A Preliminary Clinical Study of Three Dimensional Ultrasonography in Prenatal Diagnosis

To evaluate the clinical value of three dimensional ultrasonography (3DUS) in prenatal diagnosis, 134 pregnant women with high risk factors in second and third trimester were examined by 3DUS. The results showed that 3DUS could provide more diagnostic information, exclude the abnormalities and enhance the confidence level of physician in 102 normal pregnant women. 3DUS was helpful in the diagnosis in 17 (60.7 %) of 28 cases of fetal anomalies. However, 3DUS was not useful in evaluating intrauterine growth retardation in 4 cases. It is conclucded that 3DUS is helpful in prenatal diagnosis.

Earth Pressure of the Trapdoor Problem Using Three-Dimensional Discrete Element Method

Load transformation from the yielding part of the soil to the adjacent part is known as the soil arching effect,which plays an important role in the design of various geotechnical infrastructures.Terzaghi’s trapdoor test was an importantmilestone in the development of theories on soil arching.The research on earth pressure of the trapdoor problem is presented in this paper using the three-dimensional(3D)discrete element method(DEM).Five 3D trapdoor models with different heights are established by 3DDEMsoftware PFC 3D.The variation of earth pressure on the trapdoor with the downward movement of the trapdoor,the distribution of vertical earth pressure along the horizontal direction,the distribution of vertical earth pressure along the vertical direction,the distribution of lateral earth pressure coefficient along the depth direction,the magnitude and direction of contact force chain are studied,respectively.Related research results show that the earth pressure on the trapdoor decreases rapidly after the downward movement of the trapdoor,and then reaches the minimum earth pressure.After that,the earth’s pressure will rise slightly,and whether this phenomenon occurs depends on the depth ratio.For the bottom soil,due to the stress transfer caused by the soil arching effect,the ratio of earth pressure in the loose area decreases,while the ratio of earth pressure in the stable area increases.With the trapdoor moving down,the vertical earth pressure along the depth in the stable zone is basically consistent with the initial state,which shows an approximate linear distribution.After the trapdoor moves down,the distribution of earth pressure along with the depth in the loose area changes,which is far less than the theoretical value of vertical earth pressure of its self-weight.Because of the compression of the soil on both sides,the lateral earth pressure coefficient of most areas on the central axis of the loose zone is close to the passive earth pressure coefficient Kp.The existence of a‘soil arch’can be observed intuitively from the distribution diagram of the contact force chain in the loose zone.

THUDosePD:a three-dimensional Monte Carlo platform for phantom dose assessment

Monte Carlo simulations are frequently utilized in radiation dose assessments.However,many researchers find the prevailing computing platforms to be intricate.This highlights a pressing need for a specialized framework for phantom dose evalua-tion.To address this gap,we developed a user-friendly radiation dose assessment platform using the Monte Carlo toolkit,Geant4.The Tsinghua University Phantom Dose(THUDosePD)augments the flexibility of Monte Carlo simulations in dosi-metric research.Originating from THUDose,a code with generic,functional,and application layers,THUDosePD focuses predominantly on anatomical phantom dose assessment.Additionally,it enables medical exposure simulation,intricate geometry creation,and supports both three-dimensional radiation dose analysis and phantom format transformations.The system operates on a multi-threaded parallel CPU architecture,with some modules enhanced for GPU parallel computing.Benchmark tests on the ICRP reference male illustrated the capabilities of THUDosePD in phantom dose assessment,covering the effective dose,three-dimensional dose distribution,and three-dimensional organ dose.We also conducted a voxelization conversion on the polygon mesh phantom,demonstrating the method’s efficiency and consistency.Extended applications based on THUDosePD further underline its broad adaptability.This intuitive,three-dimensional platform stands out as a valuable tool for phantom radiation dosimetry research.

A modified OMP method for multi-orbit three dimensional ISAR imaging of the space target

The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)algorithm.Firstly,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction dimension.Then,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix data.Finally,scattering centers can be reconstructed with specific three dimensional locations.Numerical simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.

