A sample of 76 older adults (27 with diabetes and 49 without diabetes) were selected to judge three information factors, metamemory related to—drug organization—stress and physical activity in relation to their perc...A sample of 76 older adults (27 with diabetes and 49 without diabetes) were selected to judge three information factors, metamemory related to—drug organization—stress and physical activity in relation to their perception of self-care. In order to do so, an Integration Information Theory was considered to determine systematic cognitive algebra rules underlying judgment about 24 different health self-care scenarios. Results indicate that older adults without diabetes use a summative cognitive rule to integrate relevant health information but older adults with diabetes do not. Both groups agreed that metamemory was the most relevant factor to their self-care followed by stress and physical activity. However, valuation of these factors does depend on the type of group. Implications of these results to healthcare a behavioral nursing intervention are discussed in this paper.展开更多
In the process industry, automation and process control systems are widely implemented, information integration is however far away from satisfactory. It remains a hard job for senior managers to make decisions based ...In the process industry, automation and process control systems are widely implemented, information integration is however far away from satisfactory. It remains a hard job for senior managers to make decisions based on the plant-wide real-time integrated information. This paper proposes a multi-layer information integration platform. In the data integration level, the standard for the exchange of product (STEP) and the extensible markup language (XML) are used to unify these data of the chemical process. In the model integration level, the models are integrated by using the neutral model repository and CAPE-OPEN. In the integration of process task, the common object request broker architecture (CORBA) is used as the communication mediator. The XML is taken as the data standard. A uniform information platform is thus constructed and realized. The proposed information integration platform is satisfactorily implemented to solve the Tennessee Eastman (TE) problem.展开更多
Mobile communication standards have been developed into a new era of B5G and 6G.In recent years,low earth orbit(LEO)satellites and space Internet have become hot topics.The integrated satellite and terrestrial systems...Mobile communication standards have been developed into a new era of B5G and 6G.In recent years,low earth orbit(LEO)satellites and space Internet have become hot topics.The integrated satellite and terrestrial systems have been widely discussed by industries and academics,and even are expected to be applied in those huge constellations in construction.This paper points out the trends of two stages towards system integration of the terrestrial mobile communication and the satellite communications:to be compatible with 5G,and to be integrated within 6G.Based on analysis of the challenges of both stages,key technologies are thereafter analyzed in detail,covering both air interface currently discussed in 3GPP for B5G and also novel network architecture and related transmission technologies toward future 6G.展开更多
Ontology-based semantic information integration resolve the schema-level heterogeneity and part of data level heterogeneity between distributed data sources. But it is ubiquitous that schema semantics of information i...Ontology-based semantic information integration resolve the schema-level heterogeneity and part of data level heterogeneity between distributed data sources. But it is ubiquitous that schema semantics of information is identical while the interpretation of it varies with different context, and ontology-based semantic information integration can not resolve this context heterogeneity. By introducing context representation and context mediation to ontology based information integration, the attribute-level context heterogeneity can be detected and reconciled automatically, and hence a complete solution for semantic heterogeneity is formed. Through a concrete example, the context representation and the process in which the attribute-level context heterogeneity is reconciled during query processing are presented. This resolution can make up the deficiency of schema mapping based semantic information integration. With the architecture proposed in this paper the semantic heterogeneity solution is adaptive and extensive.展开更多
Prediction has become more and more difficult in mineral exploration, especially in the mature exploration environment such as Tongling copper district. For enhancing predictive discovery of hidden ore deposits in suc...Prediction has become more and more difficult in mineral exploration, especially in the mature exploration environment such as Tongling copper district. For enhancing predictive discovery of hidden ore deposits in such mature environment, the key strategies which should be adopted include the innovation of the exploration models, application of the advanced exploration techniques and integration of multiple sets of information. The innovation of the exploration models should incorporate the new metallogenic concepts that are based on the geodynamic anatomization. The advanced techniques applied in the mature exploration environment should aim at the speciality and complexity of the geological setting and working environments. The information synthesis is to integrate multiple sets of data for giving a more credible and visual prospectivity map by using the geographic imformation system(GIS) and several mathematical methods, such as weight of evidence and fuzzy logic, which can extract useful information from every set of data as much as possible. Guided by these strategies, a predictive exploration in Fenghuangshan ore field of Tongling copper district was implemented, and a hidden ore deposit was discovered.展开更多
