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The Influence of Price Discrimination from Airports on the Route Development Behavior of Airlines
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作者 Daniel Schnitzler 《Journal of Civil Engineering and Architecture》 2024年第1期17-29,共13页
Given the prominence and magnitude of airport incentive schemes,it is surprising that literature hitherto remains silent as to their effectiveness.In this paper,the relationship between airport incentive schemes and t... Given the prominence and magnitude of airport incentive schemes,it is surprising that literature hitherto remains silent as to their effectiveness.In this paper,the relationship between airport incentive schemes and the route development behavior of airlines is analyzed.Because of rare and often controversial findings in the extant literature regarding relevant influencing variables for attracting airlines at an airport,expert interviews are used as a complement to formulate testable hypotheses in this regard.A fixed effects regression model is used to test the hypotheses with a dataset that covers all seat capacity offered at the 22 largest German commercial airports in the week 46 from 2004 to 2011.It is found that incentives from primary choice,as well as secondary choice airports,have a significant influence on Low Cost Carriers.Furthermore,Low Cost Carriers,in general,do not leave any of both types of airports when the incentives cease.In the case of Network Carriers,no case is found where one joins a primary choice airport and receives an incentive.Insufficient data between Network Carriers and secondary choice airports in the time when incentives have ceased means that no statement can be given. 展开更多
关键词 AIRLINE rout development price discrimination
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The HD-Zip transcription factor LcATHB15 is involved in litchi seed development by promoting the expression of the splicing regulator LcSR45
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作者 Hanhan Xie Fei Wang +3 位作者 Zidi He Zhijian Liang Jianguo Li Minglei Zhao 《Horticultural Plant Journal》 SCIE CAS CSCD 2024年第6期1463-1466,共4页
Litchi (Litchi chinensis Sonn.) is a well-known tropical and subtropical woody fruit that originated from southern China (Wei et al.,2017;Hu et al.,2022).Based on the development of the embryo,litchi varieties can be ... Litchi (Litchi chinensis Sonn.) is a well-known tropical and subtropical woody fruit that originated from southern China (Wei et al.,2017;Hu et al.,2022).Based on the development of the embryo,litchi varieties can be divided into three distinct groups:large-seeded cultivars,small (abortive)-seeded cultivars and partial abortive-seeded cultivars.Seedless or the reduction in seed size due to embryo abortion is a desirable trait in fruit trees as it directly influences the texture and economic value of fleshy fruits,making small (abortive)-seeded litchi cultivars the most preferred.However,in current production practices,there is no efficient method available to induce or promote high seed abortion in litchi fruit.Therefore,understanding the stenospermy mechanisms of litchi seed development is of great significance for improving agricultural practices and managing genetic resources. 展开更多
关键词 CULTIVAR originated development
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Distribution,Origin and Development Status of Underground Brine Resource along the Coast of Laizhou Bay,Shandong Province
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作者 LI Shouping MENG Ye 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2014年第S1期222-222,共1页
The underground brine resource along the coast of Laizhou Bay is the world’s rare shallow underground brine resource,which occurs in the Laizhou city in the east,and extends to the coastal area of the Binzhou city in
关键词 underground brine resource distribution origin development status BROMIDE
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Development and application of magnesium alloy parts for automotive OEMs:A review 被引量:16
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作者 Bo Liu Jian Yang +3 位作者 Xiaoyu Zhang Qin Yang Jinsheng Zhang Xiaoqing Li 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第1期15-47,共33页
China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressivel... China is currently vigorously implementing the“energy conservation and emission reduction”and“dual carbon”strategies.As the most resource-advantaged light metal material in China,Magnesium(Mg)alloy is progressively expanding its application in automobile,rail transportation,aerospace,medical,and electronic products.Chongqing University,Shanghai Jiaotong University,and Australian National University have conducted extensive research on the preparation,properties,and processes of Mg alloys.In the past 20 years,the proportion of Mg alloy in the automotive industry has gradually expanded,whereas currently the design and development of Mg alloy parts for automobiles has rarely been reported.Thus,the application models and typical parts cases of Mg alloy are summarized mainly from the four systems of the whole vehicle(body system,chassis system,powertrain system,interior,and exterior system).Subsequently,two actual original equipment manufacturers(OEM)cases are used to introduce the development logic of reliable die-cast Mg alloy,including forward design,formability analysis,process design analysis,structural redesign,manufacturing,and testing,aiming to share the methods,processes,and focus of attention of automotive OEMs for developing Mg alloy parts to enhance the confidence and motivation of applying Mg alloy in automotive field.Eventually,the multiple challenges faced by Mg alloy materials are sorted out and how to face these challenges are discussed.National policies and regulations,environmental protection and energy saving,and consumer demand will continue to promote the application of Mg. 展开更多
