After the 21st century,high school history learning will focus on teachers promoting the twelve-year state education.In recent years,in line with the changes in the new 108-year social curriculum,supporting strategies...After the 21st century,high school history learning will focus on teachers promoting the twelve-year state education.In recent years,in line with the changes in the new 108-year social curriculum,supporting strategies have been proposed:such as literacy orientation,inquiry and practice,learning process archives,and the structural direction of the controversial Chinese history into East Asian history.Historical learning has indeed had a great impact on the people’s national spiritual education and the development of historical consciousness in Taiwan’s education policy.This is the reason Taiwan’s Ministry of Education strives to improve students’historical literacy and connotation application abilities.When developing a learning policy,both external and internal learning factors need to be considered.The external aspect deals with the reasons for learning:Is learning for the purpose of using or accumulating historical wisdom in daily life to learn from the past and the present,on the other hand,to test the content of the course and the degree of absorption;or is it specifically for exams or other enlightenment purposes.The internal aspect involves those most affected by the policy:students and teachers.After studying and observing high school history learning policies for decades,some alternative future visions for history learning were found in the method of reflection on future research-the conclusion is that history is interestingly revitalized,and the preferred future is thematic history.According to the famous futurology scholar Sohail Inayatuallah’s proposal:the causal layering model.It helps understand how Taiwan’s historical policies operate.And how teachers and students on the front line respond to changes and take future actions.The key is to change the future:in the process of building an alternative future,whether the internal and external mix has changed or whether you want to try new things and expand your horizons.In fact,the difficulty of teaching lies in students’cooperation and conscious learning.Therefore,in the analysis of learning through alternative futures,is it possible to distinguish between internal and external situations and methods such as:1.Internal:Is education centered on teachers?Or is it student-centered?2.External:Does the Ministry of Education prioritize testing,or encourage teachers to adopt interactive communication and integrate education into the curriculum?Therefore,what is the function and inspiration of studying high school history and life?If thematic history teaching is used:teachers can use thematic learning methods to help students focus on causal relationships,the causes of turning points,or the evolution process of the beginning and end of events.This is more advantageous for testing based on the application topic,and it is easy to test how much understanding and understanding of history?Has an activating effect.By studying history in high school,using the“CLA(Causal layered analysis)”method of future studies,you can enter the stage of worldview exploration with the goal of improving professional depth and emotional level,and use it in your own understanding and utilization of history.Based on research,some insights into the prospects and thinking of learning history in high schools are provided:1.Facing the impact of declining birthrate,Taiwan needs a macro perspective to improve its future competitiveness and look forward to a new perspective on world history,using futuristic cause-and-effect level analysis to combine world changes with daily life applications.2.The study of history in high schools should go into a systematic construction:understand its cause-and-effect relationships and global trends,so teachers play a professional and future role in controlling the use of new information and technology.3.In the future,humans may develop more“intelligent”needs.As a reference from history or to explore the preferred path for the future,there will also be a greater need to innovate and meet challenges.4.Studying high school history has entered the professional field.Through self-exploration,it can be transformed into life affairs and establish the concept and value of lifelong learning.5.In studying the“history of high school learning”,have new prospects for the future of education.Through professional knowledge such as“trend theory and causal hierarchy analysis”of futurology,pursue new horizons and visions,making future education full of hope and possibility.展开更多
The physical process of cumulative second-harmonic generation of Lamb waves propagating in a two-layered solid plate is presented by using the second-order perturbation and the technique of nonlinear reflection of aco...The physical process of cumulative second-harmonic generation of Lamb waves propagating in a two-layered solid plate is presented by using the second-order perturbation and the technique of nonlinear reflection of acoustic waves at an interface. In general, the cumulative second-harmonic generation of a dispersive guided wave propagation does not occur. However, the present paper shows that the second-harmonic of Lamb wave propagation arising from the nonlinear interaction of the partial bulk acoustic waves and the restriction of the three boundaries of the solid plates does have a cumulative growth effect if some conditions are satisfied. Through boundary condition and initial condition of excitation, the analytical expression of cumulative second-harmonic of Lamb waves propagation is determined. Numerical results show the cumulative effect of Lamb waves on second-harmonic field patterns.展开更多
