Strategies for Fostering Interaction in Online Classrooms:A Conversation Analysis of Teacher-Student Verbal Interaction in Random Questioning in Pandemic-Initiated Online Teaching

This paper aims to explore how a veteran teacher organizes online teaching initiated by the pandemic and how she deals with the problems in online teacher-student verbal interaction.By analyzing a corpus of 20 audio-recorded online lessons between a math teacher and her students during the COVID-19 pandemic from April 11 to May 10,2022,four interactional segments are selected as the focus of the study.The results of the conversation analysis of the segments showed that students’modesty,lack of confidence,lack of ability,and network delay are the main factors affecting online teacher-student interaction.By encouraging students to answer questions,enlightening students to give answers,enriching students’answers,and entertaining the teaching atmosphere(“4Es”strategies),the teacher solved the problems successfully.The findings from this study can provide pedagogical experience and implications for practical teaching.

A Case Study of Computer-based Teacher-Student Interaction outside Class

This case study examines the interaction through emails between a professor and one of his third-year students outside of the classroom to explore the problems in the teacher-student interaction.It shows that confronted with difficulties,the student turns directly to her teacher,yet failing to make her specific difficulties known,and the teacher spares no pains to exemplify the doing of assignments,yet knowing little about his student’s knowings and unknowings.At the end of the article are some enlightenments:seeking help after self-attempting and helping after knowing.

脓毒症诊治中Ang/Tie信号通路的研究进展

脓毒症以及伴随的多器官功能障碍是一组常见的临床综合征,其患病率随着人口老龄化逐年上升。全球每年发生2000万例脓毒症,死亡率为26%。早期准确诊断脓毒症,有利于及时采取针对性的治疗策略,这是降低病死率的关键。内皮细胞是外源病原体或内源性损伤信号的早期作用对象。研究提示,内皮细胞的结构改变与功能活化在脓毒症的发生、发展中发挥重要作用。作为内皮细胞专属信号通路,血管生成素(angiopoietin,Ang)/酪氨酸激酶受体(tyrosine kinase receptor,Tie)在内皮细胞的异常激活和损伤中发挥重要作用。Ang/Tie信号通路主要包括2种位于内皮细胞中的酪氨酸激酶受体(Tie1、Tie2)和4种分泌性糖蛋白配体(Ang-1、Ang-2、Ang-3、Ang-4)。机制研究方面,Ang-1可持续性激活Tie2受体,维持细胞与细胞、细胞与基质间的相互作用,支持血管内皮细胞正常的生理功能;Ang-2是Ang-1拮抗剂,可竞争性阻断Ang-1与Tie2受体结合。脓毒症环境下,Ang-1下降,Ang-2升高,Ang-1/Ang-2的比值下降。Ang-2竞争性阻断Ang-1与可溶性Tie2受体结合,内皮细胞处于严重异常激活状态。Ang-2介导肝素酶的释放导致糖萼损伤,可引起血管通透性增加;Ang-2可促进炎症反应;Ang/Tie信号系统失调介导凝血功能障碍,Ang-2升高是弥散性血管内凝血的前哨性事件。临床病情监测方面,Ang-2>5.61 ng/mL,诊断脓毒症的灵敏度为74.36%;Ang-2持续升高,提示内皮功能难以恢复,器官发生功能性改变。早期动态监测Ang-2可用于预测脓毒症相关肺损伤、急性肾损伤。Ang-2/Ang-1比值上升、Ang1/可溶性Tie2比值下降可预测脓毒症患者90 d病死率(ROC曲线面积分别为0.787和0.704)。Ang-2和可溶性Tie-2水平下降,则提示脓毒症血浆置换有效。靶向Ang/Tie信号通路的动物实验获得一定成功,但目前临床试验未能获得有价值的结果。脓毒症相关Ang/Tie信号通路有待于进一步深入研究。

益母草注射液通过其生物碱成分上调Tie-2、VEGFR2和VEGF促进斑马鱼血管新生

目的:研究益母草注射液在斑马鱼血管损伤模型中的促血管生成作用,并阐明潜在的物质基础和分子机制。方法:采用HPLC-PAD和TLC技术检测益母草注射液的主要成分;利用舒尼替尼诱导转基因Tg(flk1:eGFP)斑马鱼血管损伤模型,益母草注射液干预治疗后,测量斑马鱼节间血管(ISVs)长度,QT-PCR检测血管生成相关基因的表达水平。结果:发现益母草注射液的主要成分是水苏碱、胆碱和葫芦巴碱;其中,益母草注射液、葫芦巴碱和胆碱可减轻化学诱导的斑马鱼血管损伤,其作用机制涉及益母草注射液上调Tie-2、VEGF和VEGFR2的表达,其主要成分葫芦巴碱上调Tie-2和VEGF的表达,胆碱上调VEGF和VEGFR2的表达。结论:益母草注射液及其主要生物碱成分可通过上调Tie-2、VEGFR2和VEGF来促进血管生成。

