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Observation on the Nursing Effect of Ginger Moxibustion on Gastrointestinal Symptoms in Patients with Heart Failure Due to Yang Qi Deficiency
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作者 Yijing Wang 《Journal of Clinical and Nursing Research》 2024年第6期135-141,共7页
Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi defi... Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi deficiency type)accompanied by gastrointestinal symptoms who were admitted to the hospital between January 2023 and January 2024 were selected and divided into 43 cases in each group by random number table grouping;Group I implemented integrated care,while Group II adopted conventional care.The indicators of care were compared between the two groups.Results:After the nursing care,the digestive symptom scores of Group I were lower than those of Group I,and the psychological scores were lower than those of Group II(P<0.05).Conclusion:Ginger moxibustion can improve gastrointestinal symptoms and enhance the psychological health of patients with heart failure(yang qi deficiency type)with gastrointestinal symptoms. 展开更多
关键词 Ginger moxibustion Yang qi deficiency Heart failure Gastrointestinal symptoms
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Dietary Habits in Patients with Ulcerative Colitis—Cause of Nutrient Deficiency? 被引量:1
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作者 U. Bach H. N. Jensen +2 位作者 H. H. Rasmussen J. Fallingborg M. Holst 《Food and Nutrition Sciences》 2014年第20期1945-1950,共6页
Background: Up to 60% of patients with ulcerative colitis are seen with nutrient deficiency;however, no specific diet is recommended. The aim of this study was to obtain knowledge on whether restriction or addition of... Background: Up to 60% of patients with ulcerative colitis are seen with nutrient deficiency;however, no specific diet is recommended. The aim of this study was to obtain knowledge on whether restriction or addition of specific food items might contribute to malnutrition in these patients. Methods: A qualitative semi-structured interview study of outpatient clinic patients with ulcerative colitis aimed to investigate preferences for or avoidance of specific food items related to abdominal symptoms. Results: The study included 25 patients (12 M, 13 F), average age 46.7 years (SD 15.6). Duration of disease ranged from 1 to 35 years. Restriction of food items was mainly due to discomfort associated with bowel symptoms, e.g. diarrhoea caused by sugar, dairies, alcohol, spices, red meat, and bread. Restrictions were based mainly on personal experience rather than professional guidance or knowledge search. Addition of specific food items most often included vitamin supplements. Only 20% took supplementary calcium, although many restricted the consumption of dairies from their diet. Conclusion: Many patients with ulcerative colitis restrict consumption of dairy products from their diet. This may lead to calcium deficiency. No other dietary restrictions, which might explain specific nutrient deficiencies, were identified. 展开更多
