During the laser foil interaction, the output ion beam quality including the energy spread and beam divergence can be improved by the target ablation, due to the direct laser acceleration (DLA) electrons generated i...During the laser foil interaction, the output ion beam quality including the energy spread and beam divergence can be improved by the target ablation, due to the direct laser acceleration (DLA) electrons generated in tile ablation plasma. The acceleration field established at the target rear by these electrons, which is highly directional and triangle-envelope, is helpful for the beam quality. With the help of the target ablation, both the beam divergence and energy spread will be reduced. If the ablation is more sufficient, the impact of DLA-electron-caused field will be strengthened, and the beam quality will be better, confirmed by the particle-in-cell simulation.展开更多
Due to its lower risk of consequences when compared to a radical approach, focal treatment is a viable and minimally invasive option for treating specific localized prostate cancer. Although several recent good nonran...Due to its lower risk of consequences when compared to a radical approach, focal treatment is a viable and minimally invasive option for treating specific localized prostate cancer. Although several recent good nonrandomized trials have suggested that focused therapy may be an alternative choice for some patients, additional high-quality evidence is needed before it can be made widely available as a conventional treatment. As a result, we have summarized the most recent findings from the 38th Annual European Association of Urology Congress, one of the most renowned annual conferences in the area of urology, regarding focal ablation therapy for patients with localized prostate cancer. Additionally, we also provided clinical trials in progress for researchers to better understand the current research status of this field.展开更多
We investigate the angular distribution and average kinetic energy of ions produced during ultrafast laser ablation (ULA) of a copper target in high vacuum. Laser produced plasma (LPP) is induced by irradiating th...We investigate the angular distribution and average kinetic energy of ions produced during ultrafast laser ablation (ULA) of a copper target in high vacuum. Laser produced plasma (LPP) is induced by irradiating the target with Ti:Sapphire laser pulses of -50 fs and 800 nm at an angle of incidence of 45°. An ion probe is moved along a circular path around the ablation spot, thereby allowing characterization of the time-of-flight (TOF) of ions at different angles relative to the normal target. The angular distribution of the ion flux is well-described by an adiabatic and isentropic expansion model of a plume produced by solid-target laser ablation (LA). The angular width of the ion flux becomes narrower with increasing laser fluence. Moreover, the ion average kinetic energy is forward-peaked and shows a stronger dependence on the laser pulse fluence than on the ion flux. Such results can be ascribed to space charge effects that occur during the early stages of LPP formation.展开更多
基金Supported by the National Basic Research Program of China under Grant No 2013CBA01502the National Natural Science Foundation of China under Grant Nos 11025523 and J1103206the National Major Scientific Instruments and Equipment Development Projects under Grant No 2012YQ030142
文摘During the laser foil interaction, the output ion beam quality including the energy spread and beam divergence can be improved by the target ablation, due to the direct laser acceleration (DLA) electrons generated in tile ablation plasma. The acceleration field established at the target rear by these electrons, which is highly directional and triangle-envelope, is helpful for the beam quality. With the help of the target ablation, both the beam divergence and energy spread will be reduced. If the ablation is more sufficient, the impact of DLA-electron-caused field will be strengthened, and the beam quality will be better, confirmed by the particle-in-cell simulation.
基金supported by the Luzhou City Science and Technology Bureau (No.2020LZXNYDJ10 and 2020LZXNYDJ14)Cooperation Project between the Second People’s Hospital of Deyang and Southwest Medical University (No.2022DYEXNYD002)。
文摘Due to its lower risk of consequences when compared to a radical approach, focal treatment is a viable and minimally invasive option for treating specific localized prostate cancer. Although several recent good nonrandomized trials have suggested that focused therapy may be an alternative choice for some patients, additional high-quality evidence is needed before it can be made widely available as a conventional treatment. As a result, we have summarized the most recent findings from the 38th Annual European Association of Urology Congress, one of the most renowned annual conferences in the area of urology, regarding focal ablation therapy for patients with localized prostate cancer. Additionally, we also provided clinical trials in progress for researchers to better understand the current research status of this field.
基金supported by the China National Scholarship Fund,the Executive Programme Italy-China for the years 2010–2012(No.CN10M02)the National Natural Science Foundation of China(No.11104201)+1 种基金the Key Laboratory of Opto-electronic Information Technology,Ministry of Education(Tianjin University)Open Fundthe European Union Seventh Framework Programme(FP7/2007–2013)(No.264098-MAMA)
文摘We investigate the angular distribution and average kinetic energy of ions produced during ultrafast laser ablation (ULA) of a copper target in high vacuum. Laser produced plasma (LPP) is induced by irradiating the target with Ti:Sapphire laser pulses of -50 fs and 800 nm at an angle of incidence of 45°. An ion probe is moved along a circular path around the ablation spot, thereby allowing characterization of the time-of-flight (TOF) of ions at different angles relative to the normal target. The angular distribution of the ion flux is well-described by an adiabatic and isentropic expansion model of a plume produced by solid-target laser ablation (LA). The angular width of the ion flux becomes narrower with increasing laser fluence. Moreover, the ion average kinetic energy is forward-peaked and shows a stronger dependence on the laser pulse fluence than on the ion flux. Such results can be ascribed to space charge effects that occur during the early stages of LPP formation.