Introduction: Malaria is an important disease, causing high morbidity and mortality, especially in Sub-Saharan Africa. Measuring malaria prevalence using malaria rapid diagnostic tests (mRDTs), particularly among a vu...Introduction: Malaria is an important disease, causing high morbidity and mortality, especially in Sub-Saharan Africa. Measuring malaria prevalence using malaria rapid diagnostic tests (mRDTs), particularly among a vulnerable population sub-group, is a vital public health step in discovering effective methods of prevention and control. This study set out to examine the association between “place” and other risk factors with malaria prevalence among Batwa Indigenous People (IP). Methods: An analytical cross-sectional study design was implemented. Two surveys January 2014 (n = 572) and April 2014 (n = 541) involving interviews and testing for malaria using mRDTs were conducted in 10 Batwa settlements where a total of 1113 Batwa of all ages were surveyed and tested. The data were first compiled in MS Excel and then imported and analyzed using STATA ver.14. Descriptive statistics, were generated, followed by bivariable and multivariable regression model analysis to establish associations between the predictor and outcome variables with p ≤ 0.05 considered statistically significant. Results: Overall prevalence was 13.94% (n = 146). There is a significant relationship between settlement (place) and malaria prevalence AOR 11.7, 95% CI (1.38 - 98.93), p-value = 0.02. More males 16.97% (n = 84) tested positive compared to females 11.23% (n = 62) but there was no statistically significant association between gender and mRDT (p-value > 0.005). Children less than 5 years registered high prevalence and there was a significant relationship between age and mRDT (p-value ≤ 0.005). Wealth proxy indicators showed no association with prevalence p-value = 0.390. Season had no association with prevalence (p-value = 0.80). However, the proportion of the day spent in the forest/woodlands was significantly associated with malaria prevalence COR 12.83, 95% CI (1.14 - 143.73) p-value = 0.04. Low elevation was significantly associated with malaria prevalence COR 2.42, 95% CI (1.32 - 4.41), p = 0.004 but sleeping under a net and level of education did not show any association with malaria prevalence. Conclusion: This study highlights the importance of place in predicting malaria prevalence among Batwa Indigenous People a marginalized and remortely located sub-population. This study has shown that place matters in determining malaria prevalence. However, other factors like age, elevation and gender also contribute to malaria prevalence. Batwa have higher prevalence than the national and even non-indigenous populations in the same district. We recommend targeting hotspots intervention approach since it has proven reasonable impact on reducing malaria prevalence.展开更多
Objective:To investigate the differences in risk factors and prognosis between young and elderly patients with acute ST-segment elevation myocardial infarction(STEMI)so as to provide a basis for the prevention of youn...Objective:To investigate the differences in risk factors and prognosis between young and elderly patients with acute ST-segment elevation myocardial infarction(STEMI)so as to provide a basis for the prevention of young patients with acute STEMI.Methods:Patients initially diagnosed with STEMI in the 920"Hospital of Joint Logistic Support Force of PLA from January 1,2018 to December 31,2022 were retrospectively enrolled in this study.A total of 235 STEMI patients aged≤45 years old and 532 STEMI patients aged≥65 years old were screened.The baseline characteristics,laboratory indicators,clinical characteristics,coronary angiography,SYNTAX score and major adverse cardiovascular events(MACE)during 1-year follow-up were analyzed and compared.Results:A total of 767 STEMI patients were enrolled,including 235 in the young group and 532 in the elderly group.Among the STEM patients in the young group,224 cases were male,and smoking and drinking were common.Compared with the elderly group,the young group had shorter hospital stays and more family history of ischemic heart disease(IHD).The level of low-density lipoprotein in the young group was higher than that in the old group,while the level of high-density lipoprotein in the young group was lower than that in the old group.The level of high uric acid and homocysteine in the young group was significantly higher than that in the old group.The main cause of STEMI in the young group was fatigue,and the most common symptom was angina pectoris.Coronary angiography showed that single vessel disease was more common in the young group than in the elderly group,and the lesion in the young group was the left anterior descending artery.The SYNTAX score was significantly lower in the young group than in the elderly group according to the anatomical characteristics of coronary artery disease.In the forest plot,diabetes mellitus and a family history of IHD showed a trend of major adverse cardiovascular events(MACE)in both groups.Conclusion:Males,smokers,alcohol drinkers and family history of ischemic heart disease are more common in young patients.Common risk factors include fatigue,hyperuricemia,hyperlipidemia and so on.In addition,age itself is an independent risk factor.Management of diabetes,hyperuricemia,and homocysteine levels is essential to reduce the incidence of cardiovascular events in young patients.By controlling these factors,the incidence of young patients with acute STEMI can be effectively prevented and the corresponding prevention and treatment basis can be provided.展开更多
In order to investigate the association of fibrin monomer polymerization function (FMPF) with traditional cerebrovascular risk factors and ischemic cerebrovascular disease in old people. 1∶1 paired case-control compa...In order to investigate the association of fibrin monomer polymerization function (FMPF) with traditional cerebrovascular risk factors and ischemic cerebrovascular disease in old people. 1∶1 paired case-control comparative study was performed for FMPF and traditional cerebrovascular risk factors on 110 cases of old ischemic cerebrovascular disease and 110 controls matched on age, sex and living condition. The results showed that cerebrovascular risk factors were more prevalent in case group than in control group. In the case group, FMPF was significantly higher than in control group. There was a significant positive correlation between hypertension and fibrin monomer polymerization velocity (FMPV), hypertension and fibrinogen (Fbg), alcohol consumption and Fbg, but no significant correlation between diabetic mellitus, smoking and FMPF was found. Among the parameters of blood lipids, there were significant positive correlations between total cholesterol (TC) and parameters of FMPF to varying degrees, triglycerides (TG) and FMPV, TG and Fbg. Our results also showed there were significant linear trends between TC and FMPV (P<0. 001), TC and Fbg (P=0. 0087), TG and FMPV/Amax (maximum absorbance)(P=0. 0143) respectively. Multiple logistic regression analysis revealed that FMPF in case group remained significantly higher than control group after adjustment of all risk factors that were significant in univariate analysis. It was concluded that there is a possible pathophysiological link between FMPF and cerebrovascular risk factors. An elevated FMPF is associated with ischemic cerebrovascular disease and an independent risk factor of this disease. In old people, detection of FMPF might be a useful screening to identify individuals at increased cerebrothrombotic risk.展开更多
