Association rule learning(ARL)is a widely used technique for discovering relationships within datasets.However,it often generates excessive irrelevant or ambiguous rules.Therefore,post-processing is crucial not only f...Association rule learning(ARL)is a widely used technique for discovering relationships within datasets.However,it often generates excessive irrelevant or ambiguous rules.Therefore,post-processing is crucial not only for removing irrelevant or redundant rules but also for uncovering hidden associations that impact other factors.Recently,several post-processing methods have been proposed,each with its own strengths and weaknesses.In this paper,we propose THAPE(Tunable Hybrid Associative Predictive Engine),which combines descriptive and predictive techniques.By leveraging both techniques,our aim is to enhance the quality of analyzing generated rules.This includes removing irrelevant or redundant rules,uncovering interesting and useful rules,exploring hidden association rules that may affect other factors,and providing backtracking ability for a given product.The proposed approach offers a tailored method that suits specific goals for retailers,enabling them to gain a better understanding of customer behavior based on factual transactions in the target market.We applied THAPE to a real dataset as a case study in this paper to demonstrate its effectiveness.Through this application,we successfully mined a concise set of highly interesting and useful association rules.Out of the 11,265 rules generated,we identified 125 rules that are particularly relevant to the business context.These identified rules significantly improve the interpretability and usefulness of association rules for decision-making purposes.展开更多
This paper reviewed the literature on medication rule of pulmonary nodules in recent years. It is found that contemporary doctors pay more attention to regulating Qi, clearing heat and detoxifying, eliminating phlegm,...This paper reviewed the literature on medication rule of pulmonary nodules in recent years. It is found that contemporary doctors pay more attention to regulating Qi, clearing heat and detoxifying, eliminating phlegm, dissolving phlegm and dissipating masses. They use mild drugs, cold and warm treatments in parallel, combining the tastes of pungent, bitterness, and sweetness at the same time. The treatment focuses on the five viscera with emphasis on the lung meridian while also considering the spleen and stomach functions as well as soothing liver stagnation. This information aims to provide some reference for clinical treatment of pulmonary nodules.展开更多
Media convergence works by processing information from different modalities and applying them to different domains.It is difficult for the conventional knowledge graph to utilise multi-media features because the intro...Media convergence works by processing information from different modalities and applying them to different domains.It is difficult for the conventional knowledge graph to utilise multi-media features because the introduction of a large amount of information from other modalities reduces the effectiveness of representation learning and makes knowledge graph inference less effective.To address the issue,an inference method based on Media Convergence and Rule-guided Joint Inference model(MCRJI)has been pro-posed.The authors not only converge multi-media features of entities but also introduce logic rules to improve the accuracy and interpretability of link prediction.First,a multi-headed self-attention approach is used to obtain the attention of different media features of entities during semantic synthesis.Second,logic rules of different lengths are mined from knowledge graph to learn new entity representations.Finally,knowledge graph inference is performed based on representing entities that converge multi-media features.Numerous experimental results show that MCRJI outperforms other advanced baselines in using multi-media features and knowledge graph inference,demonstrating that MCRJI provides an excellent approach for knowledge graph inference with converged multi-media features.展开更多
The objective principles of shiology are mainly reflected in three fields as food acquisition, eaters' health and shiance order. Most of the objective principles in the field of food acquisition have been revealed...The objective principles of shiology are mainly reflected in three fields as food acquisition, eaters' health and shiance order. Most of the objective principles in the field of food acquisition have been revealed by agronomy and foodstuff science. This research mainly focuses on 10 principles in the field of eaters' health and shiance order and in addition, there are also five lemmas that extend from the above principles. The 10 principles are the core theory of the shiology knowledge system, which play an important role in the objective principles revealed by human beings and constitute one of the basic principles of human civilization. Compared with the scientific principles of mathematics, physics, chemistry and economics, the principles of shiology have three characteristics as popularity, practicability and survivability. The principles of shiology in the field of eaters' health are all around us, and everyone can understand and master them. Using the principles of shiology can improve the healthy life span of 8 billion people. The principles of shiology in the field of shiance order is an important tool of social governance, which can reduce human social conflicts, reduce social involution, improve overall efficiency of social operation, and maintain the sustainable development of human beings.展开更多
