The rapid development of digital education provides new opportunities and challenges for teaching model innovation.This study aims to explore the application of the BOPPPS(Bridge-in,Objective,Pre-assessment,Participat...The rapid development of digital education provides new opportunities and challenges for teaching model innovation.This study aims to explore the application of the BOPPPS(Bridge-in,Objective,Pre-assessment,Participatory learning,Post-assessment,Summary)teaching method in the development of a blended teaching model for the Operations Research course under the background of digital education.In response to the characteristics of the course and the needs of the student group,the teaching design is reconstructed with a student-centered approach,increasing practical teaching links,improving the assessment and evaluation system,and effectively implementing it in conjunction with digital educational technology.This teaching model has shown significant effectiveness in the context of digital education,providing valuable experience and insights for the innovation of the Operations Research course.展开更多
Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July...Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July 2022 to May 2023 were randomly divided into two groups,32 cases in the control group and 32 cases in the intervention group.The control group was given conventional teaching methods,and the intervention group was given the bedside rhetorical teaching method on the basis of the conventional teaching.The differences in the methods of teaching between the two groups were compared after the end of the internship,and there was a statistically significant difference with P<0.05.Results:The scores of the interns in the intervention group were significantly better than those of the control group in theoretical knowledge,communication skills,and case analysis items(P<0.05).Conclusion:The bedside rhetorical teaching method transforms classroom education into bedside teaching,which enables the interns to apply the theoretical knowledge to clinical practice,and has a higher improvement in the three aspects of disease knowledge,communication skills,and case analysis,cultivates the interns’comprehensive clinical skills,and lays a good foundation for the future entry into the nursing field.展开更多
The achievement progresses of investigation and studies on marine hazardous geology are summarized and presentsd in the late 20 century in China. The importance, research value and present-day studies of marine hazard...The achievement progresses of investigation and studies on marine hazardous geology are summarized and presentsd in the late 20 century in China. The importance, research value and present-day studies of marine hazardous geology, a newly developing branch of geoscience, are well expatiated. Several often confused concepts and theories are explained and redefined here. The comment on the means of investigations, assessment of marine hazardous geology, as well as its evolution, innovation, existing questions and future tasks are also introduced and presented. The concepts of 'hazard geology', geohazard', 'map of marine hazard geology', 'integrated evaluaton on seafloor stablity' are respectively discussed, including their definition, research objects, methods and contents. The types and classification of marine hazardous geology, principles and methods of marine hazardous geology map compilation, the assessment methods and models of marine hazardous geology environment and seafloor stability and so on are also discussed.展开更多
The present paper first reviewed the major concepts and practices involves in research. A small study was conducted to survey on the prevailing research questions and methods in ELT studies in China, showing a major p...The present paper first reviewed the major concepts and practices involves in research. A small study was conducted to survey on the prevailing research questions and methods in ELT studies in China, showing a major paradigm shift from qualitative studies to quantitative research and mixed methods, with little critical research identified.展开更多
By reviewing the theories and methods of resource and environmental carrying capacity evaluation and suitability evaluation of land and space development,it provides theoretical and technical support for rational layo...By reviewing the theories and methods of resource and environmental carrying capacity evaluation and suitability evaluation of land and space development,it provides theoretical and technical support for rational layout and optimization of land and space development pattern.From the aspects of resource carrying capacity,environmental carrying capacity,the importance of ecological protection,the suitability of agricultural production,and the suitability of urban construction,we sort out domestic and foreign documents.The evaluation of resource carrying capacity has changed from single-factor evaluation to multi-factor comprehensive evaluation.At present,the optimization of land use pattern based on the“three-generation”space is still under exploration,it is not enough to systematize and summarize the thought of optimizing the spatial pattern of the national territory.The theoretical framework,model,method and index of“dual evaluation”of territorial space need to be improved continuously,it also needs the scientific analysis and cognition from the natural direction to the human location direction and the spatial equilibrium state as the new driving force.展开更多
