期刊文献+
共找到4,589篇文章
< 1 2 230 >
每页显示 20 50 100
从协同到求异:指向教师专业发展的U-S合作优化研究 被引量:1
1
作者 汪明帅 杨扬 《教师发展研究》 2024年第2期83-90,共8页
U-S合作是教师专业发展的重要举措。审视U-S合作的历程可知,U-S合作致力于多方位促进教师专业发展,协同逐渐成为U-S合作促进教师专业发展的底层逻辑。随着合作的持续推进,这一底层逻辑在促进教师专业发展方面所潜在的矛盾也逐渐暴露出... U-S合作是教师专业发展的重要举措。审视U-S合作的历程可知,U-S合作致力于多方位促进教师专业发展,协同逐渐成为U-S合作促进教师专业发展的底层逻辑。随着合作的持续推进,这一底层逻辑在促进教师专业发展方面所潜在的矛盾也逐渐暴露出来。一方面,大学与中小学的文化差异阻碍了协同的深度发生;另一方面,为了实现大学与中小学的协同,双方不得不做出诸多的妥协,在妥协的语境下,中小学教师往往面临着主体性丧失的风险。与之相对,在求异这一核心理念的引领下,跨界学习旗帜鲜明地提出了“差异即资源”的主张,并通过互动场域的营造和互动系统的建构,为“差异即资源”提供了现实可能,也为优化U-S合作提供了新的思路。 展开更多
关键词 u-s合作 教师专业发展 协同 求异
下载PDF
“U-S”合作中高校教师与中小学教师的跨界知识互动探究
2
作者 陆超 《现代基础教育研究》 2024年第3期27-31,共5页
对于“U-S”合作情境中高校教师与中小学教师如何进行知识互动这一重要问题,鲜有实证研究涉及。通过对高校与中小学合作的多个案例进行质性研究,发现高校教师与中小学教师的知识互动存在三种不同的模式:一是高校教师主导下的知识迁移模... 对于“U-S”合作情境中高校教师与中小学教师如何进行知识互动这一重要问题,鲜有实证研究涉及。通过对高校与中小学合作的多个案例进行质性研究,发现高校教师与中小学教师的知识互动存在三种不同的模式:一是高校教师主导下的知识迁移模式,二是内化与重构后的知识转化模式,三是基于研究伙伴关系的知识生产模式。基于此,自我定位与地位关系、知识互动的聚焦性和持续性、卷入程度及跨界互动能力,是影响高校教师与中小学教师知识互动效果的重要因素。 展开更多
关键词 u-s”合作 跨界知识互动 知识生产
下载PDF
Community-led total sanitation(CLTS)implementation in West Mamprusi Municipal Assembly in Ghana.What do communities think eleven years on?
3
作者 Elijah Adam Emmanuel Badu 《Global Health Journal》 2024年第2期67-73,共7页
Objective Access to improved sanitation is a fundamental human right and an important aspect of Public Health.However,an estimated thousands of people in Ghana especially,the West Mamprusi Municipal Assembly(WMMA)stil... Objective Access to improved sanitation is a fundamental human right and an important aspect of Public Health.However,an estimated thousands of people in Ghana especially,the West Mamprusi Municipal Assembly(WMMA)still have no access to adequate toilet facilities.This has brought untold health repercussions to the inhabitants,the community,and the environment at large.To address this menace,the community-led total sanitation(CLTS)was implemented.This study aimed to assess communities’perspectives on the implementation of CLTS and to understand the factors influencing its success and failures.Methods A mixed-method approach involving sequential qualitative and quantitative methods was employed in this study.Participants for the quantitative study were randomly selected and surveyed using questionnaires.The qualitative study employed focus group discussion involving purposively sampled participants including assembly members,opinion leaders,and assembly staff.Results The CLTS program in WMMA realized an apparent use of construction and proper use of household latrines leading to a reduction of open defecation free(ODF)and two communities achieving sanitized status in the history of the study area,enabling the training of latrine artisans and natural leaders to facilitate the CLTS expansion and sustainability,improved sanitation and hygiene,strengthened the enforcement of community rules and regulations and many others.Conclusion The CLTS program has received more widespread acceptance in the study area than the previous government policy of constructing public toilets,which was greeted with massive failures due to poor implementation.To ensure that gains achieved through CLTS implementation are sustained longer,it is recommended that chiefs and opinion leaders should be involved in the CLTS programs to ensure checks and enforcement.The entrenchment of bylaws and more education to address enduring myths and misconceptions will sustain the program.Subsidies in the form of sanitation loans for latrine construction materials by the government and supporting non-governmental organizations(NGOs)will be paramount in sustaining ODF. 展开更多
