Metal magnetic memory testing for early damage assessment in ferromagnetic materials

In order to investigate the physical mechanism of metal magnetic memory testing, both the influences of earth magnetic field and applied stress on magnetic domain structure were discussed. Static tension and fatigue tests for low carbon steel plate specimens were carried out on hydraulic servo testing machine of MTS810 type and magnetic signals were measured during the processes by the type of EMS-2003 instrument. The results indicate that the initial magnetic signals of specimens are different before loading. The magnetic signals curves are transformed from initial random to regular pattern due to the effect of two types of loads. However, the shape and distribution of magnetic signal curves in the elastic region are different from that of plastic region in tension test. While in fatigue test those magnetic signals curves corresponding to different cycles are similar. The H_p(y) value of magnetic signals on the fracture zone increases dramatically at the breaking transient time and positive-negative magnetic poles occur on the two parts of fracture zone.

Real-time prediction of earthquake potential damage:A case study for the January 8,2022 M_(S) 6.9 Menyuan earthquake in Qinghai,China

It is critical to determine whether a site has potential damage in real-time after an earthquake occurs,which is a challenge in earthquake disaster reduction.Here,we propose a real-time Earthquake Potential Damage predictor(EPDor)based on predicting peak ground velocities(PGVs)of sites.The EPDor is composed of three parts:(1)predicting the magnitude of an earthquake and PGVs of triggered stations based on the machine learning prediction models;(2)predicting the PGVs at distant sites based on the empirical ground motion prediction equation;(3)generating the PGV map through predicting the PGV of each grid point based on an interpolation process of weighted average based on the predicted values in(1)and(2).We apply the EPDor to the 2022 M_(S) 6.9 Menyuan earthquake in Qinghai Province,China to predict its potential damage.Within the initial few seconds after the first station is triggered,the EPDor can determine directly whether there is potential damage for some sites to a certain degree.Hence,we infer that the EPDor has potential application for future earthquakes.Meanwhile,it also has potential in Chinese earthquake early warning system.

Response features of nonlinear circumferential guided wave on early damage in inner layer of a composite circular tube

A theoretical model to analyze the nonlinear circumferential guided wave(CGW) propagation in a composite circular tube(CCT) is established. The response features of nonlinear CGWs to early damage [denoted by variations in third-order elastic constants(TOECs)] in an inner layer of CCT are investigated. On the basis of the modal expansion approach, the second-harmonic field of primary CGW propagation can be assumed to be a linear sum of a series of double-frequency CGW(DFCGW) modes. The quantitative relationship of DFCGW mode versus the relative changes in the inner layer TOECs is then investigated. It is found that the changes in the inner layer TOECs of CCT will obviously affect the driving source of DFCGW mode and its modal expansion coefficient, which is intrinsically able to influence the efficiency of cumulative second-harmonic generation(SHG) by primary CGW propagation. Theoretical analyses and numerical simulations demonstrate that the second harmonic of primary CGW is monotonic and very sensitive to the changes in the inner layer TOECs of CCT, while the linear properties of primary CGW propagation almost remain unchanged. Our results provide a potential application for accurately characterizing the level of early damage in the inner layer of CCT through the efficiency of cumulative SHG by primary CGW propagation.

Assessment of the renal function, peroxidation damage and inflammatory injury after epalrestat combined with alprostadil treatment of early diabetic nephropathy

Objective:To study the renal function, peroxidation damage and inflammatory injury after epalrestat combined with alprostadil treatment of early diabetic nephropathy.Methods:90 patients with early diabetic nephropathy treated in our hospital between June 2011 and November 2015 were collected and divided into observation group and control group (n=45) according to the single-blind randomized control method. Observation group received epalrestat combined with alprostadil treatment, control group received alprostadil treatment alone, and the treatment of both groups lasted for 3 months. Before treatment and after 3 months of treatment, turbidimetric immunoassay was used to detect the renal function indexes in peripheral blood, rate method was used to detect the renal function indexes in urine, and ELISA method was used to detect the levels of peroxidation indexes and inflammation indexes.Results:Before treatment, differences in renal function, peroxidation damage and inflammatory damage indexes were not statistically significant between two groups of patients (P>0.05). After 3 months of treatment, creatinine (Scr), cystatin C (CysC),β2 microglobulin (β2-MG), N-acetyl-β-D-glucosaminidase (NAG), reactive oxygen species (ROS), advanced protein oxidation products (AOPPs), interleukin-8 (IL-8), interleukin-27 (IL-27) and procalcitonin (PCT) levels of observation group were lower than those of control group while catalase (CAT), total superoxide dismutase (TSOD), interleukin-4 (IL-4), interleukin-10 (IL-10) and interleukin-13 (IL-13) levels were higher than those of control group (P<0.05). Conclusions:Epalrestat combined with alprostadil can protect the renal function and inhibit the peroxidation damage and inflammatory injury in patients with early diabetic nephropathy.

