Analyses and Prediction of the Suitable Culture Period of Laver along the Coastal Areas of Jiangsu Province

[ Objective] The study aimed to analyze and predict the suitable period of laver along the coastal areas of Jiangsu Province. [ Method ] TO enhance the ability of meteorology to service laver culture, using the modern weather forecast technology, agricultural weather prediction was de- veloped according to the demands for meteorological conditions during laver production. [ Result] From south to north, there were certain differ- ences in the suitable periods of laver culture, breeding and harvesting, with slight variations. The forecast of the first and last days of certain water temperature could provide scientific references for the meteorological service of laver culture, and the service effect became better after it was modi- fied with the aid of the medium-term and long-term weather prediction. [ Conclusion] The research can offer theoretical bases for the culture of laver along the coastal areas of Jiangsu Province.

Exosomes derived from 3D-cultured MSCs improve therapeutic effects in periodontitis and experimental colitis and restore the Th17 cell/Treg balance in inflamed periodontium

Although mesenchymal stem cell-derived exosomes(MSC-exos)have been shown to have therapeutic effects in experimental periodontitis,their drawbacks,such as low yield and limited efficacy,have hampered their clinical application.These drawbacks can be largely reduced by replacing the traditional 2D culture system with a 3D system.However,the potential function of MSC-exos produced by 3D culture(3D-exos)in periodontitis remains elusive.This study showed that compared with MSC-exos generated via 2D culture(2D-exos),3D-exos showed enhanced anti-inflammatory effects in a ligature-induced model of periodontitis by restoring the reactive T helper 17(Th17)cell/Treg balance in inflamed periodontal tissues.Mechanistically,3D-exos exhibited greater enrichment of miR-1246,which can suppress the expression of Nfat5,a key factor that mediates Th17 cell polarization in a sequence-dependent manner.Furthermore,we found that recovery of the Th17 cell/Treg balance in the inflamed periodontium by the local injection of 3D-exos attenuated experimental colitis.Our study not only showed that by restoring the Th17 cell/Treg balance through the miR-1246/Nfat5 axis,the 3D culture system improved the function of MSC-exos in the treatment of periodontitis,but also it provided a basis for treating inflammatory bowel disease(IBD)by restoring immune responses in the inflamed periodontium.

Increased production of recombinant prourokinase with porous microcarrier cell culture by periodic pressure oscillation in a stirred tank reactor

An rCHO cell line expressing recombinant human prourokinase （pro-UK） at the level of 5μg/ 10^6cells/d was cultivated on Cytopore cellulose porous microcarriers in a 7.5L Biostat CT stirred tank reactor. A periodic pressure oscillation of 0.04 MPa and 0.04 Hz was adopted to introduce a physical stimulus on the rCHO cells and to improve mass transfer characteristic between cells and medium in the process of porous microcarrier CHO cell culture. Compared to constant pressure culture, the oscillation culture didn＇t influence specific cell growth rate significantly, but could enhance the pro-UK specific production by 10% - 40%, and reduce production of lactate by 10% - 30%. In the perfusion culture of recombinant CHO cell with serum-free medium for 67 days, cell density could reach 2.64×10^7/ml, the maximal prourokinase concentration in harvested supernatant was about 118mg/L, a total of 21.1 grams of prourokinase was produced in 313 liters of supernatant. In conclusion, the perfusion cell culture with periodic pressure oscillation can enhance the production of recombinant protein and increase the reactor specific productivity.

Natural Disasters of the Lower Reaches of Yellow River during the Longshan Period——The Natural Background of Dayu's Flood Control

It is very important to study the archaeological culture and origin of civilization in ancient China.The changes of the channels in the lower reaches of the Yellow River in the prehistoric period are part of the natural environmental background of the development of the ancient civilization in that area to be explored.This paper presents a series of legends,indications,scientific evidence,and macroscopic geographical background information of the evolution in the lower reaches of the Yellow River during the Longshan period.At first the river flowed from Northern Henan and Hebei to southwestern Shandong Province and Northern Anhui–Jiangsu provinces,and the mainstream of the Yellow River changed from the southeast to return to the north and flowed into the Bohai Sea in the late Longshan Period.During this period,floods were frequent.Various ethnic groups in the northern China plains suffered natural disasters and made great migrations which also contributed to the ethnic exchanges and integration.The people of the Central Plains made more dynamic adjustments in the relationship between mankind and the land by primitively escaping from the water and self–defensively controlling the rivers then to maintaining the local ecological environment by large–scale flood control measures,which promoted the settlement of Shandong,Henan,Jiangsu and Anhui provinces,the urban cultural development,and social evolution.Based on these events,the culture symbol of Dayu's Flood Control could be formed.

