Initial Pre-stress Finding and Structural Behaviors Analysis of Cable Net Based on Linear Adjustment Theory

The tensile cable-strut structure is a self-equilibrate pre-stressed system.The initial pre-stress cal- culation is the fundamental structural analysis.A new numerical procedure was developed.The force density method is the cornerstone of analytical formula,and then introduced into linear adjustment theory;the least square least norm solution,the optimized initial pre-stress,is yielded.The initial pre-stress and structural performances of a particular single-layer saddle-shaped cable-net structure were analyzed with the developed method,which is proved to be efficient and correct.The modal analyses were performed with respect to various pre-stress levels.Finally,the structural performances were investigated comprehensively.

Dynamic analysis of double-layer and pre-stressed multi-limb six-axis force sensor

In order to adapt to the specific task, the six-axis dynamic contact force between end-effectors of intelligent robots and working condition needs to be perceived. Therefore, the dynamic property of six-axis force sensor which is installed on the end-effectors of intelligent robots will have influence on the veracity of detection and judgment to working environment contact force by intelligent robots directly. In this paper, dynamic analysis to double-layer and pre-stressed multi-limb six-axis force sensor is conducted. First, the structure of the sensor is introduced, and the limb number is confirmed by introducing the related definitions of convex analysis. Then, based on vibration of multiple-degree-of-freedom system, a mechanical vibration simplified model of double-layer and pre-stressed multiple limb six-axis force sensor is set up. After that, movement differential equations of sensor and the response of analytical expression are deduced, and the movement differential equations is solved. Finally, taking the double-layer and pre-stressed seven limb six-axis force sensor as an example, numerical calculation and simulation of deriving result is conducted, which verify the correctness and feasibility of the theoretical analysis.

Structure-based multi-ligand molecular modeling to predict the synergistic effects of limonin and obacunone from Simiao pill against nitric oxide synthase 3 associated with hyperuricemia

Hyperuricemia(HUA)mainly occurs because of purine metabolism disorders.We recently proposed that limonin from Simiao pill may have therapeutic effects on nitric oxide synthase 3(NOS3)that is related to HUA.Concurrently,our previous work employed a new method,structure-based multi-ligand molecular modeling,to identify potential agents from a herbal formula that may produce synergistic effects and may have the potential to develop combination drugs.Therefore,we employed multi-ligand modeling to seek compounds with potential synergistic effects with limonin against NOS3.We obtained 403 multi-ligand docking results between 403 compounds and the limonin-NOS3 complex(average affinity–8.297 kcal/mol).Then we selected the top 10 highest binding affinity compounds for virtual pharmacokinetic and toxicity screening and we found that only obacunone passed all filters.We further subjected obacunone,bound to limonin and NOS3,to molecular dynamics simulations.We found that the NOS3-limonin-obacunone complex was more stable than the NOS3-limonin complex,based on the root mean square deviation of backbone Cαatoms and root mean square fluctuation,which suggests that synergistic effects may exist between limonin and obacunone.Further cell and animal experimental research is required to verify our results.

Synergistic effects and kinetics analysis for co-pyrolysis of vacuum residue and plastics

This study utilizedathermogravimetric analyzer to assess the thermal decomposition behaviors and kinetics properties of vacuum residue(VR)and low-density polyethylene(LDPE)polymers.The kinetic parameters were calculated using the Friedman technique.To demonstrate the interactive effects between LDPE and VR during the co-pyrolysis process,the disparity in mass loss and mass loss rate between the experimental and calculated values was computed.The co-pyrolysis curves obtained through estimation and experimentation exhibited significantdeviations,whichwerei influencedby temperature and mixing ratio.A negative synergistic interaction was observed between LDPE and VR,although this inhibitory effect could be mitigated or eliminated by reducing the LDPE ratio in the mixture and increasing the co-pyrolysistemperature.Theco-pyrolysisprocess resulted in a reduction in carbon residue,which could be attributed to the interaction between LDPE and the heavy fractions,particularly resin and asphaltene,present in VR.These findings align with the pyrolysis behaviors exhibited by the four VR fractions.Furthermore,it was observed that the co-pyrolysis process exhibited lower activation energy as the VR ratio increased,indicating a continuous enhancement in the reactivity of the mixed samples during co-pyrolysis.

