The endoplasmic reticulum(ER)is connected to mitochondria through mitochondria-associated ER membranes(MAMs).MAMs provide a framework for crosstalk between the ER and mitochondria,playing a crucial role in regulating ...The endoplasmic reticulum(ER)is connected to mitochondria through mitochondria-associated ER membranes(MAMs).MAMs provide a framework for crosstalk between the ER and mitochondria,playing a crucial role in regulating cellular calcium balance,lipid metabolism,and cell death.Dysregulation of MAMs is involved in the development of chronic liver disease(CLD).In CLD,changes in MAMs structure and function occur due to factors such as cellular stress,inflammation,and oxidative stress,leading to abnormal interactions between mitochondria and the ER,resulting in liver cell injury,fibrosis,and impaired liver function.Traditional Chinese medicine has shown some research progress in regulating MAMs signaling and treating CLD.This paper reviews the literature on the association between mitochondria and the ER,as well as the intervention of traditional Chinese medicine in regulating CLD.展开更多
On Sept.27, 2005, China Certification and Accreditation Association was set up, which was a sign of standardization and legalization for China certification and accreditation. Furthermore, its main task includes suppo...On Sept.27, 2005, China Certification and Accreditation Association was set up, which was a sign of standardization and legalization for China certification and accreditation. Furthermore, its main task includes supporting fairness, gaining credit, promoting development and building a harmonious society.展开更多
The emerging development of Extractive Reference Substance (ERS) is a methodology that meets the needs for quality control for Chinese Herbal Medicines (CHM) and respects the holistic viewpoint of Traditional Chinese ...The emerging development of Extractive Reference Substance (ERS) is a methodology that meets the needs for quality control for Chinese Herbal Medicines (CHM) and respects the holistic viewpoint of Traditional Chinese Medicine (TCM) and its clinical use of multiple ingredients with synergistic effects. The convention of using just a selected few Chemical Reference Substances (CRS) cannot adequately assess the quality of intact CHM. A validated chemical spectrum of an ERS provides the global characteristics in order to more specifically identify and assess targeted CHM. This paper describes the fundamental concepts, potential significance, and basic criteria of ERS, along with methods of preparation and calibration. Given the diversity of CHM, the various problems that will occur in establishing the proper process of ERS will need to be solved in a step by step manner. The ERSs of Ziziphi spinosae semen and ERS of Fritillaria thunbergii bulbus are given as examples of the development of ERS and demonstrate why we are optimistic about the utility of this approach.展开更多
翻译偏离通常源于语言的文化差异、译者的识解能力和方式的局限。兰盖克(Langacker)2019年最新提出的识解理论五维度,为认识The Sound and the Fury四个汉译本中的认知偏离现象提供了理论支撑。这些汉译本中的偏离现象虽遵循认知规律,...翻译偏离通常源于语言的文化差异、译者的识解能力和方式的局限。兰盖克(Langacker)2019年最新提出的识解理论五维度,为认识The Sound and the Fury四个汉译本中的认知偏离现象提供了理论支撑。这些汉译本中的偏离现象虽遵循认知规律,但深层原因主要涉及译者的视角差异、场景选择、信息突显、动态性表达及想象性再现等多个层面。在语言认知加工过程中,译者的认知框架和识解方式,以及他们与源语文本、作者和读者之间的认知互动对意义的动态构建会产生显著的影响和制约。展开更多
Chinese radioglaciological studies on the Antarctic ice sheet(AIS) began in 2004/05 when the 21 st Chinese National Antarctic Research Expedition(CHINARE 21) team arrived at Dome A for the first time and radio echo so...Chinese radioglaciological studies on the Antarctic ice sheet(AIS) began in 2004/05 when the 21 st Chinese National Antarctic Research Expedition(CHINARE 21) team arrived at Dome A for the first time and radio echo sounding(RES) was conducted along the inland traverse and in the Dome A region. Subsequently, more field surveys were conducted along the traverse and in the Dome A region using different radar systems targeting different scientific purposes, such as revealing the landscape of the Gamburtsev Subglacial Mountains by detailed grid RES, or locating a deep ice core drilling site by mapping and studying internal structures, bedrock topography and subglacial conditions in the Dome A region. Furthermore, the evolution of the AIS was inferred from the typical mountain glaciation topography beneath Dome A, and the age of the deep ice core at Kunlun Station was estimated through numerical modeling. Recently, the Snow Eagle 601 airplane was acquired and an airborne geophysical system was constructed to survey the AIS in Princess Elizabeth Land during CHINARE 32(2015/16) and CHINARE 33(2016/17) in order to fill the large data gap there. In this paper, we review both the recent progress of Chinese radioglaciological science in Antarctica and future proposed work.展开更多
基金Supported by the National Natural Science Foundation of China,No.82204755,and No.81960751the Guangxi Natural Science Foundation Youth Project,No.2023GXNSFBA026274+1 种基金the Guangxi University of Traditional Chinese Medicine School-level Project Youth Fund,No.2022QN008Faculty of Chinese Medicine Science Guangxi University of Chinese Medicine Research Project,No.2022MS008 and No.2022QJ001.
