High Density Lipoprotein Phospholipids as a Marker of Coronary Heart Disease of Shen-Yang Deficiency Syndrome

Objective: To seek a new biochemical index for diagnosis of coronary heart disease (CHD)of shen-Yang deficiency syndrom (CHD-SYD). Methods: Sixty-one patients with CHD were divided into 3 groups according to their TCM Syndrome type, 10 patients in the group without Xin-Qi deficiency (Group A), 25 in the group with Xin-Qi deficiency but without Shen-Yang deficiency (Group B) and 26 in the group both with Xin-Qi deficiency and Shen-Yang deficiency (Group C). Levels of 17-hydroxy-corticosteroid in urine (urinary 17-OHCS) per 24 hrs, and serum level of high density lipoprotein cholesterol (HDL-C) and high density lipoprotein phospholipid (HDL-PL) in them were determined in synchrostep and compared with those in the control group of 23 healthy aged persons. urinary 17-OHCS per 24 hrs was taken as the diagnostic standard to screen a new index for diagnosis of Shen-Yang deficiency Syndrome, and preliminary appraisal to the index was made. Results: Serum HDL-PL in the CHD-SYD patients( Group C) was 616±157 mg/L, which was obviously lower than that in the patients of Group A and B. With low HDL-PL (<650 mg/L) used as the index to diagnose CHD-SYD, the sensitivity was 73%, the specificity 86% and the accuracy 80%. Conclusion: HDL-PL <650 mg/L could be adopted as an index for CHD-SYD diagnosis, which is simple and practical.

Treatment of insomnia by differentiation of yang deficiency syndrome

Insomnia has become one of the common clinical diseases.In recent years,it has been found that patients with insomnia of Yang deficiency type are more and more common,and the trend of rejuvenation gradually appears,which seriously affects the normal progress of people's life,work and study.Clinical treatment through syndrome differentiation,mainly from the heart,spleen,kidney three viscera yang deficiency,on the basis of the warm yang method to add Qianzhen tranquilizing products,and pay attention to multiple organs as diseases,add moisture,blood The qi thing,while not forgetting the psychological counseling,adjusting the body and mind,and achieving a certain clinical effect,can provide ideas for the treatment of this disease.

Preventive and therapeutic effect of long snake moxibustion on psoriasis with yang deficiency and external cold syndrome based on the theory of "treatment of winter disease in summer"

Psoriasis is a chronic inflammatory skin disease with multiple layers of silvery white scales on the surface of erythema papule as the main clinical characteristics,of which yang-deficiency external cold psoriasis is refractory,recurrent and severe in winter and mild in summer,which has a great impact on patients'physical and mental health and quality of life.Traditional Chinese medicine has unique insights in the treatment of psoriasis,both curative effect and safety,have obvious advantages.Based on the concept of"winter disease and summer treatment",long-snake moxibustion gives full play to its functions of warming the kidney,invigorating the marrow,warming the meridians,activating blood circulation and removing blood stasis,so as to restore the deficiency of Yang in patients with psoriasis with external cold syndrome,enhance disease resistance,and prevent psoriasis recurrence or aggravation in winter.Therefore,based on the theory of"winter disease and summer treatment",this paper preliminarily discusses the mechanism of long-snake moxibustion in the prevention and treatment of psoriasis with external cold syndrome of Yang deficiency,and provides new ideas and directions for the prevention and treatment of psoriasis with traditional Chinese medicine.

Clinical observation on efficacy of compound of warming yang, descending turbidity and dredging collaterals in the treatment of diabetic kidney disease with Yin-Yang deficiency and blood stasis syndrome