This paper analyzes the flow of the process design an d the fountain of the technique data in a manufacturing enterprise, and discusse s the information flows between CAPP and other systems in CIMS, such as CAD syst e...This paper analyzes the flow of the process design an d the fountain of the technique data in a manufacturing enterprise, and discusse s the information flows between CAPP and other systems in CIMS, such as CAD syst em and Enterprise Resource Planning (ERP) system. And then, it discusses the pla ns of information integration between CAPP and CAD, as well as between CAPP and ERP. To design the processes of a product requires the manufacture information, such as blank material and machine tool, which is saved in a database in ERP. General ly, a traditional CAPP system considers the information of the manufacturing res ources, such as machine tool, as changeless. However, it is real changing, becau se the resources may be occupied or the machine tool may be under repair. Theref ore, in order to design the processes more reasonably, we must consider the real change of resources in a workshop. Creating a public resource database to suppo rt the real change of resources is put forward in this paper. With the public re source database, the resource integration between CAPP system and ERP is realize d; and by information collections in CAPP system, such as BOM, the material cons umption and man-hour consumption and their output to ERP, the information integ ration between CAPP system and ERP is realized.展开更多
A new information integration platform for computer integrated manufacturing system (CIMS) is presented, which is based on agent and CORBA. CORBA enhances the system integration because it is an industry-standard for ...A new information integration platform for computer integrated manufacturing system (CIMS) is presented, which is based on agent and CORBA. CORBA enhances the system integration because it is an industry-standard for interoperable, distributed objects across heterogeneous hardware and software platform. Agent technology is used to improve intelligence of integration system. In order to implement the information integration platform, we use network integration server to integrate network, design a generic database agent to integrate database, adopt multi-agent based architecture to integrate application, and utilize wrapper as CORBA object to integrate legacy code.展开更多
A combined approach of thermodynamic analysis and mixed-integer linear programming is presented for performing structural and parameter optimization in the integration of energy system of chemical processes. Tnermodyn...A combined approach of thermodynamic analysis and mixed-integer linear programming is presented for performing structural and parameter optimization in the integration of energy system of chemical processes. Tnermodynamic analysis is used to set up a superstructure configuration of energy system in order to reduce the space of search. The application of the combined approach is illustrated by a revamping integration of a large existing energy system in a refinery complex.展开更多
The theory and method of system integration for the real-time monitoring of core rock-fill dam filling con- struction quality are studied in this paper. First, the importance analysis of system integration factors is ...The theory and method of system integration for the real-time monitoring of core rock-fill dam filling con- struction quality are studied in this paper. First, the importance analysis of system integration factors is carried out with the analytic hierarchy process. Then, according to the analysis result of integration factors, the conceptual model of system integration is built based on function integration, index integration, technology integration and information integration, the index structure of core rock-fill dam filling construction quality control is constructed and the method of function integration and technology integration is studied. The mathematical model of process monitoring is built according to monitoring objective, process and indexes. Research results have been applied in Nuozhadu core rock-fill dam construction management, realizing system integration through building appropriate monitoring work flow and comprehensive information platform of digital dam.展开更多
Datong-Qinhuangdao line, as the first electrified double-track heavy-haul line dedicated to coal transport in China, extends from Datong in the west, and reaches Qinhuangdao in the east, opened to traffic in December,...Datong-Qinhuangdao line, as the first electrified double-track heavy-haul line dedicated to coal transport in China, extends from Datong in the west, and reaches Qinhuangdao in the east, opened to traffic in December, 1992, totaling 653 km with the designed annual traffic volume of 1×108 t. In order to meet the demands of national economic development, the transport capacity of the line must be enhanced greatly. Depending on independent innovation, MOR, for the first time in the world,realizes the integration between GSM-R and Locotrol, the integration between 800 MHz digital radio and Locotrol, and the integration between a single set of Locotrol and SS4 locomotive. Meanwhile, CR develops equipment portfolio for heavy-haul through combining 2 high power locomotives of HXD series (means harmony) with controllable EOT. Relying on integration and innovation, it succeeds in operating 20 kt-level combined heavy-haul train on Datong-Qinhuangdao line, which tripled the annual traffic volume of the line from 1×108 t in 2002 to 3×108 t in 2007.展开更多
