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Optimization of Fixture Number in Large Thin-Walled Parts Assembly Based on IPSO
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作者 Changhui Liu Jing Wang +3 位作者 Ying Zheng Ke Jin Jianbo Yu Jianfeng Liu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第2期213-227,共15页
There are lots of researches on fixture layout optimization for large thin-walled parts.Current researches focus on the positioning problem,i.e.,optimizing the positions of a constant number of fixtures.However,how to... There are lots of researches on fixture layout optimization for large thin-walled parts.Current researches focus on the positioning problem,i.e.,optimizing the positions of a constant number of fixtures.However,how to determine the number of fixtures is ignored.In most cases,the number of fixtures located on large thin-walled parts is determined based on engineering experience,which leads to huge fixture number and extra waste.Therefore,this paper constructs an optimization model to minimize the number of fixtures.The constraints are set in the optimization model to ensure that the part deformation is within the surface profile tolerance.In addition,the assembly gap between two parts is also controlled.To conduct the optimization,this paper develops an improved particle swarm optimization(IPSO)algorithm by integrating the shrinkage factor and adaptive inertia weight.In the algorithm,particles are encoded according to the fixture position.Each dimension of the particle is assigned to a sub-region by constraining the optional position range of each fixture to improve the optimization efficiency.Finally,a case study on ship curved panel assembly is provided to prove that our method can optimize the number of fixtures while meeting the assembly quality requirements.This research proposes a method to optimize the number of fixtures,which can reduce the number of fixtures and achieve deformation control at the same time. 展开更多
关键词 Assembly quality Large thin-walled parts Fixture layout PSO FEM
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Development of Fixture Layout Optimization for Thin-Walled Parts:A Review
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作者 Changhui Liu Jing Wang +3 位作者 Binghai Zhou Jianbo Yu Ying Zheng Jianfeng Liu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期15-39,共25页
An increasing number of researchers have researched fixture layout optimization for thin-walled part assembly during the past decades.However,few papers systematically review these researches.By analyzing existing lit... An increasing number of researchers have researched fixture layout optimization for thin-walled part assembly during the past decades.However,few papers systematically review these researches.By analyzing existing literature,this paper summarizes the process of fixture layout optimization and the methods applied.The process of optimization is made up of optimization objective setting,assembly variation/deformation modeling,and fixture layout optimization.This paper makes a review of the fixture layout for thin-walled parts according to these three steps.First,two different kinds of optimization objectives are introduced.Researchers usually consider in-plane variations or out-of-plane deformations when designing objectives.Then,modeling methods for assembly variation and deformation are divided into two categories:Mechanism-based and data-based methods.Several common methods are discussed respectively.After that,optimization algorithms are reviewed systematically.There are two kinds of optimization algorithms:Traditional nonlinear programming and heuristic algorithms.Finally,discussions on the current situation are provided.The research direction of fixture layout optimization in the future is discussed from three aspects:Objective setting,improving modeling accuracy and optimization algorithms.Also,a new research point for fixture layout optimization is discussed.This paper systematically reviews the research on fixture layout optimization for thin-walled parts,and provides a reference for future research in this field. 展开更多
关键词 thin-walled parts Assembly quality Fixture layout optimization Modeling methods Optimization algorithms
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Meter-Scale Thin-Walled Structure with Lattice Infill for Fuel Tank Supporting Component of Satellite:Multiscale Design and Experimental Verification
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作者 Xiaoyu Zhang Huizhong Zeng +6 位作者 Shaohui Zhang Yan Zhang Mi Xiao Liping Liu Hao Zhou Hongyou Chai Liang Gao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第1期201-220,共20页
Lightweight thin-walled structures with lattice infill are widely desired in satellite for their high stiffness-to-weight ratio and superior buckling strength resulting fromthe sandwich effect.Such structures can be f... Lightweight thin-walled structures with lattice infill are widely desired in satellite for their high stiffness-to-weight ratio and superior buckling strength resulting fromthe sandwich effect.Such structures can be fabricated bymetallic additive manufacturing technique,such as selective laser melting(SLM).However,the maximum dimensions of actual structures are usually in a sub-meter scale,which results in restrictions on their appliance in aerospace and other fields.In this work,a meter-scale thin-walled structure with lattice infill is designed for the fuel tank supporting component of the satellite by integrating a self-supporting lattice into the thickness optimization of the thin-wall.The designed structure is fabricated by SLM of AlSi10Mg and cold metal transfer welding technique.Quasi-static mechanical tests and vibration tests are both conducted to verify the mechanical strength of the designed large-scale lattice thin-walled structure.The experimental results indicate that themeter-scale thin-walled structure with lattice infill could meet the dimension and lightweight requirements of most spacecrafts. 展开更多
