A Study on the“Social Behavior”of Zen Poetry Culture:A Case Study of the Sui and Tang Dynasties

During the Sui and Tang dynasties,Buddhism and Zen poetry underwent great development.Zen poetry is diverse in form,strong in personality,and high in achievement.Among the types of Zen poetry are poems,lyrics,and prose,some of which have social attributes closely related to the development of Chinese Buddhism.An analysis reveals that the viewpoints and information conveyed in these poems,lyrics,and prose are positively correlated with the attitudes of the emperors towards Buddhism.When the attitude of the emperor towards Buddhism reached its peak of positivity during the Tang dynasty,there was a change towards a negative correlation with the viewpoints expressed in poetry.

Study on the mechanism of action of Lizhong Tang in ameliorating non-alcoholic fatty liver disease by regulating mitochondrial autophagy

Objective:To investigate the therapeutic efficacy and underlying mechanisms of LiZhong Tang in the context of non-alcoholic fatty liver disease(NAFLD).Methods:High-fat feed was used to induce NAFLD in rats,Blood and liver samples were collected to facilitate a comparative analysis of rat body mass and liver wet weight and calculate the liver index.Liver pathology was observed,while serum transaminase and blood lipid levels were measured.The protein expression levels of PINK1,Parkin,and LC-3II in rat liver were detected using Western Blot analysis.Results:Compared with the control group,the NAFLD rats exhibited a significant increase in body weight,liver wet weight,liver index,transaminase levels,and blood lipid levels.The expression levels of PINK1,Parkin,and LC3-II protein were significantly decreased(P<0.01).Following intervention with Lizhong Tang,rats in each herbal treatment group displayed a decrease in body weight,liver wet weight,liver index,se-rum transaminase,and blood lipid levels.The expression levels of PINK1,Parkin,and LC-3II rebounded(P<0.05),with the high-dose group demonstrating the most pronounced effects(P<0.01).Histopathological examination of liver tissue revealed that rats in the model group displayed disrupted hepatic lobule structure,swollen hepatocytes,disordered arrangement,and a multi-tude of varying-sized lipid vacuoles within the cytoplasm.Conversely,rats treated with different doses of the herbal remedy exhibited improvements in liver tissue pathology,with the high-dose group showing the most notable enhancement.Conclusion:Lizhong Tang can improve NAFLD disease by regulating mitochondrial autophagy.

Clinical efficacy of external treatment with Zi Cao Yang He Tang combined with hormone therapy for granulomatous mastitis and its effect on cellular pyroptosis proteins

Objective:To observe the clinical effect of external application of Zi Cao Yang He Tang combined with dexamethasone ointment in the treatment of granulomatous lobular mastitis in the mass stage and the effect on cellular pyroptosis-related proteins.Methods:Forty patients with granulomatous lobular mastitis were randomly divided into 20 cases in the observation group and 20 cases in the control group.Both groups were given dexamethasone ointment for treatment,and the observation group was treated with external application of Zi Cao Yang He Tang on the basis of the control group.Breast lump vol-ume changes,breast pain and pus symptoms,pathology and histology and immunohistochemistry,cellular death-related indicators expression were compared between the two groups.Results:After treatment,the difference in mass volume of the observation group was significantly greater than that of the control group(16.7±21.5 in the control group and 32.9±27.4 in the experimental group)and the difference between the two groups was statistically significant(P<0.05);the objective remission rate of the patients in the observation group(ORR=85%)was significantly higher than that of the treatment group(ORR=50%,P<0.05).In terms of pus formation rate and pain level,the breast pain score of the observation group was significantly lower than that of the control group after two weeks or three weeks of treatment(P<0.05);the pus formation rate of the observation group was 30%,and the pus formation rate of the control group was 20%,and the difference was not statistically significant(P>0.05).The immunohistochemical expression levels of caspase-1 and GSDMD in the observation group were significantly lower than those in the control group(P<0.05);and in terms of the expression of cellular pyroptosis-related indexes,the expression of GSDMD,cas-pase-1,and NLRP3 in the observation group was significantly lower compared with that in the control group(P<0.05).Conclusion:The efficacy of external application of Zi Cao Yang He Tang combined with dexamethasone ointment in treating granulomatous lobular mastitis in the mass stage is remarkable,which can effectively reduce breast pain,reduce the size of the mass,de-crease the expression of cellular pyroptosisrelated indexes,and have a good anti-inflammatory effect.