Damage control orthopaedics: State of the art

Damage control orthopaedics(DCO) originally consisted of the provisional immobilisation of long bone-mainly femur-fractures in order to achieve the advantages of early treatment and to minimise the risk of complications, such as major pain, fat embolism, clotting, pathological inflammatory response, severe haemorrhage triggering the lethal triad, and the traumatic effects of major surgery on a patient who is already traumatised(the "second hit" effect). In recent years, new locations have been added to the DCO concept, such as injuries to the pelvis, spine and upper limbs. Nonetheless, this concept has not yet been validated in well-designed prospective studies, and much controversy remains.Indeed, some researchers believe the indiscriminate application of DCO might be harmful and produce substantial and unnecessary expense. In this respect, too,normalised parameters associated with the acid-base system have been proposed,under a concept termed early appropriate care, in the view that this would enable patients to receive major surgical procedures in an approach offering the advantages of early total care together with the apparent safety of DCO. This paper discusses the diagnosis and treatment of severely traumatised patients managed in accordance with DCO and highlights the possible drawbacks of this treatment principle.

Rapid repair techniques for severely earthquake-damaged circular bridge piers with flexural failure mode

In this study, three rapid repair techniques are proposed to retrofit circular bridge piers that are severely damaged by the flexural failure mode in major earthquakes. The quasi-static tests on three 1：2.5 scaled circular pier specimens are conducted to evaluate the efficiency of the proposed repair techniques. For the purpose of rapid repair, the repair procedure for all the specimens is conducted within four days, and the behavior of the repaired specimens is evaluated and compared with the original ones. A finite element model is developed to predict the cyclic behavior of the repaired specimens and the numerical results are compared with the test data. It is found that all the repaired specimens exhibit similar or larger lateral strength and deformation capacity than the original ones. The initial lateral stiffness of all the repaired specimens is lower than that of the original ones, while they show a higher lateral stiffness at the later stage of the test. No noticeable difference is observed for the energy dissipation capacity between the original and repaired pier specimens. It is suggested that the repair technique using the early-strength concrete jacket confined by carbon fiber reinforced polymer （CFRP） sheets can be an optimal method for the rapid repair of severely earthquake-damaged circular bridge piers with flexural failure mode.

药品专利信息登记反垄断问题研究

在药品专利纠纷早期解决机制中,药品上市许可持有人有义务保证所登记药品专利信息的完整性和准确性。药品上市许可持有人在具有市场优势地位情况下实施滥用药品专利信息登记权利的行为,有可能构成反垄断违法行为,需要进行反垄断规制。反垄断执法专门机构可以规范药品专利信息登记行为,仿制药企业可以提起反垄断民事诉讼,由此排除或者修正错误登记的药品专利信息。药品专利权人主观故意可以作为滥用垄断地位行为的构成要件,应当防止不适当地扩大药品专利信息登记的专利权范围。药品上市许可持有人应当在修改或者删除错误登记的药品专利信息以及对仿制药企业进行损害赔偿等方面承担法律责任。

多周期动态循环应力下的J-A-N力磁耦合机理模型

目前的力磁耦合J-A模型未考虑钉扎场的畴壁厚度与多周期动态循环应力的影响,导致J-A模型的应力磁化数值偏大,不能准确描述早期疲劳损伤。为此,基于畴壁理论和Burgers位错理论,引入畴壁厚度因子,改进J-A模型的钉扎场方程,进一步考虑循环载荷的应力幅、循环周次N等因素,建立了多周期动态循环应力下的J-A-N力磁耦合机理模型。获得了不同动态循环的应力幅值σa与平均应力σm下的磁化规律:相同循环周次下,σa主要影响应力磁化率,σm主要影响应力饱和磁化大小;σm相同时,随着σa的增大,达到应力饱和状态的速度升高;σa相同时,随着σm的增大,应力饱和磁化强度逐渐减小。为验证J-A-N模型有效性,对45钢三点弯曲试件进行了多周期动态循环应力下的磁场信号检测实验,实验结果与模型结果一致。