关键词 thin-walled structure lattice infill supporting component selective laser melting SATELLITE
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An electromagnetic semi-active dynamic vibration absorber for thin-walled workpiece vibration suppression in mirror milling
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作者 Jianghua KONG Bei DING +3 位作者 Wei WANG Zhixia WANG Juliang XIAO Hongyun QIU 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第8期1315-1334,共20页
As critical components of aircraft skins and rocket fuel storage tank shells,large thin-walled workpieces are susceptible to vibration and deformation during machining due to their weak local stiffness.To address thes... As critical components of aircraft skins and rocket fuel storage tank shells,large thin-walled workpieces are susceptible to vibration and deformation during machining due to their weak local stiffness.To address these challenges,we propose a novel tunable electromagnetic semi-active dynamic vibration absorber(ESADVA),which integrates with a magnetic suction follower to form a followed ESADVA(follow-ESADVA)for mirror milling.This system combines a tunable magnet oscillator with a follower,enabling real-time vibration absorption and condition feedback throughout the milling process.Additionally,the device supports self-sensing and frequency adjustment by providing feedback to a linear actuator,which alters the distance between magnets.This resolves the traditional issue of being unable to directly monitor vibration at the machining point due to space constraints and tool interference.The frequency shift characteristics and vibration absorption performance are comprehensively investigated.Theoretical and experimental results demonstrate that the prototyped follow-ESADVA achieves frequency synchronization with the milling tool,resulting in a vibration suppression rate of approximately 47.57%.Moreover,the roughness of the machined surface decreases by18.95%,significantly enhancing the surface quality.The results of this work pave the way for higher-quality machined surfaces and a more stable mirror milling process. 展开更多
关键词 semi-active dynamic vibration absorber(SADVA) mirror milling selfsensing vibration absorption tuning thin-walled workpiece
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Numerical Analysis of Cold-Formed Thin-Walled Steel Short Columns with Pitting Corrosion during Bridge Construction
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作者 Hongzhang Wang Jing Guo +3 位作者 Shanjun Yang Chaoheng Cheng Jing Chen Zhihao Chen 《Structural Durability & Health Monitoring》 EI 2024年第2期181-196,共16页
Pitting corrosion is harmful during bridge construction,which will lead to uneven roughness of steel surfaces and reduce the thickness of steel.Hence,the effect of pitting corrosion on the mechanical properties of col... Pitting corrosion is harmful during bridge construction,which will lead to uneven roughness of steel surfaces and reduce the thickness of steel.Hence,the effect of pitting corrosion on the mechanical properties of cold-formed thin-walled steel stub columns is studied,and the empirical formulas are established through regression fitting to predict the ultimate load of web and flange under pitting corrosion.In detail,the failure modes and load-displacement curves of specimens with different locations,area ratios,and depths are obtained through a large number of non-linear finite element analysis.As for the specimens with pitting corrosion on the web,all the specimens are subject to local buckling failure,and the failure mode will not change with pitting corrosion,but the failure location will change with pitting corrosion location;the size,location,and area ratio of pitting corrosion have little influence on the ultimate load of cold-formed thin-walled steel short columns,but the loss rate of pitting corrosion section area has a greater impact on the ultimate bearing capacity.As for the specimen with flange pitting corrosion,the location and area ratio of pitting corrosion have less influence on the ultimate load of cold-formed thin-walled steel short columns,and the section area loss rate has greater influence on the ultimate bearing capacity;the impact of web pitting corrosion on the ultimate load is greater than that of flange pitting corrosion under the same condition of pitting corrosion section area.The prediction formulas of limit load which are suitable for pitting corrosion of web and flange are established,which can provide a reference for performance evaluation of corroded cold-formed thin-walled steel. 展开更多
关键词 Pitting corrosion cold-formed thin-walled steel ultimate load prediction formula short columns
