serum albumin thermally sensitive hydrogel radiation surface grafting
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Study on the Surface Modification of Hydrophobic Polyacrylate Intraocular Lens 被引量:2
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作者 TANG Hui-qin WANG Gui-qin GU Han-qing 《Chinese Journal of Biomedical Engineering(English Edition)》 2013年第1期29-36,共8页
In this study, the polyacrylate intraocularr lens is irradiated by argon ion which can produce free radicals. In order to obtain better hydrophilic and lower platelets adhesion, monomer vinyl pyrrolidone (NVP) is graf... In this study, the polyacrylate intraocularr lens is irradiated by argon ion which can produce free radicals. In order to obtain better hydrophilic and lower platelets adhesion, monomer vinyl pyrrolidone (NVP) is grafted onto the hydrophobic polyacrylate intraocular lens surface in a certain reaction conditions. Specific changes in intraocular lens are detected by static contact angle (CA), scanning electron microscope (SEM) and light transmittance. The results show that this surface modification can greatly improve its hydrophilic character and surface formation. 展开更多
关键词 hydrophobic polyacrylate intraocular lens vinyl pyrrolidone argon ion irradiation graft surface modification
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An Approach to the Flame Retardancy of EVA Copolymer by Plasma Treatmentc2
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作者 施来顺 王建祺 《Journal of Beijing Institute of Technology》 EI CAS 1997年第4期17-24,共8页
An attempt was made in the paper aiming at imparting flame retardancy to polymers by plasma grafting technique Based on EVA copolymers with different VA contents the author tried to use the Ar plasma followed by graf... An attempt was made in the paper aiming at imparting flame retardancy to polymers by plasma grafting technique Based on EVA copolymers with different VA contents the author tried to use the Ar plasma followed by grafting with/without subsequent saponification and metal ion exchange expediting the charring of polymers upon heationg Characterization of the flammability of the plasma treated EVA copolymers grafted with acrylic monomers(MAA,AA and AAm)indicates that this approach turns out to be a promising way and worthy doing whatever in research and/or applications 展开更多
关键词 flame retardancy surface grafting plasma EVA copolymer methylacrylic acid acrylic acid ACRYLAMIDE
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Preparation and shape memory properties of TiO_2/PLCL biodegradable polymer nanocomposites 被引量:3
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作者 鲁玺丽 吕秀乾 +2 位作者 王建永 孙志洁 佟运祥 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第1期120-127,共8页
The preparation of TiO2/poly(L-lactide-co-ε-caprolactone)(PLCL) nanocomposites and their properties were reported.TiO2nanoparticles were surface modified by ring-opening polymerization of ε-caprolactone(ε-CL)... The preparation of TiO2/poly(L-lactide-co-ε-caprolactone)(PLCL) nanocomposites and their properties were reported.TiO2nanoparticles were surface modified by ring-opening polymerization of ε-caprolactone(ε-CL).The resulting poly(ε-caprolactone)-grafted TiO2(g-TiO2) was characterized by Fourier transform infrared spectroscopy(FTIR),thermogravimetric analysis(TGA) and transmission electron microscopy(TEM).The g-TiO2can be uniformly dispersed in chloroform and the g-TiO2/PLCL nanocomposites were successfully fabricated through solvent-casting method.The effects of the content of g-TiO2nanoparticles on tensile properties and shape memory properties were investigated.A significant improvement in the tensile properties of the 5% g-TiO2/PLCL mass fraction nanocomposite is obtained:an increase of 113% in the tensile strength and an increase of 11% in the elongation at break over pure PLCL polymer.The g-TiO2/PLCL nanocomposites with a certain amount of g-TiO2content have better shape memory properties than pure PLCL polymer.The g-TiO2nanoparticles play an additional physical crosslinks which are contributed to improvement of the shape memory properties. 展开更多
关键词 poly(L-lactide-co-ε-caprolactone) NANOCOMPOSITES TiO2nanoparticles surface grafting shape memory properties mechanical properties
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Preparation of new hybrid organic/inorganic polymeric chiral stationary phases for ligand-exchange chromatography 被引量:2