Spectroscopic Studies of a Three-dimensional, Five-coordinated Copper(Ⅱ) Complex via Hydrogen Bonds: [Cu(PDA)(H_2O)_2](H_2PDA=Pyridine-2,6-dicarboxylic Acid)

A new copper(Ⅱ) complex [Cu(PDA)(H 2O) 2] was synthesized and its structure was determined. Cu(Ⅱ) is five coordinated in a tetragonal pyramid geometry. The two coordinating water molecules are different and the two Cu-O bond lengths differ by nearly 0.02 nm. The whole crystal is linked to form a three dimensional network by means of hydrogen bonds. The X band ESR spectrum shows three different g tensors with a well resolved hyperfine structure in the g z signal, giving the ESR parameters g x=2 05, g y =2 065 and g z =2 29. The covalency of the coordinate bonds and the deviation from tetragonal pyramid geometry for the complex are discussed based on the ESR spectra.

Three-Dimensional Ultrasonography in Obstetrics:the Clinical Value

To investigate the clinical value of three dimensional ultrasonography (3DUS) in obstetrics, various 3DUS rendering methods including surface mode, transparent mode and multiplanar mode were employed to scan 30 fetuses in second and third trimester by using the transabdominal volume transducer. The results showed that surface mode could vividly demonstrate the surface morphologic features of the fetuses, as well as the stereo shape and the spatial relationship among the surface structures. The face, limbs, umbilical cord and outer genitalia of the fetus could be well displayed by surface mode. Transparent mode could reveal the bony structures under the surface, such as ribs, vertebrae, crania, etc. The result was not affected by the sophisticated curvature of these bony structures and the success rate was up to 100 %. When rendered by multiplanar mode, the region of interest (ROI) could be viewed from different directions. It should be concluded that 3DUS could serve as a supplement to two dimensional ultrasonography (2DUS). 3DUS might play an important role in prenatal diagnosis and enhance the diagnostic confidence level of the physicians.

Characteristics of the ThreeDimensional Fluorescence Spectra of Fossil Fuels

We have found some fluorescence characteristics of fossil fuels based on the contour maps of the three dimensional fluorescence spectra of their non quenching samples. The common fluorescence characteristic is that the main peaks of various fossil fuels are located in the vicinity of excitation/emission wavelength pair 228nm/340nm.The diversity of fluorescence characteristics can be represented with several indexes α,K,F and R ,and these indexes provide measurable parameters for division of fluorescence fingerprints of fossil fuels. The fluorescence fingerprints of fossil fuels can be divided into five models named O,B,Q,P and G that are corresponding to condensate oil, light oil, heavy oil, coal and natural gas, respectively. The technique has a potential application in study of environment pollution on crude oil and geochemical exploration of fossil fuels.

Review of Electronic Speckle Pattern Interferometry(ESPI) for Three Dimensional Displacement Measurement

Three dimensional（3D） displacements, which can be translated further into 3D strain, are key parameters tor design, manufacturing and quality control. Using different optical setups, phase-shift methods, and algorithms, several different 3D electronic speckle pattern interferometry（ESPl） systems for displacement and strain measurements have been achieved and commercialized. This paper provides a review of the recent developments in ESPI systems for 3D displacement and strain measurement. After an overview of the fundamentals of ESP! theory, temporal phase-shift, and spatial phase-shift techniques, 3D deformation measurements by the temporal phase-shift ESPI system, which is suited well for static measurement, and by the spatial phase-shift ESPI system, which is particularly useful for dynamic measurement, are discussed. For each method, the basic theory, a brief derivation and different optical layouts are presented. The state of art application, potential and limitation of the ESPI systems are shown and demonstrated.

