Longitudinal changes in body weight of breastfeeding mothers in the first year after delivery and its relationship with human milk composition:a combined longitudinal and cross-sectional cohort study

Objective:Postpartum weight retention(PPWR)is a common problem among women after childbirth.The main objectives of this study are to understand the changes in body weight of breastfeeding mothers during long-term follow-up and preliminarily explore the relationship between maternal body weight and human milk composition,including macronutrients,leptin,and adiponectin.Methods:The study included a longitudinal cohort(122 mothers),and a cross-sectional cohort(37 mothers).The human milk,maternal weight,and dietary surveys were collected in the longitudinal cohort at different follow-up time points(1-14 days postpartum,2-4 months postpartum,5-7 months postpartum,and 12-17 months postpartum).The maternal body weight was analyzed using the responses in the survey questionnaires.A milk analyzer based on the mid-infrared spectroscopy(MIRS)was used to determine milk composition,and nutrition analysis software evaluated dietary intakes.In the cross-sectional cohort,participating mothers were asked to provide blood and human milk samples and pertinent information related to maternal body composition.Maternal body composition was measured by bioelectrical impedance analysis(BIA),while ELISA analyzed leptin and adiponectin in milk and serum.Results:At 5-7 months postpartum,the PPWR of breastfeeding mothers was(2.46±3.59)kg.At 12-17 months postpartum,the PPWR was(0.98±4.06)kg.PPWR was found to be negatively correlated with milk fat content within 14 days postpartum and positively correlated at 2-4 months postpartum.In addition,the maternal weight and body muscle mass were positively correlated with leptin and adiponectin in milk.Plasma leptin was positively correlated with the mother’s body weight,body mass index(BMI),FAT percentage,and body fat mass,while plasma adiponectin did not correlate with any parameter.The results also indicate that the PPWR did not correlate with leptin and adiponectin in plasma or milk.Conclusions:Breastfeeding mothers may retain considerable weight gain one year after delivery.Human milk composition may be related to changes in maternal body weight.Leptin and adiponectin in breast milk and leptin in plasma are associated with the maternal body composition.This study supports the notion that maternal nutritional status may affect offspring health through lactation,and future research should focus on exploring weight management of postpartum mothers.

Finite element modeling and injury criteria investigation for the lower leg of the Chinese human body under impact loads

The widely used human body injury criteria were established based on the biomechanical response of the EuroAmerican human body,without considering the differences in anthropometry and injury characteristics among different races,particularly the Chinese human body which typically has the smaller body size.The absence of such race specific design considerations negatively influences the injury prevention capability for these populations,and weakens the applicability of injury criteria.To resolve these issues,this study aims to develop a lower leg finite element model of a 50th percentile Chinese male.The model is built based on the medical images of an average size Chinese male with detailed ankle ligaments and lower leg muscles modeled.Data from sixty experiments available in the literature are used to validate its biofidelity.Using the validated model,the lower leg model is subjected to combined axial compression and bending loads to evaluate its injury criteria.Compared with a typical Euro-American human body mode,the Chinese lower leg presents reduced mechanical tolerance,and the revised tibia index may be an appropriate injury criteria for the Chinese lower leg.Additionally,the validated model reproduces the pedestrian lower leg fracture in a domestic accident.

Reflections on the Improvement of Rural Human Settlement Environment from the Perspective of Beauty and Livability

The construction of beautiful and livable villages is one of the important tasks of ruralrevitalization in the new era, and the development of rural areas attaches more and more importanceto the improvement of human settlement environment. By investigating the construction status andexisting problems of Zhaoba Village in Nanjing, it tries to take “beauty” and “livability” as the planningrequirements. The village positioning is planned accurately, and the functional layout is carried outreasonably. According to the characteristic industries, landscape features and infrastructure of ZhaobaVillage, humanized construction strategies are put forward, thus improving the quality of human settlementenvironment in Zhaoba Village.

Changing Characteristics of Comfort Index of Human Body in Bengbu City in the Past 40 Years under the Background of Climate Change

Based on the daily meteorological data of Bengbu City during 1981-2020,the changing characteristics of three elements needed for the calculation of the comfort index of human body(CIHB)were discussed,and daily CIHB was classified and discussed.The results show that from 1981 to 2020,annual average temperature tended to increase significantly.Annual average wind speed and relative humidity showed a decreasing trend before 2011 but an increasing trend after 2011.The duration of the four seasons in Bengbu City mainly rose in spring,reduced in winter,declined first and then increased in summer,and rose first and then decreased in autumn.As CIHB was at grades 1 and 9(the most uncomfortable),the three factors had different effects on them.For cold weather,the influence of relative humidity and wind speed on CIHB can not be ignored besides temperature.In hot weather,the influence of temperature was dominant,and the change of annual average temperature could well correspond to the change in the number of very hot days.In the context of climate warming,the number of cold days tended to decline generally,but it was larger in the years with fewer very cold days.Under the background of climate warming,there was no obvious change in the number of days of the overall comfort of human body.The number of hot days was closely related to the duration of summer,and the number of days of grade 8 rose significantly in the years with an increase in the duration of summer.