Based on an extensive summary of existing literature together with a random sampling of 70 graduate theses at the author’s university and 30 papers submitted to journals,which the author was entrusted to review,the p...Based on an extensive summary of existing literature together with a random sampling of 70 graduate theses at the author’s university and 30 papers submitted to journals,which the author was entrusted to review,the present paper has addressed the novice researchers’common concern of research method application by defining and categorizing research methods and the related terms,combing and discussing the techniques for qualitative,quantitative,and mixed research methods in accordance with different research questions,and finally illustrating and explaining our viewpoints with real-life samples and comments.展开更多
Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors there...Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors therefore play a crucial role in defining the alternation of urban space--in particular, that of the centers. The main focus of this research article is on the methodology used in the survey and evaluation of "centralities" as well as their developments over the past four decades (1974-2014) in approaches to urban development that has been developed in Graz.~ The analysis has drawn on the four editions ("evolution") of approaches to urban development as conceived by the city of Graz in order to examine their verbal characteristics in regard to centralities. At the same time, the analysis does not examine presentations of plans which exist in supplementary forms (e.g., explanatory reports and supplemented plans)--it restricts itself solely to the various plans set out in the STEKs.2 The highest degree of accuracy has been applied to the notion of "centralis" in approaches to urban development. The goal of the research project was to depict the modulation of the notion of "centrality" in the urban context as a space-forming dimension. Furthermore, it clearly shows the extent to which the notion of the "centre" (in the widest sense of the word) has become distanced from qualitative, spatial development and at the current time of urban development is experiencing a sort of Renaissance. In the field of "urban development", architectural references in the context of"centrality" have scarcely been researched. This has led to the opening-up of a complex interdisciplinary research field. In order to make the complex architectural determinants of "centrality" more accessible to the participating disciplines, approaches to urban development have been explored in the form of a social and spatial analysis.展开更多
In the process of carrying out the teaching activities of the traditional physical education, due to the neglect of the effective integration of the psychological education, therefore, in the entire process of the phy...In the process of carrying out the teaching activities of the traditional physical education, due to the neglect of the effective integration of the psychological education, therefore, in the entire process of the physical education, there is a lack of the effective implementation of the psychological educational activities. Therefore, there is the phenomenon that some students cannot deal with the actual problems positively and optimistically, and especially their psychological quality is relatively weak, which has also brought great difficulties to the growth of their life, thus affecting the overall cultivation of the students. In this paper, from the analysis of the specific background of the innovative application of the methods and theories of the physical education, combined with the specific requirements on the concepts of the innovative education, the author explores the existing problems and shortcomings in the application process of the current sport teaching methods, so as to explore the specific ideas of the application of the methods and theories of the physical education under the idea of the creative education.展开更多
There are different ways to examine and explain a study and its findings based on using numbers as a measure,a descriptive style,or a mixture of both.These three research approaches are quantitative,qualitative,and mi...There are different ways to examine and explain a study and its findings based on using numbers as a measure,a descriptive style,or a mixture of both.These three research approaches are quantitative,qualitative,and mixed methods that are commonly used by researchers in various research studies.However,with many options regarding the research design,it seems challenging for researchers to select the most appropriate approach based on the study and realize differences.This study provides a comprehensive review of qualitative,quantitative,and mixed-method research methods.Each method is clearly defined and specifically discussed based on applications,types,advantages,and limitations to help researchers identify select the most relevant type based on each study and navigate accordingly.展开更多
