Monnclonal antibody HMB-45 was previously thought to be melanoma specific antibody and was taken recently as a marker for melanocyte proliferation or activation. A single UV-irradiation system which may induce a funct...Monnclonal antibody HMB-45 was previously thought to be melanoma specific antibody and was taken recently as a marker for melanocyte proliferation or activation. A single UV-irradiation system which may induce a functional activity change in melanocytes was used to test the irradiated epidermal melanocyte for expression of HMB-45.Melanocytes, in the epidermis of the biopsies taken 7 days after a single UV exposure, showed markedly stained HMB-45,accompanied by morphological changes such as enlarged size,rich cytoplasma and elongated dendrites. We conclude that since morphological changes in irradiated melanocytes may be interpreted as signs of functional activity changes, melanocytes are exposed to sthnulatory factors induced by UV light and get into a functional activating state to produce melanosome and HMB-45 antigen. Besides, the presence of HMB-45 in a single UV exposed epidermal melanocyte may support the hypothesis that its expression is inducible and is closely related to the functional activity展开更多
A method, called Two-Dimensional Extended Attribute Grammars (2-DEAGs). for the recognition of hand-printed Chinese characters is presented. This method uses directly two dimensional information, and pro- vides a sche...A method, called Two-Dimensional Extended Attribute Grammars (2-DEAGs). for the recognition of hand-printed Chinese characters is presented. This method uses directly two dimensional information, and pro- vides a scheme for dealing with various kinds of specific cases in a uniform way. In this method, components are drawn in guided and redundant way and reductions are made level by level just in accordance with the com- ponent combination relations of Chinese characters. The method provides also polysemous grammars, coexisting grammars and structure inferrings which constrain redundant recognition by comparison among similar characters or components and greatly increase the tolerance ability to distortion.展开更多
文摘Monnclonal antibody HMB-45 was previously thought to be melanoma specific antibody and was taken recently as a marker for melanocyte proliferation or activation. A single UV-irradiation system which may induce a functional activity change in melanocytes was used to test the irradiated epidermal melanocyte for expression of HMB-45.Melanocytes, in the epidermis of the biopsies taken 7 days after a single UV exposure, showed markedly stained HMB-45,accompanied by morphological changes such as enlarged size,rich cytoplasma and elongated dendrites. We conclude that since morphological changes in irradiated melanocytes may be interpreted as signs of functional activity changes, melanocytes are exposed to sthnulatory factors induced by UV light and get into a functional activating state to produce melanosome and HMB-45 antigen. Besides, the presence of HMB-45 in a single UV exposed epidermal melanocyte may support the hypothesis that its expression is inducible and is closely related to the functional activity
基金Supported by the National Natural Science Foundation of China,No.6883024.
文摘A method, called Two-Dimensional Extended Attribute Grammars (2-DEAGs). for the recognition of hand-printed Chinese characters is presented. This method uses directly two dimensional information, and pro- vides a scheme for dealing with various kinds of specific cases in a uniform way. In this method, components are drawn in guided and redundant way and reductions are made level by level just in accordance with the com- ponent combination relations of Chinese characters. The method provides also polysemous grammars, coexisting grammars and structure inferrings which constrain redundant recognition by comparison among similar characters or components and greatly increase the tolerance ability to distortion.