心电向量图诊断高血压早期心脏靶器官损害的临床应用及影响因素

目的探讨心电向量图(vectorcardiogram,VCG)对高血压心脏电活动异常的诊断价值,并分析早期心脏靶器官损害的影响因素。方法选取昆明市中医医院心血管病科2022年1月至2023年2月的高血压病住院患者80例,经超声心动图(ultrasound cardiogram,UCG)排外心脏结构异常。比较心电图(electrocardiogram,ECG)与VCG对异常心室除极与复极指标的检出情况。按心电向量检查结果将80例病例分为正常组(n=40)与异常组(n=40),比较2组早期心脏损害的相关影响因素指标,将差异有统计学意义的因素做二元Logistic回归分析,筛选出早期心脏损害的独立影响因素。结果VCG检出异常心室复极指标较ECG有优势(P<0.05),二者对异常除极指标的检出差异无统计学意义(P>0.05)。正常组与异常组比较,在年龄、规律服药、家族史、糖尿病、24 h平均收缩压(24 h average systolic blood pressure,24 h SBP)、白昼平均收缩压(daytime average systolic blood pressure,DSBP)、夜间平均收缩压(night average systolic blood pressure,NSBP)、血压负荷值、清晨血压、脉压差等指标上,差异有统计学意义(P<0.05)。二元Logistic回归分析显示,年龄[OR(95%CI)=0.891,0.998]、夜间平均收缩压[OR(95%CI)=1.018,2.10]、家族史[OR(95%CI)=0.029,0.499]、糖尿病[OR(95%CI)=0.042,0.916]是高血压早期心脏损害的独立影响因素。结论VCG为高血压早期心脏靶器官损害的有效检测手段。

基于稻田与台站气温的江西早稻高温热害指标对比

利用江西省90个县(区)2012-2021年国家气象站和2017-2021年8个稻田小气候站数据资料,分析稻田与相应台站气温差异,并对比台站日最高气温≥35℃指标H1(NS)、稻田日最高气温≥35℃指标H1(RS)、台站日最高气温≥37℃指标H2(NS)、稻田日最高气温≥37℃指标H2(RS)的高温热害统计结果,提出适用于江西的早稻高温热害指标,提升高温监测预警和防御能力。结果表明:(1)稻田较台站有降温效应,日最高气温(T_(max))、日平均气温(T)和日最低气温(T_(min))总体偏低0.6℃、0.4℃和0.3℃,且降温幅度随早稻生长增大,抽穗-成熟期>移栽-孕穗期>播种-移栽期。(2)高温期间,晴天条件下稻田降温幅度最大,T、T_(max)和T_(min)较相应台站平均偏低0.8℃、1.0℃和0.7℃,阴天多云和雨天稻田降温幅度总体较为接近。(3)H1(NS)热害下,稻田与相应台站的逐日气温、逐小时气温均差异显著,且夜间稻田降温强度大于白天。稻田气温总体偏低1.2℃左右,金溪稻田偏低最多,T、T_(max)和T_(min)平均偏低1.5℃、1.1℃和2.6℃。(4)不同指标统计近10a高温热害县(区)数、平均持续时间、灾害县(区)平均减产率模拟值和全省减产率模拟值,均以H1(NS)最大、H2(RS)最小。H2(NS)与H1(RS)统计的平均持续时间、灾害县(区)平均减产率模拟值和全省减产率模拟值差异不显著,但均与H1(NS)、H2(RS)统计结果差异显著,且H2(NS)统计的全省减产率模拟值与实际更接近。台站T_(max)≥37℃更适合作为江西省早稻高温热害指标。

婺源主要气象灾害对茶树生育进程的影响研究

为明确婺源茶树主要农业气象灾害的变化特征,掌握气象灾害对茶树生长发育的影响规律,提高茶园防灾减灾能力,利用Pearson相关性分析等对茶树生育进程与气象灾害的关系进行分析,并提出灾害应对措施。结果显示,2010—2022年婺源茶叶早春霜冻累计出现日数呈减少的趋势,夏季热害和冬季冻害具有偶发性。在3种主要气象灾害中,早春霜冻对茶树生育期的影响最大,早春霜冻日数越多,茶树生育进程越推迟;夏季热害对茶树生育进程有一定影响;冬季冻害对茶树生育进程影响不显著。根据灾害发生规律,提出了相关应对措施。