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Boundary Element Analysis forModeⅢCrack Problems of Thin-Walled Structures from Micro-to Nano-Scales 被引量:1
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作者 Bingrui Ju Wenzhen Qu Yan Gu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第9期2677-2690,共14页
This paper develops a new numerical framework for modeⅢcrack problems of thin-walled structures by integrating multiple advanced techniques in the boundary element literature.The details of special crack-tip elements... This paper develops a new numerical framework for modeⅢcrack problems of thin-walled structures by integrating multiple advanced techniques in the boundary element literature.The details of special crack-tip elements for displacement and stress are derived.An exponential transformation technique is introduced to accurately calculate the nearly singular integral,which is the key task of the boundary element simulation of thin-walled structures.Three numerical experiments with different types of cracks are provided to verify the performance of the present numerical framework.Numerical results demonstrate that the present scheme is valid for modeⅢcrack problems of thin-walled structures with the thickness-to-length ratio in the microscale,even nanoscale,regime. 展开更多
关键词 Boundary element nearly singular integral thin-walled structure mode III crack
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Role of exosomal circular RNAs as microRNA sponges and potential targeting for suppressing hepatocellular carcinoma growth and progression 被引量:2
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作者 Nikolaos Papadopoulos Eleni-Myrto Trifylli 《World Journal of Gastroenterology》 SCIE CAS 2024年第9期994-998,共5页
In this editorial,we comment on the article by Lyu et al published in the recent issue of the World Journal of Gastroenterology(2023;2219-2840).Hepatocellular carcinoma(HCC)is a frequently encountered and highly aggre... In this editorial,we comment on the article by Lyu et al published in the recent issue of the World Journal of Gastroenterology(2023;2219-2840).Hepatocellular carcinoma(HCC)is a frequently encountered and highly aggressive primary liver cancer,which remains the third-commonest cause of cancer-related death despite the current therapeutic modalities.There is urgency in developing novel thera-peutic approaches,such as by manipulating extracellular vesicles,which con-stitute a highly heterogeneous nanoparticle population that contains various cargoes.These cargoes have a pivotal role in cell-to-cell communication and can modify the functional level of the recipient cells via their uptake by other recipient cells.Exosomal non-coding RNAs have particular evolving significance in HCC,such as circular RNAs,which have been found differentially expressed in normal hepatic and HCC tissues.The aberrations in their expression levels have a key role in the HCC development and progression and the overall prognosis.In this editorial,we will shed light on the emerging role of exosomal circular RNAs in HCC development and progression,focusing on the oncogenic or potentially tumor suppressive effect of mesenchymal stem cells-derived exosomal non-coding RNAs. 展开更多
关键词 circular SPONGE PROGRESSION
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Geometric Accuracy and Energy Absorption Characteristics of 3D Printed Continuous Ramie Fiber Reinforced Thin-Walled Composite Structures
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作者 Kui Wang Hao Lin +5 位作者 Antoine Le Duigou Ruijun Cai Yangyu Huang Ping Cheng Honghao Zhang Yong Peng 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第6期147-158,共12页
The application of continuous natural fibers as reinforcement in composite thin-walled structures offers a feasible approach to achieve light weight and high strength while remaining environmentally friendly.In additi... The application of continuous natural fibers as reinforcement in composite thin-walled structures offers a feasible approach to achieve light weight and high strength while remaining environmentally friendly.In addition,additive manufacturing technology provides a favorable process foundation for its realization.In this study,the printability and energy absorption properties of 3D printed continuous fiber reinforced thin-walled structures with different configurations were investigated.The results suggested that a low printing speed and a proper layer thickness would mitigate the printing defects within the structures.The printing geometry accuracy of the structures could be further improved by rounding the sharp corners with appropriate radii.This study successfully fabricated structures with vari-ous configurations characterized by high geometric accuracy through printing parameters optimization and path smoothing.Moreover,the compressive property and energy absorption characteristics of the structures under quasi-static axial compression were evaluated and compared.It was found that all studied thin-walled structures exhibited progressive folding deformation patterns during compression.In particular,energy absorption process was achieved through the combined damage modes of plastic deformation,fiber pullout and delamination.Furthermore,the com-parison results showed that the hexagonal structure exhibited the best energy absorption performance.The study revealed the structure-mechanical property relationship of 3D printed continuous fiber reinforced composite thin-walled structures through the analysis of multiscale failure characteristics and load response,which is valuable for broadening their applications. 展开更多
