Hypoglycemic Effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi Green Tea and Their Compatibility on Mice

[Objectives]To explore the hypoglycemic effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi green tea and their compatibility on mice,so as to provide more options for the adjuvant treatment of diabetes and improve the comprehensive utilization value of Guixi green tea.[Methods]After being fed adaptively for 7 d,60 SPF-grade male mice were intraperitoneally injected with alloxouracil(180 mg/kg)to induce hyperglycemia model,from which 35 mice with a successful model were selected.They were randomly divided into 5 groups(Danshen group,green tea group,compatible group,positive control group and blank control group),with 7 animals in each group.The mice in all groups were administered according to the dose of 200 mg/kg once a day for 15 d.After the last administration,their body weight was measured on the 15 th day after fasting for 12 h,and their fasting blood glucose was measured by tail clipping.[Results]After modeling,the mice in each group showed typical hyperglycemia symptoms,namely obvious polydipsia,polyphagia,polyuria and weight loss.Compared with the blank control group,Danshen group and green tea group had obvious hypoglycemic effect(P<0.05),and compatible group had significant hypoglycemic effect(P<0.01).Compared with the blank control group,the weight loss of diabetic mice could also be inhibited in green tea group and compatible group(P<0.05).[Conclusions]Danshen,Guixi green tea and their compatibility had the effect of lowering blood sugar,among which the compatible group had the most obvious effect.

Effects of Radix Puerariae, Radix Rehmanniae and Their Compatibility on Blood Glucose and Blood Lipids in Mice

[Objectives]To explore the effects of the compatibility of Radix Puerariae and Radix Rehmanniae on blood glucose and blood lipids in diabetic mouses.[Methods]Diabetic mouse model was established.The body weight and fasting blood glucose of mice were measured after 7 and 14 d of administration,and the biochemical indicators of blood lipids(TC,HDL-C,and LDL-C)were detected after 14 d of administration.[Results]Compared with the Radix Puerariae group and Radix Rehmanniae group,the compatibility group(1:2)had the best hypoglycemic effect(P<0.05),and TC and LDL-C in the compatibility group(2:1)significantly decreased(P<0.05),while HDL-C in the compatibility group(1:1)significantly increased(P<0.05).[Conclusions]Radix Puerariae,Radix Rehmanniae and their combination can reduce the blood glucose of diabetic mice.The compatibility group(1:2)had a significant hypoglycemic effect(P<0.05),and LDL-C in the compatibility group(2:1)significantly declined,while HDL-C in the compatibility group(1:1)rose significantly.

Based on the Advantages of Acupuncture and Moxibustion Therapy, the Multiple Exploration of the Correlation between the Meridians and the Circulatory System of the Nervous System

The meridians,nervous system,and circulatory system are important components of tra‐ditional Chinese medicine and modern medicine.The meridians have a high degree of consistency with the distribution of the nervous and circulatory systems in modern medi‐cine,and are closely related in the process of disease treatment.Therefore,people often confuse the three.Based on the great advantages of acupuncture and moxibustion in the treatment of nervous system and circulatory system diseases,the author has made diver‐sified exploration on its relevance in terms of origin,physiological anatomy,physiological function and clinical application.It is believed that meridians have their relative indepen‐dence,and the nervous and circulatory systems cannot completely replace meridians.However,meridians are closely related to the nervous and circulatory systems,and in clinical practice,meridians can be combined with the nervous and circulatory systems to guide the treatment of diseases.

Forty-five Cases of Apoplexy Treated by Electroacupuncture at the Points of Yin Meridians

Forty-five cases of apoplexy were treated by electroacupuncture only at the points of Yin Meridians (i.e. the Hand- and Foot-Taiyin Meridians), and the other 30 cases as the controls were treated only at the points of Yang Meridians (i.e. the Hand- and Foot-Yangming Meridians). The total effective rate was 91.1% in the former and 86.7% in the latter, with no statistically significant difference between the two groups, indicating that acupuncture only at the points of Yin-Meridians is also an effective therapy for apoplexy.

