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Effects of TCM Nursing Based on Syndrome Differentiation on Pulmonary Function and Quality of Life in Patients with Acute Exacerbation of COPD
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作者 Xiaolan FANG Ran MO +1 位作者 Yuanhui JIANG Yaonan DU 《Medicinal Plant》 CAS 2023年第4期77-79,共3页
[Objectives] To investigate the effects of TCM nursing based on syndrome differentiation on pulmonary function and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).... [Objectives] To investigate the effects of TCM nursing based on syndrome differentiation on pulmonary function and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). [Methods] A total of 92 patients with AECOPD who came to Nanchong Chinese Medicine Hospital from March 2022 to February 2023 were selected for the study, and the intervention group (TCM nursing based on syndrome differentiation, 46 cases) and the conventional group (basic nursing, 46 cases) were selected for the study, and the pulmonary function and quality of life of the two groups were compared. [Results] Before nursing, there was no significant difference in levels of forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and percentage of forced expiratory volume in one second to forced vital capacity (FEV1/FVC) between the intervention group and conventional group ( P >0.05). After 3 months of nursing, the levels of FVC, FEV1 and FEV1/FVC in the intervention group were higher than those in the conventional group ( P <0.05). Before nursing, there was no significant difference in the scores of health, emotion and social functions between the two groups ( P >0.05). At three months of nursing, the scores of health, emotion, and social functions in the intervention group were higher than those in the conventional group ( P <0.05). [Conclusions] The implementation of TCM nursing based on syndrome differentiation in patients with AECOPD can effectively improve the pulmonary function and quality of life of patients, and has significant clinical implementation value. 展开更多
关键词 Chronic obstructive pulmonary disease(COPD) TCM nursing based on syndrome differentiation Pulmonary function Quality of life
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The Comparative Study on Two Models of Syndrome Differentiation of the Hand, Foot and Mouth Disease: An Investigation Analysis of the Signs and Symptoms on 2325 Cases 被引量:1
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作者 Fan Nie Ke Hong +6 位作者 Hui-juan Li Xiu-hui Li Shuang-jie Li Wei Zhang Qing-jing Zhu Lu-kun Zhang Guang Nie 《国际感染病学(电子版)》 CAS 2014年第1期22-30,共9页
Objective To realize the characteristics of "zheng" differentiation-treatment for hand, foot and mouth disease(HFMD), a new methodology of syndrome differentiation for different stages of HFMD has been explo... Objective To realize the characteristics of "zheng" differentiation-treatment for hand, foot and mouth disease(HFMD), a new methodology of syndrome differentiation for different stages of HFMD has been explored. Methods Total of 2 325 cases with HFMD were recorded by distributing them into exterior syndrome stage, interior syndrome stage, severe syndrome stage and recovered syndrome stage, respectively, and the main symptoms and subsidiary symptoms of different stages of HFMD have been observed. The major and minor pathogenesis of HFMD in different stages were obtained, and compared with the "2010 Guideline for the Diagnosis and Treatment of HFMD". Results It was found that the major pathogenesis of exterior stage was defined as "the invation of the wenevil to the defender of the body with the collaterals got involved ", and the minor as "qi deficiency"; in interior stage, "the fury of Gan-Yang" was the main pathogenesis, and "qi in chaos and qi deficiency" was the minor; in severe syndrome stage, "the damage of heart, liver and lung" was the main pathogenesis, and "qi in chaos" was the minor; and the pathogenesis of recovered stage was "qi-yin deficiency". Compared with the "2010 Guideline for the Diagnosis and Treatment of HFMD", it showed that "the obstruction of the fei-pi qi by the mixture of shi-re evil" and "the mixture of shi-re" in vivo was quite difficult to be explained in completely different context in the general situation; in the severe stage, the TCM clinical characteristics of syndrome differentiation might lose; in the early acute severe cases, the phenomenon that xin-yang and fei-qi almost ran out was difficult to be observed, then, the line between the severe and the acute severe became vague.Conclusions The theory of syndrome differentiation by stages of HFMD was reasonable in the actual situation of clinical description on HFMD which was expected to be further tested and widely applied in the "zheng" differentiation-treatment of HFMD in the future. 展开更多
