In the context of deepening educational reforms,the significance of ideological and political education has become increasingly prominent,emerging as a crucial aspect of enhancing students’comprehensive qualities.To ...In the context of deepening educational reforms,the significance of ideological and political education has become increasingly prominent,emerging as a crucial aspect of enhancing students’comprehensive qualities.To ensure the orderly progress of ideological and political education in courses,it is essential to actively promote the integration of ideological and political elements within coursework.This integration aims to align professional course education with ideological and political education,fostering a collaborative educational model.Therefore,in the teaching of bidding and contract management courses,constructing a“micro-ideological and political”teaching model has emerged as a critical component.The implementation of this model facilitates the seamless integration of bidding and contract management coursework with ideological and political education,thereby elevating the teaching quality of these courses.Additionally,it leverages the synergistic role of coursework and ideology in educating students,ultimately enhancing the quality and level of talent cultivation.Hence,this paper proposes strategies for constructing a“microideological and political”model within the context of ideological and political teaching reforms in bidding and contract management courses,inviting discussion and exchange on this topic.展开更多
[ Objective] The aim of this experiment was to explore the effects of different rearing modes on muscle histological traits and muscle ten demess and to provide theoretical basis for regulating chicken meat quality. [...[ Objective] The aim of this experiment was to explore the effects of different rearing modes on muscle histological traits and muscle ten demess and to provide theoretical basis for regulating chicken meat quality. [ Method] The effects of outdoor rearing, indoor rearing and cage rea ring modes on the muscular histological traits and meat tenderness of Hetian chicken at the age of 8 weeks, 12 weeks and 16 weeks were re searched. [Result] The results showed that the breast and thigh muscle fibre diameter and muscle shear force of outdoor rearing chicken were sig nificently higher than that of cage rearing chicken ( P 〈 0.05), and muscle fibre density was significantly lower than that of cage rearing chicken ( P 〈 0.05). With aging, the muscle fibre diameter and shear force increased and muscle fibre density decreased ( P 〈 0.05). The muscle fibre di ameter and shear force of male were higher than that of female. The correlation analysis showed that the breast muscle shear force had a signifi cantly positive relation with fibre diameter and negative relation with fibre density ( P 〈 0.05), but thigh muscle shear force had an insignificantly pos itive relation with fibre diameter and fibre density. [ Condusion] Muscular histological traits varied in different rearing modes, and the outdoor rearing promoted the muscular fibre development and increased the muscular shear force.展开更多
The possibility and rationality of introducing an bid-winning estimate based on a reasonable low price into construction bidding mode with bill of quantities were analyzed by setting up a model for bidding and tenderi...The possibility and rationality of introducing an bid-winning estimate based on a reasonable low price into construction bidding mode with bill of quantities were analyzed by setting up a model for bidding and tendering, and the functions of the estimate of reasonable low price in the bidding were revealed. On this basis, a new bidding mode of the project with bill of quantities was pro- posed. The application of the new mode will be advantageous to the promotion of the bill of quantities in China.展开更多
This work suggested a novel model for obtaining optimum bidding/offering strategy to improve the benefits in case of big users.Aiming this regard,several electrical energy resources including:micro turbines,green powe...This work suggested a novel model for obtaining optimum bidding/offering strategy to improve the benefits in case of big users.Aiming this regard,several electrical energy resources including:micro turbines,green power sources(wind turbine and photovoltaic system),power storage unit such as Hydrogen storage system with fuel cell,as well as mutual treaties are taken into account in offered model.Considering various models for uncertain parameters based on their natures such as power demand,electricity market tariffs,solar irradiation,temperature and wind speed is one of the contributions of the proposed model.Uncertainty of power demand is modeled by robust optimal method whereas remain uncertain parameters are incorporated in model by stochastic method.Considering of wind speed cased is made by Weibull distribution.While,normal distribution is utilized for production of cases for electricity market tariffs,solar irradiation and temperature.In order to reduce the bidding error loss,the storage devices are corporate with green energy in power unbalanced conditions.Combined-integer linear programming method is applied for handling of pricing method profiles that have strength against considered uncertainties on power demand of big user.The obtained results confirm,the entire electrical energy supplement expenditure of big user in absence of demand uncertainty is$39.63 whereas it is augmented up to$49.47 to achieve robustness vs.demand uncertainty.Also,using of hydrogen storage system by considering the reliability index is reduced the bidding price of the system.展开更多
