Supplementation of vitamin E or a botanical extract as antioxidants to improve growth performance and health of growing pigs housed under thermoneutral or heat-stressed conditions

Background Heat stress has severe negative consequences on performance and health of pigs,leading to significant economic losses.The objective of this study was to investigate the effects of supplemental vitamin E and a botanical extract in feed or drinking water on growth performance,intestinal health,and oxidative and immune status in grow-ing pigs housed under heat stress conditions.Methods Duplicate experiments were conducted,each using 64 crossbred pigs with an initial body weight of 50.7±3.8 and 43.9±3.6 kg and age of 13-week and 12-week,respectively.Pigs(n=128)were housed individually and assigned within weight blocks and sex to a 2×4 factorial arrangement consisting of 2 environments(thermo-neutral(21.2℃)or heat-stressed(30.9℃))and 4 supplementation treatments(control diet;control+100 IU/L of D-α-tocopherol in water;control+200 IU/kg of DL-α-tocopheryl-acetate in feed;or control+400 mg/kg of a botanical extract in feed).Results Heat stress for 28 d reduced(P≤0.001)final body weight,average daily gain,and average daily feed intake(-7.4 kg,-26.7%,and-25.4%,respectively)but no effects of supplementation were detected(P>0.05).Serum vitamin E increased(P<0.001)with vitamin E supplementation in water and in feed(1.64 vs.3.59 and 1.64 vs.3.24),but not for the botanical extract(1.64 vs.1.67 mg/kg)and was greater when supplemented in water vs.feed(P=0.002).Liver vitamin E increased(P<0.001)with vitamin E supplementations in water(3.9 vs.31.8)and feed(3.9 vs.18.0),but not with the botanical extract(3.9 vs.4.9 mg/kg).Serum malondialdehyde was reduced with heat stress on d 2,but increased on d 28(interaction,P<0.001),and was greater(P<0.05)for antioxidant supplementation compared to control.Cellular proliferation was reduced(P=0.037)in the jejunum under heat stress,but increased in the ileum when vitamin E was supplemented in feed and water under heat stress(interaction,P=0.04).Tumor necrosis factor-αin jejunum and ileum mucosa decreased by heat stress(P<0.05)and was reduced by vitamin E sup-plementations under heat stress(interaction,P<0.001).Conclusions The addition of the antioxidants in feed or in drinking water did not alleviate the negative impact of heat stress on feed intake and growth rate of growing pigs.

Changes of China’s Status in the Global System and Its Influencing Factors:A Multiple Contact Networks Perspective

Clarifying China’s position in the global system is an important logical basis for developing national diplomacy.Although much research has been done on China’s development status,most studies have been based on country comparisons or institutional en-vironment.In today’s networked era in which the global economy,trade,personnel,and information are closely connected,studies on China’s global position and its status changes and influencing factors in multiple contact networks are still insufficient.In this study,from the perspective of diverse global contact networks,we constructed economic,cultural,and political influence indices to explore the changes and influencing factors on China’s status in the global system from 2005 to 2018.The results show that during the study period,China’s global influence in the fields of economic ties,cultural exchanges,and political contacts increased significantly,but its influ-ence in the fields of cultural exchanges and political contacts lagged far economic ties.The pattern of China’s economic influence on various economies around the world has shown a transformation from an‘upright pyramid’to an‘inverted pyramid’structure.The proportion of these economies in low-influence zones has decreased from more than 60%in 2005 to less than 20%in 2018.China’s cultural and political influence on various economies around the world has increased significantly;however,for the former,the percentage of high-influence areas is still less than 20%,whereas for the latter the percentage of these economies in medium-and high-influence areas is still less than 50%.Analyses such as a scatter plot matrix show that geographical proximity,economic globalization,close cooperation with developing countries,and a proactive and peaceful foreign policy are important factors in improving China’s status in the diverse global network system.

The Conflict between Individuals and Society in Seize the Day

This paper explores the existential problem in Seize the Day-the conflict between individuals and society in modern society.With a brief introduction of Saul Bellow and the novel,the paper emphasizes the analysis of the conflict and the sources of the conflict.Besides,Saul Bellow uses many rhetorical devices to intensify the conflict.The analysis of these rhetorical devices is beneficial for us to interpret and understand the true meaning of the novel.Through the study of Bellow’s vision and the novel’s metaphorical meaning,we may find an effective solution to the conflict that our human being is involved in,and realize the social values of this novel.