BACKGROUND Sensory integration intervention is highly related to the child's effective interaction with the environment and the child's development.Currently,various sensory integration interventions are being...BACKGROUND Sensory integration intervention is highly related to the child's effective interaction with the environment and the child's development.Currently,various sensory integration interventions are being applied,but research methodological problems are arising due to unsystematic protocols.This study aims to present the optimal intervention protocol by presenting scientific standards for sensory integration intervention through meta-analysis.AIM To prove the effectiveness of sensory integration therapy,examine the latest trend of sensory integration studies in Korea,and provide clinical evidence for sensory integration therapies.METHODS The database of Korean search engines,including RISS,KISS,and DBpia,was used to search for related literature published from 2001 to October 2020.The keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this search.Then,a meta-analysis was conducted on 24 selected studiesRISS,KISS,and DBpia,was used to search for related literature published from 2001 to October 2020.The keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this search.Then,a meta-analysis was conducted on 24 selected studies.RESULTS Sensory integration intervention has been proven effective in children with cerebral palsy,autism spectrum disorder,attention deficit/hyperactivity disorder,developmental disorder,and intellectual disability in relation to the diagnosis of children.Regarding sensory integration therapies,1:1 individual treatment with a therapist or a therapy session lasting for 40 min was most effective.In terms of dependent variables,sensory integration therapy effectively promoted social skills,adaptive behavior,sensory processing,and gross motor and fine motor skills.CONCLUSION The results of this study may be used as therapeutic evidence for sensory integration intervention in the clinical field of occupational therapy for children,and can help to present standards for sensory integration intervention protocols.展开更多
The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to ...The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to promote the modernization of education.Starting from the connotation of the deep integration of information technology and education and teaching,this paper analyzes the existing problems in the current integration process,and puts forward innovative strategies from the aspects of concept,resources,model,and evaluation.Through measures such as building a smart teaching environment,enriching high-quality teaching resources,innovating teaching organization models,and establishing multiple evaluation systems,we will realize the deep integration of information technology and teaching,promote the reform of teaching and learning methods,improve the quality of personnel training,and provide strong support for the modernization of education.展开更多
With the development of the integration of production and education,chemical engineering and technology education is facing many new challenges and opportunities.The construction of a chemical virtual simulation pract...With the development of the integration of production and education,chemical engineering and technology education is facing many new challenges and opportunities.The construction of a chemical virtual simulation practice teaching system under the background of integration of production and education aims to improve students’learning efficiency and innovation ability with the help of virtual simulation technology,so as to meet the needs of future industrial development.This paper discusses the significance of the construction of the system,analyzes the difficulties and challenges that may be encountered in the construction process,and evaluates the effective strategies to strengthen the construction of the system.Through the introduction of virtual simulation technology,students can improve their practical skills and innovation ability,and better adapt to the development needs of industrialization and informatization.展开更多
In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a gene...In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM formulation.To mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing technique.By discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the PFEM.We express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)problem.Stresses,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point method.Consequently,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM formulation.Numerical experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM approaches.This work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.展开更多
The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which ...The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which not only provides the optical gain which is absent from native Si substrates and enables complete photonic functionalities on chip,but also improves the system performance through advanced heterogeneous integrated packaging.This paper reviews recent progress of silicon-based optoelectronic heterogeneous integration in high performance optical interconnection.The research status,development trend and application of ultra-low loss optical waveguides,high-speed detectors,high-speed modulators,lasers and 2D,2.5D,3D and monolithic integration are focused on.展开更多