关键词 Magnesium alloy original equipment manufacturer Automotive application development process
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Study on the Rights to Subsistence and Development with Reference to the Origin of the Universal Declaration of Human Rights
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作者 李君如 Hu Liang(译) 《The Journal of Human Rights》 2018年第5期461-464,共4页
I.The History of the Drafting of the Universal Declaration of Human Rights:the Position and Role of the UN Economic and Social Council and the General Assembly of the United Nations should not be Ignored The reason fo... I.The History of the Drafting of the Universal Declaration of Human Rights:the Position and Role of the UN Economic and Social Council and the General Assembly of the United Nations should not be Ignored The reason for me to use the term "source"in the discussion on the right to subsistence 展开更多
关键词 UN Study on the Rights to Subsistence and development with Reference to the origin of the Universal Declaration of Human Rights
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Traditional Chinese Medicine and Standardization——Origin and development of TCM 被引量:2
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作者 Xu Chunbo professor,vice secretary-general of World Federation of Chinese Medicine Societies. 《China Standardization》 2011年第1期24-28,共5页
Traditional Chinese Medicine (TCM) is the medical science based on theories and practicing experience of traditional Chinese medicine to study transferring principles of health and sickness,as well as prevention, diag... Traditional Chinese Medicine (TCM) is the medical science based on theories and practicing experience of traditional Chinese medicine to study transferring principles of health and sickness,as well as prevention, diagnosis,treatment,rehabilitation and healthcare.TCM is marked with its long history of development,integrated theory system and abundant practicing experience. 展开更多
关键词 origin and development of TCM Traditional Chinese Medicine and Standardization St
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Nomenclature Origin and Development of Bi Syndrome Prescriptions
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作者 Lamei ZHOU Yuanyuan DING Donglin HAO 《Medicinal Plant》 CAS 2019年第6期10-14,共5页
More than 40 medical history and classical medical literature on the nomenclature of Bi syndrome were systematically arranged,induced and analyzed,the prescriptions named after the medicine include RHIZOMA ET RADIX NO... More than 40 medical history and classical medical literature on the nomenclature of Bi syndrome were systematically arranged,induced and analyzed,the prescriptions named after the medicine include RHIZOMA ET RADIX NOTOPTERYGII,os tigris,RADIX ASTRAGALI,RADIX SAPOSHNIKOVIAE,Prepared common monkshood daughter root,doubleteeth pubescent angelica root,RADIX ANGELICAE SINENSIS,frankincense,RADIX STEPHANIAE TETRANDRAE,RADIX ACHYRANTHIS BIDENTATAE,myrrh,RADIX ACONITI、RADIX DIPSACI,RHIZOMA GASTRODIAE,ginseng root,HERBA DENDROBII,CORNU SAIGAE TATARICAE,RADIX MORINDAE OFFICINALIS,PORIA,SEMEN COICIS,poison yam,and so on.It basically reflected the ancient and modern treatment of Bi syndrome in traditional Chinese medicine named after the formula. 展开更多
关键词 BI SYNDROME Prescription NOMENCLATURE origin and development
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The Formation Background and Scientific Connotation of the Concept of Shared Development
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作者 WANG Yi QIN Shusheng 《Journal of Philosophy Study》 2020年第1期16-21,共6页
Since the 18th National Congress of the Communist Party of China,the Party Central Committee with President Xi Jinping has put forward a new development concept of innovation,coordination,green,openness,and sharing ba... Since the 18th National Congress of the Communist Party of China,the Party Central Committee with President Xi Jinping has put forward a new development concept of innovation,coordination,green,openness,and sharing based on profound insight into the basic characteristics of the new development stage.The party scientific grasps the essential requirements and development direction of socialism with Chinese characteristics,and continuously deepens understanding of the laws of economic and social development.Starting from three aspects of the times background,theoretical origin,and scientific connotation,the party aims to deeply understand the specific content and profound implication of the shared development concept in the new era. 展开更多
关键词 SHARED development theORETICAL origin SCIENTIFIC CONNOTATION
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Development and psychometric evaluation of the Ethical Behavior for Thai Nurses Scale
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作者 Pisamai Orathai Wonnapha Prapaipanich +1 位作者 Manee Arpanantikul Supanee Senadisai 《Frontiers of Nursing》 2022年第3期275-284,共10页
