The problem of molecular diffusion in the soup of chemical reactions attracts mounting interest across fields ranging from chemistry to biophysics to material science.Chemical reactions involve bond breakup and format...The problem of molecular diffusion in the soup of chemical reactions attracts mounting interest across fields ranging from chemistry to biophysics to material science.Chemical reactions involve bond breakup and formation,whose time scale is typically on the orders of fs to ps,while molecular diffusion occurs at time scales ofμs to ms.The two processes are often considered orthogonal,given the vastly different scales.The serial results show that the enzyme's diffusion is enhanced in a substrate-dependent manner,which was further extended to small molecule reaction systems,challenging this classical paradigm.However,the results from different groups using different techniques do not quantitatively agree,and a general mechanism is yet to be understood.We summarize experimental studies on diffusion problems and seek to reconcile the interpretation with understanding the limits of measurement tools and the chemical nature of reaction systems.Understanding molecular diffusion in chemical reactions will provide fresh thoughts in designing chemical systems such as molecular machines that harvest work at the nanoscale in a controllable manner.展开更多
A class of multi dimensional degenerate diffusion processes X ε(t) in R r(r≥2) are considered and the asymptotic properties of empirical measures are investigated; here X ε(t) saitisfies the stochastic differen...A class of multi dimensional degenerate diffusion processes X ε(t) in R r(r≥2) are considered and the asymptotic properties of empirical measures are investigated; here X ε(t) saitisfies the stochastic differential equation dX ε(t)=σ(X ε(t)) d W(t)+B(X ε(t)) d t+ εσ～(X ε(t)) d W(t),ε>0. X ε(t) are small random perturbations of the degenerate diffusion process X(t), which satisfies the stochastic differential equation dX(t)=σ(X(t)) d W(t)+B(X(t)) d t. A large deviation theorem for projection measures ν on R r-n (n<r) of empirical measures μ are proved展开更多
A combined computational and experimental investigation to examine temperature and soot volume fraction in coflow ethylene-air diffusion flames was presented.A numerical simulation was conducted by using a relatively ...A combined computational and experimental investigation to examine temperature and soot volume fraction in coflow ethylene-air diffusion flames was presented.A numerical simulation was conducted by using a relatively detailed gas-phase chemistry and complex thermal and transport properties coupled with a semi-empirical two-equation soot model.Thermal radiation was calculated using the discrete ordinates method.An image processing technique and a decoupled reconstruction method were used to simultaneously measure the distributions of temperature and soot volume fraction.The results show that the maximum error for temperature does not exceed 10% between the prediction and the measurement.And the maximum error is 6.9% for soot volume fraction between prediction and measurement.Additional simulations were performed to explore the effects of global equivalence ratio on diffusion flames and the soot formation.The results display that the soot formation increases with decreasing the coflow air velocity.And the soot formation in each case appears in the annular region,where the temperature ranges from about 1 000 K to 2 000 K and the profile becomes taller and wider when the coflow air is decreased.展开更多
Because of ground clutter wave interf e rence,it is difficult to measure smoke screen disturbance in the field.In this pape r,a kind of indoor measurement method of smoke screen disturbance efficiency ba sed on Gaussi...Because of ground clutter wave interf e rence,it is difficult to measure smoke screen disturbance in the field.In this pape r,a kind of indoor measurement method of smoke screen disturbance efficiency ba sed on Gaussian diffusion model is put forward.As a characteristic,the measur ement result of smoke screen area density proves that the indoor measurement met hod of smoke screen disturbance efficiency based on Gaussian diffusion model is fea sible.展开更多