Aims: to analyze the presence and simultaneity of behavioral risk factors for chronic non-communicable disease (NCD) in adults and the elderly. Methods: quantitative, cross-sectional and observational study. Healthy a...Aims: to analyze the presence and simultaneity of behavioral risk factors for chronic non-communicable disease (NCD) in adults and the elderly. Methods: quantitative, cross-sectional and observational study. Healthy and unhealthy eating are classified according to the frequency of food consumption. Smoking is expressed by the percentage of smokers. Harmful alcohol consumption by the percentage of individuals who consumed alcoholic beverages at least once in the last 30 days. Classification of the level of physical inactivity required to practice at least 150 minutes of physical activity. Results: the sample constituted 719 people, 535 adults and 184 elderly. The behavioral risk factor reported by most adults 499 (93.3%) and elderly 156 (84.8%) was unhealthy eating. Frequency 72% higher of smoking, four times higher of harmful alcohol consumption and 10% higher of unhealthy food among adults when compared to the elderly. The simultaneity between risk factors was 39% greater in adults than in the elderly. Discussion: risk factors evaluated in this study are key aspects of the development of NCDs. Adults have 2.43 times the chance of presenting two risk factors and 7.73 times the chance of presenting three in relation to the elderly. Conclusion: To achieve more effective and differentiated results, knowing and directing measures to control behavioral risk factors, whether isolated or concurrent, requires specific knowledge.展开更多
Objective: To evaluate the association of socio-demographic and clinical characteristics, and risk factors with occurrence of pressure ulcers in institutionalized elderly people. Method: This cross-sectional, analytic...Objective: To evaluate the association of socio-demographic and clinical characteristics, and risk factors with occurrence of pressure ulcers in institutionalized elderly people. Method: This cross-sectional, analytical study, in quantitative approach, performed from the database analysis linked to the project “Pressure Ulcer in institutionalized elderly people: Association of incidence with the risk factors to functional and nutritional assessment” developed in six long-stay institutions for the elderly people in João Pessoa. Data were analyzed using the Statistical Package for Social Sciences (SPSS) version 20.0. Associations were made through chi square test and Odds Ratio. Results: The clinical conditions of significant associations with the occurrence of pressure ulcers were the variables neurological disorders (p = 0.011) and visual impairment (p = 0.005). As for risk factors, the most important was fecal incontinence (p Conclusion: The analysis of the associations pointed out problems that require intervention in order to prevent health implications of the elderly people and to minimize the risk and occurrence of this injury.展开更多
Objective This study aimed to explore the roles of three common single nucleotide polymorphisms in the X-ray repair cross-complementing group-1 gene (XRCC1) and of life style factors and their possible interactions ...Objective This study aimed to explore the roles of three common single nucleotide polymorphisms in the X-ray repair cross-complementing group-1 gene (XRCC1) and of life style factors and their possible interactions in the risk of esophageal squamous cell carcinoma (ESCC) in China. Methods A population-based case-control study of 432 cases and 915 controls was conducted in Yangzhong County, Jiangsu Province, China. Subjects were interviewed by trained interviewers using a structured questionnaire that included questions on demographics and life style. XRCC1 genotypes were analyzed using a polymerase chain reaction based restriction fragment length polymorphism (PCR-RFLP) assay. Unconditional logistic regression analysis was used to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for associations of ESCC with XRCCI polymorphisms and lifestyle-related factors. Results Both the drinking of river water and alcohol intake history were significantly associated with an increased risk of ESCC among men with aORs of 4.20 (95% Ch 2.90-6.07) and 2.03 (95% Ch 1.43-2.89), respectively. For women, the corresponding odds ratios were 8.37 (95% CI: 5.09-13.75) for river water drinking and 12.78 (95% CI: 2.69-60.69) for long-term stored rice intake. After the XRCC1 G28152A polymorphism was adjusted for potential confounders, subjects with GA and AA genotypes had an increased risk for ESCC (aOR: 1.21, 95% CI: 0.93-1.56), compared with subjects with a GG genotype, and a positive multiplicative interaction between intake of long-term stored rice and the XRCC1 G28152A polymorphism was observed (P=O.009).Conclusions Our findings suggest that both lifestyle-related factors, including drinking river water, long-term stored rice and alcohol intake, and the XRCC1 G28152A polymorphism were possible risk factors for ESCC, and that the XRCC1 G28152A polymorphism modified the effect of long-term stored rice intake on the risk of ESCC among Chinese people.展开更多
Objective: To study the relevant risk factors of polycystic ovarian syndrome(PCOS) of Li People so as to provide basis for early diagnosis and treatment of PCOS. Methods: With casecontrol study method, 285 cases of PC...Objective: To study the relevant risk factors of polycystic ovarian syndrome(PCOS) of Li People so as to provide basis for early diagnosis and treatment of PCOS. Methods: With casecontrol study method, 285 cases of PCOS of Li People were as recruited case group, and 580 cases of non-PCOS of female Li People as control group. Questionnaire was adopted to collect data regarding risk factors of PCOS, then the risk factors of PCOS was searched by univariate and multivariate analysis. Results: Multivariate analysis showed that the risk factors of PCOS included in menstrual cycle disorder(OR=5.824), bad mood(OR=2.852), family history of diabetes(OR=7.008), family history of infertility(OR=11.953), menstrual irregularity of mother(OR=2.557) and lack of physical exercise(OR=1.866). Conclusions: To target the high risk factors of menstrual cycle disorder, family history of diabetes, family history of infertility, family history of diabetes, bad mood and lack of physical exercise of female population, we should implement early screen, diagnose and treatment of POCS in order to reduce the incidence rate of PCOS and improve prognosis of PCOS.展开更多