关键词 Additive manufacturing Continuous fiber BIOCOMPOSITE thin-walled structure Geometric accuracy Energy absorption
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Experimental Study on Entropy Features in Machining Vibrations of A Thin-Walled Tubular Workpiece
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作者 Kaibo Lu Xin Wang +2 位作者 Xun Chen Xinyu Pang Fengshou Gu 《Journal of Dynamics, Monitoring and Diagnostics》 2023年第1期61-68,共8页
In machining processes,chatter vibrations are always regarded as one of the major limitations for production quality and efficiency.Accurate and timely monitoring of chatter is helpful to maintain stable machining ope... In machining processes,chatter vibrations are always regarded as one of the major limitations for production quality and efficiency.Accurate and timely monitoring of chatter is helpful to maintain stable machining operations.At present,most chatter monitoring methods are based on the energy level at specified chatter frequencies or frequency bands.However,the spectral features of chatter could change during machining operations due to complexity and time-varying dynamics of the physical machining process.The purpose of this paper is to investigate the time-varying chatter features in turning of thin-walled tubular workpieces from the perspective of entropy.The airborne acoustics was selected as the source of information for machining condition monitoring.First,corresponding to the distinguishing surface topographies relevant to machining conditions,the features of the sound signal emitted during turning of the thin-walled cylindrical workpieces were extracted using the spectral analysis and wavelet packet transform,respectively.It was shown that the dominant vibration frequency as well as the energy distribution could shift with the transition of the machining status.After that,two relative entropy indicators based on the spectrum and the wavelet packet energy were constructed to identify chattering events in turning of the thin-walled tubes.The experimental results demonstrate that the proposed indicators could accurately reflect the transition of machining conditions with high sensitivity and robustness in comparison with the traditional FFT-based methods.The achievement of this study lays the foundations of the online chatter monitoring and control technique for turning of the thin-walled tubular workpieces. 展开更多
关键词 MACHINING chatter relative entropy thin-walled work pieces
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Evaluation of Industrial IoT Service Providers with TOPSIS Based on Circular Intuitionistic Fuzzy Sets
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作者 Elif Çalo˘glu Büyükselçuk 《Computers, Materials & Continua》 SCIE EI 2024年第7期715-746,共32页
Industrial Internet of Things(IIoT)service providers have become increasingly important in the manufacturing industry due to their ability to gather and process vast amounts of data from connected devices,enabling man... Industrial Internet of Things(IIoT)service providers have become increasingly important in the manufacturing industry due to their ability to gather and process vast amounts of data from connected devices,enabling manufacturers to improve operational efficiency,reduce costs,and enhance product quality.These platforms provide manufacturers with real-time visibility into their production processes and supply chains,allowing them to optimize operations and make informed decisions.In addition,IIoT service providers can help manufacturers create new revenue streams through the development of innovative products and services and enable them to leverage the benefits of emerging technologies such as Artificial Intelligence(AI)and machine learning.Overall,the implementation of IIoT platforms in the manufacturing industry is crucial for companies seeking to remain competitive and meet the ever-increasing demands of customers in the digital age.In this study,the evaluation criteria to be considered in the selection of IIoT service provider in small andmedium-sized(SME)manufacturing enterprises will be determined and IIoT service providers alternatives will be evaluated using the technique for order preference by similarity to an ideal solution(TOPSIS)method based on circular intuitionistic fuzzy sets.Based on the assessments conducted in accordance with the literature review and expert consultations,a set of 8 selection criteria has been established.These criteria encompass industry expertise,customer support,flexibility and scalability,security,cost-effectiveness,reliability,data analytics,as well as compatibility and usability.Upon evaluating these criteria,it was observed that the security criterion holds the highest significance,succeeded by cost-effectiveness,data analytics,flexibility and scalability,reliability,and customer support criteria,in descending order of importance.Following the evaluation of seven distinct alternatives against these criteria,it was deduced that the A6 alternative,a German service provider,emerged as the most favorable option.The identical issue was addressed utilizing sensitivity analysis alongside various multi-criteria decision-making(MCDM)methods,and after comprehensive evaluation,the outcomes were assessed.Spearman’s correlation coefficient was computed to ascertain the association between the rankings derived from solving the problem using diverse MCDM methods. 展开更多