Traumatic brain injury(TBI) is a major contributor of long-term disability and a leading cause of death worldwide. A series of secondary injury cascades can contribute to cell death, tissue loss, and ultimately to the...Traumatic brain injury(TBI) is a major contributor of long-term disability and a leading cause of death worldwide. A series of secondary injury cascades can contribute to cell death, tissue loss, and ultimately to the development of functional impairments. However, there are currently no effective therapeutic interventions that improve brain outcomes following TBI. As a result, a number of experimental TBI models have been developed to recapitulate TBI injury mechanisms and to test the efficacy of potential therapeutics. The pig model has recently come to the forefront as the pig brain is closer in size, structure, and composition to the human brain compared to traditional rodent models, making it an ideal large animal model to study TBI pathophysiology and functional outcomes. This review will focus on the shared characteristics between humans and pigs that make them ideal for modeling TBI and will review the three most common pig TBI models–the diffuse axonal injury, the controlled cortical impact, and the fluid percussion models. It will also review current advances in functional outcome assessment measures and other non-invasive, translational TBI detection and measurement tools like biomarker analysis and magnetic resonance imaging. The use of pigs as TBI models and the continued development and improvement of translational assessment modalities have made significant contributions to unraveling the complex cascade of TBI sequela and provide an important means to study potential clinically relevant therapeutic interventions.展开更多
The orifice-plate flowmeter and ultrasonic flowmeter are used widely for natural gas flowrate measurement, and the measurement accuracy is affected greatly by flow state. Numerical simulation was used to study the flo...The orifice-plate flowmeter and ultrasonic flowmeter are used widely for natural gas flowrate measurement, and the measurement accuracy is affected greatly by flow state. Numerical simulation was used to study the flow of natural gas in the diffusion pipe, and the length of the irregular flow induced by the diffuser or rectifier was computed. Simulation results indicated that the flow in the diffusion pipe was three-dimensional turbulent flow and the steady state flow was restored at 17 pipe-diameters downstream of the diffuser. The rectifiers equipped in the diffusion pipe showed good rectification effect, notwithstanding the induced irregular flow. Downstream the rectifier, the flow became symmetrical and uniform in a shorter length than the case without a rectifier. For the diffusion pipe equipped with plate rectifier, tube rectifier and tube-plate rectifier, the lengths at which uniformly distributed flow was restored were 12, 6 and 5 pipe-diameters downstream the rectifier respectively. On the basis of simulation results, the minimum installation length for flowmeters equipped in the diffusion pipe was determined. This provides a new method for improving natural gas measurement accuracy.展开更多
Data were collected from Three-north Region, Middle and upper reaches region of Yangtze River and Coastal region. By analysis of factors influencing soil erosion, the longitude, latitude, annual precipitation, and the...Data were collected from Three-north Region, Middle and upper reaches region of Yangtze River and Coastal region. By analysis of factors influencing soil erosion, the longitude, latitude, annual precipitation, and the slope degree were selected as regional independent variables and canopy density and stock litter were selected as independent variables, and integral diffusing models were established for evaluation of the benefit of soil and water conservation of forest. By solving the parameters of models using the package of STATISTICA, the Power function between independent variables and dependent variables was set up. The soil conservation amount of forest and economic values were estimated using the contrast method for the ecological forestry engineering of the above three areas.展开更多
Underwater reverberation environments that satisfy the conditions of uniformity and isotropy of the diffuse field can be used to measure the acoustic characteristics of underwater targets.This study combines two pract...Underwater reverberation environments that satisfy the conditions of uniformity and isotropy of the diffuse field can be used to measure the acoustic characteristics of underwater targets.This study combines two practical indicators—the standard deviation of the absolute sound pressure field(to indicate uniformity)and the analysis of the wavenumber spectrum in the spherical harmonics domain(to indicate isotropy)—for an accurate evaluation of the diffusion of the sound field in a reverberation tank.A method is proposed that can improve the narrow-band diffusion of the sound field by employing a randomly fluctuating surface.An acoustic experiment was performed in a reverberation water tank(1.2 m×1 m×0.8 m),where a randomly fluctuating surface was generated by making waves.The experimental results show that as the wave motion contributes effectively to the random reflection of sound rays in all directions,the uniformity and isotropy are improved significantly when the surface is fluctuating randomly.This work helps to ensure accurate measurements of the characteristics of underwater targets in reverberation tanks.展开更多