基于超声扩散场的焊接节点疲劳损伤早期检测及剩余寿命评估

钢结构焊接节点在疲劳载荷作用下易发生损伤、破坏,目前基于超声技术检测疲劳损伤的方法已得到初步验证,但早期裂纹萌生预警和剩余寿命评估仍存在困难和挑战。该研究基于超声扩散场能量密度提出一种检测焊接节点疲劳损伤的方法。该方法通过计算有损和无损状态下超声能量密度的差异,定义焊接节点疲劳损伤指数;采用对接焊缝和十字形传力角焊缝试件,验证损伤指数对焊接节点疲劳损伤的敏感性和普适性;而后,对早期裂纹萌生预警和剩余寿命评估与棘轮应变检测结果进行对比。试验结果表明:所提出的损伤指数变化趋势与棘轮应变检测结果吻合度高;焊接节点疲劳裂纹扩展时,损伤指数增长尤为快速;当裂纹萌生时,损伤指数表现出突然增大的趋势,据此定义早期裂纹萌生预警判据,实现对焊接节点疲劳全寿命60%~80%的早期剩余寿命评估;同时,根据损伤指数曲线明显的谷值点,实现焊接节点寿命30%~50%的早期剩余寿命评估。

多模式预报产品对长江中下游地区早稻高温热害识别能力的比较

利用CLDAS实况融合产品,比较分析欧洲中心高分辨率模式(ECMWF_HR)、GRAPES全球模式(GRAPES_GFS)以及中央气象台指导预报(SCMOC)3种模式预报产品对2021-2023年长江中下游地区早稻孕穗-成熟期提前1~3d、1~5d、1~7d条件下高温热害发生与强度的识别能力。结果表明:(1)针对高温热害的发生预报,SCMOC产品识别效果最优,各预报时段命中率(Probability of detection,POD)均大于0.6,TS(Threat score)评分在0.49~0.59;GRAPES_GFS产品的POD同样大于0.6,但误报率(False alarm ratio,FAR)大于0.3,TS评分为0.45~0.52;ECWMF_HR产品的识别效果最差,POD小于0.4,TS评分小于0.3。(2)对于高温热害强度识别,SCMOC产品与CLDAS产品的危害热积温数值最为接近,相关系数(Cor)大于0.6,均方根误差(RMSE)随预报时段增加分别为1.57℃·d、2.57℃·d、3.43℃·d;GRAPES_GFS产品对湖北大部和江西北部的预报偏强,对湖南南部预报明显偏弱,且与CLDAS产品的Cor较SCMOC产品偏低约0.06,RMSE偏高约0.4℃·d;ECMWF_HR产品与CLDAS产品的Cor在各预报时段均小于0.4,RMSE较SCMOC产品偏高0.5~1.0℃·d。(3)针对不同年份的高温热害,SCMOC与GRAPES_GFS产品对研究区域早稻高温热害影响较重的2022年和2023年识别效果较好,但前者对高温热害影响较弱的2021年识别效果更优;ECMWF_HR产品对2021-2023年研究区域高温热害的发生与强度均呈显著偏弱预报。综上所述,SCMOC预报产品对长江中下游早稻高温热害的识别效果较优,能为早稻高温热害防灾减灾工作提供参考。

胶结充填体早期损伤对后期力学性能的影响

目的为了探明胶结充填体早期损伤对后期承载性能的影响,方法通过开展早期受损充填体经养护一定龄期后的单轴压缩试验,以损伤龄期和压损程度为变量,以受损充填体的后期变形特性、抗压强度、弹性模量为后期力学性能评价指标,分析充填体损伤龄期和压损程度对其后期力学性能的影响规律。结果结果表明:在同一损伤龄期下,充填体在80%压损下后期峰值应力及残余应力最低;压损程度对龄期3,7 d的充填体后期变形特性影响较小,对龄期14,21 d的充填体后期变形特性弱化作用较大;80%以下的压损程度对龄期3,7 d充填体后期抗压强度影响较小,各个压损程度对龄期14,21 d充填体后期抗压强度影响较大,压损程度越大,后期抗压强度越低;各龄期充填体后期弹性模量均随压损程度的增大而增大。养护龄期14 d之后的充填体受损后对其后期力学性能影响显著,且不同压损程度对龄期14 d之后的充填体后期力学影响显著。结论研究结果可为上向水平充填采矿方法中充填质量的控制提供理论指导。

