Assessment of International GNSS Service Global Ionosphere Map products over China region based on measurements from the Crustal Movement Observation Network of China

The global ionosphere maps(GIM)provided by the International GNSS Service(IGS)are extensively utilized for ionospheric morphology monitoring,scientific research,and practical application.Assessing the credibility of GIM products in data-sparse regions is of paramount importance.In this study,measurements from the Crustal Movement Observation Network of China(CMONOC)are leveraged to evaluate the suitability of IGS-GIM products over China region in 2013-2014.The indices of mean error(ME),root mean square error(RMSE),and normalized RMSE(NRMSE)are then utilized to quantify the accuracy of IGS-GIM products.Results revealed distinct local time and latitudinal dependencies in IGS-GIM errors,with substantially high errors at nighttime(NRMSE:39%)and above 40°latitude(NRMSE:49%).Seasonal differences also emerged,with larger equinoctial deviations(NRMSE:33.5%)compared with summer(20%).A preliminary analysis implied that the irregular assimilation of sparse IGS observations,compounded by China’s distinct geomagnetic topology,may manifest as error variations.These results suggest that modeling based solely on IGS-GIM observations engenders inadequate representations across China and that a thorough examination would proffer the necessary foundation for advancing regional total electron content(TEC)constructions.

The osteoclastic activity in apical distal region of molar mesial roots affects orthodontic tooth movement and root resorption in rats

The utilization of optimal orthodontic force is crucial to prevent undesirable side effects and ensure efficient tooth movement during orthodontic treatment.However,the sensitivity of existing detection techniques is not sufficient,and the criteria for evaluating optimal force have not been yet established.Here,by employing 3D finite element analysis methodology,we found that the apical distal region(A-D region)of mesial roots is particularly sensitive to orthodontic force in rats.Tartrate-resistant acidic phosphatase(TRAP)-positive osteoclasts began accumulating in the A-D region under the force of 40 grams(g),leading to alveolar bone resorption and tooth movement.When the force reached 80 g,TRAP-positive osteoclasts started appearing on the root surface in the A-D region.Additionally,micro-computed tomography revealed a significant root resorption at 80 g.Notably,the A-D region was identified as a major contributor to whole root resorption.It was determined that 40 g is the minimum effective force for tooth movement with minimal side effects according to the analysis of tooth movement,inclination,and hyalinization.These findings suggest that the A-D region with its changes on the root surface is an important consideration and sensitive indicator when evaluating orthodontic forces for a rat model.Collectively,our investigations into this region would aid in offering valuable implications for preventing and minimizing root resorption during patients’orthodontic treatment.

Towards precision 24-hour movement behavior recommendations—The next new paradigm?

1.Background The importance of physical activity(PA)for health is unequivocal.^(1)Accordingly,population-based recommendations for exercise,and more recently public health guidelines for PA,have been developed and released by authoritative groups for many decades.^(2)Such guidelines emerged with leadership from the exercise physiology discipline and were rooted in,and loyal to,the importance of moderate-to-vigorous intensity PA(MVPA)or exercise.

Modifying the progression of Parkinson's disease through movement interventions:multimodal quantification of underlying mechanisms

Introduction:Parkinson’s disease(PD)is the most common neurodegenerative movement disorder.The pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structu re and function of distributed brain networks.Togethe r,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).

Dual roles of the amygdala-hippocampus circuit in the regulation of rapid eye movement sleep and depression symptoms by repetitive transcranial magnetic stimulation in patients with insomnia

To the editor:It is commonly reported that people with insomnia often experience comorbid emotional disorders,such as mood and anxiety disorders.12 A study found that fragmented rapid eye movement(REM)sleep in individuals with insomnia is associated with higher Beck Depression Inventory(BDI)scores.3 REM sleep architecture disruption is a typical symptom of insomnia.