关键词 community-led total sanitation(CLTS) community development Ghana SANITATION
下载PDF
U-S合作框架下在职教师校本培训模式的创新实践
4
作者 喻洁 《教育进展》 2024年第1期273-278,共6页
培训课程内容与需求脱节、培训观念及培训方式不够多元、合作机制不健全是教师教育U-S合作普遍存在的三大问题。通过多元化的培训方式,按照“提前诊断,明确学校问题→深入调研,了解培训需求→以校为本,确定培训内容→促进共赢,充分利用... 培训课程内容与需求脱节、培训观念及培训方式不够多元、合作机制不健全是教师教育U-S合作普遍存在的三大问题。通过多元化的培训方式,按照“提前诊断,明确学校问题→深入调研,了解培训需求→以校为本,确定培训内容→促进共赢,充分利用异质资源→长期合作,促进常态合作”的行动流程开展在职教师校本培训,可以有效提高教师教育U-S合作框架下教师培训的质量。这种新模式的突出特征在于以校为本、合作共赢和可持续性,不仅能够改善校本培训存在的问题,还能有效促进在职教师的成长。 展开更多
关键词 u-s合作 在职教师 校本培训
下载PDF
Analysis of Distribution of Public Toilets within Walking Range around Communities of the Elderly under the Model of Community Home-based Care for the Elderly: A Case Study of Changxindian, Fengtai District, Beijing
5
作者 TIAN Jiaqi ZHANG Miao HU Yan 《Journal of Landscape Research》 2024年第2期35-37,41,共4页
In recent years,under the influence of multiple factors such as traditional ideas and living economic conditions,the aging population in China continues to increase.Most of the elderly are more inclined to aged at hom... In recent years,under the influence of multiple factors such as traditional ideas and living economic conditions,the aging population in China continues to increase.Most of the elderly are more inclined to aged at home,and the first places for elderly activities are communities and the surrounding environment,which greatly affects the convenience of life and happiness of the elderly.In this paper,Changxindian area in Fengtai District of Beijing was as the research object,and detailed calculation and analysis were carried out by using POI data and arcGIS software.The relative location of residential areas and surrounding public toilets was explored,and the best location of public toilets in the daily walking area under the model of community home-based care for the elderly was further studied. 展开更多
关键词 Home-based care for the elderly The elderly Public toilets community
下载PDF
U-S协同合作培养小教师范生的教学模式研究
6
作者 曾丽丽 《中文科技期刊数据库(全文版)教育科学》 2024年第2期0020-0023,共4页
U-S协同合作为小教师范生的培养提供了新思路,也为小教师范生培养的教学模式创新产生了极大的影响。和传统教学模式中重理论轻实践、教学方式“一刀切”、跨学科交流不足、教学评价单一等问题相比,U-S协同合作则可以有效规避这些问题,... U-S协同合作为小教师范生的培养提供了新思路,也为小教师范生培养的教学模式创新产生了极大的影响。和传统教学模式中重理论轻实践、教学方式“一刀切”、跨学科交流不足、教学评价单一等问题相比,U-S协同合作则可以有效规避这些问题,并且引导小教师范生树立终身学习的理念。因此,高校应当积极进行策略探讨,通过构建共同目标、整合教学资料、强化教学实践、优化师资队伍等措施,推动培养小教师范生教学模式的改革与实施。 展开更多
关键词 u-s协同合作 小教师范生 教学模式 小学教育
下载PDF
智慧环境下的“U-S双师”课堂:设计、实施与评价 被引量:4
7
作者 刘喆 《电化教育研究》 北大核心 2023年第7期75-81,106,共8页
为破解教师教育者缺乏中小学教学经验、师范生在真实情境中实践机会有限等问题,文章基于协同创新和深度学习理论,系统构建了智慧环境下的“U-S双师”课堂教学设计框架,提出网络直播、真情境教学和课例展示三种双师课堂实施路径以及表现... 为破解教师教育者缺乏中小学教学经验、师范生在真实情境中实践机会有限等问题,文章基于协同创新和深度学习理论,系统构建了智慧环境下的“U-S双师”课堂教学设计框架,提出网络直播、真情境教学和课例展示三种双师课堂实施路径以及表现性评价设计步骤,并将其用于实践,开展行动研究。文章认为,智慧环境下的“U-S双师”课堂具有师生协同的互惠性、教学过程的进阶性和学习环境的智能性,是高校教师教育者与中小学教师共同开发课程内容,通过线上线下联袂执教或线下共同教学等形式,为师范生提供多元参与体验和个性化指导机会,促进师范生知识迁移、问题解决和实践创新的一种课堂形态。实践表明,师范生肯定“U-S双师”课堂的教育价值,能够积极参与并顺利完成学习任务,获得较为扎实的数学教学知识,形成创新思维能力和自我发展能力,但是评课交流方面的高阶思维能力亟待加强。 展开更多
