The basic core traditional C hinese medicine for the prevention and treatment of COVID-19 and its active mechanisms

Background:COVID-19 has had a dramatic impact on human health,economies,societies,and livelihoods around the world.Traditional Chinese medicine(TCM)formulae have played an important role in the prevention and treatment of COVID-19.WHO evaluated the role of TCM in treating of COVID-19 and encouraged other countries to promote the use of TCM formulae.However,the key is to find the basic core traditional Chinese medicine(BC-TCM)among those formulae.Methods:For the first time,we mined the data of TCM formulae in CNIPA and analyzed herb characteristics and association rules.We then determined the BC-TCM and screened main compounds and therapeutic targets.Finally,the potential molecular mechanisms were explored by using enrichment analyses and molecular docking.Results:This study screened 123 patented TCM formulae,including 312 herbs.According to frequency statistics and association rules,nine herbs(Gan Cao,Jin Yinhua,Guang Huoxiang,Fu Ling,Huang Qi,Jie Geng,Lian Qiao,Cang Zhu,Ku Xingren)were selected as the BC-TCM.The BC-TCM involved 166 main compounds and 48 therapeutic targets.The active compounds Hederagenin,Spinasterol,Beta-sitosterol,and Liquiritin had high binding activity to the COVID-19 targets 3CL,ACE2,and core targets RELA,HSP90AA1,STAT3,MAPK3,and TP53 according to molecular docking results.Interestingly,Hederagenin might be a potential compound for the prevention and treatment of COVID-19.Conclusion:Our research predicted and confirmed the preventive therapeutic effect of BC-TCM on COVID-19.This has the potential to broaden the scope of TCM,guide people in using clinical formulae,and provide valuable insights for future TCM discovery research.

On the Impact of Western Festivals on Traditional Festivals in China and the Reform of Chinese Festivals

As China steps up its reform and opening up to the outside world,Chinese,especially the young,are becoming increasingly interested in western festivals.However,some traditional festivals in China are left out in the cold.This paper is mainly on the effect of west ern festivals on traditional festivals in China,trying to analyze the reason why it becomes this and it will lead us to face the communion and mixture between the two parties rationally.From the perspective of folk culture,it is necessary for us to find the motive of reform of Chinese traditional festivals.

Journey of Knowing about China——Sidelight of the Visit of African Traditional Leaders Delegation to China

At the invitation of the Chinese Association for International Understanding(CAFIU),a 15-member Delegation of African Traditional Leaders composed of delegates of House of Chiefs of Botswana,House of Chiefs of Zambia,Ministry of Local Government of Department of District and Local Administration of Malawi and WAMA Foundation of Tanzania visited China from November 18 to 29.CAFIU has received

On Chinese Traditional Culture from the Perspective of Cultural Exchange between China and the West

With the strengthening of globalization and closer ties between countries,all-round exchanges and cooperation have become an inevitable trend.In the new era,the cultural exchange between China and the West presents an unprecedented depth and breadth.Chinese traditional culture,which has made great contributions to Oriental culture and even the world culture,has been developed,in the process of constant conflict,digestion,and absorption while entering other countries in the world.The inclusiveness of Chinese traditional culture has made it survive and thrive in absorbing the quintessence of foreign culture,which makes it contain new contents.In the process of Chinese and Western cultural exchanges,some parts of the essence traditional Chinese culture which are ignored should be given certain inclination in policy and guided by strengthening the education of Chinese traditional culture.

Reinstating Traditional Horsemanship of Ethnic Minorities in Southern China by Excavation,Sorting,and Comparative Research

In August 1991,the book Chinese Nation’s Traditional Sports History was published,and it was hailed as the“masterpiece of Chinese folk sports”by academic circles.In this masterpiece,the traditional horsemanship of 23 ethnic minorities and that of 10 southern ethnic minorities represented by the Miao,Yi,Bai,Shui,Hani,Naxi,and other ethnic groups has been included.For the first time,this masterpiece integrates the traditional horsemanship of the ethnic minorities in Southern China in one volume.The disadvantage is that most of the included traditional horsemanship of ethnic minorities only made a brief introduction to the time,place,and form of its development.However,under the global trend of the transition from traditional society to modern society and post-modern society,the traditional horsemanship of ethnic minorities in Southern China is facing an increasingly serious crisis of inheritance and disconnection,resulting in a gradual extinction of related traditional cultural heritage.The characteristics are gradually lost because of it.Therefore,it is essential to return to the historical and cultural field of traditional horsemanship,conduct rescue excavation,sort out the traditional horsemanship of ethnic minorities in Southern China,rescue the records of traditional horsemanship that is disappearing or undergoing drastic changes,as well as carry out comparative studies on this basis.This is not only an important way to inherit the traditional culture of ethnic minorities,but also means to protect the diversity of ethnic cultures and promote the development of exotic villages.