Breast cancer remains a significant global health challenge, necessitating effective early detection and prognosis to enhance patient outcomes. Current diagnostic methods, including mammography and MRI, suffer from li...Breast cancer remains a significant global health challenge, necessitating effective early detection and prognosis to enhance patient outcomes. Current diagnostic methods, including mammography and MRI, suffer from limitations such as uncertainty and imprecise data, leading to late-stage diagnoses. To address this, various expert systems have been developed, but many rely on type-1 fuzzy logic and lack mobile-based applications for data collection and feedback to healthcare practitioners. This research investigates the development of an Enhanced Mobile-based Fuzzy Expert system (EMFES) for breast cancer pre-growth prognosis. The study explores the use of type-2 fuzzy logic to enhance accuracy and model uncertainty effectively. Additionally, it evaluates the advantages of employing the python programming language over java for implementation and considers specific risk factors for data collection. The research aims to dynamically generate fuzzy rules, adapting to evolving breast cancer research and patient data. Key research questions focus on the comparative effectiveness of type-2 fuzzy logic, the handling of uncertainty and imprecise data, the integration of mobile-based features, the choice of programming language, and the creation of dynamic fuzzy rules. Furthermore, the study examines the differences between the Mamdani Inference System and the Sugeno Fuzzy Inference method and explores challenges and opportunities in deploying the EMFES on mobile devices. The research identifies a critical gap in existing breast cancer diagnostic systems, emphasizing the need for a comprehensive, mobile-enabled, and adaptable solution by developing an EMFES that leverages Type-2 fuzzy logic, the Sugeno Inference Algorithm, Python Programming, and dynamic fuzzy rule generation. This study seeks to enhance early breast cancer detection and ultimately reduce breast cancer-related mortality.展开更多
Objective:To apply and verify the application of intelligent audit rules for urine analysis by Cui et al.Method:A total of 1139 urine samples of hospitalized patients in Tai’an Central Hospital from September 2021 to...Objective:To apply and verify the application of intelligent audit rules for urine analysis by Cui et al.Method:A total of 1139 urine samples of hospitalized patients in Tai’an Central Hospital from September 2021 to November 2021 were randomly selected,and all samples were manually microscopic examined after the detection of the UN9000 urine analysis line.The intelligent audit rules(including the microscopic review rules and manual verification rules)were validated based on the manual microscopic examination and manual audit,and the rules were adjusted to apply to our laboratory.The laboratory turnaround time(TAT)before and after the application of intelligent audit rules was compared.Result:The microscopic review rate of intelligent rules was 25.63%(292/1139),the true positive rate,false positive rate,true negative rate,and false negative rate were 27.66%(315/1139),6.49%(74/1139),62.34%(710/1139)and 3.51%(40/1139),respectively.The approval consistency rate of manual verification rules was 84.92%(727/856),the approval inconsistency rate was 0%(0/856),the interception consistency rate was 12.61%(108/856),and the interception inconsistency rate was 0%(0/856).Conclusion:The intelligence audit rules for urine analysis by Cui et al.have good clinical applicability in our laboratory.展开更多
Cropland elevation uplift(CLEU) has recently become a new challenge for agricultural modernization,food security,and sustainable cropland use in China.Uncovering the rules of CLEU is of great theoretical and practical...Cropland elevation uplift(CLEU) has recently become a new challenge for agricultural modernization,food security,and sustainable cropland use in China.Uncovering the rules of CLEU is of great theoretical and practical significance for China’s sustainable agricultural development and rural revitalization strategy.However,existing studies lack in-depth disclosure of multi-scale CLEU evolution rules,making it difficult to support the formulation of specific cropland protection policies.We analyzed the spatio-temporal evolution and multiscale CLEU in China from 1980 to 2020 using the Lorenz curve,gravity center model,hotspot analysis,and cropland elevation spectrum.The results indicated that the center of gravity of cropland moved to the northeast from 1980 to 2000 and then shifted to the northwest.The spatial distribution of cropland became increasingly imbalanced from 1980 to 2000.The change hotspots clustered in the northwest and the northeast,whereas cold-spots were mainly in southeastern China.The average elevation of cropland increased by 17.38 m,and the elevation uplift rule in different regions differed evidently across scales.From 1980 to 2000,all provinces except Xinjiang,Inner Mongolia,Gansu,and Yunnan exhibited CLEU,with Qinghai,Tibet,Beijing,and Guangdong showing the most noticeable uplifting.The CLEU can alleviate the shortage of cropland to some extent.However,without a planning constraint,the CLEU will lead to the increase of ecological risk and food security risk.展开更多
Fault diagnosis plays an irreplaceable role in the normal operation of equipment.A fault diagnosis model is often required to be interpretable for increasing the trust between humans and the model.Due to the understan...Fault diagnosis plays an irreplaceable role in the normal operation of equipment.A fault diagnosis model is often required to be interpretable for increasing the trust between humans and the model.Due to the understandable knowledge expression and transparent reasoning process,the belief rule base(BRB)has extensive applications as an interpretable expert system in fault diagnosis.Optimization is an effective means to weaken the subjectivity of experts in BRB,where the interpretability of BRB may be weakened.Hence,to obtain a credible result,the weakening factors of interpretability in the BRB-based fault diagnosis model are firstly analyzed,which are manifested in deviation from the initial judgement of experts and over-optimization of parameters.For these two factors,three indexes are proposed,namely the consistency index of rules,consistency index of the rule base and over-optimization index,tomeasure the interpretability of the optimizedmodel.Considering both the accuracy and interpretability of amodel,an improved coordinate ascent(I-CA)algorithmis proposed to fine-tune the parameters of the fault diagnosis model based on BRB.In I-CA,the algorithm combined with the advance and retreat method and the golden section method is employed to be one-dimensional search algorithm.Furthermore,the random optimization sequence and adaptive step size are proposed to improve the accuracy of the model.Finally,a case study of fault diagnosis in aerospace relays based on BRB is carried out to verify the effectiveness of the proposed method.展开更多
