The new type of embedded signal processing system based on the packet switched network is achieved. According to the application field and the characteristics of signal processing system, the RapidIO protocol is used ...The new type of embedded signal processing system based on the packet switched network is achieved. According to the application field and the characteristics of signal processing system, the RapidIO protocol is used to solve the high-speed interconnection of multi-digital signal processor (DSP). Based on this protocol, a kind of crossbar switch module which is used to interconnect multi-DSP in the system is introduced. A route strategy, some flow control rules and error control rules, which adapt to different RapidIO network topology are also introduced. Crossbar switch performance is analyzed in detail by the probability module. By researching the technique of crossbar switch and analyzing the system performance, it has a significant meaning for building the general signal processing system.展开更多
A novel and accurate method is proposed to extract the intrinsic elements of the GaN high-electron-mobility transistor(HEMT) switch.The new extraction method is verified by comparing the simulated S-parameters with th...A novel and accurate method is proposed to extract the intrinsic elements of the GaN high-electron-mobility transistor(HEMT) switch.The new extraction method is verified by comparing the simulated S-parameters with the measured data over the 5-40 GHz frequency range.The percentage errors E_(ij) within 3.83% show the great agreement between the simulated S-parameters and the measured data.展开更多
By applying switch-signal theory, the interaction between MOS transmission switch-ing transistor and current signal in current-mode CMOS circuits is analyzed, and the theory oftransmission current-switches which is su...By applying switch-signal theory, the interaction between MOS transmission switch-ing transistor and current signal in current-mode CMOS circuits is analyzed, and the theory oftransmission current-switches which is suitable to current-mode CMOS circuits is proposed. Thecircuits, such as ternary full-adder etc., designed by using this theory have simpler circuit struc-tures and correct logic functions. It is confirmed that this theory is efficient in guiding the logicdesign of current-mode CMOS circuits at switch level.展开更多
This paper presents an accurate small-signal model for multi-gate GaAs pHEMTs in switching-mode.The extraction method for the proposed model is developed.A 2-gate switch structure is fabricated on a commercial 0.5μm ...This paper presents an accurate small-signal model for multi-gate GaAs pHEMTs in switching-mode.The extraction method for the proposed model is developed.A 2-gate switch structure is fabricated on a commercial 0.5μm AlGaAs/GaAs pHEMT technology to verify the proposed model.Excellent agreement has been obtained between the measured and simulated results over a wide frequency range.展开更多
Numerical simulation of diode-pumped Q-switched Nd:YAG laser leading to the generation of eye-safe signal in singly resonant Intracavity Optical Parametric Oscillator (IOPO) is presented. Starting from rate equations,...Numerical simulation of diode-pumped Q-switched Nd:YAG laser leading to the generation of eye-safe signal in singly resonant Intracavity Optical Parametric Oscillator (IOPO) is presented. Starting from rate equations, the time dependent laser equations have been solved numerically, whereas the space-dependent OPO equations analytically. Our results show that 1.4 J diode laser (810 nm) pulse with 200 msec width, delivers 30 mJ Nd:YAG laser (1064 nm) pulse with 5 n-second width. This Nd:YAG laser further generates 9 mJ eye safe signal (1570 nm) pulse with 2.5 n-second width.展开更多
The soluble HLA-G1 (sHLA-G1) isoform was found to be secreted by trophoblast cells at the materno-fetal interface,which suggests that it may act as an immunomodulator during pregnancy. In this paper, we reported that ...The soluble HLA-G1 (sHLA-G1) isoform was found to be secreted by trophoblast cells at the materno-fetal interface,which suggests that it may act as an immunomodulator during pregnancy. In this paper, we reported that GST-sHLA-G1α chain could bind to its receptor ILT-2 on NK92 cells and then the latter recruited Src homology 2 domaincontaining tyrosine phosphatase-1 (SHP-1), which consequently dephosphorylated some important protein tyrosine kinases and blocked the activation of downstream molecules such as MEK and ERK so that the cytotoxicity of natural killer (NK) cells was inhibited. These results indicated that GST-sHLA-G1α chain might be exploited in new immunotherapy strategies aiming at inducing immunotolerance during allograft, xenograft and autoimmune situations. In addition,we found that modification of O-linked β-N-acetylglucosamine (O-GlcNAc) was involved in NK cells' activating and inhibitory signals. This may provide a novel molecular target for inducing immunotolerance but needs further study.展开更多