Stress Analysis of New Type Pre-Stressed Anchor Bearing Plate Combining Stamping with Welding Forming and Its Anchorage Zone

An anchor bearing plate transfers the anchoring force from anchor plate to the concrete and the pre-stress is formed in the concrete structure. Currently, the main type of anchor bearing plate is cast iron. It is brittle during transportation and tension process. This paper presents a new type of anchor bearing plate combined stamping with welding forming. The structure of the new type anchor bearing plate is introduced. The stress states of the anchor bearing plate and anchorage zone under work are studied. Various specifications of anchor bearing plate are studied by ANSYS finite element analysis software following the AASHTO specification. The analysis results are compared with the results of the same type of OVM round-shaped anchor plate. The study results show that the new pre-stressed anchor plates combined stamping with welding forming are feasible and more sturdy which can meet the engineering demand.

Synergistic effect of pinellia total alkaloids and uncaria total alkaloids on anticonvulsant action in mice and rats

Aim To investigate the synergistic effect of the combination of pinellia total alkaloid （PTA） and uncaria total alkaloid （UTA）, and explore the mechanism of anticonvulsant action. Methods Anticonvulsant and toxic effect profiles of combinations of PTA with UTA, alone and at three fixed ratios of 1：4, 1 ：1, 4：1, were evaluated in maximal electroshock （MES）-induced seizures and acute toxicity test in mice. Respective ED50 and LD50 were calculated with Bliss＇s method. Their synergistic effect were evaluated by isobolographic analysis and allowed the determination of benefit indices （BI） for respective combinations. The model of convulsive rats kindled by penicillin topically injected into cortex was used to investigated the content of Glu, Asp, Gly and GABA in hippocampus using high performance liquid chromatography （HPLC）. Results Combinations of PTA and UTA at the ratio of 4：1 were synergistic in MES test and antagonistic in acute toxicity test, showing the best profile for combinations of PTA with UTA. In contrast, the ratios of 1 ：4 and 1 ： 1, despite synergistic in MES test, were additive in acute toxicity test. The 4：1 combination and two drugs alone significantly decreased Glu level and increased GABA level in the hippocampus, but the GABA level in the 4：1 combination group was higher than that in the two drugs alone groups. They did not have significant influence on the levels of ASp and Gly. Conclusion Combinations of PTA and UTA at 4：1 ratio demonstrated synergistic effect in anticonvulsant action and antagonistic effect in toxicity. The anticonvulsant mechanism might be related to decreasing the excitability of Glutamatergic neurons and increasing the inhibition of GABAergic neurons.

Bimetallic synergistic Pd-Pt icosahedra as highly active peroxidase-like mimics for colorimetric analysis

Thanks to the synergistic effect,the bimetallic catalysts show better catalytic activity than the single metal cat-alysts and become a focus of research in heterogeneous catalysis.In this study,we successfully prepared Pd-Pt icosahedra which show high peroxidase-like activity under the synergistic effects of Pd and Pt.V max of the Pd-Pt icosahedra was significantly enhanced by 1.66 times for 3,3’,5,5’-tetramethylbenzidine(TMB)as the substrate and 1.23 times for H_(2)O_(2) as the substrate,compared to that of the Pd icosahedra alone.By harnessing the supe-rior peroxidase-like activity of Pd-Pt icosahedra,we successfully utilized Pd-Pt icosahedral nanozymes in various biological analyses based on colorimetry.In most cases,using a Pd-Pt icosahedra/H_(2)O_(2)/TMB system,glucose,glutathione(GSH),acid phosphatase(ACP),and alkaline phosphatase(ALP)were detected over a wide range of 0.05∼0.20 mM,0∼20 mM,0∼10 U/L and 0∼12 U/L.In this study,we prepared a novel bimetallic nanozyme that exhibited excellent peroxidase-like activity owing to the bimetallic synergistic effect,thus demonstrating the promising potential of Pd-Pt icosahedra in the field of bioanalysis.

家庭、学校、社会三方协同作用对青少年体质健康的影响

该文聚焦于家庭、学校、社会三方协同作用对青少年体质健康的影响,主要以济南市城区内青少年学生及其家长为研究对象,运用文献资料、问卷调查、数理统计等方法,探讨家庭、学校、社会协同作用对青少年体质健康的影响,得出结论:家庭的体育认知态度与青少年参与体育运动的频率呈正相关;家庭的体育认知态度与青少年的体育参与态度表现出较强的相关性。这也说明了家庭体育教育对青少年体质健康的重要作用。同样,社会与学校在青少年的体质健康培养中也表现出了一定的影响作用。目前,强调家庭、学校、社会三方协同作用的背景下,青少年体质健康的培养仍存在一些问题,比如三方并未建立明确的培养机制,责、权不明的情况频频出现;三方没有形成明确的培养目标,而是各自为营,不能很好地发挥出三方协同的优秀效果等。针对以上问题,文章提出了相应建议,以期在三方协同作用下进一步促进青少年体质健康发展。

