Land use and land cover change as the core of coupled human-environment systems has become a potential field of land change science (LCS) in the study of global environmental change. Based on remotely sensed data of...Land use and land cover change as the core of coupled human-environment systems has become a potential field of land change science (LCS) in the study of global environmental change. Based on remotely sensed data of land use change with a spatial resolution of 1 km × 1 km on national scale among every 5 years, this paper designed a new dynamic regionalization according to the comprehensive characteristics of land use change including regional differentiation, physical, economic, and macro-policy factors as well. Spatial pattern of land use change and its driving forces were investigated in China in the early 21 st century. To sum up, land use change pattern of this period was characterized by rapid changes in the whole country. Over the agricultural zones, e.g., Huang-Huai-Hai Plain, the southeast coastal areas and Sichuan Basin, a great proportion of fine arable land were engrossed owing to considerable expansion of the built-up and residential areas, resulting in decrease of paddy land area in southern China. The development of oasis agriculture in Northwest China and the reclamation in Northeast China led to a slight increase in arable land area in northern China. Due to the "Grain for Green" policy, forest area was significantly increased in the middle and western developing regions, where the vegetation coverage was substantially enlarged, likewise. This paper argued the main driving forces as the implementation of the strategy on land use and regional development, such as policies of "Western Development", "Revitalization of Northeast", coupled with rapidly economic development during this period.展开更多
Objective The northern Guangxi region is in the southwestern part of the Southern China continent,which is located at the junction of the southwest section of the Early Paleozoic Yangtze block and Cathaysian block.A s...Objective The northern Guangxi region is in the southwestern part of the Southern China continent,which is located at the junction of the southwest section of the Early Paleozoic Yangtze block and Cathaysian block.A series of NNE-trending ductile shear zones are developed in this region,and these ductile shear zones are mostly previously suggested boundary faults of the Early Paleozoic Yangtze block and Cathaysian block,such as the Shoucheng–Piaoli ductile shear zone in Northern Guangxi (Meng Yuanku et al., 2016; Zhang Xuefeng et al., 2015).展开更多
Objective Several well-exposed gravity flow deposits in the Early Cretaceous Lingshandao Formation provide a rare opportunity to study deep-water processes. The main objective of this work is to establish the spatial...Objective Several well-exposed gravity flow deposits in the Early Cretaceous Lingshandao Formation provide a rare opportunity to study deep-water processes. The main objective of this work is to establish the spatial and temporal relationships between the various gravity flow deposits, and thus to establish their sequence stratigraphic patterns and depositional conditions.展开更多
Objective The Yingyangguan Group is widely exposed in the southwestern segment of boundary belt between Yangtze and Cathaysian blocks and is mainly composed of a suit of lower-grade metamorphic marine volcanoclastic-...Objective The Yingyangguan Group is widely exposed in the southwestern segment of boundary belt between Yangtze and Cathaysian blocks and is mainly composed of a suit of lower-grade metamorphic marine volcanoclastic- sedimentary rocks (Zhou Hanwen et al., 2002). Its forming age and petrogenesis are critical for better understanding the orogenic process and relationship of the Yangtze and Cathaysian blocks since the Neoproterozoic. However, few zircon U-Pb ages of samples from the Yingyangguan Group have been reported, which are much debated, such as the metamorphic spilite (819±11 Ma), keratophyre (415.1±2.1 Ma) and ignimbrite (821.3±3.9 Ma) (Tian Yang et al., 2015 and references in). In this study, we focus on the new discovered Early Yanshannian monzogranite and its mafic enclaves from the Yingyangguan Group, and conducted zircon U-Pb dating and in-situ Hf isotopic analyses to constrain their petrogenesis.展开更多
1 Introduction During the late Mesozoic times,the SE China is characterized by extensive magmatism and mineralization.The widely distributed granitoids with different(I-,S-and A-)types have been inferred to be closely...1 Introduction During the late Mesozoic times,the SE China is characterized by extensive magmatism and mineralization.The widely distributed granitoids with different(I-,S-and A-)types have been inferred to be closely related to the large-scale polymetallic mineralization.The Nanling tungsten-tin polymetallic belt is endowed with considerable展开更多