Engineering The Neck Hinge Reshapes The Processive Movement of Kinesin-3

Objective In kinesin-3,the neck coil correlates with the following segments to form an extended neck that contains a characteristic hinge diverse from a proline in KIF13B to a long flexible linker in KIF1A.The function of this neck hinge for controlling processive movement,however,remains unclear.Methods We made a series of modifications to the neck hinges of KIF13B and KIF1A and tested their movement using a single-molecule motility assay.Results In KIF13B,the insertion of flexible residues before or after the proline differentially impacts the processivity or velocity,while the removal of this proline increases the both.In KIF1A,the deletion of entire flexible neck hinge merely enhances the processivity.The engineering of these hinge-truncated necks of kinesin-3 into kinesin-1 similarly boosts the processive movement of kinesin-1.Conclusion The neck hinge in kinesin-3 controls its processive movement and proper modifications tune the motor motility,which provides a novel strategy to reshape the processive movement of kinesin motors.

Present-day movement characteristics of the Qinghai Nanshan fault and its surrounding area from GPS observation

The Qinghai Nanshan fault is a larger fault in the Northeastern Xizang Plateau.In previous studies,its movement characteristics are mainly investigated with geological and seismic observations,and the tectonic transformation role of the fault on its east is not yet clear.This study uses data fusion to obtain denser GPS observations near the Qinghai Nanshan fault.Based on tectonic characteristics,we establish a block model to investigate the fault slip rate,locking degree,and slip deficit.The results show that the Qinghai Nanshan fault slip rate is characterized by sinistral and convergent movement.Both the sinistral and convergent rates display a decreasing trend from west to east.The locking degree and slip deficit are higher in the western segment(with an average of about 0.74 and 1.1 mm/a)and lower in the eastern segment.Then,we construct a strain rate field using GPS observations to analyze the regional strain characteristics.The results indicate that along the fault,the western segment shows a larger shear strain rate and negative dilation rate.Regional earthquake records show that the frequency of earthquakes is lower near the fault.The joint results suggest that the western segment may have a higher earthquake risk.In addition,the insignificant fault slip rate in the eastern segment may indicate that it does not participate in the tectonic transformation among the Riyueshan,Lajishan,and West Qinling faults.

Experimental study on the movement of oil spill under freeze-thaw action

Oil leakages cause environmental pollution,economic losses,and even engineering safety accidents.In cold regions,researchers urgently investigate the movement of oil spill in soils exposed to freeze-thaw cycles.In this study,a series of laboratory model experiments were carried out on the migration of oil leakage under freeze-thaw action,and the distributions of the soil temperature,unfrozen water content,and displacement were analyzed.The results showed that under freeze-thaw action,liquid water in soils migrated to the freezing front and accumulated.After the pipe cracked,oil pollutants first gathered at one side of the leak hole,and then moved around.The pipe wall temperature affected the soil temperature field,and the thermal influence range below and transverse the pipe wall(35–40 cm)was larger than that above the pipe wall(8 cm)owing to the soil surface temperature.The leaked oil's temperature would make the temperature of the surrounding soil rise.Oil would inhibit the cooling of the soils.Besides,oil migration was significantly affected by the gravity and water flow patterns.The freeze-thaw action would affect the migration of the oil,which was mainly manifested as inhibiting the diffusion and movement of oil when soils were frozen.Unfrozen water transport caused by freeze-thaw cycles would also inhibit oil migration.The research results would provide a scientific reference for understanding the relationship between the movement of oil pollutants,water,and soil temperature,and for establishing a waterheat-mass transport model in frozen soils.

On the Cooperation Between China and the Non-Aligned Movement in the Field of the Right to Development and its Prospects