Optimizing Teacher-Student Collaborative Assessment in the Production-Oriented Approach:A Dialectical Research

Teacher-student collaborative assessment(TSCA)aims to address the challenges of responding to students’work in the Production-Oriented Approach:low efficiency and poor effectiveness.As part of a bigger project carried out in a Chinese university over a period of three years,the present study explored how the teacher prepared and implemented TSCA in class,especially with a focus on how she determined the assessing objective and worked collaboratively with her students in class to achieve it,using the students’written and translated texts as examples.By adopting the dialectical research(DR)method,this paper collected qualitative data such as teaching plans,classroom recordings,and reflective journals of the teacher-researcher(the author),along with students’written drafts and translated texts.TSCA theory and classroom practice have been refined simultaneously by means of putting theory into practice and reflecting upon it.The optimized pre-class and in-class procedures may shed some light on applying TSCA to L2 classrooms.

基于Bow-Tie-LOPA的煤矿安全风险评估方法应用研究

为解决传统安全评估方法的局限性,有效降低煤矿安全事故、提升煤矿安全管理效能,提出基于Bow-Tie模型的LOPA煤矿安全风险评估方法,通过研究两种方法的概念并分析两种方法相结合的应用,综合应用Bow-Tie-LOPA方法进行煤矿安全风险评估,分析验证Bow-Tie-LOPA方法在煤矿安全风险评估中的可行性和有效性;利用Bow-Tie模型绘制煤矿安全风险事件因果链,找出可供LOPA方法分析的事故场景,并基于LOPA分析风险事件发生率和后果,利用风险矩阵和确定风险等级的方法,进一步评估事故场景,以确定煤矿安全风险后果以及安全保护措施。研究结果表明:LOPA方法的引入有利于Bow-Tie模型分析煤矿复杂事故和危机情境,提高煤矿安全风险管理水平。

调控Ang/Tie信号通路治疗眼底新生血管性疾病的研究进展

抗血管内皮生长因子(VEGF)治疗应用于眼底新生血管疾病领域以来,在提高视力、稳定疾病病变和在某些情况下逆转疾病方面显示了卓越的效果。但抗VEGF治疗需要频繁玻璃体内注射给药,患者治疗负担重,长期疗效受影响。前期临床研究发现,调控血管生成素(Ang)/含免疫球蛋白样环和上皮生长因子样域酪氨酸激酶(Tie)通路在眼底新生血管疾病的治疗中有较好的效果。目前已发布了3个Ang/Tie通路阻断药物治疗眼底新生血管疾病的临床研究数据,其中靶向VEGF-A和Ang-2的双特异性免疫球蛋白G1抗体faricimab进入了Ⅲ期临床试验并达到终点,faricimab的2种延长治疗间隔(12周和16周)的给药方案均被证实有效。本文基于已发表的研究报告,就调控Ang/Tie通路在眼底新生血管性疾病治疗中的作用及临床应用作一综述,总结分析Ang/Tie通路的作用机制以及未来药物的应用前景。

On the Effect of Teacher Talk on Teacher-Student Rapport in College English Classroom

This paper aimed to investigate the effect of teacher talk on teacher-student rapport in college English classroom.Be sides,it attempted to analyze how to build teacher-student rapport in English classroom based on the theories of teacher Talk,hoping that it can assist teachers to upgrade their awareness in teacher talk and increase language learning and teaching efficiency.

Changes in Argumentation Performance:Effects of Teacher-Student Collaborative Assessment

This paper compares the effectiveness of one-semester-long instruction of teacher-student collaborative assessment(TSCA)and trained peer review assessment(TPRA).Dependent variables include occurrence of structural elements of the simplified Toulmin model,and improvement of argumentation substance which refers to the quality of reasoning reflected in Toulmin structural elements.Eighty-one sophomore English majors from TSCA group(n=41)and TPRA group(n=40)were asked to construct two argumentative essays at both the beginning and the end of the semester.The results reveal that the TSCA group produced significantly more counterargument claims and rebuttal data.Additionally,the TSCA group significantly outperformed TPRA group in constructing stronger counterargument claim,rebuttal claim and rebuttal data.

A Qualitative Study on Teacher-student Collaborative Assessment in College Students’ Oral English

This article examines the application of Teacher-student Collaborative Assessment in college students’oral English.Qualitative Study data were collected during 16 weeks teaching practice and included the students’and the examiner’s interviews.The result indicates that most students’oral English has been improved.They prefer this assessment model,and their English learning interest and proficiency has been enhanced as well.