Objective The nearly parallel N-S-trending rifts in southern Tibet represent the E-W extension of the Tibet Plateau. Most data which constrained the age of the extensional deformation come from isotopic dating of the...Objective The nearly parallel N-S-trending rifts in southern Tibet represent the E-W extension of the Tibet Plateau. Most data which constrained the age of the extensional deformation come from isotopic dating of the dikes probably related to the activity of the nearly N-S faulting and micas from hydrothermal activity and the low- temperature thermochronology of plateau uplift. Previous research shows that there are at least three different ideas about the age of the rifts: (1) older than 16-12 Ma, (2) 14- 10 Ma, and (3) 8-4 Ma (Fig. la). For the old sedimentary strata represented the beginning of the rifting, the dating of the sediments helps to better define the initial rifting age.展开更多
1 Introduction Voluminous Mesozoic magmatic rocks containing abundant Au-Mo polymetallic mineralization resources are developed in the Xiaoqinling-Xiong’ershan district of the southern margin of the North China Crato...1 Introduction Voluminous Mesozoic magmatic rocks containing abundant Au-Mo polymetallic mineralization resources are developed in the Xiaoqinling-Xiong’ershan district of the southern margin of the North China Craton(NCC).展开更多
Objective Understanding the dynamics of sediment gravity flows is of great importance to correctly interpret their related deposits. The discovery of supercritical sediment gravity flows provides some new viewpoints ...Objective Understanding the dynamics of sediment gravity flows is of great importance to correctly interpret their related deposits. The discovery of supercritical sediment gravity flows provides some new viewpoints for the explanation of controversial sediment gravity flow deposits. However, the dynamics, formation, evolution processes of supercritical sediment gravity flows and their recognition criteria from their associated deposits are still worldwide controversial. The supercritical hyperpycnal flow deposits recognized in the upper part of Early Cretaceous Lingshandao Formation provide a rare opporttmity to understand their sedimentary characteristics. This work is aimed at documenting the typical sedimentary structures associated with the supercritical hyperpycnal flow, and discussing the vertical stacking and its relationship with flow evolution.展开更多
The Jiangshan-Shaoxing fault zone (JSFZ) was formed by the amalgamation of the Yangtze and Cathaysia blocks in the Neoproterozoic.Since the Paleozoic,the JSFZ has experienced three episodes of tectonic activities:t...The Jiangshan-Shaoxing fault zone (JSFZ) was formed by the amalgamation of the Yangtze and Cathaysia blocks in the Neoproterozoic.Since the Paleozoic,the JSFZ has experienced three episodes of tectonic activities:the Early Paleozoic ductile strike-slip shear,Early Mesozoic thrust,and the Late Mesozoic extension.展开更多
The amalgamation and breakup mechanisms of the Rodinia supercontinent during the Meso- and Neoproterozoic have been the focus of much research. However, few studies have examined the response of Neoproterozoic tectoni...The amalgamation and breakup mechanisms of the Rodinia supercontinent during the Meso- and Neoproterozoic have been the focus of much research. However, few studies have examined the response of Neoproterozoic tectonics and magmatism along the northeastern margin of the Yangtze Plate to synchronous global events. The Qianliyan Uplift is located on the eastern margin of the Sulu orogenic belt in the ocean, but the tectonic affinity of the uplift and its relationship to the Sulu orogenic belt remains unclear. In this study, we investigated the formation age, geochemical characteristics, genesis type, and affinity of the granitic gneiss on Chaolian Island of the Qianliyan uplift and its tectonic significance.展开更多
The Early and Middle Triassic primary lower Yangtze sea basin was formed before the Yangtze and Sino. Korean blocks collided and were assembled. showing the characteristics of an open continental shelf.continental mar...The Early and Middle Triassic primary lower Yangtze sea basin was formed before the Yangtze and Sino. Korean blocks collided and were assembled. showing the characteristics of an open continental shelf.continental margin sea. In order to provide evidence useful for oil and gas exploration in the studied region, this paper centres on the features of the sediments and their facies framework in the basin and the sedimentation parameters such as the deposition rate, palaeotemperature, palaeosatinity, palaeodepth of water and palaeocurrents of the basin.展开更多
The Early Paleoproterozoic Monchegorsk Complex is exposed over an area of 550 km;and comprises two layered mafite–ultramafite intrusions:the Monchepluton of ultramafic and mafic rocks and the predominantly gabbroid