The hot-spring snakes,Thermophis, were previously known only from the Tibet Autonomous Region and Western Sichuan, China. During the past two years, three adult hot-spring snakes (2 females, 1 male) were sampled in ...The hot-spring snakes,Thermophis, were previously known only from the Tibet Autonomous Region and Western Sichuan, China. During the past two years, three adult hot-spring snakes (2 females, 1 male) were sampled in Shangri-La, northern Yunnan, China, thus expanding their known distribution region towards the southeast. This site is the southeastern-most corner of the Tibetan Plateau and the southernmost tip of the Hengduan Mountains (Mts.). Phylogenetic analysis of mitochondrial (mt) and nuclear (n) DNA segments suggested that the three specimens belong to the genus ofThermophis. Morphologically, the new species is more similar toT. zhaoermii. However, it is distinguished fromT.zhaoermiiin the number of maxillary teeth (15), distance between the two eyes/head width, rostral width/height, mental width/height, in one character limited to female: head width/length, and in four characters restricted to male: occurrence of the reduction from 10 to 8 (8 to 6, 6 to 4) scales in each dorsal row on the tail. There are differences in morphology, genetics (mtDNA, nDNA), and geography between the putative new species andT.zhaoermii,the new species meets our proposed eclectic and feasible "four-differences" rule.展开更多
Ions or molecules are said to be isoelectronic if they are composed of different elements but have the same number of electrons, the same number of covalent bonds and the same structure. This criterion is unfortunatel...Ions or molecules are said to be isoelectronic if they are composed of different elements but have the same number of electrons, the same number of covalent bonds and the same structure. This criterion is unfortunately not sufficient to ensure that a chemical structure is a valid chemical compound. In a previous article, a procedure has been described to draw 2D valid structural formulas: the even-odd rule. This rule has been applied first to single-bonded molecules then to single-charged single-bonded ions. It covers hypovalent, hypervalent or classic Lewis’ octet compounds. The funding principle of the even-odd rule is that each atom of the compound possesses an outer-shell filled only with pairs of electrons. The application of this rule guarantees validity of any single-covalent-bond chemical structure. In the present paper, this even-odd rule and its electron-pair criterion are checked for coherence with an effective-valence isoelectronic rule using numerous known compounds having single-covalent-bond connections. The test addresses Lewis’ octet ions or molecules as well as hypovalent and hypervalent compounds. The article concludes that the even-odd rule and the effective-valence isoelectronicity rule are coherent for known single-covalent-bond chemical compounds.展开更多
The recently introduced even-odd rule has been shown to successfully represent chemical structures of ions and molecules. While comparing available drawings in the scientific literature with the list of compounds pred...The recently introduced even-odd rule has been shown to successfully represent chemical structures of ions and molecules. While comparing available drawings in the scientific literature with the list of compounds predicted by the even-odd rule, it became however obvious that existing compounds are fewer than expected. Several predicted compounds involving many covalent bonds have apparently never been experimentally observed. Neutral oxygen for instance is expected to have 6 valence electrons, whereas oxygen can only build a maximum of two bonds, as in water. This specificity is observed for elements in the top-right corner of the periodic table. For compounds to contain only single covalent bonds, and thus follow the even-odd rule, further explanations are necessary. The present paper proposes that those specific elements experience a transfer of electrons from the valence shell into the inner shell, making them unavailable for further bonding. These elements will be described as organic, hereby providing a clear and hopefully unifying definition of the term. In opposition, inorganic elements have a constant inner shell no matter their electrical state or the number of bonds they maintain. More than 70 compounds involving 11 elements of the main group are studied, revealing a progression from fully inorganic elements at the left of the periodic table to fully organic elements. The transition between inorganic or organic elements is made of few elements that take an organic form when negatively charged;they are labelled semi-organic. The article concludes that the fully organic elements of the main group are Oxygen and Fluorine, whereas semi-organic elements are more numerous: C, N, S, Cl, Se, Br and I. Thus, the even-odd rule becomes fully compatible with scientific knowledge of compounds in liquid or gaseous phase.展开更多
Following the introduction of the new even-odd and isoelectronic rules and definitions affecting the understanding of electronic structure and bonds, the author has thought necessary to summarize understandings in the...Following the introduction of the new even-odd and isoelectronic rules and definitions affecting the understanding of electronic structure and bonds, the author has thought necessary to summarize understandings in the form of a table. The classical periodic table, a simple tool used by generations of physicists, is here extended to become a useful tool aimed specifically at chemists. In chemistry, position and number of covalent bonds of each atom are needed, as well as the exact location of charges. The table gives the number of possible bonds for each element and reveals how it is affected by charges. Additionally, the specific table indicates for each atom its isoelectronic elements and highlights the distinction between organic and inorganic elements. Discussion is led on the first two rows of the table by successfully comparing its statement with more than 50 well-known liquid and gaseous compounds.展开更多