Background:Ethical problems in the nursing profession are mostly found in the undesirable ethical behavior(EBE)of nurses.If there is no concern about these problems,it may negatively affect the quality of nursing care... Background:Ethical problems in the nursing profession are mostly found in the undesirable ethical behavior(EBE)of nurses.If there is no concern about these problems,it may negatively affect the quality of nursing care,patients’safety,and trust in the nursing profession.In assessing nurses’EBE,it is important to develop an instrument that reflects the actual EBE of nurses.Objectives:To develop and evaluate the psychometric properties of the Ethical Behavior for Thai Nurses Scale(EBTNS).Methods:The construct definition,5 sub-constructs,43 items,and the hypothesized model were synthesized and generated from a comprehensive literature review and existing research instruments by using document analysis.The EBTNS was verified for content validity by 4 experts.Of the 43 items,37 items were retained for psychometric testing.The construct validity was tested by using second-order confirmatory factor analysis(CFA).The EBTNS was tested on 1500 professional nurses working at tertiary,secondary,and primary hospitals in 6 regions(the central,northern,northeast,eastern,western,and southern)of Thailand.Proportional quota sampling was applied to recruit participants.Results:The hypothesized model fitted the empirical data.All 37 first-order indicators and 5 second-order sub-constructs showed significantly standardized factor loadings and effect sizes.The standardized factor loadings of 37 first-order indicators ranged from 0.58 to 0.89,and the construct reliabilities were moderate to substantial(R2=0.34-0.79).The 5 second-order sub-constructs displayed the standardized effect sizes,ranging from 0.81 to 0.96,and accounted for 65%-96%of the total explained variance.In addition,the construct validity was supported by convergent validity and discriminant validity.It also satisfied Cronbach’s alpha coefficients of 5 sub-constructs from 0.87 to 0.94,and a full scale was 0.97.Conclusions:The psychometric properties of the EBTNS are acceptable.This instrument has the potential to be used for evaluating and monitoring to prevent ethical problems of Thai nurses. 展开更多
关键词 construct validity convergent validity discriminant validity ETHICS nurses scale development
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A Summary about the Formation and Development of"Alcohol Injury"Theory
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作者 Gao Li Dong-Xin Tang +1 位作者 Feng-Xi Long Zhu Yang 《Food Therapy and Health Care》 2019年第1期16-21,共6页
The number of people who are sickened by alcohol is rising every year in China,and Traditional Chinese Medicine(TCM)has a long history and remarkable therapeutic effect on the treatment of"Alcohol Injury"dis... The number of people who are sickened by alcohol is rising every year in China,and Traditional Chinese Medicine(TCM)has a long history and remarkable therapeutic effect on the treatment of"Alcohol Injury"diseases.Therefore,it is of great practical significance to study the theory of"Alcohol Injury".This paper expounds the historical origin,treatment prescription and related diseases of the theory of"Alcohol Injury". 展开更多
关键词 ALCOHOL INJURY theory HISTORICAL origin development
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Integrating the valence theory and the norm activation theory to understand consumers’ e-waste recycling intention
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作者 Hong Thi Thu Nguyen 《Chinese Journal of Population,Resources and Environment》 2023年第1期26-36,共11页
Electrical and electronic waste(e-waste)is a growing challenge,matching the widespread boom in the use of information and communication technology.Opposite to an alarming increasing amount of e-waste,a low rate of con... Electrical and electronic waste(e-waste)is a growing challenge,matching the widespread boom in the use of information and communication technology.Opposite to an alarming increasing amount of e-waste,a low rate of consumer engagement in ensuring the proper disposal of such materials intensifies the pressure on the exist‐ing e-waste crisis.To deal with this thorny problem,it is of great interest to grasp consumers’disposal and re‐cycling behavioral intentions.Therefore,this study attempts to understand complementary perspectives around consumers’e-waste recycling intention based on the integration of the valence theory and the norm activation theory.Four data mining models using classification and prediction-based algorithms,namely Chi squared automatic interaction detector(CHAID),Neural network,Discriminant analysis,and Quick,unbiased,efficient statistical tree(QUEST),were employed to analyze a set of the 398 data collected in Vietnam.The re‐sults revealed that the social support value is by far the most critical predictor,followed by the utilitarian value,task difficulty,and monetary risk.It is also noteworthy that the awareness of consequences,education background,the ascription of responsibility,and age were also ranked as critical affecting factors.The lowest influential predictors found in this study were income and gender.In addition,a comparison was made in terms of the classification performance of the four utilized data mining techniques.Based on several evalua‐tion measurements(confusion matrix,accuracy,precision,recall,specificity,F-measure,ROC curve,and AUC),the aggregated results suggested that CHAID and Neural network performed the best.The findings of this research are expected to assist policymakers and future researchers in updating all information surround‐ing consumer behavioral intention-related topics focusing on e-waste.Furthermore,the adoption of data min‐ing algorithms for prediction is another insight of this study,which may shed the light on data mining applica‐tions in such environmental studies in the future. 展开更多