关键词 ULCERATIVE COLITIS MALNUTRITION ABDOMINAL symptomS RESTRICTION Calcium deficiency Diet
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The Effects of a Primary Nutritional Deficiency (Vitamin B study) 被引量:1
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作者 Hugh D. Riordan Nina Mikirova +2 位作者 Paul R. Taylor Cindy A. Feldkamp Joseph J. Casciari 《Food and Nutrition Sciences》 2012年第9期1238-1244,共7页
It has long been understood there is a link between a nutrient deficiency and visually measurable health. In separate studies, Sprague Dawley or Fischer 344 rats were fed diets lacking 100% of one B-Vitamin until a si... It has long been understood there is a link between a nutrient deficiency and visually measurable health. In separate studies, Sprague Dawley or Fischer 344 rats were fed diets lacking 100% of one B-Vitamin until a single mortality occurred. Vitamins studied were thiamin, riboflavin, niacin, pyridoxine, pantothenic acid, cobalamin and folate. Body mass, food consumption and images were recorded at weekly intervals. Rats were euthanized and liver, kidney, heart and brain samples for histological analysis were prepared. Liver and brain tissues were chosen as markers because of the high need of that organ for B vitamins and the likelihood of secondary lesion development. Correlation of deficiency symptoms with one missing nutrient was explored. 展开更多
关键词 Essential NUTRIENTS B VITAMINS deficiency symptomS ANIMAL STUDY
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Emergence of lesions outside of the basal ganglia and irreversible damage to the basal ganglia with severeβ-ketothiolase deficiency:A case report 被引量:1
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作者 Jun Guo Dan Ren +4 位作者 Zhong-Jie Guo Jing Yu Fu Liu Rong-Xiang Zhao Yu Wang 《World Journal of Clinical Cases》 SCIE 2021年第30期9276-9284,共9页
BACKGROUNDβ-ketothiolase deficiency(β-KTD)is an inherited disease,and insufficient attention has been paid to imageology due to its lower morbidity.Therefore,few lesions outside the basal ganglia have been found bef... BACKGROUNDβ-ketothiolase deficiency(β-KTD)is an inherited disease,and insufficient attention has been paid to imageology due to its lower morbidity.Therefore,few lesions outside the basal ganglia have been found before,and the persistent pathological changes have rarely been reported.CASE SUMMARY A 10-mo-old Chinese female patient with a free previous medical history but with poor physical and athletic development had received the haemophilus influenzae vaccine and then developed a low fever 2 d prior.She was initially diagnosed with severe brain injury,central respiratory failure,metabolic acidosis complicated with respiratory alkalosis,hyper-IgE,etc.With further examination,a definite diagnosis ofβ-KTD was made.Symptomatic treatment was adopted.Ten days later,the dyspnea was improved evidently and the ventilator was removed,but there were still obvious abnormalities on magnetic resonance imaging(MRI).The lesions mainly invaded the corpus striatum but were not limited to the basal ganglia.Then,the patient’s disease improved and discharged approximately 