文摘The endoplasmic reticulum(ER)is connected to mitochondria through mitochondria-associated ER membranes(MAMs).MAMs provide a framework for crosstalk between the ER and mitochondria,playing a crucial role in regulating cellular calcium balance,lipid metabolism,and cell death.Dysregulation of MAMs is involved in the development of chronic liver disease(CLD).In CLD,changes in MAMs structure and function occur due to factors such as cellular stress,inflammation,and oxidative stress,leading to abnormal interactions between mitochondria and the ER,resulting in liver cell injury,fibrosis,and impaired liver function.Traditional Chinese medicine has shown some research progress in regulating MAMs signaling and treating CLD.This paper reviews the literature on the association between mitochondria and the ER,as well as the intervention of traditional Chinese medicine in regulating CLD.
文摘On Sept.27, 2005, China Certification and Accreditation Association was set up, which was a sign of standardization and legalization for China certification and accreditation. Furthermore, its main task includes supporting fairness, gaining credit, promoting development and building a harmonious society.
文摘The emerging development of Extractive Reference Substance (ERS) is a methodology that meets the needs for quality control for Chinese Herbal Medicines (CHM) and respects the holistic viewpoint of Traditional Chinese Medicine (TCM) and its clinical use of multiple ingredients with synergistic effects. The convention of using just a selected few Chemical Reference Substances (CRS) cannot adequately assess the quality of intact CHM. A validated chemical spectrum of an ERS provides the global characteristics in order to more specifically identify and assess targeted CHM. This paper describes the fundamental concepts, potential significance, and basic criteria of ERS, along with methods of preparation and calibration. Given the diversity of CHM, the various problems that will occur in establishing the proper process of ERS will need to be solved in a step by step manner. The ERSs of Ziziphi spinosae semen and ERS of Fritillaria thunbergii bulbus are given as examples of the development of ERS and demonstrate why we are optimistic about the utility of this approach.
文摘翻译偏离通常源于语言的文化差异、译者的识解能力和方式的局限。兰盖克(Langacker)2019年最新提出的识解理论五维度,为认识The Sound and the Fury四个汉译本中的认知偏离现象提供了理论支撑。这些汉译本中的偏离现象虽遵循认知规律,但深层原因主要涉及译者的视角差异、场景选择、信息突显、动态性表达及想象性再现等多个层面。在语言认知加工过程中,译者的认知框架和识解方式,以及他们与源语文本、作者和读者之间的认知互动对意义的动态构建会产生显著的影响和制约。
基金financially supported by the National Natural Science Foundation of China (Grant nos. 41776186, 41730102 and 41571407)the Chinese Polar Environmental Comprehensive Investigation and Assessment Programs (Grant no. CHINARE-02-02)
文摘Chinese radioglaciological studies on the Antarctic ice sheet(AIS) began in 2004/05 when the 21 st Chinese National Antarctic Research Expedition(CHINARE 21) team arrived at Dome A for the first time and radio echo sounding(RES) was conducted along the inland traverse and in the Dome A region. Subsequently, more field surveys were conducted along the traverse and in the Dome A region using different radar systems targeting different scientific purposes, such as revealing the landscape of the Gamburtsev Subglacial Mountains by detailed grid RES, or locating a deep ice core drilling site by mapping and studying internal structures, bedrock topography and subglacial conditions in the Dome A region. Furthermore, the evolution of the AIS was inferred from the typical mountain glaciation topography beneath Dome A, and the age of the deep ice core at Kunlun Station was estimated through numerical modeling. Recently, the Snow Eagle 601 airplane was acquired and an airborne geophysical system was constructed to survey the AIS in Princess Elizabeth Land during CHINARE 32(2015/16) and CHINARE 33(2016/17) in order to fill the large data gap there. In this paper, we review both the recent progress of Chinese radioglaciological science in Antarctica and future proposed work.