The basic principles of IF/THEN rules in rough set theory are analyzed first, and then the automatic process of knowledge acquisition is given. The numerical data is qualitatively processed by the classification of me...The basic principles of IF/THEN rules in rough set theory are analyzed first, and then the automatic process of knowledge acquisition is given. The numerical data is qualitatively processed by the classification of membership functions and membership degrees to get the normative decision table. The regular method of relations and the reduction algorithm of attributes are studied. The reduced relations are presented by the multi-representvalue method and its algorithm is offered. The whole knowledge acquisition process has high degree of automation and the extracted knowledge is true and reliable.展开更多
Themulti-skill resource-constrained project scheduling problem(MS-RCPSP)is a significantmanagement science problem that extends from the resource-constrained project scheduling problem(RCPSP)and is integrated with a r...Themulti-skill resource-constrained project scheduling problem(MS-RCPSP)is a significantmanagement science problem that extends from the resource-constrained project scheduling problem(RCPSP)and is integrated with a real project and production environment.To solve MS-RCPSP,it is an efficient method to use dispatching rules combined with a parallel scheduling mechanism to generate a scheduling scheme.This paper proposes an improved gene expression programming(IGEP)approach to explore newly dispatching rules that can broadly solve MS-RCPSP.A new backward traversal decoding mechanism,and several neighborhood operators are applied in IGEP.The backward traversal decoding mechanism dramatically reduces the space complexity in the decoding process,and improves the algorithm’s performance.Several neighborhood operators improve the exploration of the potential search space.The experiment takes the intelligent multi-objective project scheduling environment(iMOPSE)benchmark dataset as the training set and testing set of IGEP.Ten newly dispatching rules are discovered and extracted by IGEP,and eight out of ten are superior to other typical dispatching rules.展开更多
In this paper,we define the curve rλ=r+λd at a constant distance from the edge of regression on a curve r(s)with arc length parameter s in Galilean 3-space.Here,d is a non-isotropic or isotropic vector defined as a ...In this paper,we define the curve rλ=r+λd at a constant distance from the edge of regression on a curve r(s)with arc length parameter s in Galilean 3-space.Here,d is a non-isotropic or isotropic vector defined as a vector tightly fastened to Frenet trihedron of the curve r(s)in 3-dimensional Galilean space.We build the Frenet frame{Tλ,Nλ,Bλ}of the constructed curve rλwith respect to two types of the vector d and we indicate the properties related to the curvatures of the curve rλ.Also,for the curve rλ,we give the conditions to be a circular helix.Furthermore,we discuss ruled surfaces of type A generated via the curve rλand the vector D which is defined as tangent of the curve rλin 3-dimensional Galilean space.The constructed ruled surfaces also appear in two ways.The first is constructed with the curve rλ(s)=r(s)+λT(s)and the non-isotropic vector D.The second is formed by the curve rλ=r(s)+λ2N+λ3B and the non-isotropic vector D.We calculate the distribution parameters of the constructed ruled surfaces and we show that the ruled surfaces are developable.Finally,we provide examples and visuals to back up our research.展开更多
The Red-Thai Binh River system is an important water resource to the Northern Delta, serving the development of agriculture, people’s livelihood and other economic sectors through its upstream reservoirs and a system...The Red-Thai Binh River system is an important water resource to the Northern Delta, serving the development of agriculture, people’s livelihood and other economic sectors through its upstream reservoirs and a system of water abstraction works along the rivers. However, due to the impact of climate change and pressure from socio-economic development, the operation of the reservoir system according to Decision No. 740/QD-TTg was issued on June 17, 2019 by the Prime Minister of Government promulgating the Red-Thai Binh River system inter-reservoir operation rules (Operation rules 740) has some shortcomings that need adjustments for higher water use efficiency, meeting downstream water demand and power generation benefits. Through the results of water balance calculation and analysis of economic benefits from water use scenarios, this research proposed adjustment to the inter-reservoir operation during dry season in the Red River system. The result showed that an average water level of 1.0 - 1.7 m should be maintained at Hanoi during the increased release period.展开更多
Dissociations in the gas phase of small molecules have been intensively studied and dissociation energies of various gases are available in reference works. Configurations of compounds before and after the dissociatio...Dissociations in the gas phase of small molecules have been intensively studied and dissociation energies of various gases are available in reference works. Configurations of compounds before and after the dissociation are usually known</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">but local charges are not defined. Building on the even-odd rule, the topic of a series of previous articles by the same author, the objective of this paper is to show how it can be used to give electronic rules for dissociations in gases. To this end, a specific periodic table is created and used. The rules are applied to a selection of more than 30 common molecules, showing that the even-odd rule and its consequences are useful in explaining the phenomenon of dissociation in gases.展开更多
