A mini review and hypothesis for coronavirus detection using photonics: surface enhanced Raman scattering and fluorescence resonance energy transfer

COVID-19 has devastated numerous nations around the world and has overburdened numerous healthcare systems,which has also caused the loss of livelihoods due to prolonged shutdowns and further led to a cascading effect on the global economy.COVID-19 infections have an incubation period of 2–7 days,but 40 to 45%of cases are asymptomatic or show mild to moderate respiratory symptoms after the period due to subclinical lung abnormalities,making it more likely to spread the pandemic disease.To restrict the spread of the virus,on-site diagnosis methods that are quicker,more precise,and easily accessible are required.Rapid Antigen Detection Tests and Polymerase Chain Reaction tests are currently the primary methods used to determine the presence of COVID-19 viruses.These tests are typically time-consuming,not accurate,and,more importantly,not available to everyone.Hence,in this review and hypothesis,we proposed equipment that employs the properties of photonics to improve the detection of COVID-19 viruses by taking the advantage of typical binding of coronavirus with angiotensin-converting enzyme 2(ACE2)receptors.This hypothetical model would combine Surface-Enhanced Raman Scattering(SERS)and Fluorescence Resonance Energy Transfer(FRET)to provide great flexibility,high sensitivities,and enhanced accessibility.

Evolution of Electron Phase Orbits Based on Multi-photon Nonlinear Compton Scattering

The electron movement based on the multi-photon nonlinear Compton scattering with the extra-intense stationary laser field is discussed by using KMR (Kroll-Morton-Rosenbluth) theory.We find that there exists only an evolution from periodicity to non-periodicity of the un-captured electron phase orbits after the energy exchange between the electron beam and laser fields.With the increase of the absorbed photon number n by an electron, this evolution will be more and more faster, while it is rapidly decreased with the enhancement of the collision non-flexibility ξ of the electrons and photons; When the electrons are captured by the laser fields, the evolution is finished, the electrons will stably transport,and the photons dont give up the energy to these electrons.

Single Photon Scattering in a Pair of Waveguides Coupled by a Whispering-Gallery Resonator Interacting with a Semiconductor Quantum Dot

The single photon scattering properties in a pair of waveguides coupled by a whispering-gallery resonator in- teracting with a semiconductor quantum dot are investigated theoretically. The two waveguides support four possible ports for an incident single photon. The quantum dot is considered a V-type system. The incident direction-dependent single photon scattering properties are studied and equal-output probability from the four ports for a single photon incident is discussed. The influences of backscattering between the two modes of the whispering-gallery resonator for incident direction-dependent single photon scattering properties are also pre- sented.

Energy distributions of multiple backscattered photons in materials

Backscattering of gamma photons from a material is of fundamental importance in radiation shielding,industrial and medical applications, radiation dosimetry,and non-destructive testing. In Compton scattering, incident photons undergo multiple scatterings within the material(target) before exiting. Gamma photons continue to soften in energy as the number of scatterings increases in a thick target; in other words, the energy of gamma photons decreases as the scatterings increase in case of a thick target and results in the generation of singly and multiply scattered events. In this work, the energy distribution of backscattered gamma photons with backscattering intensity and energy probabilities were calculated by using the Monte Carlo method for metallic, biological, and shielding materials with various thicknesses of slab geometry. The materials under study were targeted with gamma photons of 0.279, 0.662, 1.250, and 2.100 Me V energies. In addition, the energy distributions of multiply scattered gamma photons were studied for materials with infinite geometry.The results are presented and discussed in detail by comparing with other Monte Carlo calculations.

Scattering of a single photon in a one-dimensional coupled resonator waveguide with a Λ-type emitter assisted by an additional cavity

We analyze the transport property of a single photon in a one-dimensional coupled resonator waveguide coupled with a Λ-type emitter assisted by an additional cavity. The reflection and transmission coefficients of the inserted photon are obtained by the stationary theory. It is shown that the polarization state of the inserted photon can be converted with high efficiency. This study may inspire single-photon devices for scalable quantum memory.