Plant mitochondrial phosphate transporters regulate phosphate transport and ATP synthesis. Determining whether they function in abiotic stress response process would shed light on their response to salt stress. We use...Plant mitochondrial phosphate transporters regulate phosphate transport and ATP synthesis. Determining whether they function in abiotic stress response process would shed light on their response to salt stress. We used the CRISPR/Cas9 gene-editing system to mutagenize two mitochondrial phosphate transporters, OsMPT3;1 and OsMPT3;2, to investigate their regulatory roles under salt stress. Two cas9(CRISPR-associated protein9)-free homozygous mutants, mpt33 and mpt30, were confirmed to be stable. Both OsMPT3;1 and OsMPT3;2 were markedly induced by salt stress, and their mutagenesis strongly inhibited growth and development, especially under salt stress. Mutagenesis sharply reduced the accumulation of ATP, phosphate, calcium, soluble sugar, and proline and increased osmotic potential, malondialdehyde, and Na^+ /K^+ ratio under salt stress. Both mutants demonstrate normal growth and development in the presence of ATP, revealing high sensitivity to exogenous ATP under salt stress. The mutants showed lowered rates of Na^+ efflux but also of K^+ and Ca^(2+) influx under salt stress. Mutagenesis of OsMPT3;2 altered the enrichment profiles of differentially expressed genes involved mainly in synthesis of secondary metabolites, metabolism of glycolysis, pyruvate, tricarboxylic acid cycle, in response to salt stress. The mutant displayed significant accumulation differences in 14 metabolites involved in 17 metabolic pathways, and strongly up-regulated the accumulation of glutamine, a precursor in proline synthesis, under salt stress. These findings suggest that the OsMPT3 gene modulates phosphate transport and energy supply for ATP synthesis and triggers changes in accumulation of ions and metabolites participating in osmotic regulation in rice under salt stress, thus increasing rice salt tolerance. This study demonstrates the effective application of CRISPR/Cas9 gene-editing to the investigation of plant functional genes.展开更多
This paper examines the impact of key economic factors on trade volumes between China and the Regional Comprehensive Economic Partnership(RCEP)member states.Studies have shown that gross domestic products(GDP),exchang...This paper examines the impact of key economic factors on trade volumes between China and the Regional Comprehensive Economic Partnership(RCEP)member states.Studies have shown that gross domestic products(GDP),exchange rate,and inflation have an impact on China’s import and export trade volume with RCEP member states.China’s export trade volume to RCEP member states is deeply affected by China’s GDP,but the import trade volume depends on China’s domestic demand and market.The impact of exchange rates on import and export trade volumes varies from country to country.China’s export volume to RCEP member states is generally more affected by the consumption level of its residents than the consumption level of Chinese residents.展开更多
Qimin Yaoshu( Important Arts for the People's Welfare) made a detailed record of the diet and its production methods in the middle and lower reaches of the Yellow River during the Wei Dynasty.Hu foods are importan...Qimin Yaoshu( Important Arts for the People's Welfare) made a detailed record of the diet and its production methods in the middle and lower reaches of the Yellow River during the Wei Dynasty.Hu foods are important parts in the book.Hu foods recorded in Important Arts for the People's Welfare mainly include cheese products,cake products,and dish products.These contents not only reflect the exchange of diet culture between different nationalities in the middle and lower reaches of the Yellow River during this period,but also reflect the breadth and depth of ethnic exchanges and integration in this period.展开更多
Diaolou style building is an important residential building of Qiang people. In recent years, Qiang people’s own cultural identities and behavioral awareness have transformed. Due to the lack of attention to the inhe...Diaolou style building is an important residential building of Qiang people. In recent years, Qiang people’s own cultural identities and behavioral awareness have transformed. Due to the lack of attention to the inheritance of original architectural style and the absence of a detailed scientific protection of the landscape, the architectural style of Diaolou style building gradually loses its vitality. It is difficult to control and guide it effectively. And tourism economy which enjoys a direct link with the architecture has been confined to further development. From the perspective of behavioral science, this study innovatively analyzes the Diaolou style building of Qiang people by combining the methodology of Lew in metal of behavior and Analytic Hierarchy Process. Firstly, 32 symbols are chosen as Diaolou architectural style factors from the selection of more than 100 Diaolou architectural decorative symbols. Then by measuring their weight coefficients through the Analytic Hierarchy Process, eight main style factors have been screened out. After field research, we analyze the actual use of the style factors of the six typical villages such as Gina. On this basis, this paper analyzes the behavioral factors of Diaolou style building of Qiang people, deconstructs its use and puts forward a concept which takes style control as a guidance and behavior guidance as a strategy to protect and develop Diaolou style building of Qiang people. It is also proposed that a control and guidance strategy of inheritance and development of Qiang Diaolou architectural style, including master the influencing factors as a whole, follow the principle of people-oriented, compound function, dynamic development and highlighting national aesthetics, based on its style system, and grasp the trend of architectural style, etc. The study provides an effective guarantee for the further development of rural tourism, and a necessary theoretical and technical guidance for the government to adopt targeted steps.展开更多
This paper is based on the partnership between China’s higher vocational colleges and industry, and obtains a large number of data on industry-college partnerships through case analysis, interviews and questionnaires...This paper is based on the partnership between China’s higher vocational colleges and industry, and obtains a large number of data on industry-college partnerships through case analysis, interviews and questionnaires. This paper analyzes the main factors that affect industry-college partnerships and the current problems and challenges, then puts forward the solutions.展开更多