多因素协同作用下的页岩气井下管道腐蚀分析

国内西南地区某页岩气井下管道出现了不同程度的腐蚀,存在较大的安全隐患。为明确腐蚀类型和机理,开展了井下管道腐蚀分析。研究方法主要包括宏观观察、微观观察和成分分析、流体力学仿真。结果表明:冲刷-CO_(2)-SRB(硫酸盐还原菌)多因素协同作用下的腐蚀是页岩气井下管道的主要腐蚀类型。运行初期SRB的生长与富集造成了局部腐蚀,加入杀菌剂后SRB腐蚀停止,CO_(2)腐蚀在已经形成的局部腐蚀位置继续发展,液带砂和气带砂等流体冲刷作用促进了相关腐蚀的发生、发展。

嗜酸乳杆菌与枯草芽孢杆菌协同发酵玉米淀粉糖渣

通过微生物发酵可以改善风味,并消除营养抑制因子,从而实现玉米淀粉糖渣的高价值利用。该文采用嗜酸乳杆菌单菌固态发酵糖渣,乳杆菌活菌数为5.24×10^(8)CFU/g,进一步利用枯草芽孢杆菌、嗜酸乳杆菌协同发酵,嗜酸乳杆菌活菌数提升到1.50×10^(9)CFU/g,是单菌发酵的2.86倍。对双菌固态发酵工艺进行优化,在种子液接种量为7.8%,含水量为72%,初始pH为7.26时嗜酸乳杆菌活菌数达到5.05×10^(9)CFU/g,是优化前的3.37倍,对双菌发酵和单菌发酵产物进行组分、风味、口味等指标进行分析检测,结果表明发酵可以提升营养价值,同时还可以降低植酸含量并提高抗氧化能力。双菌发酵可获得更高的益生菌活菌数,并减少异味,增加类似坚果和脂肪的香气,改善口感。

基于灰色关联协同效应权重配置的费用预测模型

费用预测是复杂装备成本管理的核心内容。在同类型复杂装备仅有少量样本信息的情况下,为提高估算预测精度,解决贫信息下费用影响要素筛选困难、要素间由于协同效应导致的权重分配不合理、费用预测误差较大等问题,提出了一种基于灰色关联协同效应贡献度分配的要素权重配置方法。首先通过灰色关联度分析筛选相似样本及费用关键影响要素;然后,依据各要素在协同效应下对灰色关联度提高的贡献程度大小,参考Shapley值思想计算各要素的灰色比较关联重要性,以此确定权重;最后,构建相应的异阶参数灰色分数阶预测模型,对目标装备进行费用预测。通过与已有文献中的方法进行对比,结果表明所提方法有较高的预测精度且具有一定的适用性,能够挖掘小样本下费用影响要素间的潜在信息,更可以合理地分配要素权重,提高费用预测精度。

空间混合辐射环境器件单粒子在轨错误率预估及不确定度分析方法

针对空间混合辐射对器件单粒子在轨错误率的影响,基于典型静态随机存储器利用中国原子能科学研究院HI-13串列加速器以及钴源总剂量模拟辐照试验装置开展协合效应研究,发展了一种器件在混合辐射环境下的单粒子在轨错误率计算方法。并利用该方法计算了协合效应影响下的航天器典型任务周期器件的在轨错误率,同时分析了器件在轨错误率计算中的不确定度来源并计算了在轨错误率不确定度。结果表明,对于该类型器件,空间混合辐射场导致的协合效应将降低器件单粒子在轨错误率。

榆林市工业二氧化碳与大气污染物排放控制协同效应研究

在“双碳”背景下,了解工业二氧化碳与大气污染物排放之间的协同效应对于实现减污降碳具有重要意义。该研究以榆林市2015—2021年二氧化碳与大气污染物排放量为例。首先,利用灰色相关分析对榆林市工业碳排放影响因素的相关度进行计算。其次,对Kaya恒等式和LMDI模型进行拓展,分析影响二氧化碳及主要大气污染物排放的驱动效应。最后,对榆林市重点行业火力发电行业和镁冶炼行业进行协同性分析并对榆林市减污降碳提出建议。结果表明,协同减排效应是驱动大气污染物排放减少的第一大驱动效应。二氧化碳的排放与氮氧化物的排放相关性最强,且LMDI模型分析表明氮氧化物与二氧化碳协同减排具有显著的协同效应。研究结果可为榆林市减污降碳协同增效以及高质量发展提供科学依据,为政府在制定一系列更为有效且切实可行的环境保护政策提供理论基础。