STUDY ON THE STARCH GRAFTED ACRYLATE MONOMERS AND ITS COMPATIBILITY FOR THE BLEND SYSTEM OF STARCH AND POLYETHYLENE

By means of initiation of the high temperature and shearing stress of an extruder,we synthesized the graft copolymer of starch with acrylate monomers based on the simple dry method.The effects of reaction conditions on graft copolymerization were discussed. Grafted starch used as a compatibilizer for the blend system of starch and polyethylene was further investigated. The results indicate that grafted starch as a compatibilizer can improve the mechanical properties and rheologic properties of the blend of starch and polyethylene.

The Compatibility of Pragmatic Twist and Rhetoric

It is universally believed that Rhetoric is an expressive way of language, while pragmatic twist(Deliberate misinterpretation) isthe understanding phenomenon, which is not a rhetorical device but a cognitive activity in nature. The two can't be placed on a par witheach other. However, we find that the two aren't incompatible at all. The second speaker(S2) captures the rhetorical device in the firstspeaker(S1)'s utterance, and distorts the original meaning to achieve S2's communicative goal.

Construction and Research Progress of the Chinese Meridian Project in 2022–2023

The Chinese Meridian Project(CMP)is a major national science and technology infrastructure constructed in two steps.The first phase of the CMP has been operating for more than a solar cycle.From 2022 to 2023,utilizing the monitoring data collected by the CMP,scientists made major breakthroughs in fields of ionosphere,middle and upper atmosphere,and coupling between layers.The construction of the second phase of the CMP is nearly finished,and the project is expected to operate as a whole in 2025 after national acceptance of the second phase.The whole project was built in an architecture of so-called“One Chain,Three Networks and Four Focuses”.It is promising to make a three-dimensional observation of the whole solar-terrestrial space.The science community is looking forward to the great contribution of the CMP to space weather and space physics research.

Network pharmacology to decipher the mechanism of Danggui Longhui Wan against chronic myeloid leukemia

Chronic myeloid leukemia(CML)is a hematopoietic myeloproliferative disorder.The Chinese prescription Danggui Longhui Wan(DGLHW)has been utilized in CML treatment,but its underlying mechanisms remain unclear.In this study,we gathered 794 constituents,1249 drug targets,1654 disease genes and 129 intersection genes.GO and KEGG were used to analyze the function of these genes.Compatibility of prescription study showed that monarch drug,minister drug,assistant and guide drug played a synergistic role in the treatment of CML.In addition,we obtained 20 hub genes and 12 key components.Molecular docking indicated that the main compounds and core proteins had good binding ability.The results of this study also showed that DGLHW might play a role in the treatment of CML by affecting MAPK,PI3K/AKT,FoxO and p53 signaling pathways.

Solution of the Matrix Second Semi-Tensor Product Equation A ∘ l X ∘ l B=C

In this paper, the solution of the matrix second semi-tensor product equation A∘lX∘lB=Cis studied. Firstly, the solvability of the matrix-vector second semi-tensor product equation is investigated. At the same time, the compatibility conditions, the sufficient and necessary conditions and the specific solution methods for the matrix solution are given. Secondly, we further consider the solvability of the second semi-tensor product equation of the matrix. For each part, several examples are given to illustrate the validity of the results.

The Assessment of the Clinical Effect of the Drug Compatibility and Course of Treatment to the Brucellar Spondylitis

Objective: To evaluate five drug treatment regimens in the treatment of Brucella spondylitis. Methods: Patients with clinical symptoms compatible and diagnostic test consistent with Brucella spondylitis were randomly assigned to five drug treatment regimens. Results: Combination therapy with doxycycline, rifampin and sulfamethoxazole for 56 consecutive days showed the highest cure rate of 20% after a single course and of 85% after a double course with affectivity rates of 55% and 95%. Cure rate and affectivity rate was significant better (P 0.05) than for patients receiving doxycycline, rifampin and streptomycin for the same period and regimens containing doxycycline were significant better than regimens without this drug. Conclusion: Combination therapy of doxycycline, rifampin and sulfamethoxazole for 8 weeks using one or two full courses should be recommended for Brucella spondylitis.