Dongpu depression is a fault basin at residual-mobility period of Diwa stage, it developed on the strata of the Mesozoie and Pre-Mesozoie. It is one of the important oil/gas- bearing basin during Cenozoie era along th...Dongpu depression is a fault basin at residual-mobility period of Diwa stage, it developed on the strata of the Mesozoie and Pre-Mesozoie. It is one of the important oil/gas- bearing basin during Cenozoie era along the East China. The strueture in Dongpu geodepression is very complex. There exists a strueture pattern with east- and west-depression belts and one central swell belt, it is divided into the southern- and northern-division by Gaopingji (orMeng Ju ) -Xieheng fault.展开更多
Bupleurum has been used as traditional medicine in China,Japan,South Korea,and other Asian countries for more than 2,000 years.The crude extracts and pure compounds isolated from Bupleurum have a variety of biological...Bupleurum has been used as traditional medicine in China,Japan,South Korea,and other Asian countries for more than 2,000 years.The crude extracts and pure compounds isolated from Bupleurum have a variety of biological activities,such as anti-inflammatory,anti-cancer,antipyretic,antibacterial,anti-viral,liver protection,neuroprotection,and immune regxilation.The pharmacological effects of Bupleurum have been classified and summarized in this paper by consulting literatures at home and abroad.At the same time,the quality analysis methods of bupleurum,including high-performance liquid chromatography,thin layer chromatography,ultra-high-performance liquid chromatography mass spectrometry,UPLC-QTOF-MS,and so on,are discussed.This paper provides a reference for further research,development,and application of Bupleurum.展开更多
Gout is a metabolic bone and joint disease caused by purine metabolism disorder.The disturbance of inflammatory microenvironment caused by monosodium urate(MSU)deposition is an important pathological mechanism of gout...Gout is a metabolic bone and joint disease caused by purine metabolism disorder.The disturbance of inflammatory microenvironment caused by monosodium urate(MSU)deposition is an important pathological mechanism of gout occurrence and development.In the understanding of Traditional Chinese medicine(TCM),the interaction of"dampness","heat"and"stasis"is the main pathogenesis of gout,and the method of clearing heat and removing dampness is the main treatment method of TCM for gout.In recent years,studies have found that heat-clearing and dampness-removing method can improve the TCM symptom score of gout patients,especially in the body tiredness,dry mouth and dry throat,short yellow urine,thirsty,etc.,which are the characteristics of dampness and heat syndrome,this may be related to the fact that the TCM heat-clearing and dampness-removing method in the treatment of gout removes the appearance of dampness and heat,improves the inflammatory microenvironment of gout and restores the normal metabolic function of human body.This paper deeply explores the specific mechanism of TCM heat-clearing and dampness-removing method to improve the inflammatory microenvironment of gout,which can provide new ideas for the diagnosis and treatment of clinical gout.展开更多
Human is the subject of social and historical development process.The essence of human is the sum of social relations,and the masses are the creators of history.This is the basic content of social subject research met...Human is the subject of social and historical development process.The essence of human is the sum of social relations,and the masses are the creators of history.This is the basic content of social subject research methods,and also an important principle that must be followed by the subject category in ideology and politics education in colleges and universities.From the perspective of social subject research methods,the internal examination of the thought and politics education activities in colleges and universities should include three basic dimensions:adhering to examine the ideological and political moral construction activities via communicative practice,adhering to the principle of"all members,whole process and all dimensions(three-all principle)"to examine the"macro ideological and political"education concept,and adhering to the examination of the innovation of the ideology and politics education method system in higher education for the promotion of students’subjectivity.展开更多
So far, most theories of economics and management are under the same premisethat the natural resources are never exhausted and regenerated repeatedly. The magic of technologybrought by industrial revolution endowed hu...So far, most theories of economics and management are under the same premisethat the natural resources are never exhausted and regenerated repeatedly. The magic of technologybrought by industrial revolution endowed human with power that they can do anything they want. Italso turns natural resources into industrial energy and enhances the development of human societyand civilization. Human uses direct comparison of input and output and the satisfaction degree ofdemands to measure the production activities, the economic benefit and management performance,regardless of the change of ecology that serves as the natural resources. However, since theecological environment has been changing worse recently and natural disaster happened frequentlyhuman's dream of conquering the nature has been broken. The nature implements reprisal against humanagain and again, and human is faced with the development limit because of the environmentalrestriction.展开更多
