Objective:To determine the circadian influence on sound sensitivity produced by temporal hearing deprivation in healthy normal human subjects.Design:Participants underwent bilateral earplugging before completion of an...Objective:To determine the circadian influence on sound sensitivity produced by temporal hearing deprivation in healthy normal human subjects.Design:Participants underwent bilateral earplugging before completion of anthropometry,the author's developed questionnaire,the Hamilton Anxiety and Depression Inventory,pure tone audiometry(PTA),stapedial reflex thresholds(SRT),distortion products otoacoustic emissions input/output(DPOAE-I/O),and uncomfortable loudness levels(ULLs).Afterward,the participants were randomly divided into group A,starting at 8:00 a.m.and finishing at 8:00 p.m.,and group B,starting at 4:00 p.m.and ending at 4:00 a.m.Serum cortisol levels and audiological test results were obtained at the beginning and end of the session and 24-h free urinary cortisol levels were measured.Study sample:Thirty healthy volunteers.Results:PTA was 2.68 and 3.33 dB HL in groups A and B,respectively,with no statistical difference between them.ULLs were significantly lower in group A compared to group B,with an average of 8.1 dB SPL in group A and 3.3 dB SPL in group B(p<0.0001).A SRT shift was observed in group A,with no difference in group B,and a night shift in DPOAE-I/O in group B.Conclusions:Reduced loudness tolerance is demonstrated during daytime hearing deprivation in contrast to nighttime;this may be due to increased central gain in the awake cortex.展开更多
Objective: To verify the efficacy of cochlear implantation in a patient with Arnold-Chiari syndrome. Design: Review of a medical chart from a patient with Arnold-Chiari syndrome that underwent to cochlear implant surg...Objective: To verify the efficacy of cochlear implantation in a patient with Arnold-Chiari syndrome. Design: Review of a medical chart from a patient with Arnold-Chiari syndrome that underwent to cochlear implant surgery. Case report: A 6 year-old female, with meningomyelocele and congenital hydrocephalus, deaf in the past 3 years, after meningitis. At that time, she used oral language with adequate speech development. Tone audiometry revealed bilateral profound sensorineural hearing loss. The MRI was compatible with the Arnold-Chiari syndrome. Cochlear implantation was performed on the left ear with MED-EL? Implant (model SONATATi100). Currently, the child is 12 year-old, performs speech therapy three times a week, with good hearing and language development. Conclusion: Despite the presence of Arnold-Chiari syndrome (Chiari type II) with neurological disorders and with ventriculoperitoneal shunt, patient had good hearing results after cochlear implant surgery.展开更多
目的探讨个性化切迹音乐对主观性耳鸣的治疗效果,以及耳鸣频率、相关听力学频率特性对治疗效果的影响。方法选取纯音听阈在70d B HL以内的主观性耳鸣患者20名,接受1个月的个性化切迹音乐治疗。以耳鸣致残量表(tinnitus handicap invento...目的探讨个性化切迹音乐对主观性耳鸣的治疗效果,以及耳鸣频率、相关听力学频率特性对治疗效果的影响。方法选取纯音听阈在70d B HL以内的主观性耳鸣患者20名,接受1个月的个性化切迹音乐治疗。以耳鸣致残量表(tinnitus handicap inventory,THI)评价患者治疗前后变化。结果经过个性化切迹音乐治疗后,患者总THI得分明显降低,呈显著差异。治疗有效组中听力损伤患者平均耳鸣频率接近平均边缘频率,两者呈显著相关性;同时,最大听力损伤频率明显高于平均耳鸣频率,存在显著差异。然而,无效组平均耳鸣频率则接近平均最大听力损伤频率,且两者存在显著相关性;另外,无效组平均耳鸣频率明显高于边缘频率,存在显著差异。结论个性化切迹音乐治疗能有效减轻耳鸣带来的困扰,改善主观症状与生活质量。耳鸣频率与相关听力学频率特性之间的关系可能作为反映耳鸣患者中枢机制与预测个性化切迹音乐治疗效果的指标。展开更多
文摘Objective:To determine the circadian influence on sound sensitivity produced by temporal hearing deprivation in healthy normal human subjects.Design:Participants underwent bilateral earplugging before completion of anthropometry,the author's developed questionnaire,the Hamilton Anxiety and Depression Inventory,pure tone audiometry(PTA),stapedial reflex thresholds(SRT),distortion products otoacoustic emissions input/output(DPOAE-I/O),and uncomfortable loudness levels(ULLs).Afterward,the participants were randomly divided into group A,starting at 8:00 a.m.and finishing at 8:00 p.m.,and group B,starting at 4:00 p.m.and ending at 4:00 a.m.Serum cortisol levels and audiological test results were obtained at the beginning and end of the session and 24-h free urinary cortisol levels were measured.Study sample:Thirty healthy volunteers.Results:PTA was 2.68 and 3.33 dB HL in groups A and B,respectively,with no statistical difference between them.ULLs were significantly lower in group A compared to group B,with an average of 8.1 dB SPL in group A and 3.3 dB SPL in group B(p<0.0001).A SRT shift was observed in group A,with no difference in group B,and a night shift in DPOAE-I/O in group B.Conclusions:Reduced loudness tolerance is demonstrated during daytime hearing deprivation in contrast to nighttime;this may be due to increased central gain in the awake cortex.
文摘Objective: To verify the efficacy of cochlear implantation in a patient with Arnold-Chiari syndrome. Design: Review of a medical chart from a patient with Arnold-Chiari syndrome that underwent to cochlear implant surgery. Case report: A 6 year-old female, with meningomyelocele and congenital hydrocephalus, deaf in the past 3 years, after meningitis. At that time, she used oral language with adequate speech development. Tone audiometry revealed bilateral profound sensorineural hearing loss. The MRI was compatible with the Arnold-Chiari syndrome. Cochlear implantation was performed on the left ear with MED-EL? Implant (model SONATATi100). Currently, the child is 12 year-old, performs speech therapy three times a week, with good hearing and language development. Conclusion: Despite the presence of Arnold-Chiari syndrome (Chiari type II) with neurological disorders and with ventriculoperitoneal shunt, patient had good hearing results after cochlear implant surgery.
文摘目的探讨个性化切迹音乐对主观性耳鸣的治疗效果,以及耳鸣频率、相关听力学频率特性对治疗效果的影响。方法选取纯音听阈在70d B HL以内的主观性耳鸣患者20名,接受1个月的个性化切迹音乐治疗。以耳鸣致残量表(tinnitus handicap inventory,THI)评价患者治疗前后变化。结果经过个性化切迹音乐治疗后,患者总THI得分明显降低,呈显著差异。治疗有效组中听力损伤患者平均耳鸣频率接近平均边缘频率,两者呈显著相关性;同时,最大听力损伤频率明显高于平均耳鸣频率,存在显著差异。然而,无效组平均耳鸣频率则接近平均最大听力损伤频率,且两者存在显著相关性;另外,无效组平均耳鸣频率明显高于边缘频率,存在显著差异。结论个性化切迹音乐治疗能有效减轻耳鸣带来的困扰,改善主观症状与生活质量。耳鸣频率与相关听力学频率特性之间的关系可能作为反映耳鸣患者中枢机制与预测个性化切迹音乐治疗效果的指标。