Water painting is a traditional Chinese painting style.The art work consists of the real transmission electron microscope(TEM)images of ordered semiconductor CdS
BACKGROUND: Insulin-like growth factor-I(IGF-1), as one of the important members of growth factor family, participants in the regulation of many physiological functions and behaviors, having very strong neuroprotec...BACKGROUND: Insulin-like growth factor-I(IGF-1), as one of the important members of growth factor family, participants in the regulation of many physiological functions and behaviors, having very strong neuroprotective effect. However, the expression of IGF-1 following cerebral ischemia/reperfusion is still disputed. OBJECTIVE: To observe the expression of IGF-1 and protein of corpora striata in ischemic side at the early stage of middle cerebral artery ischemia/reperfusion in rhesus monkey. DESIGN : A completely randomized grouping design, controlled animal experiment SETTING : Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University MATERIALS: ① Totally 17 rhesus monkeys , of either gender, aged 4 to 5 years, were enrolled . Seven rhesus monkeys observed with gene chip were randomly divided into 2 groups: sham operation group (n=3) and ischemia/reperfusion group 〈n=4〉. Ten rhesus monkeys observed with in situ hybridization and immunohistochemistry method were randomly divided into 2 groups: sham operation group 〈n=3 〉and ischemia/reperfusion group (n=7). Rhesus monkeys observed under microscope were divided into 2 groups: sham operation group (n=6) and ischamia/reperfusion group (n=-11).②Materials used in the experiment: cresyl violet (Sigma Company, America); immunohistochemical reagent kit ( Huamei Bio-engineering Company); In situ hybridization reagent kit (Boshide Bio-engineering Co.Ltd, Wuhan); 12 800 dots chip (Boxing Company, Shanghai). METHODS : This experiment was carried out at the Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University from January 2001 to December 2003.① The onset area of middle cerebral artery was blocked for 2 hours, middle cerebral artery ischemia/reperfusion models were created.② After ischemia/reperfusion for 24 hours, cerebral tissue sections of rhesus monkeys were prepared and stained with cresyl violet. Image analysis was performed with 5001W image analysis software. Morphological change of corpora striata of operative side was observed in the rhesus monkeys between two groups. Total RNA was extracted from cerebral tissue. ③ Detection of gene chip: Cy3-duTP and Cy5-duTP were used to respectively perform reverse transcription labeling. The sample was reversely transcribed into cDNA, then hybridized with cDNA of cerebral tissue. Genes with the separate absolute value of cy3 and cy5〉800, cY3/cy5 〉 2(high expression) or 〈 0.5 (low expression) were found out. Those were genes with differential expression. ④ The expressions of IGF-1 mRNA and protein level of corpora striata in ischemic side of rhe- sus monkeys were detected between sham operation group and ischemia/reperfusion group at 9 and 24 hours after ischemia/reperfusion with in situ hybridization method and immunohistochemical method. Brown granules were IGF-1 protein positive cells. ⑤ Analysis of variance was used in the difference comparison of measurement data among groups. MAIN OUTCOME MEASURES : ① Change of morphological structure of corpora striata at ischemic side in rhesus monkeys. ② Change of cerebral gene expression profiles at ischemia/reperfusion in rhesus monkeys between two groups.③ Expression of IGF-1 mRNA and protein level of corpora striata at ischemia/reperfu- sion in rhesus monkeys between two groups. RESULTS : ① Pathological change : Obvious pathological change of cerebral infarction appeared in the ischemia and reperfusion group, while there was no such pathological change in the sham operation group.② Change of gene expression profile : There were 4480 genes with difference expression in the ischemia/reperfusion group and sham-operation group, in which, 260 genes had high expression and their absolute value was over 800, and 63 genes had low expression, cy3/cy5 of IGF-1 was 0.379, being relative low ex- pression. ③ IGF-1 mRNA and protein positive cell counts in corpora striata at cerebral ischemic side[IGF-1 mRNA: 〈9.72±1.18),(9.11 ±0.76),(14.77±0.60) counts/field:lGF-1 protein: (15.11 ±1.83),(15.39±0.78), (34.62±0.97)counts/field, P 〈 0.05-0.01]. CONCLUSION: IGF-1 mRNA and protein are lowly expressed in middle cerebral artery of rhesus monkeys at ischemia/reperfusion.展开更多