Objective:To observe the clinical efficacy of compound of owarming yang,descending turbidity and dredging collaterals in the treatment of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome.Methods:Seventy-six patients of diabetic kidney disease with yin-yang deficiency and blood stasis syndrome were randomly divided into observation group and control group,thirty-eight cases in each group.The control group was given conventional western medicine treatment,while the observation group took compound of owarming yang,descending turbidity and dredging collaterals orally on the basis of conventional western medicine treatment.The course of treatment covered for one month.Before and after treatment,we observed the scores of traditional Chinese medicine symptoms,indicators of renal function[serum creatinine(Scr),blood urea nitrogen(BUN),microalbuminuria(MALB)],indicators of glucose metabolism[fasting plasma glucose(FPG),2-hour postprandial blood glucose(2hPG),glycosylated hemoglobin(HbAlc)],indicators of hemorheology[plasma viscosity(PV),platelet aggregation rate(PAR),fibrinogen(FIB)],Cystatin-C(Cys-C),C-reactive protein(CRP)in the two groups.Results:After treatment,the clinical effect of the observation group was significantly better than the control group(P<0.05).The scores of traditional Chinese medicine symptoms,indicators of renal function(Scr、BUN、UAER),indicators of glucose metabolism(FPG、2hPG、HbAlc),indicators of hemorheology(PV、PAR、FIB),Cys-C and CRP in the two groups were decreased significantly compared with those before treatment(P<0.05),and the decrease in the observation group was superior to that in the control group(P<0.05).Conclusion:Compound of warming yang,descending turbidity and dredging collaterals has remarkable efficacy in treating of diabetic kidney disease patients with yin-yang deficiency and blood stasis syndrome by alleviating clinical symptoms,glucose metabolism,renal function and microcirculatory disturbance,and the mechanism related to alleviation of microinflammation.

Clinical Research of Zhenwu Decoction Combined with Tingli Dazao Xiefei Decoction in the Treatment of Chronic Heart Failure with Edema Syndrome due to Yang Deficiency

[Objectives]The paper was to investigate the clinical effects of Zhenwu Decoction combined with Tingli Dazao Xiefei Decoction in the treatment of chronic heart failure with edema syndrome due to yang deficiency.[Methods]Eighty patients with chronic heart failure were randomly divided into 2 groups(control group and treatment group),with 40 cases in each group.The patients in the control group were treated with conventional western medicine for 14 d,and the patients in the treatment group were treated with Zhenwu Decoction and Tingli Dazhao Xiefeng Decoction on the basis of the control group for 14 d.The curative effect of traditional Chinese medicine(TCM)syndrome score,left ventricular ejection fraction(LVEF),plasma N-terminal brain natruretic peptide precursor(NT-proBNP)and New York Heart Association(NYHA)functional class were compared between the two groups before and after treatment.Minnesota living with heart failure questionnaire in the principle of Chinese civilization and traditional medicine characteristics(C-MLHF)at admission and 1 month after discharge were compared between the two groups.[Results]After treatment,the total effective rate of TCM syndrome score in the treatment group was 82.50%,and that in the control group was 67.50%.The curative effect of TCM syndrome score in the treatment group was better than that in the control group(P<0.05).After treatment the LVEF in both groups was increased compared with that before treatment,and the NT-proBNP level was decreased compared with that before treatment(P<0.05),and those in the treatment group were better than those in the control group.The total effective rate of cardiac function in the treatment group was 87.50%,and that in the control group was 65.00%.The improvement of cardiac function in the treatment group was better than that in the control group(P<0.05).One month after discharge,C-MLHF scores in both groups were decreased compared with those before treatment,and that in the treatment group was lower than in the control group(P<0.05).[Conclusions]Zhenwu Decoction combined with Tingli Dazao Xiefei Decoction based on traditional western medicine treatment could improve the clinical efficacy,symptoms and quality of life of patients in the treatment of chronic heart failure with edema syndrome due to yang deficiency.

Moxibustion plus acupuncture improves the efficacy and quality of life of patients with polycystic ovary syndrome: A randomized controlled trial