关键词 CHAID Discriminant analysis E-waste recycling intention Neural network Norm activation theory QUEST Sustainable development goals Valence theory
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Tectonic development of subtle faults and exploration in mature areas in Bohai Sea,East China 被引量:2
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作者 XUE Yongan LYU Dingyou +2 位作者 HU Zhiwei HUANG Jiangbo REN Jian 《Petroleum Exploration and Development》 CSCD 2021年第2期269-285,共17页
Based on the theory of structural analysis,the characteristics and structural patterns of subtle faults are studied using 3D seismic data of the Bohai Sea to analyze the development process and origin of the subtle fa... Based on the theory of structural analysis,the characteristics and structural patterns of subtle faults are studied using 3D seismic data of the Bohai Sea to analyze the development process and origin of the subtle faults.A method of identifying subtle faults is proposed,forming a complete system for analyzing origins of subtle faults in the Bohai Sea.The complex strike-slip fault patterns under the strike-slip and extension stress background,diverse formation rocks,and strong neotectonic movement are the reasons for the development of subtle faults.According to the tectonic origin and development location,the subtle faults in Bohai Sea can be divided into 12 types in the three categories of strike slip dominant,extension dominant and strike slip and extension composite,and the different types of subtle faults occur in different regions of the Bohai Sea.Unreasonable variation of sedimentary stratum thickness,inherited distortion or even abrupt change of stratum occurrence,zonation of plane fault combination and the variation of oil-water system in the same structure with no-lithologic change are the important signs for identifying subtle faults in Bohai Sea.The subtle faults greatly enlarge the size of the structural trap groups,and areas with dense subtle faults are often active area of hydrocarbon migration and accumulation and favorable exploration zones,which have strong control on the hydrocarbon accumulation.The identification method for subtle faults has guided the exploration in the mature areas of Bohai Sea effectively,with a number of large and medium oil and gas fields discovered,such as Bozhong 29-6 and Penglai 20-2. 展开更多
关键词 subtle fault tectonic origin tectonic development characteristics hydrocarbon accumulation control Bohai Sea
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Mastering the craft:Creating an insightful and widely-cited literature review
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作者 Shengwen Calvin Li 《World Journal of Stem Cells》 SCIE 2023年第8期781-786,共6页
The art of constructing an insightful literature review manuscript has witnessed an exemplar in the work of Oz et al(2023),wherein concept progression harmoniously merges with figures and tables.Reflecting on retrospe... The art of constructing an insightful literature review manuscript has witnessed an exemplar in the work of Oz et al(2023),wherein concept progression harmoniously merges with figures and tables.Reflecting on retrospective data science,it is evident that well-cited articles can wield a transformative influence on the Journal Citation Reports Impact Factor score,as exemplified by Robert Weinberg’s landmark on cancer(Hanahan and Weinberg,2011).Here,we aim to spotlight a commendable contribution by Tuba Oz,Ajeet Kaushik,and Małgorzata Kujawska in this issue while pivoting towards identifying the hallmarks of a subpar literature review-elements that hinder rather than promote advancement.The hurdles and roadblocks encountered within subpar literature reviews are multifold.Anticipation of emerging trends,identification of challenges,and exploration of solutions remain conspicuously absent.Original Contributions fail to surface amidst the vast sea of pre-existing literature,with noticeable gaps amplified by the lack of illustrative figures and tables.The manuscript,at times,assumes a skeletal form,reflecting an attempt to accommodate an excess of references,leading to convoluted sentences laden with citations.In contrast,a potent solution lies in adopting a comprehensive approach.A nuanced and critical evaluation of sources can culminate in a robust discussion,surpassing the mere summarization of conclusions drawn by others.This approach,often dismissed,holds the potential to elevate clarity,coherence,and logical flow,ultimately inviting engaged readership and coveted citations.The critical necessity of integrating visionary insights is underscored and achieved through a rigorous analysis of pivotal concepts and innovative ideas.Examples can be harnessed to elucidate the application of these solutions.We advocate a paradigm shift,urging literature review writers to embrace the readers’perspective.A literature review’s purpose extends beyond providing a comprehensive panorama;it should illuminate avenues for concept development within a specific field of interest.By achieving this balance,literature reviews stand to captivate a devoted readership,paving the way for manuscripts that are both widely read and frequently cited.The pathway forward requires a fusion of astute analysis and visionary insights,shaping the future of literature review composition. 展开更多
