The female internal sex organs develop from the paramesonephric （Mullerian） duct. In male embryos, the regression of the Mullerian duct is caused by the anti-Mullerian hormone （AMH）, which plays an important role ...The female internal sex organs develop from the paramesonephric （Mullerian） duct. In male embryos, the regression of the Mullerian duct is caused by the anti-Mullerian hormone （AMH）, which plays an important role in the process of testicular descent. The physiological remnant of the Mullerian duct in males is the appendix testis （AT）. In our previous study, we presented evidence for the decreased incidence of AT in cryptorchidism with intraoperative surgery. In this report, the expression of the anti-Mullerian hormone receptor type 2 （AMHR2）, the specific receptor of AMH, on the AT was investigated in connection with different urological disorders, such as hernia inguinalis, torsion of AT, cysta epididymis, varicocele, hydrocele testis and various forms of undescended testis. The correlation between the age of the patients and the expression of the AMHR2 was also examined. Reverse transcriptase-polymerase chain reaction （RT-PCR） and immunohistochemistry were used to detect the receptor＇s mRNA and protein levels, respectively. We demonstrate that AMHR2 is expressed in the ATs. Additionally, the presence of this receptor was proven at the mRNA and protein levels. The expression pattern of the receptor correlated with neither the examined urological disorders nor the age of the patients; therefore, the function of the AT remains obscure.展开更多
目的探讨小儿腹腔镜和传统睾丸下降固定术的比较效果情况。方法便利选取茂名市妇幼保健院2017年1月-2019年9月收治的80例隐睾患儿作为观察对象,按照随机数字表法进行分组,对照组40例和观察组40例。观察两组隐睾患儿炎症水平、手术时间...目的探讨小儿腹腔镜和传统睾丸下降固定术的比较效果情况。方法便利选取茂名市妇幼保健院2017年1月-2019年9月收治的80例隐睾患儿作为观察对象,按照随机数字表法进行分组,对照组40例和观察组40例。观察两组隐睾患儿炎症水平、手术时间、手术过程中出血量、住院时间、临床疗效评价情况。结果两组隐睾患儿术前CRP、TNF-α、IL-6比较,差异无统计学意义(P>0.05),观察组术后1 d、术后14 d CRP (25.61±5.22)mg/L和(12.74±3.08)mg/L、TNF-α(184.25±54.73)ng/mL和(103.62±30.53)ng/mL、IL-6(360.53±30.42)pg/mL和(125.78±16.73)pg/mL均低于对照组(383.67±8.23)mg/L和(29.12±5.36)mg/L、(267.42±75.18)ng/mL和(198.46±52.18)ng/mL、(428.46±20.63)pg/mL和(367.26±30.42)pg/mL(t=6.927、14.923、5.697、9.283、9.823、30.928,P<0.05),观察组患儿手术过程中出血量(15.42±6.77)mL、住院时间(6.18±2.01)d均低于对照组(40.26±9.78)mL、(10.18±3.06)d(t=13.208、6.910,P<0.05),观察组患儿临床治疗总有效率100.00%高于对照组85.00%,差异有统计学意义(χ~2=16.216,P<0.05)。结论小儿腹腔镜睾丸下降固定术,创伤小,出血量少,炎性刺激小,恢复快,效果好。展开更多
文摘The female internal sex organs develop from the paramesonephric （Mullerian） duct. In male embryos, the regression of the Mullerian duct is caused by the anti-Mullerian hormone （AMH）, which plays an important role in the process of testicular descent. The physiological remnant of the Mullerian duct in males is the appendix testis （AT）. In our previous study, we presented evidence for the decreased incidence of AT in cryptorchidism with intraoperative surgery. In this report, the expression of the anti-Mullerian hormone receptor type 2 （AMHR2）, the specific receptor of AMH, on the AT was investigated in connection with different urological disorders, such as hernia inguinalis, torsion of AT, cysta epididymis, varicocele, hydrocele testis and various forms of undescended testis. The correlation between the age of the patients and the expression of the AMHR2 was also examined. Reverse transcriptase-polymerase chain reaction （RT-PCR） and immunohistochemistry were used to detect the receptor＇s mRNA and protein levels, respectively. We demonstrate that AMHR2 is expressed in the ATs. Additionally, the presence of this receptor was proven at the mRNA and protein levels. The expression pattern of the receptor correlated with neither the examined urological disorders nor the age of the patients; therefore, the function of the AT remains obscure.
文摘目的探讨小儿腹腔镜和传统睾丸下降固定术的比较效果情况。方法便利选取茂名市妇幼保健院2017年1月-2019年9月收治的80例隐睾患儿作为观察对象,按照随机数字表法进行分组,对照组40例和观察组40例。观察两组隐睾患儿炎症水平、手术时间、手术过程中出血量、住院时间、临床疗效评价情况。结果两组隐睾患儿术前CRP、TNF-α、IL-6比较,差异无统计学意义(P>0.05),观察组术后1 d、术后14 d CRP (25.61±5.22)mg/L和(12.74±3.08)mg/L、TNF-α(184.25±54.73)ng/mL和(103.62±30.53)ng/mL、IL-6(360.53±30.42)pg/mL和(125.78±16.73)pg/mL均低于对照组(383.67±8.23)mg/L和(29.12±5.36)mg/L、(267.42±75.18)ng/mL和(198.46±52.18)ng/mL、(428.46±20.63)pg/mL和(367.26±30.42)pg/mL(t=6.927、14.923、5.697、9.283、9.823、30.928,P<0.05),观察组患儿手术过程中出血量(15.42±6.77)mL、住院时间(6.18±2.01)d均低于对照组(40.26±9.78)mL、(10.18±3.06)d(t=13.208、6.910,P<0.05),观察组患儿临床治疗总有效率100.00%高于对照组85.00%,差异有统计学意义(χ~2=16.216,P<0.05)。结论小儿腹腔镜睾丸下降固定术,创伤小,出血量少,炎性刺激小,恢复快,效果好。