Antibody Levels and Infection Status of Pertussis in the Population under Pertussis Resurgence in Guangxi in 2018:A Cross-Sectional Survey

Objective Pertussis cases have increased markedly since 2018 in Guangxi.The aim of this study was to evaluate antibody levels and the infection status of pertussis in the resident population.Method A total of 10,215 serum samples from residents were collected from August-November 2018 and tested for anti-pertussis IgG and toxin IgG using the enzyme-linked immunosorbent assay(ELISA).Results Of the collected samples,1,833(17.94%)tested positive for anti-pertussis IgG,with the median concentration of 16.06 IU/mL.Antibody level<10 IU/mL accounted for more than 60%in children under 4 years of age,but declined with age,whereas the percentages of the other three levels(10-40,40-50,and≥50 IU/mL)increased almost with age(P<0.001).Moreover,7,924 samples were selected for anti-pertussis toxin IgG,of which 653(8.24%)tested positive(≥40 IU/mL)with the median concentration of 5.89 IU/mL,and 204 participants(2.56%)had recent pertussis infection(≥100 IU/mL).Among the different age groups,the highest rates of positivity and recent infection were observed at 11-20 years of age,the lowest positivity rate at 5 years of age,and the lowest recent infection rate at 4 years of age(P<0.001,P=0.005,respectively).Conclusion The survey results showed that all age groups in Guangxi lacked immunity against pertussis,which was one of the main factors contributing to the resurgence of pertussis in 2018.In addition,the prevalence of pertussis is relatively high in Guangxi,and its incidence is seriously underestimated,especially in adolescents and adults.

Effects of intensive psychological intervention on treatment compliance,psychological status,and quality of life of patients with epilepsy

BACKGROUND Epilepsy is a nervous system disease characterized by recurrent attacks,a long disease course,and an unfavorable prognosis.It is associated with an enduring therapeutic process,and finding a cure has been difficult.Patients with epilepsy are predisposed to adverse moods,such as resistance,anxiety,nervousness,and anxiety,which compromise treatment compliance and overall efficacy.AIM To explored the influence of intensive psychological intervention on treatment compliance,psychological status,and quality of life(QOL)of patients with epilepsy.METHODS The clinical data of 105 patients with epilepsy admitted between December 2019 and July 2023 were retrospectively analyzed,including those of 50 patients who underwent routine intervention(control group)and 55 who underwent intensive psychological intervention(research group).Treatment compliance,psychological status based on the Self-Rating Anxiety Scale(SAS)and Depression Scale Self-Rating Depression Scale(SDS)scores,hope level assessed using the Herth Hope Scale(HHS),psychological resilience evaluated using the Psychological Resilience Scale,and QOL determined using the QOL in Epilepsy-31 Inventory(QOLIE-31)were comparatively analyzed.RESULTS Treatment compliance in the research group was 85.5%,which is significantly better than the 68.0%of the control group.No notable intergroup differences in preinterventional SAS and SDS scores were identified(P>0.05);however,after the intervention,the SAS and SDS scores decreased significantly in the two groups,especially in the research group(P<0.05).The two groups also exhibited no significant differences in preinterventional HHS,Connor-Davidson Resilience Scale(CD-RISC),and QOLIE-31 scores(P>0.05).After 6 months of intervention,the research group showed evidently higher HHS,CD-RISC,tenacity,optimism,strength,and QOLIE-31 scores(P<0.05).CONCLUSION Intensive psychological intervention enhances treatment compliance,psychological status,and QOL of patients with epilepsy.

Investigation and Analysis of Main Diseases of Landscape Plants in the Main Urban Area of Lu'an City

To figure out the disease occurrence of landscape plants in the main urban area of Lu'an City,the author investigated the disease occurrence of landscape plants in park green space,residential green space,unit attached green space and main road in the area under administration.The survey results showed that there were 29 species of urban landscape plant diseases,mainly powdery mildew and spot diseases.According to the characteristics of the diseases,the causes and problems of the diseases were analyzed,and the corresponding prevention and control measures were put forward.

Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study

BACKGROUND Previous observational studies have shown that the prevalence of gastroesophageal reflux disease(GERD)and Barrett’s esophagus(BE)is associated with socioeconomic status.However,due to the methodological limitations of traditional observational studies,it is challenging to definitively establish causality.AIM To explore the causal relationship between the prevalence of these conditions and socioeconomic status using Mendelian randomization(MR).METHODS We initially screened single nucleotide polymorphisms(SNPs)to serve as proxies for eight socioeconomic status phenotypes for univariate MR analysis.The inverse variance weighted(IVW)method was used as the primary analytical method to estimate the causal relationship between the eight socioeconomic status phenotypes and the risk of GERD and BE.We then collected combinations of SNPs as composite proxies for the eight socioeconomic phenotypes to perform multivariate MR(MVMR)analyses based on the IVW MVMR model.Furthermore,a two-step MR mediation analysis was used to examine the potential mediation of the associations by body mass index,major depressive disorder(MDD),smoking,alcohol consumption,and sleep duration.RESULTS The study identified three socioeconomic statuses that had a significant impact on GERD.These included household income[odds ratio(OR):0.46;95% confidence interval(95%CI):0.31-0.70],education attainment(OR:0.23;95%CI:0.18-0.29),and the Townsend Deprivation Index at recruitment(OR:1.57;95%CI:1.04-2.37).These factors were found to independently and predominantly influence the genetic causal effect of GERD.Furthermore,the mediating effect of educational attainment on GERD was found to be mediated by MDD(proportion mediated:10.83%).Similarly,the effect of educational attainment on BE was mediated by MDD(proportion mediated:10.58%)and the number of cigarettes smoked per day(proportion mediated:3.50%).Additionally,the mediating effect of household income on GERD was observed to be mediated by sleep duration(proportion mediated:9.75%)CONCLUSION This MR study shed light on the link between socioeconomic status and GERD or BE,providing insights for the prevention of esophageal cancer and precancerous lesions.

Status Quo Bias-A Research on Its Applications and the Correlating Mechanism

After several former studies on the cognitive heuristics and correlating economical influences,the explanatory effectiveness of Status Quo Bias perspective is explained by multiple empirical scenarios.Hence,this essay will focus on three applications in which the Status Quo Bias perspective,correlating models,and research methods would provide insightful opinions.After reviewing the former attempts on the original model and early researchers’empirical examination on the Status Quo Bias,this essay will concentrate on Status Quo Bias and technology resistance among the public sector employees,Status Quo Bias and medical insurance outcomes,Status Quo Bias and shoppers’mobile website purchasing resistance respectively.For each application,research methodology will be explained and be integrated into the Status Quo Bias perspective through the research question.Through researching on these applications’methodology and main studies,discussing cognitive biases existing in the empirical scenarios,the present study could approach to the efficiency of the explanation from Status Quo Bias perspective.

Correlation between DKK-1 Level and Bone Density Status in Children on Maintenance Haemodialysis

Background: Renal osteodystrophy (ROD) is a bone disorder resulting from chronic kidney disease (CKD) and related metabolic diseases. Dickkopf-related protein-1 (DKK-1) is critical in regulating bone biology. This study aimed to evaluate the serum DKK-1 level as a bone marker in children with CKD who undergo regular hemodialysis (HD). Subjects and Methods: This case-control study involved 40 children with CKD on HD and 40 healthy children as controls. The study measured serum DKK-1 levels and performed a dual-energy X-ray absorptiometry scan (DEXA) in line with routine laboratory investigations. Results: There was a significant increase in the serum level of DKK-1 in the patient group compared to the control group. The DKK-1 levels were 2540.65 (2215.4 - 2909.2) pg/ml and 1110.45 (885.45 - 1527.65) pg/ml, respectively, with a p-value of less than 0.001. In the hemodialysis group, 25 patients (62.5%) had low bone mineral density (BMD) with a Z-score of under -2.0. Eighteen of these patients had low BMD in both the neck of the femur and lumbar spines. Additionally, there was a significant increase in serum DKK-1 level in patients with low BMD (2567.35 (2303.8 - 3108.1) pg/ml) compared to patients with normal BMD (2454 (1859 - 2820) pg/ml) (p = 0.041). There was also a significant positive correlation between DKK1 level and phosphorus, alkaline phosphatase, and Parathormone serum levels. In conclusion, the study indicates a clear correlation between DKK-1 and BMD in children undergoing maintenance hemodialysis. DKK1 is a promising biomarker for CKD-MBD.