关键词 Literature review Concept progression Data science Journal Citation Reports Impact Factor original contributions Comprehensive approach Clarity and coherence Visionary insights Reader engagement Concept development
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The Ups and Downs of Yiddish Language
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作者 董菲菲 《海外英语》 2014年第4X期157-159,共3页
The Yiddish language originated in Ashkenazi culture and is spoken by Ashkenai Jewish who are thought to be the descendants of Rhineland Jews. For years, it was carried to many parts of the world with the migration of... The Yiddish language originated in Ashkenazi culture and is spoken by Ashkenai Jewish who are thought to be the descendants of Rhineland Jews. For years, it was carried to many parts of the world with the migration of these Ashkenazi Jewish and a real version of ups and downs of the people. It was once considered as a dialect of German rather than an independent language, which many scholars of Ashkenazi Jewish origin managed to get rid of. It aims to give a brief introduction to this language and try to trace back its origin and development so as to bring a brief senario of the Ashkenazi Jewish's striving for their identity. Having read and study literatures about this language, a conclusion can be reached that Yiddish language means"the mother tongue of Jewish people"which reflects Jewish cultural life and finally prove its value that it deserved in fields of linguistics and literature through centuries-long wax and wane. 展开更多
关键词 Yiddish ASHKENAZI Jewish origin development VALUE
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Discrimination of clonal origin patterns for molecular pathological diagnosis of RHCC/MHCC
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作者 Wenming Cong Mengchao Wu 《Cancer Biology & Medicine》 SCIE CAS CSCD 2018年第S01期16-16,共1页
Objective:The high post-operative recurrence of hepatocellular carcinoma(RHCC)and multinodular hepatocellular carcinoma(MHCC)seriously limit the surgical efficacy of HCC.Theoretically,RHCC/MHCC arise from either resid... Objective:The high post-operative recurrence of hepatocellular carcinoma(RHCC)and multinodular hepatocellular carcinoma(MHCC)seriously limit the surgical efficacy of HCC.Theoretically,RHCC/MHCC arise from either residual tumor cells or novel clone-derived tumor cells which have a great impact on designing personalized therapies and the evaluation of clinical long-term outcome. 展开更多
关键词 discrimination CLONAL origin
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Human embryonic stem cells as an in vitro model for studying developmental origins of type 2 diabetes
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作者 Andy Chun-Hang Chen Kai Fai Lee +1 位作者 William Shu Biu Yeung Yin Lau Lee 《World Journal of Stem Cells》 SCIE CAS 2020年第8期761-775,共15页
The developmental origins of health and diseases(DOHaD)is a concept stating that adverse intrauterine environments contribute to the health risks of offspring.Since the theory emerged more than 30 years ago,many epide... The developmental origins of health and diseases(DOHaD)is a concept stating that adverse intrauterine environments contribute to the health risks of offspring.Since the theory emerged more than 30 years ago,many epidemiological and animal studies have confirmed that in utero exposure to environmental insults,including hyperglycemia and chemicals,increased the risk of developing noncommunicable diseases(NCDs).These NCDs include metabolic syndrome,type 2 diabetes,and complications such as diabetic cardiomyopathy.Studying the effects of different environmental insults on early embryo development would aid in understanding the underlying mechanisms by which these insults promote NCD development.Embryonic stem cells(ESCs)have also been utilized by researchers to study the DOHaD.ESCs have pluripotent characteristics and can be differentiated into almost every cell lineage;therefore,they are excellent in vitro models for studying early developmental events.More importantly,human ESCs(hESCs)are the best alternative to human embryos for research because of ethical concerns.In this review,we will discuss different maternal conditions associated with DOHaD,focusing on the complications of maternal diabetes.Next,we will review the differentiation protocols developed to generate different cell lineages from hESCs.Additionally,we will review how hESCs are utilized as a model for research into the DOHaD.The effects of environmental insults on hESC differentiation and the possible involvement of epigenetic regulation will be discussed. 展开更多
关键词 development origins of health and diseases Maternal diabetes Environmental insults Type 2 diabetes Human embryonic stem cells EPIGENETICS
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"Love" Is the Origin of All Dances