Electrocatalysis is key to improving energy efficiency,reducing carbon emissions,and providing a sustainable way of meeting global energy needs.Therefore,elucidating electrochemical reaction mechanisms at the electrol...Electrocatalysis is key to improving energy efficiency,reducing carbon emissions,and providing a sustainable way of meeting global energy needs.Therefore,elucidating electrochemical reaction mechanisms at the electrolyte/electrode interfaces is essential for developing advanced renewable energy technologies.However,the direct probing of real-time interfacial changes,i.e.,the surface intermediates,chemical environment,and electronic structure,under operating conditions is challenging and necessitates the use of in situ methods.Herein,we present a new lab-based instrument commissioned to perform in situ chemical analysis at liquid/solid interfaces using ambient pressure X-ray photoelectron spectroscopy(APXPS).This setup takes advantage of a chromium source of tender X-rays and is designed to study liquid/solid interfaces by the“dip and pull”method.Each of the main components was carefully described,and the results of performance tests are presented.Using a three-electrode setup,the system can probe the intermediate species and potential shifts across the liquid electrolyte/solid electrode interface.In addition,we demonstrate how this system allows the study of interfacial changes at gas/solid interfaces using a case study:a sodium–oxygen model battery.However,the use of APXPS in electrochemical studies is still in the early stages,so we summarize the current challenges and some developmental frontiers.Despite the challenges,we expect that joint efforts to improve instruments and the electrochemical setup will enable us to obtain a better understanding of the composition–reactivity relationship at electrochemical interfaces under realistic reaction conditions.展开更多
In Bangladesh, both manual and e-GP system is used to perform public procurement. Before tender publication, tender documents have to be prepared by the Procurement Entities (PEs). The problem is that the manual tende...In Bangladesh, both manual and e-GP system is used to perform public procurement. Before tender publication, tender documents have to be prepared by the Procurement Entities (PEs). The problem is that the manual tendering system involves more cost and time in preparing tender documents. The study’s purpose is to compare now the efficiency of tender document preparation in the manual system with the e-GP system. This study tests the cost and time involved in tender document preparation, both manual and e-procurement tenders. Sample data was collected from the 11 RHD zones. Structured survey questionnaires were used to collect primary data from the PE officers of RHD. A hypothesis test was performed using the model of independent samples t-test. The test results indicated that e-Procurement tender document preparation costs and time were less than manual tendering. Academicians, researchers, PE officers, and policymakers will benefit from the study’s conclusions.展开更多
This paper discusses aspects related to competitiveness in the ITB (invitation to bid) of the public tender for the concession of the urban bus public transport services in the RMR (Metropolitan Region of Recife) ...This paper discusses aspects related to competitiveness in the ITB (invitation to bid) of the public tender for the concession of the urban bus public transport services in the RMR (Metropolitan Region of Recife) in the Brazilian northeastern region. The bid was made public through a consortium formed by the two major cities of the RMR--Recife and Olinda, and the government of the State of Pernambuco. Throughout the paper, the basic features of the bidding terms are presented and some aspects of these characteristics that undermine competitiveness are pointed out and submitted to criticisms. Aspects such as the small number of lots, the lack of diversification of lot sizes and the possibility of forming consortia with unlimited number of participants were targeted. In order to prove the criticisms stated, a simulation of an arrangement amongst incumbents is presented, based on the rules of the tender, in which the allocation of incumbents ex post bidding does not differ from the ex ante scenario. Thus, the main objective of this article is to assess whether good practices that foster competition were followed by the ITB and the main conclusion is that competitiveness was put in jeopardy.展开更多
Bangladesh’s public procurement system has been traditional, i.e., a manual tendering system, under the legislative guidance of PPA-2006 and PPR-2008. Manual tendering has long been a source of concern for public pro...Bangladesh’s public procurement system has been traditional, i.e., a manual tendering system, under the legislative guidance of PPA-2006 and PPR-2008. Manual tendering has long been a source of concern for public procurement agencies regarding tender opening related to cost and time. To resolve this challenge and make the dream of a Digital Bangladesh a reality, the Government of Bangladesh launched the e-Procurement system in 2011 under the flagship of e-GP Guidelines. Following the successful pilot testing conducted under the umbrella of the CPTU, all public PEs are attempting to implement electronic procurement tenders. This study aims to examine the cost and time involved in preparing Tender Opening Committee (TOC) Reports for manual and e-procurement tenders in Bangladesh’s Roads and Highways Department. A mixed-method was used to collect data from the population of 11 RHD zones, including KII and primarily survey questionnaires. The independent samples t-test was used to compare data and hypothesis tests from two groups using SPSS software. The results indicated that e-Procurement tendering, tender opening preparation costs and time were more efficient than manual tendering. Academicians, students, practitioners, researchers, and policymakers will benefit from the study’s conclusions. Additionally, the government will be urged to improve policies such as the PPA 2006, the PPR 2008, and the 2011 e-GP Guideline.展开更多
Bidding is a key link during the implementation of a construction project.For the same construction project,there are usually multiple construction companies bidding together to obtain the right to contract for the pr...Bidding is a key link during the implementation of a construction project.For the same construction project,there are usually multiple construction companies bidding together to obtain the right to contract for the project.However,there are still various irregularities in the bidding stage.This article analyzed the above problems and proposed a management strategy for the optimization of bidding,looking forward to improving the quality of bidding management of construction projects,solving various illegal bidding problems,and purifying the environment of bidding management.展开更多