Objective:To analyze the basis and medication rules of Chinese herbs in the regulation of necroptosis.Methods:With the help of GeneCards,DrugBank,TTD,DisGeNET,OMIM database to collect the action targets of necroptosis...Objective:To analyze the basis and medication rules of Chinese herbs in the regulation of necroptosis.Methods:With the help of GeneCards,DrugBank,TTD,DisGeNET,OMIM database to collect the action targets of necroptosis,the TCMSP database to obtain the target‑related compounds and Chinese herbs,and the ADME criteria and Lipinski rule as the conditions for screening,to build the target‑compound,target‑compound‑Chinese herbs network.The information of Chinese herbal medicine's sexual taste and meridian was collected,and the drug use pattern was analyzed.The information on the property,flavor and channel tropism of Chinese herbs was collected to analyze the medication laws.Molecular docking of core targets and compounds in the network with AutoDockTools software,and PyMOL software was used to display the combinations with good docking results.Results:A total of 12 potential targets acting on necroptosis were obtained,matching to 191 candidate compounds and 366 herbal medicines.Quercetin,wogonin,triptolide,licochalcone a,ellipticine are more important and may be the main small molecule substances underlying the regulation of necroptosis.The more important Chinese herbs are Licorice,Forsythia,Salivae Miltiorrhizae,Ginkgo Leaf,Eucommia ulmoides Oliv,etc.The herbal medicines are mainly bitter and pungent,with cold and warm taste,which were attributed to the liver and lung meridians.BCL2‑beta‑sitosterol、MAPK14‑luteolin、MAPK14‑formononetin、TP53‑formononetin are better molecular docking results,which have strong docking activity.Conclusion:The study systematically analyzes the material basis of regulating necroptosis and summarizes the general rule of regulating necroptosis in Chinese medicine,which provides ideas for clinical development of agents to interfere with necroptosis.展开更多
文摘Association rule learning(ARL)is a widely used technique for discovering relationships within datasets.However,it often generates excessive irrelevant or ambiguous rules.Therefore,post-processing is crucial not only for removing irrelevant or redundant rules but also for uncovering hidden associations that impact other factors.Recently,several post-processing methods have been proposed,each with its own strengths and weaknesses.In this paper,we propose THAPE(Tunable Hybrid Associative Predictive Engine),which combines descriptive and predictive techniques.By leveraging both techniques,our aim is to enhance the quality of analyzing generated rules.This includes removing irrelevant or redundant rules,uncovering interesting and useful rules,exploring hidden association rules that may affect other factors,and providing backtracking ability for a given product.The proposed approach offers a tailored method that suits specific goals for retailers,enabling them to gain a better understanding of customer behavior based on factual transactions in the target market.We applied THAPE to a real dataset as a case study in this paper to demonstrate its effectiveness.Through this application,we successfully mined a concise set of highly interesting and useful association rules.Out of the 11,265 rules generated,we identified 125 rules that are particularly relevant to the business context.These identified rules significantly improve the interpretability and usefulness of association rules for decision-making purposes.
文摘This paper reviewed the literature on medication rule of pulmonary nodules in recent years. It is found that contemporary doctors pay more attention to regulating Qi, clearing heat and detoxifying, eliminating phlegm, dissolving phlegm and dissipating masses. They use mild drugs, cold and warm treatments in parallel, combining the tastes of pungent, bitterness, and sweetness at the same time. The treatment focuses on the five viscera with emphasis on the lung meridian while also considering the spleen and stomach functions as well as soothing liver stagnation. This information aims to provide some reference for clinical treatment of pulmonary nodules.
基金National College Students’Training Programs of Innovation and Entrepreneurship,Grant/Award Number:S202210022060the CACMS Innovation Fund,Grant/Award Number:CI2021A00512the National Nature Science Foundation of China under Grant,Grant/Award Number:62206021。
文摘Media convergence works by processing information from different modalities and applying them to different domains.It is difficult for the conventional knowledge graph to utilise multi-media features because the introduction of a large amount of information from other modalities reduces the effectiveness of representation learning and makes knowledge graph inference less effective.To address the issue,an inference method based on Media Convergence and Rule-guided Joint Inference model(MCRJI)has been pro-posed.The authors not only converge multi-media features of entities but also introduce logic rules to improve the accuracy and interpretability of link prediction.First,a multi-headed self-attention approach is used to obtain the attention of different media features of entities during semantic synthesis.Second,logic rules of different lengths are mined from knowledge graph to learn new entity representations.Finally,knowledge graph inference is performed based on representing entities that converge multi-media features.Numerous experimental results show that MCRJI outperforms other advanced baselines in using multi-media features and knowledge graph inference,demonstrating that MCRJI provides an excellent approach for knowledge graph inference with converged multi-media features.
文摘The objective principles of shiology are mainly reflected in three fields as food acquisition, eaters' health and shiance order. Most of the objective principles in the field of food acquisition have been revealed by agronomy and foodstuff science. This research mainly focuses on 10 principles in the field of eaters' health and shiance order and in addition, there are also five lemmas that extend from the above principles. The 10 principles are the core theory of the shiology knowledge system, which play an important role in the objective principles revealed by human beings and constitute one of the basic principles of human civilization. Compared with the scientific principles of mathematics, physics, chemistry and economics, the principles of shiology have three characteristics as popularity, practicability and survivability. The principles of shiology in the field of eaters' health are all around us, and everyone can understand and master them. Using the principles of shiology can improve the healthy life span of 8 billion people. The principles of shiology in the field of shiance order is an important tool of social governance, which can reduce human social conflicts, reduce social involution, improve overall efficiency of social operation, and maintain the sustainable development of human beings.