China and the Non-Aligned Movement share the same goals,a common code of conduct,and similar ideas in protecting the right to development,and the two have a solid foundation for cooper-ation.Both emphasize that the right to development is a basic human right,strive to elevate the right to development to a mainstream hu-man right,and jointly advocate placing the right to development at the center of the agenda.They work together to enhance the strategic sta-tus of the right to development.Both of them have participated in the formulation of the Declaration on the Right to Development,and col-laborated to improve the Declaration.They have also jointly proposed the resolution on the right to development,and supported the drafting of the Convention on the Right to Development to advance the codifi-cation of the right to development.Both of them uphold South-South cooperation and promote North-South dialogue and cooperation.They have established a support mechanism to promote international cooperation on the right to development in a coordinated manner.The cooperation between China and the Non-Aligned Movement in pro-tecting the right to development has broken the past Western-centered paradigm of human rights development,broadened the international perspective of the human rights cause,and played a crucial role in the formation of international human rights norms.In the future,oppor-tunities and challenges coexist for cooperation between the two sides,with promising prospects.China’s cooperation with the Non-Aligned Movement in the protection of the right to development has accumulat-ed valuable and inspirational experiences for the human rights cause of developing countries and the building of the international human rights system.。

Gender equality policy of the Olympic Movement in Chinese sport governing bodies:the case of elite volleyball

Objectives:This research based on the theoretical framework of globalisation focuses on the development of gender equality policy in the Olympic Movement and the implementation of IOC’s gender equality policy in the context of Chinese elite volleyball.Methods:In addition to documentary analysis,17 semistructured interviews were conducted with key insiders within Chinese elite volleyball system to provide a comprehensive understanding of the IOC’s gender equality policy implementation.The analysisinvolved perspectives of athletes’participation,coaching positions,and leadership roles according to three main elements of the IOC’s gender equality policy.Results:Thefindings demonstrated that the responses of Chinese elite volleyball to IOC’s gender equality policy are participative,conflictual,and passive in terms of the gender balance of athletes’participation,coaches’positions,and the representation of leadership roles respectively.Conclusions:IOC recommended subordinated stakeholders including NOCs to implement gender equality policy.The attitude of Chinese elite volleyball governing body towards gender equality is generally positive.However,IOC’s gender equality policy is not consistently transferred at national level.Policy might be implemented with symbolic measure in China without monitoring system.Referees should be included in policy contents in addition to athletes,coaches and leaders.In addition,since IOC’s gender equality policy and statistics have been keeping updated,further results with respect to the case of volleyballshould be demonstrated in future research.

Is It about a Bicycle? A Posthumanist Perspective on the Role of Women’s Bicycles in WWII Resistance Movements

Drawing upon Donna Haraway’s cyborg theory,this paper argues that the bicycle can be conceived as a cyborg extension of body and identity which transcended its mechanical essence to become an integral co-partner for women involved in resistance activities in WWII.More specifically,the study explores how women used cycling during World War Ⅱ not only for mobility but as a profound expression of courage,endurance and solidarity which enabled them to overcome physical and symbolic barriers under totalitarian regimes.The bicycle emerges not only as a central co-agent but also actively co-creates the situations in which it emerges as a transformative force.Cycling acted as a catalyst for personal and collective empowerment,fostering new subjectivities while transcending physical and social limitations.This study sparks multidimensional discourse on how technological tools can co-create our societies and identities,offering insights into how bicycles can drive socio-political change,promote emancipation and foster inclusivity.

“Eternal Motion” as a “Form of Movement of a Special Nature” and the Main Condition for the Creation of the Universe

The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-sufficiency, and by “Special Nature”, gravitational and two other properties of matter, “tied” to the “Eternal Movement” and completely dependent on it. Carriers of key properties of a “Special Nature” have been established: “0”-DE particles and “3”-DM particles (UDM). The unity of their inherent “motionally-gravitational” properties and the peculiarity of the relationship between “motion” and “gravity” are revealed: the higher the intensity of “Eternal Motion”, the stronger the gravitational properties of matter are manifested (and vice versa). The relationship of “time” with the “vibration frequency” and the “mass” of photons with the “degree of bonding and deformation properties of the field” is shown. The maximum level of gravity has been determined, which allows Nature to successfully create the Universe: such a landmark is the proximity to the property of the Primary Source—the “pure graviton” of the OSP space, the most powerful “motionally-gravitational” particle of the Universe. The reasons for the emergence of such an identity of the gravitational properties of particles with the indicators of a “pure graviton” are established: for “0”-DE particles, this is the acquisition of the function of “freedom of movement”;for “3”-DM particles (UDM), the creation of a special structure—a “double field” (“Main” and “Small”). The presence in the “double field” of specific “tools” for the creation of the worlds of the Universe—gravitational “waves” gives rise to impulses (shocks) of varying intensity and shape. A list of functions performed by “waves” in the “Main” and “Small” fields has been compiled. The specific conditions for the formation of “UDM Streams”, their transformation into a “Vortex” and, under the influence of a powerful Initial Impulse (push), sending them to the “place” of the creation of galaxies, are shown. It is suggested that there is a “Cycle of Matter in Nature” in the closed structure of our Universe due to the “work” of “waves” and the functioning of special “factories” in the form of exotic space objects—Black holes.