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作者 Rui Juan Song Yu Fu +2 位作者 Na Yao Yuan De Long Tian Bao Huang 《Chinese Chemical Letters》 SCIE CAS CSCD 2007年第10期1250-1252,共3页
Three new hybrid organic/inorganic polymeric ligand-exchange chiral stationary phases were developed by radical chain transfer reaction and surface grafting on silica gel, and successfully used for the enantioseparati... Three new hybrid organic/inorganic polymeric ligand-exchange chiral stationary phases were developed by radical chain transfer reaction and surface grafting on silica gel, and successfully used for the enantioseparations of DL-amino acids and DL-hydroxyl adds. The resolutions were achieved by using water containing 2.0 × 10^-4 mol/L of CuAc2 as a mobile phase, column temperature of 40 ℃, flow rate of 1.0 mL/min and detection at UV 254 nm. The elution order of D-isomer before L-isomer was observed for all DL-amino acids resolved except DL-Pro. 展开更多
关键词 Chiral stationary phase Ligand-exchange chromatography DL-Hydroxyl acid surface grafting DL-Amino acid
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Thermal and mechanical properties and micro-mechanism of SiO_(2)/epoxy nanodielectrics
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作者 Tian-Yu Wang Gui-Xin Zhang Da-Yu Li 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第12期613-619,共7页
In addition to electrical insulation properties,the thermal properties of nanodielectrics,such as glass transition temperature,thermal expansion coefficients,thermal conductivity,and mechanical properties,including Yo... In addition to electrical insulation properties,the thermal properties of nanodielectrics,such as glass transition temperature,thermal expansion coefficients,thermal conductivity,and mechanical properties,including Young's modulus,bulk modulus,and shear modulus,are also very important.This paper describes the molecular dynamics simulations of epoxy resin doped with SiO_(2)nanoparticles and with SiO_(2)nanoparticles that have been surface grafted with hexamethyldisilazane(HMDS)at 10%and 20%grafting rates.The results show that surface grafting can improve certain thermal and mechanical properties of the system.Our analysis indicates that the improved thermal performance occurs because the formation of thermal chains becomes easier after the surface grafting treatment.The improved mechanical properties originate from two causes.First,doping with SiO_(2)nanoparticles inhibits the degree of movement of molecular chains in the system.Second,the surface grafting treatment weakens the molecular repulsion between SiO_(2)and epoxy resin,and the van der Waals excluded region becomes thinner.Thus,the compatibility between SiO_(2)nanoparticles and polymers is improved by the grafting treatment.The analysis method and conclusions in this paper provide guidance and reference for the future studies of the thermal and mechanical properties of nanodielectrics. 展开更多
关键词 nanodielectric surface grafting treatment molecular dynamics simulation interface properties
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Grafting of PEG400 onto the surface of LLDPE/SMA film
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作者 CHEN Gufeng ZHANG Yi +1 位作者 ZHU Yafei XU Jiarui 《Frontiers of Chemical Science and Engineering》 SCIE EI CSCD 2007年第2期128-131,共4页
Linear low-density polyethylene(LLDPE)was melt and blended with styrene-maleic anhydride copolymer(SMA).The blending films were then immersed in poly(ethylene glycol)400(PEG400)at room temperature.The surface composit... Linear low-density polyethylene(LLDPE)was melt and blended with styrene-maleic anhydride copolymer(SMA).The blending films were then immersed in poly(ethylene glycol)400(PEG400)at room temperature.The surface composition of the blend films was determined by Fourier transform infra-red spectroscopy coupled with a variable incidence angle attenuated total reflection accessory(ATR-FTIR).Results show that PEG400 can be grafted onto the surface of the films via esterification with SMA.The immersion of PEG promotes the enrichment of SMA onto the surface of the films.The water contact angle data show that grafting of PEG400 onto PE can greatly improve the hydro-philicity of the PE surface.These experiments show that sur-face functionalization of polyethylene films by blending SMA and then surface grafting of PEG is feasible,which suggest an effective and simple route for PE surface modification via blending and grafting. 展开更多