In the research, changes of apple chemistry, and molecule, under stresses, are n terms of morphology, physiology, bio- illustrated and research and identifica- tion methods of apple resistance are explored involving ...In the research, changes of apple chemistry, and molecule, under stresses, are n terms of morphology, physiology, bio- illustrated and research and identifica- tion methods of apple resistance are explored involving drought-resistance, flood-re- sistance, salt-stress resistance, cold-hardiness and heat-resistance. In addition prospects of apple resistance research are proposed, as well.展开更多
consists of forecasting for the total reserves of regional mineral resources and evaluation,compreIn general,based on evaluated objects and factors involved,evaluation of mineral resources hensive evaluation of region...consists of forecasting for the total reserves of regional mineral resources and evaluation,compreIn general,based on evaluated objects and factors involved,evaluation of mineral resources hensive evaluation of regional mineral resources, and economic and technical evaluation of deposits. Here a region can be a country, a province, or a mining area, while a deposit is mainly related to a single type of mineral, although it can contain more than one types of minerals. In the past, to assess mineral resources was primarily to evaluate and forecast the total reserves of regional mineral resources. With the advancement of science, technology, and economy, the evaluation of mineral resources has developed from forecasting the reserves of them to comprehensively evaluating them on the basis of numerous factors.展开更多
Microplastics are plastic particles or fibers with a diameter of less than 5 mm,and they widely exist in the environment and pose potential risks to the ecosystem and human health.Microplastics detection can provide b...Microplastics are plastic particles or fibers with a diameter of less than 5 mm,and they widely exist in the environment and pose potential risks to the ecosystem and human health.Microplastics detection can provide basic data for formulating effective environmental protection strategies.In this paper,the physical,chemical and biological detection methods of microplastics are reviewed,and the advantages and disadvantages of different methods are analyzed.The problems and challenges encountered in microplastics detection are analyzed,and the future research is discussed.展开更多
Background:The number of medical research publications by Chinese clinical investigators has risen substantially,contributing to 14.63%of the global total in 2019;however,their tangible impact on clinical decisionmaki...Background:The number of medical research publications by Chinese clinical investigators has risen substantially,contributing to 14.63%of the global total in 2019;however,their tangible impact on clinical decisionmaking remains limited.Various evaluation methods have been developed to measure hospital research competence in China,such as Fudan University's China hospital ranking and Science and Technology Evaluation Metrics(STEM)ranking,which predominantly focuses on factors such as academic reputation,volume of publications and patents,and research resources.However,composite indices may not fully capture the actual clinical value generated by medical research.To address this gap,we introduced the“Clinical Influence and Timeliness Evaluation(CITE)”metric to assess both the clinical importance of a given medical research study and the clinical influence of the hospital where it originated.The methodology used relies on the premise that influential medical research would be referenced in clinical guidelines,which serve as critical resources for clinicians.Methods:The CITE metric was applied for 78,636 medical studies concerning chronic obstructive pulmonary disease(COPD)published between 2000 and 2020 and referenced in both Chinese and international clinical guidelines for COPD.Specific indexes and formulas were derived to quantify the clinical weight of a medical research study(W)and its timeliness(T),enabling a dynamic assessment of the clinical value of each study and the overall contribution of a particular hospital.Results:In this analysis,we incorporated 499 hospitals in China and quantitatively identified their dynamic clinical influence in COPD from 2000 to 2020.Our findings offer objective and targeted evaluation metrics by focusing on clinical relevance and recognizing the collaborative nature of medical research.Conclusion:The CITE metric provides an innovative method to gauge the true impact of medical research in China,with potential applications across different medical specialties.CITE can serve as a useful tool for understanding the relationship between research input and practical clinical outcomes,ultimately promoting more clinically relevant research endeavors.展开更多
Interviewing is one of the most common and most powerful research methods in sociology. To provide an overview of interviewing in social research, the preliminaries and some tactics applied in interviewing are illustr...Interviewing is one of the most common and most powerful research methods in sociology. To provide an overview of interviewing in social research, the preliminaries and some tactics applied in interviewing are illustrated firstly. Secondly, various forms of interviewing employed in social research are analyzed specifically. Finally, the issues of interviewing are critically examined.展开更多