1 mo later,and the abnormal lesions on MRI had partially improved.However,for about 1 year,the residual irreversible lesions were observed on MRI,the mental and physical development of the patient was obviously regressive,and extra rehabilitation training was needed.CONCLUSION The case highlights the critical importance of one view that the range of lesions in some patients may be more extensive than previously thought in someβ-KTD patients.In addition to biochemical tests,genetic tests and magnetic resonance imaging are not only conducive to quickly diagnosingβ-KTD but also to partially evaluating the short-and long-term outcomes.Moreover,more attention should be paid to the two mutations(c.478 C>G;c.951 C>T)that may be associated with severeβ-KTD. 展开更多
关键词 Life-threatening symptoms Severeβ-ketothiolase deficiency Lesions outside of the basal ganglia Irreversible damage to the basal ganglia Magnetic resonance imaging New mutation Case report
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Diagnosis of Boron Deficiency in Green Dwarf Coconut Palm 被引量:1
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作者 Leandro Glaydson da Rocha Pinho Pedro Henrique Monnerat +2 位作者 Andre Assis Pires Marta Simone Mendonca Freitas Claudio Roberto Marciano 《Agricultural Sciences》 2015年第1期164-174,共11页
The diagnosis of boron deficiency in coconut palms has been hampered by lack of information about its distribution in the plant. Two experiments were conducted, one in a greenhouse to induce boron deficiency in dwarf ... The diagnosis of boron deficiency in coconut palms has been hampered by lack of information about its distribution in the plant. Two experiments were conducted, one in a greenhouse to induce boron deficiency in dwarf green coconut palms, and other in the field, in which the plants received doses of boric acid, B(OH)3. The objective was to verify symptoms of boron deficiency and boron content variation in canopy, leaves and folioles (or leaflets). Boron deficient plants led leaves and folioles to become deformed. The deficient and sufficient contents of boron varied significantly in the canopy, but did not vary in leaves. The boron content increased significantly from bottom to the apex of the folioles in both treatments. To survey the level of boron in the coconut palm, the ideal is, using samples taken from the youngest leaf, to calculate the relation between the boron content in the apex of the foliole and the content in the center or in the folioles bottom, with minimum values 2.2 or 2.7, respectively. 展开更多
关键词 symptomS Leaf Analysis deficiency Induction Boric Acid SAMPLES Cocos nucifera
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Nutrients Deficiency and Excess Phenomena of Cut Rose and Their Physiological Significances
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作者 Jin Xingzi Li Ming +1 位作者 Jin Muzi Yang Jin 《Plant Diseases and Pests》 CAS 2014年第4期20-25,共6页