THREE DIMENSIONAL NONLINEAR NUMERICAL MODEL WITH INCLINED PRESSURE FOR SALTWATER INTRUSION AT THE YANGTZE RIVER ESTUARY

A three-dimensional nonlinear numerical model with inclined pressure was developed to compute the saltwater intrusion at the Yangtze River Estuary. The σ-transformation was introduced in the vertical plane to achieve the same lattices in the whole domain of interest. The mode-splitting technique can be used to split the three-dimensional governing equations into the surface gravity waves (external mode) and the internal gravity waves (internal mode). And the external mode was solved by the improved double-sweep-implicit (DSI) finite difference method and the internal mode was solved by the Eulerian-Lagrangian method. The Eulerian-Lagrangian method can not only reduce the numerical diffusion but also increase the computational accuracy through the improvement of the finite difference scheme in the vertical direction. The application of the model to the Yangtze River Estuary was carried out for the calculation of the saltwater intrusion and the null point. Results of the temporal and spatial distribution of the flow velocity and the salinity coincide with the measured data quite well. The formation and location of the underwater sandbars in the North Channel of the Yangtze River Estuary are closely related to the local salinity, the null point, the predominant current and the residual flow.

Accuracy of three-dimensional seismic ground response analysis in time domain using nonlinear numerical simulations

To provide appropriate uses of nonlinear ground response analysis for engineering practice, a three-dimensional soil column with a distributed mass system and a time domain numerical analysis were implemented on the Open Sees simulation platform. The standard mesh of a three-dimensional soil column was suggested to be satisfied with the specified maximum frequency. The layered soil column was divided into multiple sub-soils with a different viscous damping matrix according to the shear velocities as the soil properties were significantly different. It was necessary to use a combination of other one-dimensional or three-dimensional nonlinear seismic ground analysis programs to confirm the applicability of nonlinear seismic ground motion response analysis procedures in soft soil or for strong earthquakes. The accuracy of the three-dimensional soil column finite element method was verified by dynamic centrifuge model testing under different peak accelerations of the earthquake. As a result, nonlinear seismic ground motion response analysis procedures were improved in this study. The accuracy and efficiency of the three-dimensional seismic ground response analysis can be adapted to the requirements of engineering practice.

THREE-DIMENSIONAL CHARACTERISTICS AND HOMOGENIZATION OF ELECTROMAGNETIC FIELD IN SOFT-CONTACT CONTINUOUS CASTING MOLD

The three-dimensional electromagnetic characteristics and non-uniform distribution of electromagnetic field in soft-contact continuous casting mold have been analyzed by numerical simulation. The results show that the maximum electromagnetic flux density is found in front of slit; the electromagnetic flux density becomes large as the coil current and slit number increase. In a certain frequency range, the electromagnetic flux density increases with the increase of frequency and the frequency range is different with the change of azimuthal position along the inner wall of mold. The uniformity of electromagnetic field is influenced mainly by frequency and mold structure parameters. Increasing slit number and adjusting slit arrangement position can improve the electromagnetic flux density and the uniformity of electromagnetic field. For a soft-contact mold with 16 slits, when frequency is 20 kHz, the optimal slit arrangement parameter is a:b=1:2, c=0.

Three dimensional tectonic stress field in North China

According to the latest data of geological structure, geophysics, in-situ stress measurement and focal mechanism,3-D tectonic stress field model in North China is built and 3-D tectonic stress field pattern of North China aresimulated by finite element method. Then the overall characteristics and regional specific feature of North Chinaare studied. Finally, the influences of the valid dynamic boundary conditions of North China Block, active faultsand the inhomogeneity of crustal medium on tectonic stress field of North China are investigated.