As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning ...As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning carbon-based semiconductor technology has become one of the most disruptive technologies in the post-Moore era.As one-dimensional nanomaterials,carbon nanotubes(CNTs)are far superior to silicon at the same technology nodes of FETs because of their excellent electrical transport and scaling properties,rendering them the most competitive material in the next-generation ICs technology.However,certain challenges impede the industrialization of CNTs,particularly in terms of material preparation,which significantly hinders the development of CNT-based ICs.Focusing on CNT-based ICs technology,this review summarizes its main technical status,development trends,existing challenges,and future development directions.展开更多
We study the closed range property and the strict singularity of integration operators acting on the spaces F(p,pα-2,s).We completely characterize the closed range property of the Volterra companion operator I_(g)on ...We study the closed range property and the strict singularity of integration operators acting on the spaces F(p,pα-2,s).We completely characterize the closed range property of the Volterra companion operator I_(g)on F(p,pα-2,s),which generalizes the existing results and answers a question raised in[A.Anderson,Integral Equations Operator Theory,69(2011),no.1,87-99].For the Volterra operator J_(g),we show that,for 0<α≤1,J_(g)never has a closed range on F(p,pα-2,s).We then prove that the notions of compactness,weak compactness and strict singularity coincide in the case of J_(g)acting on F(p,p-2,s).展开更多
Evidences show that electric fields(EFs)induced by the magnetic stimulation could modulates brain activities by regulating the excitability of GABAergic interneuron.However,it is still unclear how and why the EF-induc...Evidences show that electric fields(EFs)induced by the magnetic stimulation could modulates brain activities by regulating the excitability of GABAergic interneuron.However,it is still unclear how and why the EF-induced polarization affects the interneuron response as the interneuron receives NMDA synaptic inputs.Considering the key role of NMDA receptor-mediated supralinear dendritic integration in neuronal computations,we suppose that the applied EFs could functionally modulate interneurons’response via regulating dendritic integration.At first,we build a simplified multi-dendritic circuit model with inhomogeneous extracellular potentials,which characterizes the relationship among EF-induced spatial polarizations,dendritic integration,and somatic output.By performing model-based singular perturbation analysis,it is found that the equilibrium point of fast subsystem can be used to asymptotically depict the subthreshold input–output(sI/O)relationship of dendritic integration.It predicted that EF-induced strong depolarizations on the distal dendrites reduce the dendritic saturation output by reducing driving force of synaptic input,and it shifts the steep change of sI/O curve left by reducing stimulation threshold of triggering NMDA spike.Also,the EF modulation prefers the global dendritic integration with asymmetric scatter distribution of NMDA synapses.Furthermore,we identify the respective contribution of EF-regulated dendritic integration and EF-induced somatic polarization to an action potential generation and find that they have an antagonistic effect on AP generation due to the varied NMDA spike threshold under EF stimulation.展开更多
Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors(TFs)in intricate regulatory networks in a cell-type specific manner.Here we...Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors(TFs)in intricate regulatory networks in a cell-type specific manner.Here we introduced a comprehensive single-cell transcriptomic atlas of Arabidopsis seedlings.This atlas is the result of meticulous integration of 63 previously published scRNA-seq datasets,addressing batch effects and conserving biological variance.This integration spans a broad spectrum of tissues,including both below-and above-ground parts.Utilizing a rigorous approach for cell type annotation,we identified 47 distinct cell types or states,largely expanding our current view of plant cell compositions.We systematically constructed cell-type specific gene regulatory networks and uncovered key regulators that act in a coordinated manner to control cell-type specific gene expression.Taken together,our study not only offers extensive plant cell atlas exploration that serves as a valuable resource,but also provides molecular insights into gene-regulatory programs that varies from different cell types.展开更多
文摘A sample of 76 older adults (27 with diabetes and 49 without diabetes) were selected to judge three information factors, metamemory related to—drug organization—stress and physical activity in relation to their perception of self-care. In order to do so, an Integration Information Theory was considered to determine systematic cognitive algebra rules underlying judgment about 24 different health self-care scenarios. Results indicate that older adults without diabetes use a summative cognitive rule to integrate relevant health information but older adults with diabetes do not. Both groups agreed that metamemory was the most relevant factor to their self-care followed by stress and physical activity. However, valuation of these factors does depend on the type of group. Implications of these results to healthcare a behavioral nursing intervention are discussed in this paper.