AIM:To evaluate retinal nerve fiber layer thickness and retinal vascular caliber alterations in coal mine workers.METHODS:The community-based observational crosssectional study included 4004 participants of a subpopul...AIM:To evaluate retinal nerve fiber layer thickness and retinal vascular caliber alterations in coal mine workers.METHODS:The community-based observational crosssectional study included 4004 participants of a subpopulation of the Kailuan Study.All the study participants underwent structured interviews with a standardized questionnaire,fundus photography and spectral-domain optical coherence tomography(OCT)examinations performed by trained doctors.RESULTS:The retinal nerve fiber layer thickness was significantly higher(P=0.006)and the central macular thickness was lower in coal miners(n=659,51.0±7.8 y)as compared to the control(working above the ground;n=477,51.8±7.5 y;P=0.032).Additionally,the downhole workers showed a significantly thicker retinal artery(P=0.012)and vein diameters(P<0.001).In multivariable regression,a thicker retinal nerve fiber layer was associated with a higher cumulative silica dust exposure(P=0.005)after adjusting for younger age and larger spherical equivalent.In a reverse pattern,a higher cumulative silica dust exposure(P=0.004)was significantly associated with a thicker retinal nerve fiber layer after adjusting for age,high-density lipoproteins and uric acid.Wider retinal vein diameters were associated with higher cumulative silica dust exposure(P=0.036)after adjusting for younger age and larger spherical equivalent.CONCLUSION:The retinal vessels diameters and retinal nerve fiber layer thickness are significantly thicker in long term of coal mining.The results of our study indicate that underground working environment may lead to retinal vessel dilation and inflammation.Thus,ocular examination might be needed within coal miners in order to monitor the occupational eye health as well as the incidence and progression of eye diseases.展开更多
Objective To investigate cumulative results of chemosensitivity test using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl (MTT) assay in double-layer agarose. Methods A total of 2 491 patients with different kinds of cance...Objective To investigate cumulative results of chemosensitivity test using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl (MTT) assay in double-layer agarose. Methods A total of 2 491 patients with different kinds of cancers were enrolled in the study, in which 18 kinds of different anticancer drugs were used. A computer soft was used to get patients’ information from chemosensitivity testing database and patients’ charts. ResultsThe total evaluability rate was 82.7% (2 060/2 491). Among all agents, the efficiency rates of 5-Fu, MMC, DDP, BLM and CBP were higher than the efficiency rates of others. The response rate range of different cancer in vitro sensitivity by using MTT assay in double layer agarose were from 9.2% (biliary duct) to 37.5% (malignant lymphoma). For colon and rectum cancer, 5-Fu, DDP, MMC and BLM were more sensitive than other anti-tumor agents. For breast carcinomas, ACTD and DDP were more sensitive. For gastric cancer, 5-Fu, DDP and BLM were more sensitive. For leukemia, VM-26 and HHRT were more sensitive. ACM was more sensitive to kidney and MXT and BLM were more sensitive to pancreas cancer. For Lung cancer, DDP and EPI were more sensitive. Mean true positive rate, mean true negative rate, mean sensitivity, mean specificity and mean accuracy were 44%, 92%, 72%, 77%, and 76%, respectively. Conclusion Chemosensitivity tesing using the MTT assay in a double layer agarose was a very useful reference to chem-therapy.展开更多
Muddy water irrigation,an effective water-saving irrigation method,has been widely used in the Yellow River Basin in China.To investigate the effect of sand content on water infiltration and dense layer formation unde...Muddy water irrigation,an effective water-saving irrigation method,has been widely used in the Yellow River Basin in China.To investigate the effect of sand content on water infiltration and dense layer formation under one-dimensional vertical infiltration of muddy water,muddy water infiltration experiments were performed in the laboratory,and five sand contents of muddy water(S=0%,3%,6%,9%,and 12%)were used.Models were established to describe the relationship between the cumulative infiltration amount[I(t)]and the infiltration duration(t);the relationship among the migration distance of the wetting front(Z),S,and t;the thickness of the sedimentary layer[H(t)];and the relationship between S and t.The results revealed that I(t)and Z decreased significantly with the increase of sand contents,while H(t)increased significantly with the increase of sand contents.I(t)and Z were in the range of 7 cm and 20 cm for each treatment,respectively.The variation in I(t)with t fitted Kostiakov and Philip models,and the coefficients of determination were all greater than 0.99.With the increase in S,the infiltration coefficient gradually decreased,the infiltration index gradually increased,and the sorptivity gradually decreased.The particle composition of the sedimentary layer was similar to that of the argillaceous sediment,and the content of particles with a size of less than 2 mm in the sedimentary layer was lower than that of the argillaceous sediment.Compared with the original soil,the content of particles with a size of less than 0.05 mm and physical clay particles(diameter less than 0.01 mm)in the soil with an infiltration depth of 0-2 cm increased.The retention layer was from the topsoil to the infiltration depth of approximately 2 cm.This study can provide a scientific basis for further research on soil infiltration mechanisms under muddy water.展开更多
Erythronium japonicum is a representative species of spring ephemeral, forest floor plants in substitution forests in Japan. Seed germination tests were conducted to observe the effects of temperature, light, and mois...Erythronium japonicum is a representative species of spring ephemeral, forest floor plants in substitution forests in Japan. Seed germination tests were conducted to observe the effects of temperature, light, and moisture content on the germination of E. japonicum. E. japonicum seeds did not germinate at constant temperatures of 5°C, 10°C, 15°C, 20°C, or 25°C. Seeds germinated at 5°C and 10°C after storage at 20°C for 1 or 2 months. Seed germinability was affected by desiccation to only 40% moisture content. Seeds germinated well in both light and dark conditions. Conditions under the leaf litter layer showed unique characteristics of temperature, light, and moisture content. The temperature was around 20°C under the leaf litter layer, even though it was 30°C above. The moisture content under the leaf litter layer was higher than that above. The leaf litter blocked out the sunlight. The temperature of 20°C necessary for E. japonicum germination occurred below, but not above, the leaf litter layer. The avoidance of decreasing in germinability from reduced seed moisture content in a short time is consistent with the high moisture conditions under the leaf litter layer. The leaf litter layer plays an important role in providing optimal conditions of temperature, light, and moisture content for the germination of E. japonicum seeds.展开更多