NUMERICAL METHOD OF MIXED FINITE VOLUME-MODIFIED UPWIND FRACTIONAL STEP DIFFERENCE FOR THREE-DIMENSIONAL SEMICONDUCTOR DEVICE TRANSIENT BEHAVIOR PROBLEMS

Transient behavior of three-dimensional semiconductor device with heat conduc- tion is described by a coupled mathematical system of four quasi-linear partial differential equations with initial-boundary value conditions. The electric potential is defined by an ellip- tic equation and it appears in the following three equations via the electric field intensity. The electron concentration and the hole concentration are determined by convection-dominated diffusion equations and the temperature is interpreted by a heat conduction equation. A mixed finite volume element approximation, keeping physical conservation law, is used to get numerical values of the electric potential and the accuracy is improved one order. Two con- centrations and the heat conduction are computed by a fractional step method combined with second-order upwind differences. This method can overcome numerical oscillation, dispersion and decreases computational complexity. Then a three-dimensional problem is solved by computing three successive one-dimensional problems where the method of speedup is used and the computational work is greatly shortened. An optimal second-order error estimate in L2 norm is derived by using prior estimate theory and other special techniques of partial differential equations. This type of mass-conservative parallel method is important and is most valuable in numerical analysis and application of semiconductor device.

Analysis of three-dimensional vortexes below the free surface in a continuous casting mold

To study fluctuations of the free surface of liquid steel in the mold,two different models with the same casting conditions but different thicknesses were employed to analyze the hydrodynamic behavior at the top of the mold.The first model was a standard thickness slab,and the second had a thickness three times wider.It is found with the second model that above the plane formed by the steel jets,it is possible to observe four three-dimensional vortexes that interact with the submerged entry nozzle（SEN）and mold walls.By using a biphasic model to simulate the interface between the liquid and air inside the mold,the flow asymmetry and the fluctuations of the free surface can be clearly observed.

Fabrication and abrasive wear properties of metal matrix composites reinforced with three-dimensional network structure

Reticulated polyurethane was chosen as the preceramic material for preparing the porous preform using the replication process. The immersing and sintering processes were each performed twice for fabricating a high-porosity and super-strong skeleton. The aluminum magnesium matrix composites reinforced with three-dimensional network structure were prepared using the infiltration technique by pressure assisting and vacuum driving. Light interfacial reactions have played a profitable role in most of the ceramic-metal systems. The metal matrix composites interpenetrated with the ceramic phase have a higher wear resistance than the metal matrix phase. The volume fraction of ceramic reinforcement has a significant effect on the abrasive wear, and the wear rate can be decreased with the increase of the volume fraction of reinforcement.

Three-dimensional graphitic carbon sphere foams as sorbents for cleaning oil spills

Frequent offshore oil spill accidents, industrial oily sewage, and the indiscriminate disposal of urban oily sewage have caused seri- ous impacts on the human living environment and health. The traditional oil-water separation methods not only cause easily environmental secondary pollution but also a waste of limited resources. Therefore, in this work, three-dimensional (3D) graphitic carbon sphere (GCS) foams (collectively referred hereafter as 3D foams) with a 3D porous structure, pore size distribution of 25-200 μm, and high porosity of 62vol% were prepared for oil adsorption via gel casting using GCS as the starting materials. The results indicate that the water contact angle (WCA) of the as-prepared 3D foams is 130°. The contents of GCS greatly influenced the hydrophobicity, WCA, and microstructure of the as-prepared samples. The adsorption capacities of the as-prepared 3D foams for paraffin oil, vegetable oil, and vacuum pump oil were approximately 12-15 g/g, which were 10 times that of GCS powder. The as-prepared foams are desirable characteristics of a good sorbent and could be widely used in oil spill accidents.

Quasi-real time inversion method of three-dimensional epicenter coordinate, trigger time, and magnitude based on CORS

This study explores the quasi-real time inversion principle and precision estimation of three-dimensional coordinates of the epicenter, trigger time and magnitude of earthquakes with the aim to improve traditional methods, which are flawed due to missing information or distortion in the seismograph records. The epicenter, trigger time and magnitude from the Lushan earthquake are inverted and analyzed based on high-frequency GNSS data. The inversion results achieved a high precision, which are consistent with the data published by the China Earthquake Administration. Moreover, it has been proven that the inversion method has good theoretical value and excellent application prospects.