When a mass spreads in a turbulent flow, areas with obviously high concentration of the mass compared with surrounding areas are formed by organized structures of turbulence. In this study, we extract the high concent...When a mass spreads in a turbulent flow, areas with obviously high concentration of the mass compared with surrounding areas are formed by organized structures of turbulence. In this study, we extract the high concentration areas and investigate their diffusion process. For this purpose, a combination of Planar Laser Induced Fluorescence (PLIF) and Particle Image Velocimetry (PIV) techniques was employed to obtain simultaneously the two fields of the concentration of injected dye and of the velocity in a water turbulent channel flow. With focusing on a quasi-homogeneous turbulence in the channel central region, a series of PLIF and PIV images were acquired at several different downstream positions. We applied a conditional sampling technique to the PLIF images to extract the high concentration areas, or spikes, and calculated the conditional-averaged statistics of the extracted areas such as length scale, mean concentration, and turbulent diffusion coefficient. We found that the averaged length scale was constant with downstream distance from the diffusion source and was smaller than integral scale of the turbulent eddies. The spanwise distribution of the mean concentration was basically Gaussian, and the spanwise width of the spikes increased linearly with downstream distance from the diffusion source. Moreover, the turbulent diffusion coefficient was found to increase in proportion to the spanwise distance from the source. These results reveal aspects different from those of regular mass diffusion and let us conclude that the diffusion process of the spikes differs from that of regular mass diffusion.展开更多
Soil radon measurement of high stability and sensitivity is widely applied,and in some applications,such as in uranium prospecting,^(222)Rn should be distinguished from ^(220)Rn.To meet this requirement,a practical me...Soil radon measurement of high stability and sensitivity is widely applied,and in some applications,such as in uranium prospecting,^(222)Rn should be distinguished from ^(220)Rn.To meet this requirement,a practical method based on soil radon diffusion and accumulation theory to measure soil radon by Alpha Particle Spectroscopy(α-PS)is discussed in this paper.Theα-PS measurement method can effectively overcome the effects of ^(220)Rn and its daughters (^(216)Po,^(212)Bi,^(212)Po).The system can eliminate the impact of soil radon field disturbance and non-uniformity through soil radon static diffusion.Radon daughters(^(218)Po,^(214)Po)are accumulated under the action of an electrostatic force, which not only enhances the measurement sensitivity,but also increases robustness of the measurement.Simultaneous measurement of multiple points can increase the comparability of measurement data and the measurement efficiency. Experimental data shows that the soil radon measurement method was robust.So it has wide applications such as in geological prospecting,in fissure groundwater exploration and in ground subsidence inspection.展开更多
基金the National Natural Science Foundation of China through funding 22250610198 and 22174006.
文摘The problem of molecular diffusion in the soup of chemical reactions attracts mounting interest across fields ranging from chemistry to biophysics to material science.Chemical reactions involve bond breakup and formation,whose time scale is typically on the orders of fs to ps,while molecular diffusion occurs at time scales ofμs to ms.The two processes are often considered orthogonal,given the vastly different scales.The serial results show that the enzyme's diffusion is enhanced in a substrate-dependent manner,which was further extended to small molecule reaction systems,challenging this classical paradigm.However,the results from different groups using different techniques do not quantitatively agree,and a general mechanism is yet to be understood.We summarize experimental studies on diffusion problems and seek to reconcile the interpretation with understanding the limits of measurement tools and the chemical nature of reaction systems.Understanding molecular diffusion in chemical reactions will provide fresh thoughts in designing chemical systems such as molecular machines that harvest work at the nanoscale in a controllable manner.
