Does the use of double hormone replacement therapy for trauma patient organ donors improve organ recovery for transplant

BACKGROUND With an ongoing demand for transplantable organs,optimization of donor management protocols,specifically in trauma populations,is important for obta-ining a high yield of viable organs per patient.Endocrine management of brain-dead potential organ donors(BPODs)is controversial,leading to heterogeneous clinical management approaches.Previous studies have shown that when levo-thyroxine was combined with other treatments,including steroids,vasopressin,and insulin,BPODs had better organ recovery and survival outcomes were increased for transplant recipients.AIM To determine if levothyroxine use in combination with steroids in BPODs increased the number of organs donated in trauma patients.METHODS A retrospective review of adult BPODs from a single level 1 trauma center over ten years was performed.Exclusion criteria included patients who were not solid organ donors,patients who were not declared brain dead(donation after circulatory death),and patients who did not receive steroids in their hospital course.Levothyroxine and steroid administration,the number of organs donated,the types of organs donated,and demographic information were recorded.Univariate analyses were performed with P<0.05 considered to be statistically significant.RESULTS A total of 88 patients met inclusion criteria,69(78%)of whom received levothyroxine and steroids(ST/LT group)vs 19(22%)receiving steroids without levothyroxine(ST group).No differences were observed between the groups for gender,race,pertinent injury factors,age,or other hormone therapies used(P>0.05).In the ST/LT group,68.1%(n=47)donated a high yield(3-5)of organ types per donor compared to 42.1%(n=8)in the ST group(P=0.038).There was no difference in the total number of organ types donated between the groups(P=0.068).CONCLUSION This study suggests that combining levothyroxine and steroid administration increases high-yield organ donation per donor in BPODs in the trauma patient population.Limitations to this study include the retrospective design and the relatively small number of organ donors who met inclusion criteria.This study is unique in that it mitigates steroid administration as a confounding variable and focuses specifically on the adjunctive use of levothyroxine.

Influence of Intensive Insulin Therapy on Vascular Endothelial Growth Factor in Patients with Severe Trauma

The influence of early-stage intensive insulin therapy on the plasma levels of vascular en- dothelial growth factor （VEGF） and the related parameters in patients with severe trauma and the clini- cal implication were investigated. Sixty-four cases of severe trauma （injury severity score 〉20） with stress hyperglycemia （blood glucose 〉9 mmol/L） were randomly divided into intensive insulin therapy group and conventional therapy group. ELISA method, radioimmunoassay and density gradient grada- tion one-step process were used to determine plasma VEGF, endothelin-1 （ET-1）, and the number of circulating endothelial cells （CECs） at the day of 0, 2, 3, 5 and 7 after admission. Simultaneously, the changes of CRP concentration in plasma were monitored to evaluate inflammatory response. The results showed that plasma levels of observational indexes in patients receiving early-stage intensive insulin therapy were all significantly lower than those in conventional therapy groups 2, 3, 5 and 7 days after admission [for VEGF （ng/L）, 122.2±23.8 vs. 135.9±26.5, 109.6±27.3 vs. 129.0±18.4, 88.7±18.2 vs. 102.6±27.3, 54.2±26.4 vs. 85.7±35.2, P〈0.05, 0.01, 0.05, 0.05 respectively; for ET-1 （ng/L）, 162.8±23.5 vs. 173.7±13.2, 128.6±17.5 vs. 148.8±22.4, 96.5±14.8 vs. 125.7±14.8, 90.7±16.9 vs. 104.9±22.5, P〈0.05, 0.01, 0.01, 0.01 respectively; for CRP （mg/L）, 23.2±13.8 vs. 31.9±16.5, 13.6±17.3 vs. 23.5±18.4, 8.7±10.2 vs. 15.6±13.3, 5.2±9.4 vs. 10.7±11.2, all P〈0.05; for CECs （/0.9 μL）, 10.9±5.6 vs. 13.9±6.2, 8.5±4.9 vs. 11.3±5.3, 6.3±6.4 vs. 9.4±5.7, 4.8±7.1 vs. 7.8±4.8, all P〈0.05]. It was concluded that intensive insulin therapy could antagonize the endothelium injury after trauma and reduce inflammation response quickly, which was one of important mechanisms by which intensive insulin therapy improves the prognosis of trauma patients.

Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury

Traumatic spinal cord injury is a devastating disorder chara cterized by sensory,motor,and autonomic dysfunction that seve rely compromises an individual's ability to perform activities of daily living.These adve rse outcomes are closely related to the complex mechanism of spinal cord injury,the limited regenerative capacity of central neurons,and the inhibitory environment fo rmed by traumatic injury.Disruption to the microcirculation is an important pathophysiological mechanism of spinal cord injury.A number of therapeutic agents have been shown to improve the injury environment,mitigate secondary damage,and/or promote regeneration and repair.Among them,the spinal cord microcirculation has become an important target for the treatment of spinal cord injury.Drug inte rventions targeting the microcirculation can improve the microenvironment and promote recovery following spinal cord injury.These drugs target the structure and function of the spinal cord microcirculation and are essential for maintaining the normal function of spinal neuro ns,axons,and glial cells.This review discusses the pathophysiological role of spinal cord microcirculation in spinal cord injury,including its structure and histopathological changes.Further,it summarizes the progress of drug therapies targeting the spinal cord mic rocirc ulation after spinal cord injury.

It's all about timing, early treatment with hyperbaric oxygen therapy and corticosteroids is essential in acute acoustic trauma

Background: Acute acoustic trauma (AAT) is an acute hearing impairment caused by intense noiseimpact. The current management strategy for AAT with substantial hearing loss in the Dutch militaryis the combination therapy with corticosteroids and hyperbaric oxygen therapy (HBOT). In a previousstudy, early initiation of the combination therapy was associated with better outcomes. Therefore, weperformed a new analysis to assess the difference in hearing outcome between patients in whomcombination therapy was started within two days, versus after more than two days.Methods: A retrospective analysis was performed on military patients diagnosed with AAT with substantial hearing loss who presented between February 2018 and March 2020. Absolute and relativehearing improvement between first and last audiograms were calculated for all affected frequencies(defined as loss of 20 dB on initial audiogram). We also determined the amount of patients whorecovered to the level of Dutch military requirement, and performed speech discrimination tests.Results: In this analysis, 30 male patients (49 ears) with AAT were included. The median age was 24.5years (IQR 23e29). The median time to initiation of therapy with corticosteroids and HBOT were one andtwo days, respectively. HBOT was started within two days in 31 ears, and after more than two days in 18ears. The mean absolute and relative hearing gains were 18.8 dB (SD 14.6) and 46.8% (SD 31.3) on allaffected frequencies. The 100% discrimination/speech perception level improved from 64.0 dB to 51.7 dB(gain 12.3 dB ± 14.1). There was significantly more improvement in absolute and relative hearingimprovement when HBOT was started in 2 days, compared to >2 days.Conclusion: Our analysis shows results in favor of early initiation ( 2 days) of the combination treatmentof HBOT and corticosteroids in patients with AAT.

Management of traumatic peripheral artery pseudoaneurysm:A 10-year experience at a single center

Purpose: This study aimed to report our 10-year experience with the management of iatrogenic(penetrating trauma) and traumatic(blunt or penetrating trauma) peripheral artery pseudoaneurysms, based on data from a tertiary referral center.Methods: From January 2012 to December 2021, the medical records of consecutive patients with iatrogenic and traumatic peripheral artery pseudoaneurysms were retrospectively reviewed. Patient demographics, clinical features, imaging data, treatment details, and follow-up results were analyzed.Results: Sixty-one consecutive patients were included in this study;48(79%) were men and 13(21%) women,with a mean age of 49.4 ± 13.4 years(range 24–73 years). There were 42 patients(69%) who underwent open surgery, 18(29%) undergoing endovascular embolization or stent implantation, and one(2%) undergoing ultrasound-guided thrombin injection. All patients successfully underwent open or interventional treatment. The median follow-up was 46.8 months(2.5–117.9 months), and the overall reintervention rate was 10%. Of these,one(5%) patient in the interventional treatment group and five(12%) patients in the open surgery group underwent reintervention. The overall complication rate was 8%, with complications occurring only in the open surgery group. No deaths occurred in the peri-operative period. No late complications, such as thrombosis or pseudoaneurysm recurrence, were observed.Conclusion: Peripheral artery pseudoaneurysms arising from iatrogenic or traumatic causes can be effectively treated by both open surgery and interventional procedures in selected patients with acceptable mid-and long-term outcomes.