On the basis of a brief introduction of essential major dements and trace dements for cut rose, the physiological effect and deficiency and excess phenomena of major elements including nitrogen, phosphorus, potassium,... On the basis of a brief introduction of essential major dements and trace dements for cut rose, the physiological effect and deficiency and excess phenomena of major elements including nitrogen, phosphorus, potassium, magnesium, calcium, sulfur and trace dements including zinc, molybdenum, boron, iron, manganese, copper were mainly described; the main factors influencing nutrients absorption of cut rose were summarized, in order to provide a reference for the reasonable fertilization of cut rese. 展开更多
关键词 Cut rose Physiological effect deficiency symptoms Excess phenomenon Influence factors
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Clinical study on fire needle acupuncture treating irregular menstruation with spleen deficiency syndrome
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作者 He-Ran Zhang Yue-Qiao Ren 《TMR Non-Drug Therapy》 2022年第2期1-5,共5页
Objective:To observe the clinical efficacy of fire needle acupuncture in treating irregular menstruation with spleen deficiency syndrome.Methods:60 patients with spleen deficiency-irregular menstruation were randomly ... Objective:To observe the clinical efficacy of fire needle acupuncture in treating irregular menstruation with spleen deficiency syndrome.Methods:60 patients with spleen deficiency-irregular menstruation were randomly divided into treatment group and control group of 30 each.In the treatment group,fire needle acupuncture was used to insert into Guanyuan,Qihai,Pishu,Sanyinjiao,Zusanli and Taibai points,while the filiform needle was used to needle the corresponding acupoints in the control group.After 8 weeks of treatment,menstrual cycle,menstrual period,menstrual volume,irregular menstrual symptom score and spleen deficiency symptom score were recorded.Results:Both treatments could effectively improve the menstrual cycle,menstrual period and menstrual volume,but there was no statistical significance between the two groups(P>0.05).Both treatments were effective in regulating the symptoms of menstruation,and fire needle acupuncture was better than filiform needle(P<0.05).Both treatments relieved the symptoms of spleen deficiency,and fire needle acupuncture was better than filiform needle(P<0.05).In terms of overall curative effect,the curative effect of fire needle acupuncture therapy was significantly better than filiform needle therapy,and the difference was statistically significant(P<0.05).Conclusion:Fire needle acupuncture therapy could effectively regulate menstrual volume of patients with irregular menstruation of spleen deficiency syndrome,and relieve the symptoms of traditional Chinese medicine. 展开更多
关键词 fire needle acupuncture irregular menstruation spleen deficiency syndrome symptoms of traditional Chinese medicine
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隔药灸脐法治疗肝郁脾虚型腹泻型肠易激综合征临床研究
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作者 马凤君 刘芳 +3 位作者 张巍 刘桐 李昕芮 马玉侠 《山东中医杂志》 2025年第1期66-71,84,共7页