文摘A class of multi dimensional degenerate diffusion processes X ε(t) in R r(r≥2) are considered and the asymptotic properties of empirical measures are investigated; here X ε(t) saitisfies the stochastic differential equation dX ε(t)=σ(X ε(t)) d W(t)+B(X ε(t)) d t+ εσ～(X ε(t)) d W(t),ε>0. X ε(t) are small random perturbations of the degenerate diffusion process X(t), which satisfies the stochastic differential equation dX(t)=σ(X(t)) d W(t)+B(X(t)) d t. A large deviation theorem for projection measures ν on R r-n (n<r) of empirical measures μ are proved
基金Projects(50806024,50806023 and 50806026) supported by the National Natural Science Foundation of China
文摘A combined computational and experimental investigation to examine temperature and soot volume fraction in coflow ethylene-air diffusion flames was presented.A numerical simulation was conducted by using a relatively detailed gas-phase chemistry and complex thermal and transport properties coupled with a semi-empirical two-equation soot model.Thermal radiation was calculated using the discrete ordinates method.An image processing technique and a decoupled reconstruction method were used to simultaneously measure the distributions of temperature and soot volume fraction.The results show that the maximum error for temperature does not exceed 10% between the prediction and the measurement.And the maximum error is 6.9% for soot volume fraction between prediction and measurement.Additional simulations were performed to explore the effects of global equivalence ratio on diffusion flames and the soot formation.The results display that the soot formation increases with decreasing the coflow air velocity.And the soot formation in each case appears in the annular region,where the temperature ranges from about 1 000 K to 2 000 K and the profile becomes taller and wider when the coflow air is decreased.
文摘Because of ground clutter wave interf e rence,it is difficult to measure smoke screen disturbance in the field.In this pape r,a kind of indoor measurement method of smoke screen disturbance efficiency ba sed on Gaussian diffusion model is put forward.As a characteristic,the measur ement result of smoke screen area density proves that the indoor measurement met hod of smoke screen disturbance efficiency based on Gaussian diffusion model is fea sible.
文摘Traumatic brain injury(TBI) is a major contributor of long-term disability and a leading cause of death worldwide. A series of secondary injury cascades can contribute to cell death, tissue loss, and ultimately to the development of functional impairments. However, there are currently no effective therapeutic interventions that improve brain outcomes following TBI. As a result, a number of experimental TBI models have been developed to recapitulate TBI injury mechanisms and to test the efficacy of potential therapeutics. The pig model has recently come to the forefront as the pig brain is closer in size, structure, and composition to the human brain compared to traditional rodent models, making it an ideal large animal model to study TBI pathophysiology and functional outcomes. This review will focus on the shared characteristics between humans and pigs that make them ideal for modeling TBI and will review the three most common pig TBI models–the diffuse axonal injury, the controlled cortical impact, and the fluid percussion models. It will also review current advances in functional outcome assessment measures and other non-invasive, translational TBI detection and measurement tools like biomarker analysis and magnetic resonance imaging. The use of pigs as TBI models and the continued development and improvement of translational assessment modalities have made significant contributions to unraveling the complex cascade of TBI sequela and provide an important means to study potential clinically relevant therapeutic interventions.
文摘The orifice-plate flowmeter and ultrasonic flowmeter are used widely for natural gas flowrate measurement, and the measurement accuracy is affected greatly by flow state. Numerical simulation was used to study the flow of natural gas in the diffusion pipe, and the length of the irregular flow induced by the diffuser or rectifier was computed. Simulation results indicated that the flow in the diffusion pipe was three-dimensional turbulent flow and the steady state flow was restored at 17 pipe-diameters downstream of the diffuser. The rectifiers equipped in the diffusion pipe showed good rectification effect, notwithstanding the induced irregular flow. Downstream the rectifier, the flow became symmetrical and uniform in a shorter length than the case without a rectifier. For the diffusion pipe equipped with plate rectifier, tube rectifier and tube-plate rectifier, the lengths at which uniformly distributed flow was restored were 12, 6 and 5 pipe-diameters downstream the rectifier respectively. On the basis of simulation results, the minimum installation length for flowmeters equipped in the diffusion pipe was determined. This provides a new method for improving natural gas measurement accuracy.
