Obstructive sleep apnea-hypopnea syndrome immunological relationship

Obstructive sleep apnea-hypopnea syndrome(OSAHS)is a complex disorder cha-racterized by symptoms resulting from intermittent hypoxia and hypopnea,with research indicating a crucial role of immune system dysregulation and genetic variations in its pathogenesis.A recent Zhao et al study utilizes Mendelian ran-domization analysis to explore the causal relationship between immune cell characteristics and OSAHS.The study identifies specific lymphocyte subsets as-sociated with OSAHS,providing valuable insights into the disease's pathophy-siology and potential targets for therapeutic intervention.The findings underscore the significance of genetic and immunological factors in sleep disorders,offering a fresh perspective on OSAHS's complexities.Compared to existing literature,Zhao et al's study stands out for its focus on genetic markers and specific immune responses associated with OSAHS,expanding upon previous research primarily centered on systemic inflammation.In conclusion,the study represents a signi-ficant advancement in the field,shedding light on the causal role of immune cells in OSAHS and paving the way for future research and targeted treatments.

Isolation and Biological Characteristics of Bacteriophage of an Antibiotic-resistant Escherchia coli Strain

In this study, bacteriophage of an antibiotic-resistant Escherchia coil strain isolated from feces of chicken was isolated. Its host range was determined by the method of spotting sample on monolayer agar, and its lysis titer, optimal multiplicity of infection （MOI）, temperature tolerance and pH tolerance were determined by the double-layer agar plate method. The results showed that the bacteriophage had a broad host range. The biological assay demonstrated that two strains of E. coil were fully lysed and one strain of E. coil was weakly lysed by the bacteriophage. The lysis titer and MOI of the bacteriophage were 1.20×10^8 PFU/ml and 1, respec- tively. Under the optimum temperature of 40℃, the Jysis titer of the bacteriophage reached 8.90×10^9 PFU/ml; however, the bacteriophage lost its infectivity at the tem- perature of 80℃. In the pH range of 5-11, the lysis titer of the bacteriophage ranged from10^6 to 10^9 PFU/mI. Under the condition of pH 4 and 12, the bacterio- phage was invalid.

Design of Offshore Wind Power Foundation with Multi-bucket

Three- and four-bucket offshore wind power foundations with a new form of force-transferring structure are proposed in this paper, and the integrated finite element model of foundation-soil-transition structure is established by using ABAQUS. The carrying capacity of the proposed foundations is studied under vertical load, horizontal load and bending moment. It can be seen that the vertical bearing capacity of multi-bucket foundation can be roughly estimated by the vertical bearing capacity of single-bucket; the horizontal bearing capacity of the three-bucket foundation scheme is controlled by displacement, while that of the four-bucket foundation scheme is controlled by the internal forces of soils. Moreover, the carrying capacity is provided by the overall structure formed by multi-bucket before soil failure. Compared with the conventional single-bucket foundation, there are mainly tension and pressure that are applied to the multi-bucket foundation, so that the carrying capacity of the foundation can be fully utilized. The probability of soil failure can be well reduced with the proposed multi-bucket foundation, and the stress transmission of force-transferring structure is more consistent through steel beams with variable cross-section.

Characterization of TGMS Line 33S in Rice

The research expIored morphoIogical characteristics, fertiIity, and tralts re-Iating to outcrossing of 33S which was of good shapes in pIant and Ieaf, with Iow infertiIity temperature, earIy fIowering period, high fIowering rate before noon, and good tralts reIating to outcrossing.

Developments of parabolic equation method in the period of 2000–2016

Parabolic equation （PE） method is an efficient tool for modelling underwater sound propagation, particularly for problems involving range dependence. Since the PE method was first introduced into the field of underwater acoustics, it has been about 40 years, during which contributions to extending its capability has been continuously made. The most recent review paper surveyed the contributions made before 1999. In the period of 2000-2016, the development of PE method basically focuses on seismo-acoustic problems, three-dimensional problems, and realistic applications. In this paper, a review covering the contribution from 2000 to 2016 is given, and what should be done in future work is also discussed.