Curved Spine:The Shape of Spine in Taoist Body Diagrams and Its Influence on Medical Body Diagrams

From the early Taoist diagrams of the human body to the end of the Qing dynasty and the beginning of the Republic of China,Taoists exaggerated and deformed the human spine in a shape-shifting manner.It is likely that medical practitioners were influenced by this style of representation,and there are also numerous diagrams of the human body with the curved spine in the lateral-view diagrams of viscera and Ming Tang Tu(明堂图Acupuncture and Moxibustion Chart),which constantly show the human torso in an elliptical“egg shape”.No later than the Ming dynasty,medical practitioners began to depict the actual physiological spinal curve of the human body.By the Qing dynasty,the depiction of the spinal curve in medical diagrams of the human figure showed a tendency to part ways with the Taoist freehand style of the previous generation.Although the representation of the curve of the spine was very crude,later medical images of the human body at least gradually straightened the spine and no longer depicted it in a shape-shifting manner.However,the curved spine in Taoist diagrams of the human body continued to exist,and the presentation of the curved spine never changed.This way of depicting its appearance,which is very different from reality,is shaped by Taoism's special way of perceiving and viewing the body,and may also contain another form of truth.

The levels of osteopontin in human milk of Chinese mothers and its associations with maternal body composition

Objective:This study explored the content and change trend of osteopontin(OPN)in breast milk and analyzed the relationship between OPN in breast milk and maternal body composition.Methods:Breast-feeding mothers were recruited in Xinhua Hospital to collect breast milk and provide pertinent information.The content of OPN in breast milk was determined by enzyme-linked immunosorbent assay(ELISA).Determination of protein content in human milk was performed via the BCA method.The maternal body composition was determined by the bioelectrical impedance method.Serum glucocorticoid receptorα,adiponectin,insulin,and leptin were determined by ELISA.SPSS 25 was used for statistical analysis.Results:In the longitudinal cohort,106 mothers provided 318 milk samples at different lactation periods.The results indicate that the OPN showed dynamic changes.OPN levels were(343.2±163.5)mg/L during 1-14 days postpartum,(228.4±121.5)mg/L during 2-4 months postpartum,and(204.8±100.6)mg/L during 5-7 months postpartum.The content of OPN was very high in the first 1-14 days postpartum and then decreased.Compared with early postpartum milk,the OPN content of mature milk showed a significant relationship with maternal weight-related parameters.Additional body composition analysis was performed in 88 women at the mature milk phase.The results show that the OPN in milk is related to the mother’s body composition,especially the content of skeletal muscle mass,but not to relevant humoral factors.Conclusions:The levels of OPN in human milk of Chinese mothers showed dynamic changes with the extension of lactation time.The OPN in human milk was related to the mother’s body composition but not related to related humoral factors.

The two-way feedback and passing-way of human body

Two-way feedback of human body was published in 1992. The sensation of two-way feedback of body is a special system of human reaction, which maintains and regulates symmetry and balance of human body. The human two-way feedback reacts to human health. For human overall health and delay decrepitude, it is necessary to pay attention to the stimulations (passive acceptance and initiative interventions) and relevant influences in human body and the stimulative effect. In this paper, the experimental research of stimulation and an example of two-way feedback in human body are given. And lay a foundation of prevention, medical treatment and hygiene of human overall health.

Enhancement of the Beauty of Human Landscape Based on Metro Artistic Dimension： A Case Study of Line 1, Line 2, and Line 3 of Xi＇an Metro

As a means of transportation to reduce traffic congestion, the metro has drawn increasing attention. In order to effectively enhance the beauty of the city's human landscape, authors of this paper, based on the public art dimension of metro, explore the artistic expression, problems, and countermeasures related to the enhancement of the beauty of human landscape, and solutions to the common failing of metropolises in the evolution of urban civilization, so as to optimize and spread the urban culture. It is hoped that this paper can cover the shortage of relevant domestic and international studies and provide a theoretical reference for the majority of man-made landscape researchers.