The North Altyn has underwent a complex tectonic history in the Early Paleozoic and formed a number of orogenic gold deposits controlled by ductile to brittle shear zones adjacent to the southern side of the Northern ...The North Altyn has underwent a complex tectonic history in the Early Paleozoic and formed a number of orogenic gold deposits controlled by ductile to brittle shear zones adjacent to the southern side of the Northern Altyn Tagh fault e.g. the Dapinggou, Beiketan and Xiangyun. The Dapinggou gold deposit, a typical orogenic gold deposit in North Altyn, is predominantly hosted in the Precambrian carbonate and Cambrian volcano- sedimentary rocks which were strongly deformed and were subjected to low-grade metamorphism. The ore bodies occurred in K-feldspar quartz veins and hydrothermally altered mylonite within the ductile shear belt. Hydrothermal alteration including silicification, pyritization.展开更多
Four Changes in World EconomyFirst,a new round of global economic growth is under way.In 2000,oil pricerose rapidly,stoek markets and exchange rates remained volatile and interestrates went up.All these disadvantages ...Four Changes in World EconomyFirst,a new round of global economic growth is under way.In 2000,oil pricerose rapidly,stoek markets and exchange rates remained volatile and interestrates went up.All these disadvantages did not undermine the foundations of worldeconomy,and the average growth rate of global gross domestic product(GDP)展开更多
Along with the ring of the millennium bell, the human society has entered a new century, and China’s national rejuvenation has come into a new stage. Undoubtedly, the coming ten years are of great significance becaus...Along with the ring of the millennium bell, the human society has entered a new century, and China’s national rejuvenation has come into a new stage. Undoubtedly, the coming ten years are of great significance because they will serve as a link between the past and the future. During this period, further deepening of revolution in science and technology represented by information technology and展开更多
Ⅰ.INTRODUCTION AND BACKGROUNDIn the introduction of her recent book on Ur-Namma in the Sumerian literarytradition,E. Flckiger-Hawker offers a comprehensive account and summary ofthe previous scholarship of the compli...Ⅰ.INTRODUCTION AND BACKGROUNDIn the introduction of her recent book on Ur-Namma in the Sumerian literarytradition,E. Flckiger-Hawker offers a comprehensive account and summary ofthe previous scholarship of the complicated political history between the fall ofthe Akkadian empire and the beginning of the Ur Ⅲ period.From this account,itbecomes clear that this scholarship primarily relies on various interpretations展开更多
The relationship between Egypt and Palestine can be traced back to theChalcolithic Age thanks to the evidence of current excavations in the Nile Deltaand Sinal.Palestinian pottery and cast metal objects from the Delta...The relationship between Egypt and Palestine can be traced back to theChalcolithic Age thanks to the evidence of current excavations in the Nile Deltaand Sinal.Palestinian pottery and cast metal objects from the Delta sites of Maadi,Minshat Abu Omar,and elsewhere have proved contacts with Palestine inProtodynastic(Nagada Ⅱ-Ⅲ)times.The Egyptian Protodynastic Period andDynasty 1 were contemporary with the Palestinian EB Ⅰ and EB Ⅲ,and展开更多
基金National Basic Research Program of China, No.2009CB421105National Key Technology R&D Program, No.2006BAC08B00Knowledge Innovation Program of the CAS, No.KSCX1-YW-09-01
文摘Land use and land cover change as the core of coupled human-environment systems has become a potential field of land change science (LCS) in the study of global environmental change. Based on remotely sensed data of land use change with a spatial resolution of 1 km × 1 km on national scale among every 5 years, this paper designed a new dynamic regionalization according to the comprehensive characteristics of land use change including regional differentiation, physical, economic, and macro-policy factors as well. Spatial pattern of land use change and its driving forces were investigated in China in the early 21 st century. To sum up, land use change pattern of this period was characterized by rapid changes in the whole country. Over the agricultural zones, e.g., Huang-Huai-Hai Plain, the southeast coastal areas and Sichuan Basin, a great proportion of fine arable land were engrossed owing to considerable expansion of the built-up and residential areas, resulting in decrease of paddy land area in southern China. The development of oasis agriculture in Northwest China and the reclamation in Northeast China led to a slight increase in arable land area in northern China. Due to the "Grain for Green" policy, forest area was significantly increased in the middle and western developing regions, where the vegetation coverage was substantially enlarged, likewise. This paper argued the main driving forces as the implementation of the strategy on land use and regional development, such as policies of "Western Development", "Revitalization of Northeast", coupled with rapidly economic development during this period.