A time-space network-based model for transportation service optimization of China Railway Express

This paper describes the development and optimization plans for the China Railway Express(CR Express).As a new type of international land transport organization,CR Express has emerged with the continuous expansion of China toward European investment and trade,and in particular,has expanded with the continuous progress of the One Belt and One Road(OBOR)initiative.In addition to improving the service quality of CR Express,the operating costs must be reduced for developing“smart railways”that serve“smart cities”.We propose a dualobjective-based function mathematical optimization model;the satisfaction of the cargo owner is considered,and the timeliness,transportation capacity,and goods category constraints of CR Express transportation are designed.Moreover,we present the normalized equivalent method of the two-objective function of the model.Finally,a case study is conducted against the background of certain trains in the western corridor of CR Express to validate the effectiveness of the model and research methods proposed in this study.

Street Space in Traditional Settlements in Mountainous Area of North China

With mountainous area of North China as the research objective,the study analyzed street space in traditional settlements in mountainous area of North China from the perspective of form,structure and culture,hoping to find some methods and laws that could be served as the reference for the design of living environment in future.

Spatial Distribution of Traditional Chinese Villages and Factors Affecting Their Distribution

Traditional Chinese villages are precious historical and cultural heritage and special tourist attractions. This study took 646 traditional villages that announced by the government in 2012 as an example to analyze the spatial structure of the traditional villages in China by means of GIS spatial analysis tools and quantitative analysis methods, namely the nearest distance index, geographic concentration index, Gini coefficient and Lorenz curve. The results showed that:(1) in terms of the spatial distribution density, the average density of traditional villages in 29 provinces(cities, districts) was 0.70/10,000 km^2, showing a large provincial gap;(2) as for the type of spatial distribution, there was a cluster distribution; and(3) on the balance of spatial distribution, there were many differences between the east and west, and the distribution was extremely uneven. Based on the above, this study explored the reasons for the uneven spatial distribution, including the natural environment, population migration, the level of traffic accessibility, the degree of government attention, and the level of economic development.

In vitro screening of traditionally used medicinal plants in China against Enteroviruses

AIM： To search for new antiviral agents from traditional Chinese medicine, specifically anti-enterovirosuses agents. METHODS： The aqueous extracts （AE） of more than 100 traditionally used medicinal plants in China were evaluated for their in vitro anti-Coxsackie virus B3 activities with a MTT-based colorimetric assay. RESULTS： The test for AE of 16 plants exhibited anti- Coxsackie virus B3 activities at different magnitudes of potency. They can inhibit three steps （inactivation, adsorption and replication） during the infection. Among the 16 plants, Sargentodoxa cuneata （Oliv.） Rehd. et Wils., Sophora tonkinensis Gapnep., Paeonia veitchii Lynch, Spatholobus suberectus Dunn. and Cyrtorniurn fortunei J, sm. also have activity against other enterovirus, including Coxsackie virus 135, Polio virus I, Echo virus 9 and Echo virus 29. Cell cytotoxic assay demonstrated that all tested AE had CC50 values higher than their EC50 values. CONCLUSION： The sixteen traditionally used medicinal plants in China possessed antMral activity, and some of them merit further investigations.

The Inheritance and Development of Chinese Narrative Medicine Practice to the Philosophical Wisdom of Traditional Chinese Medicine

Starting from the inheritance and promotion of Chinese life philosophy and traditional Chinese medicine wisdom by Chinese narrative medicine practice,this paper discusses the inheritance and echo relationship between the“close textual reading ability”in Chinese narrative medicine practice and the“four diagnoses”in traditional Chinese medicine wisdom,narrative mediation and the“mind-body holistic philosophy”in traditional Chinese medicine,and narrative wisdom and Dao Sheng in Chinese life philosophy.Meanwhile,by analyzing the stories of contemporary doctors’practice of narrative intelligence,this paper expounds that Chinese narrative medicine is a new model of medical education and clinical practice based on the absorption of Chinese traditional life wisdom and the essence of traditional Chinese medicine culture,and the integration of western narrative medicine concepts.It also advocates Chinese scholars to actively build the discipline of“narrative traditional Chinese medicine,”constantly translate the academic achievements to foreign countries,and create a good narrative ecology of traditional Chinese medicine.

Struggling Between Tradition and Modernity: A Feminist Interpretation of Yu Opera China Women

Yu Opera China Women (some translated it into Our Company)(2000) has been well received by audiences for its simple folk description, vivid characters, touching story lines, stunning stage backgrounds, and exquisite stage performances. The opera describes a story of Xiangxiang and Huanhuan, mother-in-law and daughter-in-law, two generations of women in the reform and opening up years in the 20th century in China. These Chinese women try to break the shackles of fate, with the strength to overcome hardships, work hard to gain wealth, and be brave to pursue true love, so it has a strong sense of feminism. However, rooted in the deep traditional Chinese culture, Xiangxiang and Huanhuan are always struggling between tradition and modernity and they make difficult choices along with the awakening of women’s consciousness.