Growth, Population Parameters and Stock Status of Sarotherodon galilaeus in Samandeni Reservoir, Burkina Faso

Mango tilapia, Sarotherodon galilaeus is one of the most caught fish species in the Samandeni multi-species fishing sites of which, few data on its biology and exploitation are available. The study aimed to Assess the stock status of S. galilaeus. Sampling was conducted from March, 2021 to February 2022 based on commercial fish catches to analyze growth parameters, first sexual maturity size and harvest status of the stock. A total of 572 specimens including 297 females and 275 males were examined. The stock assessment was performed by using the Length based Bayesian method of Biomass (LBB) and that of growth by the ELEFAN method. The growth parameters showed a seasonality of growth and females appeared to grow faster than males. On the other hand, males had a greater asymptotic length than females. Results on the estimated length of fish at first maturity showed that females firstly reached the maturity compared to males. The relative biomass (B/B0) estimated for the stock was higher than the relative biomass that produces maximum sustainable yield (BMSY/B0) indicating healthy biomass. In addition, the length at first sexual maturity was less than the length at the first catch, indicating the absence of overfishing of growth. In addition, extending the study to the various stocks of the reservoir would be important for the sustainable management of the Samandeni high economic fishing area.

The Current Conservation Efforts and Future Prospects for the Endangered Nubian Ibex (Capra nubiana ibex) in Sudan

A comprehensive action plan for the conservation of the endangered species, the Nubian ibex in Sudan, can be developed by gaining a thorough understanding of their current status, conservation strategy, and relevant laws and regulations, as well as raising awareness about the importance of protecting endangered species. The Nubian ibex is listed as an endangered species on The International Union for Conservation of Nature (IUCN) Red List, highlighting the need for further research on population conservation efforts due to insufficient population data. To address this knowledge gap, a questionnaire was conducted with various stakeholders, including police officers, researchers, and lecturers, representing a diverse range of organizations and universities. The findings revealed that hunting is the primary factor contributing to endangerment. Mammals account for 80% of endangered species, while reptiles comprise less than one-tenth. Research centers are recognized as the main governing body, and 85% of participants are concerned about the declining population. Hunting accounted for less than half of the threats to the ibex population in Sudan, while habitat loss made up a quarter. Mining, climate change, human activity, and agriculture were also identified as risks. However, there were no plans, strategies, procedures, or measures in place to conserve the Nubian ibex. There were also no initiatives to preserve its biodiversity, and awareness about endangered species was lacking. Although participants believed that laws were effective in protecting the ibex, no licenses were issued for its conservation, and annual surveys were not conducted. Additionally, there were no recorded instances of Mukhalfat related to the Nubian ibex. In light of these findings, we propose various conservation measures to address these challenges. These measures include the implementation of laws and regulations, conducting annual surveys to monitor population trends, protecting habitats, establishing breeding and releasing programs, launching awareness campaigns, undertaking rehabilitation efforts, enhancing research efforts, and developing comprehensive conservation strategies. Additionally, it is crucial to foster cooperation among wildlife institutes to ensure the effective implementation of these conservation measures.

Investigation of 25-Hydroxy Vitamin D Status and Related Factors in Hospitalised Patients with Type 2 Diabetes Mellitus

Objective: To investigate the distribution of 25-hydroxy Vitamin D level status in type 2 diabetes mellitus inpatients, as well as the differences in general conditions and clinical indicators in patients with different Vitamin D status. Methods: Retrospective analysis of 250 admitted type 2 diabetes inpatients admitted to the endocrinology department of qinghai provincial hospital of traditional chinese medicine from september 2022 to december 2023, collated and analysed the general data and laboratory indicators of the patient cases, and applied spss26.0 to process and analyse the data and explore the differences in the general conditions and commonly used clinical nutritional indicators of type 2 diabetes in patients with different 25-hydroxyVitamin D levels. The differences between the different 25-hydroxy Vitamin D levels in type 2 diabetes mellitus patients. Results: 1) A total of 250 inpatients with type 2 diabetes mellitus were included in this study, of which 56 cases (22.4%) were patients with 25 hydroxyvitamin D deficiency [25(OH)D P P P P > 0.05). 3) The distribution of some laboratory indexes among the three groups of patients was differentiated, with the average level of glycated haemoglobin in the lack group being significantly higher than that of the remaining two groups, the average level of albumin being significantly lower than that of the remaining two groups, and the average level of haemoglobin being significantly lower than that of the good group (P P > 0.05). Conclusion: The 25(OH)D level of type 2 diabetes mellitus inpatients is not optimistic. In clinical diagnosis and treatment, we should pay attention to the changes in 25 hydroxyvitamin D levels and other nutritional indexes of patients with type 2 diabetes mellitus, and focus on the control of blood glucose levels and timely supplementation of vitamins, proteins, and lipids, in order to improve the patients’ physical status, reduce the incidence of complications, and improve the clinical efficacy and the patients’ quality of life.