The scientific hypothesis of an 'energy system' in the human body

This paper proposed the scientific hypothesis that human beings have an 'energy system' inside their body and put forward the necessity to propose the hypothesis.In details,this paper explained the hypothesis from its existence,composition,functions,and possible verifying methods.This paper argues that the human body includes both visible and invisible parts.The former is the material system and the latter is the energetic system.As matter and energy can be converted into each other,it is important to study the human body from the perspective of both the material and energetic systems,which can complement each other.The nature of the energetic system is different from that of the material system.The traditional Chinese medicine (TCM) perspective is based on energy;therefore,extending research on the human energy system may lead to the establishment of a modern TCM research field that is firmly grounded in the principles of TCM.Such a research field might generate novel findings.

Quantum theory-based physical model of the human body in TCM

In the study,a quantum resonant cavity model based on wave-particle duality was proposed for the explanation of the dynamic processes of essence,vigor,and spirit in the human body in traditional Chinese medicine(TCM).It is assumed that there is a macro human order parameter(wave function),and its dynamics are governed by a macro potential field reflecting influences from heaven,earth,and society,and satisfy the generalized Schrodinger equation.This proposed model was applied in the study to interpret basic concepts of human body in TCM,with an aim to unfold the TCM development in the future.

Research on Dynamic Model of the Human Body

After summarizing the current situation of the research on human body modeling, a new dynamic model containing 5 equivalent masses has been proposed and the corresponding dynamic equations has been deduced too. By using this new model, more detailed information about the situation of the human body under impact and vibration can be obtained. The new model solves the problem that transmission functions of forces inside the human body can't be deduced by using 3-equivalent-mass model. It will find its usage in many applications.

X-Ray Vision: The Mental Genealogy of the Anatomy of the Interior of the Human Body

Background: The concepts of the Young Person and of an Elderly Person go through an evolutionary diversification during the Human lifecycle and are permeable to diverse biopsychosocial factors involved in the definition of the lifecycle stages. Therefore, assessing this subjectivity in different stages of development and population fringes may be a determinant key factor to assist the implementation of successful disease prevention and health promotion strategies. Aim: The aim of the present study was to discern how Fine Arts’ college students of the Anatomy class mentally represent the inner morphology of the human body of the Young Person and of an Elderly Person. Method: For such, 126 students were asked to draw the interior of the body of a Young Person and of an Elderly Person. In all, 252 drawings were collected and analysed, based on a coding data grid designed for this purpose. Hence, a comparative analysis of these two different vital lifecycle phases was achieved. Results: The results suggest anatomical differences in the pictorial representation of the Young Person and of the Elderly Person, namely in the accentuation of the curvatures of the vertebral column, retrusion of the lower jaw and muscle flaccidity. Conclusions: Although the body schema was the same for all individuals, the body image was singularly depicted and linked to each individual’s history, representing a synthesis of his idiosyncratic perceptions, experiences and particularities.

Sensitivity Numerical Analysis of Human Body Exergy Balance under an Unsteady-State Thermal Environment —Behavioral Adaptation Induced by Undesirable Cold Storage by Building Envelope in Winter

We analyzed the relationships between the human body exergy balance and behavioral adaptations induced by undesirable cold storage by a building envelope under an unsteady-state thermal environment in winter. The complex interaction of the warm exergy production by shivering, lifting of the shell ratio, and reduction of the blood flow rate was considered to constitute the physiological adaptation necessary for maintaining the constant core temperature, which was an important aspect in living organisms. In the case of intermittent use room, it was suggested that better thermal comfort and desirable behavioral adaptations, which decreased the consumption of fossil fuels, could be achieved if interior wooden cladding was used in constructions with building envelopes that had a comparatively large heat capacity, or in cases of wooden constructions in which the building envelope heat capacity was comparatively small.

Research of Water Response under the Action of the Infrared Human Body Radiation by Water Conductometric Sensors

Non-equilibrium thermal and biothermal radiation generated by heated solid materials and hematothermal living organisms are studied by water conductometric sensors. Engineering aspects and physical features of developed water conductometric sensors are given. Procedure and measuring technique are described. Our experiments show the anomalous behavior of water conductivity and associated differential parameters under water heating by biological objects compared with traditional heating sources. Water response to human action strongly depends on psychophysiological and psychoemotional state of the person. Moreover the responses to the action by left and right human hands are substantially different and as a rule are specific to the gender. The possible physicochemical mechanisms of such anomalous water behavior are studied. It is suggested that the observed effects are associated with resonant excitation of vibration-rotation energy levels of water under the influence of bioradiation generated by human organism consisting of approximately 70% water. The results obtained have good perspectives for future applications in different fields of human activity.