关键词 Hand foot and mouth disease(HFMD) syndrome differentiation in classification syndromes differentiation by types syndrome factors
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Research Survey of Animal Model of Hepatic Fibro-sis Integrated with Western Medicine Diseases and Traditional Chinese Medicine^TCM~)Syndrome 被引量:1
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作者 Peng Yue Yao Le +3 位作者 Zhao Tiejian Duan Xuelin Wei Yanfei Li Guiyu 《Animal Husbandry and Feed Science》 CAS 2017年第1期19-23,36,共6页
Although the animal models of hepatic fibrosis developed by former researchers have pathological changes of hepatic fibrosis, they do not include charac- teristics of important TCM syndromes such as stagnation of qi, ... Although the animal models of hepatic fibrosis developed by former researchers have pathological changes of hepatic fibrosis, they do not include charac- teristics of important TCM syndromes such as stagnation of qi, deficiency of qi, liver depression, phlegm-dampness and blood stasis because of single-factor model- ing. Animal models of hepatic fibrosis and animal models integrated disease and syndrome were reviewed, and several new types of integrated disease and syndrome animal models constructed by multiple-factor modeling method were evaluated, under the guidance of etiological theory of TCM. This kind of hepatic fibrosis model animals has dual characteristics of disease and syndrome. It is consistent with pathological characteristics of hepatic fibrosis in western medicine when replicating the basic characteristics accorded with TCM syndrome. Thus, the pathogenesis and pathogenic process of clinical disease and syndrome formation is simulated more ac- curately, providing a new platform and pathway for studying hepatic fibrosis disease with integrated traditional Chinese and western medicine. 展开更多
关键词 Chinese traditional medicine Combination of disease and syndrome Animal model
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HOW TO MASTER THE DIFFERENTIATION OF SYNDROMES AND THE SELECTION OF ACUPOINTS QUICKLY
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作者 Zhuang JiaxiuInstitute of Acupuncture and Moxibustion, China Academy of TCM, Beijing 100700, China 《World Journal of Acupuncture-Moxibustion》 1994年第1期53-56,共4页
Differentiation of syndromes can be done by three steps:First to differentiate thenature of disease,second to differentiate the location of disease,third to analyse comprehensively thenature and location of disease.De... Differentiation of syndromes can be done by three steps:First to differentiate thenature of disease,second to differentiate the location of disease,third to analyse comprehensively thenature and location of disease.Depend on complete differentiation of syndromes,the acupoints are selected.Three cases are analysed to explain how to dominate preceding contents. 展开更多
关键词 differentiation of syndromeS SELECTION of ACUPOINTS Nature of disease Location of disease
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ACUPUNCTURE TREATMENT ON 40 CASES OF IRRITABLE COLON SYNDROME ACCORDING TO DIFFERENTIATION OF SYMPTOMS AND SIGNS
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作者 Fu Huaidan, Cai GuoweiDepartment of Acupuncture and Moxibustian, Union Hospital Affiliated to Tongji Medical University, Wuhan 430022, China 《World Journal of Acupuncture-Moxibustion》 1994年第4期26-29,共4页
Irritable intestinal tract syndrome was classified and treated with acupuncture according to differentiation of symptoms and signs.Of the 40 cases treated,28 were cured,11 improved,and 6 ineffective.The total effectiv... Irritable intestinal tract syndrome was classified and treated with acupuncture according to differentiation of symptoms and signs.Of the 40 cases treated,28 were cured,11 improved,and 6 ineffective.The total effective rate was 85%.The syndrome was classified into fourtypes:weakness of the spleen and stomach,disharmony of the liver spleen,Yang deficiency ofthe spleen and kidney,and retention of dampness and heat.There was no statistically significant difference in therapeutic effects among the four types of syndromes.However,the curative effect in theacupuncture group was better than that in the medication group,and the difference was of statisticalsignificance. 展开更多
关键词 COLONIC diseaseS ACUPUNCTURE differentiation of syndrome
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Can TCM Treatment be Performed on the Basis of Differential Diagnosis of the Diseases Instead of the Syndromes?