基金funded by the National Natural Science Foundation of China(grants No.41572191 and 41702211)the Natural Science Foundation of Guangxi(grant No.2017GXNSFBA198166)
文摘Objective The northern Guangxi region is in the southwestern part of the Southern China continent,which is located at the junction of the southwest section of the Early Paleozoic Yangtze block and Cathaysian block.A series of NNE-trending ductile shear zones are developed in this region,and these ductile shear zones are mostly previously suggested boundary faults of the Early Paleozoic Yangtze block and Cathaysian block,such as the Shoucheng–Piaoli ductile shear zone in Northern Guangxi (Meng Yuanku et al., 2016; Zhang Xuefeng et al., 2015).
基金supported by the National Natural Science Foundation of China(grant No.41372135)Shandong University of Science and Technology Research Fund(grant No.2015TDJH101)
文摘Objective Several well-exposed gravity flow deposits in the Early Cretaceous Lingshandao Formation provide a rare opportunity to study deep-water processes. The main objective of this work is to establish the spatial and temporal relationships between the various gravity flow deposits, and thus to establish their sequence stratigraphic patterns and depositional conditions.
基金financially supported by the China Geological Survey(grants No.12120113063200 and DD20160035-1)
文摘Objective The Yingyangguan Group is widely exposed in the southwestern segment of boundary belt between Yangtze and Cathaysian blocks and is mainly composed of a suit of lower-grade metamorphic marine volcanoclastic- sedimentary rocks (Zhou Hanwen et al., 2002). Its forming age and petrogenesis are critical for better understanding the orogenic process and relationship of the Yangtze and Cathaysian blocks since the Neoproterozoic. However, few zircon U-Pb ages of samples from the Yingyangguan Group have been reported, which are much debated, such as the metamorphic spilite (819±11 Ma), keratophyre (415.1±2.1 Ma) and ignimbrite (821.3±3.9 Ma) (Tian Yang et al., 2015 and references in). In this study, we focus on the new discovered Early Yanshannian monzogranite and its mafic enclaves from the Yingyangguan Group, and conducted zircon U-Pb dating and in-situ Hf isotopic analyses to constrain their petrogenesis.
基金Funding for the project is provided by the China Geological Survey(NO. 121201004000150015 and NO. 12120115037101)
文摘1 Introduction During the late Mesozoic times,the SE China is characterized by extensive magmatism and mineralization.The widely distributed granitoids with different(I-,S-and A-)types have been inferred to be closely related to the large-scale polymetallic mineralization.The Nanling tungsten-tin polymetallic belt is endowed with considerable
基金supported by the National Natural Science Foundation of China(grant No.41571013)Project of China Geological Survey(grant No.12120114002101)
文摘Objective The nearly parallel N-S-trending rifts in southern Tibet represent the E-W extension of the Tibet Plateau. Most data which constrained the age of the extensional deformation come from isotopic dating of the dikes probably related to the activity of the nearly N-S faulting and micas from hydrothermal activity and the low- temperature thermochronology of plateau uplift. Previous research shows that there are at least three different ideas about the age of the rifts: (1) older than 16-12 Ma, (2) 14- 10 Ma, and (3) 8-4 Ma (Fig. la). For the old sedimentary strata represented the beginning of the rifting, the dating of the sediments helps to better define the initial rifting age.
基金supported by the NSFC (41373039)the DREAM project of MOST, China (2016YFC0600403)
文摘1 Introduction Voluminous Mesozoic magmatic rocks containing abundant Au-Mo polymetallic mineralization resources are developed in the Xiaoqinling-Xiong’ershan district of the southern margin of the North China Craton(NCC).
基金the National Science Foundation of China (grant No.U1262203)the National Science and Technology Special Grant (grant No.2016ZX05006-007) for their financial support
文摘Objective Understanding the dynamics of sediment gravity flows is of great importance to correctly interpret their related deposits. The discovery of supercritical sediment gravity flows provides some new viewpoints for the explanation of controversial sediment gravity flow deposits. However, the dynamics, formation, evolution processes of supercritical sediment gravity flows and their recognition criteria from their associated deposits are still worldwide controversial. The supercritical hyperpycnal flow deposits recognized in the upper part of Early Cretaceous Lingshandao Formation provide a rare opporttmity to understand their sedimentary characteristics. This work is aimed at documenting the typical sedimentary structures associated with the supercritical hyperpycnal flow, and discussing the vertical stacking and its relationship with flow evolution.
