Reciprocity Relation between Alternative Gravity Formulas

We compare Newton’s force law of universal gravitation with a corrected simple approach based on Bhandari’s recently presented work, where the gravitation constant G is maintained. A reciprocity relation exists between both alternative gravity formulas with respect to the distances between mass centers. We conclude a one-to-one mapping of the two gravitational formulas. We don’t need Einstein’s construct of spacetime bending by matter.

AR、SKP2、SOX10、PD-L1及TIL表达在三阴性乳腺癌中的意义

目的:探索雄激素受体(androgen receptor,AR)、S期激酶相关蛋白2(S-phase kinase-associated protein 2,SKP2)、性别决定区Y相关的HMG盒含因子10(sry-related HMG box-containing factor 10,SOX10)、程序性死亡配体1(programmed death-ligand 1,PD-L1)及肿瘤浸润性淋巴细胞(tumor infiltrating lymphocyte,TIL)在三阴性乳腺癌(triple negative breast cancer,TNBC)表达与临床病理特征和预后的关系。方法:根据苏木精-伊红染色(hematoxylineosin, HE)染色切片评判109例TNBC瘤巢内TIL的比例,采用Leica Bond-Max全自动免疫组化仪检测TNBC组织中AR、SKP2、SOX10、PD-L1的表达。分析以上各生物指标与临床病理特征间的关系,并采用kaplan-Meier、Log-rank进行生存分析。结果:95例患者获得随访,中位随访时间为48个月,中位无病生存时间(disease-free survival, DFS)为42个月,中位总生存时间(overall survival, OS)48个月。在TNBC中,AR阳性表达与淋巴结转移阴性(P=0.009)、肿瘤最大径<2 cm(P=0.008)相关,TIL高表达与低级别TNBC相关(P=0.007),SKP2阳性表达与神经/脉管侵犯阳性(P=0.011)、高级别TNBC相关(P=0.002),SOX10阳性表达与淋巴结转移阳性(P=0.022)、高级别TNBC(P=0.005)相关,PD-L1阳性表达与淋巴结转移阳性(P=0.020)、神经/脉管侵犯阳性(P=0.006)、高级别TNBC(P=0.042)相关。生存分析显示,SKP2、SOX10阳性表达与更差的DFS(P=0.007、P<0.001)和OS(P=0.013、P<0.001)相关,TIL高表达与更好的DFS(P=0.016)及OS(P=0.004)相关。在生物表志物的联合表达中,AR+/SKP2-、AR+/SOX10-与更好的DFS(P=0.004、P<0.001)及OS(P=0.007、P=0.001)相关,SOX10+/低TIL、PD-L1+/低TIL与更差的DFS(P<0.001、P=0.008)及OS(P=0.001、P=0.002)相关,AR-/低TIL者具有更差的OS(P=0.014)。SKP2(HR=4.143,95%CI为1.578~10.875)、SOX10(HR=7.578,95%CI为2.067~27.782)的阳性表达是影响TNBC患者DFS的独立预后因子,SKP2(HR=3.758,95%CI为1.400~10.084)、SOX10(HR=5.131,95%CI为1.316~20.000)及TIL(HR=0.375,95%CI为0.154~0.917)的阳性表达是TNBC患者OS的独立预后因子(P均<0.05)。结论:在TNBC中,AR阳性、TIL高表达与具有更好预后的临床病理特征相关,SKP2、SOX10和PD-L1与具侵袭性的临床病理特征相关。SKP2、SOX10及TIL表达与TNBC预后相关,提示这些生物指标可能成为TNBC新的预后因子,同时它们也有可能成为潜在的治疗靶点。

Two-Dimensional Numerical Simulation of the DC Glow Discharge in the Normal Mode and with Einstein’s Relation of Electron Diffusivity

This paper presents an investigation of a DC glow discharge at low pressure in the normal mode and with Einstein＇s relation of electron diffusivity. Two-dimensional distributions in Cartesian geometry are presented in the stationary state, including electric potential, electron and ion densities, longitudinal and transverse electrics fields as well as electron temperature. Our results are compared with those obtained in existing literature. The model used in this work is based on the first three moments of Boltzmann＇s equation. They serve as the continuity equation, the momentum transfer and the energy equations. The set of equations for charged particles presented in monatomic argon gas are coupled in a self-consistent way with Poisson＇s equation. A parametric study varying the cathode voltage, gas pressure, and secondary electron emission coefficient predicts many of the well-known features of DC discharges.