文摘Data were collected from Three-north Region, Middle and upper reaches region of Yangtze River and Coastal region. By analysis of factors influencing soil erosion, the longitude, latitude, annual precipitation, and the slope degree were selected as regional independent variables and canopy density and stock litter were selected as independent variables, and integral diffusing models were established for evaluation of the benefit of soil and water conservation of forest. By solving the parameters of models using the package of STATISTICA, the Power function between independent variables and dependent variables was set up. The soil conservation amount of forest and economic values were estimated using the contrast method for the ecological forestry engineering of the above three areas.
基金supported by the National Natural Science Foundation of China(Grant No.11874131)。
文摘Underwater reverberation environments that satisfy the conditions of uniformity and isotropy of the diffuse field can be used to measure the acoustic characteristics of underwater targets.This study combines two practical indicators—the standard deviation of the absolute sound pressure field(to indicate uniformity)and the analysis of the wavenumber spectrum in the spherical harmonics domain(to indicate isotropy)—for an accurate evaluation of the diffusion of the sound field in a reverberation tank.A method is proposed that can improve the narrow-band diffusion of the sound field by employing a randomly fluctuating surface.An acoustic experiment was performed in a reverberation water tank(1.2 m×1 m×0.8 m),where a randomly fluctuating surface was generated by making waves.The experimental results show that as the wave motion contributes effectively to the random reflection of sound rays in all directions,the uniformity and isotropy are improved significantly when the surface is fluctuating randomly.This work helps to ensure accurate measurements of the characteristics of underwater targets in reverberation tanks.
文摘When a mass spreads in a turbulent flow, areas with obviously high concentration of the mass compared with surrounding areas are formed by organized structures of turbulence. In this study, we extract the high concentration areas and investigate their diffusion process. For this purpose, a combination of Planar Laser Induced Fluorescence (PLIF) and Particle Image Velocimetry (PIV) techniques was employed to obtain simultaneously the two fields of the concentration of injected dye and of the velocity in a water turbulent channel flow. With focusing on a quasi-homogeneous turbulence in the channel central region, a series of PLIF and PIV images were acquired at several different downstream positions. We applied a conditional sampling technique to the PLIF images to extract the high concentration areas, or spikes, and calculated the conditional-averaged statistics of the extracted areas such as length scale, mean concentration, and turbulent diffusion coefficient. We found that the averaged length scale was constant with downstream distance from the diffusion source and was smaller than integral scale of the turbulent eddies. The spanwise distribution of the mean concentration was basically Gaussian, and the spanwise width of the spikes increased linearly with downstream distance from the diffusion source. Moreover, the turbulent diffusion coefficient was found to increase in proportion to the spanwise distance from the source. These results reveal aspects different from those of regular mass diffusion and let us conclude that the diffusion process of the spikes differs from that of regular mass diffusion.
文摘Soil radon measurement of high stability and sensitivity is widely applied,and in some applications,such as in uranium prospecting,^(222)Rn should be distinguished from ^(220)Rn.To meet this requirement,a practical method based on soil radon diffusion and accumulation theory to measure soil radon by Alpha Particle Spectroscopy(α-PS)is discussed in this paper.Theα-PS measurement method can effectively overcome the effects of ^(220)Rn and its daughters (^(216)Po,^(212)Bi,^(212)Po).The system can eliminate the impact of soil radon field disturbance and non-uniformity through soil radon static diffusion.Radon daughters(^(218)Po,^(214)Po)are accumulated under the action of an electrostatic force, which not only enhances the measurement sensitivity,but also increases robustness of the measurement.Simultaneous measurement of multiple points can increase the comparability of measurement data and the measurement efficiency. Experimental data shows that the soil radon measurement method was robust.So it has wide applications such as in geological prospecting,in fissure groundwater exploration and in ground subsidence inspection.