文摘Breast cancer remains a significant global health challenge, necessitating effective early detection and prognosis to enhance patient outcomes. Current diagnostic methods, including mammography and MRI, suffer from limitations such as uncertainty and imprecise data, leading to late-stage diagnoses. To address this, various expert systems have been developed, but many rely on type-1 fuzzy logic and lack mobile-based applications for data collection and feedback to healthcare practitioners. This research investigates the development of an Enhanced Mobile-based Fuzzy Expert system (EMFES) for breast cancer pre-growth prognosis. The study explores the use of type-2 fuzzy logic to enhance accuracy and model uncertainty effectively. Additionally, it evaluates the advantages of employing the python programming language over java for implementation and considers specific risk factors for data collection. The research aims to dynamically generate fuzzy rules, adapting to evolving breast cancer research and patient data. Key research questions focus on the comparative effectiveness of type-2 fuzzy logic, the handling of uncertainty and imprecise data, the integration of mobile-based features, the choice of programming language, and the creation of dynamic fuzzy rules. Furthermore, the study examines the differences between the Mamdani Inference System and the Sugeno Fuzzy Inference method and explores challenges and opportunities in deploying the EMFES on mobile devices. The research identifies a critical gap in existing breast cancer diagnostic systems, emphasizing the need for a comprehensive, mobile-enabled, and adaptable solution by developing an EMFES that leverages Type-2 fuzzy logic, the Sugeno Inference Algorithm, Python Programming, and dynamic fuzzy rule generation. This study seeks to enhance early breast cancer detection and ultimately reduce breast cancer-related mortality.
文摘Objective:To apply and verify the application of intelligent audit rules for urine analysis by Cui et al.Method:A total of 1139 urine samples of hospitalized patients in Tai’an Central Hospital from September 2021 to November 2021 were randomly selected,and all samples were manually microscopic examined after the detection of the UN9000 urine analysis line.The intelligent audit rules(including the microscopic review rules and manual verification rules)were validated based on the manual microscopic examination and manual audit,and the rules were adjusted to apply to our laboratory.The laboratory turnaround time(TAT)before and after the application of intelligent audit rules was compared.Result:The microscopic review rate of intelligent rules was 25.63%(292/1139),the true positive rate,false positive rate,true negative rate,and false negative rate were 27.66%(315/1139),6.49%(74/1139),62.34%(710/1139)and 3.51%(40/1139),respectively.The approval consistency rate of manual verification rules was 84.92%(727/856),the approval inconsistency rate was 0%(0/856),the interception consistency rate was 12.61%(108/856),and the interception inconsistency rate was 0%(0/856).Conclusion:The intelligence audit rules for urine analysis by Cui et al.have good clinical applicability in our laboratory.
基金sponsored in part by the National Natural Science Foundation of China (Grant No.42001187)Scientific Research Project of Education Department of Hubei Province (No.B2022262)。
文摘Cropland elevation uplift(CLEU) has recently become a new challenge for agricultural modernization,food security,and sustainable cropland use in China.Uncovering the rules of CLEU is of great theoretical and practical significance for China’s sustainable agricultural development and rural revitalization strategy.However,existing studies lack in-depth disclosure of multi-scale CLEU evolution rules,making it difficult to support the formulation of specific cropland protection policies.We analyzed the spatio-temporal evolution and multiscale CLEU in China from 1980 to 2020 using the Lorenz curve,gravity center model,hotspot analysis,and cropland elevation spectrum.The results indicated that the center of gravity of cropland moved to the northeast from 1980 to 2000 and then shifted to the northwest.The spatial distribution of cropland became increasingly imbalanced from 1980 to 2000.The change hotspots clustered in the northwest and the northeast,whereas cold-spots were mainly in southeastern China.The average elevation of cropland increased by 17.38 m,and the elevation uplift rule in different regions differed evidently across scales.From 1980 to 2000,all provinces except Xinjiang,Inner Mongolia,Gansu,and Yunnan exhibited CLEU,with Qinghai,Tibet,Beijing,and Guangdong showing the most noticeable uplifting.The CLEU can alleviate the shortage of cropland to some extent.However,without a planning constraint,the CLEU will lead to the increase of ecological risk and food security risk.
基金supported by the Natural Science Foundation of China (No.61833016)the Shaanxi Outstanding Youth Science Foundation (No.2020JC-34)the Shaanxi Science and Technology Innovation Team (No.2022TD-24).
文摘Fault diagnosis plays an irreplaceable role in the normal operation of equipment.A fault diagnosis model is often required to be interpretable for increasing the trust between humans and the model.Due to the understandable knowledge expression and transparent reasoning process,the belief rule base(BRB)has extensive applications as an interpretable expert system in fault diagnosis.Optimization is an effective means to weaken the subjectivity of experts in BRB,where the interpretability of BRB may be weakened.Hence,to obtain a credible result,the weakening factors of interpretability in the BRB-based fault diagnosis model are firstly analyzed,which are manifested in deviation from the initial judgement of experts and over-optimization of parameters.For these two factors,three indexes are proposed,namely the consistency index of rules,consistency index of the rule base and over-optimization index,tomeasure the interpretability of the optimizedmodel.Considering both the accuracy and interpretability of amodel,an improved coordinate ascent(I-CA)algorithmis proposed to fine-tune the parameters of the fault diagnosis model based on BRB.In I-CA,the algorithm combined with the advance and retreat method and the golden section method is employed to be one-dimensional search algorithm.Furthermore,the random optimization sequence and adaptive step size are proposed to improve the accuracy of the model.Finally,a case study of fault diagnosis in aerospace relays based on BRB is carried out to verify the effectiveness of the proposed method.