关键词 u-s双师”课堂 教学设计 实施路径 表现性评价
下载PDF
“U-S”协作引领小学“三课”联动校本研修模式的实践探索 被引量:4
8
作者 韦芳 邓琴 石秋香 《河池学院学报》 2023年第1期57-66,共10页
校本研修是中小学教师群体成长的重要路径。引领与提升中小学校本研修质量,助力基础教育高质量发展,是地方高校服务地方基础教育的责任担当。河池学院基于地缘优势,依托高校专家资源和学术资源,深度推进与区域小学“U-S”协作,以“教学... 校本研修是中小学教师群体成长的重要路径。引领与提升中小学校本研修质量,助力基础教育高质量发展,是地方高校服务地方基础教育的责任担当。河池学院基于地缘优势,依托高校专家资源和学术资源,深度推进与区域小学“U-S”协作,以“教学即研究,成果即成长”为研修理念,探索构建课程理解、课例研究、课题指导为路径的“三课”联动校本研修模式,有效促进小学学科课堂教学改进,提升教师教科研能力,推动教师群体的专业成长和学校特色发展。 展开更多
关键词 u-s”协作 小学 校本研修 课程理解 课例研究 课题指导 教师专业发展
下载PDF
U-S教师共同体合作机制审思———基于知识管理的视角
9
作者 杜霞 张星 《集美大学学报(教育科学版)》 2023年第1期37-43,共7页
20世纪末大量兴起的区域教师共同体为教师专业发展创造了切实可行的路径,但在共同体实际合作中也存在着知识流动不平等、实践与理论割裂、合作机制固化等亟待解决的问题。20世纪90年代提出的知识管理的SECI模型建构了两种知识交互的四... 20世纪末大量兴起的区域教师共同体为教师专业发展创造了切实可行的路径,但在共同体实际合作中也存在着知识流动不平等、实践与理论割裂、合作机制固化等亟待解决的问题。20世纪90年代提出的知识管理的SECI模型建构了两种知识交互的四种模式,并以此来解释显性知识和隐性知识的相互作用,从而分析知识的流动与转化过程。将知识管理的手段运用在U-S教师共同体合作中,能够为解决合作中的困境与难题提供新的思路,为教师共同体实现真正意义上的知识共享与交流谋求可行性路径。 展开更多
关键词 u-s教师共同体 知识管理 SECI模型
下载PDF
右江盆地大际山U-(Mo)矿床围岩蚀变特征及微量元素迁移规律——对区域内U、Au成生关系的指示
10
作者 田建吉 刘畅 +1 位作者 吴玉 李秋实 《世界核地质科学》 CAS 2024年第3期434-449,共16页
位于扬子地块西南缘的右江盆地,是全球第二大的卡林型Au矿(共伴生有Sb、Hg、Tl异常/矿化)矿集区,有着滇黔桂“金三角”的美誉。值得注意的是,该区除发育Au(-Sb-Hg-Tl)矿床外,还产有大量赋矿岩性和控矿构造相似的U矿床(点),成矿特色鲜明... 位于扬子地块西南缘的右江盆地,是全球第二大的卡林型Au矿(共伴生有Sb、Hg、Tl异常/矿化)矿集区,有着滇黔桂“金三角”的美誉。值得注意的是,该区除发育Au(-Sb-Hg-Tl)矿床外,还产有大量赋矿岩性和控矿构造相似的U矿床(点),成矿特色鲜明。前人对该区Au矿开展了大量研究,而U矿研究较少,对U、Au的成生关系尚不清楚。基于此,文章选取右江盆地内典型的U矿床——大际山U-(Mo)矿床为研究对象,通过开展岩矿相学研究和地球化学分析,厘定了矿化的围岩蚀变为硫化、沥青质化、磷铝锶石化、硅化和伊利石化,揭示了矿化过程中Re、Tl、Mo、U、Cd、Ni、Co、As、Sb、MREE的相对富集。蚀变矿物组合及元素迁移规律约束大际山U-(Mo)矿床中成矿物质可能来源于牛蹄塘组,成矿流体应为还原性有机流体与地表-近地表酸性、氧化性流体的混合,矿质沉淀发生在低温、酸性、还原环境中。综合分析认为,右江盆地内U、Au分布特征及矿床成因具有明显差异,二者应是不同成矿事件的产物。 展开更多
关键词 围岩蚀变特征 元素迁移规律 大际山u-(Mo)矿床 U、Au成生关系 右江盆地
下载PDF
Nontraditional energy-assisted mechanical machining of difficult-to-cut materials and components in aerospace community:a comparative analysis 被引量:2
11
作者 Guolong Zhao Biao Zhao +5 位作者 Wenfeng Ding Lianjia Xin Zhiwen Nian Jianhao Peng Ning He Jiuhua Xu 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2024年第2期190-271,共82页
The aerospace community widely uses difficult-to-cut materials,such as titanium alloys,high-temperature alloys,metal/ceramic/polymer matrix composites,hard and brittle materials,and geometrically complex components,su... The aerospace community widely uses difficult-to-cut materials,such as titanium alloys,high-temperature alloys,metal/ceramic/polymer matrix composites,hard and brittle materials,and geometrically complex components,such as thin-walled structures,microchannels,and complex surfaces.Mechanical machining is the main material removal process for the vast majority of aerospace components.However,many problems exist,including severe and rapid tool wear,low machining efficiency,and poor surface integrity.Nontraditional energy-assisted mechanical machining is a hybrid process that uses nontraditional energies(vibration,laser,electricity,etc)to improve the machinability of local materials and decrease the burden of mechanical machining.This provides a feasible and promising method to improve the material removal rate and