酸性成纤维细胞生长因子调控Ang1/Tie2信号通路抑制炎症促进血管内皮细胞功能恢复

目的:探讨酸性成纤维细胞生长因子(aFGF)对人脐静脉内皮细胞(HUVEC)功能的影响,以及Ang1/Tie2通路在其中的作用。方法:培养HUVEC细胞,不同浓度脂多糖(LPS)和aFGF刺激HUVEC,CCK-8实验确定刺激浓度,并观察生长活性;细胞划痕实验检测aFGF对HUVEC迁移能力的影响;Westernblot实验检测增殖蛋白PCNA,凋亡蛋白Cleavedcaspase3、Bax,抗凋亡蛋白Bcl2,炎症相关蛋白NLRP3、IL-1β、IL-6、TNF-α、IL-4和IL-10,血管生成相关蛋白CD31和通路相关蛋白Ang1、Tie2的表达水平;免疫荧光实验检测PCNA、Cleavedcaspase3、IL-6、IL-10以及CD31的荧光强度。分离小鼠主动脉,离体培养后进行免疫荧光实验,观察PCNA、Cleavedcaspase3、IL-6、IL-10以及CD31蛋白的荧光强度。结果:CCK-8实验显示LPS抑制HUVEC生长活性,5μg/mL为最适刺激浓度(P<0.01);aFGF促进HUVEC生长活性,其中100ng/mL为最适刺激浓度(P<0.01)。细胞划痕实验提示aFGF促进细胞迁移。Westernblot和免疫荧光实验结果显示,aFGF促进增殖蛋白和血管功能蛋白表达,抑制凋亡蛋白和炎症蛋白表达,上调Ang1/Tie2通路蛋白(P<0.05)。离体血管免疫荧光实验显示aFGF上调PCNA、IL-10以及CD31的荧光强度,下调Cleavedcaspase3和IL-6的荧光强度(P<0.05)。结论:aFGF增强HUVEC生长活性和迁移能力,促进其增殖,抑制其凋亡,并通过调控Ang1/Tie2通路抑制炎症反应,促进血管功能修复。

浅谈TIE-固定篦床的优化升级

TIE-固定篦床采用中心分区供风、微调风阀、水滴型高效篦板等技术,用水平出风的高速气流快速急冷熟料,不仅系统可获得温度较高且稳定的二次风,还能均布熟料,减少粗细熟料的离析分布,从源头上控制“红河”的产生;在稳定较高的二次风温下,还可将料层厚度总体降低至650mm左右,大幅减小后续所有冷却风机的总体负载阻力,进一步有利于熟料的冷却和降低冷却电耗。实践表明,使用TIE-固定篦床局部替换旧的固定篦床,能有效地提高二次风温,降低烧成系统的能耗,还可显著提高熟料的质量。

An Action Research Report on Teacher-Student Interaction in EFL Class

This essay is an action research report, focusing on the analysis of a common problem in EFL teaching---passive class. By analyzing the data collected in an EFL class, the author testifies the hypotheses, reflects on some possible reasons for the passive class and proposes suggestions to improve the teacher-student interaction.

An Analysis on Teacher-student Role Changing in Interactive Teaching Mode

Teachers and students play important roles in teaching activity,and they are the most essential parts of the system.The relationship between teachers and students,the core schooling interpersonal relationship,directly determines whether the teach ing activities can go smoothly or not,and is an important index to measure the quality of teachers and students'school life,and also is an important factor that affects the social function of education.For a long time,relationship between teachers and students has been a hot topic in education and in different sectors of the society.This dissertation aims at discussing the teacher-student role changing in interactive teaching mode to provide reference for building a harmonious relationship between teachers and stu dents.

The Influence of Parent-Child Relationship on Pupils’ Learning Motivation: The Mediating Role of Teacher-Student Relationship

Objective:The study is to analyze the influence of parent-child relationship on pupils’learning motivation,and to explore the mediating mechanism of teacher-student relationship in parent-child relationship and learning motivation.Method:This study conducted a questionnaire survey on 213 pupils in Grades 5 and 6 in two schools in Beijing using Pianta’s teacher-student relationship scale revised by Qu,Dornbush’s parent-child intimacy scale revised by Zhang and the learning motivation scale adapted by Hu.Results:Gender,grade,whether they are the only child and to be a class cadre or not show significant differences in some dimensions of parent-child relationship,teacher-student relationship and learning motivation.The total scores of parent-child relationship,teacher-student relationship and learning motivation are positively correlated,and some sub dimensions are also significantly correlated.Parent-child relationship and teacher-student relationship have a significant positive predictive effect on learning motivation,and parent-child relationship has a significant positive predictive effect on teacher-student relationship.Teacher-student relationship plays a mediating role in the influence of parent-child relationship on learning motivation.Conclusions:Parent-child relationship can promote the relationship between teachers and students,and then enhance pupils’learning motivation.