基于“厥阴为阖”探讨早醒型失眠的证治

早醒型失眠是以入睡尚可、凌晨易醒为主要表现的睡眠障碍,其发病主要责之阳气非时早出于阴,抑或适时而阳气不生。厥阴为阖承载阴尽阳生之转换,内涵阴气潜藏与阳气生发之功用,是中医六经阴阳气化功能的体现。本文基于厥阴为阖理论,结合六经辨证及阴阳学说,深入剖析早醒型失眠的证治。认为厥阴阳郁寒胜属阖之太过,当解郁通阳,温肾散寒;厥阴阴虚热胜则属阖之不及,当清热安神,滋阴养血;厥阴寒热错杂证属阖之太过与不及并存,当清上温下,平调阴阳。

多次采掘扰动煤体力学特性演化规律试验研究

【目的】矿井开采过程中,多次采掘扰动所引发的循环加卸载效应对煤体力学性能的改变是导致冲击地压灾害发生的原因之一。揭示煤体在此过程中的关键力学参数响应特征及损伤机制可为冲击失稳状态判别提供依据,对提升灾害预测能力具有重要意义。【方法】采用大尺寸类煤体试样,将准静态单轴循环加卸载和冲击动载相结合,精确捕捉试验过程中试样应力、应变以及声发射等响应信息,全面揭示多次采掘扰动作用下试样力学参数变化规律及损伤演化过程。【结果和结论】结果表明:(1)最高加载载荷是影响多次循环加卸载作用下损伤煤体力学性能的最关键因素,随着循环次数的增加,对于加载至屈服阶段的试样,其残余应变呈现先增大后减小再增大的变化趋势,耗散能密度及加载至最高载荷时所对应的声发射特征值逐渐增大,试样损伤程度不断增加;对于加载至弹性阶段的试样,其上述力学特征参数均呈现先减小后增大的变化趋势;而对于试验过程始终处于压密阶段的试样,3组数据均呈现不断减小的变化趋势。(2)在施加冲击动载作用后,3组试样均发生冲击破坏,前期准静态循环加卸载试验中所受载荷越小的试样,其损伤程度越小,发生冲击破坏所需的诱发动载强度越大,峰值破坏弹性模量越大。(3)从应变与能量2个角度对试样损伤度进行表征,通过对比分析,发现能量损伤度对此试验过程中试样损伤程度判别更为敏感。(4)对试样孔洞内部冲击破裂特征观察发现,试样在发生冲击破坏过程中共经历平静期、颗粒弹射期、稳定破坏期以及冲击破坏期4个阶段。(5)可将循环加卸载后期残余应变增大起始值以及冲击破坏过程中稳定破坏前期阶段作为损伤煤体冲击失稳前兆预警信息。研究获得了受多次采掘扰动煤体力学特性的演化规律,可为工程中损伤煤体冲击失稳状态判别提供理论依据,对于及时发现损伤煤体的潜在失稳风险,从而优化支护方案,确保矿井安全开采具有重要意义。

肝豆灵汤治疗肝豆状核变性早期肾损害临床观察

目的:观察肝豆灵汤治疗痰瘀互结型肝豆状核变性患者早期肾损害的临床疗效。方法:选取安徽中医药大学第一附属医院符合肝豆状核变性早期肾损害诊断的住院患者70例,随机分为两组各35例。两组均予二巯基丙磺酸钠常规治疗,对照组另予百令胶囊,治疗组予肝豆灵汤口服,6天为1个疗程,共治疗4个疗程。观察两组患者临床疗效,比较治疗前后两组患者24小时尿铜、肾功能指标[肌酐(CREA)、尿素氮(BUN)、胱抑素C(CysC)]、尿系列蛋白指标[尿视黄醇结合蛋白(URBP)、尿β_(2)微球蛋白(Uβ_(2)-MG)、尿转铁蛋白(UTRF)、尿免疫球蛋白G(UIgG)、尿微量白蛋白(mALB)、尿α_(1)微球蛋白(Uα_(1)-MG)、尿N-乙酰-β-D-氨基葡萄糖苷酶(UNAG)]、24 h尿总蛋白定量(24 hUPQ)、氧化应激指标[超氧化物歧化酶(SOD)、丙二醛(MDA)、谷胱甘肽过氧化物酶(GSH-PX)、过氧化氢酶(CAT)]及不良反应发生情况等。结果:治疗后,治疗组总有效率为91.43%,优于对照组的68.57%(P﹤0.05);两组24小时尿铜在治疗后均升高(P﹤0.05),治疗组升高幅度优于对照组(P﹤0.05);治疗组CREA、CysC、BUN水平降低,降低幅度优于对照组(P﹤0.05);治疗组URBP、Uβ_(2)-MG、UTRF、UIgG、mALB、Uα_(1)-MG、UNAG、24 hUPQ、UTP值均有所下降,且治疗组下降幅度优于对照组(P﹤0.05);两组患者的SOD、GSH-PX、CAT水平均明显上升,MDA水平明显下降(P﹤0.05),且治疗组改善程度优于对照组(P﹤0.05)。结论:肝豆灵汤能有效改善痰瘀互结型肝豆状核变性早期肾损害患者的症状,促进体内排铜,保护肾功能,改善早期肾损害,临床疗效较好。