Modeling and validating three dimensional human normal cervix and cervical cancer tissues in vitro

The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies.The aim of this study was to engineer a functional 3-D in vitro model of normal and cancerous cervical tissue.Normal epithelial and immortalized cervical epithelial carcinoma cell lines were used to construct 3-D artificial normal cervical and cervical cancerous tissues.De-epidermised dermis（DED） was used as a scaffold for both models.Morphological analyses were conducted by using hematoxylin and eosin staining and characteristics of the models were studied by analyzing the expression of different structural cytokeratins and differential protein marker MAX dimerisation protein 1（Mad1） using immunohistochemical technique.Haematoxylin and eosin staining results showed that normal cervical tissue had multi epithelial layers while cancerous cervical tissue showed dysplastic changes.Immunohistochemistry staining revealed that for normal cervix model cytokeratin 10 was expressed in the upper stratified layer of the epithelium while cytokeratin 5 was expressed mainly in the middle and basal layer.Cytokeratin 19 was weakly expressed in a few basal cells.Cervical cancer model showed cytokeratin 19 expression in different epithelial layers and weak or no expression for cytokeratin 5 and cytokeratin 10.Madl expression was detected in some suprabasal cells.The 3-D in vitro models showed stratified epithelial layers and expressed the same types and patterns of differentiation marker proteins as seen in corresponding in vivo tissue in either normal cervical or cervical cancerous tissue.These findings imply that they can serve as functional normal and cervical cancer models.

Measurement and Analysis of Three-Dimensional Surface Topography of Sawn Timber Based on Scanning Probe Method

In order to explore the characteristics of the three-dimensional surface morphology of sawn timber,a three-dimensional wood surface morphology tester based on the scanning probe method and the principle of atomic force microscope was used to test the three-dimensional sur face morphology of three kinds of sawn timber and calculate its surface roughness.This study also analyzed the reasonable plan for the value of wood surface roughness and the advantages of the three dimensional shape tester,as well as the influence of tree species,three sections,air dry density and other factors on the surface roughness of the specimen after mechanical processing.The results have shown that it is a more appropriate method to select the calculated values of S。and Sq as the evaluation of the surface roughness of wood with random surface characteristics.The three dimensional wood surface topo-graphy tester can efficiently,conveniently and accurately display the three dimensional topography of wood at a micron-level resolution,and is characterized by high eficiency and good durability.The three dimensional surface morphology characteristics of the three sawn woods correspond to their roughness.The surface roughness of woods is arranged as follows:Sitka spruce>Larch>Beech.For the same tree species,the roughness of the corresponding section after sawing is as follows:chordwise section>crosswise section>radial section.The radial section has lower roughness than the other surfaces.The surface roughness of the wood after sawing is mainly related to its air-dry density.The above is intended to provide a useful reference for the application of measuring and evaluating the surface roughness of sawn timber using the three dimensional surface topography test method.

Use of three dimensional-printing in the management of floating aortic thrombus due to occult aortic dissection:A case report

BACKGROUND Floating thrombus within the thoracic aorta is a rare entity but may cause systemic embolism.The pathogenesis of floating aortic thrombi is not yet fully understood.No definitive guidelines are available for the management of floating aortic thrombus.CASE SUMMARY We report a 48-year-old patient,without a history of trauma and infection,who presented with sudden severe back pain.A floating thrombus within the aortic arch was found by computed tomography angiography(CTA).No evidence of coagulopathies was found.However,with the assistance of a three dimensionalprinted model,this floating thrombus was identified to be caused by occult aortic dissection(AD).Subsequently,an emergency thoracic endovascular repair was performed.The patient’s back pain was rapidly alleviated postoperatively.CTA at 1 year showed no filling defect in the stent-graft and aorta.CONCLUSION Occult AD is a potential factor causing floating aortic thrombi,endovascular stent-graft exclusion may be an optimal therapeutic choice with promising results.Moreover,the combination of CTA and three dimensional-printed models can contribute to the diagnosis and treatment of floating aortic thrombi due to occult AD.