Xingcuo lake,a closed one,is situated in eastern Tibetan Plateau.There are abundant snail shells Gy-raulus sibirica in its sediments.Here we display the determining results ofδ 13 C,δ 18 O in shell Gyraulus sibirica...Xingcuo lake,a closed one,is situated in eastern Tibetan Plateau.There are abundant snail shells Gy-raulus sibirica in its sediments.Here we display the determining results ofδ 13 C,δ 18 O in shell Gyraulus sibirica continuous-ly preserved in Xincuo Lake sediment s in the recent 50years.And by coupling the indexes ofδ 13 C,δ 18 O and instrumen-tal meteorological data in its basin to build relative function relation s among them,we probe quantitatively climatic sig-nals recorded in those indexes.The r esults show that there are remarkabl e relations betweenδ 13 C proxy and precipitation,δ 18 Oproxy and air temperature,of which correlative coefficient was 0.89an d 0.71,respectively.Besides,we also demon-strated that average variation betw eenδ 13 C proxy and precipitation(dδ 13 C /dP)was 0.027‰/mm and 1.64‰/℃forδ 18 O and air temperature(dδ 18 O /dT).展开更多
ZnMn_2O_4 thin films were deposited by a sol-gel technique onto a p+-Si substrate, and a RRAM device with the Ag/ZnMn_2O_4/p^+-Si structure was fabricated. The microstructure of ZnMn_2O_4 films and the resistive switc...ZnMn_2O_4 thin films were deposited by a sol-gel technique onto a p+-Si substrate, and a RRAM device with the Ag/ZnMn_2O_4/p^+-Si structure was fabricated. The microstructure of ZnMn_2O_4 films and the resistive switching behavior of Ag/ZnMn_2O_4/p^+-Si device were investigated. ZnMn_2O_4 thin films had a spinel structure after annealing at 650 °C for 1 h. The Ag/ZnMn_2O_4/p^+-Si device showed unipolar and/or bipolar resistive switching behavior, exhibiting different ION/IOFF ratio and switching endurance properties. In bipolar resistive switching, high-resistance-state(HRS) conduction was dominated by the space-charge-limited conduction mechanism, whereas the filament conduction mechanism dictated the low resistance state(LRS). For unipolar resistive switching, HRS and LRS were controlled by the filament conduction mechanism. For bipolar resistive switching, the conduction process can be explained by the space-charge region of the p-n junction.展开更多
Prostate cancer is one of the most often diagnosed malignancies in males and its prevalence is rising in both developed and developing countries.Androgen deprivation therapy has been used as a standard treatment appro...Prostate cancer is one of the most often diagnosed malignancies in males and its prevalence is rising in both developed and developing countries.Androgen deprivation therapy has been used as a standard treatment approach for advanced prostate cancer for more than 80 years.The primary aim of androgen deprivation therapy is to decrease circulatory androgen and block androgen signaling.Although a partly remediation is accomplished at the beginning of treatment,some cell populations become refractory to androgen deprivation therapy and continue to metastasize.Recent evidences suggest that androgen deprivation therapy may cause cadherin switching,from E-cadherin to N-cadherin,which is the hallmark of epithelial-mesenchymal transition.Diverse direct and indirect mechanisms are involved in this switching and consequently,the cadherin pool changes from E-cadherin to N-cadherin in the epithelial cells.Since E-cadherin represses invasive and migrative behaviors of the tumor cells,the loss of E-cadherin disrupts epithelial tissue structure leading to the release of tumor cells into surrounding tissues and circulation.In this study,we review the androgen deprivation therapy-dependent cadherin switching in advanced prostate cancer with emphasis on its molecular basis especially the transcriptional factors regulated through TFG-βpathway.展开更多
A diode-pumped acousto-op ti cal(A-O) Q-switched extra-cavity frequency-doubled Nd∶YVO_ 4/ KTP (KTiO PO_ 4) green laser formed with a simple plane-plane cavity has been demonst rated. With the incident pump power of ...A diode-pumped acousto-op ti cal(A-O) Q-switched extra-cavity frequency-doubled Nd∶YVO_ 4/ KTP (KTiO PO_ 4) green laser formed with a simple plane-plane cavity has been demonst rated. With the incident pump power of 12.7 W, A-O Q-switched average output power at 1 064 nm was 3.81 W with a duration of 25 ns at a repetition rate of 20 kHz, extra-cavity frequency doubling with KTP as the nonlinear crystal y ielded the maximum output power of 1.92 W at 532 nm, the corresponding optical conversion efficiency from 1 064 nm to 532 nm light is 50.4%. The continuous -wave(CW) laser properties of diode-pumped Nd∶YVO_ 4 crystal operating at 1 064 nm have been studied. With the incident pump power of 25 W, the maximu m CW output power of 13.81 W was obtained with the corresponding optical conver sion efficiency of 55.24%.展开更多