关键词 polyethylene surface modification styrene-maleic anhydride copolymer poly(ethylene glycol) surface grafting
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PLASMA MODIFICATION OF POLYPROPYLENE SURFACES AND GRAFTING COPOLYMERIZATION OF STYRENE ONTO POLYPROPYLENE 被引量:6
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作者 马桂秋 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2012年第3期423-435,共13页
The surface of polypropylene (iPP) is modified with glow discharge plasma of Ar, so that the modified surfaces of iPP films are obtained. The studies of scanning electron microscopy (SEM) show the surface etching ... The surface of polypropylene (iPP) is modified with glow discharge plasma of Ar, so that the modified surfaces of iPP films are obtained. The studies of scanning electron microscopy (SEM) show the surface etching pattern of iPP films. The chemical structures of iPP films are confirmed by X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FTIR) spectroscopy. The wetting properties of modified surfaces of iPP films are characterized by contact angle, and the free energy of surfaces is calculated. The free radical of modification surfaces of iPP is measured by chemical method. The surfaces of iPP are achieved with Ar plasma treatment followed by grafting copolymerization with styrene (St) in St. The grafting polymer of St onto iPP is characterized by FTIR. The grafting rate is dependent on plasma exposure time and discharge voltage. The studies show that homopolymerization of St is undergone at the sane time during the graftingcopolymerization of St onto/PP. 展开更多
关键词 Plasma treatment of polymer surface Plasma modification of polypropylene grafting copolymerization of polypropylene surface.
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Recent developments in functional organic polymer coatings for biomedical applications in implanted devices
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作者 Yinuo YANG Yiran JIA +2 位作者 Yanran ZHAO Haimang WANG Hongyu ZHANG 《Friction》 SCIE EI CAS CSCD 2024年第11期2399-2440,F0004,共43页
Organic polymer coatings have been commonly used in biomedical field,which play an important role in achieving biological antifouling,drug delivery,and bacteriostasis.With the continuous development of polymer science... Organic polymer coatings have been commonly used in biomedical field,which play an important role in achieving biological antifouling,drug delivery,and bacteriostasis.With the continuous development of polymer science,organic polymer coatings can be designed with complex and advanced functions,which is conducive to the construction of biomedical materials with different performances.According to different physical and chemical properties of materials,biomedical organic polymer coating materials are classified into zwitterionic polymers,non-ionic polymers,and biomacromolecules.The strategies of combining coatings with substrates include physical adsorption,chemical grafting,and self-adhesion.Though the coating materials and construction methods are different,many biomedical polymer coatings have been developed to achieve excellent performances,i.e.,enhanced lubrication,anti-inflammation,antifouling,antibacterial,drug release,anti-encrustation,anti-thrombosis,etc.Consequently,a large number of biomedical polymer coatings have been used in artificial lungs,ureteral stent,vascular flow diverter,and artificial joints.In this review,we summarize different types,properties,construction methods,biological functions,and clinical applications of biomedical organic polymer coatings,and prospect future direction for development of organic polymer coatings in biomedical field.It is anticipated that this review can be useful for the design and synthesis of functional organic polymer coatings with various biomedical purposes. 展开更多
关键词 organic polymer coating implanted biomedical device surface grafting method biological performance clinical application
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Smart biomaterials: Surfaces functionalized with proteolytically stable osteoblast-adhesive peptides 被引量:3
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作者 Annj Zamuner Paola Brun +3 位作者 Michele Scorzeto Giuseppe Sica Ignazio Castagliuolo Monica Dettin 《Bioactive Materials》 SCIE 2017年第3期121-130,共10页