High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and neuroscience.High-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain injury.Several drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system disorders.Although it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system disorders.In this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory role.Research targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

Analyzing the Differences in the Concepts of Love Between Korean and American Women Using the Female Characters in Kim Ji-young,Born in 1982 and The Sun Also Rises as Examples

This paper scrutinizes the differences in the conceptualization of love between Korean and American women.Grounded in an analysis of literary figures,Brett and Kim Ji-young,the study unravels the intricate interplay of cultural,historical,and societal forces shaping these perspectives.The contrasting landscapes of the United States,driven by ideals of freedom and individualism,and Korea,entrenched in Confucian values and collectivism,serve as crucibles for forming women’s roles,self-perception,and societal expectations.The examination extends to communication styles,illuminating the directness of American expression versus Korea’s reliance on formalism.Through this exploration,the paper illustrates the profound impact of cultural contexts on the intricate tapestry of love,offering a nuanced understanding of divergent viewpoints within a global context.

The Existing Problems and Optimization Paths of Digital Textbooks Under Background of Internet

With the rapid development of information technology,the combination of terminal technology,big data and mobile Internet and textbooks has become an irresistible trend in the modern education field.Under the context of the Internet,carrying out education and teaching activities based on digital textbooks can give full play to the rich media,openness and interaction of digital textbooks,broaden students′horizon,enrich students′knowledge,and promote the improvement of students′ability and all-round development.However,in the specific teaching practice,there are also problems such as old compilation ideas,single compilation mode and low efficiency of personalized learning.Therefore,schools and teachers need to constantly innovate the presentation and arrangement of digital textbooks,strengthen technical support,deepen students′understanding of the teaching content of digital textbooks,promote the comprehensive development of students and improve the effectiveness of digital textbook teaching.

Sustainable Intensification and Large-scale Operation of Cultivated Land Use at the Farmers’ Scale:A Case Study of Shandong Province,China

Sustainable intensification of cultivated land use(SICLU) and large-scale operations(LSO) are widely acknowledged strategies for enhancing agricultural performance.However,the existing literature has faced challenges in precisely defining SICLU and constructing comprehensive indicators,which has hindered the exploration of factors influencing LSO within the SICLU framework.To address this gap,we integrated self-efficacy theory into the design of an index framework for evaluating SICLU.We subsequently employed econometric models to analyze the significant factors that impact LSO.Our findings reveal that SICLU can be divided into four key dimensions:intensive management,efficient output,resource conservation,and ecological environment optimization.Furthermore,it is crucial to incorporate belief-based cognitive factors into the index system,as farmers’ understanding of fertilizer and pesticide application significantly influences their willingness to engage in LSO.Moreover,we identify grain market turnover as the most influential factor in promoting LSO,with single-factor contribution rates reaching 70.9% for cultivated land transfer willingness and 62.5% for the total planting areas.Interestingly,unlike irrigation and agricultural machinery inputs,increased labor inputs correspond to larger planting areas for farmers.This trend may be attributed to reduced labor availability because of rural labor migration,whereas the reduction in irrigation and agricultural input is contingent on innovations in production practices and the transfer of cultivated land management rights.Importantly,SICLU dynamically influences LSO,with each index related to SICLU having an optimal range that fosters LSO.These insights offer valuable guidance for policymakers,emphasizing farmers as their central focus,with the adjustment of input and output factors as a means to achieve LSO as the ultimate goal.In conclusion,we propose research avenues for further enriching the SICLU framework to ensure that it aligns with the specific characteristics of regional agricultural development.

Study on The Current Status and Progress of Clinical Application of Ciprofol

Ciprofol,as a new type of short-acting intravenous anesthetic drug,belongs to the category of gamma-aminobutyric acid(GABA)receptor agonists.Its unique chemical structure,through the introduction of the cyclopropyl group in the isopropyl side chain of propofol,constructs a new type of chiral molecule,which significantly enhances the spatial effect,and improves the affinity for GABA receptors.Its pharmacological properties are characterized by high potency,rapid onset of action,rapid recovery,low accumulation,and minimal adverse reactions.Therefore,it has a wide range of applications in various endoscopic diagnostic and therapeutic operations,ICU sedation,and general anesthesia.In this paper,the related knowledge of ciprofol and the development of clinical application research are comprehensively sorted out and synthesized,to provide a solid theoretical basis for the rational application of ciprofol in clinical practice.At the same time,the future research direction of ciprofol will also be prospected to provide valuable references for research in related fields.