Objective:To observe the effect of moxibustion combined with acupuncture on the efficacy and quality of life of spleen-kidney-yang-deficiency patients with polycystic ovary syndrome(PCOS).Materials and Methods:A total of 90 patients with PCOS of spleen-kidney yang deficiency type from January 2020 to March 2021 were selected and randomly divided into three groups,30 patients each in the moxibustion group,acupuncture group,and moxibustion combined with acupuncture group(combined group).The changes of body mass index(BMI),waist-to-hip ratio(WHR),fasting insulin(FINS),fasting plasma glucose(FPG),homeostasis model assessment-insulin resistance index(HOMA-IR),follicle-stimulating hormone(FSH),luteinizing hormone(LH),testosterone(T),triglycerides(TG),total cholesterol(TC),traditional Chinese medicine(TCM)clinical symptom score,efficacy,and quality of life score in the three groups were observed before and 3 months after treatment.Results:After treatment,(1)compared with the moxibustion and acupuncture groups,the combined group was more effective in reducing BMI(F=5.274,P<0.05)and WHR(F=8.246,P<0.05)in PCOS patients;(2)FINS,FPG,and HOMA-IR were reduced in all three groups,and the reduction in these three indicators was more pronounced in combined group(FINS:F=5.637,P<0.05,FPG:F=4.915,P<0.05,HOMA-IR:F=3.817,P<0.05);(3)The FSH,LH,and T levels of patients in the combined group were better than those in the remaining two groups(FSH:F=4,163,P<0.05,LH:F=5.098,P<0.05,T:F=7.038,P<0.05);(4)The TG and TC of patients in the combined group were lower than those in the remaining two groups(TG:F=4.806,P<0.05,TC:F=3.828,P<0.05);(5)The TCM clinical symptom score of the combined group was significantly lower than those of the moxibustion and acupuncture groups(F=4.547,P<0.05);(6)The quality of life of patients in the combined group improved more significantly than the moxibustion and acupuncture groups(F=6.239,P<0.05);(7)The total effective rate of the combined group was higher than that of the moxibustion and acupuncture groups(χ2=6.947,P=0.031).Conclusion:The combination of moxibustion and acupuncture can effectively reduce the BMI and WHR of PCOS patients,improve the endocrine function,sex hormone level,TCM symptoms and quality of life of patients,and has significant efficacy and high safety,which is worthy of wide clinical application.

300 CASES OF MENOPAUSAL SYNDROME TREATED BY ACUPUNCTURE

Caused by hypo-ovarianism, menopausal syndrome usually occurs in women aged from 45-55 years. With high incidence and various symptoms, the disease often severely jeopardize the health of the women. The authors had treated 300 cases of menopausal syndrome by acupuncture and obtained a good result.

浅谈颜红教授温阳法治疗抑郁症低动力症状

“低动力”为抑郁症的常见特征,表现为精力减退、疲劳感、反应迟缓、性欲减退等,严重影响患者的生活、工作、社交能力。作者随第七批全国老中医药专家学术经验继承老师、天津市名中医颜红教授学习,发现临床上此类症状可归为阳虚证,由于患者长期七情内伤、思虑过度,使情志失遂,进而导致阳气不振、心神失养。治以温阳之法,振奋阳气,可有效改善抑郁症患者低动力症状,值得临床推广使用。

复心合剂治疗阳虚水泛型心肌梗死后心力衰竭的前瞻性临床研究

目的探讨复心合剂治疗阳虚水泛型心肌梗死后心衰患者临床疗效及对血清心肌损伤、心室重构相关指标的影响。方法将92例阳虚水泛型心肌梗死后心衰患者随机分为观察组与对照组各46例。对照组给予西医基础治疗,观察组在对照组治疗基础上加服复心合剂,治疗前后评估2组患者的中医证候积分,超声心动图指标[左心室射血分数(LVEF)、左心室Tei指数、每搏输出量(SV)],血清心肌损伤指标[血清N末端B型利钠肽原(NT-ProBNP)水平、血清高敏心肌肌钙蛋白I(hs-cTnI)水平、肌酸激酶同工酶(CK-MB)水平],血清心室重构指标[缺氧诱导因子1α(HIF-1α)、可溶性生长刺激表达基因2蛋白(sST2)、血管紧张素Ⅱ(AngⅡ)],明尼苏达州心功能不全生命质量量表(MLHFQ)变化情况,治疗后随访1年观察2组患者主要不良心血管事件发生情况。结果治疗后,2组中医证候积分均显著降低(P<0.01),观察组优于对照组(P<0.05,P<0.01)观察组中医临床总有效率优于对照组(P<0.05);2组患者血清超声心动图指标,心肌损伤、心室重构指标及MLHFQ评分均显著降低(P<0.01),观察组优于对照组(P<0.01)。随访期间,观察组治疗后全因死亡率、恶性心律失常率、急性心力衰竭率均显著低于对照组(P<0.05,P<0.01)。结论复心合剂治疗阳虚水泛型心肌梗死后心衰患者临床疗效显著,疗效机制可能与其减轻心肌损伤、抑制心室重构有关。