Hua Tuo’s Wu Qin Xi (Five Animal Frolics) Movements and the Logic behind It

The key proposition of this hypothesis is logic behind the order of movements of Hua Tuo’s qigong Wu Qin Xi(Five animal frolics).To date,there were many discussions about connection of the movements of Wu Qin Xi with existing TCM theories and why Hua Tuo made it in that particular way.Some experts are saying that there is no connection but if all stories of Hua Tuo’s abilities and knowledge were half-truth,he wouldn’t let even the order of movements of qigong that he created be just a random order.Hypothesis is exploring different views on Taiji movement direction,Wu Xing and connection between animals in Wu Qin Xi,Lo Shu square and Sun wheel and proposing possible solution to the question“Why Hua Tuo made such order of animals in Wu Qin Xi?”by analyzing and and cross referencing the common ground between theories and bridging the gap the we were left without any written explanation from the master itself.Further progress and confirmation of this hypothesis requires deeper research and cooperation between Qigong expert historians.

A Study on the Law of Birth and Formation of Yang-Deficiency Constitution Based on the Theory of Five Movement and Six Qi

Objective:To explore the law of birth and yang deficiency constitution based on the theory of five movements and six qi,as well as to provide a new way to better realize the prevention of yang deficiency constitution.Methods:The data of TCM quality table and luck data were collected via questionnaires.According to the data of from the TCM quality table,the respondents were divided into yang deficiency constitution group and non-yang deficiency group.According to the luck data,the distributions of gestational age were compared between the two groups.Results:A total of 175 questionnaires were collected,of which 89 were non-yang deficiency constitution and 86 were yang deficiency constitution.The proportion of Ding year(15.1%)in the yang deficiency group was significantly higher than that in non-yang deficiency group(5.6%),in which the difference was statistically significant(P<0.05).Conclusion:The possibility of yang deficiency constitution is higher.

Photosynthetic Gas Exchange and Leaflet Movement of Robinia pseudoacacia in Relation to Changing Light Environments

On the sunny days, there were little diurnal changes in both azimuth and directional angle for either sun_ or shade_leaflet. However, there existed a significant diurnal change in midrib angle that reflected movements regarding evasion of light stress around noon hours. On the cloudy day, a very little diurnal difference was found in azimuth, directional and midrib angle. It is suggested that changing light environment is the main factor for inducing leaflet movement of Robinia pseudoacacia , and the rhythmical movement does not attribute to the leaflet movement. Leaf orientation control test showed that the photosynthetic rate ( Pn ), stomatal conductance ( g s ) and transpiration ( Tr ) of the artificial fixed_leaflets were significantly lower than that of control_leaflets. And the leaf temperature ( Tl ) of the fixed leaflets significantly exceeded that of control_leaflets, which may attribute to the significant difference of light interception between the fixed and control_leaflets. The light_dependent leaflet movement is the morphological adjustment of maintaining optimal physiological status.