Engineered scaffolds for bone tissue regeneration are designed to promote cell adhesion,growth,proliferation and differentiation.Recently,covalent and selective functionalization of glass and titanium surfaces with an... Engineered scaffolds for bone tissue regeneration are designed to promote cell adhesion,growth,proliferation and differentiation.Recently,covalent and selective functionalization of glass and titanium surfaces with an adhesive peptide(HVP)mapped on[351e359]sequence of human Vitronectin allowed to selectively increase osteoblast attachment and adhesion strength in in vitro assays,and to promote osseointegration in in vivo studies.For the first time to our knowledge,in this study we investigated the resistance of adhesion sequences to proteolytic digestion:HVP was completely cleaved after 5 h.In order to overcome the enzymatic degradation of the native peptide under physiological conditions we synthetized three analogues of HVP sequence.A retro-inverted peptide D-2HVP,composed of D amino acids,was completely stable in serum-containing medium.In addition,glass surfaces functionalized with D-2HVP increased human osteoblast adhesion as compared to the native peptide and maintained deposition of calcium.Interestingly,D-2HVP increased expression of IBSP,VTN and SPP1 genes as compared to HVP functionalized surfaces.Total internal reflection fluorescence microscope analysis showed cells with numerous filopodia spread on D-2HVP-functionalized surfaces.Therefore,the D-2HVP sequence is proposed as new osteoblast adhesive peptide with increased bioactivity and high proteolytic resistance. 展开更多
关键词 Adhesive sequences Retro-inverso peptides surface grafting Proteolytic degradation OSTEOBLAST TIRF
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Preparation of a PTE simulacrum based on surface molecular imprinting 被引量:1
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作者 Yong Guo Ying Yang Tian Ying Guo 《Chinese Chemical Letters》 SCIE CAS CSCD 2011年第4期493-496,共4页
Firstly,we synthesized N-methacryloyl-histidine monomer and N-methacryloyl-histidine-Cu^2+ complex(MAH-Cu^2+).Then the molecular imprinting polymers(MIP) has been prepared by surface grafting on uniform polystyr... Firstly,we synthesized N-methacryloyl-histidine monomer and N-methacryloyl-histidine-Cu^2+ complex(MAH-Cu^2+).Then the molecular imprinting polymers(MIP) has been prepared by surface grafting on uniform polystyrene(PS) core using reversible addition-fragmentation transfer polymerization(RAFT) with MAH-Cu^2+ as the functional monomer,methyl paraoxon as the template to simulate phosphodiesterase(PTE).Finally,we have investigated the catalytic hydrolytic activities of MIP and non-imprinting polymers(NIP) to the template methyl paraoxon and the template analogue ethyl paraoxon respectively by UV spectrophotometry.The results showed that the catalytic hydrolytic activity of MIP to the template methyl paraoxon was highest and the value of k is 8.67×10^-5 mmol L^-1 min^-1,3.89-fold higher than MIP to the template analogue ethyl paraoxon,2.79-fold higher than NIP to the template methyl paraoxon.The KM,rm of MSP are also determined,and KM = 3.95×10^-4)mol/L,rm = 2.12μmol/ min.The MIP can be reused with only lose 7%of catalytic activity for four cycles. 展开更多
关键词 Molecular imprinting surface grafting Catalytic hydrolysis PARAOXON
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Liquid crystal of nanocellulose whiskers' grafted with acrylamide 被引量:6
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作者 Jie Yang Dai Yong Ye 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第3期367-370,共4页
12%acrylamide(AM) was grafted onto the surface of nanocellulose whiskers(NCW),which was self-assembled to be the chiral nematic suspension at 3%content.The acrylamide grafted NCW(AM-g-NCW) was characterized with... 12%acrylamide(AM) was grafted onto the surface of nanocellulose whiskers(NCW),which was self-assembled to be the chiral nematic suspension at 3%content.The acrylamide grafted NCW(AM-g-NCW) was characterized with Fourier Transform Infrared Spectroscopy(FTIR).The grafting ratio was measured by elemental analysis.The degrees of crystallinity of the AM-g-NCW were measured by X-ray diffraction(XRD).The liquid crystalline properties of the AM-g-NCW were investigated by the polarizing optical microscopy(POM).The AM-g-NCW was found to self-assembly to be a lyotropic state. 展开更多
关键词 Nanocellulose whiskers ACRYLAMIDE surface grafting Liquid crystal
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