Formation mechanism of propagated sensation along the meridians,as verified by cortical somatosensory-evoked potential topographic maps

The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering the central nervous system. Accordingly, volunteers have reported propagated sensations along the meridians （PSM）. The present study was designed to utilize a cortical somatosensory-evoked potential （CSEP） topographic map for determining whether stimulation expansion occurs in somatosensory area I when sensation was provoked in individuals with obvious PSM. The sensation was blocked by mechanical compression, and the sensation was imitated in individuals without PSM. Results revealed a red, high-potential signal in the representative area of the lower limbs in individuals with obvious PSM symptoms when the Gall Bladder Meridian （GBM） sensation passed to the head and face. This representative area was near the middle line of the CSEP topographic map, and a red, high-potential signal, which jumps over the representative area of the upper limbs, also appeared in the representative face area, which was at the external region of the CSEP topographic map. However, in individuals exhibiting no PSM, only a red high-potential signal appeared in the representative lower limb area. When Hegu （LI 4） was stimulated in individuals without PSM, an obvious evoked response appeared only in the representative upper limb area. However, when Hegu was stimulated in individuals exhibiting PSM, the response area was larger in the representative upper limb area and extended to the representative face area. When Guangrning （GB 37） was stimulated in PSM individuals, the face representation response disappeared and was confined to a foot representation of the somatosensory area I when PSM was blocked by mechanical pressure. Results suggested that mechanical compression blocked PSM, and corresponding changes were exhibited in the CSEP topographic map. These results provide compelling evidence for the hypothesis that peripheral driver stimulation is the key element in producing PSM.

Improvement of HydrophUicity and Blood Compatibility on Polyethersulfone Membrane by Blending Sulfonated Polyethersulfone

Polyethersulfone(PES) is widely used as biomaterials due to its thermal stability,mechanical strength,and chemical inertness.Nevertheless,their blood compatibility is still not adequate for hemodialysis and blood purification.In this study,the sulfonated polyethersulfone(SPES) was synthesized through an electrophilic substitution reaction,and PES/SPES blending membranes were prepared.The characterization of the SPES was studied by FTIR.The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES.Moreover,PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane,thereby improving blood compatibility.

The Compatibility of Polycarboxylate-Type Superplasticizers with Cement

Four polycarboxylate- type （ PC ） superplasticizers of different functional groups were used ; their dispersing and retaining behaviors were analyzed through ZETA potential measurement, mini-slump test of cement paste and performance test of concrete. The experimental results show that the dispersing and flow-retaining ability of PC was determined by two factors of anionic groups and nonionic groups ： the density of anionic groups - COO^- or - SO3^- acted on the electronic repulsive force. and the length and proportion of nonionic graft groups of PEO in PC chemical stracture affected the steric effect. The compatibility between PC superplasticizers and cement mainly depended on the type of PEO groups ; furtlwrmore, adding mineral powders is good to the compatibility for high performance concretes （ HPCs ）.

Purification and characterization of the kinetic parameters of cellulase produced from wheat straw by Trichoderma viride under SSF and its detergent compatibility

This paper reports the purification and characterization of kinetic parameters of cellulase produced from Trichoderma viride under still culture solid state fermentation technique using cheap and an easily available agricultural waste material, wheat straw as growth supported substrate. Trichoderma viride was cultured in fermentation medium of wheat straw under some previously optimized growth conditions and maximum activity of 398±2.43U/mL obtained after stipulated fermentation time period. Cellulase was purified 2.33 fold with specific activity of 105U/mg in comparison to crude enzyme extract using ammonium sulfate precipitation, dialysis and Sephadex-G-100 column chromatography. The enzyme was shown to have a relative low molecular weight of 58kDa by sodium dodecyl sulphate poly-acrylamide gel electrophoresis. The purified enzyme displayed 6.5 and 55oC as an optimum pH and temperature respectively. Using carboxymethyl cellulose as substrate, the enzyme showed maximum activity (Vmax) of 148U/mL with its corresponding KM value of 68μM. Among activators/inhibitors SDS, EDTA, and Hg2+ showed inhibitory effect on purified cellulase whereas, the enzyme activated by Co2+ and Mn2+ at a concentration of 1mM. The purified cellulase was compatible with four local detergent brands with up to 20 days of shelf life at room temperature suggesting its potential as a detergent additive for improved washing therefore, it is concluded that it may be potentially useful for industrial purposes especially for detergent and laundry industry.