AIMTo describe the development and validation of a novel neuronavigation-based method, which allows the quan-tification of the anatomical features that define anapproach, as well as real-time visualization of the surg...AIMTo describe the development and validation of a novel neuronavigation-based method, which allows the quan-tification of the anatomical features that define anapproach, as well as real-time visualization of the surgicapyramid. METHODSThe method was initially developed with commercially-available hardware for coordinate collection (a digitizerand a frameless navigation system) and software forvolume rendering; dedicated neuronavigation software (ApproachViewer, part of GTx-UHN) was then developed. The accuracy of measurements and the possibility of volumetric rendering of surgical approaches simulated in a phantom were compared among three different methods and commercially-available radiological software. In the anatomy laboratory, ApproachViewer was applied to the comparative quantitative analysis of multiple neurosurgical approaches and was used by many surgeons who were untrained for the research method.RESULTSThe accuracy of ApproachViewer is comparable to com-mercially-available radiological software. In the anatomy laboratory, the method appears versatile. The system can be easily used after brief training. ApproachViewer allows for real-time evaluation and comparison of surgical approaches, as well as post-dissection analyses of collected data. The accuracy of the method depends on the navigation registration: with a 1-2 mm registration error, it is adequate for evaluation and comparison of most neurosurgical approaches.CONCLUSIONThis new research method and software allows semi-automated visualization, quantifcation, and comparison of neurosurgical approaches in the anatomy laboratory.展开更多
文摘The rapid development of digital education provides new opportunities and challenges for teaching model innovation.This study aims to explore the application of the BOPPPS(Bridge-in,Objective,Pre-assessment,Participatory learning,Post-assessment,Summary)teaching method in the development of a blended teaching model for the Operations Research course under the background of digital education.In response to the characteristics of the course and the needs of the student group,the teaching design is reconstructed with a student-centered approach,increasing practical teaching links,improving the assessment and evaluation system,and effectively implementing it in conjunction with digital educational technology.This teaching model has shown significant effectiveness in the context of digital education,providing valuable experience and insights for the innovation of the Operations Research course.
文摘Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July 2022 to May 2023 were randomly divided into two groups,32 cases in the control group and 32 cases in the intervention group.The control group was given conventional teaching methods,and the intervention group was given the bedside rhetorical teaching method on the basis of the conventional teaching.The differences in the methods of teaching between the two groups were compared after the end of the internship,and there was a statistically significant difference with P<0.05.Results:The scores of the interns in the intervention group were significantly better than those of the control group in theoretical knowledge,communication skills,and case analysis items(P<0.05).Conclusion:The bedside rhetorical teaching method transforms classroom education into bedside teaching,which enables the interns to apply the theoretical knowledge to clinical practice,and has a higher improvement in the three aspects of disease knowledge,communication skills,and case analysis,cultivates the interns’comprehensive clinical skills,and lays a good foundation for the future entry into the nursing field.
文摘The achievement progresses of investigation and studies on marine hazardous geology are summarized and presentsd in the late 20 century in China. The importance, research value and present-day studies of marine hazardous geology, a newly developing branch of geoscience, are well expatiated. Several often confused concepts and theories are explained and redefined here. The comment on the means of investigations, assessment of marine hazardous geology, as well as its evolution, innovation, existing questions and future tasks are also introduced and presented. The concepts of 'hazard geology', geohazard', 'map of marine hazard geology', 'integrated evaluaton on seafloor stablity' are respectively discussed, including their definition, research objects, methods and contents. The types and classification of marine hazardous geology, principles and methods of marine hazardous geology map compilation, the assessment methods and models of marine hazardous geology environment and seafloor stability and so on are also discussed.
文摘The present paper first reviewed the major concepts and practices involves in research. A small study was conducted to survey on the prevailing research questions and methods in ELT studies in China, showing a major paradigm shift from qualitative studies to quantitative research and mixed methods, with little critical research identified.
基金This paper is supported by National Natural Science Foundation of China(Grant Nos.41661109,4261043)Guangxi Science and Technology Base and Talent Special Project(Grant No.Guike AD19245041)Nanning Normal University Doctoral Research Project(Grant No.0819-2019L07).