Intensive care environment: Perspective of relatives of critically ill patient sustained by health technology

The intensive care unit(ICU)is a complex setting by nature,and some have described it as bizarre due to its numerous sirens that sound when anything is dangerous,constant activity,equipment,bright lights,and high fatality rate.The demands placed on nurses to care for critically ill patients in this environment frequently prevent nurses and other health‑care professionals from acknowledging the feelings of patient’s relatives or family caregivers,resulting in a hostile environment from the patient’s relative’s perspective.When a patient’s family enters the ICU,they feel that hospital administrators do little to nothing to alleviate their discomfort and fear.Despite research demonstrating the importance of providing a homely environment for patients’families,In Nigeria ICU is still far behind how a conventional ICU environment should be structured to accommodate patient’s relations in the unit.The goal of this study was to look at the patient’s relative’s perspective on providing care for a critically ill patient in an ICU,with a focus on the unit’s complexity and overall experience.Based on the findings of this study,we recommend that hospital administrators ensure that the environment of the upcoming ICU is designed to meet the needs of patient’s relatives by addressing identified environmental concerns,like caring neglect,by providing a friendly and stress‑free environment.

(Generalized)Green's Relations of GV-Semigroups

Green's relations and generalized Green's relations play a fundamental role in the study of semigroups.GV-semigroups are the generalizations of completely regular semigroups in the range of π-regular semigroups.In this paper,Green's relations and generalized Green's relations on GV-semigroups are considered by the structure of GV-semigroups.D=j and D C D* on GV-semigroups will be proved.

SOME REMARKS ON (L)-GREEN’S RELATIONS AND STRONGLY RPP SEMIGROUPS

In order to study rpp semigroups, in particular, some special cases, several facts on （l）-Green’s relations and strongly rpp semigroups are given as some remarks.

China-US Trade Relations:Win-Win Picture Distorted

At present China-U.S.trade relations are in a state of confusion.Although both countries have gained tremendous benefits from the bilateral trade relationship,some Americans have intentionally distorted some basic facts regarding China-U.S.trade relations. Based on an analysis of some official and nonofficial research reports published in the United States,this article holds that the China-U.S.trade imbalance is the symptom of a bigger issue stemming from the contradiction between the United States as the world's sole superpower and China as an emerging power.Economic globalisation came about due to the needs of western developed countries represented by the United States to boost economic development.Only by seizing the opportunities of economic globalisation, has China gained strong economic growth. Such a development is changing the world political,economic,military and cultural landscape that have been shaped since the post-cold-war era,and has to some extent raised doubt or suspicion on the part of the United States and its western allies.This is a manifestation of how unprepared some people in the United States and other western countries are in the face of China's rapid development and rising status.So,their immediate reaction has been to seek protection for themselves,and try their utmost to prevent China's rapid growth from impacting on the international framework and their vested interests.

A Revised Interpretation of the Thermodynamic Theory Including the Einstein Mass-Energy Relation <i>E</i>= <i>mc</i>²

Thermodynamics being among the most synthetic theories of physics and the mass-energy relation E = mc2 among the most general equations of science, it is somewhat surprising that this latter is not explicitly present in the laws of thermodynamics. Coupling this observation with the conceptual difficulties often felt in learning thermodynamics leads to the idea that both situations may have the same cause. On the basis of these clues, this paper is intended to provide complementary arguments to a hypothesis already presented. It consists of showing the existence of an imperfect compatibility between the conventional formulations of the first and second laws of thermodynamics and suggesting the need of the mass-energy relation to solving the problem.