基金funded by the National Natural Science Foundation of China (31471968, 31090250, 31372152)supported by grants from the Ministry of Science and Technology of China (MOST Grant 2011FY120200)+5 种基金the Chinese Academy of Sciences (CAS KSCX2EW-Z-2 KSCX2-EW-Q-9)the Bureau of Science and Technology of Yunnan Province to ZYPthe Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)the Department of education of Sichuan Province (13TD0027)
文摘The hot-spring snakes,Thermophis, were previously known only from the Tibet Autonomous Region and Western Sichuan, China. During the past two years, three adult hot-spring snakes (2 females, 1 male) were sampled in Shangri-La, northern Yunnan, China, thus expanding their known distribution region towards the southeast. This site is the southeastern-most corner of the Tibetan Plateau and the southernmost tip of the Hengduan Mountains (Mts.). Phylogenetic analysis of mitochondrial (mt) and nuclear (n) DNA segments suggested that the three specimens belong to the genus ofThermophis. Morphologically, the new species is more similar toT. zhaoermii. However, it is distinguished fromT.zhaoermiiin the number of maxillary teeth (15), distance between the two eyes/head width, rostral width/height, mental width/height, in one character limited to female: head width/length, and in four characters restricted to male: occurrence of the reduction from 10 to 8 (8 to 6, 6 to 4) scales in each dorsal row on the tail. There are differences in morphology, genetics (mtDNA, nDNA), and geography between the putative new species andT.zhaoermii,the new species meets our proposed eclectic and feasible "four-differences" rule.
文摘Ions or molecules are said to be isoelectronic if they are composed of different elements but have the same number of electrons, the same number of covalent bonds and the same structure. This criterion is unfortunately not sufficient to ensure that a chemical structure is a valid chemical compound. In a previous article, a procedure has been described to draw 2D valid structural formulas: the even-odd rule. This rule has been applied first to single-bonded molecules then to single-charged single-bonded ions. It covers hypovalent, hypervalent or classic Lewis’ octet compounds. The funding principle of the even-odd rule is that each atom of the compound possesses an outer-shell filled only with pairs of electrons. The application of this rule guarantees validity of any single-covalent-bond chemical structure. In the present paper, this even-odd rule and its electron-pair criterion are checked for coherence with an effective-valence isoelectronic rule using numerous known compounds having single-covalent-bond connections. The test addresses Lewis’ octet ions or molecules as well as hypovalent and hypervalent compounds. The article concludes that the even-odd rule and the effective-valence isoelectronicity rule are coherent for known single-covalent-bond chemical compounds.
文摘The recently introduced even-odd rule has been shown to successfully represent chemical structures of ions and molecules. While comparing available drawings in the scientific literature with the list of compounds predicted by the even-odd rule, it became however obvious that existing compounds are fewer than expected. Several predicted compounds involving many covalent bonds have apparently never been experimentally observed. Neutral oxygen for instance is expected to have 6 valence electrons, whereas oxygen can only build a maximum of two bonds, as in water. This specificity is observed for elements in the top-right corner of the periodic table. For compounds to contain only single covalent bonds, and thus follow the even-odd rule, further explanations are necessary. The present paper proposes that those specific elements experience a transfer of electrons from the valence shell into the inner shell, making them unavailable for further bonding. These elements will be described as organic, hereby providing a clear and hopefully unifying definition of the term. In opposition, inorganic elements have a constant inner shell no matter their electrical state or the number of bonds they maintain. More than 70 compounds involving 11 elements of the main group are studied, revealing a progression from fully inorganic elements at the left of the periodic table to fully organic elements. The transition between inorganic or organic elements is made of few elements that take an organic form when negatively charged;they are labelled semi-organic. The article concludes that the fully organic elements of the main group are Oxygen and Fluorine, whereas semi-organic elements are more numerous: C, N, S, Cl, Se, Br and I. Thus, the even-odd rule becomes fully compatible with scientific knowledge of compounds in liquid or gaseous phase.
文摘Following the introduction of the new even-odd and isoelectronic rules and definitions affecting the understanding of electronic structure and bonds, the author has thought necessary to summarize understandings in the form of a table. The classical periodic table, a simple tool used by generations of physicists, is here extended to become a useful tool aimed specifically at chemists. In chemistry, position and number of covalent bonds of each atom are needed, as well as the exact location of charges. The table gives the number of possible bonds for each element and reveals how it is affected by charges. Additionally, the specific table indicates for each atom its isoelectronic elements and highlights the distinction between organic and inorganic elements. Discussion is led on the first two rows of the table by successfully comparing its statement with more than 50 well-known liquid and gaseous compounds.
基金the National Natural Science Foundation of China (50275113).
文摘The basic principles of IF/THEN rules in rough set theory are analyzed first, and then the automatic process of knowledge acquisition is given. The numerical data is qualitatively processed by the classification of membership functions and membership degrees to get the normative decision table. The regular method of relations and the reduction algorithm of attributes are studied. The reduced relations are presented by the multi-representvalue method and its algorithm is offered. The whole knowledge acquisition process has high degree of automation and the extracted knowledge is true and reliable.
基金funded by the National Natural Science Foundation of China(Nos.51875420,51875421,52275504).