This investigation assessed the efficacy of 10 widely used machine learning algorithms(MLA)comprising the least absolute shrinkage and selection operator(LASSO),generalized linear model(GLM),stepwise generalized linea...This investigation assessed the efficacy of 10 widely used machine learning algorithms(MLA)comprising the least absolute shrinkage and selection operator(LASSO),generalized linear model(GLM),stepwise generalized linear model(SGLM),elastic net(ENET),partial least square(PLS),ridge regression,support vector machine(SVM),classification and regression trees(CART),bagged CART,and random forest(RF)for gully erosion susceptibility mapping(GESM)in Iran.The location of 462 previously existing gully erosion sites were mapped through widespread field investigations,of which 70%(323)and 30%(139)of observations were arbitrarily divided for algorithm calibration and validation.Twelve controlling factors for gully erosion,namely,soil texture,annual mean rainfall,digital elevation model(DEM),drainage density,slope,lithology,topographic wetness index(TWI),distance from rivers,aspect,distance from roads,plan curvature,and profile curvature were ranked in terms of their importance using each MLA.The MLA were compared using a training dataset for gully erosion and statistical measures such as RMSE(root mean square error),MAE(mean absolute error),and R-squared.Based on the comparisons among MLA,the RF algorithm exhibited the minimum RMSE and MAE and the maximum value of R-squared,and was therefore selected as the best model.The variable importance evaluation using the RF model revealed that distance from rivers had the highest significance in influencing the occurrence of gully erosion whereas plan curvature had the least importance.According to the GESM generated using RF,most of the study area is predicted to have a low(53.72%)or moderate(29.65%)susceptibility to gully erosion,whereas only a small area is identified to have a high(12.56%)or very high(4.07%)susceptibility.The outcome generated by RF model is validated using the ROC(Receiver Operating Characteristics)curve approach,which returned an area under the curve(AUC)of 0.985,proving the excellent forecasting ability of the model.The GESM prepared using the RF algorithm can aid decision-makers in targeting remedial actions for minimizing the damage caused by gully erosion.展开更多
As the population ages, older people's health and quality of life are becoming a matter of public concern increasingly. Through review of the literatures and analysis of the reasons for falls in older people, we w...As the population ages, older people's health and quality of life are becoming a matter of public concern increasingly. Through review of the literatures and analysis of the reasons for falls in older people, we worked out some measures to cope with such a situation, provided the self-care knowledge of falls prevention for older people and improved the quality life of older persons. The recovery process is long, if the old people fall down, which brings a lot of inconvenience to individuals and families, and it can also cause a lot of complications. If wary of fall risk factors, the quality of life of older persons can be improved. According to the different conditions of the elderly, we should take effective measures to create suitable living environment for senior citizens, and propagandize the knowledge of the old people's health care, which has the great significance in preventing the elderly's fall, and improving their living quality.展开更多
A developing country like Rwanda heavily </span><span style="font-family:Verdana;">is </span><span style="font-family:Verdana;">keen </span><span style="font-f...A developing country like Rwanda heavily </span><span style="font-family:Verdana;">is </span><span style="font-family:Verdana;">keen </span><span style="font-family:Verdana;">on</span><span style="font-family:Verdana;"> international trade for several essential goods</span><span style="font-family:Verdana;"> in the development of an economy. This study investigated the influence of various factors affecting import trade, and use principal component analysis to determine an empirical model for a comprehensive analysis of the influencing factors of import trade of Rwanda using secondary data </span><span style="font-family:Verdana;">over the period from 1980-2017. The PCA model</span><span style="font-family:Verdana;"> showed that Rwanda’s import trade is principally littered with investment fundamental factors, income consumption factors, price factors, inflation factors, and savings factors and the empirical results showed that Rwanda’s import trade is negatively correlated with the investment fundamental and savings factors, the income consumption factors, price factor, and the inflation are positively correlated and therefore the </span><span style="font-family:Verdana;">forecast for the period 2018-2025 revealed that the import trade of Rwanda may experience an increase. The implication is that unstable price and currency depreciation cause high income consumption and increased import trade volume. The study advises policy makers on international trade first to </span><span style="font-family:Verdana;">pay attention to the accumulation of investment and savings checking if providing support for import trade control and enhance economic security. Second, stabiliz</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;"> the price and manage to keep inflation low and stable. </span><span style="font-family:Verdana;">Third, better </span><span style="font-family:Verdana;">focus on improving domestic production by not permitting Rwandan currency (Frw) to lose the worth, thus directly forming the necessity for foreign merchandise</span><span style="font-family:""> </span><span style="font-family:Verdana;">for investment purposes to increase the level of production exportation, which might have a giant positive impact on saving culture linked to economic growth.展开更多
In Korea construction industry, the increase of tower crane’s usage continuously and the accidents of tower crane are increasing simultaneously. But research on tower crane is insufficient for reducing the tower cran...In Korea construction industry, the increase of tower crane’s usage continuously and the accidents of tower crane are increasing simultaneously. But research on tower crane is insufficient for reducing the tower crane accident. This study aims to derive the importance ranking of accident factors of cab-control tower crane by AHP analysis. AHP survey was conducted on experts such as construction engineer, construction manager, safety engineer, and tower crane operator, who have more than 10-year career. The results of AHP analysis reveal that top ranking factor of cab-control tower crane’s accident is erection work. Therefore, the derived factors should be managed, and the priority measures taken for reducing the tower crane accidents according to the ranking of accident factors.展开更多
Extending the retirement age is an inevitable trend with the extension of the life expectancy of the population, reducing the financial burden of pensions, increasing the utilization rate of human capital, alleviating...Extending the retirement age is an inevitable trend with the extension of the life expectancy of the population, reducing the financial burden of pensions, increasing the utilization rate of human capital, alleviating the shortage of the labor market and other social problems. More and more countries are beginning to impose extended retirement policies, like United States, South Korea, Canada and Nordic countries and so on, all have taken some measures to delay retirement. However, the general social recognition is not high. Both the aged group, the education level and the individual's lifestyle have a significant impact on the delayed retirement age policy. Severe aging situation puts the future pension system at risk, based on the interests of the country, delayed retirement will help utilize the human capital and relieve the country' s financial pressure; from individual perspective, extending retirement age can help reduce the provision for the aged people. This article based on previous literatures review, through conducted the survey of people in Halmstad to analyze the local citizen's perception on delayed retirement and the influencing factors behind. Concluded that willingness of delayed retirement among people is not very high, reasons vary from different kinds of people.展开更多