surface quality,reduce process forces,and prolong tool life.However,systematic reviews of this technology are lacking with respect to the current research status and development direction.This paper reviews the recent progress in the nontraditional energy-assisted mechanical machining of difficult-to-cut materials and components in the aerospace community.In addition,this paper focuses on the processing principles,material responses under nontraditional energy,resultant forces and temperatures,material removal mechanisms,and applications of these processes,including vibration-,laser-,electric-,magnetic-,chemical-,advanced coolant-,and hybrid nontraditional energy-assisted mechanical machining.Finally,a comprehensive summary of the principles,advantages,and limitations of each hybrid process is provided,and future perspectives on forward design,device development,and sustainability of nontraditional energy-assisted mechanical machining processes are discussed. 展开更多
关键词 difficult-to-cut materials geometrically complex components nontraditional energy mechanical machining aerospace community
下载PDF
Implication of community-level ecophysiological parameterization to modelling ecosystem productivity:a case study across nine contrasting forest sites in eastern China 被引量:1
12
作者 Minzhe Fang Changjin Cheng +2 位作者 Nianpeng He Guoxin Si Osbert Jianxin Sun 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期1-11,共11页
Parameterization is a critical step in modelling ecosystem dynamics.However,assigning parameter values can be a technical challenge for structurally complex natural plant communities;uncertainties in model simulations... Parameterization is a critical step in modelling ecosystem dynamics.However,assigning parameter values can be a technical challenge for structurally complex natural plant communities;uncertainties in model simulations often arise from inappropriate model parameterization.Here we compared five methods for defining community-level specific leaf area(SLA)and leaf C:N across nine contrasting forest sites along the North-South Transect of Eastern China,including biomass-weighted average for the entire plant community(AP_BW)and four simplified selective sampling(biomass-weighted average over five dominant tree species[5DT_BW],basal area weighted average over five dominant tree species[5DT_AW],biomass-weighted average over all tree species[AT_BW]and basal area weighted average over all tree species[AT_AW]).We found that the default values for SLA and leaf C:N embedded in the Biome-BGC v4.2 were higher than the five computational methods produced across the nine sites,with deviations ranging from 28.0 to 73.3%.In addition,there were only slight deviations(<10%)between the whole plant community sampling(AP_BW)predicted NPP and the four simplified selective sampling methods,and no significant difference between the predictions of AT_BW and AP_BW except the Shennongjia site.The findings in this study highlights the critical importance of computational strategies for community-level parameterization in ecosystem process modelling,and will support the choice of parameterization methods. 展开更多