Sun Simiao,super physician of the Tang Dynasty

Sun Simiao(58e682 AD)was a celebrated physician of the Tang Dynasty,whose hometown was Huayuan,Jingzhao(today’s Yao county,Shaanxi province).Known as the most long-lived physician in the Chinese medical history,he died in 682 AD at the age of 102 according to precise record.He went through three dynasties,i.e.the Northern Zhou Dynasty(557e581),the Sui Dynasty(581e618)and the Tang Dynasty(618e917).He was worthy of longevity in terms of today’s perspective.When he was young,he devoted himself to the study of Taoism and many other schools of thought instead of accepting government offers to be an official in the Sui and Tang dynasties.Sun worked as a physician for the general public in his whole life.He was also the teacher of Song Zhiwen,Meng Shen and Lu Zhaolin,who were renowned scholars in the early Tang Dynasty.

Reacting to Epidemics:The Innovative Imperial Public Health System during the Late Northern Song Dynasty

Song China was a period in which China experienced a great increase in its population.Concurrently,the Song dynasty also experienced a rise in the frequency of epidemics and two major wars with the Western Xia and Liao dynasties during the 1000s and 1040s.The consequences of these changes were exacerbated by the increased geographical mobility of certain social groups such as traders and examinees attending civil service examinations.Thus,casualties of wars,epidemics,or disease,especially of people whose families were far away and could not care for them were left without care and“their corpses often lay bare along the roads.”This new social environment created a need for general relief.The Northern Song government(960-1127 CE),especially during the reign of Emperor Huizong,established an innovative public health system to address this issue.The public health system included poorhouses,public hospitals,and pauper’s cemeteries.The first were more of charity organizations,whereas the latter two promoted public health by providing medical services for the poor and burial for those that nobody cared for.In terms of rationale behind these institutions,on the one hand,they constituted an attempt to get the poor and homeless off the streets while providing them relief or burial.On the other hand,it seems that Huizong’s deep concern with medicine propelled him to design and implement a comprehensive public health system oriented to prevent contagion and outbreak of epidemics.This article depicts the background,the organization,and the functions of the system.The article also discusses the conditions and reasons that gave rise to such a unique undertaking by the Northern Song government.

Functions of Karez to Xinjiang Agriculture in the Qing Dynasty from the Perspective of Historical Documents

Desertification is increasingly serious in Xinjiang,and the construction of water conservancy is a precondition for the development of agriculture.The main project for the development of agriculture and water conservancy in Xinjiang is to build Karez,which played a vital role in the development of Xinjiang agriculture in the Qing Dynasty.It has been recorded many times in historical documents of the Qing Dynasty,such as Lin Zexu s Diary,Tao Baolian s Diary,Xinjiang Atlas and Zuo Zongtang s Memorial to the Emperor,etc.,which recorded the situation and historical origin of Karez.Karez made a significant contribution to the development of agriculture in the Qing Dynasty.It increased the cultivated land in Xinjiang at that time,and increased the types and yields of crops.It is conducive to the stability and development of Xinjiang s economy.Until today,Karez is still an important water source for agricultural irrigation in Xinjiang.