According to the Law of the People’s Republic of China on the Prevention and Control of Solid Waste Pollution,Basel Convention for the Control of Transboundary Movements of Hazardous Wastes and Their Disposal,Solid W...According to the Law of the People’s Republic of China on the Prevention and Control of Solid Waste Pollution,Basel Convention for the Control of Transboundary Movements of Hazardous Wastes and Their Disposal,Solid Waste Import Management Method and other relevant laws and regulations,the Ministry of Environmental Protection,Ministry of Commerce,National Development and Reform Commission,General Administration of Customs,as well as General Administration of Quality Supervision,Inspection and Quarantine jointly released announcement to make adjustment and revision of the current Prohibited Import Catalogues of Solid Wastes,Restricted Import Catelogues of Solid Waste Used as Raw Material and Non-restricted Import Catelogues of Solid Waste Used as Raw Material,and released Imported Waste Management Catalogues(2017)on August 16th,2017.展开更多
文摘Introduction: Malaria is an important disease, causing high morbidity and mortality, especially in Sub-Saharan Africa. Measuring malaria prevalence using malaria rapid diagnostic tests (mRDTs), particularly among a vulnerable population sub-group, is a vital public health step in discovering effective methods of prevention and control. This study set out to examine the association between “place” and other risk factors with malaria prevalence among Batwa Indigenous People (IP). Methods: An analytical cross-sectional study design was implemented. Two surveys January 2014 (n = 572) and April 2014 (n = 541) involving interviews and testing for malaria using mRDTs were conducted in 10 Batwa settlements where a total of 1113 Batwa of all ages were surveyed and tested. The data were first compiled in MS Excel and then imported and analyzed using STATA ver.14. Descriptive statistics, were generated, followed by bivariable and multivariable regression model analysis to establish associations between the predictor and outcome variables with p ≤ 0.05 considered statistically significant. Results: Overall prevalence was 13.94% (n = 146). There is a significant relationship between settlement (place) and malaria prevalence AOR 11.7, 95% CI (1.38 - 98.93), p-value = 0.02. More males 16.97% (n = 84) tested positive compared to females 11.23% (n = 62) but there was no statistically significant association between gender and mRDT (p-value > 0.005). Children less than 5 years registered high prevalence and there was a significant relationship between age and mRDT (p-value ≤ 0.005). Wealth proxy indicators showed no association with prevalence p-value = 0.390. Season had no association with prevalence (p-value = 0.80). However, the proportion of the day spent in the forest/woodlands was significantly associated with malaria prevalence COR 12.83, 95% CI (1.14 - 143.73) p-value = 0.04. Low elevation was significantly associated with malaria prevalence COR 2.42, 95% CI (1.32 - 4.41), p = 0.004 but sleeping under a net and level of education did not show any association with malaria prevalence. Conclusion: This study highlights the importance of place in predicting malaria prevalence among Batwa Indigenous People a marginalized and remortely located sub-population. This study has shown that place matters in determining malaria prevalence. However, other factors like age, elevation and gender also contribute to malaria prevalence. Batwa have higher prevalence than the national and even non-indigenous populations in the same district. We recommend targeting hotspots intervention approach since it has proven reasonable impact on reducing malaria prevalence.
基金Science and Technology Project of Department of Science and Technology of Yunnan Province(Project No.:202102AY070001-030)The Talent Training Fund of the Joint Logistics Support Force(Project No.:20220105)Science and Technology Project of the 920^(th) Hospital of the Joint Logistics Support Force(Project No.:2020YGD11)。
文摘Objective:To investigate the differences in risk factors and prognosis between young and elderly patients with acute ST-segment elevation myocardial infarction(STEMI)so as to provide a basis for the prevention of young patients with acute STEMI.Methods:Patients initially diagnosed with STEMI in the 920"Hospital of Joint Logistic Support Force of PLA from January 1,2018 to December 31,2022 were retrospectively enrolled in this study.A total of 235 STEMI patients aged≤45 years old and 532 STEMI patients aged≥65 years old were screened.The baseline characteristics,laboratory indicators,clinical characteristics,coronary angiography,SYNTAX score and major adverse cardiovascular events(MACE)during 1-year follow-up were analyzed and compared.Results:A total of 767 STEMI patients were enrolled,including 235 in the young group and 532 in the elderly group.Among the STEM patients in the young group,224 cases were male,and smoking and drinking were common.Compared with the elderly group,the young group had shorter hospital stays and more family history of ischemic heart disease(IHD).The level of low-density lipoprotein in the young group was higher than that in the old group,while the level of high-density lipoprotein in the young group was lower than that in the old group.The level of high uric acid and homocysteine in the young group was significantly higher than that in the old group.The main cause of STEMI in the young group was fatigue,and the most common symptom was angina pectoris.Coronary angiography showed that single vessel disease was more common in the young group than in the elderly group,and the lesion in the young group was the left anterior descending artery.The SYNTAX score was significantly lower in the young group than in the elderly group according to the anatomical characteristics of coronary artery disease.In the forest plot,diabetes mellitus and a family history of IHD showed a trend of major adverse cardiovascular events(MACE)in both groups.Conclusion:Males,smokers,alcohol drinkers and family history of ischemic heart disease are more common in young patients.Common risk factors include fatigue,hyperuricemia,hyperlipidemia and so on.In addition,age itself is an independent risk factor.Management of diabetes,hyperuricemia,and homocysteine levels is essential to reduce the incidence of cardiovascular events in young patients.By controlling these factors,the incidence of young patients with acute STEMI can be effectively prevented and the corresponding prevention and treatment basis can be provided.