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作者 林宗广 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第3期236-236,共1页
Great advances have been achieved in the integration of western and traditional Chinese medicine (TCM).More and more TCM physicians in their practice accept the term 'differential diagnosis of the diseases' in... Great advances have been achieved in the integration of western and traditional Chinese medicine (TCM).More and more TCM physicians in their practice accept the term 'differential diagnosis of the diseases' instead of the syndromes since western medicine has been introduced into the TCM circle. 展开更多
关键词 Diagnosis Differential Medicine Chinese Traditional APPENDICITIS disease Drugs Chinese Herbal Humans Liver Abscess PHYTOTHERAPY syndrome
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A Validated Model for the Imaging Diagnosis of Cystic Lung Disease
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作者 Wallace T. Miller Karen C. Patterson +22 位作者 Shweta Sood James E. Schmitt Arshad A. Wani Robert Borden Maya Galperin-Aisenberg Mary K. Porteus Michelle L. Hershman Michael Hewitt Jennifer Levy Victor D. Babatunde Tetiana Glushko Timothy J. Niesen Sergey Leshchinskiy Karine Sahakyan Keyur Desai Jennifer A. Gillman Sandeep Reddy Michael Shriver Nathaniel B. Linna Abass M. Noor Aysenur Buz Matthew E. Biron Scott Simpson 《Open Journal of Radiology》 2023年第1期42-57,共16页
Rationale and Objectives: Cystic lung disease may be accurately diagnosed by imaging interpretation of specialist radiologists, without other information. We hypothesized that with minimal training non-specialists cou... Rationale and Objectives: Cystic lung disease may be accurately diagnosed by imaging interpretation of specialist radiologists, without other information. We hypothesized that with minimal training non-specialists could perform similarly to specialist physicians in the diagnosis of cystic lung disease. Methods: 72 cystic lung disease cases and 25 cystic lung disease mimics were obtained from three sources: 1) a prospective acquired diffuse lung disease registry, 2) a retrospective search of medical records and 3) teaching files. Cases were anonymized, randomized and interpreted by 7 diffuse lung disease specialists and 15 non-specialist radiologists and pulmonologists. Clinical information other than age and sex was not provided. Prior to interpretation, non-specialists viewed a short PDF training document explaining cystic lung disease interpretation. Results: Correct first choice diagnosis of 85%-88% may be achieved by high-performing specialist readers and 71%-80% by non-specialists and lower-performing specialists, with mean accuracies in the diagnosis of LAM (91%, p Conclusion: With specific but limited training, non-specialist physicians can diagnose cystic lung diseases from CT appearance alone with similar accuracy to specialists, correctly identifying approximately 75% of cases. 展开更多
关键词 LYMPHANGIOLEIOMYOMATOSIS HISTIOCYTOSIS Langerhans-Cell Idiopathic Interstitial Pneumonias Birt-Hogg-Dube syndrome Lung diseases INTERSTITIAL DIAGNOSES Differential
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Long-term Effect of TCM Decoctions in Treatment of Nephrotic Syndrome 被引量:1
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作者 魏连波 叶任高 +3 位作者 栾图 吕瑞和 陈保田 王友京 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第2期83-86,共4页