文摘By reviewing the theories and methods of resource and environmental carrying capacity evaluation and suitability evaluation of land and space development,it provides theoretical and technical support for rational layout and optimization of land and space development pattern.From the aspects of resource carrying capacity,environmental carrying capacity,the importance of ecological protection,the suitability of agricultural production,and the suitability of urban construction,we sort out domestic and foreign documents.The evaluation of resource carrying capacity has changed from single-factor evaluation to multi-factor comprehensive evaluation.At present,the optimization of land use pattern based on the“three-generation”space is still under exploration,it is not enough to systematize and summarize the thought of optimizing the spatial pattern of the national territory.The theoretical framework,model,method and index of“dual evaluation”of territorial space need to be improved continuously,it also needs the scientific analysis and cognition from the natural direction to the human location direction and the spatial equilibrium state as the new driving force.
文摘Based on an extensive summary of existing literature together with a random sampling of 70 graduate theses at the author’s university and 30 papers submitted to journals,which the author was entrusted to review,the present paper has addressed the novice researchers’common concern of research method application by defining and categorizing research methods and the related terms,combing and discussing the techniques for qualitative,quantitative,and mixed research methods in accordance with different research questions,and finally illustrating and explaining our viewpoints with real-life samples and comments.
文摘Dispersed and peripheral spaces in the urban core are influenced both by the trend towards constant growth as well as social ways of life which are constantly evolving. Following a connotation, these two factors therefore play a crucial role in defining the alternation of urban space--in particular, that of the centers. The main focus of this research article is on the methodology used in the survey and evaluation of "centralities" as well as their developments over the past four decades (1974-2014) in approaches to urban development that has been developed in Graz.~ The analysis has drawn on the four editions ("evolution") of approaches to urban development as conceived by the city of Graz in order to examine their verbal characteristics in regard to centralities. At the same time, the analysis does not examine presentations of plans which exist in supplementary forms (e.g., explanatory reports and supplemented plans)--it restricts itself solely to the various plans set out in the STEKs.2 The highest degree of accuracy has been applied to the notion of "centralis" in approaches to urban development. The goal of the research project was to depict the modulation of the notion of "centrality" in the urban context as a space-forming dimension. Furthermore, it clearly shows the extent to which the notion of the "centre" (in the widest sense of the word) has become distanced from qualitative, spatial development and at the current time of urban development is experiencing a sort of Renaissance. In the field of "urban development", architectural references in the context of"centrality" have scarcely been researched. This has led to the opening-up of a complex interdisciplinary research field. In order to make the complex architectural determinants of "centrality" more accessible to the participating disciplines, approaches to urban development have been explored in the form of a social and spatial analysis.
文摘In the process of carrying out the teaching activities of the traditional physical education, due to the neglect of the effective integration of the psychological education, therefore, in the entire process of the physical education, there is a lack of the effective implementation of the psychological educational activities. Therefore, there is the phenomenon that some students cannot deal with the actual problems positively and optimistically, and especially their psychological quality is relatively weak, which has also brought great difficulties to the growth of their life, thus affecting the overall cultivation of the students. In this paper, from the analysis of the specific background of the innovative application of the methods and theories of the physical education, combined with the specific requirements on the concepts of the innovative education, the author explores the existing problems and shortcomings in the application process of the current sport teaching methods, so as to explore the specific ideas of the application of the methods and theories of the physical education under the idea of the creative education.
文摘There are different ways to examine and explain a study and its findings based on using numbers as a measure,a descriptive style,or a mixture of both.These three research approaches are quantitative,qualitative,and mixed methods that are commonly used by researchers in various research studies.However,with many options regarding the research design,it seems challenging for researchers to select the most appropriate approach based on the study and realize differences.This study provides a comprehensive review of qualitative,quantitative,and mixed-method research methods.Each method is clearly defined and specifically discussed based on applications,types,advantages,and limitations to help researchers identify select the most relevant type based on each study and navigate accordingly.
文摘Dongpu depression is a fault basin at residual-mobility period of Diwa stage, it developed on the strata of the Mesozoie and Pre-Mesozoie. It is one of the important oil/gas- bearing basin during Cenozoie era along the East China. The strueture in Dongpu geodepression is very complex. There exists a strueture pattern with east- and west-depression belts and one central swell belt, it is divided into the southern- and northern-division by Gaopingji (orMeng Ju ) -Xieheng fault.