Looking up Prescriptions to Treat Infectious Disease:Anti-epidemic Books of Medical Formularies and Epidemic Prevention and Control in the Qing Dynasty

Copying,compiling,publishing,disseminating,and referencing anti-epidemic books of medical formularies were common activities during the outbreak of epidemics in the Qing dynasty.Its emergence,motivated by epidemic disease again and again,was important component parts of epidemic prevention and control.They played a unique role as media on affairs such as treating patients suffering from infectious diseases,mobilizing peoples to make contributions to anti-epidemic activities,integrating and popularizing knowledge of epidemic prevention.Anti-epidemic books of medical formularies were important to link peoples,things,and substances related with epidemic prevention and control,and were a kind of motivation to actively deal with the infectious disease,control the epidemic,and maintain health.Compared to other common measures,anti-epidemic books of medical formularies participated in many prevention and control practices deeply,which actually built a low cost,spontaneous,dispersed and non-institutional system to respond to epidemic,and the system had characteristics of stronger conductibility,bigger coverage area,and better external benefits.

A New Inquiry Into the Contents of the Late Qing Dynasty Pictorial News Publication-The Core of “Entertainment Life” in Dianshizhai Pictorial

After the opening of ports in the late Qing Dynasty,Western culture was introduced into China.The local entertainment life presented the phenomenon of the coexistence of the East and the West.A large number of folk entertainment activities were recorded in the Dianshizhai Pictorial which have the function of cultural choice and value dissemination as well as current affairs.This research attempts to use literary analysis and case study to collate the entertainment life in the Dianshizhai Pictorial,combing the characteristics of the late Qing dynasty,and summarizing the value of entertainment in Dianshizhai Pictorial publishing.

Application of Garden Design Style in Tang Dynasty to the Design of Modern City Public Gardens: A Case Study of Tang Paradise

Public garden, as a type of Chinese classical garden, is an important historical heritage and cultural landscape of the current traditional city. However, under the background of modern urbanization, urban living environment is out of the traditional history and culture and facing such issue as cement jungle. In order to improve the living environment and make the city coordinate with the natural environment, the development of modern urban gardens needs inheritance and development of traditional garden practices. The planning and design methods with scientific guidance were studied in this paper through exploring the application of garden design style in Tang Dynasty in the design of modern city public gardens, so as to inherit the classical garden culture and create a city open space that meets the needs of contemporary citizens as well.

Investigation of the mechanism of action of Sanwu Huangqin Tang in the treatment of restless leg syndrome based on network pharmacology,molecular docking technology and molecular dynamics simulation

Background:Through the use of network pharmacology and molecular docking approaches,this study will examine the pharmacological effects of Sanwu Huangqin Tang on restless legs syndrome in order to better understand the mechanism of action of Traditional Chinese medicine(TCM)on RLS.Method:Utilise the TCMSP database to collect and select the drug components of Sanwu Huangqin Tang,and the Uniprot database to identify pertinent targets;RLS-related disease targets were obtained from GeneCards,DrugBank,and OMIM databases;and STRING and Cytoscape 3.9.1 software were used to generate an interaction network.KEGG pathway analysis and GO enrichment analysis were performed utilizing the DAVID database.Use Autodock for analyzing the relationships between targets and core components.Result:By using a network pharmacology approach,83 active ingredients and 50 drug-disease intersecting targets were derived for Sanwu Huangqin Tang.The molecular docking results showed that the drug components had strong affinity with the average target targets.Conclusions:This study provides new insights into the mechanism through which Traditional Chinese Medicine(TCM)treats Restless Legs Syndrome(RLS).Furthermore,it lays the foundation for additional research into the mechanism of treatment for RLS through the intervention that addresses various targets and pathways using the active ingredients identified by Sanwu Huangqin Tang.

Exploration of the mechanism of action of Xiayuxue Tang against hepatic fibrosis based on GEO data mining,network pharmacology and molecular docking technology