文摘In order to investigate the association of fibrin monomer polymerization function (FMPF) with traditional cerebrovascular risk factors and ischemic cerebrovascular disease in old people. 1∶1 paired case-control comparative study was performed for FMPF and traditional cerebrovascular risk factors on 110 cases of old ischemic cerebrovascular disease and 110 controls matched on age, sex and living condition. The results showed that cerebrovascular risk factors were more prevalent in case group than in control group. In the case group, FMPF was significantly higher than in control group. There was a significant positive correlation between hypertension and fibrin monomer polymerization velocity (FMPV), hypertension and fibrinogen (Fbg), alcohol consumption and Fbg, but no significant correlation between diabetic mellitus, smoking and FMPF was found. Among the parameters of blood lipids, there were significant positive correlations between total cholesterol (TC) and parameters of FMPF to varying degrees, triglycerides (TG) and FMPV, TG and Fbg. Our results also showed there were significant linear trends between TC and FMPV (P<0. 001), TC and Fbg (P=0. 0087), TG and FMPV/Amax (maximum absorbance)(P=0. 0143) respectively. Multiple logistic regression analysis revealed that FMPF in case group remained significantly higher than control group after adjustment of all risk factors that were significant in univariate analysis. It was concluded that there is a possible pathophysiological link between FMPF and cerebrovascular risk factors. An elevated FMPF is associated with ischemic cerebrovascular disease and an independent risk factor of this disease. In old people, detection of FMPF might be a useful screening to identify individuals at increased cerebrothrombotic risk.
文摘Aims: to analyze the presence and simultaneity of behavioral risk factors for chronic non-communicable disease (NCD) in adults and the elderly. Methods: quantitative, cross-sectional and observational study. Healthy and unhealthy eating are classified according to the frequency of food consumption. Smoking is expressed by the percentage of smokers. Harmful alcohol consumption by the percentage of individuals who consumed alcoholic beverages at least once in the last 30 days. Classification of the level of physical inactivity required to practice at least 150 minutes of physical activity. Results: the sample constituted 719 people, 535 adults and 184 elderly. The behavioral risk factor reported by most adults 499 (93.3%) and elderly 156 (84.8%) was unhealthy eating. Frequency 72% higher of smoking, four times higher of harmful alcohol consumption and 10% higher of unhealthy food among adults when compared to the elderly. The simultaneity between risk factors was 39% greater in adults than in the elderly. Discussion: risk factors evaluated in this study are key aspects of the development of NCDs. Adults have 2.43 times the chance of presenting two risk factors and 7.73 times the chance of presenting three in relation to the elderly. Conclusion: To achieve more effective and differentiated results, knowing and directing measures to control behavioral risk factors, whether isolated or concurrent, requires specific knowledge.
文摘Objective: To evaluate the association of socio-demographic and clinical characteristics, and risk factors with occurrence of pressure ulcers in institutionalized elderly people. Method: This cross-sectional, analytical study, in quantitative approach, performed from the database analysis linked to the project “Pressure Ulcer in institutionalized elderly people: Association of incidence with the risk factors to functional and nutritional assessment” developed in six long-stay institutions for the elderly people in João Pessoa. Data were analyzed using the Statistical Package for Social Sciences (SPSS) version 20.0. Associations were made through chi square test and Odds Ratio. Results: The clinical conditions of significant associations with the occurrence of pressure ulcers were the variables neurological disorders (p = 0.011) and visual impairment (p = 0.005). As for risk factors, the most important was fecal incontinence (p Conclusion: The analysis of the associations pointed out problems that require intervention in order to prevent health implications of the elderly people and to minimize the risk and occurrence of this injury.
基金supported by the National Natural Science Foundation of China (30600508)the Shanghai Leading Academic Discipline Project (B118)
文摘Objective This study aimed to explore the roles of three common single nucleotide polymorphisms in the X-ray repair cross-complementing group-1 gene (XRCC1) and of life style factors and their possible interactions in the risk of esophageal squamous cell carcinoma (ESCC) in China. Methods A population-based case-control study of 432 cases and 915 controls was conducted in Yangzhong County, Jiangsu Province, China. Subjects were interviewed by trained interviewers using a structured questionnaire that included questions on demographics and life style. XRCC1 genotypes were analyzed using a polymerase chain reaction based restriction fragment length polymorphism (PCR-RFLP) assay. Unconditional logistic regression analysis was used to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for associations of ESCC with XRCCI polymorphisms and lifestyle-related factors. Results Both the drinking of river water and alcohol intake history were significantly associated with an increased risk of ESCC among men with aORs of 4.20 (95% Ch 2.90-6.07) and 2.03 (95% Ch 1.43-2.89), respectively. For women, the corresponding odds ratios were 8.37 (95% CI: 5.09-13.75) for river water drinking and 12.78 (95% CI: 2.69-60.69) for long-term stored rice intake. After the XRCC1 G28152A polymorphism was adjusted for potential confounders, subjects with GA and AA genotypes had an increased risk for ESCC (aOR: 1.21, 95% CI: 0.93-1.56), compared with subjects with a GG genotype, and a positive multiplicative interaction between intake of long-term stored rice and the XRCC1 G28152A polymorphism was observed (P=O.009).Conclusions Our findings suggest that both lifestyle-related factors, including drinking river water, long-term stored rice and alcohol intake, and the XRCC1 G28152A polymorphism were possible risk factors for ESCC, and that the XRCC1 G28152A polymorphism modified the effect of long-term stored rice intake on the risk of ESCC among Chinese people.
基金supported by Social Development of Hainan Province Special Fund of Science and Technology(SF201302)
文摘Objective: To study the relevant risk factors of polycystic ovarian syndrome(PCOS) of Li People so as to provide basis for early diagnosis and treatment of PCOS. Methods: With casecontrol study method, 285 cases of PCOS of Li People were as recruited case group, and 580 cases of non-PCOS of female Li People as control group. Questionnaire was adopted to collect data regarding risk factors of PCOS, then the risk factors of PCOS was searched by univariate and multivariate analysis. Results: Multivariate analysis showed that the risk factors of PCOS included in menstrual cycle disorder(OR=5.824), bad mood(OR=2.852), family history of diabetes(OR=7.008), family history of infertility(OR=11.953), menstrual irregularity of mother(OR=2.557) and lack of physical exercise(OR=1.866). Conclusions: To target the high risk factors of menstrual cycle disorder, family history of diabetes, family history of infertility, family history of diabetes, bad mood and lack of physical exercise of female population, we should implement early screen, diagnose and treatment of POCS in order to reduce the incidence rate of PCOS and improve prognosis of PCOS.