关键词 BIOME-BGC community traits Forest Ecosystems Model parameterization
下载PDF
Manure substitution improves maize yield by promoting soil fertility and mediating the microbial community in lime concretion black soil 被引量:1
13
作者 Minghui Cao Yan Duan +6 位作者 Minghao Li Caiguo Tang Wenjie Kan Jiangye Li Huilan Zhang Wenling Zhong Lifang Wu 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期698-710,共13页
Synthetic nitrogen(N)fertilizer has made a great contribution to the improvement of soil fertility and productivity,but excessive application of synthetic N fertilizer may cause agroecosystem risks,such as soil acidif... Synthetic nitrogen(N)fertilizer has made a great contribution to the improvement of soil fertility and productivity,but excessive application of synthetic N fertilizer may cause agroecosystem risks,such as soil acidification,groundwater contamination and biodiversity reduction.Meanwhile,organic substitution has received increasing attention for its ecologically and environmentally friendly and productivity benefits.However,the linkages between manure substitution,crop yield and the underlying microbial mechanisms remain uncertain.To bridge this gap,a three-year field experiment was conducted with five fertilization regimes:i)Control,non-fertilization;CF,conventional synthetic fertilizer application;CF_(1/2)M_(1/2),1/2 N input via synthetic fertilizer and 1/2 N input via manure;CF_(1/4)M_(3/4),1/4 N input synthetic fertilizer and 3/4 N input via manure;M,manure application.All fertilization treatments were designed to have equal N input.Our results showed that all manure substituted treatments achieved high soil fertility indexes(SFI)and productivities by increasing the soil organic carbon(SOC),total N(TN)and available phosphorus(AP)concentrations,and by altering the bacterial community diversity and composition compared with CF.SOC,AP,and the soil C:N ratio were mainly responsible for microbial community variations.The co-occurrence network revealed that SOC and AP had strong positive associations with Rhodospirillales and Burkholderiales,while TN and C:N ratio had positive and negative associations with Micromonosporaceae,respectively.These specific taxa are implicated in soil macroelement turnover.Random Forest analysis predicted that both biotic(bacterial composition and Micromonosporaceae)and abiotic(AP,SOC,SFI,and TN)factors had significant effects on crop yield.The present work strengthens our understanding of the effects of manure substitution on crop yield and provides theoretical support for optimizing fertilization strategies. 展开更多
关键词 FERTILIZATION manure substitution soil fertility maize yield bacterial community
下载PDF
Insights into microbiota community dynamics and flavor development mechanism during golden pomfret(Trachinotus ovatus)fermentation based on single-molecule real-time sequencing and molecular networking analysis 被引量:1
14
作者 Yueqi Wang Qian Chen +5 位作者 Huan Xiang Dongxiao Sun-Waterhouse Shengjun Chen Yongqiang Zhao Laihao Li Yanyan Wu 《Food Science and Human Wellness》 SCIE CSCD 2024年第1期101-114,共14页