关键词 IIoT MANUFACTURING TOPSIS circular intuitionistic fuzzy sets
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On the spreading behavior of a droplet on a circular cylinder using the lattice Boltzmann method
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作者 杨帆 金虎 戴梦瑶 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第6期434-443,共10页
The study of a droplet spreading on a circular cylinder under gravity was carried out using the pseudo-potential lattice Boltzmann high-density ratios multiphase model with a non-ideal Peng–Robinson equation of state... The study of a droplet spreading on a circular cylinder under gravity was carried out using the pseudo-potential lattice Boltzmann high-density ratios multiphase model with a non-ideal Peng–Robinson equation of state. The calculation results indicate that the motion of the droplet on the cylinder can be divided into three stages: spreading, sliding, and aggregating.The contact length and contact time of a droplet on a cylindrical surface can be affected by factors such as the wettability gradient of the cylindrical wall, the Bond number, and droplet size. Furthermore, phase diagrams showing the relationship between Bond number, cylinder wall wettability gradient, and contact time as well as maximum contact length for three different droplet sizes are given. A theoretical foundation for additional research into the heat and mass transfer process between the droplet and the cylinder can be established by comprehending the variable rules of maximum contact length and contact time. 展开更多
关键词 lattice Boltzmann methods DROPLET circular cylinder wettability gradient
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Optical storage of circular airy beam in atomic vapor
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作者 常虹 杨欣 +5 位作者 马燕 杨鑫琪 曹明涛 张晓斐 董瑞芳 张首刚 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第8期263-269,共7页
The realization of quantum storage of spatial light field is of great significance to the construction of high-dimensional quantum repeater.In this paper,we experimentally realize the storage and retrieval of circular... The realization of quantum storage of spatial light field is of great significance to the construction of high-dimensional quantum repeater.In this paper,we experimentally realize the storage and retrieval of circular Airy beams(CABs)by using theΛ-type three-level energy system based on the electromagnetically induced transparency in a hot rubidium atomic vapor cell.The weak probe beam field is modulated with phase distribution of CABs by a spatial light modulator.We store the probe circular Airy beam(CAB)into the rubidium atomic vapor cell and retrieve it after the demanded delay.We quantitatively analyze the storage results and give corresponding theoretical explanations.Moreover,we investigate the autofocusing and self-healing effect of the retrieved CAB,which indicates that the properties and beam shape of CAB maintain well after storage.Our work will have potential applications in the storage of high-dimensional quantum information,and is also useful for improving the channel capacities of quantum internet. 展开更多
关键词 circular Airy beam optical storage autofocusing effect self-healing effect
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Low-Complexity Reconstruction of Covariance Matrix in Hybrid Uniform Circular Array
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作者 Fu Zihao Liu Yinsheng Duan Hongtao 《China Communications》 SCIE CSCD 2024年第3期66-74,共9页
Spatial covariance matrix(SCM) is essential in many multi-antenna systems such as massive multiple-input multiple-output(MIMO). For multi-antenna systems operating at millimeter-wave bands, hybrid analog-digital struc... Spatial covariance matrix(SCM) is essential in many multi-antenna systems such as massive multiple-input multiple-output(MIMO). For multi-antenna systems operating at millimeter-wave bands, hybrid analog-digital structure has been widely adopted to reduce the cost of radio frequency chains.In this situation, signals received at the antennas are unavailable to the digital receiver, and as a consequence, traditional sample average approach cannot be used for SCM reconstruction in hybrid multi-antenna systems. To address this issue, beam sweeping algorithm(BSA) which can reconstruct the SCM effectively for a hybrid uniform linear array, has been proposed in our previous works. However, direct extension of BSA to a hybrid uniform circular array(UCA)will result in a huge computational burden. To this end, a low-complexity approach is proposed in this paper. By exploiting the symmetry features of SCM for the UCA, the number of unknowns can be reduced significantly and thus the complexity of reconstruction can be saved accordingly. Furthermore, an insightful analysis is also presented in this paper, showing that the reduction of the number of unknowns can also improve the accuracy of the reconstructed SCM. Simulation results are also shown to demonstrate the proposed approach. 展开更多