Hypopituitary syndrome with pituitary crisis in a patient with traumatic shock:A case report

BACKGROUND Shock is among the most common conditions that clinicians face in intensive care unit(ICU),of which hypovolemic shock is encountered most frequently;some patients instead suffer from neurogenic,cardiogenic,or infectious forms of shock.However,there are additional types of shock from unusual causes that are often undiagnosed.Here,we report the case of a patient who was initially misdiagnosed with hypovolemic shock,but exhibited persistent hypotension because of continuous fluid replacement and vasoactive drug administration,and was eventually diagnosed with hypopituitarism with crisis.CASE SUMMARY A 73-year-old Chinese man was admitted to the neurosurgery department following injury caused by a heavy object with symptoms of anemia and high fever.He was transferred to the ICU on the fourth day after hospitalization because of hypotension and unconsciousness.Blood analysis indicated that the patient was suffering from anemia and thrombocytopenia.Ultrasonography showed that there was no apparent abnormality in the cardiac structure but there was mild tricuspid regurgitation.Computed tomography revealed that there were signs of hemorrhage at the right basal ganglia;accordingly,hypovolemic shock,possibly septic shock,was initially considered.Even after routine treatment for shock,the hypotension remained severe.The patient was again thoroughly examined to investigate the underlying cause.The antishock therapy was supplemented with corticosteroids to counter potential hypopituitarism.The patient made a full recovery,and the blood pressure returned to normal.CONCLUSION A case of pituitary adenoma with multiple injuries was identified.Because of hypopituitarism,functionality of the corresponding endocrine system was restricted,with the most pronounced manifestation being unstable blood circulation requiring hormone replacement therapy.Such cases are relatively rare but may occur if multiple injuries are sustained.The present case represents a reference for the clinical treatment of patients with multiple injuries.

The Power of Theater Expression and Communication:A Psychological Theraputical Intervention in a Refugee Camp:An IPA Study Into the Narratives of Women Refugees’Experience With Drama Therapy

Forced displacement poses a major global crisis that must be tackled at all levels:political,socio-economic,and psychological.This paper describes the psychological impact of forced displacement on women and explains the significance of drama therapy intervention(DTI)in treating and empowering trauma impacted refugee women.Frequently used to treat immigrant and refugee adolescents and children in many host communities,DTI is seldom applied to women refugees who suffer from psychological disorders compounded by fleeing their home country and by difficulties faced in host communities.This makes our study the first on women refugees leaving a zone of war and residing in dire conditions in refugee camps.To best analyze the impact of DTI,this study(1)utilizes a qualitative approach to explain the effects of drama therapy intervention on Syrian and Palestinian-Syrian refugee women in Lebanon;(2)It applies a modified five-phase DTI program to fit the experiment setting and conducts post-DTI interviews;(3)It uses interpretative phenomenological analysis(IPA)method to identify emergent themes and to analyze the effectiveness of DTI;(4)Finally,the study concludes that drama therapy can both help refugee women deal with war-related/post-migration emotional trauma and can implement positive changes and help its participants form social bonds among each other.

Wet cupping(Al-hijamah)as a strange cause of ear trauma:A case report

BACKGROUND Cupping therapy is used across the globe since ancient Egypt.It is used as a complementary or alternative to daily clinical practice.Cupping therapy could be dry or wet(Al-hijamah)type.It is considered a relatively safe procedure for a variety of clinical problems like lower backache,shoulder pain,neck pain,headache,and migraine.Application of cupping therapy over body orifices is contraindicated.CASE SUMMARY A 27-year-old gentleman presented with sudden left-sided hearing loss and tinnitus for 7 d.He gave a history of upper respiratory tract infection 14 d before his complaints.He received Al-hijamah over his left ear 3 d before seeking advice from the Otolaryngology clinic,but without benefit.Physical examination showed a dull-looking left ear drum,hemotympanum in the posterior part of the tympanic cavity,two blood clots over the eardrum,and multiple bleeding points over the external ear canal and tympanic membrane.A pure tone audiogram and tympanogram confirmed the diagnosis of middle ear effusion.Conservative treatment(avoidance of water entry,antibiotics,and local and systemic decongestants)was given for 5 d.The presenting symptoms as well as ear injuries resolved completely two weeks after the follow-up.CONCLUSION We do not recommend using Al-hijamah directly over the ear as a treatment option for hearing loss to avoid unwanted ear trauma as well as there is no benefit from this kind of treatment.

