The current Grover quantum searching algorithm cannot identify the difference in importance of the search targets when it is applied to an unsorted quantum database, and the probability for each search target is equal...The current Grover quantum searching algorithm cannot identify the difference in importance of the search targets when it is applied to an unsorted quantum database, and the probability for each search target is equal. To solve this problem, a Grover searching algorithm based on weighted targets is proposed. First, each target is endowed a weight coefficient according to its importance. Applying these different weight coefficients, the targets are represented as quantum superposition states. Second, the novel Grover searching algorithm based on the quantum superposition of the weighted targets is constructed. Using this algorithm, the probability of getting each target can be approximated to the corresponding weight coefficient, which shows the flexibility of this algorithm. Finally, the validity of the algorithm is proved by a simple searching example.展开更多
This paper presents a method for detecting the small infrared target under complex background. An algorithm, named local mutation weighted information entropy （LMWIE）, is proposed to suppress background. Then, the g...This paper presents a method for detecting the small infrared target under complex background. An algorithm, named local mutation weighted information entropy （LMWIE）, is proposed to suppress background. Then, the grey value of targets is enhanced by calculating the local energy. Image segmentation based on the adaptive threshold is used to solve the problems that the grey value of noise is enhanced with the grey value improvement of targets. Experimental results show that compared with the adaptive Butterworth high-pass filter method, the proposed algorithm is more effective and faster for the infrared small target detection.展开更多
Although it is reported that the targeting ability of hyaluronic acid(HA)-based nanoparticles(NPs) is molecular weight(MW) dependent,the influence of HA MW on targeting efficiency of HA-functionalized NPs and the unde...Although it is reported that the targeting ability of hyaluronic acid(HA)-based nanoparticles(NPs) is molecular weight(MW) dependent,the influence of HA MW on targeting efficiency of HA-functionalized NPs and the underlying mechanism remain elusive. In this study,we constituted three HA-functionalized Dox-loaded NPs(Dox/HCVs) different HA MWs(7,63,and 102 k Da) and attempted to illustrate the effects of HA MW on the targeting efficiency.The three Dox/HCVs had similar physiochemical and pharmaceutical characteristics,but showed different affinity to CD44 receptor. Furthermore,Dox/HCV-63 exerted the best targeting effect and the highest cytotoxicity compared with Dox/HCV-7 and Dox/HCV-102. It was interesting to found that both the HA-CD44 binding affinity and induced CD44 clustering by HA-based NPs were HA MW-dependent,the two of which determine the apparent targeting efficacy of Dox/HCV NPs in the conflicting directions. Those results laid a good foundation for rationally designing HA-based NPs in cancer therapy.展开更多
To avoid or reduce the influence of unpredictable motion mode on data association, a new computing method of weighted coefficients of measurements for PDAF is presented in which it is assumed that the current turn rat...To avoid or reduce the influence of unpredictable motion mode on data association, a new computing method of weighted coefficients of measurements for PDAF is presented in which it is assumed that the current turn rate of a maneuvering target changes within a limited range and its turn may be in arbitrary direction during data association. Thus, the predicted center for computing the weighted coefficients is a curved surface in 3-D space, which differs from the predicted center for setting up a validation gate, namely, a point in 3-D space. The distance between a measurement and the curved surface is used to compute its weighted coefficient. To reduce the computational complexity of weighted coefficients, the formulas for computing the maneuvering direction angle and turn rate corresponding to a measurement are presented. Simulation results show the proposed method reduces the percentage of lost tracks and improves the state estimation accuracy in tracking a maneuvering target using PDAF in the presence of clutter.展开更多
提出一种基于融合主客观信息组合赋权逼近理想解(Technique for Order Preference by Similarity to an Ideal Solution,TOPSIS)的海上目标威胁评估模型。从目标的作战能力、活动情况和其他影响因素构建海上目标威胁评估指标体系;在层...提出一种基于融合主客观信息组合赋权逼近理想解(Technique for Order Preference by Similarity to an Ideal Solution,TOPSIS)的海上目标威胁评估模型。从目标的作战能力、活动情况和其他影响因素构建海上目标威胁评估指标体系;在层次分析法(Analytical Hierarchy Process,AHP)和熵权法的基础上运用线性加权组合法确定主客观综合指标权重;利用TOPSIS法计算各目标的正负理想解相对贴近度,获得目标的威胁度排序。通过仿真实例证明了所提海上目标威胁评估方法的有效性。展开更多
基金the National Natural Science Foundation of China (60773065).
