Modern technology-based exploration of mechanism of traditional Chinese medicine in prevention and treatment of gastric cancer

This review comments on the article“To explore the mechanism of Yigong San anti-gastric cancer and immune regulation”.We are interested that the article applied network pharmacology and bioinformatics techniques to elucidate the mechanism of action of Yigong Sang,a traditional Chinese medicine(TCM),in the treatment of gastric cancer(GC).The mechanism of action of Yigong Sang in the treatment of GC has not yet been elucidated because it is composed of multiple Chinese medicines with multiple components and multiple targets.The emergence of network pharmacology and bioinformatics analysis helps explain the mechanism of action of TCM in preventing and treating GC,and provides a possibility for TCM to transform from empirical to evidence-based medicine.This is of great significance for the application of TCM in oncology,new drug development,formula optimization,and the improvement of clinical efficacy.

Study on Driving Technology Innovation Using Patent Management Mechanism

In order to improve the cigarette enterprise technology innovation and patent management status, the macro work should start from the four aspects of patent ideology introduction, patent organization design, perfecting patent system and implementation of specific measures, and attention should be attached to strengthen the cooperation of the cigarette enterprise management departments. On the other hand, Jn the microscopic work level, it should build the culture atmosphere of the entire tobacco industry respect intellectual property rights, actively cultivate the na- tional patent agents and patent engineers, and gradually promote the patent work to develop in the direction of specialization, self-independence, so as to construct a scientific mechanism for patent management, and enhance the core competitiveness of the tobacco industry.

Teaching Experiment in Engineering Mechanics Based on Simulation Technology:A Case Study

This paper explores the integration of simulation technology in Engineering Mechanics(EM)teaching in vocational colleges.A case study was conducted using the tensile test as an example,and digital resources,such as colored Mises stress nephograms,were obtained.These resources were integrated into the original curriculum to conduct teaching experiments.The results show that the use of digital resources significantly improved the quality of teaching in EM.The integration of simulation technology in EM teaching provides a promising direction for the improvement of vocational education and the cultivation of high-quality skilled talents.The development and application of more simulation-based teaching cases should be studied by scholars.

Application Strategies of BIM Technology in Highway Electromechanical Engineering

The transportation system is vital for social and economic development.With the rapid economic development,the demand for highways has been increasing.Mechanical and electrical engineering is a crucial part of highway construction,affecting the expressway’s later use.Applying building information modeling(BIM)technology in highway electromechanical engineering allows for the visibility and simulation of mechanical and electrical engineering construction,providing scientific guidance for construction.In this research,the author analyzes the advantages of BIM technology in highway electromechanical engineering and the basic composition of electromechanical engineering.The research proposes strategies and cases for applying BIM technology in highway electromechanical engineering.The ultimate goal of this research is to improve the construction of highways in terms of electromechanical engineering.

Mechanism and monitoring and early warning technology for rockburst in coal mines

On the basis of the massive amount of published literature and the long-term practice of our research group in the field of prevention and control of rockburst,the research progress and shortcomings in understanding the rockburst phenomenon have been comprehensively in-vestigated.This study focuses on the occurrence mechanism and monitoring and early warning technology for rockburst in coal mines.Results showed that the prevention and control of rockburst had made significant progress.However,with the increasing mining depth,several unre-solved concerns remain challenging.From the in-depth research and analysis,it can be inferred that rockburst disasters involve three main problems,i.e.,the induction factors are complicated,the mechanism is still unclear,and the accuracy of the monitoring equipment and multi-source stereo monitoring technology is insufficient.The monitoring and warning standards of rockburst need to be further clarified and im-proved.Combined with the Internet of Things,cloud computing,and big data,a study of the trend of rockburst needs to be conducted.Further-more,the mechanism of multiphase and multi-field coupling induced by rockburst on a large scale needs to be explored.A multisystem and multiparameter integrated monitoring and early warning system and remote monitoring cloud platform for rockburst should be explored and developed.High-reliability sensing technology and equipment and perfect monitoring and early warning standards are considered to be the de-velopment direction of rockburst in the future.This research will help experts and technicians adopt effective measures for controlling rock-burst disasters.