文摘Themulti-skill resource-constrained project scheduling problem(MS-RCPSP)is a significantmanagement science problem that extends from the resource-constrained project scheduling problem(RCPSP)and is integrated with a real project and production environment.To solve MS-RCPSP,it is an efficient method to use dispatching rules combined with a parallel scheduling mechanism to generate a scheduling scheme.This paper proposes an improved gene expression programming(IGEP)approach to explore newly dispatching rules that can broadly solve MS-RCPSP.A new backward traversal decoding mechanism,and several neighborhood operators are applied in IGEP.The backward traversal decoding mechanism dramatically reduces the space complexity in the decoding process,and improves the algorithm’s performance.Several neighborhood operators improve the exploration of the potential search space.The experiment takes the intelligent multi-objective project scheduling environment(iMOPSE)benchmark dataset as the training set and testing set of IGEP.Ten newly dispatching rules are discovered and extracted by IGEP,and eight out of ten are superior to other typical dispatching rules.
文摘In this paper,we define the curve rλ=r+λd at a constant distance from the edge of regression on a curve r(s)with arc length parameter s in Galilean 3-space.Here,d is a non-isotropic or isotropic vector defined as a vector tightly fastened to Frenet trihedron of the curve r(s)in 3-dimensional Galilean space.We build the Frenet frame{Tλ,Nλ,Bλ}of the constructed curve rλwith respect to two types of the vector d and we indicate the properties related to the curvatures of the curve rλ.Also,for the curve rλ,we give the conditions to be a circular helix.Furthermore,we discuss ruled surfaces of type A generated via the curve rλand the vector D which is defined as tangent of the curve rλin 3-dimensional Galilean space.The constructed ruled surfaces also appear in two ways.The first is constructed with the curve rλ(s)=r(s)+λT(s)and the non-isotropic vector D.The second is formed by the curve rλ=r(s)+λ2N+λ3B and the non-isotropic vector D.We calculate the distribution parameters of the constructed ruled surfaces and we show that the ruled surfaces are developable.Finally,we provide examples and visuals to back up our research.
文摘The Red-Thai Binh River system is an important water resource to the Northern Delta, serving the development of agriculture, people’s livelihood and other economic sectors through its upstream reservoirs and a system of water abstraction works along the rivers. However, due to the impact of climate change and pressure from socio-economic development, the operation of the reservoir system according to Decision No. 740/QD-TTg was issued on June 17, 2019 by the Prime Minister of Government promulgating the Red-Thai Binh River system inter-reservoir operation rules (Operation rules 740) has some shortcomings that need adjustments for higher water use efficiency, meeting downstream water demand and power generation benefits. Through the results of water balance calculation and analysis of economic benefits from water use scenarios, this research proposed adjustment to the inter-reservoir operation during dry season in the Red River system. The result showed that an average water level of 1.0 - 1.7 m should be maintained at Hanoi during the increased release period.
文摘Dissociations in the gas phase of small molecules have been intensively studied and dissociation energies of various gases are available in reference works. Configurations of compounds before and after the dissociation are usually known</span><span style="font-family:Verdana;">, </span><span style="font-family:Verdana;">but local charges are not defined. Building on the even-odd rule, the topic of a series of previous articles by the same author, the objective of this paper is to show how it can be used to give electronic rules for dissociations in gases. To this end, a specific periodic table is created and used. The rules are applied to a selection of more than 30 common molecules, showing that the even-odd rule and its consequences are useful in explaining the phenomenon of dissociation in gases.
基金National Natural Science Foundation Project(No.82174415)Science and Technology Innovation Project of the China Academy of Chinese Medical Sciences(No.CI2021A05054)Science and Technology Innovation Project of the China Academy of Chinese Medical Sciences(No.CI2021A01818)。
文摘Objective:To analyze the basis and medication rules of Chinese herbs in the regulation of necroptosis.Methods:With the help of GeneCards,DrugBank,TTD,DisGeNET,OMIM database to collect the action targets of necroptosis,the TCMSP database to obtain the target‑related compounds and Chinese herbs,and the ADME criteria and Lipinski rule as the conditions for screening,to build the target‑compound,target‑compound‑Chinese herbs network.The information of Chinese herbal medicine's sexual taste and meridian was collected,and the drug use pattern was analyzed.The information on the property,flavor and channel tropism of Chinese herbs was collected to analyze the medication laws.Molecular docking of core targets and compounds in the network with AutoDockTools software,and PyMOL software was used to display the combinations with good docking results.Results:A total of 12 potential targets acting on necroptosis were obtained,matching to 191 candidate compounds and 366 herbal medicines.Quercetin,wogonin,triptolide,licochalcone a,ellipticine are more important and may be the main small molecule substances underlying the regulation of necroptosis.The more important Chinese herbs are Licorice,Forsythia,Salivae Miltiorrhizae,Ginkgo Leaf,Eucommia ulmoides Oliv,etc.The herbal medicines are mainly bitter and pungent,with cold and warm taste,which were attributed to the liver and lung meridians.BCL2‑beta‑sitosterol、MAPK14‑luteolin、MAPK14‑formononetin、TP53‑formononetin are better molecular docking results,which have strong docking activity.Conclusion:The study systematically analyzes the material basis of regulating necroptosis and summarizes the general rule of regulating necroptosis in Chinese medicine,which provides ideas for clinical development of agents to interfere with necroptosis.