Fifty-seven cases of nephrotic syndrome were treated with TCM decoctions as accessory treatment for prednisone and cyclophosphamide, and the effects were observed in a follow-up period of 5-15 years. The long-term com... Fifty-seven cases of nephrotic syndrome were treated with TCM decoctions as accessory treatment for prednisone and cyclophosphamide, and the effects were observed in a follow-up period of 5-15 years. The long-term complete remission rate of 68.4% and recurrence rate of 26.3% in the treatment group were respectively higher and lower than those in the control group (P 展开更多
关键词 PHYTOTHERAPY ADOLESCENT ADULT CYCLOPHOSPHAMIDE Diagnosis Differential Drug Combinations Drug Therapy Combination Drugs Chinese Herbal Female Follow-Up Studies Humans Male Medicine Chinese Traditional Middle Aged Nephrotic syndrome PREDNISONE
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Prof. Zhou Xuewen's Experience in Treating Superior Mesenteric Artery Syndrome
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作者 姚岚 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第4期261-263,共3页
Prof. Zhou Xuewen (周学文), a veteran TCM doctor,is an expert in treating miscellaneous internaldiseases. I have the honor to follow him and havebenefited from his teaching. The following is hisexperience in treating ... Prof. Zhou Xuewen (周学文), a veteran TCM doctor,is an expert in treating miscellaneous internaldiseases. I have the honor to follow him and havebenefited from his teaching. The following is hisexperience in treating superior mesenteric arterysyndrome that I would like to introduce below. 展开更多
关键词 PHYTOTHERAPY ADULT Diagnosis Differential Drug Combinations Drugs Chinese Herbal Female Humans Medicine Chinese Traditional Superior Mesenteric Artery syndrome
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Differentiating and Treating Gynecological Diseases based on the Theory of Collateral Diseases
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作者 XUE Bing REN Jie +3 位作者 YAN Ying WU Lin-ling HA Hong ZHANG Han 《World Journal of Integrated Traditional and Western Medicine》 2020年第10期28-37,共10页
The collateral disease theory is a unique component of the theoretical system of traditional Chinese medicine(TCM),which is currently applied to all kinds of diseases related to the collaterals.With the in-depth study... The collateral disease theory is a unique component of the theoretical system of traditional Chinese medicine(TCM),which is currently applied to all kinds of diseases related to the collaterals.With the in-depth study of collaterals theory by many practitioners,its advantages in differentiating and treating gynecological diseases are gradually embodied.Based on the theory of collaterals disease,we discussed the pathogenesis,syndrome differentiation and treatment of gynecological diseases,concluded that the deficient collaterals under nourishment and the stagnant and blocked uterine collateral are the important pathogenesis of gynecological illness.Then we pointed out that invigorating the spleen and tonifying the kidney,and unblocking collateral and dissipating stasis are important treatment methods.We discussed the application of collateral disease theory in Tianjin HA's gynecology,and provided certain theoretical basis and clinical reference for the treatment of gynecologic diseases. 展开更多
关键词 Collateral disease theory Gynecological diseases Etiology and pathogenesis syndrome differentiation treatment Tianjin HA's gynecology
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Risk factors of postoperative cerebral hyperperfusion syndrome and its relationship with clinical prognosis in adult patients with moyamoya disease 被引量:3
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作者 Zhiyong Shi Lingyun Wu +3 位作者 Yi Wang Huasheng Zhang Yongbo Yang Chunhua Hang 《Chinese Neurosurgical Journal》 CAS CSCD 2023年第3期190-198,共9页