Review of Power Supply and Distribution Construction Technology for Highway Electromechanical Engineering

In recent years,China has made significant progress in the construction of highways,resulting in an improved highway network that has provided robust support for economic and social development.However,the rapid expansion of highway construction,power supply,and distribution has led to several challenges in mechanical and electrical engineering technology.Ensuring the safe,stable,and cost-effective operation of the power supply and distribution system to meet the diverse requirements of highway operations has become a pressing issue.This article takes an example of a highway electromechanical engineering power supply and distribution construction project to provide insight into the construction process of highway electromechanical engineering power supply and distribution technology.

Failure mechanism of bolting support and high-strength bolt-grouting technology for deep and soft surrounding rock with high stress

In deep underground mining, the surrounding rocks are very soft with high stress. Their deformation and destruction are serious, and frequent failures occur on the bolt support. The failure mechanism of bolt support is proposed to solve these problems. A calculation theory is established on the bond strength of the interface between the anchoring agent and surrounding rocks. An analysis is made on the influence law of different mechanical parameters of surrounding rocks on the interfacial bond strength. Based on the research, a new high-strength bolt-grouting technology is developed and applied on site. Besides, some helpful engineering suggestions and measures are proposed. The research shows that the serious deformation and failure, and the lower bond strength are the major factors causing frequent failures of bolt support. So, the bolt could not give full play to its supporting potential. It is also shown that as the integrity, strength, interface dilatancy and stress of surrounding rocks are improved, the bond strength will increase. So, the anchoring force on surrounding rocks can be effectively improved by employing an anchoring agent with high sand content, mechanical anchoring means, or grouting reinforcement. The new technology has advantages in a high strength, imposing pre-tightening force, and giving full play to the bolt supporting potential. Hence, it can improve the control effect on surrounding rocks. All these could be helpful references for the design of bolt support in deep underground mines.

Instability mechanism and control technology of soft rock roadway affected by mining and high confined water

Based on deformation and failure characteristics of the second belt conveyor roadway at level II of Zhuxianzhuang coal mine, laboratory experiments, numerical calculation and field test were adopted to analyze the composition and microstructure of mudstone, the law of mudstone hydration and its strength weakening induced by water, the characteristics of surrounding rock deformation and failure under the action of confined water. Results showed that montmorillonite clay minerals accounted for as much as 76% of mudstone, with a large number of pores existing in the microstructure. Besides, as the molecular structure of montmorillonite changed, mudstone microstructure damage occurred with the macroscopic manifestation of its theological instability. Weakening degree of confined water on residual strength of mudstone was almost 50%. The instability mechanism of soft rock roadway caused by high confined water is that surrounding rock circulates the process of ＂fracture-seepage-mud ding-closed＂ twice, which weakens its strength and leads to roadway instability. A combined support technology, namely the, ＂high-toughness sealing layer ＋ hollow grouting cables ＋ full-length anchoring bolts with deep borehole＂ was proposed. Based on field observation, the soft rock roadway was controlled effectively, which also verified the effectiveness of new control technology for surrounding rock.

Neural mechanism of proposer's decision-making in the ultimatum and dictator games

Previous studies have demonstrated that reactions to unfair offers in the ultimatum game are correlated with negative emotion. However, little is known about the difference in neural activity between a proposer＇s decision-making in the ultimatum game compared with the dictator game. The present functional magnetic resonance imaging study revealed that proposing fair offers in the dictator game elicited greater activation in the right supramarginal gyrus, right medial frontal gyrus and left anterior cingulate cortex compared with proposing fair offers in the ultimatum game in 23 Chinese undergraduate and graduate students from Beijing Normal University in China. However, greater activation was found in the right superior temporal gyrus and left cingulate gyrus for the reverse contrast. ＂The results indicate that proposing fair offers in the dictator game is more strongly associated with cognitive control and conflicting information processing compared with proposing fair offers in the ultimatum game.