Connotations and Internal Cultural Meanings of Chinese Jade in Chu Culture at Pre-Qin Period

The thesis conducts its analysis fromthe perspective of cultural characteristics of Chu state of Pre-Qin period in ancient China.The culture of Chu,usually focusing on ceremony sacrifice and several other activities,presents unique characteristics of the development of Chinese society and culture.Actually,the jade artifact at that time shows cultural features both at artistic and spiritual level and bears prominent cultural connotations like national spirit of solemnness and generosity.Chinese jade of Chu state of Pre-Qin period due to its abundant cultural connotations and meanings,poses to be an essential element of traditional Chinese culture,which shows artistic and national features of traditional jade culture and can directly influence development of modern society and culture.

Social Classes and Cultural Connotations of Yangzhou Home Gardens during the Late Qing Dynasty and the Republic of China

During the late Qing Dynasty and the early period of the Republic of China(1870-1930),the social classes in Yangzhou were basically dominated by officials,businessmen,and scholars.In the building number,scale,and functional evolution of their home gardens,these three classes were different,reflecting abundant connotation of characteristic of the time and regional culture,revealing the inheritance path of Yangzhou culture,as well as the richness and diversity of home gardens in Yangzhou during the late Qing Dynasty and the early period of the Republic of China.

Celebrating Diversity of Humanity, Struggling for Peace, and Establishing Culture of Coexistence

The Qur＇an embraces cultural pluralism, emphasising that “People, We created you all from a single man and a single woman, and made you into races and tribes so that you should recognize one another. ”（Q. 49： 13）. Moreover, peace is the most fundamental value in the Qur＇an and Islam. The majority of the classical Muslim jurists, especially Hanafi school, emphasised that the reason for Muslims＇ fight against non-Muslims is Muslims＇ defense themselves against attacks, not non-Muslims＇ faith. Bediuzzaman Said Nursi （d. 1960） states that the only kind of jihad that is appropriate for the present age is spiritual or moraljihad. Furthermore, regarding Qur＇anic approach to relations between Muslims and the People of the Book, Muslim scholars, in general, advocate sincere relations and trust between Muslims and the People of the Book. In addition, Said Nursi is one of the great Muslim scholars in interfaith dialogue in the 20th century. Finally, there is the need for establishing culture of coexistence, which practised before within a religious tradition such as Islamic tradition for many centuries in the history. Through achieving a culture of coexistence and peace, most conflicts can be resolved.

Benchmarking gene set of gymnosperms for assessing genome and annotation completeness in BUSCO

Dear Editor,Gymnosperms,naked-seed plants,are phylogenetically sister to the flowering plants(angiosperms),of which the origin can be traced back to the Devonian period.Despite their f lourishing diversity in the Mesozoic era,only∼1000 living species of gymnosperms exist in the modern flora(∼0.4%of the number of angiosperms)[1].However,they account for at least 39%of the world’s forests[2]and hold great economic and cultural importance in horticulture,medicine,and the timber industry[3].

先秦时期生态文化述论

先秦时期是中华民族的先民在中华大地上筚路蓝缕、开疆扩土、探索生态环境并协调人与自然关系的早期阶段。在该阶段,中华大地优越的生境保证了先民的稳态延续,而先民在与纷繁的自然环境互动的同时也创造了灿烂的生态文化。如钻木取火和刀耕火种提高了生计水平,治水保卫了生境安全,历法和节气提高了人们对自然规律的掌握,生态保护律法减小了对环境的破坏力度,专门的生态论著则使生态保护上升到哲学的高度等。而其中蕴含的敬畏自然、艰苦探索、遵德循礼、居安思危的生态理念维护了先秦时期人与自然的和谐共生。这些生态文化尽管历史久远,但是仍对我国新时代生态文明建设留下了宝贵的精神财富,赋予了诸多参考和借鉴的意义。

