October 19,2007 Vice Premier Wu Yi,PRC On behalf of Chinese government,I would like to congratulate the 20th Foundation of World Federation of Acupuncture-Moxibustion Societies(WFAS)and International Acupuncture Congr...October 19,2007 Vice Premier Wu Yi,PRC On behalf of Chinese government,I would like to congratulate the 20th Foundation of World Federation of Acupuncture-Moxibustion Societies(WFAS)and International Acupuncture Congress which is to be held in Beijing,China.And also I give my warm welcome and regards to TCM/Acupuncture colleagues all over the world.展开更多
Foreword Since the foundation of P.R.C.,the China's power grid develops with a high rate.By now,grids in all provinces except Xinjiang,Tibet,Hainan and Taiwan are AC/DC interconnected together,forming the structur...Foreword Since the foundation of P.R.C.,the China's power grid develops with a high rate.By now,grids in all provinces except Xinjiang,Tibet,Hainan and Taiwan are AC/DC interconnected together,forming the structure of power grid interconnection in the whole country.展开更多
The prevalence of unwholesome land use practices and population pressure exacerbates soil loss which is worsening the problem of sedimentation of the Kubanni dam. This study was conducted at the Kubanni drainage basin...The prevalence of unwholesome land use practices and population pressure exacerbates soil loss which is worsening the problem of sedimentation of the Kubanni dam. This study was conducted at the Kubanni drainage basin covering a spatial area of 56.7 Km2 in Samaru, Zaria, Nigeria to estimate annual soil loss using the RUSLE model. Satellite images of Landsat OLI for December 2014, 2016, 2018, February, July and November 2022;soil data, rainfall data from 2010 to 2022, and DEM of 30-meter resolution were utilized for the study. All factors of the RUSLE model were calculated for the basin using assembled data. The erosivity (R-factor) was discovered to be 553.437 MJ∙mm∙ha−1∙h−1∙yr−1. The average erodibility (K-factor) value was 0.1 Mg∙h∙h∙ha−1∙MJ−1∙mm−1∙yr−1. The Slope Length and Steepness factor (LS-factor) in the basin ranged between 0% and 13.47%. The Crop Management Factor (C-factor) values were obtained from a rescaling of the NDVI values derived for the study area and ranged from 0.26 to 0.55. Support practice (P-factors) were computed from the prevalent tillage practice in the basin and ranged from 0.27 to 0.40. The soil loss amount for the Kubanni basin was found to be 28441.482 tons∙ha−1∙yr−1, while the annual soil loss for the entire Kubanni drainage basin was found to be 49780.257 tons∙yr−1. The study has demonstrated the viability of coupling RUSLE model and Remote Sensing and Geographic Information System (GIS) techniques for the estimation of soil loss in the Kubanni drainage basin.展开更多
Missense mutations in the leucine rich repeat kinase 2 (LRRK2) gene are the leading genetic cause of autosomal dominant familial Parkinson’s disease. We previously reported that two mutations within the ROC domain, n...Missense mutations in the leucine rich repeat kinase 2 (LRRK2) gene are the leading genetic cause of autosomal dominant familial Parkinson’s disease. We previously reported that two mutations within the ROC domain, namely R1441C and A1442P, exhibit increased protein degradation leading to lowered steady state LRRK2 protein levels in HEK293 cells. More recently, the common WD40 domain LRRK2 haplotype, Met2397, which is a risk factor for Crohn’s disease, has been shown to lower steady state protein levels in HEK293 cells. In view of recent evidence implicating LRRK2 and inflamemation in PD, we investigated the effects of Met2397 on LRRK2 expression, and compared them to the Thr2397 variant and other LRRK2 mutants. In this study, we transfected HEK293 cells with plasmid constructs encoding the different LRRK2 variants, and analyzed the resulting protein levels by Western blot and flow cytometry. Here we found that both the Met2397 and Thr2397 haplotypes yield similar levels of LRRK2 protein expression and do not appear to impact cell viability in HEK293 cells, compared to other LRRK mutants. Thus, we have concluded that the Met2397 haplotype is unlikely to play a role in LRRK2 mediated or idiopathic PD.展开更多
An effective rapid assessment technique, called ＂P25 Scoring Method＂, has been developed and tested on 26 different case studies recently, in order to predict the collapse vulnerability of the R/C buildings. After a...An effective rapid assessment technique, called ＂P25 Scoring Method＂, has been developed and tested on 26 different case studies recently, in order to predict the collapse vulnerability of the R/C buildings. After a short description of the approach, the study presents the sensitivity study of the method to the selected structural parameters by considering incremental deviation of the final scores from the base model. Further, the methodology was applied to an additional 100 damaged buildings in order to check the reliability of the method and some necessary modifications have been applied to the algorithm after considering this larger database. The evaluation of the results has been interpreted as a beneficial guidance for local authorities. The risk bands are defined according to the final scores and the effect of changing the band-width has also been studied through a safe but an economical procedure. A satisfactory correlation of the method with real damage states is obtained and a ready-to-use methodology has been introduced for future studies.展开更多
文摘October 19,2007 Vice Premier Wu Yi,PRC On behalf of Chinese government,I would like to congratulate the 20th Foundation of World Federation of Acupuncture-Moxibustion Societies(WFAS)and International Acupuncture Congress which is to be held in Beijing,China.And also I give my warm welcome and regards to TCM/Acupuncture colleagues all over the world.