Joint Bearing Mechanism of Coal Pillar and Backfilling Body in Roadway Backfilling Mining Technology

In the traditional mining technology,the coal resources trapped beneath surface buildings,railways,and water bodies cannot be mined massively,thereby causing the lower coal recovery and dynamic disasters.In order to solve the aforementioned problems,the roadway backfilling mining technology is developed and the joint bearing mechanism of coal pillar and backfilling body is presented in this paper.The mechanical model of bearing system of coal pillar and backfilling body is established,by analyzing the basic characteristics of overlying strata deformation in roadway backfilling mining technology.According to the Ritz method in energy variation principle,the elastic solution expression of coal pillar deformation is deduced in roadway backfilling mining technology.Based on elastic-viscoelastic correspondence principle,combining with the burgers rheological constitutive model and Laplace transform theory,the viscoelastic solution expression of coal pillar deformation is obtained in roadway backfilling mining technology.By analyzing the compressive mechanical property of backfilling body,the time formula required for coal pillar and backfilling body to play the joint bearing function in roadway backfilling mining technology is obtained.The example analysis indicates that the time is 140 days.The results can be treated as an important basis for theoretical research and process design in roadway backfilling mining technology.

Mechanism and Preventive Technology of the Thaumasite Form of Sulfate Attack on Cement Mortars

The deterioration mechanism of thaumasite towards cement or concrete structure and the deterioration pattern of in-situ construction caused by the formation of thaumasite were studied in this paper. To improve the TSA (the thaumasite form of sulfate attack) resistance, the cement type, water to cement ratios, the mineral admixture and the circumstance factors should be taken into consideration.

Study on Technology and Mechanism of Purifying Scandium Metal by Vacuum Distillation Method

The evaporation coefficients alpha(i) of impurity elements Al, Cu, Cr, Co, Fe, Ni, Si in liquid scandium metal of purity 99.9% were measured at 1550 degrees C and 6.7 x 10(-3) Pa. The separating coefficients beta(i) and activity coefficients gamma(i)(o) of these impurity elements were calculated and the separation possibility between these impurity elements and Sc was discussed from thermodynamics. Then the new technology in preparation of high purity scandium metal was proposed and its purification mechanism was discussed.

The modulation recognition based on decision-making mechanism and neural network integrated classifier

A neural network integrated classifier(NNIC) designed with a new modulation recognition algorithm based on the decision-making tree is proposed in this paper.Firstly,instantaneous parameters are extracted in the time domain by the coordinated rotation digital computer(CORDIC) algorithm based on the extended convergence domain and feature parameters of frequency spectrum and power spectrum are extracted by the time-frequency analysis method.All pattern identification parameters are calculated under the I/Q orthogonal two-channel structure,and constructed into the feature vector set.Next,the classifier is designed according to the modulation pattern and recognition performance of the feature parameter set,the optimum threshold is selected for each feature parameter based on the decision-making mechanism in a single classifier,multi-source information fusion and modulation recognition are realized based on feature parameter judge process in the NNIC.Simulation results show NNIC is competent for all modulation recognitions,8 kinds of digital modulated signals are effectively identified,which shows the recognition rate and anti-interference capability at low SNR are improved greatly,the overall recognition rate can reach 100%when SNR is12dB.

Mechanism of realizing industrial structure upgrading through technology-driven regional innovation capacity

Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of regional innovation capacity. It points out that the essential of regional industrial structure upgrading is the transition of regional technology structure from one balance to another. The mechanism of realizing industrial structure upgrading through technology-driven regional innovation capacity is also discussed briefly.

Research on the Communication Mechanism of Online Rumors Under the Empowerment of New Media Technology-Take the“Nabobess Having an Affair With Courier”Rumor Incident as an Example

As new media communication becomes popular and the technological threshold of personal expression has been lowered,the phenomenon of online rumors has also emerged with new communication characteristics as individuals are continuously empowered to communicate.This paper quantifies a rumor spreading event from 2020 to 2021 that generated a lot of discussion.Using a content analysis approach,we examined how different subjects in the online public opinion chaos have influenced the spreading process of the event,and used the study of online rumor spreading mechanism to gain insight into the public opinion governance in the new media era.The study found that media platforms,the parties involved,and the general public as important participants have fully utilized the voice channel of the online communication platform to play a role behind the rumor event.