SF_(6)放电分解产物荧光抑制光纤增强拉曼光谱动态高灵敏检测研究

分析SF_(6)放电分解产物组分和含量的动态变化是SF_(6)封闭式组合电器(Gas-Insulated Switchgear,GIS)状态诊断的关键。本文提出荧光抑制光纤增强拉曼光谱(Fiber-Enhanced Raman Spectroscopy,FERS)动态高灵敏检测方法。首先搭建了SF_(6)放电分解产物荧光抑制FERS检测系统,通过结合CCD数字滤波和小孔空间滤波的协同荧光滤波方法,系统信噪比提升228.4%;基于Allan方差分析确定了系统最佳积分时间为220 s。然后在2 bar压强、220 s积分时间下,基于标准混合气体样品分析确定了用于同时定性与定量分析SF_(6)放电分解产物SOF_(2),SO_(2)F_(2),COS,CF_(4),SO_(2),CO_(2),CO的特征拉曼谱峰,并计算得检测下限分别为1.95 ppm,1.78 ppm,0.83 ppm,2.41 ppm,0.93 ppm,2.51 ppm,6.69 ppm。最后通过连续168 h的GIS等比缩小模型局部放电实验证明了上述系统可实现SF_(6)放电分解产物的动态高灵敏检测,且与气相色谱法结果偏差小于±5%。实验结果表明,本文提出的检测方法可为GIS的安全运行提供技术支撑。

肥料增效剂的种类及作用原理

通过中国知网(CNKI)数据库,以“肥料增效剂”“硝化抑制剂”“脲酶抑制剂”“腐殖质”“腐殖酸”“微生物肥料”“氨基酸肥料”等为关键词搜索发表于2000—2023年的文献,并将获得的8805篇文献记录导入VOSviewer软件中进行关键词聚类分析。结果表明:肥料增效剂主要分为生物类和化学类两大类,其中化学类肥料增效剂主要为脲酶抑制剂类和硝化抑制剂类,生物类肥料增效剂主要为腐殖质类、氨基酸类、微生物类等。概述了生物类和化学类肥料增效剂的作用原理,提出了肥料增效剂在实际应用中存在的问题,并对今后肥料增效剂的创新方向提出了展望。

芦荟大黄素对α-葡萄糖苷酶的抑制机理及其与阿卡波糖的协同作用

为探讨芦荟大黄素与α-葡萄糖苷酶的相互作用,本实验采用酶抑制动力学、紫外光谱、红外光谱、荧光光谱等多种光谱分析法研究芦荟大黄素对α-葡萄糖苷酶的抑制机理,并研究芦荟大黄素与阿卡波糖联用的协同效应。结果显示,相较于阿卡波糖,芦荟大黄素具有更好的α-葡萄糖苷酶抑制效果,属于非竞争性和反竞争性的混合型抑制剂。紫外光谱结果表明芦荟大黄素与α-葡萄糖苷酶之间通过相互作用形成了新的复合物。红外光谱中酰胺基团的特征振动结果表明随着芦荟大黄素加入,α-葡萄糖苷酶结构构象发生变化。荧光猝灭实验结果说明,芦荟大黄素是以静态猝灭的方式猝灭α-葡萄糖苷酶的内源性荧光。此外,芦荟大黄素和阿卡波糖联用对α-葡萄糖苷酶活性有一定的协同抑制效果。本研究揭示了芦荟大黄素对α-葡萄糖苷酶的抑制作用机制,为未来将芦荟大黄素作为调节人体血糖的保健食品配方提供了实验依据。

长三角碳排放空间网络结构及协同减排效应

该研究基于修正的引力模型构建长三角地区碳排放空间关联网络矩阵,运用社会网络分析方法考察碳排放空间网络结构形态,并从整体、个体和空间聚类3个维度深入探究碳排放空间关联网络特征,同时对长三角地区的协同减排效应进行测算和分析。研究结果表明:(1)长三角地区的碳排放空间关联网络结构趋于复杂和稳定;(2)各节点城市在长三角地区碳排放空间关联网络中所处的地位和角色具有明显的非均衡性,苏州、无锡、常州和上海是碳排放空间关联网络中的核心节点;(3)碳排放空间关联网络划分为4个板块且板块间存在显著的溢出效应;(4)长三角地区的整体碳减排协同水平有很大提升空间,各个城市与上海的碳减排协同度差异较为显著。