强心方治疗心肾阳虚型慢性心力衰竭回顾性队列研究

目的 回顾性分析强心方治疗心肾阳虚型慢性心力衰竭(chronic heart failure,CHF)的短期与长期临床疗效。方法 观察2015年1月—2020年12月上海中医药大学附属市中医医院收治的217例CHF患者,并根据是否服用强心方治疗分为治疗组(119例)与对照组(98例)两组队列。比较两组患者NYHA分级疗效、中医证候积分、心超、BNP、cTnl指标以及生存预后情况、不良反应发生率等指标。结果 治疗组患者治疗期间NYHA心功能评分、中医证候、心超、BNP指标等改善情况显著优于对照组(P<0.05)。截至2023年10月最后随访时间,治疗组患者生存率显著高于对照组(P<0.05),且在高钾血症、肾功能损害、乏力、咳嗽等不良反应发生率显著低于对照组(P<0.05)。结论 强心方联合西医治疗不仅能够改善CHF短期症状,同时有效增强了CHF患者长期生活质量及生存率,并在一定程度上缓解长期CHF治疗所导致的不良反应。

瑞格列奈片联合加味肾气丸治疗阴阳两虚型2型糖尿病临床观察

目的分析瑞格列奈片联合加味肾气丸对2型糖尿病阴阳两虚型患者的治疗效果。方法纳入2020年10月—2021年10月山东省枣庄市薛城区人民医院100例阴阳两虚型2型糖尿病患者进行探究,以单双号方式分两组,对照组使用常规治疗和瑞格列奈片治疗,观察组在此基础上联合加味肾气丸。通过症状积分观察两组疗效,并对比其血糖和临床指标。结果治疗后,观察组空腹血糖、餐后2 h血糖、糖化血红蛋白数据低于对照组(P<0.05);观察组血清视黄醇结合蛋白4、白细胞介素-6、尿N-乙酰-β-D-葡萄糖苷酶数据均低于对照组(P<0.05)。观察组的主要症状、次要症状积分低于对照组(P<0.05)。结论瑞格列奈片联合加味肾气丸治疗阴阳两虚型2型糖尿病患者,可以减轻炎性反应,提升抗氧化、抗纤维化能力,并能够减轻患者症状,对于控制并发症、延缓病情进展有着积极作用,值得推广。

消水圣愈汤治疗老年肺源性心脏病临床观察

目的探讨消水圣愈汤对老年慢性肺源性心脏病(CPHD)患者血栓前状态指标及血清白细胞介素-8(IL-8)和肽素(Copeptin)水平的影响。方法将117例老年CPHD患者随机分为对照组(58例)和试验组(59例)。对照组予常规对症治疗,试验组在对照组的基础上予消水圣愈汤治疗,两组均治疗4周。比较两组临床疗效、血栓前状态指标及血清IL-8、Copeptin水平。结果治疗后,试验组总有效率为94.92%(56/59),高于对照组的79.31%(46/58)(P<0.05)。与对照组比较,试验组治疗后血浆黏度、血浆纤维蛋白原(FIB)水平、血清D-二聚体(D-D)、血管性假血友病因子(vWF)、内皮素(ET-1)水平较低,血清IL-8、Copeptin水平较低(P<0.05)。结论消水圣愈汤能明显改善老年CPHD患者血栓前状态,减轻炎症反应,促进心功能恢复,临床疗效显著。

升阳泻湿法治疗非酒精性脂肪性肝病初探

非酒精性脂肪性肝病是目前的多发病,为多因素所致,严重影响公共健康,目前对于该病的证治报道较多。该病的临床表现多数不典型,病机证候复杂,笔者汲取李东垣理论思想中升发脾之清气,以及黄元御理论思想中泻湿疏木的治法,把二者进行优化组合,拟定了升阳化湿,培土疏木为治疗大法运用于临床,立足于“湿”,分为“湿浊内蕴”和“脾虚湿困”2个证型,驭繁就简,取得了理想的临床疗效。

The Effect of Hormones of the Hypothalamic-pituitary-target Gland Axes in a Kidney-Yang Deficiency Syndrome Model

Kidney-yang deficiency syndrome(KYDS)is a diagnostic pattern in the traditional Chinese medicine.Studies have shown that KYDS is related to the functional disorder of hormones of the hypothalamic-pituitary-target gland axes.The standard procedure used to mimic KYDS is the injection of a high dose of exogenous glucocorticoid(hydrocortisone and corticosterone).Such a model showed symptoms such as exhaustion,body twists,cold limbs,lying crowded together,decreased rectal temperature,sexual dysfunction,decreased reaction speed,reduced spontaneous activity,hair loss,loss of appetite,and weight loss.Moreover,the model manifested an imbalance in mutual control among the hormones of the pituitary-target gland axes,including adrenocorticotrophic hormone,CORT,CRH,thyroid-stimulating hormone,triiodothyronine,thyroxine,T,E2,follicle-stimulating hormone,luteinizing hormone,and 17-OHCS.