Research on the potential mechanism of Huashi Baidu Recipe against novel coronavirus pneumonia(COVID-19)by network pharmacology and molecular docking technology

Objective:Use network pharmacology to explore the anti-COVID-19 mechanism of Huashi Baidu Recipe,supplemented by molecular docking verification.Methods:Thorugh databases such as TCMSP,GeneCard,String,and software such as Cytoscape,AutoDockVina,network relationships was established,and the binding ability of active ingredients and targets is calculated through molecular docking,and biological function enrichment analysis was conducted.Result:The ingredients in Huashi Baidu Recipe that had strong affinity with SARS-CoV-23CL hydrolase(3CLpro)and angiotensin converting enzyme 2(ACE2)receptors include Quercetin,Baicalein,Astragaloside IV,Wogonin and other ingredients;25 active ingredients which obtained by screening had strong affinity with targets such as IL6,IL1B,NOS2 and CCL2.The biological function enrichment analysis mainly focused on Th17,Th1 and Th2 cell differentiation,NF-κB,MAPK,TNF,IL-17signaling pathway,etc.Conclusion:The active ingredients of Huashi Baidu Recipe may inhibit the infection and replication of SARS-CoV-2 virus,regulate RAS system’balance,inhibit excessive immune inflammatory response,and prevent inflammatory storm from appearing to fight COVID-19.

Research on Incentive Mechanism and Analysis of the Obstacles in the Application of Low-carbon Logistics Technology

Low-carbon logistics technology is a modem technology with green environmental protection concept as the core, which can effectively reduce the carbon emissions of all links in logistics activities, and thus achieve the goal of maximizing the use of resources and reducing environmental pollution. With the deepening of the concept of environmental protection, the application of low-carbon logistics technology is not only an inevitable choice for adapting to social development and responding to environmental protection slogans, but also an inevitable choice for the logistics industry to achieve sustainable development goals. Based on the brief introduction of low-carbon logistics technology, this paper analyzes the main obstacles of the application of the technology, and proposes corresponding incentive mechanism according to the obstacle factors, aiming at alleviating the resistance in the practical application of low-carbon logistics technology and promoting the realization of low-carbon logistics development.

On Innovation of Coordinative Development Mechanism of Science and Technology Park with Surrounding Areas under Promotion of the Government——Case Study on Three Science and Technology Park in Dongguan

Science and Technology Park, which plays a very important role in promoting rapid development of regional economy, has enjoyed various preferential policies in its unique development since China’s reform and opening up, which oppositely shows that the government has overlooked development outside the park and resulted in negative competition between the science and technology park and surrounding areas in resources and industry development, etc. Therefore, it is necessary and urgent to overcome the existing obstacles against coordinative development between the park and surrounding areas, to explore paths where the two can development coordinately and to achieve new breakthrough and innovation in coordinative development in subject, object, platform and mechanism.

Research on the Action Mechanism of Technology Foresight in Strategic Emerging Industries----Take The Delphi Method And Technology Roadmap For Example

Developing strategic emerging industries is the major strategic initiative to accelerate the transformation of economic development while Technology Foresight is a very effective tool. This essay analyses the roles and limitations of Delphi method and Technology Roadmap in development of strategic emerging industries and offers suggestions on how to strengthen the effectiveness of Technology Foresight in it.

Research on the Action Mechanism of Technology Foresight in Strategic Emerging Industries --Take the Delphi Method and Technology Roadmap for Example

Developing strategic emerging industries is the major strategic initiative to accelerate the transformation of economic development while Technology Foresight is a very effective tool. This essay analyses the roles and limitations of Delphi method and Technology Roadmap in development of strategic emerging industries and offers suggestions on how to strengthen the effectiveness of Technology Foresight in it.