Objective' To study the muscular histological traits and their relationship with meat tenderness in local broilers and provide a theoretical basis for promoting meat quality of broiler. [Methed] The diameter and dens...Objective' To study the muscular histological traits and their relationship with meat tenderness in local broilers and provide a theoretical basis for promoting meat quality of broiler. [Methed] The diameter and density of muscle fiber of three local varieties of chicken (Beijing Fatty broil- er, Fujian Hetian broiler and Taining Black broiler) were detected at the age of 8 weeks, 12 weeks and 16 weeks. And the differences in the diame- ter and density of muscle fiber as well as their relationship with meat tenderness were respectively analyzed with SAS software. [ Resultl Fatty broil- er had the smallest muscle fiber diameter while Hetian broiler the largest; Fatty broiler had the highest muscle fiber density while Hetian broiler the lowest Hetian broiler had the highest muscle shear force of leg muscle while Black broiler the lowest ( P 〈0.05) ; Black broiler had the highest mus- cle shear force of breast muscle while Fatty broiler the lowest (P〈0.05). The correlation analysis showed that the shear force of breast muscle and leg muscle had significantly positive relation with fiber diameter and significantly negative relation with fiber density ( P 〈 0.05). [ Conclusion] Muscu- lar histological traits varied in different local broilers, and the muscular shear force had significantly relation with fiber diameter and density.展开更多
[Objective] The study was carried out in order to find out the best method of rapid cutting rooting of Syriga microphylla with tender branches.[Method] Effect of rooting reagent with different concentrations on the ra...[Objective] The study was carried out in order to find out the best method of rapid cutting rooting of Syriga microphylla with tender branches.[Method] Effect of rooting reagent with different concentrations on the rapid cutting rooting of Syriga microphylla with tender branches was studied in our paper.[Result] There was great difference between cuttings with auxin and without auxin.[Conclusion] Tender branches treated by 90 mg/L indole butyric acid(IBA)had the best cutting rooting.展开更多
Two major apoptosis pathways have been defined in mammalian cells, the Fas/TNF-R1 death receptor pathway and the mitochondria pathway. The Bcl-2 family proteins consist of both anti-apoptosis and pro- apoptosis member...Two major apoptosis pathways have been defined in mammalian cells, the Fas/TNF-R1 death receptor pathway and the mitochondria pathway. The Bcl-2 family proteins consist of both anti-apoptosis and pro- apoptosis members that regulate apoptosis, mainly by controlling the release of cytochrome c and other mitochondrial apoptotic events. However, death signals mediated by Fas/TNF-R1 receptors can usually activate caspases directly, bypassing the need for mitochondria and escaping the regulation by Bcl-2 family proteins. Bid is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Activated Bid is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Such a connection between the two apoptosis pathways could be important for induction of apoptosis in certain types of cells and responsible for the pathogenesis of a number of human diseases.展开更多
Objective:To investigate whether tender coconut water(TCW) mitigates oxidative stress in fructose fed hypertensive rats.Methods:Male Sprague Dawley rats were fed with fructose rich diet and treated with TCW(4 mL/100 g...Objective:To investigate whether tender coconut water(TCW) mitigates oxidative stress in fructose fed hypertensive rats.Methods:Male Sprague Dawley rats were fed with fructose rich diet and treated with TCW(4 mL/100 g of body weight) for 3 subsequent weeks.Systolic blootl pressure was measured every three days using the indirect tail cuff method.At the end of the experimental period,plasma glucose and insulin,serum triglycerides and free fatly acids, lipid peroxidation markers(MDA,hydroperoxides and conjugated dienes) and the activities of antioxidant enzymes were analyzed in all the groups.Results:Treatment with TCW significandy lowered the systolic blood pressure and reduced serum triglycerides and free fatty acids.Plasma glucose and insulin levels and lipid peroxidation markers such as MDA,hydroperoxides and conjugated dienes were significantly reduced in fructose fed rats treated with TCW.Activities of antioxidant enzymes are up regulated significantly in TCW treated rats.Hislopathological analysis of liver showed that TCW treatment reduced the lipid accumulation and inflammatory infiltration without any significant hepatocellular damage.Conclusions:The overall results suggest that, TCW treatment could prevent and reverse high blood pressure induced by high fructose diet probably by inhibition of lipid peroxidation,upregulation of antioxidant status and improved insulin sensitivity.展开更多
Aging is a popular method used by meat industry for improving the sensory attributes of meat.Despite the advent of many novel technologies,aging has not lost its charm and is still widely used commercially as a post-m...Aging is a popular method used by meat industry for improving the sensory attributes of meat.Despite the advent of many novel technologies,aging has not lost its charm and is still widely used commercially as a post-mortem intervention for tenderization.Aging improves the tenderness of meat through disruption of the muscle structure by intracellular proteolytic systems.Muscles undergo various molecular changes that cause proteolysis of key myofibrillar and cytoskeletal proteins,disrupting the overall integrity of muscle cells.Although several endogenous proteolytic systems are capable of post-mortem proteolysis,a great body of scientific evidence supports a major role for the calpain system.Calpains are intracellular calcium-dependent cysteine proteases found in most eukaryotes.At least three calpains(μ-and m-calpains and calpain 3)and calpastatin,their specific endogenous inhibitor,are found in muscle.They are known to be involved in the proteolysis of functionally relevant structural proteins such as the myofibrillar proteins and cytoskeletal anchorage complexes.These ubiquitous proteases are also present in mitochondria and play important roles in a variety of pathophysiological conditions including apoptotic and necrotic cell death phenomena.This review discusses the role and contribution of the calpain system and the factors that influence calpain activity during aging.展开更多