基金funded by the National Science and Technology Major Project (2008ZX05005–001)China Geological Survey Project (Grant No.1212011120160)
文摘The Jiangshan-Shaoxing fault zone (JSFZ) was formed by the amalgamation of the Yangtze and Cathaysia blocks in the Neoproterozoic.Since the Paleozoic,the JSFZ has experienced three episodes of tectonic activities:the Early Paleozoic ductile strike-slip shear,Early Mesozoic thrust,and the Late Mesozoic extension.
基金funded by the National Natural Science Foundation of China(grants No.41406080,41273066 and 41106060)China Geological Survey(grant No.DD20160155)
文摘The amalgamation and breakup mechanisms of the Rodinia supercontinent during the Meso- and Neoproterozoic have been the focus of much research. However, few studies have examined the response of Neoproterozoic tectonics and magmatism along the northeastern margin of the Yangtze Plate to synchronous global events. The Qianliyan Uplift is located on the eastern margin of the Sulu orogenic belt in the ocean, but the tectonic affinity of the uplift and its relationship to the Sulu orogenic belt remains unclear. In this study, we investigated the formation age, geochemical characteristics, genesis type, and affinity of the granitic gneiss on Chaolian Island of the Qianliyan uplift and its tectonic significance.
文摘The Early and Middle Triassic primary lower Yangtze sea basin was formed before the Yangtze and Sino. Korean blocks collided and were assembled. showing the characteristics of an open continental shelf.continental margin sea. In order to provide evidence useful for oil and gas exploration in the studied region, this paper centres on the features of the sediments and their facies framework in the basin and the sedimentation parameters such as the deposition rate, palaeotemperature, palaeosatinity, palaeodepth of water and palaeocurrents of the basin.
文摘The Early Paleoproterozoic Monchegorsk Complex is exposed over an area of 550 km;and comprises two layered mafite–ultramafite intrusions:the Monchepluton of ultramafic and mafic rocks and the predominantly gabbroid
文摘Water painting is a traditional Chinese painting style.The art work consists of the real transmission electron microscope(TEM)images of ordered semiconductor CdS
基金the Natural Science Foundation of Shandong Province, No. Y2004C04
文摘BACKGROUND: Insulin-like growth factor-I(IGF-1), as one of the important members of growth factor family, participants in the regulation of many physiological functions and behaviors, having very strong neuroprotective effect. However, the expression of IGF-1 following cerebral ischemia/reperfusion is still disputed. OBJECTIVE: To observe the expression of IGF-1 and protein of corpora striata in ischemic side at the early stage of middle cerebral artery ischemia/reperfusion in rhesus monkey. DESIGN : A completely randomized grouping design, controlled animal experiment SETTING : Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University MATERIALS: ① Totally 17 rhesus monkeys , of either gender, aged 4 to 5 years, were enrolled . Seven rhesus monkeys observed with gene chip were randomly divided into 2 groups: sham operation group (n=3) and ischemia/reperfusion group 〈n=4〉. Ten rhesus monkeys observed with in situ hybridization and immunohistochemistry method were randomly divided into 2 groups: sham operation group 〈n=3 〉and ischemia/reperfusion group (n=7). Rhesus monkeys observed under microscope were divided into 2 groups: sham operation group (n=6) and ischamia/reperfusion group (n=-11).②Materials used in the experiment: cresyl violet (Sigma Company, America); immunohistochemical reagent kit ( Huamei Bio-engineering Company); In situ hybridization reagent kit (Boshide Bio-engineering Co.Ltd, Wuhan); 12 800 dots chip (Boxing Company, Shanghai). METHODS : This experiment was carried out at the Institute of Cerebrovascular Disease, Affiliated Hospital of Medical College of Qingdao University from January 2001 to December 2003.① The onset area of middle cerebral artery was blocked for 2 hours, middle cerebral artery ischemia/reperfusion models were created.