Polarization Conversion of Single Photon via Scattering by a Λ System in a Semi-Infinite Waveguide

We theoretically investigate single-photon polarization conversion via scattering by an atom with Λ configuration coupled to a semi-infinite waveguide and discuss the two cases in which the Λ system is non-degenerated and degenerated. By applying the hard-wall boundary condition of the semi-infinite waveguide, it is found that singlephoton polarization conversion can be realized with unit probability for both cases under the ideal condition.Together with the polarization conversion, the frequency conversion of a single photon can also be realized with unit probability in the ideal case if the Λ system is not degenerated.

Single-Photon Scattering by a Three-level System Interacting with a Whispering-Gallery Resonator Coupled to One-Dimensional Waveguide：

We investigate theoretically the single-photon scattering by a A-type three-level system interacting with a whispering-gallery-type resonator which is coupled to a one-dimensional waveguide by full quantum-mechanical approach. The single-photon transmission amplitude and reflection amplitude are obtained exactly via real-space approach. The single-photon transport properties controlling by classic optical field are discussed. The critical coupling condition in the coupled waveguide-whispering-gallery resonator-atom with three-level system is also analyzed.

Photon Acceleration of Laser-plasma Based on Compton Scattering

The one-dimensional electron density disturbance is studied by using the inelastic collision model of the relativity electron and photon group, the relativity theory, the momentum equation and the continuity equation, which is generated by a driving laser pulse and scattered laser pulse propagating through a tenuous plasma, and the electron density disturbance is closely associated with the incident laser and scattering laser. The electron plasma wave(EPW)is formed by the propagation of the electron density disturbance. Owing to the action of EPW, the increasing of the frequency of the photons in the incident laser pulses that there is a distance with the driving laser pulses is studied by using optical metric. The results show that it is possible that the photon will gain higher energy from the EPW when photon number is decreased and one-photon Compton scattering enters, the photon will be accelerated.

Influences of Uncaptured Electron on Energy Conversion of Photon Compton Scattering in High Power Laser-plasma

Using the single particle theory and the non-flexibility collision model of electron and photon, the influence of the uncaptured electrons on the energy conversion efficiency of multi-photon nonlinear Compton scattering in the extra stationary laser-plasma is investigated. It shows that in extra stationary laser-plasma,the uncaptured electrons make the Δω of the scattering frequency of the multi-photon Compton fall down with the increases of the incident radiation electron speed,the materials of the incident collision of electron and photon, and the number of the photons which work with the electrons at the same time. Under the modulation of the uncaptured electrons to the laser field, the energy conversion efficiency between electrons and photons will fall down with the increase of the electron incident radiation speed, using the low-power electrons for incident source, the loss can be efficiently reduced.

Photon Polarizationin Photonic Crystal Fibers under Compton Scattering

Using the quantum invariant theory and unitary transformation means, we study the influences of multi-photon nonlinear Compton scattering on the photon polarization in photonic crystal fibers(PCF). The results show that the photon polarization of the incident photon changes a lot due to scattered optical, and its general geometric phase factor, Hamiton number and evolution operator are definited both by the incident and scattered optical.

Single-photon scattering by two separated atoms in a supercavity

We study the single-photon scattering along a one-dimensional cavity array with two distant two-level atoms in a supercavity,which aims to simulate a recent x-ray experiment [Nature 482,199（2012）].Without introducing dissipation,we find that when one atom is exactly located at a node of a mode of the supercavity and the other is at the antinode of that mode,no splitting of the reflectivity peak can appear.Nevertheless,the atom at the node significantly changes the positions of the reflectivity valleys.On the other hand,when the atom is shifted a little from the exact node,then the splitting can appear.We also explain these results with an analysis based on the general formal scattering theory.Our result implies the importance of non-resonant modes of the supercavity in our problem.

On Unparticle Searches through Photon-Photon Scattering

In this work, we study the effects of the spin-0 unparticle on γγ → γγ process. From the numerical results, we show that the cross section with unparticle effect should be about 1027 - 1030 times larger than the one that is confirmed by QED calculation. This could have important implications for unparticle searches and for the measurement of the photon-photon cross section.