Popular fermented golden pomfret(Trachinotus ovatus)is prepared via spontaneous fermentation;however,the mechanisms underlying the regulation of its flavor development remain unclear.This study shows the roles of the ... Popular fermented golden pomfret(Trachinotus ovatus)is prepared via spontaneous fermentation;however,the mechanisms underlying the regulation of its flavor development remain unclear.This study shows the roles of the complex microbiota and the dynamic changes in microbial community and flavor compounds during fish fermentation.Single-molecule real-time sequencing and molecular networking analysis revealed the correlations among different microbial genera and the relationships between microbial taxa and volatile compounds.Mechanisms underlying flavor development were also elucidated via KEGG based functional annotations.Clostridium,Shewanella,and Staphylococcus were the dominant microbial genera.Forty-nine volatile compounds were detected in the fermented fish samples,with thirteen identified as characteristic volatile compounds(ROAV>1).Volatile profiles resulted from the interactions among the microorganisms and derived enzymes,with the main metabolic pathways being amino acid biosynthesis/metabolism,carbon metabolism,and glycolysis/gluconeogenesis.This study demonstrated the approaches for distinguishing key microbiota associated with volatile compounds and monitoring the industrial production of high-quality fermented fish products. 展开更多
关键词 Fermented golden pomfret Microbiota community Volatile compound Co-occurrence network Metabolic pathway
下载PDF
Community structure and species diversity dynamics of a subtropical evergreen broad-leaved forest in China:2005 to 2020 被引量:1
15
作者 Shi-Guang Wei Lin Li +3 位作者 Kun-Dong Bai Zhi-Feng Wen Jing-Gang Zhou Qin Lin 《Plant Diversity》 SCIE CAS CSCD 2024年第1期70-77,共8页
Here,we characterize the temporal and spatial dynamics of forest community structure and species diversity in a subtropical evergreen broad-leaved forest in China.We found that community structure in this forest chang... Here,we characterize the temporal and spatial dynamics of forest community structure and species diversity in a subtropical evergreen broad-leaved forest in China.We found that community structure in this forest changed over a 15-year period.Specifically,renewal and death of common species was large,with the renewal of individuals mainly concentrated within a few populations,especially those of Aidia canthioides and Cryptocarya concinna.The numbers of individual deaths for common species were concentrated in the small and mid-diameter level.The spatial distribution of community species diversity fluctuated in each monitoring period,showing a more dispersed diversity after the 15-year study period,and the coefficient of variation on quadrats increased.In 2010,the death and renewal of the community and the spatial variation of species diversity were different compared to other survey years.Extreme weather may have affected species regeneration and community stability in our subtropical monsoon evergreen broad-leaved forests.Our findings suggest that strengthening the monitoring and management of the forest community will help better understand the long-and short-term causes of dynamic fluctuations of community structure and species diversity,and reveal the factors that drive changes in community structure. 展开更多