中国省际能源高质量协同发展测度

新形势下中国能源发展面临来自国内外的多重挑战,亟须提高发展的质量和效益,以满足人民在经济、社会、生态等方面日益增长的需要。围绕安全可靠、绿色清洁、高效节能、能源共享、减污降碳、技术创新六个维度构建中国省际能源高质量发展指标体系,测度分析了中国30个省份2012—2022年的能源高质量发展水平和特征变化,并利用基于产品空间的复杂网络量化了不同能源高质量发展指标之间的协同关系,为推动省级能源高质量发展和确定能源高质量发展进程中的优先事项和政策一致性提供了科学支撑。结果表明,(1)2012—2022年全国整体及各区域能源高质量发展水平呈现稳步上升趋势,中南、西南地区各省份能源发展较为迅速,华东、中南地区整体能源发展水平较高,东北地区整体能源发展水平较低。(2)相比2012年,全国整体能源安全稳定性有所下降,技术创新性提升明显,省间能源共享水平差异大幅度缩小,广东、湖北、安徽等东中部省份技术创新水平明显增强,山东、四川等东部沿海及西南省份的能源结构“清洁化”程度不断提高,贵州、青海、河南、湖北减污降碳成效显著,但区域能源供需不平衡,宁夏与山西等煤炭大省“高投入、高能耗、低效益”的问题依然凸显。(3)终端电气化水平、绿色能源投资和能源基础设施建设投资三项指标与大量能源指标存在紧密的协同关系,将在未来实现能源高质量发展的过程中发挥关键作用。

多元主体环境规制组合如何实现降碳减污扩绿增长协同推进?

降碳减污扩绿增长协同推进是助力于经济高质量发展的重要抓手。如何实现降碳减污扩绿增长协同推进是当前政府、公众乃至学术界比较关注的焦点话题。基于“政府-市场-公众”框架以中国30个省份为案例,运用模糊集定性比较分析(fsQCA)方法、必要条件分析(NCA)和倾向得分匹配(PSM)方法,探讨政府环境规制、市场环境规制和公众环境规制多元主体环境规制组合对降碳减污扩绿增长协同推进的联动效应及其路径选择,探索性地识别出3类降碳减污协同推进的配适性选择方案,即由政府环境规制和公众环境规制多元组合共同解释的配饰模式,由政府环境规制、市场环境规制和公众环境规制多元组合共同解释的配饰模式以及由政府环境规制和市场环境规制多元组合共同解释的配饰模式。研究发现:①单一主体环境规制并不能构成降碳减污协同推进的必要条件,但是完善的环保制度发挥着普适性作用。瓶颈分析说明实现100%的降碳减污协同推进需要各种主体环境规制共同参与发挥效力。②政府、市场和公众多元环境规制“多重并发”,共4类环境规制组合能够实现降碳减污协同推进的效果,呈现出中国降碳减污协同推进的多元化实现路径和复杂机制。③进一步研究发现,政府环境规制-市场环境规制-公众环境规制多元联合型环境规制能够实现降碳减污扩绿增长协同推进的效果。这些发现对于中国各地区实施何种环境规制组合以实现降碳减污扩绿增长协同推进具有重要的理论意义与政策启示。

超声微波协同提取药桑叶生物碱及其保肝活性研究

本研究以药桑叶为原料,采用单因素结合响应面法优化了药桑叶生物碱的超声微波协同提取工艺,并采用四氯化碳致小鼠急性肝损伤模型评价了药桑叶提取物(MNLE)的保肝活性。结果表明药桑叶生物碱的最佳提取工艺为:料液比1∶54 g/mL,乙醇浓度79%,微波功率300~0 W(0~7 min),超声功率493 W,提取时间29 min,提取温度70℃,在此条件下生物碱提取率可达11.325 mg/g。药效学试验结果显示,与模型组相比,MNLE能明显降低血清谷丙转氨酶(ALT)、谷草转氨酶(AST)水平以及肝组织丙二醛(MDA)和一氧化氮(NO)水平(P<0.05或P<0.01),升高肝组织超氧化物歧化酶(SOD)和谷胱甘肽(GSH)水平(P<0.05或P<0.01),肝组织病理学变化也得到了明显改善。结果表明MNLE具有较好的保肝作用,其作用机制与其抗氧化活性相关。