Research on the Application of Intelligent Evaluation and Teacher-student Cooperation Assessment System in Teaching English Writing

Low efficiency in teaching and time-consuming in writing evaluation are two big problems for college English teachers.Therefore,it is necessary to create a new teaching model to solve these problems existing in traditional classroom-based teaching.This research adopts the research methods of test comparison before and after the students’composition experiment,questionnaire and semi-open interviews.Empirical research on a new teaching model that integrates the intelligent composition review and reform system represented by Piangai.com and the collaborative evaluation of teachers and students is conducted.The research results show that the new writing teaching model improves the quality of students’writing,promotes students’learning initiative,and enhances students’writing self-efficacy.This writing teaching model provides ideas for solving the problem of time-consuming and inefficient English writing teaching in large classes.

Influence of network structure on spreading dynamics via tie range

There are various phenomena of malicious information spreading in the real society, which cause many negative impacts on the society. In order to better control the spreading, it is crucial to reveal the influence of network structure on network spreading. Motifs, as fundamental structures within a network, play a significant role in spreading. Therefore, it is of interest to investigate the influence of the structural characteristics of basic network motifs on spreading dynamics.Considering the edges of the basic network motifs in an undirected network correspond to different tie ranges, two edge removal strategies are proposed, short ties priority removal strategy and long ties priority removal strategy. The tie range represents the second shortest path length between two connected nodes. The study focuses on analyzing how the proposed strategies impact network spreading and network structure, as well as examining the influence of network structure on network spreading. Our findings indicate that the long ties priority removal strategy is most effective in controlling network spreading, especially in terms of spread range and spread velocity. In terms of network structure, the clustering coefficient and the diameter of network also have an effect on the network spreading, and the triangular structure as an important motif structure effectively inhibits the spreading.

Seismic effectiveness evaluation and optimized design of tie up method for securing museum collections

To quantify the seismic effectiveness of the most commonly used fishing line tie up method for securing museum collections and optimize fixed strategies for exhibitions,shaking table tests of the seismic systems used for typical museum collection replicas have been carried out.The influence of body shape and fixed measure parameters on the seismic responses of replicas and the interaction behavior between replicas and fixed measures have been explored.Based on the results,seismic effectiveness evaluation indexes of the tie up method are proposed.Reasonable suggestions for fixed strategies are given,which provide a basis for the exhibition of delicate museum collections considering the principle of minimizing seismic responses and intervention.The analysis results show that a larger ratio of height of mass center to bottom diameter led to more intense rocking responses.Increasing the initial pretension of fishing lines was conducive to reducing the seismic responses and stress variation of the lines.Through comprehensive consideration of the interaction forces and effective securement,it is recommended to apply 20%of breaking stress as the initial pretension.For specific museum collections that cannot be effectively protected by the independent tie up method,an optimized strategy of a combination of fishing lines and fasteners is recommended.

基于Ansys/Bow-Tie燃气泄漏的双向风险分析

燃气泄漏事故伴随着爆炸、中毒等多项风险威胁,造成经济损失和伤亡损失。利用Ansys/Bow-Tie建立扩散模型与分析计算模型,将燃气泄漏定性与定量分析。研究表明:在定性变化中,燃气泄漏后泄漏区域的燃气扩散速度呈指数大模块式上升,扩散速度极快;在定量变化中,燃气泄漏的主要风险来源于巡检不足以及检维修不及时可能发生的概率最大,分别为0.039和0.046,通过加装有毒有害气体仪表报警监测群和对大风险问题加强监控可为风险管控提供帮助。

基于STPA和Bow-Tie模型的地面无人平台系统安全分析方法

随着地面无人平台(Unmanned Ground Vehicles,UGVs)在复杂作业环境中的潜在应用和战略价值日益凸显,确保其自主行为的安全性变得至关重要。提出一种结合系统理论过程分析(System-Theoretic Process Analysis,STPA)和Bow-Tie模型的地面无人平台系统安全分析方法。围绕遥控操作地面无人平台系统安全,通过STPA方法识别UGV系统中的不安全控制行为及其潜在风险,并利用Bow-Tie模型分析从损失致因场景到可能事故后果的事件链,得到风险传播路径和风险扩散路径。最终,基于Bow-Tie分析结果确定主被动安全分级控制措施,并通过自主安全控制器实现了系统安全管理。