关键词 community structure Death and renewal dynamics Species diversity dynamics South subtropical forest
下载PDF
咖啡因通过FAK/AKT/ROCK通路调控人脑胶质瘤U-373MG细胞的恶性生物学行为
16
作者 徐加志 张芸 +5 位作者 陈大刚 高风全 任德帅 吴卫东 杜妍 王娜 《中国肿瘤生物治疗杂志》 CAS CSCD 北大核心 2024年第6期573-578,共6页
目的:探讨咖啡因通过调节FAK/AKT/ROCK信号通路来影响人脑胶质瘤U-373MG细胞的增殖、迁移和侵袭能力。方法:常规培养U-373MG细胞,将其分为对照组、咖啡因低剂量(1 mmol/L)组、咖啡因高剂量(2 mmol/L)组、PF573228组(FAK抑制剂,1μmol/L... 目的:探讨咖啡因通过调节FAK/AKT/ROCK信号通路来影响人脑胶质瘤U-373MG细胞的增殖、迁移和侵袭能力。方法:常规培养U-373MG细胞,将其分为对照组、咖啡因低剂量(1 mmol/L)组、咖啡因高剂量(2 mmol/L)组、PF573228组(FAK抑制剂,1μmol/L)、咖啡因高剂量+SC79组(AKT激活剂,8mg/L)。用CCK-8法、Transwell小室实验、流式细胞术和WB法分别检测各组U-373MG细胞的增殖、迁移、侵袭及凋亡,以及U-373MG细胞中p-FAK、p-AKT、p-ROCK、Ki67、MMP-9蛋白表达水平。建立U-373MG细胞裸鼠移植瘤模型,观察咖啡因对移植瘤生长的影响,WB法检测移植瘤组织中相关蛋白的表达。结果:咖啡因、PF573228可显著抑制U-373MG细胞的增殖、迁移、侵袭能力,促进U-373MG细胞凋亡,抑制p-FAK、p-AKT、p-ROCK、Ki67、MMP-9蛋白的表达(均P<0.05),SC79则可部分逆转咖啡因对U-373MG细胞的作用(均P<0.05)。咖啡因可显著抑制移植瘤的生长及移植瘤组织中上述相关蛋白的表达(均P<0.05)。结论:咖啡因可通过抑制FAK/AKT/ROCK信号通路抑制U-373MG细胞的增殖、迁移和侵袭能力,并促进其凋亡。 展开更多
关键词 咖啡因 人脑胶质瘤 u-373MG细胞 增殖 迁移 侵袭 凋亡 FAK/AKT/ROCK通路
下载PDF
“U-S”协作,提升教师教科研能力
17
作者 宣亚泼 唐小燕 《教育视界》 2023年第10期48-50,共3页
为提升教师的教科研能力,江苏省常州市新北区新桥初级中学通过“U-S”协作模式,依托高校导师制,对不同发展阶段的教师进行差异化培养:启蒙新手阶段教师的教科研意识,培养适应阶段教师的教科研实践能力,提升成熟阶段教师的教科研素养。... 为提升教师的教科研能力,江苏省常州市新北区新桥初级中学通过“U-S”协作模式,依托高校导师制,对不同发展阶段的教师进行差异化培养:启蒙新手阶段教师的教科研意识,培养适应阶段教师的教科研实践能力,提升成熟阶段教师的教科研素养。学校创新教师培训方式,包括“引领+互动式”培训、“专题+主题式”培训、研训一体化培训、线上线下一体化培训等,激发教师投身教科研的热情,提高学校的教育教学质量。 展开更多
关键词 u-s”协作模式 高校导师制 教科研能力
下载PDF
民族地区英语师范生培养的U-S实践共同体构建研究——以广西民族师范学院为例
18
作者 韦冰霞 《广西民族师范学院学报》 2023年第1期99-106,共8页
新时代背景下,国家对师范生教学实践能力的提升、高校与中小学协同育人提出了更高的要求。在《普通高等学校本科专业类教学质量国家标准》《普通高等学校本科外国语言文学类专业教学指南》《普通高等学校师范类专业认证实施办法(暂行)... 新时代背景下,国家对师范生教学实践能力的提升、高校与中小学协同育人提出了更高的要求。在《普通高等学校本科专业类教学质量国家标准》《普通高等学校本科外国语言文学类专业教学指南》《普通高等学校师范类专业认证实施办法(暂行)》等纲领文件相继出台的背景下,基于简·莱夫和埃蒂纳·温格提出的“实践共同体”理论,文章以课题组所在的民族地区高校为例,针对英语师范生实践能力仍需进一步提高的现实,探索高校与中学共建U-S实践共同体的路径;提出U-S双方应构建共同事业,在课堂教学、实践教学、技能训练、学科竞赛、大学生创新创业项目与教研合作等方面营造相互协作的环境,同时建设共享技艺库,在现有的条件下最大化地实现资源共享,促进U-S双方共同提高,彰显高校服务地方的使命与担当。 展开更多
关键词 英语师范生 u-s实践共同体 民族地区
下载PDF
Sport Participation and Community Capacity Building in Disadvantaged Urban Communities
19
作者 Ivana Matteucci 《Sociology Study》 2023年第1期1-9,共9页
The aim of this study was to investigate the relationships between sport and community by examining the role played by sports participation in community engagement and community capacity building in disadvantaged urba... The aim of this study was to investigate the relationships between sport and community by examining the role played by sports participation in community engagement and community capacity building in disadvantaged urban communities.From a conceptual standpoint,the study is based on the sociological theory of the community and Community Capacity Building(CCB)theory,which provide overviews of the concept of community and community capacity and its characteristics.Four disadvantaged urban communities were investigated.Two of these communities had sports programs,while the other two did not.The online questionnaire methodology was adopted to assess the socio-demographic characteristics and community engagement of the participants(knowledge of programs