Background To investigate the incidence,risk factors,and clinical prognosis of cerebral hyperperfusion syndrome(CHS)after superficial temporal artery-middle cerebral artery anastomosis combined with encephalo-duro-art... Background To investigate the incidence,risk factors,and clinical prognosis of cerebral hyperperfusion syndrome(CHS)after superficial temporal artery-middle cerebral artery anastomosis combined with encephalo-duro-arterio-synangiosis(STA-MCA/EDAS)in adult patients with moyamoya disease(MMD).Methods The clinical data of 160 adult patients with MMD treated by STA-MCA/EDAS from January 2016 to January 2017 were retrospectively analyzed.According to CHS diagnosis,MMD patients were divided into CHS and non-CHS group.Univariate and multivariate analysis of risk factors and Kaplan-Meier curve of stroke-free survival for CHS were performed.Results A total of 12 patients(7.5%)developed postoperative CHS,of which 4 patients(2.5%)presented with cerebral hemorrhage.Univariate and multivariate analysis showed moyamoya vessel on the surgical hemisphere(OR=3.04,95%CI=1.02-9.03,P=0.046)and left operated hemisphere(OR=5.16,95%CI=1.09-21.34,P=0.041)were independent risk factors for CHS.The other variables,such as age,gender,presentation,hypertension,diabetes,smoking,mean mRS score on admission,modified Suzuki stage and pre-infarction stage on surgical hemisphere,and bypass patency,had no association with postoperative CHS(P>0.05).At final follow-up with average 38 months,there were 18 out of 133 patients(13.5%,4.91%per person year)presented with newly developed complications.There was no significant difference between newly developed complications,mean mRS scores,and Kaplan-Meier curve of stroke-free survival in patients with and without CHS(P>0.05).Conclusion The concentration of moyamoya vessels and left operated hemisphere was independent risk factors for CHS,which could not affect the clinical prognosis if treated timely and properly.The current study offers a new perspective of moyamoya vessels and supporting data for choosing MMD candidates on cerebral revascularization. 展开更多
关键词 Moyamoya disease combined cerebral revascularization Cerebral hyperperfusion syndrome Risk factors Clinical prognosis
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Professor Chen Xianhai's experience of herb pairs in the treatment of pulmonary diseases
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作者 Jia-Lu Ma Qing Li +1 位作者 Xue Zhu Xian-Hai Chen 《Journal of Hainan Medical University》 2021年第12期49-50,共2页
According to the theory of traditional Chinese medicine,based on the four properties and five flavors of traditional Chinese medicines,the lifting and lowering theory and channel tropism,Professor Chen combined with t... According to the theory of traditional Chinese medicine,based on the four properties and five flavors of traditional Chinese medicines,the lifting and lowering theory and channel tropism,Professor Chen combined with the theory of traditional Chinese medicine and constitution identification to prescribe for patients and used herb pairs to treat many kinds of pulmonary diseases.And he has achieved good clinical effect by"treatment methods selection according to syndromes".His experience in medication and compatibility mechanism are worthy of further exploration and promotion by scholars. 展开更多
关键词 Herb pairs Pulmonary diseases syndrome differentiation and treatment EXPERIENCE CHEN Xian-hai
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Combined liver-kidney transplantation for rare diseases
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作者 Mladen Knotek Rafaela Novak +1 位作者 Alemka Jaklin-Kekez Anna Mrzljak 《World Journal of Hepatology》 CAS 2020年第10期722-737,共16页