A technique for analyzing the nonlinear generation of the cumulative second har-monics of generalized Lamb modes in a layered planar structure is developed. A theoretical model for nonlinear generalized Lamb mode prop...A technique for analyzing the nonlinear generation of the cumulative second har-monics of generalized Lamb modes in a layered planar structure is developed. A theoretical model for nonlinear generalized Lamb mode propagation in a layered planar structure has been established, based on a partial plane wave approach. The nonlinearity is treated as a second-order perturbation of the linear elastic response. This model reveals some interesting features of the physics of the cumulative second harmonic generation. Although Lamb mode propagation is dispersive in a layered structure, the results of this analysis show that the amplitudes of the second harmonics do accumulate with propagation distance under certain special conditions. On the basis of the boundary and initial conditions of excitation, the formal solution of the cumulative second harmonic has been derived. Using the formal solution, we have performed some numerical simulations and obtained the cumulative second harmonic field patterns, illus-trating the distortion effect along the propagation distance, as well as the dependence of the field patterns on the position of the excitation source.展开更多
文摘After the 21st century,high school history learning will focus on teachers promoting the twelve-year state education.In recent years,in line with the changes in the new 108-year social curriculum,supporting strategies have been proposed:such as literacy orientation,inquiry and practice,learning process archives,and the structural direction of the controversial Chinese history into East Asian history.Historical learning has indeed had a great impact on the people’s national spiritual education and the development of historical consciousness in Taiwan’s education policy.This is the reason Taiwan’s Ministry of Education strives to improve students’historical literacy and connotation application abilities.When developing a learning policy,both external and internal learning factors need to be considered.The external aspect deals with the reasons for learning:Is learning for the purpose of using or accumulating historical wisdom in daily life to learn from the past and the present,on the other hand,to test the content of the course and the degree of absorption;or is it specifically for exams or other enlightenment purposes.The internal aspect involves those most affected by the policy:students and teachers.After studying and observing high school history learning policies for decades,some alternative future visions for history learning were found in the method of reflection on future research-the conclusion is that history is interestingly revitalized,and the preferred future is thematic history.According to the famous futurology scholar Sohail Inayatuallah’s proposal:the causal layering model.It helps understand how Taiwan’s historical policies operate.And how teachers and students on the front line respond to changes and take future actions.The key is to change the future:in the process of building an alternative future,whether the internal and external mix has changed or whether you want to try new things and expand your horizons.In fact,the difficulty of teaching lies in students’cooperation and conscious learning.Therefore,in the analysis of learning through alternative futures,is it possible to distinguish between internal and external situations and methods such as:1.Internal:Is education centered on teachers?Or is it student-centered?2.External:Does the Ministry of Education prioritize testing,or encourage teachers to adopt interactive communication and integrate education into the curriculum?Therefore,what is the function and inspiration of studying high school history and life?If thematic history teaching is used:teachers can use thematic learning methods to help students focus on causal relationships,the causes of turning points,or the evolution process of the beginning and end of events.This is more advantageous for testing based on the application topic,and it is easy to test how much understanding and understanding of history?Has an activating effect.By studying history in high school,using the“CLA(Causal layered analysis)”method of future studies,you can enter the stage of worldview exploration with the goal of improving professional depth and emotional level,and use it in your own understanding and utilization of history.Based on research,some insights into the prospects and thinking of learning history in high schools are provided:1.Facing the impact of declining birthrate,Taiwan needs a macro perspective to improve its future competitiveness and look forward to a new perspective on world history,using futuristic cause-and-effect level analysis to combine world changes with daily life applications.2.The study of history in high schools should go into a systematic construction:understand its cause-and-effect relationships and global trends,so teachers play a professional and future role in controlling the use of new information and technology.3.In the future,humans may develop more“intelligent”needs.As a reference from history or to explore the preferred path for the future,there will also be a greater need to innovate and meet challenges.4.Studying high school history has entered the professional field.Through self-exploration,it can be transformed into life affairs and establish the concept and value of lifelong learning.5.In studying the“history of high school learning”,have new prospects for the future of education.Through professional knowledge such as“trend theory and causal hierarchy analysis”of futurology,pursue new horizons and visions,making future education full of hope and possibility.