Dynamic characteristics and application of dual throat fluidic thrust vectoring nozzle

Thrust vectoring technology plays an important role in improving the maneuverability of aircraft.In order to overcome the disadvantages of mechanical thrust vectoring nozzles,such as complications of structure and significant increases in weight and cost,fluidic thrust vectoring noz-zles are proposed.Dual Throat fluidic thrust vectoring Nozzle(DTN)has received wide attention due to its excellent thrust vectoring efficiency and minimal thrust loss.In this study,three-dimensional unsteady numerical simulations of a single axisymmetric DTN are conducted first to analyze its dynamic response.Then the pitch and yaw control characteristics of DTN equipped on a flying-wing aircraft are investigated.It is found that the dynamic response will experience three stages:rapid-deflecting stage,oscillating stage,and steady stage.A complete recirculation zone forms at the end of the rapid-deflecting stage,which pushes the primary flow to attach to the wall opposite the secondary injection.Meanwhile,the exhaust flow is deflected.In terms of DTN's appli-cation,the DTN equipped on the flying-wing aircraft is capable of providing effective pitch and yaw moments at all angles of attack and Mach numbers.In addition,continuous pitch and yaw moments can be obtained by adjusting the secondary mass flow ratios.The control moment is gen-erated due to the asymmetrical pressure distribution of nozzle surface,which is mainly contributed by the pressure decrease on the secondary injection surface.Moreover,the DTN equipped on the flying-wing aircraft has a relatively high thrust vectoring efficiency of around 5°/%and a thrust coefficient of around 0.95 when nozzle pressure ratio equals 4.These results provide an important theoretical basis for the practical application of DTN.

Multi–physical-field characteristics modeling and structure optimization for kW-level ultra-high-speed PM motors with integrated support system

In the aerospace industry,the low-mass ultra-high-speed flywheel system play a critical role.In this paper,a kW-level Ultra-High Speed Permanent Magnet Synchronous Motor(UHSPMSM)as the core component of flywheel system is proposed and analyzed with consideration of multiple physical fields,including electromagnetic characteristics,mechanical strength and rotor dynamics.The integrated support structure is put forward to improve rotation accuracy and operation stability of the UHSPMSM.Further,influence of the integrated support structure on critical speed is explored,and the key parameters such as support position and support stiffness are designed.Moreover,the rotor strength is analyzed by analytical model developed of rotor stress that can deal with multiple boundary types.Material and thickness of the sleeve are optimized,and range of interference value is accurately limited based on four extreme operating conditions.The 3-D Finite Element Model(FEM)is used to validate the strength characteristics and stress distribu-tion of rotor.A 1.5 kW-150000 r/min UHSPMSM with integrated support system is manufactured and tested.The feasibility of UHSPMSM proposed and the accuracy of analysis method are verified through electromagnetic,temperature rise and vibration characteristics test.The machine prototype realizes the load operation at rated speed and the multi-physical-field characteristics achieve the design specification.

Kinetic modeling of multiphase fow based on simplified Enskog equation

A new kinetic model for multiphase flow was presented under the framework of the discrete Boltzmann method(DBM).Significantly different from the previous DBM,a bottom-p approach was adopted in this model.The effects of molecular size and repulsion potential were described by the Enskog collision model;the attraction potential was obtained through the mean field approximation method.The molecular interactions,which result in the non-ideal equation of state and surface tension,were directly introduced as an external force term.Several typical benchmark problems,including Couette flow,two-phase coexistence curve,the Laplace law,phase separation,and the collision of two droplets,were simulated to verify the model.Especially,for two types of droplet collisions,the strengths of two non-equilibrium ffcts,D*2 and D*3,defined through the second and third order non-conserved kinetic moments of(f-feq),are comparatively investigated,where f(feq)is the(equilibrium)distribution function.It is interesting to find that during the collision process,D*2is always significantly larger than D*3,D*2 can be used to identify the different stages of the collision process and to distinguish different types of collisions.The modeling method can be directly extended to a higher.order model for the case where the non-equilibrium pffect is strong,and the linear constitutive law of viscous stress is no longer valid.

Characteristics Study of Weibo Users' Interactions

An individual＇s personal network is a basic object of study in sociology. This article analyzes and compares sina-weibo users＇ personal network size based on over 2 billion tweets gath- ered from over 1.3 million users in 2012. We propose a new measure method for the analysis of user interactions based on how an individual divides his attention across contacts and how user＇s characteristics affect the interactions. We find that the balance of attention of user with different age and gender is quite different in weibo. It displays interesting variation in both different groups of people and different modes of interaction.

Non-selfsimilar Global Solutions and Their Structure for the Multi-dimensional Combustion Models

We investigate the Chapman-Jouguet model in multi-dimensional space, and construct explicitly its non-selfsimilar Riemann solutions. By the method we apply in this paper, general initial discontinuities can be dealt with, even for complex interaction of combustion waves. Furthermore, we analyze the way in which the area of unburnt gas shrinks.