文摘In the process industry, automation and process control systems are widely implemented, information integration is however far away from satisfactory. It remains a hard job for senior managers to make decisions based on the plant-wide real-time integrated information. This paper proposes a multi-layer information integration platform. In the data integration level, the standard for the exchange of product (STEP) and the extensible markup language (XML) are used to unify these data of the chemical process. In the model integration level, the models are integrated by using the neutral model repository and CAPE-OPEN. In the integration of process task, the common object request broker architecture (CORBA) is used as the communication mediator. The XML is taken as the data standard. A uniform information platform is thus constructed and realized. The proposed information integration platform is satisfactorily implemented to solve the Tennessee Eastman (TE) problem.
基金This work was supported in part by the National Science Fund for Distinguished Young Scholars in China under grant 61425012the National Science Foundation Project in China under grant 61931005 and 61731017.
文摘Mobile communication standards have been developed into a new era of B5G and 6G.In recent years,low earth orbit(LEO)satellites and space Internet have become hot topics.The integrated satellite and terrestrial systems have been widely discussed by industries and academics,and even are expected to be applied in those huge constellations in construction.This paper points out the trends of two stages towards system integration of the terrestrial mobile communication and the satellite communications:to be compatible with 5G,and to be integrated within 6G.Based on analysis of the challenges of both stages,key technologies are thereafter analyzed in detail,covering both air interface currently discussed in 3GPP for B5G and also novel network architecture and related transmission technologies toward future 6G.
基金The National Natural Science Foundation of China (No.50305007)the Scientific Research Project of Hubei Provincial Department of Education (No.D200618003)
文摘Ontology-based semantic information integration resolve the schema-level heterogeneity and part of data level heterogeneity between distributed data sources. But it is ubiquitous that schema semantics of information is identical while the interpretation of it varies with different context, and ontology-based semantic information integration can not resolve this context heterogeneity. By introducing context representation and context mediation to ontology based information integration, the attribute-level context heterogeneity can be detected and reconciled automatically, and hence a complete solution for semantic heterogeneity is formed. Through a concrete example, the context representation and the process in which the attribute-level context heterogeneity is reconciled during query processing are presented. This resolution can make up the deficiency of schema mapping based semantic information integration. With the architecture proposed in this paper the semantic heterogeneity solution is adaptive and extensive.
基金Project(2001CB409809) supported by the National Key Foundmental Research and Development Program of Chinaproject(1042610) supported by the Key Program of the Education Ministry of China
文摘Prediction has become more and more difficult in mineral exploration, especially in the mature exploration environment such as Tongling copper district. For enhancing predictive discovery of hidden ore deposits in such mature environment, the key strategies which should be adopted include the innovation of the exploration models, application of the advanced exploration techniques and integration of multiple sets of information. The innovation of the exploration models should incorporate the new metallogenic concepts that are based on the geodynamic anatomization. The advanced techniques applied in the mature exploration environment should aim at the speciality and complexity of the geological setting and working environments. The information synthesis is to integrate multiple sets of data for giving a more credible and visual prospectivity map by using the geographic imformation system(GIS) and several mathematical methods, such as weight of evidence and fuzzy logic, which can extract useful information from every set of data as much as possible. Guided by these strategies, a predictive exploration in Fenghuangshan ore field of Tongling copper district was implemented, and a hidden ore deposit was discovered.