关键词 hybrid array MILLIMETER-WAVE spatial covariance matrix uniform circular array
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Temperature-Induced Unfolding Pathway of Staphylococcal Enterotoxin B:Insights from Circular Dichroism and Molecular Dynamics Simulation
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作者 LIU Ji ZHANG Shiyu +1 位作者 ZENG Yu DENG Yi 《食品科学》 EI CAS CSCD 北大核心 2024年第18期55-76,共22页
In this study,circular dichroism(CD)and molecular dynamics(MD)simulation were used to investigate the thermal unfolding pathway of staphylococcal enterotoxin B(SEB)at temperatures of 298–371 and 298–500 K,and the re... In this study,circular dichroism(CD)and molecular dynamics(MD)simulation were used to investigate the thermal unfolding pathway of staphylococcal enterotoxin B(SEB)at temperatures of 298–371 and 298–500 K,and the relationship between the experimental and simulation results were explored.Our computational findings on the secondary structure of SEB showed that at room temperature,the CD spectroscopic results were highly consistent with the MD results.Moreover,under heating conditions,the changing trends of helix,sheet and random coil obtained by CD spectral fitting were highly consistent with those obtained by MD.In order to gain a deeper understanding of the thermal stability mechanism of SEB,the MD trajectories were analyzed in terms of root mean square deviation(RMSD),secondary structure assignment(SSA),radius of gyration(R_(g)),free energy surfaces(FES),solvent-accessible surface area(SASA),hydrogen bonds and salt bridges.The results showed that at low heating temperature,domain Ⅰ without loops(omitting the mobile loop region)mainly relied on hydrophobic interaction to maintain its thermal stability,whereas the thermal stability of domain Ⅱ was mainly controlled by salt bridges and hydrogen bonds.Under high heating temperature conditions,the hydrophobic interactions in domain Ⅰ without loops were destroyed and the secondary structure was almost completely lost,while domain Ⅱ could still rely on salt bridges as molecular staples to barely maintain the stability of the secondary structure.These results help us to understand the thermodynamic and kinetic mechanisms that maintain the thermal stability of SEB at the molecular level,and provide a direction for establishing safer and more effective food sterilization processes. 展开更多
关键词 staphylococcal enterotoxin B circular dichroism molecular dynamics simulations temperature-induced unfolding
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Knockdown of circular RNA (CircRNA)_001896 inhibits cervical cancer proliferation and stemness in vivo and in vitro
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作者 JIA SHAO CAN ZHANG +2 位作者 YAONAN TANG AIQIN HE WEIPEI ZHU 《BIOCELL》 SCIE 2024年第4期571-580,共10页
Objective:Previous studies indicated that aberrant circular RNA(circRNA)expression affects gene expression regulatory networks,leading to the aberrant activation of tumor pathways and promoting tumor cell growth.Howev... Objective:Previous studies indicated that aberrant circular RNA(circRNA)expression affects gene expression regulatory networks,leading to the aberrant activation of tumor pathways and promoting tumor cell growth.However,the expression,clinical significance,and effects on cell propagation,invasion,and dissemination of circRNA_001896 in cervical cancer(CC)tissues remain unclear.Methods:The Gene Expression Omnibus(GEO)datasets(GSE113696 and GSE102686)were used to examine differential circRNA expression in CC and adjacent tissues.The expression of circRNA_001896 was detected in 72 CC patients usingfluorescence quantitative PCR.Correlation analysis with clinical pathological features was performed through COX multivariate and univariate analysis.The effect of circRNA_001896 downregulation on CC cell propagation was examined using the cell counting kit-8(CCK-8)test,clonogenic,3D sphere formation,and in vivo tumorigenesis assays.Results:Intersection of the GSE113696 and GSE102686 datasets revealed an increased expression of four circRNAs,including circRNA_001896,in CC tissues.Fluorescence quantitative PCR confirmed circRNA_001896 as a circular RNA.High expression of circRNA_001896 was considerably associated with lymph node metastasis,International Federation of Gynecologists and Obstetricians(FIGO)stage,tumor diameter,and survival period in CC patients.Proportional hazards model(COX)univariate and multivariate analyses revealed that circRNA_001896 expressions are a distinct risk factor affecting CC patients’prognosis.Cellular functional experiments showed that downregulating circRNA_001896 substantially suppressed CC cell growth,colony formation,and 3D sphere-forming ability.In vivo,tumorigenesis analysis in nude mice demonstrated that downregulating circRNA_001896 remarkably reduced the in vivo proliferation capacity of CC cells.Conclusion:CircRNA_001896 is highly expressed in CC tissues and is substantially related to lymph node metastasis,FIGO stage,tumor size,and survival period in patients.Moreover,downregulating circRNA_001896 significantly inhibits both in vivo and in vitro propagation of CC cells.Therefore,circRNA_001896 might be used as a biomarker for targeted therapy in cervical cancer. 展开更多
关键词 Uterine cervical neoplasms RNA circular Cell proliferation Cancer stem cells