The Change-Over of Yin-yang and Gene Regulation in Kidney Deficiency Syndromes

The present paper studies gene regulation in kidney deficiency syndromes from the simple Nephrotic Syndrome and with the principle of positive-negative regulation to control the change-over of yin-yang, the modern molecular biological techniques can be used, such as gene chip, representational difference analysis (RDA) and gene sequence analysis, so as to investigate the inner relationship between the genes and kidney deficiency syndromes and prove the effect given by these genes on the pathophysiological status of change-over of yin-yang in kidney deficiency syndromes. This philosophical approach and method can also be adopted for studies of the related genes in other TCM syndromes.

The Fourier Transform Infrared Spectra of the Key Organs Derived from Kidney(Shen)-Yang Deficiency Syndrome Mice

Objective:To explore an approach to rapidly and accurately identify the compounds as biomarkers of Chinese medicine(CM)syndromes.Method:The Fourier transform infrared(FT-IR)spectrometry was applied to investigate the characteristic components of a mice model of Kidney(Shen)-yang deficiency syndrome(KDS),and the remedial effect of a typical CM formula Shenqi Pill(肾气丸).Thirty-six females and 18 males of Balb/c mice were randomly divided into KDS,Shenqi or control group.The females and males of the same group freely were mated for 96 h,and the males were taken out and only the female mice were raised.Females of the KDS group were threatened by a ferocious cat every other day for 14 d.After delivery,the KDS,or gestational threatened,offspring were raised at standard condition for 11 weeks.Then 10 male offspring were randomly selected,anaesthetized and their representative organs,i.e.testes,kidneys,lungs and feet were collected,for the FT-IR scan.Mice of the Shenqi group were intragastric administered Shenqi Pill;while mice in the KDS and control groups were given the same volume of saline.Results:The attenuated birth outcomes of the KDS group were displayed.The remarkable FT-IR differences of all organs between KDS mice and healthy control were mainly at 1,735-1,745 cm^(-1)(indicating the increased levels of lipids)and at 1,640-1,647 cm^(-1)and 1,539-1,544 cm(-1)(displaying the decreased proteins).No statistic FT-IR difference between Shenqi and control mice was observed.Conclusion:In accordance with major traits of KDS,prenatal stress extensively impaired the building up of proteins and resulting in the excessive lipid storage,and FT-IR could effectively identify the biomarkers of KDS.

血清皮质醇与血管性轻度认知障碍肾阳虚证患者认知功能的相关性研究

目的探讨血清皮质醇与血管性轻度认知障碍肾阳虚证患者认知功能之间的关系。方法选取64例血管性轻度认知障碍肾阳虚证患者。根据血清皮质醇中位数分为高皮质醇组和低皮质醇组,各32例,收集患者一般临床资料、血清皮质醇指标,并进行神经心理学量表及肾阳虚量表测评。采用相关性分析及线性回归分析探讨血清皮质醇与血管性轻度认知障碍肾阳虚证患者认知功能之间的关系。结果与低皮质醇组相比,高皮质醇组的高血压病、脑血管病比例更高,MoCA、MMSE、AESC量表评分更低(P<0.05),ADL、HAMD、肾阳虚证辨识量表评分更高(P<0.05)。相关性分析结果显示高皮质醇与ADL、HAMD、肾阳虚辨识量表评分均呈正相关,与MoCA、MMSE、AESC量表评分均呈负相关(P<0.001)。线性回归分析结果显示高皮质醇为MoCA量表评分的独立危险因素,血管性轻度认知障碍肾阳虚证患者的血清皮质醇水平越高,MoCA量表评分越低(P<0.001),认知损害越严重。结论血清皮质醇的升高可能是血管性轻度认知障碍肾阳虚证患者认知功能损害的潜在因素。