文摘This paper analyzes the flow of the process design an d the fountain of the technique data in a manufacturing enterprise, and discusse s the information flows between CAPP and other systems in CIMS, such as CAD syst em and Enterprise Resource Planning (ERP) system. And then, it discusses the pla ns of information integration between CAPP and CAD, as well as between CAPP and ERP. To design the processes of a product requires the manufacture information, such as blank material and machine tool, which is saved in a database in ERP. General ly, a traditional CAPP system considers the information of the manufacturing res ources, such as machine tool, as changeless. However, it is real changing, becau se the resources may be occupied or the machine tool may be under repair. Theref ore, in order to design the processes more reasonably, we must consider the real change of resources in a workshop. Creating a public resource database to suppo rt the real change of resources is put forward in this paper. With the public re source database, the resource integration between CAPP system and ERP is realize d; and by information collections in CAPP system, such as BOM, the material cons umption and man-hour consumption and their output to ERP, the information integ ration between CAPP system and ERP is realized.
基金Supported by the Natural Science Foundation of China( No.5 9885 0 0 4,5 9990 470 )
文摘A new information integration platform for computer integrated manufacturing system (CIMS) is presented, which is based on agent and CORBA. CORBA enhances the system integration because it is an industry-standard for interoperable, distributed objects across heterogeneous hardware and software platform. Agent technology is used to improve intelligence of integration system. In order to implement the information integration platform, we use network integration server to integrate network, design a generic database agent to integrate database, adopt multi-agent based architecture to integrate application, and utilize wrapper as CORBA object to integrate legacy code.
文摘A combined approach of thermodynamic analysis and mixed-integer linear programming is presented for performing structural and parameter optimization in the integration of energy system of chemical processes. Tnermodynamic analysis is used to set up a superstructure configuration of energy system in order to reduce the space of search. The application of the combined approach is illustrated by a revamping integration of a large existing energy system in a refinery complex.
基金National Key Technology R&D Program in the 12th Five Year Plan of China (No. 2011BAB10B06)Independent Innovation Foundation of Tianjin University (No. 1102119)
文摘The theory and method of system integration for the real-time monitoring of core rock-fill dam filling con- struction quality are studied in this paper. First, the importance analysis of system integration factors is carried out with the analytic hierarchy process. Then, according to the analysis result of integration factors, the conceptual model of system integration is built based on function integration, index integration, technology integration and information integration, the index structure of core rock-fill dam filling construction quality control is constructed and the method of function integration and technology integration is studied. The mathematical model of process monitoring is built according to monitoring objective, process and indexes. Research results have been applied in Nuozhadu core rock-fill dam construction management, realizing system integration through building appropriate monitoring work flow and comprehensive information platform of digital dam.
文摘Datong-Qinhuangdao line, as the first electrified double-track heavy-haul line dedicated to coal transport in China, extends from Datong in the west, and reaches Qinhuangdao in the east, opened to traffic in December, 1992, totaling 653 km with the designed annual traffic volume of 1×108 t. In order to meet the demands of national economic development, the transport capacity of the line must be enhanced greatly. Depending on independent innovation, MOR, for the first time in the world,realizes the integration between GSM-R and Locotrol, the integration between 800 MHz digital radio and Locotrol, and the integration between a single set of Locotrol and SS4 locomotive. Meanwhile, CR develops equipment portfolio for heavy-haul through combining 2 high power locomotives of HXD series (means harmony) with controllable EOT. Relying on integration and innovation, it succeeds in operating 20 kt-level combined heavy-haul train on Datong-Qinhuangdao line, which tripled the annual traffic volume of the line from 1×108 t in 2002 to 3×108 t in 2007.