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A novel efficient energy absorber with free inversion of a metal foam-filled circular tube
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作者 Jianxun ZHANG Jinwen BAI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第1期1-14,共14页
In this paper, a novel efficient energy absorber with free inversion of a metal foam-filled circular tube(MFFCT) is designed, and the axial compressive behavior of the MFFCT under free inversion is studied analyticall... In this paper, a novel efficient energy absorber with free inversion of a metal foam-filled circular tube(MFFCT) is designed, and the axial compressive behavior of the MFFCT under free inversion is studied analytically and numerically. The theoretical analysis reveals that the energy is mainly dissipated through the radial bending of the metal circular tube, the circumferential expansion of the metal circular tube, and the metal filled-foam compression. The principle of energy conservation is used to derive the theoretical formula for the minimum compressive force of the MFFCT over free inversion under axial loading. Furthermore, the free inversion deformation characteristics of the MFFCT are analyzed numerically. The theoretical steady values are found to be in good agreement with the results of the finite element(FE) analysis. The effects of the average diameter of the metal tube, the wall thickness of the metal tube, and the filled-foam strength on the free inversion deformation of the MFFCT are considered. It is observed that in the steady deformation stage, the load-carrying and energy-absorbing capacities of the MFFCT increase with the increase in the average diameter of the metal tube, the wall thickness of the metal tube, or the filled-foam strength. The specific energy absorption(SEA) of free inversion of the MFFCT is significantly higher than that of the metal tube alone. 展开更多
关键词 metal foam-filled circular tube(MFFCT) free inversion load-carrying capacity energy absorption
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Temperature effects on the failure of deep circular tunnel under true-triaxial compression
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作者 HUANG Lin-qi LIU Mao-lin +4 位作者 WANG Zhao-wei GUO Yi-de SI Xue-feng LI Xi-bing LI Chao 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第9期3119-3141,共23页
The failure characteristics of thermal treated surrounding rocks should be studied to evaluate the stability and safety of deep ground engineering under high-ground-temperature and high-ground-stress conditions.The fa... The failure characteristics of thermal treated surrounding rocks should be studied to evaluate the stability and safety of deep ground engineering under high-ground-temperature and high-ground-stress conditions.The failure process of the inner walls of fine-grained granite specimens at different temperatures(25–600℃)was analyzed using a true-triaxial test system.The failure process,peak intensity,overall morphology(characteristics after failure),rock fragment characteristics,and acoustic emission(AE)characteristics were analyzed.The results showed that for the aforementioned type of granite specimens,the trend of the failure stress conditions changed with respect to the critical temperature(200℃).When the temperature was less than 200℃,the initial failure stress increased,final failure stress increased,and failure severity decreased.When the temperature exceeded 200℃,the initial failure stress decreased,final failure stress decreased,and failure severity increased.When the temperature was 600℃,the initial and final failure stresses of the specimens decreased by 60.93%and 19.77%compared with those at 200℃,respectively.The numerical results obtained with the software RFPA3D-Thermal were used to analyze the effect of temperature on the specimen and reveal the mechanism of the failure process in the deep tunnel surrounding rock. 展开更多
关键词 deep ground rock failure GRANITE thermal treatment true-triaxial test circular tunnel RFPA3D-Thermal
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Development and Application of Ultrafast Circular Dichroism Spectroscopy Techniques
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作者 Tong Cui Menghui Jia +5 位作者 Peicong Wu Ke Hu Xueli Wang Sanjun Zhang Haifeng Pan Jinquan Chen 《Chinese Journal of Chemical Physics》 SCIE EI CAS CSCD 2024年第4期449-460,I0093,共13页
Chirality hold broad applications in life sciences,quantum devices,and various other areas.Traditionally,molecular chirality can be characterized by using steady-state circular dichroism spectroscopy.However,the techn... Chirality hold broad applications in life sciences,quantum devices,and various other areas.Traditionally,molecular chirality can be characterized by using steady-state circular dichroism spectroscopy.However,the techniques that can characterize excited state chirality are progressively capturing the public interest as it can provide the dynamic information for chirality generation and transfer.In this review,we focus on the theoretical background and the developmental history of femtosecond time-resolved circular dichroism spectroscopy(TRCD)techniques around the world.Additionally,we provide examples to showcase the utility of these techniques in the analysis of the dynamical molecular chemical structures,the investigation of molecular chirality generation,and the detection of electron spin dynamics in semiconductor quantum dots. 展开更多