Synthesis of LaGaO_3-Based Electrolyte Material and Its Compatibility with Novel Electrode Materials

La_ 1-xSr_xGa_ 1-yMg_yO_ 3-δ(LSGM)electrolyte material was synthesized by solid-state reaction method. The microstructure characteristics were tested via X-ray diffraction(XRD), scanning electron microcopy (SEM), and energy dispersive spectroscopy (EDS). XRD patterns indicate that perovskite phase began to form when the mixed materials were sintered at 1000 ℃, and the material has a pure LSGM perovskite phase when the mixed materials were sintered at 1450 ℃ in air for 24 h. No chemical reaction between LSGM electrolyte material and La_ 1-xSr_xMn_ 1-yCr_yO_ 3-δ(LSMC) anode material or La_ 1-xSr_xFe_ 1-yCo_yO_ 3-δ (LSFC) cathode material was detected after the mixed materials consisting of LSGM and LSMC or LSFC was sintered at 1200 ℃ in air for 15 h respectively, which shows that LSGM electrolyte material has excellent chemical compatibility with LSMC anode and LSFC cathode materials. According to SEM, LSMC anode film and cathode composite film of LSFC and LSMC prepared using direct painting method by sintering at 1150 ℃ are both porous and well cohered on LSGM electrolyte substrate.

Self-compatibility in peach[Prunus persica(L.)Batsch]:patterns of diversity surrounding the S-locus and analysis of SFB alleles

Self-incompatibility(SI)to self-compatibility(SC)transition is one of the most frequent and prevalent evolutionary shifts in flowering plants.Prunus L.(Rosaceae)is a genus of over 200 species most of which exhibit a Gametophytic SI system.Peach[Prunus persica(L.)Batsch;2n=16]is one of the few exceptions in the genus known to be a fully selfcompatible species.However,the evolutionary process of the complete and irreversible loss of SI in peach is not well understood and,in order to fill that gap,in this study 24 peach accessions were analyzed.Pollen tube growth was controlled in self-pollinated flowers to verify their self-compatible phenotypes.The linkage disequilibrium association between alleles at the S-locus and linked markers at the end of the sixth linkage group was not significant(P>0.05),except with the closest markers suggesting the absence of a signature of negative frequency dependent selection at the S-locus.Analysis of SFB1 and SFB2 protein sequences allowed identifying the absence of some variable and hypervariable domains and the presence of additionalα-helices at the C-termini.Molecular and evolutionary analysis of SFB nucleotide sequences showed a signature of purifying selection in SFB2,while the SFB1 seemed to evolve neutrally.Thus,our results show that the SFB2 allele diversified after P.persica and P.dulcis(almond)divergence,a period which is characterized by an important bottleneck,while SFB1 diversified at a transition time between the bottleneck and population expansion.

Compatibility and complementarity of indigenous and scientific knowledge of wild plants in the highlands of southwest Saudi Arabia

This study presents a survey of wild plants commonly used by local inhabitants in the highlands of southwest Saudi Arabia. Based upon literature review, direct observation of local inhabitants, and questionnaire interviews, 36 plant species were assessed and given scores according to their use. The gaps between scientific and indigenous knowl- edge on the use of plants were estimated using a ＂compatibility ratio＂. The score values were estimated based on seven different use categories of ecosystem services, including food, forage, medicine, wood, beekeeping, research, and education. Additional structural categories include source of materials, shade, hedges, ornamental plantings, and soil stabilization. There are discrepancies between indigenous knowledge （IK） and scien- tific knowledge （SK） but in most cases, SK of the species supports the IK and plant users preference. The results also provide information that challenges assumptions about the consistency of IK with SK. Our study highlights the importance of understanding the cultural context and uses of wild plants. Biodiversity-based knowledge holds promise for contributing to sustainable use of wild plant resources and related traditions. The success of such endeavours depends on the compatibility and complementarity of indigenous and scientific knowledge.