and participation in community activities),and subsequently,an analysis of the online social media narratives of the community members themselves was developed to measure the characteristics of their community capacity building.We found that community engagement and community capacity values were higher in the communities with sports programs.These findings are promising and suggest that approaches based on sports participation development could be fruitful,particularly in disadvantaged communities. 展开更多
关键词 community engagement community capacity building SPORT disadvantaged community online narratives
下载PDF
Effects of Biostimulation-Bioaugmentation on Coastal Microbial Community in an in situ Mesocosm System
20
作者 YUAN Fangzheng ZHAO Yangyong +2 位作者 DAI Yulai YANG Wen ZHU Jinyong 《Journal of Ocean University of China》 CAS CSCD 2024年第1期233-246,共14页
Globally,various types of pollution affect coastal waters as a result of human activities.Bioaugmentation and biostimulation are effective methods for treating water pollution.However,few studies have explored the res... Globally,various types of pollution affect coastal waters as a result of human activities.Bioaugmentation and biostimulation are effective methods for treating water pollution.However,few studies have explored the response of coastal prokaryotic and eukaryotic communities to bioaugmentation and biostimulation.Here,a 28-day outdoor mesocosm experiment with two treatments(bioaugmentation-A and combined treatment of bioaugmentation and biostimulation-AS)and a control(untreated-C)were carried out.The experiment was conducted in Meishan Bay to explore the composition,dynamics,and co-occurrence patterns of prokaryotic and eukaryotic communities in response to the A and AS using 16S rRNA and 18S rRNA gene amplicon sequencing.After treatment,Gammaproteobacteria and Epsilonproteobacteria were significantly increased in group AS compared to group C,while Flavobacteriia and Saprospirae were significantly reduced.Dinoflagellata was significantly reduced in AS compared to C,while Chrysophyta was significantly reduced in both AS and A.Compared to C,the principal response curve analyses of the prokaryotic and eukaryotic communities both showed an increasing trend followed by a decreasing trend for AS.Furthermore,the trends of prokaryotic and eukaryotic communities in group A were similar to those in group AS compared with group C,but AS changed them more than A did.According to the species weight table on principal response curves,a significant increase was observed in beneficial bacteria in prokaryotic communities,such as Rhodobacterales and Oceanospirillales,along with a decrease in autotrophs in eukaryotic communities,such as Chrysophyta and Diatom.Topological properties of network analysis reveal that A and AS complicate the interactions between the prokaryotic and eukaryotic communities.Overall,these findings expand our understanding of the response pattern of the bioaugmentation and biostimulation on coastal prokaryotic and eukaryotic communities. 展开更多
关键词 prokaryotic community eukaryotic community BIOAUGMENTATION BIOSTIMULATION coastal waters
下载PDF
上一页 1 2 230 下一页 到第
使用帮助 返回顶部