基金Project supported by the Shanghai Leading Academic Discipline Project, China (Grant No B503)
文摘The physical process of cumulative second-harmonic generation of Lamb waves propagating in a two-layered solid plate is presented by using the second-order perturbation and the technique of nonlinear reflection of acoustic waves at an interface. In general, the cumulative second-harmonic generation of a dispersive guided wave propagation does not occur. However, the present paper shows that the second-harmonic of Lamb wave propagation arising from the nonlinear interaction of the partial bulk acoustic waves and the restriction of the three boundaries of the solid plates does have a cumulative growth effect if some conditions are satisfied. Through boundary condition and initial condition of excitation, the analytical expression of cumulative second-harmonic of Lamb waves propagation is determined. Numerical results show the cumulative effect of Lamb waves on second-harmonic field patterns.
基金Supported by Science and Technology Project of Beijing Municipal Science and Technology Commission(No.Z181100001818003)The Capital Health Research and Development of Special(No.2020-1-2052)。
文摘AIM:To evaluate retinal nerve fiber layer thickness and retinal vascular caliber alterations in coal mine workers.METHODS:The community-based observational crosssectional study included 4004 participants of a subpopulation of the Kailuan Study.All the study participants underwent structured interviews with a standardized questionnaire,fundus photography and spectral-domain optical coherence tomography(OCT)examinations performed by trained doctors.RESULTS:The retinal nerve fiber layer thickness was significantly higher(P=0.006)and the central macular thickness was lower in coal miners(n=659,51.0±7.8 y)as compared to the control(working above the ground;n=477,51.8±7.5 y;P=0.032).Additionally,the downhole workers showed a significantly thicker retinal artery(P=0.012)and vein diameters(P<0.001).In multivariable regression,a thicker retinal nerve fiber layer was associated with a higher cumulative silica dust exposure(P=0.005)after adjusting for younger age and larger spherical equivalent.In a reverse pattern,a higher cumulative silica dust exposure(P=0.004)was significantly associated with a thicker retinal nerve fiber layer after adjusting for age,high-density lipoproteins and uric acid.Wider retinal vein diameters were associated with higher cumulative silica dust exposure(P=0.036)after adjusting for younger age and larger spherical equivalent.CONCLUSION:The retinal vessels diameters and retinal nerve fiber layer thickness are significantly thicker in long term of coal mining.The results of our study indicate that underground working environment may lead to retinal vessel dilation and inflammation.Thus,ocular examination might be needed within coal miners in order to monitor the occupational eye health as well as the incidence and progression of eye diseases.