Molecular cloning and characterization of human age-related NADH oxidase (arNOX) proteins as members of the TM9 superfamily of transmembrane proteins

Age-related NADH oxidase (arNOX = ENOX3) proteins are superoxide-generating cell surface oxidases that increase in activity with age beginning at about 30 y. A soluble and truncated exfoliated form of the activity is present in blood and other body fluids. The activity was purified to apparent homogeneity from human urine and resolved by 2-D gel electrophoresis into a series of 24 to 32 kDa components of low isoelectric point. The purified proteins were resistant both to N-terminal sequencing and trypsin cleavage. Cleavage with pepsin revealed peptides corresponding to the TM9 family of transmembrane proteins. Peptide antisera raised to all five members of the human TM9 family sequentially blocked the arNOX activity of human saliva and sera. The soluble truncated N-terminus of the human homolog TM9SF4 was expressed in bacteria. The recombinant protein was characterized biochemically and exhibited ar-NOX activity. The findings identify five arNOX isoforms each of which correspond to one of the five known TM9 family members. The exfoliated soluble arNOX forms are derived from the 24 to 32 kDa N-termini exposed to the cell’s exterior at the cell surface. Each of the shed forms contain putative functional motifs characteristic of ECTO-NOX (ENOX) proteins despite only minimal sequence identity. Our findings identify arNOX as having functional characteristics of ENOX proteins and the TM9 superfamily of proteins as the genetic origins of the five known arNOX isoforms present in human sera, plasma and other body fluids1.

MATHEMATICAL STUDY OF DIFFUSIVE FLUID TRANSPORT AND DISTRIBUTION IN HUMAN DERMAL REGIONS

This paper deals with mathematical study of diffusive fluid transport and distri- bution in human dermal parts. It accounts the intracellular fluid which continuously flows through the skin shells in order to maintain fluid balance within the body. A mathematical model is envisaged for this process and the finite element method （FEM） is employed to calculate the concentration of the fluid at different skin layers. This estimation is analyzed in relation with other parameters of the tissue medium and the atmosphere.

Malakoplakia of the esophagus caused by human papillomavirus infection

Malakoplakia is a rare granulomatous disease probably caused by infection and characterized histologically by Michaelis-Gutmann bodies.We report a more rarely seen case esophageal malakoplakia in a 54-year-old woman.She presented with coughing while eating and drinking.Gastroscopy showed yellow nodules in the esophagus,and endoscopic ultrasonography showed a space-occupying lesion in the substratum of the esophageal mucosa.All findings highly resembled esophageal cancer.Histopathological examination finally indentified this space-occupying lesion as malakoplakia and not cancer.Immunohistochemistry showed that she had human papillomavirus(HPV) infection in the esophagus,which indicates that infection was responsible for the malakoplakia.This is believed to be the first case of malakoplakia in the esophagus,and more importantly,we established that HPV infection was the initiator of esophageal malakoplakia.

A NEW TWO-DIMENSIONAL "MAN-WCV" MATHEMATICAL MODEL OF THE HUMAN THERMOREGULATION

In the paper a new two-dimensional 'man-WCV'(water cooling vest) mathematical model is developed. This model is of practical use: it can predict transient temperature responses and body temperature distribution for a person in a nonuniform hot environment, doing various jobs and dressed in different clothes. In addition, the results calculated from the model can be used to optimize the distribution of the tube-net lined on the WCV and to evaluate an individual thermal conditioning system with cooling water. The results obtained from the model agree well with the author's experimental data.

The Meanings and Application of Body Language

As the society is developing,people communicate more and more fiequently,therefore,the massages interpreted by body language become more and more important in human communication.What's more,body language becomes increasingly crucial in teaching and learning.Thus,it is necessary to study body language in order to develop human communication skills.

Measuring the Association of Overweight and Obesity with Human Disease and Other Factors in Bangladesh

Overweight and obesity in people are epidemic in North America and internationally. In the United States, the number of overweight children and adolescents has doubled in the last two to three decades, and similar increasing rates are being observed worldwide, including developing countries as Bangladesh where an increase in Westernization of behavioral and dietary lifestyles is evident. Human diseases associated with overweight and obesity are similar in children as in the adult population. The main purpose of this study was to examine the association between overweight and obesity with human disease and other factors in Bangladesh. We have attempted to estimate the relationship between associated variables by using the Pearson Chi-Square test. It also showed how important an individual variable is by itself. The study also employed a statistical technique namely, logistic regression analysis which has been used to find out the association of overweight and obesity with human disease and other factors. We have seen that 16.96% people are overweight and 4.14% people are obese, i.e. 21.1% people are overweight or obese in Bangladesh. From the logistic regression analysis technique among the independent variables type of place of residence, Highest educational level, Wealth index, Current marital status, Ever had vaccination, Had fever in last two weeks, Had cough in last two weeks, Short, rapid breaths, Problem in the chest or blocked or running nose have significant effect on dependent variable BMI classification.