温阳通络法联合小切口引流术治疗粉刺性乳痈患者的疗效观察

目的 观察温阳通络法联合小切口引流术治疗阳虚痰凝证型粉刺性乳痈患者的临床疗效。方法 选取2018年1月1日—2020年3月31日期间就诊于上海岳阳中西医结合医院乳腺病科的粉刺性乳痈患者114例作为研究对象,按随机数字表法分为对照组和治疗组,每组各57例。对照组予手术治疗,治疗组予温阳通络加减方联合小切口引流术。治疗4个月后观察比较两组患者临床疗效,治疗前后乳房外形、SF健康调查简表积分、血清炎症指标[白介素-6(Interleukin-6,IL-6)、白介素-8(Interleukin-8,IL-8)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)]及血清免疫指标[免疫球蛋白A(Immunoglobulin A,IgA)、免疫球蛋白G(Immunoglobulin G,IgG)、免疫球蛋白M(Immunoglobulin M,IgM)];治疗6个月后比较两组患者复发情况。结果 治疗后治疗组临床总有效率96.49%(55/57)明显高于对照组78.95%(45/57),差异有统计学意义(P<0.05)。治疗后两组患者乳房外形JCRT评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组乳房外形JCRT评分明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者SF-36健康简表评分均较治疗前升高,差异有统计学意义(P<0.05);且治疗组SF-36健康简表评分明显高于对照组,差异有统计学意义(P<0.05)。治疗后两组患者血清炎症IL-6、IL-8、TNF-α指标均较治疗前降低,差异有统计学意义(P<0.05);且治疗组血清炎症IL-6、IL-8、TNF-α指标明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者血清免疫IgA、IgG、IgM指标均较治疗前升高,差异有统计学意义(P<0.05);且治疗组血清免疫IgA、IgG、IgM指标明显高于对照组,差异有统计学意义(P<0.05)。6个月后,对两组治疗有效患者进行随访,其中对照组复发9例,复发率为20%(9/45),治疗组复发3例,复发率为5.45%(3/55),两组患者复发率比较,差异有统计学意义(P<0.05)。结论 温阳通络法加减联合小切口引流术治疗阳虚痰凝证粉刺性乳痈临床疗效显著,复发率低,能够顾护正气,减轻炎症反应,增强患者免疫力,同时对患者乳房外形保留程度更好,生活影响更少。

严氏苍山太阳炷燎穴位敷贴治疗阳虚血瘀型慢性心力衰竭的临床研究

目的观察严氏苍山太阳炷燎穴位敷贴治疗阳虚血瘀型慢性心力衰竭的临床疗效。方法将145例阳虚血瘀型慢性心力衰竭患者随机分为对照组73例、治疗组72例,两组均给予标准化西药治疗,对照组加用空白自发热贴膏,治疗组加用“严氏苍山太阳炷燎穴位敷贴”药物自发热贴膏,两组疗程均为90 d。观察临床疗效,比较中医证候积分、中医主次症与兼症分层、明尼苏达心力衰竭生活质量量表(MLHFQ)评分、纽约心脏病协会(NYHA)心功能分级、6 min步行试验(6MWT)距离以及B型钠尿肽(BNP)水平等指标的变化情况。结果①试验过程中,对照组脱落8例、治疗组脱落7例,最终完成试验者130例,其中治疗组65例、对照组65例。②治疗前后组内比较,两组中医证候积分均降低(P<0.05);组间治疗后比较,治疗组积分下降更为明显(P<0.05)。③治疗后,治疗组中医主次症与兼症分层得到改善(P<0.05),且治疗组的改善情况优于对照组(P<0.05)。④治疗前后组内比较,两组MLHFQ评分均降低(P<0.05);组间治疗后比较,治疗组MLHFQ评分较对照组显著降低(P<0.05)。⑤治疗后,两组NYHA心功能分级均得到改善(P<0.05),且治疗组的改善情况优于对照组(P<0.05)。⑥治疗前后组内比较,两组6MWT距离均较治疗前增加(P<0.05);组间治疗后比较,治疗组6MWT距离增加较对照组更明显(P<0.05)。⑦治疗前后组内比较,两组BNP水平均降低(P<0.05);组间治疗后比较,治疗组BNP水平显著低于对照组(P<0.05)。⑧两组各项安全性指标均未见明显异常。结论严氏苍山太阳炷燎穴位敷贴对阳虚血瘀型慢性心力衰竭患者临床症状与BNP的改善、运动耐量的提升及生活质量的提高都具有积极促进作用,且安全性好。