Thoraco-Lumbar Junction Disc Herniation and Tight Filum: A Unique Combination?

Purpose: The incidence of both symptomatic thoraco-lumbar junction disc herniation (TLJDH) and tight filum (TF) may be underestimated. Both conditions have a complex clinical presentation that may involve the distal spinal cord, conus medullaris, and/or cauda equina, including upper and/or lower motor neuron impairment, sensory impairment, urological and sexual dysfunction. The coexistence of both conditions has not been previously reported and may be a diagnostic and therapeutic challenge. Methods: We report three teenage girls, a 24-year-old woman, and two middle-aged women who were diagnosed with both conditions and treated at our institution. Results: Disc herniation level was T11-T12 in 2, T12-L1 in 3, and L1-L2 in one. All patients had a fatty filum (n = 5) and/or a low-lying CM (at or above L1-L2 in 2, at or below L2-L3 in 4), and were treated with filum sectioning first. All patients noted marked improvement of preoperative complaints including back pain (n = 5), leg pain and fatigue (n = 4), urological complaints (n = 4), and toe gait (n = 1). One 16-year-old girl successfully underwent a thoracoscopic microdiscectomy for persisting pain at the thoraco-lumbar junction two years after filum sectioning. Conclusions: Thoraco-lumbar junction disc herniation and tight filum both act on the distal spinal cord close to the transition to the cauda equina. Both conditions may coincide and may even act synergistically, the disc herniation acting as a fulcrum, aggravating the deleterious effect of the tethering force (and vice versa). This might explain why both conditions combined may present at a younger age. We suggest filum sectioning as the primary treatment option in all patients, however, more cases and a longer follow-up are needed to better understand their unique combination and interaction. Nevertheless, when confronted with a symptomatic TLJDH especially in young patients we advise to rule out a coinciding TF by careful consideration of all clinical, radiological, and urological data.

Right Post-Traumatic Diaphragmatic Hernia with Liver Dislocation

Diaphragmatic hernia is a rare consequence of thoraco-abdominal trauma. It may be associated with high morbidity and mortality, particularly if surgical intervention is delayed. We report a case of a right diaphragmatic hernia in a 75-year-old woman. The patient was referred to our hospital with mild dyspnea. Chest radiograph showed an overtly elevated right hemi-diaphragm. Thoracic and abdominal computed tomographic scan was requested and showed a defect of the right diaphragmatic muscle wall with intrathoracic ascension of the liver. During the postoperative course, the patient was still on mechanical ventilation, hemodynamically unstable. She developped urinary peritonitis and an extensive bowel ischemia worsening. We report this case to show that the prognosis is related to associated injuries and possible complications. The possibility of a diaphragmatic rupture should be kept in mind and surgery is mandatory in order to avoid complications.

活血化瘀法联合穴位按摩在重型颅脑外伤中的应用

目的探究活血化瘀法联合穴位按摩在重型颅脑外伤中的应用效果。方法选取2020年2月—2022年2月于赣州市人民医院就诊的重型颅脑外伤患者68例,采用随机数字表法分为观察组、参考组,各34例。两组均行改良标准大骨瓣开颅手术,术后参考组给予常规干预,观察组在其基础上给予活血化瘀法联合穴位按摩干预,对比两组治疗效果,治疗前后中医证候积分及内毒素(LPS)、肿瘤坏死因子-α(TNF-α)水平。结果观察组治疗总有效率为97.06%(33/34),高于参考组的82.35%(28/34)(P<0.05)。治疗后,观察组活动不利、意识恍惚、感觉异常、舌㖞语謇积分与LPS、TNF-α水平均低于参考组(P<0.05)。结论活血化瘀法联合穴位按摩治疗重型颅脑外伤临床效果确切,对改善患者临床症状并降低LPS、TNF-α水平具有重要意义。