艺术考古视角下的仰韶文化半坡类型分期

艺术考古依据艺术发展的一般规律展开研究,在分期研究上可以形成不同于考古类型学的新的认识。从该视角出发重新审视仰韶文化半坡类型的彩陶材料,根据其彩陶纹饰的先后发展序列以及纹饰风格的发展规律,可以重建半坡类型的发展阶段(将姜寨一期的文化特征视为半坡类型的开始),并由此揭示仰韶文化早期各个阶段的文化特征。艺术考古方法作为一种新的研究手段,更关注艺术图像和风格的变化及其关联因素,有助于深入理解史前社会的性质和文化特性。

民国时期四川体育期刊研究

民国时期,四川先后至少发行过9种体育期刊,这些期刊是探究民国初期和抗战时期,四川、西南地区,乃至全国体育发展状况的重要文献来源。文章依托原始文献,运用内容分析法,对民国时期四川发行的体育期刊进行综合考察。研究发现,四川发行的体育期刊有其独特的特点:(1)体育期刊出现的时间相对较早,时间跨度较大;(2)体育期刊种类相对较多,但期数较少;(3)作者群中体育精英云集;(4)突出体育救国,重视战时体育和国防体育。在期刊对体育发展的影响方面,主要体现在五个方面:(1)注重学术研究,促进了体育理论探索的深入和体育知识、常识的普及;(2)重视体育教育,推动了学校体育的进步;(3)关注体育动态,促进了体育信息的交流和传播;(4)重视体育历史,促进了体育史研究的发展;(5)注重经验总结,促进了政府和民众对体育重要性的认识。

延安时期中国共产党的红色文化国际传播工作探赜

延安时期,为获取国际社会支持、塑造先进政党形象以及发挥红色文化作用,中国共产党积极开展红色文化国际传播工作。为此,中国共产党以新民主主义革命理论成果、红色精神和革命文艺作品等红色文化作为主要内容,通过创办报刊、设立电台、接待外国记者等方式,积极向外传播红色文化,开创了文化外交新局面,取得了显著成效:加深了国际社会对中国共产党的认识和理解、扩大了国际社会对中国抗战的支持和援助、推动了这一时期中外文化的交流与合作。彼时党的红色文化国际传播工作为当今讲好中国故事、促进中华文化“走出去”留下了宝贵经验:坚持中国共产党文化国际传播事业的领导权、丰富国际交流中的文化传播方式、坚定不移走和平发展的文化国际传播道路。

日据时期朝鲜半岛鲁迅作品译介的思想谱系与文化抉择--以《狂人日记》和《阿Q正传》的韩译为例

《狂人日记》和《阿Q正传》分别于1927年和1930年译介至日据时期的朝鲜半岛。两部作品韩译本虽然在翻译质量上均存在诸多无法忽视的缺陷,但是柳树人翻译的《狂人日记》作为世界上首部由外国译者翻译成外文并在国外发表的鲁迅作品,开启了外国译者翻译鲁迅作品的先河;梁建植翻译的《阿Q正传》作为朝鲜半岛众多韩译本中的首部作品,也在“阿Q”形象传播接受方面厥功甚伟。从译者思想谱系来看,幼时阅读《狂人日记》的思想冲击以及后来的无政府主义转向,促成了柳树人与鲁迅在无政府主义思想基点上达成了共通的文艺启蒙理论共识,成为译介《狂人日记》的内在契机。而梁建植翻译的《阿Q正传》尽管受制于日本殖民文化霸权而不得不借助于井上红梅的日译本进行转译和“译述”,但这恰恰体现了梁建植将殖民地宗主国语言--日语--为我所用的文化立场,以及即使通过迂回和曲折的方式,也要关注和译介中国新文学的文化抉择。

清代宫廷里的西药与西药房研究

故宫包含了极为丰富的文化。本文研究了清康熙时期的几种典型西药,以及宫中设立的西药房,以探讨清代宫廷里的东西方医药文化融合。结果表明:德里鸦噶可以驱寒及化疹,巴尔撒木油可以治疗刀伤,如勒伯伯尔拉都可以补气养胃,宫中养心殿曾作为西药研发的“实验室”,武英殿露房曾作为西药的“药房”。