Combined liver and kidney transplantation(CLKT)is indicated in patients with failure of both organs,or for the treatment of end-stage chronic kidney disease(ESKD)caused by a genetic defect in the liver.The aim of the ... Combined liver and kidney transplantation(CLKT)is indicated in patients with failure of both organs,or for the treatment of end-stage chronic kidney disease(ESKD)caused by a genetic defect in the liver.The aim of the present review is to provide the most up-to-date overview of the rare conditions as indications for CLKT.They are major indications for CLKT in children.However,in some of them(e.g.,atypical hemolytic uremic syndrome or primary hyperoxaluria),CLKT may be required in adults as well.Primary hyperoxaluria is divided into three types,of which type 1 and 2 lead to ESKD.CLKT has been proven effective in renal function replacement,at the same time preventing recurrence of the disease.Nephronophthisis is associated with liver fibrosis in 5%of cases and these patients are candidates for CLKT.In alpha 1-antitrypsin deficiency,hereditary C3 deficiency,lecithin cholesterol acyltransferase deficiency and glycogen storage diseases,glomerular or tubulointerstitial disease can lead to chronic kidney disease.Liver transplantation as a part of CLKT corrects underlying genetic and consequent metabolic abnormality.In atypical hemolytic uremic syndrome caused by mutations in the genes for factor H,successful CLKT has been reported in a small number of patients.However,for this indication,CLKT has been largely replaced by eculizumab,an anti-C5 antibody.CLKT has been well established to provide immune protection of the transplanted kidney against donor-specific antibodies against class I HLA,facilitating transplantation in a highly sensitized recipient. 展开更多
关键词 combined liver-kidney transplantation Methylmalonic aciduria Hereditary complement C3 deficiency Glycogen storage diseases Homozygous protein C deficiency Primary hyperoxaluria Atypical hemolytic uremic syndrome SENSITIZATION Donorspecific antibodies
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Exploration on Relationship between Syndrome Differentiation ofPhlegm Stasis Syndrome and Serum Lipoprotein EleotrophoretogramIn Patients of Senile Coronary Heart Disease
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作者 梁东辉 +4 位作者 曾昭龙 李小敏 陈允钦 钱学贤 尹炳生 《Chinese Journal of Integrative Medicine》 SCIE CAS 1999年第2期147-147,共1页
关键词 PSS Exploration on Relationship between syndrome differentiation ofPhlegm Stasis syndrome and Serum Lipoprotein EleotrophoretogramIn Patients of Senile Coronary Heart disease
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Implementation status quo of traditional Chinese medicine nursing program for advantaged diseases
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作者 Chun-Hua Zhang Chun-Guang Yu +3 位作者 Hui-Xin Ding Pei-Yao Li Wen-Wen Zhao Ling Wang 《TMR Integrative Nursing》 2019年第2期61-67,共7页
With the promulgation of the traditional Chinese medicine(TCM)nursing program for advantaged diseases,its application in the clinic has drawn wide attention.TCM nursing program can actively promote the clinical develo... With the promulgation of the traditional Chinese medicine(TCM)nursing program for advantaged diseases,its application in the clinic has drawn wide attention.TCM nursing program can actively promote the clinical development of TCM syndrome differentiation and nursing.This article introduces the implementation status quo of the TCM nursing program for advantaged diseases in clinical practice,summarize the existing problems in the implementation and put forward measures to promote its perfection.Finally,the article discusses and looks forward to the TCM nursing program for advantaged diseases.Provide theoretical basis and reference for medical workers to effectively promote the application and implementation of TCM nursing programs for advantaged disease. 展开更多