创伤聚焦的认知行为疗法在童年家庭功能障碍儿童和青少年中的应用

童年家庭功能障碍(childhood household dysfunction,CHD)是一种常见的童年期不良经历,会对儿童和青少年造成严重的身心危害。创伤聚焦的认知行为疗法(trauma-focused cognitive behavioral therapy,TF-CBT)是帮助经历童年创伤的儿童和青少年处理创伤记忆的循证心理治疗,旨在提高CHD儿童和青少年的应对能力,从而改善其创伤所致的负面影响,有效减轻其心理负担。TF-CBT能有效改善CHD儿童和青少年的创伤后应激障碍、情绪和行为问题以及家庭功能。建议今后开展高质量的原始研究,制订基于潜在预测因素的有针对性的TF-CBT干预方案,采取线上和线下相结合的方式,构建适应中国CHD人群的TF-CBT干预模式,以满足CHD儿童和青少年的心理健康服务需求。

疗愈创伤:文学人类学视角下《谁惧死亡》的文学治疗解读

《谁惧死亡》是当代美籍非裔科幻小说作家尼迪·奥科拉弗的获奖力作。小说主要讲述一位具有治愈魔力的两族混血女孩给后末日时代的非洲大陆带来和平的奇幻故事。小说既再现了现实世界部落战争以及割礼文化给人类带来的创伤,又以文学虚构的手法对其进行治愈。从文学人类学视角探究《谁惧死亡》中文学治疗机制的构建,并阐述其文学治疗功能。作者奥科拉弗借用非洲本土文化在小说内构建了神圣治疗机制,并以此实现了作者—读者的双向治疗:作者通过创作小说对自我进行了疗愈,小说的意向读者通过阅读抚慰了残酷现实带给他们的创伤。

脑外伤患者治疗中应用高压氧疗法的临床效果研究

目的探究脑外伤患者治疗中应用高压氧疗法的临床效果。方法病例来源于2017年8月至2019年9月期间苏州市中西医结合医院神经外科收治的100例脑外伤患者,用随机数字表法分为观察组与对照组,各50例。对照组给予常规治疗,观察组在此基础上给予高压氧疗法治疗。对比两组临床疗效、昏迷程度与神经功能缺损程度。结果两组治疗前格拉斯哥昏迷指数(GCS)及美国卫生研究院卒中量表(NIHSS)评分对比,差异无统计学意义(P>0.05);观察组治疗后GCS高于对照组,NIHSS评分低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论高压氧疗法治疗脑外伤患者的效果显著,可改善患者神经功能缺损,减轻昏迷程度。

OJU Peyronie’s Disease in an Elderly Ghanaian Gentleman—A Case-Report and Literature Review

Background: Peyronie’s disease is characterized by fibrous plaque formation in the tunica albuginea, leading to penile curvature and sexual dysfunction. Surgical correction is often required in cases of severe deformity or significant functional impairment. Aim: To present the case of a patient with severe Peyronie’s disease who underwent surgical correction using an autologous fascia lata graft. Case Presentation: We report the case of a 77-year-old Black-African gentleman with Peyronie’s disease, presenting with a self-reported penile curvature of 70 degrees and significant sexual frustration. He was managed surgically with plaque excision followed by a tunica albuginea patch using a subcutaneously harvested autologous fascia lata graft, all performed in a single surgical session. Conclusion: This case highlights the importance of individualized surgical planning and patient-specific considerations in achieving optimal outcomes in the management of Peyronie’s disease, particularly in cases requiring grafting for severe curvature.

冲击波联合表面肌电生物反馈训练对创伤后肘关节僵硬的疗效

目的观察冲击波联合表面肌电生物反馈训练对创伤后肘关节僵硬的治疗效果。方法选取2021年1-12月在杭州市富阳中医骨伤医院康复科收治的创伤后肘关节僵硬患者80例,采用抽签法随机分配至对照组和治疗组,每组40例。对照组采用常规康复治疗(软组织松解、关节松动术、关节连续被动运动和冷疗),治疗组在常规康复治疗后采用冲击波疗法联合表面肌电生物反馈训练。两组患者每天训练1次,每周5 d,持续8周。比较两组患者治疗前后的视觉模拟疼痛评分(visual analogue scale,VAS)、肘关节主动活动度(active range of motion,AROM)、Mayo肘关节功能评分情况。结果经过8周治疗,两组患者的VAS疼痛评分、AROM、Mayo肘关节功能评分均较治疗前好转(P<0.001),治疗组在治疗后的VAS评分、AROM、Mayo肘关节功能评分改善值均优于对照组(P<0.05,P<0.001,P<0.001),两组患者治疗后均未出现不适症状。结论冲击波配合表面肌电生物反馈训练可以有效缓解创伤后肘关节僵硬患者的疼痛,改善肘关节的功能,并提高肘关节的主动关节活动度。