② After ischemia/reperfusion for 24 hours, cerebral tissue sections of rhesus monkeys were prepared and stained with cresyl violet. Image analysis was performed with 5001W image analysis software. Morphological change of corpora striata of operative side was observed in the rhesus monkeys between two groups. Total RNA was extracted from cerebral tissue. ③ Detection of gene chip: Cy3-duTP and Cy5-duTP were used to respectively perform reverse transcription labeling. The sample was reversely transcribed into cDNA, then hybridized with cDNA of cerebral tissue. Genes with the separate absolute value of cy3 and cy5〉800, cY3/cy5 〉 2(high expression) or 〈 0.5 (low expression) were found out. Those were genes with differential expression. ④ The expressions of IGF-1 mRNA and protein level of corpora striata in ischemic side of rhe- sus monkeys were detected between sham operation group and ischemia/reperfusion group at 9 and 24 hours after ischemia/reperfusion with in situ hybridization method and immunohistochemical method. Brown granules were IGF-1 protein positive cells. ⑤ Analysis of variance was used in the difference comparison of measurement data among groups. MAIN OUTCOME MEASURES : ① Change of morphological structure of corpora striata at ischemic side in rhesus monkeys. ② Change of cerebral gene expression profiles at ischemia/reperfusion in rhesus monkeys between two groups.③ Expression of IGF-1 mRNA and protein level of corpora striata at ischemia/reperfu- sion in rhesus monkeys between two groups. RESULTS : ① Pathological change : Obvious pathological change of cerebral infarction appeared in the ischemia and reperfusion group, while there was no such pathological change in the sham operation group.② Change of gene expression profile : There were 4480 genes with difference expression in the ischemia/reperfusion group and sham-operation group, in which, 260 genes had high expression and their absolute value was over 800, and 63 genes had low expression, cy3/cy5 of IGF-1 was 0.379, being relative low ex- pression. ③ IGF-1 mRNA and protein positive cell counts in corpora striata at cerebral ischemic side[IGF-1 mRNA: 〈9.72±1.18),(9.11 ±0.76),(14.77±0.60) counts/field:lGF-1 protein: (15.11 ±1.83),(15.39±0.78), (34.62±0.97)counts/field, P 〈 0.05-0.01]. CONCLUSION: IGF-1 mRNA and protein are lowly expressed in middle cerebral artery of rhesus monkeys at ischemia/reperfusion.
文摘The North Altyn has underwent a complex tectonic history in the Early Paleozoic and formed a number of orogenic gold deposits controlled by ductile to brittle shear zones adjacent to the southern side of the Northern Altyn Tagh fault e.g. the Dapinggou, Beiketan and Xiangyun. The Dapinggou gold deposit, a typical orogenic gold deposit in North Altyn, is predominantly hosted in the Precambrian carbonate and Cambrian volcano- sedimentary rocks which were strongly deformed and were subjected to low-grade metamorphism. The ore bodies occurred in K-feldspar quartz veins and hydrothermally altered mylonite within the ductile shear belt. Hydrothermal alteration including silicification, pyritization.
文摘Four Changes in World EconomyFirst,a new round of global economic growth is under way.In 2000,oil pricerose rapidly,stoek markets and exchange rates remained volatile and interestrates went up.All these disadvantages did not undermine the foundations of worldeconomy,and the average growth rate of global gross domestic product(GDP)
文摘Along with the ring of the millennium bell, the human society has entered a new century, and China’s national rejuvenation has come into a new stage. Undoubtedly, the coming ten years are of great significance because they will serve as a link between the past and the future. During this period, further deepening of revolution in science and technology represented by information technology and
文摘Ⅰ.INTRODUCTION AND BACKGROUNDIn the introduction of her recent book on Ur-Namma in the Sumerian literarytradition,E. Flckiger-Hawker offers a comprehensive account and summary ofthe previous scholarship of the complicated political history between the fall ofthe Akkadian empire and the beginning of the Ur Ⅲ period.From this account,itbecomes clear that this scholarship primarily relies on various interpretations
文摘The relationship between Egypt and Palestine can be traced back to theChalcolithic Age thanks to the evidence of current excavations in the Nile Deltaand Sinal.Palestinian pottery and cast metal objects from the Delta sites of Maadi,Minshat Abu Omar,and elsewhere have proved contacts with Palestine inProtodynastic(Nagada Ⅱ-Ⅲ)times.The Egyptian Protodynastic Period andDynasty 1 were contemporary with the Palestinian EB Ⅰ and EB Ⅲ,and