The Electromagnetic Compatibility and Distribution of Antenna System

The mathematical model of electromagnetic compatibility and the distribution of aircraft antenna system have been investigated. The solutions of the antenna gain and electromagnetic interference margin in the regions of low frequency, resonance and high frequency were discussed. By using the basic analytical method of the EMI margin the distributed antenna system can be determined. The main program flow chart of distributed antenna design were given, and illustrated with examples of the microstrip antennas.

Research on the stability and compatibility of the cementitious materials of Baosteel steel slag fine powder

The application technology using Baosteel steel slag powder as an admixture of concrete is the developmental direction of steel slag recycling treatment and utilization, which fully reflects the basic features and good compatibility of the over-calcined clinker of steel slag resources. It is beneficial to fully exploit the water hardening characteristic and potential activity of steel slag, to reduce and control the unstable factors, such as free calcium oxide and magnesium oxide, and to realize high value-added applications and explore new application fields.

Experimental Study on Analgesia and Hemostasis of Paris polyphylla,Scutellaria baicalensis and Their Compatibility

[Objectives]The analgesic and hemostatic effects of Paris polyphylla,Scutellaria baicalensis,and their compatibility were studied.[Methods](i)In the experiment on the writhing of mice induced by acetic acid,60 Kunming SPF mice were randomly selected,and were randomly divided into 6 groups according to the male-to-female ratio of 1∶1,including blank control group,P.polyphylla group,S.baicalensis group,and three P.polyphylla and S.baicalensis compatibility groups(with the ratio of 1∶2,1∶1 and 1∶2).There were 10 mice in each group.In the experimental groups,the mice were given 1 g/mL Chinese medicine extract according to a dose of 20 mL/kg.In the control group,the mice were given 0.9%normal saline in equal volumes.Gavage was performed one time every 24 h and lasted for 14 d.1 h after the gavage on the 14th day,they were given 0.5%glacial acetic acid solution via intraperitoneal injection.(ii)In the hot plate experiment,60 Kunming SPF mice were selected,and the ratio of male to female,grouping,administration and gavage were the same as those of the glacial acetic acid-induced writhing experiment.Gavage was lasted for 14 d.1 h after the gavage on the 14th day,the mice were placed on a hot plate apparatus at(55±0.5)℃,and the time of licking hindfoot was measured.(iii)The hemostatic effect was explored through three experimental methods of tail hemostasis,femoral artery hemostasis and liver hemostasis.60 Kunming SPF mice were taken in each of the three experiments,and the male-female ratio and grouping were the same as above.The powder was covered on the surface of the wound sites,and the bleeding was observed.The hemostatic time was recorded,and the hemostatic time was recorded as 3 min if it exceeded 3 min.[Results](i)In the acetic acid-induced writhing experiment,compared with the blank control group,the pain of mice in the experimental groups was inhibited.Among them,P.polyphylla group,S.baicalensis group,compatibility 1∶2 group,compatibility 1∶1 group,and compatibility 2∶1 group had significant effects(P<0.05),and the inhibition rate of writhing was 20.43%,28.32%,52.30%,32.79%,and 39.02%,respectively.The analgesic effect of the compatibility 1∶2 group was the most obvious.(ii)In the hot plate experiment,compared with the blank control group,the experimental groups had analgesic effect.Among them,P.polyphylla group,S.baicalensis group,compatibility 1∶2 group,compatibility 1∶1 group,and compatibility 2∶1 group had significant effects(P<0.05),and the increase rate of pain threshold was 29.17%,47.83%,61.54%,and 50.61%,and 53.83%,respectively.The analgesic effect of the compatibility 2∶1 group was the most significant.(iii)In the hemostatic experiment,there was a significant difference in hemostatic time between the compatibility 1∶2 group and the blank control group,P.polyphylla group,and S.baicalensis group(P<0.05).The hemostatic effect of the compatibility 1∶2 group was the best.[Conclusions]P.polyphylla,S.baicalensis,and its compatibility had good analgesic and hemostatic effects,and the best compatibility ratio was 1∶2.