目的:探讨隔药灸脐法治疗肝郁脾虚型腹泻型肠易激综合征(IBS-D)的临床疗效。方法:选取30例肝郁脾虚型IBS-D患者纳入隔药灸脐组,30例健康志愿者纳入正常对照组,隔药灸脐组患者持续进行2个月的隔药灸脐治疗,正常对照组不予任何干预。观察... 目的:探讨隔药灸脐法治疗肝郁脾虚型腹泻型肠易激综合征(IBS-D)的临床疗效。方法:选取30例肝郁脾虚型IBS-D患者纳入隔药灸脐组,30例健康志愿者纳入正常对照组,隔药灸脐组患者持续进行2个月的隔药灸脐治疗,正常对照组不予任何干预。观察隔药灸脐组患者治疗前后的IBS症状严重程度量表(IBSSSS)评分、临床疗效,以及两组纳入者的内脏敏感指数(VSI)量表评分和血清瞬时受体电位香草酸亚型1(TRPV1)、P物质(SP)、降钙素基因相关肽(CGRP)水平。结果:治疗后,隔药灸脐组患者的IBS-SSS量表各条目评分及总分均较治疗前降低,差异有统计学意义(P<0.01),该组的隔药灸脐治疗总有效率100%。入组时,隔药灸脐组的VSI量表评分高于正常对照组(P<0.01);治疗后,隔药灸脐组的VSI量表评分较入组时降低(P<0.01)。入组时,隔药灸脐组血清TRPV1、SP、CGRP水平均高于正常对照组(P<0.01);治疗后,隔药灸脐组血清TRPV1、SP、CGRP水平较入组时降低(P<0.01)。结论:隔药灸脐法可以改善肝郁脾虚型IBS-D患者的临床症状,降低患者内脏高敏性。 展开更多
关键词 腹泻型肠易激综合征 隔药灸脐 肝郁脾虚 肠易激综合征症状严重程度量表 内脏高敏性
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升清降浊方联合常规西药治疗老年帕金森病疗效及对患者非运动症状的影响
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作者 陈杨丽 赵彦青 王伟民 《陕西中医》 CAS 2025年第1期64-67,共4页
目的:探讨升清降浊方联合常规西药治疗老年帕金森病(气虚痰瘀证)疗效及对患者非运动症状的影响。方法:选取90例老年帕金森病患者,采用随机数表法将患者分为升清降浊组(n=45)和西药组(n=45),西药组患者采用常规西药治疗,升清降浊组采用... 目的:探讨升清降浊方联合常规西药治疗老年帕金森病(气虚痰瘀证)疗效及对患者非运动症状的影响。方法:选取90例老年帕金森病患者,采用随机数表法将患者分为升清降浊组(n=45)和西药组(n=45),西药组患者采用常规西药治疗,升清降浊组采用升清降浊方联合常规西药治疗,两组患者均持续治疗1个月。记录两组治疗前后中医证候评分、帕金森病症状[采用统一帕金森病评定量表(UPDRS)评估]、非运动症状[采用非运动症状量表(NMSS)评估]、生活质量[采用帕金森病生活质量评分量表(PDQ)评估]和不良反应[采用精神症状评定-不良反应量表(TESS)评估]。结果:治疗后,升清降浊组患者的中医证候评分较西药组低,差异有统计学意义(P<0.05);升清降浊组患者的UPDRS、NMSS和PDQ量表评分较西药组低,差异有统计学意义(P<0.05)。治疗过程中,升清降浊组患者TESS量表评分中自主神经症状的不良反应评分较西药组低,差异有统计学意义(P<0.05)。结论:升清降浊方联合常规西药治疗可以改善气虚痰瘀型老年帕金森病患者中医证候和非运动症状,提高患者生活质量,降低不良反应发生情况。 展开更多
关键词 老年帕金森病 升清降浊方 中医证候评分 气虚痰瘀证 非运动症状
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甲巯咪唑联合养阴平甲汤治疗阴虚火旺型甲状腺功能亢进症患者的效果
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作者 田露 裴瑞霞 +2 位作者 白小林 张婷 赵美云 《国际医药卫生导报》 2025年第4期578-581,共4页
目的探讨甲巯咪唑联合养阴平甲汤治疗阴虚火旺型甲状腺功能亢进症患者的效果。方法选取2022年2月至2024年2月西安市中医医院收治的90例阴虚火旺型甲状腺功能亢进患者进行随机对照试验。采用随机数字表法将其分为对照组和观察组,各45例... 目的探讨甲巯咪唑联合养阴平甲汤治疗阴虚火旺型甲状腺功能亢进症患者的效果。方法选取2022年2月至2024年2月西安市中医医院收治的90例阴虚火旺型甲状腺功能亢进患者进行随机对照试验。采用随机数字表法将其分为对照组和观察组,各45例。对照组男18例,女27例,年龄(54.69±5.38)岁。观察组男19例,女26例,年龄(54.78±5.26)岁。对照组予以甲巯咪唑治疗,观察组予以甲巯咪唑联合养阴平甲汤治疗。两组均治疗2个月。比较两组临床疗效、治疗前后中医症候积分、甲状腺功能[游离三碘甲状腺原氨酸(free triiodothyronine,FT3)、游离四碘甲状腺原氨酸(free thyroxine,FT4)、促甲状腺激素(thyroid stimulating hormone,TSH)]和不良反应发生情况。采用χ^(2)检验、t检验进行统计分析。结果观察组治疗总有效率高于对照组[93.33%(42/45)比77.78%(35/45)],差异有统计学意义(χ^(2)=4.406,P<0.05)。治疗后,观察组烘热多汗、烦躁易怒、倦怠乏力、心悸失眠得分均低于对照组[(1.36±0.14)分比(2.45±0.21)分、(1.21±0.12)分比(2.29±0.20)分、(1.12±0.11)分比(2.94±0.27)分、(1.34±0.15)分比(3.01±0.32)分],差异均有统计学意义(t=28.971、31.062、41.876、31.699,均P<0.05)。治疗后,观察组FT3、FT4水平均低于对照组[(7.46±1.59)pmol/L比(11.02±2.23)pmol/L、(26.54±2.76)pmol/L比(33.57±3.85)pmol/L],TSH水平高于对照组[(0.86±0.19)mIU/L比(0.41±0.10)mIU/L],差异均有统计学意义(t=8.720、9.955、14.059,均P<0.05)。观察组不良反应发生率低于对照组[4.44%(2/45)比20.00%(9/45)],差异有统计学意义(χ^(2)=5.075,P<0.05)。结论甲巯咪唑联合养阴平甲汤治疗阴虚火旺型甲状腺功能亢进症患者的效果优于单独使用甲巯咪唑,能改善患者临床症状,调节甲状腺功能指标,且安全性更高。 展开更多
关键词 甲状腺功能亢进症 甲巯咪唑 养阴平甲汤 阴虚火旺型 中医症候积分
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会厌逐瘀汤临床应用研究
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作者 刘媛媛 刘轶凡 宋咏梅 《山东中医药大学学报》 2025年第1期51-56,共6页
以会厌逐瘀汤为研究对象,检索现代临床研究文献,统计分析会厌逐瘀汤治疗的常见疾病及证候分布情况,并按照疾病、兼证、症状三种情况对加味药物进行分类,对会厌逐瘀汤的临床应用情况进行分析。研究发现会厌逐瘀汤加减可治疗咽喉部及全身... 以会厌逐瘀汤为研究对象,检索现代临床研究文献,统计分析会厌逐瘀汤治疗的常见疾病及证候分布情况,并按照疾病、兼证、症状三种情况对加味药物进行分类,对会厌逐瘀汤的临床应用情况进行分析。研究发现会厌逐瘀汤加减可治疗咽喉部及全身疾病31种,血瘀为咽喉部疾病的重要病机,并常兼有气虚、气滞、痰凝等证,其主要的加味药物有黄芪、党参、郁金、石菖蒲、木蝴蝶、射干等。研究还提示临床疾病治疗时应注重咽喉的重要性,部分疾病可以尝试从咽论治。 展开更多