Existence of Extracellular Calmodulin in the Lower Epidermis of the Leaves of Vicia faba and Its Role in Regulating Stomatal Movements

As a possible peptide primary messenger, extracellular calmodulin (CaM) may regulate processes such as cell proliferation, pollen germination and expression of some genes. Stomata open or close quickly in response to environmental stimuli. CaM was found to be extracellular both in guard cells of broad bean leaves and in epidermal cells by immuno-electron microscopy and immuno-fluorescence microscopy techniques. Exogenous purified CaM enhanced stomatal closure and inhibited stomatal opening with an optimal concentration of 10(-8) mol/L; CaM antagonist W7-agarose and anti-CaM serum, which were membrane-impermeable macromolecules, inhibited stomatal closure and promoted stomatal opening. All these data showed that endogenous extracellular CaM. of guard cells did promote stomatal closure and inhibit stomatal opening, and could he active only outside the cells. Therefore under natural conditions, the endogenous extracellular CaM of guard cells might regulate stomatal movements as a primary messenger together with other signal molecules, and might be an important linkage between environmental stimuli and cell responses.

Research on the influences of motion characteristics of jetting projectile charge under water

Shaped charge warhead is important for enhancing the damage performance of underwater weapons.This paper used finite element analysis software and based on JPC water penetration experiments to examine the influence of liner parameters(wall thickness,material),charge aspect ratio,and stand-off distance on the movement characteristics of JPC in water.The findings reveal that the head diameter of the JPC increases and experiences significant erosion after entering the water,the effective length of the JPC in water undergoes two distinct phases:a growth phase and a decrease phase,with the velocity of the JPC decaying exponentially.Increasing the liner thickness,stand-off distance and the charge aspect ratio can improve the erosion resistance and the velocity retention capacity of the JPC.The optimal ranges for liner thickness and stand-off distance are 0.0363D_(k) to 0.0545D_(k)(D_(k) is the charge diameter),the stand-off distance should be within 1.0D_(k).After the charge aspect ratio higher than 1.25,the charge structure exerts minimal influence the movement characteristics of the JPC in water.Material density plays a crucial role in the velocity decay pattern of the JPC during penetration.JPC with higher densities exhibit superior velocity retention capabilities in water,with the velocity decay pattern converging if the densities are similar.Consequently,copper,tantalum and tungsten liners are deemed appropriate for underwater shaped charge warhead.Finally,the results will provide an important reference for the design of underwater shaped charge warhead.

Genetic pathways in cerebral palsy:a review of the implications for precision diagnosis and understanding disease mechanisms

Ce rebral palsy is a diagnostic term utilized to describe a group of permanent disorders affecting movement and posture.Patients with cerebral palsy are often only capable of limited activity,resulting from non-progressive disturbances in the fetal or neonatal brain.These disturbances severely impact the child’s daily life and impose a substantial economic burden on the family.Although cerebral palsy encompasses various brain injuries leading to similar clinical outcomes,the unde rstanding of its etiological pathways remains incomplete owing to its complexity and heterogeneity.This review aims to summarize the current knowledge on the genetic factors influencing cerebral palsy development.It is now widely acknowledged that genetic mutations and alterations play a pivotal role in cerebral palsy development,which can be further influenced by environmental fa ctors.Des pite continuous research endeavors,the underlying fa ctors contributing to cerebral palsy remain are still elusive.However,significant progress has been made in genetic research that has markedly enhanced our comprehension of the genetic factors underlying cerebral palsy development.Moreove r,these genetic factors have been categorized based on the identified gene mutations in patients through clinical genotyping,including thrombosis,angiogenesis,mitochondrial and oxidative phosphorylation function,neuronal migration,and cellular autophagy.Furthermore,exploring targeted genotypes holds potential for precision treatment.In conclusion,advancements in genetic research have substantially improved our understanding of the genetic causes underlying cerebral palsy.These breakthroughs have the potential to pave the way for new treatments and therapies,consequently shaping the future of cerebral palsy research and its clinical management.The investigation of cerebral palsy genetics holds the potential to significantly advance treatments and management strategies.By elucidating the underlying cellular mechanisms,we can develop to rgeted interventions to optimize outcomes.A continued collaboration between researchers and clinicians is imperative to comprehensively unravel the intricate genetic etiology of cerebral palsy.