文摘BACKGROUND Sensory integration intervention is highly related to the child's effective interaction with the environment and the child's development.Currently,various sensory integration interventions are being applied,but research methodological problems are arising due to unsystematic protocols.This study aims to present the optimal intervention protocol by presenting scientific standards for sensory integration intervention through meta-analysis.AIM To prove the effectiveness of sensory integration therapy,examine the latest trend of sensory integration studies in Korea,and provide clinical evidence for sensory integration therapies.METHODS The database of Korean search engines,including RISS,KISS,and DBpia,was used to search for related literature published from 2001 to October 2020.The keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this search.Then,a meta-analysis was conducted on 24 selected studiesRISS,KISS,and DBpia,was used to search for related literature published from 2001 to October 2020.The keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this search.Then,a meta-analysis was conducted on 24 selected studies.RESULTS Sensory integration intervention has been proven effective in children with cerebral palsy,autism spectrum disorder,attention deficit/hyperactivity disorder,developmental disorder,and intellectual disability in relation to the diagnosis of children.Regarding sensory integration therapies,1:1 individual treatment with a therapist or a therapy session lasting for 40 min was most effective.In terms of dependent variables,sensory integration therapy effectively promoted social skills,adaptive behavior,sensory processing,and gross motor and fine motor skills.CONCLUSION The results of this study may be used as therapeutic evidence for sensory integration intervention in the clinical field of occupational therapy for children,and can help to present standards for sensory integration intervention protocols.
文摘The rapid development of information technology provides a new opportunity and impetus for the reform of education and teaching.Deep integration of information technology and education and teaching is the only way to promote the modernization of education.Starting from the connotation of the deep integration of information technology and education and teaching,this paper analyzes the existing problems in the current integration process,and puts forward innovative strategies from the aspects of concept,resources,model,and evaluation.Through measures such as building a smart teaching environment,enriching high-quality teaching resources,innovating teaching organization models,and establishing multiple evaluation systems,we will realize the deep integration of information technology and teaching,promote the reform of teaching and learning methods,improve the quality of personnel training,and provide strong support for the modernization of education.
基金Jiangsu Province Vocational Education Teaching Reform Research Project“Construction and Application of Digital Teaching Factory Under the Background of Integration of Production and Education-A Case Study of Chemical Engineering Majors in Vocational Colleges”(ZYB141)Center for Scientific Research and Development in Higher Education Institutes,Ministry of Education 2022“Virtual Simulation Technology in Vocational Education and Teaching Innovation Application”Special Project(ZJXF2022320)。
文摘With the development of the integration of production and education,chemical engineering and technology education is facing many new challenges and opportunities.The construction of a chemical virtual simulation practice teaching system under the background of integration of production and education aims to improve students’learning efficiency and innovation ability with the help of virtual simulation technology,so as to meet the needs of future industrial development.This paper discusses the significance of the construction of the system,analyzes the difficulties and challenges that may be encountered in the construction process,and evaluates the effective strategies to strengthen the construction of the system.Through the introduction of virtual simulation technology,students can improve their practical skills and innovation ability,and better adapt to the development needs of industrialization and informatization.
基金supported by the Swiss National Science Foundation(Grant No.189882)the National Natural Science Foundation of China(Grant No.41961134032)support provided by the New Investigator Award grant from the UK Engineering and Physical Sciences Research Council(Grant No.EP/V012169/1).
文摘In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM formulation.To mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing technique.By discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the PFEM.We express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)problem.Stresses,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point method.Consequently,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM formulation.Numerical experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM approaches.This work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.
基金Project supported in part by the National Key Research and Development Program of China(Grant No.2021YFB2206504)the National Natural Science Foundation of China(Grant No.62235017)the China Postdoctoral Science Foundation(Grant No.2021M703125).
文摘The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which not only provides the optical gain which is absent from native Si substrates and enables complete photonic functionalities on chip,but also improves the system performance through advanced heterogeneous integrated packaging.This paper reviews recent progress of silicon-based optoelectronic heterogeneous integration in high performance optical interconnection.The research status,development trend and application of ultra-low loss optical waveguides,high-speed detectors,high-speed modulators,lasers and 2D,2.5D,3D and monolithic integration are focused on.