The development of deepwater oil fields has reached a new stage with the dramatic increase in water depth and the recent increasing demands of the economic development in the filed. The use of a Tension Leg Platform ...The development of deepwater oil fields has reached a new stage with the dramatic increase in water depth and the recent increasing demands of the economic development in the filed. The use of a Tension Leg Platform (TIP) combined with other systems, such as Floating Production Storage and Offloading (FPSO) system, Floating Production Unit (FPU) system, Tender Assisted Drilling (TAD) system, etc., has drawn the industry attention and increased significantly in the past few years. For the areas lacking of pipeline system, the use of TIP(s) combined with FPSO has been chosen to efficiently develop the deepwater fields. The TIP with a Tender Assisted Drilling system significantly reduces the payload of the platform and reduces the investment in the TIP system substantially. This opens the door for many new deepwater field developments to use the tension leg platform. The advantage of the TIP combined with a TAD system is more significant when several TIPs are used for the continuous development of the field. One of the applications for the TIP with a tender assisted drilling system can be in the development of an offshore marginal field. Owing to the increase of water depth, the conventional fixed platform model for the exploration of those fields becomes uneconomical. It also would be too expensive to use a large TIP structure for those marginal fields due to the large amount of initial investment. The TIP system with tender assisted drilling can be used to develop those fields economically. There are many marginal fields in China offshore, especially in shelf areas. The application of this field developing model, combined with the existing field developing experience in China, will open the door for many marginal field developments. This paper will review the application of the combined TIP system through some examples of completed/ongoing projects, and major technical issues encountered in those practices. The potential application of this technology in China deepwater development will be discussed in the end.展开更多
The aim of this study was to determine the effects of age on chemical composition and tenderness of donkey meat. These characteristics were determined on Longissimus thoracis samples taken from 40 entire donkey males ...The aim of this study was to determine the effects of age on chemical composition and tenderness of donkey meat. These characteristics were determined on Longissimus thoracis samples taken from 40 entire donkey males of Martina Franca breed slaughtered at 12 (Group 1, n = 20) and at 18 months (Group 2, n = 20) of age. Tenderness was evalu-ated at two and seven days post slaughter using a Warner-Bratzler shear force device. The chemical composition showed a significant increase in protein content (P < 0.05) in the meat of donkeys slaughtered at 18 months of age (22.3 g/100 g) compared to the meat of younger animals (21.4 g/100 g). Intramuscular fat content was significantly lower (P < 0.05) in Group 1 (2.41 g/100 g) compared to Group 2 (3.71 g/100 g). Shear force values at seven days post slaughter were significantly (P < 0.01) lower (5.15 ± 0.31 kg/cm2) in Group 1 compared with the results obtained at two days post slaughter (6.25 ± 0.53 kg/cm2). In Group 2 shear force values obtained seven days post mortem were higher (5.88 ± 0.23 kg/cm2) compared with Group 1 after the same ageing period but significantly (P < 0.05) lower if compared with those (6.53 ± 0.23 kg/cm2) determined in the same animals two days post slaugher.展开更多
In this study,endoplasmic reticulum(ER)stress inducer tunicamycin(TM)and inhibitor 4-phenylbutyric acid(4-PBA)were used to treat postmortem chicken breast muscle to investigate changes in tenderness and effects on apo...In this study,endoplasmic reticulum(ER)stress inducer tunicamycin(TM)and inhibitor 4-phenylbutyric acid(4-PBA)were used to treat postmortem chicken breast muscle to investigate changes in tenderness and effects on apoptosis and autophagy during 5 days ageing.TM-induced ER stress reduced shear force,enhanced myofibril fragmentation index(MFI),disrupted myofibril structure,increased desmin degradation,and activatedμ-calpain and caspase-12.In addition,TM-induced ER stress increased the expression of Bax,Bim,and cytochrome c,and decreased the expression of Bcl-x L.Furthermore,TM-induced ER stress improved the conversion of LC3I to LC3II,raised the expression of Beclin-1,and decreased the expression of p62,PI3K,and m TOR.The opposite results were observed after 4-PBA treatment.These results suggested that ER stress could improve chicken tenderness,promote apoptosis and autophagy during chicken postmortem ageing.展开更多
This paper puts forward a new framework of multi-agent based equipment bidding system on the Web (MAEBSW). The purpose of the paper is to make the process of enterprise equipment bidding, especially the decision proce...This paper puts forward a new framework of multi-agent based equipment bidding system on the Web (MAEBSW). The purpose of the paper is to make the process of enterprise equipment bidding, especially the decision process of enterprise equipment bidding, more intelligent. The system discussed in this paper is an efficient method for the enterprises doing business electronically. We also present our opinion of the approaches to defining agents. We emphasize the importance of agent being able to provide explanation about its behavior for the user or other agents. Based on this opinion we design a new common architecture of most agents in MAEBSW.展开更多