Landscape Spatial Characteristics of Streets and Lanes in Traditional Towns of Sichuan and Chongqing in China

The physical space and viewing perception of streets and lanes in traditional towns of Sichuan and Chongqing in China are deeply influenced by the terrain conditions of the area.The adaptation of the geographical environment with the change of the terrain height difference creates rich spatial rhythm changes in the spatial continuity and opening and closing processing of streets and lanes.The aspect ratio of building elevation and street front of frontage makes the street and lane scale adapt to the different functional requirements of business and life.At the same time,the changeable terrain height difference creates the composition level of street landscape perception of close shot,medium shot and long shot,which constitutes the unique regional charm of streets and lanes in traditional towns of Sichuan and Chongqing.

Approaches and Perspectives of the Westward Spread of Traditional Chinese Medicine: A Case Study of the Radicis Chynae

Some Western scholars have re-examined the concept of“Chinese medicine”and its knowledge system under the influence of global history research methods in recent years,in an attempt to understand the factors that led to the spread of Chinese medicine around the world,and what kind of Chinese medicine is constituted outside of China.Thus,researchers have studied the initial stage of traditional Chinese medicine(TCM)’s entry into the western world,tracing its roots and observing new knowledge systems formed in the process of cross-cultural communication.Responding to the research of Western scholars,this paper studies the Radicis Chynae(《中国根书简》Letters on Chinese Root),a monograph written by Andreas Vesalius,a famous European anatomist who lived in the 16th century.The author of this article examined the understanding and interpretation of Chinese medicine by the European intelligentsia from 16th to 19th century,investigated the influence of the westward spread of TCM on the scientific revolution and medical progress in Europe,and analyzed its relationship with the rise of Sinology in Europe.This article discusses the knowledge interaction between Chinese medicine and the formation of modern European medicine from the perspective of global history and cross-culture.

Diversity of China's Wedding Traditions and Customs

“Raise your bridal veil and let me have a close look at your face. Your brows are so thin and long, like the crescent in the sky. Your brows are so thin and long, like the bow-shape moon.”By singing this melodious Uygur love song, I cannot help imagining the unique ethnic weddings of Uygur lovers and recalling the fascinating panorama of "the Second China Cultural Festival on Ethnic Wedding Traditions" recently hosted in Butterfly Lovers Park in Ningbo, a port city in the southeast coast of China.

China's Traditional Music Enters a New Era——Impression of "China National Concert in Spring Festival of Year of Horse" by HK Zhongyue Orchestra

At 11:00 a.m. of February 10, 2002, the"China National Concert in the Spring Festival ofthe Year of the Horse" was solemnly given in thegolden hall of Vienna. The Hong Kong ChineseFolk Music Orchestra, under the direction of thechief inspector and famous conductor

Dignity:the Overlap of the Universal Declaration of Human Rights and Traditional Chinese Culture

Human dignity is the fundamental concept of the Universal Declaration of Human Rights and serves as the theoretical backbone for the international human rights system. Chinese culture has an excellent tradition of treasuring the dignity and value of people. The provisions on dignity in the Declaration can find their historical origins in traditional Chinese culture. The dignity of people has a supreme status and value in traditional Chinese culture. Chinese "etiquette" culture has a long tradition of respecting the dignity of people.Achieving benevolence through etiquette is the basic way to protect human dignity. Etiquette in ancient China was constrained by inequality and historical limitations, but it also had the elements of respecting or honoring others, and had the practical function of respecting, maintaining and achieving human dignity. The effective implementation of etiquette requires the fulfillment of people’s basic needs. Progressing from xiao kang(moderate prosperity) to da tong(great harmony) is the process of approaching the human rights standards of human dignity and equal rights that all nations and all peoples should strive to achieve.

Regulation Progress of Traditional Medicines in China

Let me introduce Chinese medicines. I will speak in Chinese, and I will express myself more clearly. Just now I listened carefully to Professor Werner Knoess, the doctor's report, giving me a deep feeling. As long as it is the medicine, modern or traditional, the general requirements to conform with, are the same, namely, safe, efficient and quality control. We cannot say that because these are traditional medicines.

Inheriting Good Tradition and Expanding Cooperation Fields for New Stage of Friendship:on FES President Beck 's Visit to China

At the invitation of the Chinese Association for International Understanding(CAFIU),a delegation headed by Mr.Kurt Beck,President of FriedrichEbert-Stiftung(FES),visited China from 17 to 20,October 2013.As his first visit to China since taking the office of FES President,President Beck aimed at keeping abreast of China’s political,economic and social development since the 18th National Congress of the CPC as well as renewing the Memorandum of Understanding between CAFIU and FES.