数字人文视域下新文化运动时期知识分子的情感演化研究——以《新青年》杂志为例

文章从数字人文视角出发,以《新青年》杂志为例,分析了新文化运动时期知识分子的情感演化历程及外部动因,为研究特定历史时期思想政治文化格局的演变提供研究思路与案例支持。基于已有的分类框架,本研究将《新青年》杂志1915—1922年所刊发的文章划分为“政治文化”“哲学思潮”“社会教育”“语言文学”共4个类目,对每个类目的文章内容进行统计和分析,获取了文章作者、发文时间、主题词、涉及人物等基本数据以及文章的情感极性和强度。然后分别对每个类目所涉人物进行聚类,并从群体(类目总体情感演化)和个体(代表性人物的跨类目比较)两个角度分析了五四运动前后人物情感演化过程及特征。最后,结合文章主题和具体历史事件探讨了人物情感演化的外部动因,从而对该历史时期的人文风貌及社会变迁进行客观呈现。

明清之际文化转型中的经世实学——兼谈《虚实之辨:颜元的问题意识及其哲学展开》一书的新探索

17世纪中叶,亦即通常所说的明清之际,中国思想文化史上出现了顾炎武、黄宗羲、王夫之、方以智、李颙、傅山、颜元等一大批极富批判个性的思想家。他们对中国古代后期封建宗法社会君权政治及其思想意识形态进行了总体性的批判与重构,开启了封建文化内部的自我批判与时代转型。颜元实学思想是这一时期思想文化史上的一枝奇葩。

认知性访谈在过渡期炎症性肠病患者过渡准备量表文化调适中的应用

目的 应用认知性访谈探讨过渡期炎症性肠病患者过渡准备量表(Transition Readiness Measure,TRM)的认知与领悟,就中文版过渡准备量表中的语义等内容再次进行测试。方法 采用目的抽样法,选取上海市2所三级甲等医院就诊的18例处于过渡期的炎症性肠病患者,共开展3轮认知性访谈,了解其对中文版过渡准备量表初稿的认知,并结合专家小组意见,对存在歧义的条目进行修订,形成中文版过渡准备量表。结果 第1轮访谈结果表明,部分受访者对中文版过渡准备量表中的4个条目的表达和理解有歧义;第2轮访谈结果表明,2例受访者对其中1个条目的表达和理解有歧义;第3轮访谈结果表明,受访者均能正确地理解修订后的各个条目,保持与源量表语义的一致性。结论 认知性访谈基于患者视角进一步修订量表,促进受访者对中文版量表内容理解的一致性,有助于提高量表的科学性、适用性和准确性。

南京民国建筑基因提取及智能辅助创新设计研究

目的基于对南京民国建筑文化进行保护的视角,探寻南京民国建筑基因的现代设计传承路径,挖掘人工智能辅助南京民国建筑主题文创产品设计的新思路。方法首先,选择25处代表性南京民国建筑作为研究对象,根据建筑基因理论解析南京民国建筑基因的类型,对立面样式、屋顶造型、装饰纹样、色彩搭配、建筑材料、空间环境、情感因素7类基因进行图谱绘制;其次,运用层次分析法对基因图谱进行权重计算并选取设计因子;再次,使用形状文法重构设计因子,将演变后的设计因子输入人工智能软件并生成50张纹样图形样本;最后,基于SOR理论模型进行实验评价,选出智能生成纹样中最符合南京民国建筑风格的样本并应用于文创设计之中。结果构建南京民国建筑基因图谱及判断矩阵评价模型,选取典型因子并采用人工智能软件生成纹样,形成了文创智能化设计新模式。结论对南京民国建筑基因提取及智能辅助设计进行研究,展示了南京民国建筑基因所具备的遗传、选择、复制、变异等特性,实现了建筑遗产的创造性转化、创新性发展,同时显示了智能辅助文创设计的可能性,提升了文创产品的文化内涵。

形式、器具、术语与言行:近代报刊中的茶馆文化

近代报刊作为历史的见证,为我们保留了大量关于茶馆的珍贵记载。本文旨在挖掘这些丰富的资料,从历史的视角分析茶馆文化在近代报刊中的呈现。形式上,近代茶馆的饮茶方式展现出鲜明的地域特色,在不同时期的不同地区存在显著差异,反映了各地人们的生活习惯和口味偏好;器具方面,茶馆中的茶具不仅是人们生活习惯和文化传统的体现,更是一种社会历史文化镜像,反映出当时的社会风貌、经济状况以及物质文化变迁;术语方面,茶馆作为特定场所,有着独特的语言交流方式,通过对各类茶馆术语的梳理,我们可以窥见茶馆文化的独特魅力和深厚底蕴;言行方面,茶馆中的言行有其特殊意义,不仅是人们分享彼此、交流情感的方式,还能起到普及知识、道德教化、舆论监督和情感纽带的作用。