The calpain system is ubiquitous in cells, mainly comprising calpains and calpain inhibitors, and is a widespread calcium-dependent cysteine protease in organisms that is involved in many cellular processes such as mu...The calpain system is ubiquitous in cells, mainly comprising calpains and calpain inhibitors, and is a widespread calcium-dependent cysteine protease in organisms that is involved in many cellular processes such as muscle degradation in vivo and affects the tenderness of meat after animal slaughter. The study found 128 DEGs that probably regulated tenderness traits were selected from 16 significantly enriched GO terms by transcriptome sequencing analysis, and found that the developmental changes in the expression levels of the CAPN1 gene in the pectoral and leg muscles were significantly positively correlated ( P <0.05) with the cumulative growth values of live weight and comb weight. The developmental changes in the expression levels of the CAST gene in the pectoral and leg muscles were not significantly correlated with the cumulative growth values of live weight and comb weight. Our results helped demonstrate the potential molecular mechanisms of tenderness in chickens and provide valuable information for chicken breeding.展开更多
文摘In the context of deepening educational reforms,the significance of ideological and political education has become increasingly prominent,emerging as a crucial aspect of enhancing students’comprehensive qualities.To ensure the orderly progress of ideological and political education in courses,it is essential to actively promote the integration of ideological and political elements within coursework.This integration aims to align professional course education with ideological and political education,fostering a collaborative educational model.Therefore,in the teaching of bidding and contract management courses,constructing a“micro-ideological and political”teaching model has emerged as a critical component.The implementation of this model facilitates the seamless integration of bidding and contract management coursework with ideological and political education,thereby elevating the teaching quality of these courses.Additionally,it leverages the synergistic role of coursework and ideology in educating students,ultimately enhancing the quality and level of talent cultivation.Hence,this paper proposes strategies for constructing a“microideological and political”model within the context of ideological and political teaching reforms in bidding and contract management courses,inviting discussion and exchange on this topic.
文摘[ Objective] The aim of this experiment was to explore the effects of different rearing modes on muscle histological traits and muscle ten demess and to provide theoretical basis for regulating chicken meat quality. [ Method] The effects of outdoor rearing, indoor rearing and cage rea ring modes on the muscular histological traits and meat tenderness of Hetian chicken at the age of 8 weeks, 12 weeks and 16 weeks were re searched. [Result] The results showed that the breast and thigh muscle fibre diameter and muscle shear force of outdoor rearing chicken were sig nificently higher than that of cage rearing chicken ( P 〈 0.05), and muscle fibre density was significantly lower than that of cage rearing chicken ( P 〈 0.05). With aging, the muscle fibre diameter and shear force increased and muscle fibre density decreased ( P 〈 0.05). The muscle fibre di ameter and shear force of male were higher than that of female. The correlation analysis showed that the breast muscle shear force had a signifi cantly positive relation with fibre diameter and negative relation with fibre density ( P 〈 0.05), but thigh muscle shear force had an insignificantly pos itive relation with fibre diameter and fibre density. [ Condusion] Muscular histological traits varied in different rearing modes, and the outdoor rearing promoted the muscular fibre development and increased the muscular shear force.
文摘The possibility and rationality of introducing an bid-winning estimate based on a reasonable low price into construction bidding mode with bill of quantities were analyzed by setting up a model for bidding and tendering, and the functions of the estimate of reasonable low price in the bidding were revealed. On this basis, a new bidding mode of the project with bill of quantities was pro- posed. The application of the new mode will be advantageous to the promotion of the bill of quantities in China.
文摘This work suggested a novel model for obtaining optimum bidding/offering strategy to improve the benefits in case of big users.Aiming this regard,several electrical energy resources including:micro turbines,green power sources(wind turbine and photovoltaic system),power storage unit such as Hydrogen storage system with fuel cell,as well as mutual treaties are taken into account in offered model.Considering various models for uncertain parameters based on their natures such as power demand,electricity market tariffs,solar irradiation,temperature and wind speed is one of the contributions of the proposed model.Uncertainty of power demand is modeled by robust optimal method whereas remain uncertain parameters are incorporated in model by stochastic method.Considering of wind speed cased is made by Weibull distribution.While,normal distribution is utilized for production of cases for electricity market tariffs,solar irradiation and temperature.In order to reduce the bidding error loss,the storage devices are corporate with green energy in power unbalanced conditions.Combined-integer linear programming method is applied for handling of pricing method profiles that have strength against considered uncertainties on power demand of big user.The obtained results confirm,the entire electrical energy supplement expenditure of big user in absence of demand uncertainty is$39.63 whereas it is augmented up to$49.47 to achieve robustness vs.demand uncertainty.Also,using of hydrogen storage system by considering the reliability index is reduced the bidding price of the system.