关键词 会厌逐瘀汤 咽喉病 方-证-症 血瘀 气滞 气虚 痰凝
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Combined liver-kidney transplantation for rare diseases
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作者 Mladen Knotek Rafaela Novak +1 位作者 Alemka Jaklin-Kekez Anna Mrzljak 《World Journal of Hepatology》 CAS 2020年第10期722-737,共16页
Combined liver and kidney transplantation(CLKT)is indicated in patients with failure of both organs,or for the treatment of end-stage chronic kidney disease(ESKD)caused by a genetic defect in the liver.The aim of the ... Combined liver and kidney transplantation(CLKT)is indicated in patients with failure of both organs,or for the treatment of end-stage chronic kidney disease(ESKD)caused by a genetic defect in the liver.The aim of the present review is to provide the most up-to-date overview of the rare conditions as indications for CLKT.They are major indications for CLKT in children.However,in some of them(e.g.,atypical hemolytic uremic syndrome or primary hyperoxaluria),CLKT may be required in adults as well.Primary hyperoxaluria is divided into three types,of which type 1 and 2 lead to ESKD.CLKT has been proven effective in renal function replacement,at the same time preventing recurrence of the disease.Nephronophthisis is associated with liver fibrosis in 5%of cases and these patients are candidates for CLKT.In alpha 1-antitrypsin deficiency,hereditary C3 deficiency,lecithin cholesterol acyltransferase deficiency and glycogen storage diseases,glomerular or tubulointerstitial disease can lead to chronic kidney disease.Liver transplantation as a part of CLKT corrects underlying genetic and consequent metabolic abnormality.In atypical hemolytic uremic syndrome caused by mutations in the genes for factor H,successful CLKT has been reported in a small number of patients.However,for this indication,CLKT has been largely replaced by eculizumab,an anti-C5 antibody.CLKT has been well established to provide immune protection of the transplanted kidney against donor-specific antibodies against class I HLA,facilitating transplantation in a highly sensitized recipient. 展开更多
关键词 Combined liver-kidney transplantation Methylmalonic aciduria Hereditary complement C3 deficiency Glycogen storage diseases Homozygous protein C deficiency Primary hyperoxaluria Atypical hemolytic uremic syndrome SENSITIZATION Donorspecific antibodies
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浅谈颜红教授温阳法治疗抑郁症低动力症状
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作者 高雅 沈莉 +1 位作者 林锦 颜红 《中国中医药现代远程教育》 2024年第12期63-66,共4页
“低动力”为抑郁症的常见特征,表现为精力减退、疲劳感、反应迟缓、性欲减退等,严重影响患者的生活、工作、社交能力。作者随第七批全国老中医药专家学术经验继承老师、天津市名中医颜红教授学习,发现临床上此类症状可归为阳虚证,由于... “低动力”为抑郁症的常见特征,表现为精力减退、疲劳感、反应迟缓、性欲减退等,严重影响患者的生活、工作、社交能力。作者随第七批全国老中医药专家学术经验继承老师、天津市名中医颜红教授学习,发现临床上此类症状可归为阳虚证,由于患者长期七情内伤、思虑过度,使情志失遂,进而导致阳气不振、心神失养。治以温阳之法,振奋阳气,可有效改善抑郁症患者低动力症状,值得临床推广使用。 展开更多
关键词 郁证 抑郁症低动力症状 阳虚证 温阳法 颜红 名医经验
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加减柴胡温经汤治疗对围绝经期失眠(肝郁阴虚夹瘀型)患者中医症候积分、神经递质及炎症因子的影响
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作者 曹晓芳 冷锋 郑宁 《四川中医》 2024年第7期155-159,共5页