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作者 Ziqiao Wang 《Review of Educational Theory》 2018年第4期134-136,共3页
The art of dance comes from life;it is a reflection and portrayal of life. It is based on people's ambitions for a better life and carries beautiful wishes. These beautiful roots are ultimately derived from "... The art of dance comes from life;it is a reflection and portrayal of life. It is based on people's ambitions for a better life and carries beautiful wishes. These beautiful roots are ultimately derived from "love", in the dance based on the image of people. Dance art expresses the love between people, the love of human and nature, the love of human and society;in the dance works based on the object, the intrinsic connection between nature and the natural world is also reflected. This paper expounds the cognition of dance in terms of children's dance enlightenment, limb development, aesthetic education, etc., and promotes the continuous development of the dance cause, cultivates more outstanding dancers, and creates more excellent dance works. 展开更多
关键词 DANCE origin DANCE ENLIGHTENMENT LIMB development DANCE image SHAPING AEStheTIC education
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Legal Origin, Endowment and Financial Development
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作者 张世雯 《海外英语》 2016年第20期230-232,共3页
Since the rise of the economic and financial development theory, around economic and financial development of the determinants and what financial arrangements for promoting economic growth and other issues, thus resul... Since the rise of the economic and financial development theory, around economic and financial development of the determinants and what financial arrangements for promoting economic growth and other issues, thus resulted in a variety of important theoretical debate. This paper will Define what is meant by key terms such as legal tradition and endowment, explain the channels through which legal tradition and endowment affect financial development through talking about the relationship between legal origin, initial in endowment and financial development. By comparing different legal traditions or the"Origins"between the The Continental Law System and Common Law System, a comprehensive analysis of the effects of different origin of law on the financial and economic development. 展开更多
关键词 LEGAL FINANCIAL economic development legal origin ENDOWMENT
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The Sociology of Language——the Origin of Chinese
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作者 况玥 《海外英语》 2020年第2期85-86,98,共3页
Languages come from lives of people and characters are the conventional text symbol system in society.There are thou⁃sands of languages around the world,only less than half of which own the corresponding characters,an... Languages come from lives of people and characters are the conventional text symbol system in society.There are thou⁃sands of languages around the world,only less than half of which own the corresponding characters,and Chinese is one of the lan⁃guages that has the corresponding characters.Chinese characters are not only still in use today but also are the oldest and best pre⁃served characters all over the world,which because of the close connection with Han nationality and Han culture.The paper ex⁃plores the origin of Chinese pronunciation,the origin of Chinese writing,the development of Chinese,and the connection between Chinese and Han culture.Also,it is important and significant for people to know how to protect our own languages. 展开更多
关键词 origin Chinese language Chinese pronunciation Chinese Pinyin Chinese Writing Chinese language development Chi⁃nese language protection
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Embracing oligodendrocyte diversity in the context of perinatal injury 被引量:1
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作者 Jessie Newville Lauren L.Jantzie Lee Anna Cunningham 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第10期1575-1585,共11页
Emerging evidence is fueling a new appreciation of oligodendrocyte diversity that is overturning the traditional view that oligodendrocytes are a homogenous cell population.Oligodendrocytes of distinct origins,maturat... Emerging evidence is fueling a new appreciation of oligodendrocyte diversity that is overturning the traditional view that oligodendrocytes are a homogenous cell population.Oligodendrocytes of distinct origins,maturational stages,and regional locations may differ in their functional capacity or susceptibility to injury.One of the most unique qualities of the oligodendrocyte is its ability to produce myelin.Myelin abnormalities have been ascribed to a remarkable array of perinatal brain injuries,with concomitant oligodendrocyte dysregulation.Within this review,we discuss new insights into the diversity of the oligodendrocyte lineage and highlight their relevance in paradigms of perinatal brain injury.Future therapeutic development will be informed by comprehensive knowledge of oligodendrocyte pathophysiology that considers the particular facets of heterogeneity that this lineage exhibits. 展开更多
关键词 oligodendrogenesis oligodendrocyte progenitor cell myelination central nervous system development ontogenetic origin white matter white matter injury preterm birth glia macroglia
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