文摘The current Grover quantum searching algorithm cannot identify the difference in importance of the search targets when it is applied to an unsorted quantum database, and the probability for each search target is equal. To solve this problem, a Grover searching algorithm based on weighted targets is proposed. First, each target is endowed a weight coefficient according to its importance. Applying these different weight coefficients, the targets are represented as quantum superposition states. Second, the novel Grover searching algorithm based on the quantum superposition of the weighted targets is constructed. Using this algorithm, the probability of getting each target can be approximated to the corresponding weight coefficient, which shows the flexibility of this algorithm. Finally, the validity of the algorithm is proved by a simple searching example.
基金supported by the National Natural Science Foundation of China (61171194)
文摘This paper presents a method for detecting the small infrared target under complex background. An algorithm, named local mutation weighted information entropy （LMWIE）, is proposed to suppress background. Then, the grey value of targets is enhanced by calculating the local energy. Image segmentation based on the adaptive threshold is used to solve the problems that the grey value of noise is enhanced with the grey value improvement of targets. Experimental results show that compared with the adaptive Butterworth high-pass filter method, the proposed algorithm is more effective and faster for the infrared small target detection.
基金supported by the National Basic Research Program of China (No. 81573371)the key projects of Liaoning Province Department of Education (No. 2017LZD03)
文摘Although it is reported that the targeting ability of hyaluronic acid(HA)-based nanoparticles(NPs) is molecular weight(MW) dependent,the influence of HA MW on targeting efficiency of HA-functionalized NPs and the underlying mechanism remain elusive. In this study,we constituted three HA-functionalized Dox-loaded NPs(Dox/HCVs) different HA MWs(7,63,and 102 k Da) and attempted to illustrate the effects of HA MW on the targeting efficiency.The three Dox/HCVs had similar physiochemical and pharmaceutical characteristics,but showed different affinity to CD44 receptor. Furthermore,Dox/HCV-63 exerted the best targeting effect and the highest cytotoxicity compared with Dox/HCV-7 and Dox/HCV-102. It was interesting to found that both the HA-CD44 binding affinity and induced CD44 clustering by HA-based NPs were HA MW-dependent,the two of which determine the apparent targeting efficacy of Dox/HCV NPs in the conflicting directions. Those results laid a good foundation for rationally designing HA-based NPs in cancer therapy.
文摘To avoid or reduce the influence of unpredictable motion mode on data association, a new computing method of weighted coefficients of measurements for PDAF is presented in which it is assumed that the current turn rate of a maneuvering target changes within a limited range and its turn may be in arbitrary direction during data association. Thus, the predicted center for computing the weighted coefficients is a curved surface in 3-D space, which differs from the predicted center for setting up a validation gate, namely, a point in 3-D space. The distance between a measurement and the curved surface is used to compute its weighted coefficient. To reduce the computational complexity of weighted coefficients, the formulas for computing the maneuvering direction angle and turn rate corresponding to a measurement are presented. Simulation results show the proposed method reduces the percentage of lost tracks and improves the state estimation accuracy in tracking a maneuvering target using PDAF in the presence of clutter.
文摘提出一种基于融合主客观信息组合赋权逼近理想解(Technique for Order Preference by Similarity to an Ideal Solution,TOPSIS)的海上目标威胁评估模型。从目标的作战能力、活动情况和其他影响因素构建海上目标威胁评估指标体系;在层次分析法(Analytical Hierarchy Process,AHP)和熵权法的基础上运用线性加权组合法确定主客观综合指标权重;利用TOPSIS法计算各目标的正负理想解相对贴近度,获得目标的威胁度排序。通过仿真实例证明了所提海上目标威胁评估方法的有效性。