文摘Objective To investigate cumulative results of chemosensitivity test using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl (MTT) assay in double-layer agarose. Methods A total of 2 491 patients with different kinds of cancers were enrolled in the study, in which 18 kinds of different anticancer drugs were used. A computer soft was used to get patients’ information from chemosensitivity testing database and patients’ charts. ResultsThe total evaluability rate was 82.7% (2 060/2 491). Among all agents, the efficiency rates of 5-Fu, MMC, DDP, BLM and CBP were higher than the efficiency rates of others. The response rate range of different cancer in vitro sensitivity by using MTT assay in double layer agarose were from 9.2% (biliary duct) to 37.5% (malignant lymphoma). For colon and rectum cancer, 5-Fu, DDP, MMC and BLM were more sensitive than other anti-tumor agents. For breast carcinomas, ACTD and DDP were more sensitive. For gastric cancer, 5-Fu, DDP and BLM were more sensitive. For leukemia, VM-26 and HHRT were more sensitive. ACM was more sensitive to kidney and MXT and BLM were more sensitive to pancreas cancer. For Lung cancer, DDP and EPI were more sensitive. Mean true positive rate, mean true negative rate, mean sensitivity, mean specificity and mean accuracy were 44%, 92%, 72%, 77%, and 76%, respectively. Conclusion Chemosensitivity tesing using the MTT assay in a double layer agarose was a very useful reference to chem-therapy.
基金the National Natural Science Foundation of China(Grant No.52079105 and 51779205)the Doctoral Dissertations Innovation Fund of Xi’an University of Technology(Grant No.310-252072107).
文摘Muddy water irrigation,an effective water-saving irrigation method,has been widely used in the Yellow River Basin in China.To investigate the effect of sand content on water infiltration and dense layer formation under one-dimensional vertical infiltration of muddy water,muddy water infiltration experiments were performed in the laboratory,and five sand contents of muddy water(S=0%,3%,6%,9%,and 12%)were used.Models were established to describe the relationship between the cumulative infiltration amount[I(t)]and the infiltration duration(t);the relationship among the migration distance of the wetting front(Z),S,and t;the thickness of the sedimentary layer[H(t)];and the relationship between S and t.The results revealed that I(t)and Z decreased significantly with the increase of sand contents,while H(t)increased significantly with the increase of sand contents.I(t)and Z were in the range of 7 cm and 20 cm for each treatment,respectively.The variation in I(t)with t fitted Kostiakov and Philip models,and the coefficients of determination were all greater than 0.99.With the increase in S,the infiltration coefficient gradually decreased,the infiltration index gradually increased,and the sorptivity gradually decreased.The particle composition of the sedimentary layer was similar to that of the argillaceous sediment,and the content of particles with a size of less than 2 mm in the sedimentary layer was lower than that of the argillaceous sediment.Compared with the original soil,the content of particles with a size of less than 0.05 mm and physical clay particles(diameter less than 0.01 mm)in the soil with an infiltration depth of 0-2 cm increased.The retention layer was from the topsoil to the infiltration depth of approximately 2 cm.This study can provide a scientific basis for further research on soil infiltration mechanisms under muddy water.
文摘Erythronium japonicum is a representative species of spring ephemeral, forest floor plants in substitution forests in Japan. Seed germination tests were conducted to observe the effects of temperature, light, and moisture content on the germination of E. japonicum. E. japonicum seeds did not germinate at constant temperatures of 5°C, 10°C, 15°C, 20°C, or 25°C. Seeds germinated at 5°C and 10°C after storage at 20°C for 1 or 2 months. Seed germinability was affected by desiccation to only 40% moisture content. Seeds germinated well in both light and dark conditions. Conditions under the leaf litter layer showed unique characteristics of temperature, light, and moisture content. The temperature was around 20°C under the leaf litter layer, even though it was 30°C above. The moisture content under the leaf litter layer was higher than that above. The leaf litter blocked out the sunlight. The temperature of 20°C necessary for E. japonicum germination occurred below, but not above, the leaf litter layer. The avoidance of decreasing in germinability from reduced seed moisture content in a short time is consistent with the high moisture conditions under the leaf litter layer. The leaf litter layer plays an important role in providing optimal conditions of temperature, light, and moisture content for the germination of E. japonicum seeds.
基金the National Natural Science Foundation of China(No.10004016).
文摘A technique for analyzing the nonlinear generation of the cumulative second har-monics of generalized Lamb modes in a layered planar structure is developed. A theoretical model for nonlinear generalized Lamb mode propagation in a layered planar structure has been established, based on a partial plane wave approach. The nonlinearity is treated as a second-order perturbation of the linear elastic response. This model reveals some interesting features of the physics of the cumulative second harmonic generation. Although Lamb mode propagation is dispersive in a layered structure, the results of this analysis show that the amplitudes of the second harmonics do accumulate with propagation distance under certain special conditions. On the basis of the boundary and initial conditions of excitation, the formal solution of the cumulative second harmonic has been derived. Using the formal solution, we have performed some numerical simulations and obtained the cumulative second harmonic field patterns, illus-trating the distortion effect along the propagation distance, as well as the dependence of the field patterns on the position of the excitation source.