A high power continuous wave (CW) laser diode (LD) pumped acousto-optic Q-switched Nd:YVO4 laser is presented. A short pulse at the 1064 nm is obtained. With a repetition rate of 50 kHz,the maximum average output powe...A high power continuous wave (CW) laser diode (LD) pumped acousto-optic Q-switched Nd:YVO4 laser is presented. A short pulse at the 1064 nm is obtained. With a repetition rate of 50 kHz,the maximum average output power of 5.72 W is achieved. The optical conversion efficiency and the slope efficiency are up to 28% and 32.4% respectively. At the repetition rate of 10 kHz and the pulse width of 16.3ns, the maximum single pulse energy of 286 μJ and the peak power of 13kW are acquired. The laser can be used as a signal source in the free-space optical communication. The output signal agrees with the modulate signal well.展开更多
Auditory sense is an important way for people to receive and interact with foreign information.In different environment,the auditory sense changes.Therefore,it is necessary to find a detection method that can detect h...Auditory sense is an important way for people to receive and interact with foreign information.In different environment,the auditory sense changes.Therefore,it is necessary to find a detection method that can detect hearing in a timely manner.In this paper,EEG experiments were used to construct and compare brain functional networks in different states,and auditory state models were constructed with different auditory input signals.Secondly,the cross-correlation method is used to slice the signal and construct the adjacency matrix.Louvain community detection algorithm is used to process the data and calculate the network conversion rate under different parameters.It is concluded that the network conversion rate can be used to analyze the temporal variation of auditory information under the condition of controlled parameters.This indicates that the network conversion rate can also be used as a method to analyze auditory signals in the future.展开更多
文摘The new type of embedded signal processing system based on the packet switched network is achieved. According to the application field and the characteristics of signal processing system, the RapidIO protocol is used to solve the high-speed interconnection of multi-digital signal processor (DSP). Based on this protocol, a kind of crossbar switch module which is used to interconnect multi-DSP in the system is introduced. A route strategy, some flow control rules and error control rules, which adapt to different RapidIO network topology are also introduced. Crossbar switch performance is analyzed in detail by the probability module. By researching the technique of crossbar switch and analyzing the system performance, it has a significant meaning for building the general signal processing system.
文摘A novel and accurate method is proposed to extract the intrinsic elements of the GaN high-electron-mobility transistor(HEMT) switch.The new extraction method is verified by comparing the simulated S-parameters with the measured data over the 5-40 GHz frequency range.The percentage errors E_(ij) within 3.83% show the great agreement between the simulated S-parameters and the measured data.
基金Supported by National Natural Science Foundation of China
文摘By applying switch-signal theory, the interaction between MOS transmission switch-ing transistor and current signal in current-mode CMOS circuits is analyzed, and the theory oftransmission current-switches which is suitable to current-mode CMOS circuits is proposed. Thecircuits, such as ternary full-adder etc., designed by using this theory have simpler circuit struc-tures and correct logic functions. It is confirmed that this theory is efficient in guiding the logicdesign of current-mode CMOS circuits at switch level.
文摘This paper presents an accurate small-signal model for multi-gate GaAs pHEMTs in switching-mode.The extraction method for the proposed model is developed.A 2-gate switch structure is fabricated on a commercial 0.5μm AlGaAs/GaAs pHEMT technology to verify the proposed model.Excellent agreement has been obtained between the measured and simulated results over a wide frequency range.