文摘Bupleurum has been used as traditional medicine in China,Japan,South Korea,and other Asian countries for more than 2,000 years.The crude extracts and pure compounds isolated from Bupleurum have a variety of biological activities,such as anti-inflammatory,anti-cancer,antipyretic,antibacterial,anti-viral,liver protection,neuroprotection,and immune regxilation.The pharmacological effects of Bupleurum have been classified and summarized in this paper by consulting literatures at home and abroad.At the same time,the quality analysis methods of bupleurum,including high-performance liquid chromatography,thin layer chromatography,ultra-high-performance liquid chromatography mass spectrometry,UPLC-QTOF-MS,and so on,are discussed.This paper provides a reference for further research,development,and application of Bupleurum.
文摘Gout is a metabolic bone and joint disease caused by purine metabolism disorder.The disturbance of inflammatory microenvironment caused by monosodium urate(MSU)deposition is an important pathological mechanism of gout occurrence and development.In the understanding of Traditional Chinese medicine(TCM),the interaction of"dampness","heat"and"stasis"is the main pathogenesis of gout,and the method of clearing heat and removing dampness is the main treatment method of TCM for gout.In recent years,studies have found that heat-clearing and dampness-removing method can improve the TCM symptom score of gout patients,especially in the body tiredness,dry mouth and dry throat,short yellow urine,thirsty,etc.,which are the characteristics of dampness and heat syndrome,this may be related to the fact that the TCM heat-clearing and dampness-removing method in the treatment of gout removes the appearance of dampness and heat,improves the inflammatory microenvironment of gout and restores the normal metabolic function of human body.This paper deeply explores the specific mechanism of TCM heat-clearing and dampness-removing method to improve the inflammatory microenvironment of gout,which can provide new ideas for the diagnosis and treatment of clinical gout.
文摘Human is the subject of social and historical development process.The essence of human is the sum of social relations,and the masses are the creators of history.This is the basic content of social subject research methods,and also an important principle that must be followed by the subject category in ideology and politics education in colleges and universities.From the perspective of social subject research methods,the internal examination of the thought and politics education activities in colleges and universities should include three basic dimensions:adhering to examine the ideological and political moral construction activities via communicative practice,adhering to the principle of"all members,whole process and all dimensions(three-all principle)"to examine the"macro ideological and political"education concept,and adhering to the examination of the innovation of the ideology and politics education method system in higher education for the promotion of students’subjectivity.
文摘So far, most theories of economics and management are under the same premisethat the natural resources are never exhausted and regenerated repeatedly. The magic of technologybrought by industrial revolution endowed human with power that they can do anything they want. Italso turns natural resources into industrial energy and enhances the development of human societyand civilization. Human uses direct comparison of input and output and the satisfaction degree ofdemands to measure the production activities, the economic benefit and management performance,regardless of the change of ecology that serves as the natural resources. However, since theecological environment has been changing worse recently and natural disaster happened frequentlyhuman's dream of conquering the nature has been broken. The nature implements reprisal against humanagain and again, and human is faced with the development limit because of the environmentalrestriction.
基金Supported by Shandong Provincial Natural Science Foundation in China(ZR2011CM034)~~
文摘In the research, changes of apple chemistry, and molecule, under stresses, are n terms of morphology, physiology, bio- illustrated and research and identifica- tion methods of apple resistance are explored involving drought-resistance, flood-re- sistance, salt-stress resistance, cold-hardiness and heat-resistance. In addition prospects of apple resistance research are proposed, as well.
文摘consists of forecasting for the total reserves of regional mineral resources and evaluation,compreIn general,based on evaluated objects and factors involved,evaluation of mineral resources hensive evaluation of regional mineral resources, and economic and technical evaluation of deposits. Here a region can be a country, a province, or a mining area, while a deposit is mainly related to a single type of mineral, although it can contain more than one types of minerals. In the past, to assess mineral resources was primarily to evaluate and forecast the total reserves of regional mineral resources. With the advancement of science, technology, and economy, the evaluation of mineral resources has developed from forecasting the reserves of them to comprehensively evaluating them on the basis of numerous factors.