文摘Foreword Since the foundation of P.R.C.,the China's power grid develops with a high rate.By now,grids in all provinces except Xinjiang,Tibet,Hainan and Taiwan are AC/DC interconnected together,forming the structure of power grid interconnection in the whole country.
文摘The prevalence of unwholesome land use practices and population pressure exacerbates soil loss which is worsening the problem of sedimentation of the Kubanni dam. This study was conducted at the Kubanni drainage basin covering a spatial area of 56.7 Km2 in Samaru, Zaria, Nigeria to estimate annual soil loss using the RUSLE model. Satellite images of Landsat OLI for December 2014, 2016, 2018, February, July and November 2022;soil data, rainfall data from 2010 to 2022, and DEM of 30-meter resolution were utilized for the study. All factors of the RUSLE model were calculated for the basin using assembled data. The erosivity (R-factor) was discovered to be 553.437 MJ∙mm∙ha−1∙h−1∙yr−1. The average erodibility (K-factor) value was 0.1 Mg∙h∙h∙ha−1∙MJ−1∙mm−1∙yr−1. The Slope Length and Steepness factor (LS-factor) in the basin ranged between 0% and 13.47%. The Crop Management Factor (C-factor) values were obtained from a rescaling of the NDVI values derived for the study area and ranged from 0.26 to 0.55. Support practice (P-factors) were computed from the prevalent tillage practice in the basin and ranged from 0.27 to 0.40. The soil loss amount for the Kubanni basin was found to be 28441.482 tons∙ha−1∙yr−1, while the annual soil loss for the entire Kubanni drainage basin was found to be 49780.257 tons∙yr−1. The study has demonstrated the viability of coupling RUSLE model and Remote Sensing and Geographic Information System (GIS) techniques for the estimation of soil loss in the Kubanni drainage basin.
文摘Missense mutations in the leucine rich repeat kinase 2 (LRRK2) gene are the leading genetic cause of autosomal dominant familial Parkinson’s disease. We previously reported that two mutations within the ROC domain, namely R1441C and A1442P, exhibit increased protein degradation leading to lowered steady state LRRK2 protein levels in HEK293 cells. More recently, the common WD40 domain LRRK2 haplotype, Met2397, which is a risk factor for Crohn’s disease, has been shown to lower steady state protein levels in HEK293 cells. In view of recent evidence implicating LRRK2 and inflamemation in PD, we investigated the effects of Met2397 on LRRK2 expression, and compared them to the Thr2397 variant and other LRRK2 mutants. In this study, we transfected HEK293 cells with plasmid constructs encoding the different LRRK2 variants, and analyzed the resulting protein levels by Western blot and flow cytometry. Here we found that both the Met2397 and Thr2397 haplotypes yield similar levels of LRRK2 protein expression and do not appear to impact cell viability in HEK293 cells, compared to other LRRK mutants. Thus, we have concluded that the Met2397 haplotype is unlikely to play a role in LRRK2 mediated or idiopathic PD.
文摘An effective rapid assessment technique, called ＂P25 Scoring Method＂, has been developed and tested on 26 different case studies recently, in order to predict the collapse vulnerability of the R/C buildings. After a short description of the approach, the study presents the sensitivity study of the method to the selected structural parameters by considering incremental deviation of the final scores from the base model. Further, the methodology was applied to an additional 100 damaged buildings in order to check the reliability of the method and some necessary modifications have been applied to the algorithm after considering this larger database. The evaluation of the results has been interpreted as a beneficial guidance for local authorities. The risk bands are defined according to the final scores and the effect of changing the band-width has also been studied through a safe but an economical procedure. A satisfactory correlation of the method with real damage states is obtained and a ready-to-use methodology has been introduced for future studies.