Objective:To study the mechanism of action of Xiayuxue Tang in treating hepatic fibrosis by combining GEO data mining,network pharmacology,and molecular docking technology,and provide new research directions for the treatment of hepatic fibrosis.Method:Utilizing multiple databases,we aim to identify the relevant targets of various components in Xiayuxue Tang and their associations with hepatic fibrosis.After pinpointing the key targets through interaction analysis,we will construct both the compound-target network and the protein interaction network for Xiayuxue Tang.Conclusively,we will conduct GO and KEGG enrichment analyses on these key targets,followed by molecular docking verification.Result:Through mining the GEO database,171 related targets were identified.When combined with other databases,a total of 2,343 hepatic fibrosis-related targets were obtained.Xiayuxue Tang comprises 82 related components,which include 26 active components from rhubarb,1 from ground beetle worm,46 from peach kernels,with a total of 314 predicted targets.The GO enrichment analysis revealed 748 biological processes,32 cellular components,and 73 molecular functions,while the KEGG enrichment analysis identified 222 pathways.Molecular docking verification confirmed that effective compounds can bind stably to key proteins,exhibiting strong binding activity.This underscores the potential efficacy of Xiayuxue Tang in addressing hepatic fibrosis.Conclusion:Xiayuxue Tang exerts regulatory effects on hepatic fibrosis through different targets and pathways,suggesting that the herbal compound has the characteristics of multiple pathways and targets.

Mufangji tang ameliorates pulmonary arterial hypertension through improving vascular remodeling,inhibiting inflammatory response and oxidative stress,and inducing apoptosis

Background:Mufangji tang(MFJT)is composed of Ramulus Cinnamomi,Radix Ginseng,Cocculus orbiculatus(Linn.)DC.,and Gypsum.In clinical settings,MFJT has been effectively employed in addressing a range of respiratory disorders,notably including pulmonary arterial hypertension(PAH).However,the mechanism of action of MFJT on PAH remains unknown.Methods:In this study,a monocrotaline-induced PAH rat model was established and treated with MFJT.The therapeutic effects of MFJT on PAH rat model were evaluated.Network pharmacology was conducted to screen the possible targets for MFJT on PAH,and the molecular docking between the main active components and the core targets was carried out.The key targets identified from network pharmacology were tested.Results:Results showed significant therapeutic effects of MFJT on PAH rat model.Analysis of network pharmacology revealed several potential targets related to apoptosis,inflammation,oxidative stress,and vascular remodeling.Molecular docking showed that the key components were well docked with the core targets.Further experimental validation results that MFJT treatment induced apoptosis(downregulated Bcl-2 levels and upregulated Bax levels in lung tissue),inhibited inflammatory response and oxdative stress(decreased the levels of IL-1β,TNF-α,inducible NOS,and malondialdehyde,and increased the levels of endothelial nitric oxide synthase,nitric oxide,glutathione and superoxide dismutase),reduced the proliferation of pulmonary arterial smooth muscle cells(downregulated ET-1 andβ-catenin levels and ERK1/2 phosphorylation,increased GSK3βlevels).Conclusion:Our study revealed MFJT treatment could alleviate PAH in rats via induction of apoptosis,inhibition of inflammation and oxidative stress,and the prevention of vascular remodeling.

The Silk Road:Boosting the Textile Industry in Tang Dynasty

At the height of the Tang Dynasty,trading on the Silk Road reached its peak,which brought opportunities for the development of the textile industry.The Silk Road broadened the domestic and foreign textiles market,influenced Han people’s aesthetic and consumption concepts,and promoted textile trading.The Silk Road expanded the categories of textile products and promoted trading and innovation.It facilitated the exchange of textile technology and formed a virtuous cycle of“export-development overseas-import”.The development of the textile industry relied on both traditional technology and foreign technology,which was reflected in the achievements in printing,dyeing,and brocade,and laid a superb technical foundation for the development of the textile industry later.

The Spread of Chinese-character Culture on the Silk Road During the Tang Dynasty

The spread of Chinese characters and Chinese classic works during the Tang Dynasty presented diversified discourses of acceptance and development in different periods and regions. This was due to the differences in commercial, economic, political, religious, and cultural environments proportional to the real environment's demand for Chinese characters and Chinese classical works. Chinese characters were introduced to Gaochang, Qiuci, Khotan, Korea, Japan, and Vietnam as early as the Han Dynasty, with different development paths in these regions. It is easy to form a long lasting culture spread by Chinese language and characters, as long as official languages are consistent with national or religious languages of the regions. It is difficult to form a long lasting culture spread by official languages and characters if the official languages and characters are inconsistent with either languages of daily life or religious languages. Once there is replacement of official languages and characters, or a change in religious belief, it would cause incompatibility between official languages and daily life languages, Chinese-character culture is bound to decline and gradually fade way. But if there are Han people, they will retain the use of Chinese characters.