目的:探究加减柴胡温经汤治疗对围绝经期失眠(肝郁阴虚夹瘀型)患者中医症候积分、神经递质及炎症因子的影响。方法:于2021年12月~2022年12月本院收治的围绝经期失眠患者中选取102例作为研究对象,并按随机数字表法分成对照组(51例)和研究... 目的:探究加减柴胡温经汤治疗对围绝经期失眠(肝郁阴虚夹瘀型)患者中医症候积分、神经递质及炎症因子的影响。方法:于2021年12月~2022年12月本院收治的围绝经期失眠患者中选取102例作为研究对象,并按随机数字表法分成对照组(51例)和研究组(51例)。对照组给予舒乐安定治疗,研究组给予加减柴胡温经汤治疗,时长均为8周。比较两组疗效、中医症候(长期失眠、健忘、心烦易怒、肌肤甲错瘙痒、疲乏酸痛)积分、神经递质因子[β-内啡肽(β-EP)、神经肽Y(NPY)、5-羟色胺(5-HT)]水平、炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、白介素-6(IL-6)]水平、睡眠结构[总睡眠时间(TST)、睡眠潜伏期(SL)、睡眠效率(SE)、觉醒时间(AT)]和不良反应发生率的变化。结果:治疗8周后,研究组的总有效率为92.16%高于对照组的76.47%(P<0.05);两组的各项症候积分低于治疗前(P<0.05),且研究组低于对照组(P<0.05);两组NPY、β-EP、5-HT水平高于治疗前,IL-6、TNF-α、IL-1β水平低于治疗前,且研究组变化的幅度高于对照组(P<0.05);两组TST、SE高于治疗前,SL、AT均低于治疗前,且研究组变化的幅度高于对照组(P<0.05);两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论:加减柴胡温经汤治疗肝郁阴虚夹瘀型围绝经期失眠患者的效果显著,能有效改善中医症候,提高神经递质含量,降低炎症因子水平,优化睡眠结构。 展开更多
关键词 围绝经期失眠 肝郁阴虚夹瘀型 加减柴胡温经汤 中医症候积分 神经递质 炎症因子
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‘阳光玫瑰’葡萄9种缺素症的观察与分析 被引量:1
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作者 方啸宇 徐文清 +4 位作者 李少楠 任艳华 上官凌飞 陆爱华 房经贵 《南京农业大学学报》 CAS CSCD 北大核心 2024年第3期435-442,共8页
[目的]本文旨在通过观察‘阳光玫瑰’葡萄9种缺素表观差异并研究株高等生长指标以及叶绿素含量等生理指标,为及时进行营养诊断及指导田间施肥提供参考。[方法]以1年生‘阳光玫瑰’葡萄扦插苗为材料,采用大棚内珍珠岩盆栽方式,设置改良... [目的]本文旨在通过观察‘阳光玫瑰’葡萄9种缺素表观差异并研究株高等生长指标以及叶绿素含量等生理指标,为及时进行营养诊断及指导田间施肥提供参考。[方法]以1年生‘阳光玫瑰’葡萄扦插苗为材料,采用大棚内珍珠岩盆栽方式,设置改良霍格兰完全营养液(CK)和缺素(-N、-P、-K、-Ca、-Mg、-Fe、-B、-Zn、-Cu)营养液培养处理,分析各处理条件下植株的表观差异与生长生理指标。[结果]缺P、Mg和Zn时,‘阳光玫瑰’发生症状更早;缺B、Cu和Mg时,株高生长明显缓慢,并且症状发生剧烈,死亡率高。与对照相比,‘阳光玫瑰’缺Ca、缺B时叶片数量显著下降。缺素胁迫显著降低‘阳光玫瑰’叶片叶绿素含量,但对叶片含水量影响较小。葡萄对缺素胁迫的抗性与MDA含量和SOD活性总体呈正相关,即含量与活性越大,抗性越强。[结论]‘阳光玫瑰’对B和Mg元素的缺乏较敏感、耐性弱,对Zn元素的缺乏耐性较强。 展开更多
关键词 ‘阳光玫瑰’葡萄 营养液培养 缺素 表观 生长生理指标
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血管性认知障碍肾阳虚证症状辨识量表信效度检验
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作者 郭春艳 傅晨 +8 位作者 徐榛敏 王敏 张颖 侯小兵 李涛 牛焕敏 孙林娟 张允岭 陈宝鑫 《中国中医药信息杂志》 CAS CSCD 2024年第11期153-157,共5页
目的评价肾阳虚证症状辨识量表的可行性、信度及效度。方法使用前期制定的肾阳虚证症状辨识量表,于2020年9月-2022年9月对200例血管性认知障碍患者进行量表调查,通过回收率、完成率和完成时间分析量表可行性;通过重测信度、分半信度、... 目的评价肾阳虚证症状辨识量表的可行性、信度及效度。方法使用前期制定的肾阳虚证症状辨识量表,于2020年9月-2022年9月对200例血管性认知障碍患者进行量表调查,通过回收率、完成率和完成时间分析量表可行性;通过重测信度、分半信度、同质性信度分析量表信度;通过区分效度、结构效度分析量表效度。结果共发出量表200份,均全部配合并在20 min内完成及回收。信度分析结果显示,重测信度中量表阳虚维度为0.828,肾气虚维度为0.718;分半信度中斯皮尔曼相关系数为0.784;同质性信度中阳虚维度克朗巴赫系数为0.799,肾气虚维度克朗巴赫系数为0.670。效度分析结果显示,区分效度中肾阳虚证组与非肾阳虚证组阳虚维度、肾气虚维度得分和量表总得分差异有统计学意义(P<0.001);结构效度中KMO值为0.842,共提取到2个特征值均大于1的因子,累积方差百分比为58.227%。结论本研究中肾阳虚证症状辨识量表具有一定信效度,可较好地预测血管性认知障碍肾阳虚证,但效度相对较低,需要进一步修订后应用于临床。 展开更多
关键词 血管性认知障碍 肾阳虚证 肾阳虚证症状辨识量表 信度 效度
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加减柴胡温经汤辅助治疗肝郁阴虚夹瘀型失眠的疗效及对神经递质、情绪的影响 被引量:1
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作者 高娟 张则甫 《检验医学与临床》 CAS 2024年第2期247-250,256,共5页
目的探讨加减柴胡温经汤辅助治疗肝郁阴虚夹瘀型失眠患者的疗效及对神经递质、情绪的影响。方法选取2021年5月至2022年5月该院收治的94例肝郁阴虚夹瘀型失眠患者作为研究对象,采用随机数字表法分为常规组和试验组,每组各47例。常规组采... 目的探讨加减柴胡温经汤辅助治疗肝郁阴虚夹瘀型失眠患者的疗效及对神经递质、情绪的影响。方法选取2021年5月至2022年5月该院收治的94例肝郁阴虚夹瘀型失眠患者作为研究对象,采用随机数字表法分为常规组和试验组,每组各47例。常规组采用百乐眠胶囊治疗,试验组采用百乐眠胶囊联合加减柴胡温经汤治疗。比较两组临床疗效、治疗前后相关评分[汉密尔顿抑郁量表(HAMD)、匹兹堡睡眠质量指数(PSQI)、汉密尔顿焦虑量表(HAMA)]、中医证候积分、血清神经递质[5-羟色胺(5-HT)、神经肽(NPY)、去甲肾上腺素(NE)、P物质(SP)]水平、性激素[雌二醇(E 2)、黄体生成素(LH)、卵泡刺激素(FSH)]水平。结果试验组治疗后临床总有效率为97.87%,高于常规组的82.98%,差异有统计学意义(P<0.05);两组治疗后PSQI、HAMD及HAMA评分均明显低于治疗前,且试验组均明显低于常规组,差异均有统计学意义(P<0.05);试验组治疗后烦躁易怒、入睡困难、多梦易醒及情志抑郁积分均明显低于常规组,差异均有统计学意义(P<0.05);试验组治疗后NPY、5-HT水平均高于常规组,NE、SP水平均低于常规组,差异均有统计学意义(P<0.05);试验组治疗后FSH、LH水平均明显低于常规组,E 2水平明显高于常规组,差异均有统计学意义(P<0.05)。结论加减柴胡温经汤辅助治疗肝郁阴虚夹瘀型失眠可提高疗效,改善患者临床症状、神经递质及性激素水平,减轻其负面情绪,有助于患者恢复。 展开更多