Three-dimensional crustal movement and the activities of earthquakes,volcanoes and faults in Hainan Island,China

Hainan Island is a seismic active region, where Qiongshan M7.5 earthquake occurred in 1605 and several seismic belts appeared in recent years, especially the NS trending seismic belt （NSB） located in the northeast part of the island. Here is also a magmatic active region. The lava from about 100 volcanoes covered more than 4000 km^2. The latest eruptions occurred on Ma＇anling-Lei Huling volcanoes within 10,000 years. The neotectonic movement has been determined by geological method in the island and its adjacent areas. In the paper, the present-day 3D crustal movement is obtained by using Global Positioning System （GPS） data observed from 2009 to 2014 and leveling observations measured in 1970s and 1990s respectively. The results show the horizontal movement is mainly along SEE direction relative to the Eurasian Plate. The velocities are between 4.01 and 6.70 mm/a. The tension rate near the NSB is less than I mm/a. The vertical movement shows the island uplifts as a whole with respect to the reference benchmark Xiuyinggang. The average uplifting rate is 2.4 mm/a. The rates are 2-3 mm/a in the northwest and 3-5mm/a in the northwest. It shows the deformation pattern of the southwest island is upward relative to the northeast, which is different from the result inferred from the coastal change and GPS. Haikou and its adjacent region present a subsidence in a long time. The southern part of the middle segment of the Wangwu-Wenjiao fault uplifts relative to the northern. Meanwhile, the western part uplifts relative to the eastern NSB. The vertical crustal motion and the two normal faults nearly correspond to the terrain. The NSB is located along the Puqiangang-Dazhibo fault, which is assessed as a segmented fault with a dip of 80°-90° and party exposed. The 3D deformations and other studies reveal the present activities of earthquakes, volcanoes and the faults. The small earthquakes will still occur in the NS belt and the volcanoes are not active now.

Tectonic Taphrogenesis and Paleoseismic Records from the Yishu Fault Zone in the Initial Stage of the Caledonian Movement

The Yishu fault zone （mid-segment of the Tanlu fault zone） was formed in the Presinian. Periodic tectonic activities and strong seismic events have occurred along the fault zone. During the initial stage of the Caledonian Movement, with the proceeding of the marine transgression from the Yishu paleo-channel to the western Shandong, uneven thick sediments, composed mainly of sand, mud and carbonates of littoral, lagoon, and neritic facies, were deposited in the Yishu fault zone and western Shandong, and constructed the bottom part of the Lower Cambrian consisting of the Liguan and Zhushadong formations. Through field observations and the lab-examinations, various paleoseismic records have been discovered in the Liguan Formation and the Zhushadong Formations of the Yishu fault zone and its vicinity, including some layers with syn-sedimentary deformation structures that were triggered by strong earthquakes （i.e. seismite, seismo-olistostrome, and seismo-turbidite）. Paleoseismic records developed in the Zhushadong Formation are mainly seismites with soft-sediment deformation structures, such as liquefied diapir, small liquefied-carbonate lime-mud volcano, liquefied vein, liquefied breccia, convolute deformation （seismic fold）, graded fault, soft siliceous vein, and deformation stromatolite, as well as seismites with brittle deformation structures of semiconsolidated sediments. Paleoseismic records preserved in the Liguan Formation are not only seismo-olistostrome with a slump fold, load structure, and ball-and-pillows, but also seismo-turbidite with convolution bedding, graded bedding and wavy-bedding. However, in the western Shandong area, the closer to the Yishu fault zone, the greater the thickness of the Liguan Formation and the Zhushadong Formation, the greater the number and type of layers with paleoseismic records, and the higher the earthquake intensity reflected by associations of seismic records. This evidence indicates that tectonic taphrogenesis accompanied by strong earthquake events occurred in the Yishu fault zone during the initial stage of the Caledonian Movement, which embodied the break-up of the Sino-Korean Plate along the Paleo-Tanlu fault zone at that time.