关键词 Advantaged diseases Traditional Chinese medicine nursing program syndrome differentiation and nursing Implementation status quo
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基于治未病理论灸药同治对实体恶性肿瘤化疗患者骨髓抑制的预防作用 被引量:2
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作者 李磊 周锦 +5 位作者 余涛 张豪荣 陈辰 余长艳 宋海斌 朱琼洁 《世界中医药》 CAS 北大核心 2024年第3期368-372,共5页
目的:基于治未病理论探讨灸药同治对实体恶性肿瘤化疗患者骨髓抑制的预防作用。方法:选取2019年1月至2022年1月于武汉科技大学附属武汉亚心总医院接受治疗的实体恶性肿瘤化疗患者120例作为研究对象,采用随机数字表法分为对照组和观察组... 目的:基于治未病理论探讨灸药同治对实体恶性肿瘤化疗患者骨髓抑制的预防作用。方法:选取2019年1月至2022年1月于武汉科技大学附属武汉亚心总医院接受治疗的实体恶性肿瘤化疗患者120例作为研究对象,采用随机数字表法分为对照组和观察组,每组60例。对照组常规接受化疗,观察组化疗前连续3 d给予灸药同治(艾灸+加味八珍汤)。比较治疗前、化疗后7 d 2组患者中医证候积分、血常规[血红蛋白(Hb)、白细胞计数(WBC)、血小板计数(PLT)、中性粒细胞计数(NEUT)]、生命质量[卡诺夫斯凯计分(KPS)、中国癌症患者生命质量(QOL_(2))调查问卷],比较化疗后7 d 2组患者骨髓抑制情况[发生率、严重程度、重组人粒细胞集落刺激因子(rhG-CSF)使用情况]。结果:化疗后7 d,2组患者中医证候积分升高,但观察组低于对照组(P<0.05);Hb、WBC、PLT、NEUT、KPS评分及QOL_(2)评分降低,但观察组高于对照组(均P<0.05);观察组骨髓抑制发生率、rhG-CSF使用率低于对照组,0、Ⅰ度比例高于对照组(均P<0.05)。结论:基于治未病理论,灸药同治能够改善实体恶性肿瘤化疗患者临床症状及血常规,提高患者生命质量,减少骨髓抑制的发生。 展开更多
关键词 恶性肿瘤 治未病理论 灸药同治 化疗 骨髓抑制 中医证候积分 血常规 生命质量
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论基于“病、证、征结合”方剂的主治表述 被引量:1
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作者 杨婷 陈少丽 都广礼 《上海中医药杂志》 CSCD 2024年第4期45-48,共4页
目前对方剂主治的规范性研究较少,通过对方剂主治源流的梳理并分析《方剂学》教材中方剂主治描述中存在的问题,提出“病、证、征结合”3个层次的方剂主治描述规范,从而有利于临证依法用方、规范教材和规范方剂的科学研究。
关键词 方剂 主治 辨病论治 辨证论治 中医药疗法
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基于数据挖掘方法探讨脾胃名家李德新教授临床诊疗虚劳疾病规律 被引量:1
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作者 翁姣 王彩霞 《辽宁中医药大学学报》 CAS 2024年第6期47-51,共5页
目的基于数据挖掘技术探讨李德新教授治疗虚劳疾病的用药规律。方法收集、整理李德新教授临床诊疗虚劳疾病的病例,运用频数、频率、聚类分析、关联分析等方法对病例中的证型诊断和处方用药进行统计分析和数据挖掘,归纳整理后对医案数据... 目的基于数据挖掘技术探讨李德新教授治疗虚劳疾病的用药规律。方法收集、整理李德新教授临床诊疗虚劳疾病的病例,运用频数、频率、聚类分析、关联分析等方法对病例中的证型诊断和处方用药进行统计分析和数据挖掘,归纳整理后对医案数据进行科学计算。结果共纳入治疗标准医案虚劳741例,挖掘出与疾病相对应的高频症状、高频证型、高频中药,并对中药进行聚类分析得到有效配伍,同时进行症状、证型与相关中药的关联分析。结论利用数据挖掘技术,可初步揭示李德新教授临床诊疗虚劳疾病的规律,从虚劳论治,培补虚劳对于疾病的治疗具有重要意义,有助于更好地传承李德新教授的学术思想,具有较高的临床参考和学习价值。 展开更多
关键词 李德新 虚劳 证治规律 数据挖掘 数据分析
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孙桂芝病证结合辨证在肿瘤治疗中的应用
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作者 刘声 吴洁 +1 位作者 王逊 胡凤山 《世界中医药》 CAS 北大核心 2024年第9期1307-1311,共5页
病证结合是孙桂芝教授治疗肿瘤病学术思想的重要组成部分,把辨证与辨病有机地结合起来,进行综合诊治,既照顾到整体,又注意到局部;辨证为先还是辨病为先在临床诊疗中要根据实际情况而定,二者互补。特别是现代科学技术的发展弥补了中医诊... 病证结合是孙桂芝教授治疗肿瘤病学术思想的重要组成部分,把辨证与辨病有机地结合起来,进行综合诊治,既照顾到整体,又注意到局部;辨证为先还是辨病为先在临床诊疗中要根据实际情况而定,二者互补。特别是现代科学技术的发展弥补了中医诊疗方面的不足,辨病治疗成为中医治疗学的重要部分。孙桂芝教授临证始终强调辨证与辨病紧密相连,中西手段并用,诊断疾病现代仪器和中医四诊联合,治疗上病证相参结合,攻补兼施,标本兼治,既要兼顾全局,也要重视细节。 展开更多
关键词 肿瘤 @孙桂芝 病证结合 辨证 辨病 学术思想 临床实践 衷中参西
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基于数据挖掘的胆石症动物模型特点及应用分析
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作者 王琳琳 朱正望 +2 位作者 赵静涵 苗明三 朱平生 《中药新药与临床药理》 CAS CSCD 北大核心 2024年第10期1621-1627,共7页
目的对现有胆石症动物模型进行整理归纳,探索可更好反映中西医临床病证特点,满足中医药临床与基础研究发展需要的动物模型。方法检索中国知网、万方、维普、SinoMed、PubMed等数据库,对国内外胆石症相关实验研究的动物模型进行搜集和整... 目的对现有胆石症动物模型进行整理归纳,探索可更好反映中西医临床病证特点,满足中医药临床与基础研究发展需要的动物模型。方法检索中国知网、万方、维普、SinoMed、PubMed等数据库,对国内外胆石症相关实验研究的动物模型进行搜集和整理,对模型的动物种类、造模方法、造模周期、检测指标和阳性药等数据进行统计和分析。结果纳入的128篇文献中,胆石症模型的动物种类以豚鼠、家兔和C57BL/6小鼠为主。使用最多的造模方法为高脂饲料法,饲料喂养周期集中在8周。高频检测指标为成石率、总胆固醇、磷脂、总胆红素、总胆汁酸等。较多使用的干预方式为中药复方、西药和单味中药或提取物,西药干预以熊去氧胆酸(Ursodeoxycholic acid,UDCA)为主,中药干预以中药复方为主,还包括针灸、运动、饮食等其他干预方式。实验设立阳性对照药多为UDCA。结论随着胆石症动物模型的不断完善和发展,目前有较多种造模方法都较好地模拟了胆石症中西医临床表现特点,但也存在一定局限性。该文分析结果可为胆石症模型的选择、应用和完善提供参考。 展开更多
关键词 数据挖掘 胆石症 动物模型 中西医临床 病证结合
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