基金supported by the National Key Research and Development Program of China(2016YFC0501203)the National Genetically Modified Organism Project(2016ZX08010005-9)。
文摘Plant mitochondrial phosphate transporters regulate phosphate transport and ATP synthesis. Determining whether they function in abiotic stress response process would shed light on their response to salt stress. We used the CRISPR/Cas9 gene-editing system to mutagenize two mitochondrial phosphate transporters, OsMPT3;1 and OsMPT3;2, to investigate their regulatory roles under salt stress. Two cas9(CRISPR-associated protein9)-free homozygous mutants, mpt33 and mpt30, were confirmed to be stable. Both OsMPT3;1 and OsMPT3;2 were markedly induced by salt stress, and their mutagenesis strongly inhibited growth and development, especially under salt stress. Mutagenesis sharply reduced the accumulation of ATP, phosphate, calcium, soluble sugar, and proline and increased osmotic potential, malondialdehyde, and Na^+ /K^+ ratio under salt stress. Both mutants demonstrate normal growth and development in the presence of ATP, revealing high sensitivity to exogenous ATP under salt stress. The mutants showed lowered rates of Na^+ efflux but also of K^+ and Ca^(2+) influx under salt stress. Mutagenesis of OsMPT3;2 altered the enrichment profiles of differentially expressed genes involved mainly in synthesis of secondary metabolites, metabolism of glycolysis, pyruvate, tricarboxylic acid cycle, in response to salt stress. The mutant displayed significant accumulation differences in 14 metabolites involved in 17 metabolic pathways, and strongly up-regulated the accumulation of glutamine, a precursor in proline synthesis, under salt stress. These findings suggest that the OsMPT3 gene modulates phosphate transport and energy supply for ATP synthesis and triggers changes in accumulation of ions and metabolites participating in osmotic regulation in rice under salt stress, thus increasing rice salt tolerance. This study demonstrates the effective application of CRISPR/Cas9 gene-editing to the investigation of plant functional genes.
基金supported by Liaoning Province Economic and Social Development Research Project (Project No.20221slybkt-007).
文摘This paper examines the impact of key economic factors on trade volumes between China and the Regional Comprehensive Economic Partnership(RCEP)member states.Studies have shown that gross domestic products(GDP),exchange rate,and inflation have an impact on China’s import and export trade volume with RCEP member states.China’s export trade volume to RCEP member states is deeply affected by China’s GDP,but the import trade volume depends on China’s domestic demand and market.The impact of exchange rates on import and export trade volumes varies from country to country.China’s export volume to RCEP member states is generally more affected by the consumption level of its residents than the consumption level of Chinese residents.
文摘Qimin Yaoshu( Important Arts for the People's Welfare) made a detailed record of the diet and its production methods in the middle and lower reaches of the Yellow River during the Wei Dynasty.Hu foods are important parts in the book.Hu foods recorded in Important Arts for the People's Welfare mainly include cheese products,cake products,and dish products.These contents not only reflect the exchange of diet culture between different nationalities in the middle and lower reaches of the Yellow River during this period,but also reflect the breadth and depth of ethnic exchanges and integration in this period.
文摘Diaolou style building is an important residential building of Qiang people. In recent years, Qiang people’s own cultural identities and behavioral awareness have transformed. Due to the lack of attention to the inheritance of original architectural style and the absence of a detailed scientific protection of the landscape, the architectural style of Diaolou style building gradually loses its vitality. It is difficult to control and guide it effectively. And tourism economy which enjoys a direct link with the architecture has been confined to further development. From the perspective of behavioral science, this study innovatively analyzes the Diaolou style building of Qiang people by combining the methodology of Lew in metal of behavior and Analytic Hierarchy Process. Firstly, 32 symbols are chosen as Diaolou architectural style factors from the selection of more than 100 Diaolou architectural decorative symbols. Then by measuring their weight coefficients through the Analytic Hierarchy Process, eight main style factors have been screened out. After field research, we analyze the actual use of the style factors of the six typical villages such as Gina. On this basis, this paper analyzes the behavioral factors of Diaolou style building of Qiang people, deconstructs its use and puts forward a concept which takes style control as a guidance and behavior guidance as a strategy to protect and develop Diaolou style building of Qiang people. It is also proposed that a control and guidance strategy of inheritance and development of Qiang Diaolou architectural style, including master the influencing factors as a whole, follow the principle of people-oriented, compound function, dynamic development and highlighting national aesthetics, based on its style system, and grasp the trend of architectural style, etc. The study provides an effective guarantee for the further development of rural tourism, and a necessary theoretical and technical guidance for the government to adopt targeted steps.
文摘This paper is based on the partnership between China’s higher vocational colleges and industry, and obtains a large number of data on industry-college partnerships through case analysis, interviews and questionnaires. This paper analyzes the main factors that affect industry-college partnerships and the current problems and challenges, then puts forward the solutions.