文摘Microplastics are plastic particles or fibers with a diameter of less than 5 mm,and they widely exist in the environment and pose potential risks to the ecosystem and human health.Microplastics detection can provide basic data for formulating effective environmental protection strategies.In this paper,the physical,chemical and biological detection methods of microplastics are reviewed,and the advantages and disadvantages of different methods are analyzed.The problems and challenges encountered in microplastics detection are analyzed,and the future research is discussed.
文摘Background:The number of medical research publications by Chinese clinical investigators has risen substantially,contributing to 14.63%of the global total in 2019;however,their tangible impact on clinical decisionmaking remains limited.Various evaluation methods have been developed to measure hospital research competence in China,such as Fudan University's China hospital ranking and Science and Technology Evaluation Metrics(STEM)ranking,which predominantly focuses on factors such as academic reputation,volume of publications and patents,and research resources.However,composite indices may not fully capture the actual clinical value generated by medical research.To address this gap,we introduced the“Clinical Influence and Timeliness Evaluation(CITE)”metric to assess both the clinical importance of a given medical research study and the clinical influence of the hospital where it originated.The methodology used relies on the premise that influential medical research would be referenced in clinical guidelines,which serve as critical resources for clinicians.Methods:The CITE metric was applied for 78,636 medical studies concerning chronic obstructive pulmonary disease(COPD)published between 2000 and 2020 and referenced in both Chinese and international clinical guidelines for COPD.Specific indexes and formulas were derived to quantify the clinical weight of a medical research study(W)and its timeliness(T),enabling a dynamic assessment of the clinical value of each study and the overall contribution of a particular hospital.Results:In this analysis,we incorporated 499 hospitals in China and quantitatively identified their dynamic clinical influence in COPD from 2000 to 2020.Our findings offer objective and targeted evaluation metrics by focusing on clinical relevance and recognizing the collaborative nature of medical research.Conclusion:The CITE metric provides an innovative method to gauge the true impact of medical research in China,with potential applications across different medical specialties.CITE can serve as a useful tool for understanding the relationship between research input and practical clinical outcomes,ultimately promoting more clinically relevant research endeavors.
文摘Interviewing is one of the most common and most powerful research methods in sociology. To provide an overview of interviewing in social research, the preliminaries and some tactics applied in interviewing are illustrated firstly. Secondly, various forms of interviewing employed in social research are analyzed specifically. Finally, the issues of interviewing are critically examined.
基金Supported by Fondazione"Giuseppe Alazio",via Torquato Tasso,22,90144 Palermo,Italy(to Doglietto F)
文摘AIMTo describe the development and validation of a novel neuronavigation-based method, which allows the quan-tification of the anatomical features that define anapproach, as well as real-time visualization of the surgicapyramid. METHODSThe method was initially developed with commercially-available hardware for coordinate collection (a digitizerand a frameless navigation system) and software forvolume rendering; dedicated neuronavigation software (ApproachViewer, part of GTx-UHN) was then developed. The accuracy of measurements and the possibility of volumetric rendering of surgical approaches simulated in a phantom were compared among three different methods and commercially-available radiological software. In the anatomy laboratory, ApproachViewer was applied to the comparative quantitative analysis of multiple neurosurgical approaches and was used by many surgeons who were untrained for the research method.RESULTSThe accuracy of ApproachViewer is comparable to com-mercially-available radiological software. In the anatomy laboratory, the method appears versatile. The system can be easily used after brief training. ApproachViewer allows for real-time evaluation and comparison of surgical approaches, as well as post-dissection analyses of collected data. The accuracy of the method depends on the navigation registration: with a 1-2 mm registration error, it is adequate for evaluation and comparison of most neurosurgical approaches.CONCLUSIONThis new research method and software allows semi-automated visualization, quantifcation, and comparison of neurosurgical approaches in the anatomy laboratory.