文摘Electrocatalysis is key to improving energy efficiency,reducing carbon emissions,and providing a sustainable way of meeting global energy needs.Therefore,elucidating electrochemical reaction mechanisms at the electrolyte/electrode interfaces is essential for developing advanced renewable energy technologies.However,the direct probing of real-time interfacial changes,i.e.,the surface intermediates,chemical environment,and electronic structure,under operating conditions is challenging and necessitates the use of in situ methods.Herein,we present a new lab-based instrument commissioned to perform in situ chemical analysis at liquid/solid interfaces using ambient pressure X-ray photoelectron spectroscopy(APXPS).This setup takes advantage of a chromium source of tender X-rays and is designed to study liquid/solid interfaces by the“dip and pull”method.Each of the main components was carefully described,and the results of performance tests are presented.Using a three-electrode setup,the system can probe the intermediate species and potential shifts across the liquid electrolyte/solid electrode interface.In addition,we demonstrate how this system allows the study of interfacial changes at gas/solid interfaces using a case study:a sodium–oxygen model battery.However,the use of APXPS in electrochemical studies is still in the early stages,so we summarize the current challenges and some developmental frontiers.Despite the challenges,we expect that joint efforts to improve instruments and the electrochemical setup will enable us to obtain a better understanding of the composition–reactivity relationship at electrochemical interfaces under realistic reaction conditions.
文摘In Bangladesh, both manual and e-GP system is used to perform public procurement. Before tender publication, tender documents have to be prepared by the Procurement Entities (PEs). The problem is that the manual tendering system involves more cost and time in preparing tender documents. The study’s purpose is to compare now the efficiency of tender document preparation in the manual system with the e-GP system. This study tests the cost and time involved in tender document preparation, both manual and e-procurement tenders. Sample data was collected from the 11 RHD zones. Structured survey questionnaires were used to collect primary data from the PE officers of RHD. A hypothesis test was performed using the model of independent samples t-test. The test results indicated that e-Procurement tender document preparation costs and time were less than manual tendering. Academicians, researchers, PE officers, and policymakers will benefit from the study’s conclusions.
文摘This paper discusses aspects related to competitiveness in the ITB (invitation to bid) of the public tender for the concession of the urban bus public transport services in the RMR (Metropolitan Region of Recife) in the Brazilian northeastern region. The bid was made public through a consortium formed by the two major cities of the RMR--Recife and Olinda, and the government of the State of Pernambuco. Throughout the paper, the basic features of the bidding terms are presented and some aspects of these characteristics that undermine competitiveness are pointed out and submitted to criticisms. Aspects such as the small number of lots, the lack of diversification of lot sizes and the possibility of forming consortia with unlimited number of participants were targeted. In order to prove the criticisms stated, a simulation of an arrangement amongst incumbents is presented, based on the rules of the tender, in which the allocation of incumbents ex post bidding does not differ from the ex ante scenario. Thus, the main objective of this article is to assess whether good practices that foster competition were followed by the ITB and the main conclusion is that competitiveness was put in jeopardy.
文摘Bangladesh’s public procurement system has been traditional, i.e., a manual tendering system, under the legislative guidance of PPA-2006 and PPR-2008. Manual tendering has long been a source of concern for public procurement agencies regarding tender opening related to cost and time. To resolve this challenge and make the dream of a Digital Bangladesh a reality, the Government of Bangladesh launched the e-Procurement system in 2011 under the flagship of e-GP Guidelines. Following the successful pilot testing conducted under the umbrella of the CPTU, all public PEs are attempting to implement electronic procurement tenders. This study aims to examine the cost and time involved in preparing Tender Opening Committee (TOC) Reports for manual and e-procurement tenders in Bangladesh’s Roads and Highways Department. A mixed-method was used to collect data from the population of 11 RHD zones, including KII and primarily survey questionnaires. The independent samples t-test was used to compare data and hypothesis tests from two groups using SPSS software. The results indicated that e-Procurement tendering, tender opening preparation costs and time were more efficient than manual tendering. Academicians, students, practitioners, researchers, and policymakers will benefit from the study’s conclusions. Additionally, the government will be urged to improve policies such as the PPA 2006, the PPR 2008, and the 2011 e-GP Guideline.
文摘Bidding is a key link during the implementation of a construction project.For the same construction project,there are usually multiple construction companies bidding together to obtain the right to contract for the project.However,there are still various irregularities in the bidding stage.This article analyzed the above problems and proposed a management strategy for the optimization of bidding,looking forward to improving the quality of bidding management of construction projects,solving various illegal bidding problems,and purifying the environment of bidding management.