尿微量白蛋白、N-乙酰-β-D-葡萄糖苷酶及血清胱抑素C联合检测在糖尿病早期肾损伤诊断中的价值分析

目的分析尿微量白蛋白(microalbuminuria,m-ALB)、N-乙酰-β-D-葡萄糖苷酶(N-acetyl-β-D-glucosidase,NAG)及血清胱抑素C(cystatin C,CysC)联合检测在糖尿病早期肾损伤(early kidney damage in dia⁃betes,EKDID)诊断中的价值。方法回顾性选取2021年6月—2022年12月日照市人民医院收治的60例EKDID患者(A组)、60例单纯糖尿病患者(B组)和30名健康体检人群(C组)的临床资料,均进行尿m-ALB、NAG及血清CysC检查,比较3组尿m-ALB、NAG及血清CysC水平,并分析各项指标单独及联合检测的灵敏度、特异度、准确度、阳性预测值、阴性预测值。结果A组尿m-ALB、NAG及血清CysC水平均高于B组、C组,差异有统计学意义(P均<0.05);B组、C组间各指标水平比较,差异无统计学意义(P均>0.05)。三项指标联合检测EKDID的灵敏度、阴性预测值均高于各单项及两两组合检测,差异有统计学意义(P均<0.05)。结论尿m-ALB、NAG及血清Cys三项指标联合检测可明显提高诊断EKDID的价值。

滋生青阳汤防治高血压早期肾损害的疗效及对血压昼夜节律影响

目的:观察孟河医派滋生青阳汤防治高血压早期肾损害的疗效及对血压昼夜节律影响。方法:将符合标准的80例确诊为高血压早期肾损害的患者随机分为观察组和对照组,每组各 40 例。对照组给予奥美沙坦氨氯地平常规治疗,观察组在对照组的基础上加用滋生青阳汤治疗。比较2组的临床疗效、中医症候疗效及胱抑素 C(Cys-C)、尿微量白蛋白(mALB)、尿β-微球蛋白水平。结果:观察组中医症候总有效率高于对照组,差异有统计学意义(P<0.05)。2组治疗前 Cys-C、尿β-微球蛋白及尿 mAlb 水平无明显差异(P>0.05);治疗8周后,观察组的 Cys-C 、尿β-微球蛋白及尿mAlb水平均低于对照组,差异有统计学意义(P<0.05)。2组组内比较,治疗 8周后对照组和观察组的Cys-C、尿β-微球蛋白及尿 mAlb 水平均低于治疗前,差异有统计学意义(P<0.05)。2组患者治疗前血压水平无差别,治疗后,观察组 24 h平均收缩压和 24 h平均舒张压水平低于对照组;2组患者治疗前血压昼夜节律无差别,治疗后,观察组杓型血压患者高于对照组,差异有统计学意义(P<0.05)。结论:滋生青阳汤联合西药常规治疗对早期高血压肾损害具有较好治疗效果,能够明显改善患者中医症状和肾功能,还可以调节血压昼夜节律,值得临床推荐。

广西双季早稻高温热害精细化风险评估与区划研究

基于灾害风险分析原理,利用广西89个国家级气象站1970─2020年气象观测数据和广西各主产市(县)早稻种植面积、产量资料,以及相关地理信息数据等,从灾害致灾因子危险性、承灾体暴露度、承灾体脆弱性以及防灾减灾能力等方面筛选风险评估指标,采用灾害风险指数法、层次分析法等技术方法构建了广西双季早稻高温热害的风险评估模型,并利用GIS技术对广西早稻高温热害进行了风险评估分析和精细化风险区划。结果表明:广西早稻高温热害的综合风险高值区主要位于左江河谷、右江河谷区域和桂中盆地等;低风险区主要分布在桂西北和桂北山区。本研究结果可为广西早稻生产趋利避害、优化布局、防灾减灾提供决策参考。