Simultaneous measurements of global vibrational spectra and dephasing times of molecular vibrational modes by broadband time-resolved coherent anti-Stokes Raman scattering spectrography

In broadband coherent anti-Stokes Raman scattering （CARS） spectroscopy with supercontinuum （SC）, the simultaneously detectable spectral coverage is limited by the spectral continuity and the simultaneity of various spectral components of SC in an enough bandwidth. By numerical simulations, the optimal experimental conditions for improving the SC are obtained. The broadband time-resolved CARS spectrography based on the SC with required temporal and spectral distributions is realised. The global molecular vibrational spectrum with well suppressed nonresonant background noise can be obtained in a single measurement. At the same time, the measurements of dephasing times of various molecular vibrational modes can be conveniently achieved from intensities of a sequence of time-resolved CARS signals. It will be more helpful to provide a complete picture of molecular vibrations, and to exhibit a potential to understand not only both the solvent dynamics and the solute-solvent interactions, but also the mechanisms of chemical reactions in the fields of biology, chemistry and material science.

Influence of Characteristics of Substance on Parameters of Interaction of Photons High Energy with Free Electrons

Various variants of interaction of photons high energy with free electrons in substance are investigated. It is shown, that among these variants, in substance can be observed: absorption of a photon by electron, coherent and not coherent scattering of photons, a stop electron after interaction with a photon. Dependence of change of length of a wave of a photon after interaction with electron from parameters of substance and speed of movement electron is found.

Analysis of Dose Calculation Accuracy in Cone Beam Computed Tomography with Various Amount of Scattered Photon Contamination

Cone-beam computed tomography (CBCT) images have inaccurate CT numbers because of scattered photons. Thus, quantitative analysis of scattered photons that affect an electron density (ED) curve and calculated doses may be effective information to achieve CBCT-based radiation treatment planning. We quantitatively evaluated the effect of scattered photons on the accuracy of dose calculations from a lung image. The Monte Carlo method was used to calculate CBCT projection data, and we made two calibration curves for conditions with or without scattered photons. Moreover, we applied cupping artifact correction and evaluated the effects on image uniformity and dose calculation accuracy. Dose deviations were compared with those of conventional CT in conventional and volumetric intensity modulated arc therapy (VMAT) planning by using γ analysis and dose volume histogram (DVH) analysis. We found that cupping artifacts contaminated the scattered photons, and the γ analysis showed that the dose distribution was most decreased for a scattered photon ratio of 40%. Cupping artifact correction significantly improved image uniformity;therefore, ED curves were near ideal, and the pass rate results were significantly higher than those associated with the scattered photon effect in 65.1% and 78.4% without correction, 99.5% and 97.7% with correction, in conventional and VMAT planning, respectively. In the DVH analysis, all organ dose indexes were reduced in the scattered photon images, but dose index error rates with cupping artifact correction were improved within approximately 10%. CBCT image quality was strongly affected by scattered photons, and the dose calculation accuracy based on the CBCT image was improved by removing cupping artifacts caused by the scattered photons.

First-order approximate analytical expressions of oblique incident elastic wave at an interface of porous media saturated with a nonviscous fluid

The analysis technology of Amplitude Variation with Offset(AVO)is one of the important methods for oil and gas reservoir prediction.Zoeppritz equation and its approximations are the theoretical basis of AVO analysis,which assumes that the upper and lower media of a horizontal interface are single-phase media.Limited by this assumption,AVO analysis has limited prediction and identification accuracy for complex porous reservoirs.In view of this,the first-order approximate analytical expressions of oblique elastic wave at an interface of porous media are derived.Firstly,the incident and scattering characteristics of various waves at the interface of porous media are analyzed,and the displacement vectors generated by these elastic waves are described by exponential function.Secondly,the kinematic and dynamic boundary conditions at the interface of porous media are discussed.Thirdly,by substituting the displacement vectors of incident and scattered waves into boundary conditions,the exact analytical equation is derived.Then,considering the symmetry of scattering matrix in the equation,the exact analytical expressions of each scattered wave are obtained.Furthermore,under the assumptions of small incident angle,weak elasticity at an interface of porous media,and ignoring the second-and higherorder terms,the first-order approximate analytical expressions are derived.Establishing a model of sandstone porous media with different porosity in upper and lower media,the correctness of the approximate analytical expressions is verified,and the elastic wave response characteristics of lithology and pore fluids are analyzed.