关键词 Excited state chirality Femtosecond time-resolved circular dichroism spectroscopy Ultrafast dynamics Chiral spectra
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Impact of surface-reflected seismic waves on the seismic isolation performance of circular tunnel isolation layers
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作者 LU Jiahui LUO Junjie +3 位作者 HUANG Xiangyun HONG Junliang HE YanXin ZHOU Fulin 《Journal of Mountain Science》 SCIE CSCD 2024年第3期901-917,共17页
Seismic isolation is an effective strategy to mitigate the risk of seismic damage in tunnels.However,the impact of surface-reflected seismic waves on the effectiveness of tunnel isolation layers remains under explored... Seismic isolation is an effective strategy to mitigate the risk of seismic damage in tunnels.However,the impact of surface-reflected seismic waves on the effectiveness of tunnel isolation layers remains under explored.In this study,we employ the wave function expansion method to provide analytical solutions for the dynamic responses of linings in an elastic half-space and an infinite elastic space.By comparing the results of the two models,we investigate the seismic isolation effect of tunnel isolation layers induced by reflected seismic waves.Our findings reveal significant differences in the dynamic responses of the lining in the elastic half-space and the infinitely elastic space.Specifically,the dynamic stress concentration factor(DSCF)of the lining in the elastic half-space exhibits periodic fluctuations,influenced by the incident wave frequency and tunnel depth,while the DSCF in the infinitely elastic space remain stable.Overall,the seismic isolation application of the tunnel isolation layer is found to be less affected by surface-reflected seismic waves.Our results provide valuable insights for the design and assessment of the seismic isolation effect of tunnel isolation layers. 展开更多
关键词 circular tunnel seismic isolation Surface reflection Response of liners Wave-function expansion method
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Compressive properties of glue-laminated timber circular post modified by basalt fiber reinforced polymer
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作者 WEI Peixing GUO Wenzhen +2 位作者 ZHAO Mingjing GUO Zhensheng WANG Jianhe 《林业工程学报》 CSCD 北大核心 2024年第5期67-74,共8页
Glued timber structure is one of the main forms of modern wood architecture,which has gradually developed towards mid-and high-rise buildings.Glue-laminated timber(GLT)is comprised of several laminates of parallel-to-... Glued timber structure is one of the main forms of modern wood architecture,which has gradually developed towards mid-and high-rise buildings.Glue-laminated timber(GLT)is comprised of several laminates of parallel-to-grain dimension lumber that are bonded together with durable,moisture resistant structural adhesives.GLT can be used in horizontal applications as a beam and in vertical applications as a post.So,its compressive performance has a significant impact on structural safety.Fiber reinforced polymers(FRPs)were commonly used to improve the bearing capacity of GLT components,and the structural and process parameters largely determined the reinforcement effect.This study was aimed at investigating the influence of structural and process parameters on the axial compression performance of GLT components.Three wrapping methods(middle-part,end-part and full wrapping)and three lengths(0.6,0.8,and 1.0 m)of wood post specimens were designed in this work and the axial compression performance and ductility of GLT post specimens modified by basalt fiber reinforced polymer(BFRP)were studied.The results showed that the effect of different BFRP wrapping methods on the compressive strength and elastic modulus of laminated wood was not statistically significant(P>0.05).The compressive bearing capacity of unreinforced GLT posts decreased with the increase of aspect ratio.The GLT posts with middle-part and end-part wrapping still followed this pattern,while the compressive bearing capacity of GLT posts with full wrapping showed a pattern of first decreasing and then increasing.For GLT with low aspect ratios(4.0 or 5.3),there was no correlation between the wrapping method and the compressive bearing capacity,while the compressive bearing capacity of GLT with a high aspect ratio(6.7)for middle-part,end-part and full wrapping increased by 3.5%,7.5%and 9.7%,respectively.Compared to the unreinforced group,the ultimate axial compressive strength and modulus of elasticity(MOE)of the 6-E series specimens reinforced at both ends decreased by 2.58%and 6.70%,respectively.The ultimate axial compressive strength of the 8-E specimens reinforced at both ends increased by 8.62%and the MOE decreased by 1.91%.The compressive strength of the 10-E specimens reinforced at both ends increased by 7.51%and the MOE increased by 8.14%.The failure modes of GLT with different aspects were consistent under the same BFRP wrapping,while the failure modes of GLT with the same aspect ratio were different for different BFRP wrapping methods.The ductility performance of GLT with different aspects ratio was improved by the BFRP wrapping. 展开更多
关键词 basalt fiber reinforced polymer(BFRP) GLT circular post bearing performance
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