基金supported by National Natural Science Foundation of China(Grant No.52022078)Shaanxi Provincial Key Research and Development Program(Grant No.2021ZDLGY10-02,2019ZDLGY01-09)。
文摘As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning carbon-based semiconductor technology has become one of the most disruptive technologies in the post-Moore era.As one-dimensional nanomaterials,carbon nanotubes(CNTs)are far superior to silicon at the same technology nodes of FETs because of their excellent electrical transport and scaling properties,rendering them the most competitive material in the next-generation ICs technology.However,certain challenges impede the industrialization of CNTs,particularly in terms of material preparation,which significantly hinders the development of CNT-based ICs.Focusing on CNT-based ICs technology,this review summarizes its main technical status,development trends,existing challenges,and future development directions.
基金partially supported by the Fundamental Research Funds for the Central Universities(GK202207018)of China。
文摘We study the closed range property and the strict singularity of integration operators acting on the spaces F(p,pα-2,s).We completely characterize the closed range property of the Volterra companion operator I_(g)on F(p,pα-2,s),which generalizes the existing results and answers a question raised in[A.Anderson,Integral Equations Operator Theory,69(2011),no.1,87-99].For the Volterra operator J_(g),we show that,for 0<α≤1,J_(g)never has a closed range on F(p,pα-2,s).We then prove that the notions of compactness,weak compactness and strict singularity coincide in the case of J_(g)acting on F(p,p-2,s).
基金Project supported by the National Natural Science Foundation of China(Grant No.62171312)the Tianjin Municipal Education Commission Scientific Research Project,China(Grant No.2020KJ114).
文摘Evidences show that electric fields(EFs)induced by the magnetic stimulation could modulates brain activities by regulating the excitability of GABAergic interneuron.However,it is still unclear how and why the EF-induced polarization affects the interneuron response as the interneuron receives NMDA synaptic inputs.Considering the key role of NMDA receptor-mediated supralinear dendritic integration in neuronal computations,we suppose that the applied EFs could functionally modulate interneurons’response via regulating dendritic integration.At first,we build a simplified multi-dendritic circuit model with inhomogeneous extracellular potentials,which characterizes the relationship among EF-induced spatial polarizations,dendritic integration,and somatic output.By performing model-based singular perturbation analysis,it is found that the equilibrium point of fast subsystem can be used to asymptotically depict the subthreshold input–output(sI/O)relationship of dendritic integration.It predicted that EF-induced strong depolarizations on the distal dendrites reduce the dendritic saturation output by reducing driving force of synaptic input,and it shifts the steep change of sI/O curve left by reducing stimulation threshold of triggering NMDA spike.Also,the EF modulation prefers the global dendritic integration with asymmetric scatter distribution of NMDA synapses.Furthermore,we identify the respective contribution of EF-regulated dendritic integration and EF-induced somatic polarization to an action potential generation and find that they have an antagonistic effect on AP generation due to the varied NMDA spike threshold under EF stimulation.
基金supported by the National Natural Science Foundation of China (No.32070656)the Nanjing University Deng Feng Scholars Program+1 种基金the Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions,China Postdoctoral Science Foundation funded project (No.2022M711563)Jiangsu Funding Program for Excellent Postdoctoral Talent (No.2022ZB50)
文摘Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors(TFs)in intricate regulatory networks in a cell-type specific manner.Here we introduced a comprehensive single-cell transcriptomic atlas of Arabidopsis seedlings.This atlas is the result of meticulous integration of 63 previously published scRNA-seq datasets,addressing batch effects and conserving biological variance.This integration spans a broad spectrum of tissues,including both below-and above-ground parts.Utilizing a rigorous approach for cell type annotation,we identified 47 distinct cell types or states,largely expanding our current view of plant cell compositions.We systematically constructed cell-type specific gene regulatory networks and uncovered key regulators that act in a coordinated manner to control cell-type specific gene expression.Taken together,our study not only offers extensive plant cell atlas exploration that serves as a valuable resource,but also provides molecular insights into gene-regulatory programs that varies from different cell types.