Second-order Nonlinearities of CdS Nanoparticles Studied by Hyper-Rayleigh Scattering Technique

A series of CdS nanoparticles with different surfaces were prepared by colloidal chemical method and reverse micelle method. Their second-order nonlinear optical (NLO) properties were experimentally studied in solution by newly developed hyper-Rayleigh scattering (HRS) technique. The results show that 'per particle' first-order hyperpolarizability beta values are sensitive To the synthetic method and the surface chemical modification.

The Coulomb Resonances, the Quasi-Real Photons and Electro-Disintegration of Nuclei by High-Energy Electrons

Various aspects of the influence of the quasi-real photons and the Coulomb resonances on the formation of the crosssection of inelastic scattering of high energy electrons on atomic nuclei are investigated. Emiss is the energy that disappears in the processes of knocking-on of protons in the reactions . A new hypothesis that interprets the origin of the energy losses is proposed. Specific experiments that can confirm or refute this hypothesis are proposed as well. The “regularized” cross-sections of electro-disintegration of nuclei by high-energy electrons are calculated in the framework of the nuclear shell model. It is shown that for the experimental verification of the existence of Coulomb resonances, it is necessary to investigate the processes at relatively small angles of scattering. The peculiarities of numerical methods that are crucial in the investigation of inelastic scattering of high-energy electrons on nuclei in the framework of the nuclear shell model are analyzed in this work as well. The cross-sections of the scattering of high-energy electrons on the angle are calculated. It is shown that the orthogonality of the wave functions of a knocked-on proton in the initial and final states plays an important role in the interpretation of this process.

On-chip stimulated Brillouin scattering[Invited]

On-chip stimulated Brillouin scattering(SBS)has attracted extensive attention by introducing acousto-optic coupling interactions in all-optical signal processing systems.A series of chip-level applications such as Brillouin lasers,amplifiers,gyroscopes,filters,and nonreciprocal devices are realized based on Brillouin acousto-optic interaction.Here,we first introduce the fundamental principle of SBS in integrated photonics and a method for calculating Brillouin gain;then we illustrate the Brillouin effect on different material platforms with diverse applications.Finally,we make a concise conclusion and offer prospects on the future developments of on-chip SBS.

基于分子干涉函数的光子-原子相干散射截面计算方法研究

X射线衍射在物质结构分析和材料无损检测领域有着广泛的应用,其基本物理原理为光子与物质发生的相干散射。传统的相干散射截面计算方法基于独立原子形状因子近似方法,忽略了光子动量转移较小时与原子发生相互作用时的分子干涉效应,影响相干散射截面的计算精度。因此,为了获得光子动量转移较小时精确的相干散射截面,本文在核数据处理程序NECP-Atlas中对基于分子干涉函数的光子-原子相干散射截面计算方法进行研究,利用分子动力学模拟方法计算分子干涉函数,对蒙特卡罗程序使用的ACE格式数据库中的原子形状因子进行修正,并给出了模拟得到的水分子和乙醇分子的分子干涉函数,对基于独立原子形状因子近似方法和考虑分子干涉效应计算得到的水和乙醇的散射成像结果进行了对比分析。数值结果显示:基于分子动力学模拟得到的分子干涉函数计算得到的水的散射成像结果与文献结果吻合较好;同时,当光子动量转移较小时,分子干涉效应对相干散射的次级光子角度分布有着显著影响。本文建立的光子-原子相干散射截面计算方法可显著提高光子动量转移较小时的相干散射次级光子角度分布计算精度,可为X射线衍射模拟提供数据基础。