A GENERAL CONSTITUTIVE RELATION FOR FATIGUE CRACK GROWTH ANALYSIS OF METAL STRUCTURES

Crack growth rate curves are the fundamental material property for metal structures under fatigue loading. Although there are many crack growth rate curves available in the literature, few of them showed the capability to explain various special phenomena observed in tests. A modified constitutive relation recently proposed by McEvily and his co-workers showed very promising capability. This modified constitutive relation is further generalized by (1) introducing an unstable fracture condition; (2) defining a virtual strength to replace the yield stress; and (3) defining an overload and underload parameter. The performances of this general constitutive relation for fatigue crack growth is extensively studied and it is found that this general constitutive relation is able to explain various phenomena observed with particular strong capability on load sequence effect.

Africa's Perspectives on China-Africa Relations and Forum on China-Africa Cooperation(FOCAC)

China is in Africa in a vigorous way,and doing business in several countries like Sudan,Congo DRC,Angola,South Africa,and Nigeria.In the short term,the relationship may appear to be mutually beneficial.This paper seeks to address the issue of Africa's perspectives on China-Africa Relations and the FOCAC and examine the concept of strategic partnerships,determine the state of China-Africa relations,examines FOCAC and draw conclusion as well as recommendation on possible ways and issues for future engageme...

Gravitational Space-Time Quantization for Charged Wormholes and the Diophantine Uncertainty Relation

This research work proceeds from the assumption, which was still considered by Einstein, that the quantization of gravity does not require additional external procedures: quantum phenomena can be a consequence of the properties of the universal gravitational interaction, which maps any physical field upon the space-time geometry. Therefore, an attempt is made in this research work to reduce the quantization of physical fields in GRT to the space-time quantization. Three reasons for quantum phenomena are considered: Partition of space-time into a set of unconnected Novikov’s R- and T-domains impenetrable for light paths;the set is generated by the invariance of Einstein’s equations with respect to dual mappings;The existence of electric charge quanta of wormholes, which geometrically describe elementary particles in GRT. This gives rise to a discrete spectrum of their physical and geometric parameters governed by Diophantine equations. It is shown that the fundamental constants (electric charge, rest masses of an electron and a proton) are interconnected arithmetically;The existence of the so-called Diophantine catastrophe, when fluctuations in the values of physical constants tending to zero lead to fluctuations in the number of electric charges and the number of nucleons at the wormhole throats, which tend to infinity, so that the product of the increments of these numbers by the increment of physical constants forms a relation equivalent to the uncertainty relation in quantum mechanics. This suggests that space-time cannot but fluctuate, and, moreover, its fluctuations are bounded from below, so that all processes become chaotic, and the observables become averaged over this chaos.

Online dynamic measurement of saturation-capillary pressure relation in sandy medium under water level fluctuation

An online dynamic method based on electrical conductivity probe, tensiometer and datataker was presented to measure saturation-capillary pressure (S-p) relation in water-light nonaqueous phase liquid (LNAPL) two-phase sandy medium under water level fluctuation. Three-electrode electrical conductivity probe (ECP) was used to measure water saturation. Hydrophobic tensiometer was obtained by spraying waterproof material to the ceramic cup of commercially available hydrophilic tensiometer. A couple of hydrophilic tensiometer and hydrophobic tensiometer were used to measure pore water pressure and pore LNAPL pressure of the sandy medium, respectively. All the signals from ECP and tensiometer were collected by a data taker connected with a computer. The results show that this method can finish the measurement of S-p relation of a complete drainage or imbibition process in less than 60 min. It is much more timesaving compared with 10-40 d of traditional methods. Two cycles of water level fluctuation were produced, and four saturation-capillary pressure relations including two stable residual LNAPL saturations of the sandy medium were obtained during in 350 h. The results show that this method has a good durable performance and feasibility in the porous medium with complicated multiphase flow. Although further studies are needed on the signal stability and accuracy drift of the ECP, this online dynamic method can be used successfully in the rapid characterization of a LNAPL migration in porous media.