文摘Objective' To study the muscular histological traits and their relationship with meat tenderness in local broilers and provide a theoretical basis for promoting meat quality of broiler. [Methed] The diameter and density of muscle fiber of three local varieties of chicken (Beijing Fatty broil- er, Fujian Hetian broiler and Taining Black broiler) were detected at the age of 8 weeks, 12 weeks and 16 weeks. And the differences in the diame- ter and density of muscle fiber as well as their relationship with meat tenderness were respectively analyzed with SAS software. [ Resultl Fatty broil- er had the smallest muscle fiber diameter while Hetian broiler the largest; Fatty broiler had the highest muscle fiber density while Hetian broiler the lowest Hetian broiler had the highest muscle shear force of leg muscle while Black broiler the lowest ( P 〈0.05) ; Black broiler had the highest mus- cle shear force of breast muscle while Fatty broiler the lowest (P〈0.05). The correlation analysis showed that the shear force of breast muscle and leg muscle had significantly positive relation with fiber diameter and significantly negative relation with fiber density ( P 〈 0.05). [ Conclusion] Muscu- lar histological traits varied in different local broilers, and the muscular shear force had significantly relation with fiber diameter and density.
基金Supported by Scientific Research Project of Jilin Education Department([2010]number450)~~
文摘[Objective] The study was carried out in order to find out the best method of rapid cutting rooting of Syriga microphylla with tender branches.[Method] Effect of rooting reagent with different concentrations on the rapid cutting rooting of Syriga microphylla with tender branches was studied in our paper.[Result] There was great difference between cuttings with auxin and without auxin.[Conclusion] Tender branches treated by 90 mg/L indole butyric acid(IBA)had the best cutting rooting.
文摘Two major apoptosis pathways have been defined in mammalian cells, the Fas/TNF-R1 death receptor pathway and the mitochondria pathway. The Bcl-2 family proteins consist of both anti-apoptosis and pro- apoptosis members that regulate apoptosis, mainly by controlling the release of cytochrome c and other mitochondrial apoptotic events. However, death signals mediated by Fas/TNF-R1 receptors can usually activate caspases directly, bypassing the need for mitochondria and escaping the regulation by Bcl-2 family proteins. Bid is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Activated Bid is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Such a connection between the two apoptosis pathways could be important for induction of apoptosis in certain types of cells and responsible for the pathogenesis of a number of human diseases.
基金University of Kerala,Thiruvananthapuram,India for financial Support
文摘Objective:To investigate whether tender coconut water(TCW) mitigates oxidative stress in fructose fed hypertensive rats.Methods:Male Sprague Dawley rats were fed with fructose rich diet and treated with TCW(4 mL/100 g of body weight) for 3 subsequent weeks.Systolic blootl pressure was measured every three days using the indirect tail cuff method.At the end of the experimental period,plasma glucose and insulin,serum triglycerides and free fatly acids, lipid peroxidation markers(MDA,hydroperoxides and conjugated dienes) and the activities of antioxidant enzymes were analyzed in all the groups.Results:Treatment with TCW significandy lowered the systolic blood pressure and reduced serum triglycerides and free fatty acids.Plasma glucose and insulin levels and lipid peroxidation markers such as MDA,hydroperoxides and conjugated dienes were significantly reduced in fructose fed rats treated with TCW.Activities of antioxidant enzymes are up regulated significantly in TCW treated rats.Hislopathological analysis of liver showed that TCW treatment reduced the lipid accumulation and inflammatory infiltration without any significant hepatocellular damage.Conclusions:The overall results suggest that, TCW treatment could prevent and reverse high blood pressure induced by high fructose diet probably by inhibition of lipid peroxidation,upregulation of antioxidant status and improved insulin sensitivity.
文摘Aging is a popular method used by meat industry for improving the sensory attributes of meat.Despite the advent of many novel technologies,aging has not lost its charm and is still widely used commercially as a post-mortem intervention for tenderization.Aging improves the tenderness of meat through disruption of the muscle structure by intracellular proteolytic systems.Muscles undergo various molecular changes that cause proteolysis of key myofibrillar and cytoskeletal proteins,disrupting the overall integrity of muscle cells.Although several endogenous proteolytic systems are capable of post-mortem proteolysis,a great body of scientific evidence supports a major role for the calpain system.Calpains are intracellular calcium-dependent cysteine proteases found in most eukaryotes.At least three calpains(μ-and m-calpains and calpain 3)and calpastatin,their specific endogenous inhibitor,are found in muscle.They are known to be involved in the proteolysis of functionally relevant structural proteins such as the myofibrillar proteins and cytoskeletal anchorage complexes.These ubiquitous proteases are also present in mitochondria and play important roles in a variety of pathophysiological conditions including apoptotic and necrotic cell death phenomena.This review discusses the role and contribution of the calpain system and the factors that influence calpain activity during aging.