关键词 加减柴胡温经汤 肝郁阴虚夹瘀型失眠 神经递质 情绪 临床症状
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HIV阳性患者个体化网络程序的可用性评价
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作者 金依霖 朱政 +7 位作者 胡天天 杨中方 余骏雯 何加敏 潘燕云 孙文秀 孙美艳 郭成桦 《护士进修杂志》 2024年第18期1982-1988,共7页
目的评价人类免疫缺陷病毒(human immunodeficiency virus,HIV)阳性患者症状网络个体化程序的可用性。方法于2023年12月-2024年2月选取上海市公共卫生临床中心艾滋病(acquired immunodeficiency syndrome,AIDS)自愿咨询门诊就诊的HIV感... 目的评价人类免疫缺陷病毒(human immunodeficiency virus,HIV)阳性患者症状网络个体化程序的可用性。方法于2023年12月-2024年2月选取上海市公共卫生临床中心艾滋病(acquired immunodeficiency syndrome,AIDS)自愿咨询门诊就诊的HIV感染者、中心个案管理师等为研究对象。并基于“以用户为中心的理念”,对HIV患者个体化网络程序依次进行简捷形成性可用性评价、全面形成性可用性评价以及总结性可用性评价,收集量性及质性数据。结果研究共纳入22位研究对象,完成了三阶段的可用性评价,对所收集的质性资料编码归类后,形成了4个主题,对于评价过程中发现的部分问题及时进行了修正。结论该程序的功能基本符合设计者的要求,满足用户期望,不存在明显的可用性问题。为后续程序改进、个性化患者症状管理方案设计及临床推广打下基础。 展开更多
关键词 人类免疫缺陷病毒 艾滋病 可用性评价 症状网络 个体化网络 移动医疗程序
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基于复杂系统建模方法的慢性胃炎常见证型主症特征选择研究
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作者 郭本琼 刘怡 +3 位作者 徐玮斐 刘晏 颜建军 刘国萍 《广州中医药大学学报》 CAS 2024年第12期3321-3330,共10页
【目的】应用复杂系统建模方法,探讨慢性胃炎常见证型的主症特征,为慢性胃炎中医证候诊断的客观化研究提供思路。【方法】通过综合运用随机森林、互信息、粗糙集、近邻传播聚类、判别分析等方法,综合分析慢性胃炎常见证型如湿浊中阻证... 【目的】应用复杂系统建模方法,探讨慢性胃炎常见证型的主症特征,为慢性胃炎中医证候诊断的客观化研究提供思路。【方法】通过综合运用随机森林、互信息、粗糙集、近邻传播聚类、判别分析等方法,综合分析慢性胃炎常见证型如湿浊中阻证、脾胃气虚证、脾胃虚寒证、肝郁气滞证、肝胃郁热证的症状群,挖掘症状和证型之间、症状与症状之间的关系。通过判别分析交互验证法与受试者工作特征曲线下面积(AUC)值对慢性胃炎主症的诊断效果进行评价。【结果】湿浊中阻证的正相关特异性症状为苔腻、齿痕舌、苔厚、胖大舌,负相关鉴别症状为舌色红、苔薄、苔黄(预测准确率为79.2%,AUC值为0.868);脾胃气虚证的正相关特异性症状为乏力、苔白、齿痕舌、唇色淡白、便溏,负相关鉴别症状为苔腻、舌色红(预测准确率为75.5%,AUC值为0.830);脾胃虚寒证的正相关特异性症状为肢冷/手足欠温、胃脘喜暖、苔薄,未见负相关鉴别症状(预测准确率为79.2%,AUC值为0.836);肝郁气滞证的正相关特异性症状为因情绪而加重、胁胀或痛、嗳气,负相关鉴别症状为乏力、苔腻(预测准确率为74.1%,AUC值为0.818);肝胃郁热证的正相关特异性症状为舌色红、胁胀或痛、唇色红,负相关鉴别症状为苔腻、苔白、苔厚(预测准确率为79.9%,AUC值为0.845)。慢性胃炎常见证候中正相关特异性症状病位要素主要涉及脾、胃、肝,病性要素主要涉及湿浊、气虚、血虚、寒湿、阳虚、气滞、热。【结论】通过综合运用复杂系统方法筛选得到的慢性胃炎常见证型主症特征与中医理论、临床实践、既往诊断标准基本一致。舌象、唇象特征在主症中的占比最大,提示舌诊、唇诊对于慢性胃炎中医证型的诊断具有重要意义。 展开更多
关键词 慢性胃炎 湿浊中阻证 脾胃气虚证 脾胃虚寒证 肝郁气滞证 肝胃郁热证 主症 舌象 唇象
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基于LASSO回归的心脏神经官能症刚虚证(肝肾阴亏、肝阳上亢证)关联因素筛选及诊断模型构建
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作者 王瑞婷 杨曜嘉 +5 位作者 张慧 原晨 柳红良 李娅 王韵涵 赵鹏 《中医药导报》 2024年第7期71-76,共6页
目的:利用LASSO回归联合Nomogram构建心脏神经官能症刚虚证(肝肾阴亏、肝阳上亢证)的诊断模型。方法:采用单中心前瞻性研究,收集141例心脏神经官能症患者的临床资料,纳入分析变量包括年龄、民族、婚姻、教育程度、脑力/体力工作、体质... 目的:利用LASSO回归联合Nomogram构建心脏神经官能症刚虚证(肝肾阴亏、肝阳上亢证)的诊断模型。方法:采用单中心前瞻性研究,收集141例心脏神经官能症患者的临床资料,纳入分析变量包括年龄、民族、婚姻、教育程度、脑力/体力工作、体质量指数(BMI)、中医症状、中医五态人格量表各因子得分、汉密尔顿焦虑量表-14项、汉密尔顿抑郁量表-24项、症状自测评量表各因子均分。通过LASSO回归筛选与刚虚证诊断显著相关的影响因素,纳入二元多因素Logistic回归分析构建诊断模型,并对模型预测区分度及校准度评价,利用10重交叉验证进行内部验证,最后对模型进行Nomogram可视化,并根据ROC曲线确定诊断阈值。结果:共纳入刚虚证患者70例,非刚虚证患者71例。LASSO回归筛选出与刚虚证诊断相关性最显著的5个变量为女性、年龄、疲乏无力、善嗳气、五态人格中少阳积分。模型AUC为0.85,H-L检验为2.94(P=0.9824),提示模型区分度及校准度较好,10重交叉内部验证结果提示AUC为0.82。结论:LASSO回归联合Nomogram构建的诊断模型可协助诊断心脏神经官能症刚虚证,但研究结果的准确性尚待大样本临床研究进一步验证。 展开更多
关键词 心脏神经官能症 刚虚证 刚柔辨证 临床诊断模型 LASSO回归 列线图
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