文摘Numerical simulation of diode-pumped Q-switched Nd:YAG laser leading to the generation of eye-safe signal in singly resonant Intracavity Optical Parametric Oscillator (IOPO) is presented. Starting from rate equations, the time dependent laser equations have been solved numerically, whereas the space-dependent OPO equations analytically. Our results show that 1.4 J diode laser (810 nm) pulse with 200 msec width, delivers 30 mJ Nd:YAG laser (1064 nm) pulse with 5 n-second width. This Nd:YAG laser further generates 9 mJ eye safe signal (1570 nm) pulse with 2.5 n-second width.
基金Supported by National Natural Science Foundation ot China （61203065, 61120106009）, the Program of Natural Science of Henan Provincial Education Department （12A510013）, and the Program of Open Laboratory Foundation of Control Engineering Key Discipline of Henan Provincial High Education （KG 2011-10）
文摘在这份报纸，反复的学习控制(ILC ) 与任意的切换的信号为线性分离时间的交换系统的一个类被考虑。交换系统重复地在有限时间间隔期间被操作，这被假定，然后第一个顺序 P 类型 ILC 计划能被用来完成完美的追踪在上自始至终间隔。由超级向量途径，为在重复领域的如此的 ILC 系统的一个集中条件能被给。理论分析被模拟支持。
文摘The soluble HLA-G1 (sHLA-G1) isoform was found to be secreted by trophoblast cells at the materno-fetal interface,which suggests that it may act as an immunomodulator during pregnancy. In this paper, we reported that GST-sHLA-G1α chain could bind to its receptor ILT-2 on NK92 cells and then the latter recruited Src homology 2 domaincontaining tyrosine phosphatase-1 (SHP-1), which consequently dephosphorylated some important protein tyrosine kinases and blocked the activation of downstream molecules such as MEK and ERK so that the cytotoxicity of natural killer (NK) cells was inhibited. These results indicated that GST-sHLA-G1α chain might be exploited in new immunotherapy strategies aiming at inducing immunotolerance during allograft, xenograft and autoimmune situations. In addition,we found that modification of O-linked β-N-acetylglucosamine (O-GlcNAc) was involved in NK cells' activating and inhibitory signals. This may provide a novel molecular target for inducing immunotolerance but needs further study.
文摘Xingcuo lake,a closed one,is situated in eastern Tibetan Plateau.There are abundant snail shells Gy-raulus sibirica in its sediments.Here we display the determining results ofδ 13 C,δ 18 O in shell Gyraulus sibirica continuous-ly preserved in Xincuo Lake sediment s in the recent 50years.And by coupling the indexes ofδ 13 C,δ 18 O and instrumen-tal meteorological data in its basin to build relative function relation s among them,we probe quantitatively climatic sig-nals recorded in those indexes.The r esults show that there are remarkabl e relations betweenδ 13 C proxy and precipitation,δ 18 Oproxy and air temperature,of which correlative coefficient was 0.89an d 0.71,respectively.Besides,we also demon-strated that average variation betw eenδ 13 C proxy and precipitation(dδ 13 C /dP)was 0.027‰/mm and 1.64‰/℃forδ 18 O and air temperature(dδ 18 O /dT).
基金Funded by the National Natural Science Foundation of China(No.51262003)the Guangxi Key Laboratory of Information Materials(Guilin University of Electronic Technology),China(No.1110908-10-Z)
文摘ZnMn_2O_4 thin films were deposited by a sol-gel technique onto a p+-Si substrate, and a RRAM device with the Ag/ZnMn_2O_4/p^+-Si structure was fabricated. The microstructure of ZnMn_2O_4 films and the resistive switching behavior of Ag/ZnMn_2O_4/p^+-Si device were investigated. ZnMn_2O_4 thin films had a spinel structure after annealing at 650 °C for 1 h. The Ag/ZnMn_2O_4/p^+-Si device showed unipolar and/or bipolar resistive switching behavior, exhibiting different ION/IOFF ratio and switching endurance properties. In bipolar resistive switching, high-resistance-state(HRS) conduction was dominated by the space-charge-limited conduction mechanism, whereas the filament conduction mechanism dictated the low resistance state(LRS). For unipolar resistive switching, HRS and LRS were controlled by the filament conduction mechanism. For bipolar resistive switching, the conduction process can be explained by the space-charge region of the p-n junction.