基金supported by the College of Agriculture,Shiraz University(Grant No.97GRC1M271143)funding from the UK Biotechnology and Biological Sciences Research Council(BBSRC)funded by BBSRC grant award BBS/E/C/000I0330–Soil to Nutrition project 3–Sustainable intensification:optimisation at multiple scales。
文摘This investigation assessed the efficacy of 10 widely used machine learning algorithms(MLA)comprising the least absolute shrinkage and selection operator(LASSO),generalized linear model(GLM),stepwise generalized linear model(SGLM),elastic net(ENET),partial least square(PLS),ridge regression,support vector machine(SVM),classification and regression trees(CART),bagged CART,and random forest(RF)for gully erosion susceptibility mapping(GESM)in Iran.The location of 462 previously existing gully erosion sites were mapped through widespread field investigations,of which 70%(323)and 30%(139)of observations were arbitrarily divided for algorithm calibration and validation.Twelve controlling factors for gully erosion,namely,soil texture,annual mean rainfall,digital elevation model(DEM),drainage density,slope,lithology,topographic wetness index(TWI),distance from rivers,aspect,distance from roads,plan curvature,and profile curvature were ranked in terms of their importance using each MLA.The MLA were compared using a training dataset for gully erosion and statistical measures such as RMSE(root mean square error),MAE(mean absolute error),and R-squared.Based on the comparisons among MLA,the RF algorithm exhibited the minimum RMSE and MAE and the maximum value of R-squared,and was therefore selected as the best model.The variable importance evaluation using the RF model revealed that distance from rivers had the highest significance in influencing the occurrence of gully erosion whereas plan curvature had the least importance.According to the GESM generated using RF,most of the study area is predicted to have a low(53.72%)or moderate(29.65%)susceptibility to gully erosion,whereas only a small area is identified to have a high(12.56%)or very high(4.07%)susceptibility.The outcome generated by RF model is validated using the ROC(Receiver Operating Characteristics)curve approach,which returned an area under the curve(AUC)of 0.985,proving the excellent forecasting ability of the model.The GESM prepared using the RF algorithm can aid decision-makers in targeting remedial actions for minimizing the damage caused by gully erosion.
文摘As the population ages, older people's health and quality of life are becoming a matter of public concern increasingly. Through review of the literatures and analysis of the reasons for falls in older people, we worked out some measures to cope with such a situation, provided the self-care knowledge of falls prevention for older people and improved the quality life of older persons. The recovery process is long, if the old people fall down, which brings a lot of inconvenience to individuals and families, and it can also cause a lot of complications. If wary of fall risk factors, the quality of life of older persons can be improved. According to the different conditions of the elderly, we should take effective measures to create suitable living environment for senior citizens, and propagandize the knowledge of the old people's health care, which has the great significance in preventing the elderly's fall, and improving their living quality.
文摘A developing country like Rwanda heavily </span><span style="font-family:Verdana;">is </span><span style="font-family:Verdana;">keen </span><span style="font-family:Verdana;">on</span><span style="font-family:Verdana;"> international trade for several essential goods</span><span style="font-family:Verdana;"> in the development of an economy. This study investigated the influence of various factors affecting import trade, and use principal component analysis to determine an empirical model for a comprehensive analysis of the influencing factors of import trade of Rwanda using secondary data </span><span style="font-family:Verdana;">over the period from 1980-2017. The PCA model</span><span style="font-family:Verdana;"> showed that Rwanda’s import trade is principally littered with investment fundamental factors, income consumption factors, price factors, inflation factors, and savings factors and the empirical results showed that Rwanda’s import trade is negatively correlated with the investment fundamental and savings factors, the income consumption factors, price factor, and the inflation are positively correlated and therefore the </span><span style="font-family:Verdana;">forecast for the period 2018-2025 revealed that the import trade of Rwanda may experience an increase. The implication is that unstable price and currency depreciation cause high income consumption and increased import trade volume. The study advises policy makers on international trade first to </span><span style="font-family:Verdana;">pay attention to the accumulation of investment and savings checking if providing support for import trade control and enhance economic security. Second, stabiliz</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;"> the price and manage to keep inflation low and stable. </span><span style="font-family:Verdana;">Third, better </span><span style="font-family:Verdana;">focus on improving domestic production by not permitting Rwandan currency (Frw) to lose the worth, thus directly forming the necessity for foreign merchandise</span><span style="font-family:""> </span><span style="font-family:Verdana;">for investment purposes to increase the level of production exportation, which might have a giant positive impact on saving culture linked to economic growth.
文摘In Korea construction industry, the increase of tower crane’s usage continuously and the accidents of tower crane are increasing simultaneously. But research on tower crane is insufficient for reducing the tower crane accident. This study aims to derive the importance ranking of accident factors of cab-control tower crane by AHP analysis. AHP survey was conducted on experts such as construction engineer, construction manager, safety engineer, and tower crane operator, who have more than 10-year career. The results of AHP analysis reveal that top ranking factor of cab-control tower crane’s accident is erection work. Therefore, the derived factors should be managed, and the priority measures taken for reducing the tower crane accidents according to the ranking of accident factors.
文摘Extending the retirement age is an inevitable trend with the extension of the life expectancy of the population, reducing the financial burden of pensions, increasing the utilization rate of human capital, alleviating the shortage of the labor market and other social problems. More and more countries are beginning to impose extended retirement policies, like United States, South Korea, Canada and Nordic countries and so on, all have taken some measures to delay retirement. However, the general social recognition is not high. Both the aged group, the education level and the individual's lifestyle have a significant impact on the delayed retirement age policy. Severe aging situation puts the future pension system at risk, based on the interests of the country, delayed retirement will help utilize the human capital and relieve the country' s financial pressure; from individual perspective, extending retirement age can help reduce the provision for the aged people. This article based on previous literatures review, through conducted the survey of people in Halmstad to analyze the local citizen's perception on delayed retirement and the influencing factors behind. Concluded that willingness of delayed retirement among people is not very high, reasons vary from different kinds of people.
文摘According to the Law of the People’s Republic of China on the Prevention and Control of Solid Waste Pollution,Basel Convention for the Control of Transboundary Movements of Hazardous Wastes and Their Disposal,Solid Waste Import Management Method and other relevant laws and regulations,the Ministry of Environmental Protection,Ministry of Commerce,National Development and Reform Commission,General Administration of Customs,as well as General Administration of Quality Supervision,Inspection and Quarantine jointly released announcement to make adjustment and revision of the current Prohibited Import Catalogues of Solid Wastes,Restricted Import Catelogues of Solid Waste Used as Raw Material and Non-restricted Import Catelogues of Solid Waste Used as Raw Material,and released Imported Waste Management Catalogues(2017)on August 16th,2017.