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Discussion on Improvement of Toxicological Pathology Study
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作者 Ren Jin(Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, CAS, Shanghai 200031) 《Science Foundation in China》 CAS 2003年第1期31-34,共4页
Toxicological pathology plays a key role in drug safety assessment. To enhance the research level of toxicological pathology, the following stud-ies should be carried out urgently: setting up a standard operation proc... Toxicological pathology plays a key role in drug safety assessment. To enhance the research level of toxicological pathology, the following stud-ies should be carried out urgently: setting up a standard operation procedure (SOP) for toxico-logical pathology assessment; emphasizing on immunotoxicology evaluation; adopting a new ex-periment model of replacement, featuring high speed and reliability; introducing new techniques and new models in toxicological mechanism re-search; and establishing a new appraisal system to screen innovative drug and rapid and high pre-cision methods for early security assessment, de-tection and measurement. 展开更多
关键词 drag safety assessment toxicological pathology immunotoxicology evaluation short-term replacement model highthroughput toxicology
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