Case Records as Medical Stories: A Song-dynasty Doctor’s Narration of His Own Medicine-Xu Shuwei (1080-1154)

The key point in studying or teaching the history of Chinese medicine is on the doctrines underlying it and on its perception of the body,physiology,pathology,and its treatment.Namely,there is often a tendency to focus on reading and analysing the classical canons and therapy-related texts including formularies and materia medica collections.However,focusing on these sources provides us with a one-sided presentation of Chinese medicine.These primary sources lack the clinical down-to-earth know-how that encompasses medical treatment,which are represented,for instance,in the clinical rounds of modern medical schools.Our traditional focus on the medical canons and formularies provides almost no clinical knowledge,leaving us with a one-sided narrative that ignores how medicine and healing are actually practiced in the field.This paper focuses on the latter aspect of medicine from a historical perspective.Using written and visual sources dating to the Song dynasty,clinical encounters between doctors and patients including their families are depicted based on case records recorded by a physician,members of the patient’s family,and bystanders.This array of case records or case stories will enable us to narrate the interaction between physicians and patients both from the clinical perspective and from the social interaction.This paper will also discuss visual depictions of the medical encounter to provide another perspective for narrating medicine during the Song dynasty.Medical case records and paintings depicting medical encounters are exemplary of the potential of Chinese primary sources for narrative medicine.

The Research on the Battle of Yanmen Pass

During the war between Liao Dynasty(907-1125)and Northern Song Dynasty(960-1127),there was a classic battle that happened in Yanmen Pass(located in today’s Dai County,Xinzhou,Shanxi Province,China).It was a well known battle of ancient China because a commander of the Song army named Yang Ye(?-986)was really famous in both classical Chinese fictions and Chinese war history.He is the early protagonist of a famous Chinese classic fiction named The Romance of the Yang family’s generals(written in the 16th century,Ming Dynasty of China).The story of his family also appears in other novels.Besides,in history,he was a general who was active in the early stages of the war between Liao Dynasty and Northern Song Dynasty.The battle of Yanmen Pass(980)was one of the most important battles of Yang’s military career.His combat style especially his cavalry tactic can be summarized through researching this battle.

Discussion on Color Features of Painting in the Tang Dynasty

In the Tang Dynasty, all economy, politics and culture had a profound influence on painting, and promoted its development, which formed a unique painting charm of Tang Dynasty. For the painting thoughts and aesthetic orientation, the foreign religious art has brought the fresh blood for the painting of the Central Plains of China, the open & diverse culture exchanging between foreign and China broadened people’s horizons, enriched the integration and collocation of color. At the same time, the Tang Dynasty's own social fashion made people purchase the luxury, comfortable life, while the noble & elegant and rich & colorful color style were shown in the painting. Therefore, the changes of painting thoughts and aesthetic orientation in Tang Dynasty enriched the painting color and developed the painting naturally.

Contribution and Modern Public Debt:On the Nature of Patriotic Public Debt in the Late Qing Dynasty and the Early Republic of China

There are different opinions about the first modern domestic debt in China.The theorists judge whether a certain public debt has modernity according to whether it has modern public debt form,ignoring the inconsistency between form and content,institutional provisions and actual implementation.The modern nature of public debt must have both the form and content of modern public debt.Based on the analysis of the issuing background,system design,collection and repayment of patriotic bonds in the late Qing Dynasty and the early Republic of China,it is considered that the part of patriotic bonds subscribed by the Qing royal family is still the nature of donation and return,while the part subscribed by ordinary businessmen and people in the early Republic of China has a modern nature.The dual nature of patriotic bonds is closely related to the social background when the bonds are issued.