Promoting China-U.S.Arctic education cooperation:challenges,opportunities and recommendations

Arctic education refers not only to the teaching,but also to research,communication,dissemination as well as popularization of knowledge related to the Arctic.This article reviews joint efforts between Chinese and American educators and researchers to promote cooperation and understanding in Arctic education and research,and examines the facing challenges of China-U.S.Arctic education cooperation which include current political or economic tensions between the two countries,the differing perspectives and priorities on Arctic policy,the disproportion in Arctic scientific research,different research methodologies and discourse system in social science.This article also argues that there are opportunities for the two countries to cooperate in Arctic education.Common goals and interests in the Arctic,Arctic-dedicated institutions with significant Arctic research capabilities and partnerships around the world provide foundations for Arctic education cooperation.The implementation of a new science-based Arctic treaty of the Arctic Council is an opportunity for China-U.S.Arctic education cooperation.As for future cooperation,it suggests that in addition to promoting the direct bilateral cooperation,cooperation within international cooperation platforms and mechanisms,especially within the Arctic Council also needs to be further promoted.

Rayleigh reciprocity relations： Applications

Classical reciprocity relations have wide applications in acoustics, from field representation to generalized optical theorem. In this paper we introduce our recent results on the applications and generalization of classical Rayleigh reciprocity relation： higher derivative reciprocity relations as a generalization of the classical one and a theoretical proof on the Green＇s function retrieval from volume noises.

Bush' s China Policy and the Future of Sino-U.S.Relations

The past two years have witnessed great fluctuations ininternational oil prices,and diplomatic efforts,both above andunder the table,by major powers around this issue.The currenttension in the war-threatened Iraq has added more uncertainties to thefuture world oil situation.Will the world oil supply and demand change?What impact would this exert on big powers’ oil strategy choices,geopolitics as well as world economy?What should China do in such asituation?To find the answers to these questions,at the invitation of theeditor of the Contemporary International Relations,seven experts fromChina Institute of Contemporary International Relations gathered to have adiscussion in early February this year.Naturally,they have differentviews over many issues.Still,we hope our readers would find theirdiscussion interesting.Following is the list of participants.

Study on Influence of Farmers' Relational Network on Their Undertaking Process

We elaborate relevant theories of farmers' relational network,including the Differential Model of Association,the Strength of Weak Tie,Strength of Strong Tie and Favor and Face.The farmers' relational network in the Differential Model of Association can be divided into three layers:strong tie,weak tie and irrelative relationship according to Granovetter theory.These three layers have deep influence on opportunity selection during the undertaking,financing and enterprise development.With rational knowledge of these layers,farmers may exploit undertaking resources.On the basis of these,we made detailed analysis on farmers' selection of relations in the opportunity selection,financing and enterprise development stages.

Japan's Military Transformation and Sino-Japanese Military Relations

Military reform, which is led by the U. S. and sweeping its way to the rest of the world, has now become one of the hottest topics in inter- national military arena. Japan makes no exception. The reconstruction of its military forces, which is still in progress, is concentrated on the following two aspects. One is the enlargement of the functions of the Self-Defense Forces (SDF). Participation in overseas operations is in-

Seizing Opportunity to Improve China's Relations with the World

Iraq war reveals two basic features in current international situation. The first feature is disturbance. Terrorism endangering the world is a disturbance, weapons of mass destruction being proliferated over the world is a disturbance, great powers realigning is a disturbance.

Expectations for Future China-U.S. Relations

The heads of state of China and the U.S. reached a consensus in Osaka at the end of June, agreeing to restart trade negotiations on the basis of equality and mutual respect. The U.S. side stated that it would no longer impose new tariffs on Chinese imports, sending a positive sign of the U.S.-China relationship to the international community. On July 3, the Washington Post published an open letter signed by 100 people from the academic, diplomatic, military, and business circles of the U.S. to President Trump and the U.S. Congress, affirming that the consensus is the intention of the two peoples and is in line with the expectations of the international community. The decline in U.S.- China relations is not in line with U.S. and global interests, and China is not an enemy of the U.S., nor does China pose a threat to U.S. national security.