文摘Prostate cancer is one of the most often diagnosed malignancies in males and its prevalence is rising in both developed and developing countries.Androgen deprivation therapy has been used as a standard treatment approach for advanced prostate cancer for more than 80 years.The primary aim of androgen deprivation therapy is to decrease circulatory androgen and block androgen signaling.Although a partly remediation is accomplished at the beginning of treatment,some cell populations become refractory to androgen deprivation therapy and continue to metastasize.Recent evidences suggest that androgen deprivation therapy may cause cadherin switching,from E-cadherin to N-cadherin,which is the hallmark of epithelial-mesenchymal transition.Diverse direct and indirect mechanisms are involved in this switching and consequently,the cadherin pool changes from E-cadherin to N-cadherin in the epithelial cells.Since E-cadherin represses invasive and migrative behaviors of the tumor cells,the loss of E-cadherin disrupts epithelial tissue structure leading to the release of tumor cells into surrounding tissues and circulation.In this study,we review the androgen deprivation therapy-dependent cadherin switching in advanced prostate cancer with emphasis on its molecular basis especially the transcriptional factors regulated through TFG-βpathway.
文摘提出了一种2.5维(2.5D)系统封装高速输入/输出(I/O)全链路的信号/电源完整性(Signal integrity/power integrity,SI/PI)协同仿真方法。首先通过电磁全波仿真分析SiP内部“芯片I/O引脚-有源转接板-印刷电路板(即封装基板)-封装体I/O引脚”这一主要高速信号链路及相应的转接板/印刷电路板电源分配网络(Power distribution network,PDN)的结构特征和电学特性,在此基础上分别搭建对应有源转接板和印刷电路板两种组装层级的“信号链路+PDN”模型,并分别进行SI/PI协同仿真,提取出反映信号链路/PDN耦合特性的模块化集总电路模型,从而在电路仿真器中以级联模型实现快速的SI/PI协同仿真。与全链路的全波仿真结果的对比表明,模块化后的协同仿真有很好的可信度,而且仿真时间与资源开销大幅缩减,效率明显提升。同时总结了去耦电容的大小与布局密度对PDN电源完整性的影响及对信号完整性的潜在影响,提出了去耦电容布局优化的建议。
基金Key Project of Natural Science Foundation from Shandong Province(Z2003A01)
文摘A diode-pumped acousto-op ti cal(A-O) Q-switched extra-cavity frequency-doubled Nd∶YVO_ 4/ KTP (KTiO PO_ 4) green laser formed with a simple plane-plane cavity has been demonst rated. With the incident pump power of 12.7 W, A-O Q-switched average output power at 1 064 nm was 3.81 W with a duration of 25 ns at a repetition rate of 20 kHz, extra-cavity frequency doubling with KTP as the nonlinear crystal y ielded the maximum output power of 1.92 W at 532 nm, the corresponding optical conversion efficiency from 1 064 nm to 532 nm light is 50.4%. The continuous -wave(CW) laser properties of diode-pumped Nd∶YVO_ 4 crystal operating at 1 064 nm have been studied. With the incident pump power of 25 W, the maximu m CW output power of 13.81 W was obtained with the corresponding optical conver sion efficiency of 55.24%.
文摘A high power continuous wave (CW) laser diode (LD) pumped acousto-optic Q-switched Nd:YVO4 laser is presented. A short pulse at the 1064 nm is obtained. With a repetition rate of 50 kHz,the maximum average output power of 5.72 W is achieved. The optical conversion efficiency and the slope efficiency are up to 28% and 32.4% respectively. At the repetition rate of 10 kHz and the pulse width of 16.3ns, the maximum single pulse energy of 286 μJ and the peak power of 13kW are acquired. The laser can be used as a signal source in the free-space optical communication. The output signal agrees with the modulate signal well.
文摘Auditory sense is an important way for people to receive and interact with foreign information.In different environment,the auditory sense changes.Therefore,it is necessary to find a detection method that can detect hearing in a timely manner.In this paper,EEG experiments were used to construct and compare brain functional networks in different states,and auditory state models were constructed with different auditory input signals.Secondly,the cross-correlation method is used to slice the signal and construct the adjacency matrix.Louvain community detection algorithm is used to process the data and calculate the network conversion rate under different parameters.It is concluded that the network conversion rate can be used to analyze the temporal variation of auditory information under the condition of controlled parameters.This indicates that the network conversion rate can also be used as a method to analyze auditory signals in the future.