文摘The development of deepwater oil fields has reached a new stage with the dramatic increase in water depth and the recent increasing demands of the economic development in the filed. The use of a Tension Leg Platform (TIP) combined with other systems, such as Floating Production Storage and Offloading (FPSO) system, Floating Production Unit (FPU) system, Tender Assisted Drilling (TAD) system, etc., has drawn the industry attention and increased significantly in the past few years. For the areas lacking of pipeline system, the use of TIP(s) combined with FPSO has been chosen to efficiently develop the deepwater fields. The TIP with a Tender Assisted Drilling system significantly reduces the payload of the platform and reduces the investment in the TIP system substantially. This opens the door for many new deepwater field developments to use the tension leg platform. The advantage of the TIP combined with a TAD system is more significant when several TIPs are used for the continuous development of the field. One of the applications for the TIP with a tender assisted drilling system can be in the development of an offshore marginal field. Owing to the increase of water depth, the conventional fixed platform model for the exploration of those fields becomes uneconomical. It also would be too expensive to use a large TIP structure for those marginal fields due to the large amount of initial investment. The TIP system with tender assisted drilling can be used to develop those fields economically. There are many marginal fields in China offshore, especially in shelf areas. The application of this field developing model, combined with the existing field developing experience in China, will open the door for many marginal field developments. This paper will review the application of the combined TIP system through some examples of completed/ongoing projects, and major technical issues encountered in those practices. The potential application of this technology in China deepwater development will be discussed in the end.
文摘The aim of this study was to determine the effects of age on chemical composition and tenderness of donkey meat. These characteristics were determined on Longissimus thoracis samples taken from 40 entire donkey males of Martina Franca breed slaughtered at 12 (Group 1, n = 20) and at 18 months (Group 2, n = 20) of age. Tenderness was evalu-ated at two and seven days post slaughter using a Warner-Bratzler shear force device. The chemical composition showed a significant increase in protein content (P < 0.05) in the meat of donkeys slaughtered at 18 months of age (22.3 g/100 g) compared to the meat of younger animals (21.4 g/100 g). Intramuscular fat content was significantly lower (P < 0.05) in Group 1 (2.41 g/100 g) compared to Group 2 (3.71 g/100 g). Shear force values at seven days post slaughter were significantly (P < 0.01) lower (5.15 ± 0.31 kg/cm2) in Group 1 compared with the results obtained at two days post slaughter (6.25 ± 0.53 kg/cm2). In Group 2 shear force values obtained seven days post mortem were higher (5.88 ± 0.23 kg/cm2) compared with Group 1 after the same ageing period but significantly (P < 0.05) lower if compared with those (6.53 ± 0.23 kg/cm2) determined in the same animals two days post slaugher.
基金supported by the National Natural Science Foundation of China(G32072142,31972099)。
文摘In this study,endoplasmic reticulum(ER)stress inducer tunicamycin(TM)and inhibitor 4-phenylbutyric acid(4-PBA)were used to treat postmortem chicken breast muscle to investigate changes in tenderness and effects on apoptosis and autophagy during 5 days ageing.TM-induced ER stress reduced shear force,enhanced myofibril fragmentation index(MFI),disrupted myofibril structure,increased desmin degradation,and activatedμ-calpain and caspase-12.In addition,TM-induced ER stress increased the expression of Bax,Bim,and cytochrome c,and decreased the expression of Bcl-x L.Furthermore,TM-induced ER stress improved the conversion of LC3I to LC3II,raised the expression of Beclin-1,and decreased the expression of p62,PI3K,and m TOR.The opposite results were observed after 4-PBA treatment.These results suggested that ER stress could improve chicken tenderness,promote apoptosis and autophagy during chicken postmortem ageing.
文摘This paper puts forward a new framework of multi-agent based equipment bidding system on the Web (MAEBSW). The purpose of the paper is to make the process of enterprise equipment bidding, especially the decision process of enterprise equipment bidding, more intelligent. The system discussed in this paper is an efficient method for the enterprises doing business electronically. We also present our opinion of the approaches to defining agents. We emphasize the importance of agent being able to provide explanation about its behavior for the user or other agents. Based on this opinion we design a new common architecture of most agents in MAEBSW.
基金Supported by Science and Technology Support Planning Project of Sichuan Province(2021YFYZ0031SASA2024CZYX002)National Modern Agricultural Technology System Construction of China(CARS-41-G07)。
文摘The calpain system is ubiquitous in cells, mainly comprising calpains and calpain inhibitors, and is a widespread calcium-dependent cysteine protease in organisms that is involved in many cellular processes such as muscle degradation in vivo and affects the tenderness of meat after animal slaughter. The study found 128 DEGs that probably regulated tenderness traits were selected from 16 significantly enriched GO terms by transcriptome sequencing analysis, and found that the developmental changes in the expression levels of the CAPN1 gene in the pectoral and leg muscles were significantly positively correlated ( P <0.05) with the cumulative growth values of live weight and comb weight. The developmental changes in the expression levels of the CAST gene in the pectoral and leg muscles were not significantly correlated with the cumulative growth values of live weight and comb weight. Our results helped demonstrate the potential molecular mechanisms of tenderness in chickens and provide valuable information for chicken breeding.