Floristic Diversity and Conservation Status of Guineo-Congolese Species in Southeastern Cameroon: The Case of the Gari-Gombo Communal Forest

The conservation of plant biodiversity has become one of the most important objectives in the sustainable management of Guinean-Congolese ecosystems. However, in the south-east zone of Cameroon, there is a lack of rigor in the management of these forests, which can result in the loss of species of high conservation value. The study was carried out in communal forests in the south-east zone of Cameroon. Its aim was to carry out a floristic inventory and then compare the list of species with the IUCN catalog. Twenty-four plots, each with a surface area of 0.2 ha, were set up in the Gari-Gombo communal forest. All timbers with a DBH ≥ 5 cm were systematically counted. A total of 176 species, belonging to 144 genera and 45 families, were surveyed. Fabaceae (42.08%), Malvaceae (39%), Euphorbiaceae (24.64%), Moraceae (20.92%), Apocynaceae (18.64%), Cecropiaceae (16.60%), Ulmaceae (14.76%), Meliaceae (14.61%), Violaceae (14.08%), Combretaceae (12.67%), Theobroma cacao (21.17%), Baphia leptobotrys (18.06%), Rinorea sp. (14.09%), Musanga cecropioides (12.18%), Terminalia superba (10.32%), Neosloetiopsis kamerunensis (10.14%), Celtis zenkeri (8.29%) and Alstonia boonei (7.77%) were the most important taxa. Nearly 90% of the species in this forest are Guinean species, with a dominance of Guinean-Congolese species (66%). Fourteen (14) threatened species have been identified in the FCGG. This study, which highlights the rich biodiversity of communal forests, is important for guiding biodiversity conservation policies in ecosystems used for production.

Hungry and Angry Society: Implications for Sustainable Development in Nigeria

Hunger is a physiological need,but the production and consumption of adequate and balanced food is a function of social forces.At every point,social,political,and economic processes intervene,for better or(more common)for worse.Food is one fundamental need of human beings for survival.But in Nigeria there is widespread food shortage and hunger.Development scholars have put forward reasons why poverty,hunger persists in the country,from the platitudes about population growth,inadequate implementation of agricultural policies,and neglect of agriculture,bad leadership,corruption,and the issue of distribution.Nigeria is richly blessed with arable land and citizens eager to unlock its food potentials.Unfortunately,this is far from being realized as the country depends on foreign countries for food,a situation that is tragic and sad.She spends about$10 billion a year importing food and agricultural products,the majority of which are wheat,rice,poultry,fish,and consumer-oriented foods.The pressure on the exchange rate results in devaluation-triggered inflation and food costs that fly up beyond the grasp of people at the bottom of the ladder as it is now is one of the negative repercussions of high food importation bills.Examining the effects of hunger is one of this paper’s key concerns and goals,and anger crisis for achieving sustainable development in the country using the Frustration-Aggression Theory,The Relative Deprivation and Political Economy Approach as guide.

Effect of Early Enteral Nutrition Combined with Probiotics on the Nutritional Status of Patients with Severe Craniocerebral Injury

Objective:To observe the effect of early enteral nutrition combined with probiotics on the nutritional status of patients with severe craniocerebral injury.Methods:Thirty-five patients with severe craniocerebral injury were divided into the study group(17 patients)and the control group(18 patients)according to the method of a randomized numerical table;both groups of patients started enteral nutrition via nasogastric tube within 24–48 hours after admission to the hospital,and probiotics were given in addition to the study group.Hemoglobin,total plasma protein,albumin,prealbumin,cholinesterase,fasting blood glucose,and other indexes were monitored before and early morning after enteral nutrition support,and upper arm circumference(AC),triceps skinfold thickness(TSF),and upper arm muscle circumference(AMC)were measured,and gastrointestinal response and time to first defecation of the patients were observed and compared with GCS score.Results:The hemoglobin,serum albumin,prealbumin,cholinesterase,and total plasma protein levels in the study group were significantly higher and fasting blood glucose levels were significantly lower than those in the control group after treatment(P<0.05).The incidence of reflux and constipation in the study group was lower than that in the control group,and the time to first defecation was shorter than that in the control group(P<0.05).After treatment,AC,TSF,and AMC were higher in the study group than in the control group(P<0.05).GCS scores were significantly higher in both groups after treatment,but the trend was more pronounced in the study group(P<0.05).Conclusion:Compared with simple enteral nutrition,enteral nutrition combined with probiotics can better correct metabolic disorders after heavy craniocerebral injury and improve the nutritional status of patients.