时效激励护理结合放松疗法在伴童年创伤的青少年抑郁症患者中的应用效果

目的探究时效激励护理结合放松疗法在伴童年创伤的青少年抑郁症患者中的应用效果。方法选取2021年6月至2022年12月本院收治的96例伴童年创伤的青少年抑郁症患者为研究对象,以随机数字表法将其分为单一组(48例,放松疗法)和联合组(48例,放松疗法+时效激励护理)。比较两组干预前、后的抑郁、失眠情况、心理弹性、幸福指数及生活质量。结果干预后,两组的抑郁自评量表(SDS)、汉密尔顿抑郁量表(HAMD)、阿森斯失眠量表(AIS)评分均明显低于干预前,且联合组低于单一组(P<0.05)。干预后,两组的力量、乐观、坚韧评分及总分均明显高于干预前,且联合组高于单一组(P<0.05)。干预后,两组的学习成长、幸福感、自我肯定评分均明显高于干预前,且联合组高于单一组(P<0.05)。干预后,两组的生活质量量表各维度评分均明显高于干预前,且联合组高于单一组(P<0.05)。结论时效激励护理结合放松疗法可减轻伴童年创伤青少年抑郁症患者的抑郁、失眠程度,增强心理弹性及幸福感,提高生活质量,促进患者尽快恢复正常生活。

接纳承诺疗法对颅内血肿清除术患者身心健康的影响

目的探讨接纳承诺疗法对颅脑外伤患者术后身心健康的影响。方法选取68例经颅内血肿清除术治疗的颅脑外伤患者,随机分为两组,每组34例。对照组采取常规护理干预,实验组在对照组基础上加用接纳承诺干预。采用汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评估患者焦虑抑郁程度,采用心理弹性量表(CD-RISC)评估心理弹性,采用简易应对方式量表(SCSQ)评价应对方式。采用简易精神状态检查量表(MMSE)评价认知功能。结果干预后,实验组HAMA、HAMD评分均低于对照组(P<0.05),CD-RISC各项评分均高于对照组(P<0.05),积极应对评分高于对照组(P<0.05),消极应对评分低于对照组(P<0.05),定向力、即刻记忆力、注意力和计算力、回忆能力、语言能力评分、总分均高于对照组(P<0.05)。结论接纳承诺疗法用于颅内血肿清除术患者中,可改善患者的焦虑抑郁状态和认知功能,有助于促进患者术后的身心健康恢复。

危重创伤患者输血治疗后血小板、纤维蛋白原与输血不良反应的相关性研究

目的探讨危重创伤患者输血治疗后血小板、纤维蛋白原与输血不良反应的关系。方法84例危重创伤患者均给予输血治疗,比较输血前后的血小板和纤维蛋白原水平,分析血小板、纤维蛋白原与不良反应的相关性。结果输血后24~72h,血小板、纤维蛋白原水平逐渐升高。输血后,发生组的血小板和纤维蛋白原水平均低于未发生组(P<0.05),血小板、纤维蛋白原与不良反应的发生均呈负相关(r<0,P<0.05)。结论危重创伤患者输血治疗后血小板、纤维蛋白原与不良反应发生风险密切相关。

通窍活血汤对颅脑外伤手术患者的治疗效果研究

目的探究通窍活血汤对颅脑外伤手术患者的治疗效果。方法选取2022年1月—2023年1月于徐州市贾汪区人民医院进行手术治疗的78例颅脑外伤患者,根据随机数表法分成针刺组与中药组,每组39例。所有患者均接受手术治疗与术后康复训练(包括常规肢体功能与认知功能训练),在此基础上,针刺组接受针刺治疗,中药组接受通窍活血汤治疗。比较两组治疗总有效率、神经功能、运动功能、日常生活能力改善情况。结果中药组的治疗总有效率(92.31%)明显高于针刺组(71.79%),差异有统计学意义(χ^(2)=5.571,P<0.05)。经治疗,中药组神经功能评分低于针刺组,肢体运动功能及日常生活能力评分均高于针刺组,差异有统计学意义(P均<0.05)。结论颅脑外伤手术患者术后采用通窍活血汤治疗,疗效显著,可改善其神经功能、运动功能,加强其日常生活自理能力。