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The Study of English Teaching Methods in Secondary Vocational School Based on the Role Letter's Therapy
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作者 吕政凤 《海外英语》 2013年第20期27-28,共2页
Secondary vocational school students is different from ordinary high school students and university students,especially in the aspect of English teaching and learning.In view of the special career orientation of secon... Secondary vocational school students is different from ordinary high school students and university students,especially in the aspect of English teaching and learning.In view of the special career orientation of secondary vocational school education.English teaching methods in secondary vocational schools should have more practical and targeted. Used the Role Letter's Therapy in English teaching can help students develop interest in learning English and learning initiative consciousness. In this paper I will talk about the important of the Role Letter's Therapy in English teaching of Secondary vocational school,and how to use it. 展开更多
关键词 ENGLISH TEACHING methods ROLE Letter’ therapy self
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Which treatment protocol, among classical methods and/or various laser applications is the most effective in root canal disinfection, <i>in vitro</i>? A systematic review
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作者 Joanna Theodosopoulou Konstantinos Chochlidakis Alexandra Tsigarida 《Open Journal of Stomatology》 2011年第4期126-139,共14页
Purpose: The aim of this systematic review was to answer the question “Which treatment protocol, am- ong classical methods and/or various laser applica- tions is the most effective in root canal disinfection, in vitr... Purpose: The aim of this systematic review was to answer the question “Which treatment protocol, am- ong classical methods and/or various laser applica- tions is the most effective in root canal disinfection, in vitro”. Materials and Methods: A MEDLINE, a Co- chrane and an Embase search (three specified search- es) were conducted to identify randomized controlled trials (RCT) until June 2010, conducted on human teeth and published in English, German or French language, examining the root canal disinfection after the use of lasers with or without mechanical instru-mentation. Additionally, hand search was conducted and contact with authors, when needed. Results: The MEDLINE, the Cochrane and the EMBASE search identified 240, 28, and 35 published articles, respec-tively. Ten articles from the MEDLINE and 5 articles from the Cochrane search (that were also identified in the MEDLINE search) met the inclusion and va-lidity assessment criteria. In E. faecalis elimination, instrumentation of the root canal and diode laser/665 nanometer/1 Watt (diode laser/665 nm/1 W) irradia-tion with the combined effect of Methylene Blue (MB) as photosensitizing agent (logCFU/ml = 1636) seemed to be the best method. In P. aeruginosa and in A.naeslundii elimination, instrumentation of the root canal followed by irrigation with 5, 25% NaOCl (log-CFU/ml = 0) seemed to be the best method. In gen-eral, instrumentation of the root canal followed by irrigation with 5, 25% NaOCl (logCFU/ml = 0) and instrumentation of the root canal and Er: YAG laser/ 2940 nm/0.8 W irradiation (logCFU/ml = 1924) seemed to be the best (polymicrobial studies). Conclusions: There are treatment protocols with the assistance or not of laser irradiation that can eliminate E. faecalis, E. coli and S. aureus inside the root canal. However, there is a serious number of S. anginosus, F. nuclea-tum, A. naeslundii and P. aeruginosa that remain in-side the root canal even after laser irradiation. New research is needed in order to set a treatment proto-col effective in the root canal disinfection from all bac-teria that are related to endodontic origin pathology. 展开更多
关键词 Lasers CLASSICAL methods ENDODONTIC Root Canal therapy DENTIN Bacteria Disinfection
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Discussion on prevention and control of COVID-19 by non-drug methods in traditional Chinese medicine
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作者 Bin-Hong Yan Fan Yang +5 位作者 Qian Niu Kai Li Zhi-Chao Jin Mi Li Kun Niu Yi-Qiang Xie 《Journal of Hainan Medical University》 2020年第18期9-13,共5页
COVID-19 has been discovered since December 2019 and has become a global pandemic recently,killing hundreds of thousands of people in 216 countries and regions around the world.COVID-19 has caused more than 4000 death... COVID-19 has been discovered since December 2019 and has become a global pandemic recently,killing hundreds of thousands of people in 216 countries and regions around the world.COVID-19 has caused more than 4000 deaths in China,seriously affecting national health and national economy.Since the outbreak of COVID-19,National Health Commission of the People's Republic of China has used the method of sino-western medicine to prevent and control COVID-19,effectively curbed the spread of the epidemic.But the TCM methods in the scheme are all oral prescriptions,less involving non-drug methods.Therefore,I searched the COVID-19 control methods published in various parts of the country,this paper plans to discuss how to improve immunity from the perspective of non-drug methods such as moxibustion,diet therapy,self massage,physical exercise skills and traditional music,hoping can helps the susceptible populations,infected,discharged and medical staff in COVID-19 epidemic. 展开更多
关键词 Corona Virus Disease 2019 Non-drug methods MOXIBUSTION Diet therapy MASSAGE
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Functional physiotherapy method results for the treatment of idiopathic clubfoot
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作者 Noriela Carmen Garcia-Gonzalez Jorge Hodgson-Ravina Armando Aguirre-Jaime 《World Journal of Orthopedics》 2019年第6期235-246,共12页
BACKGROUND Idiopathic clubfoot is a congenital deformity of multifactorial etiology.The initial treatment is eminently conservative;one of the methods applied is the Functional physiotherapy method(FPM),which includes... BACKGROUND Idiopathic clubfoot is a congenital deformity of multifactorial etiology.The initial treatment is eminently conservative;one of the methods applied is the Functional physiotherapy method(FPM),which includes different approaches:Robert Debré(RD)and Saint-Vincent-de-Paul(SVP)among them.This method is based on manipulations of the foot,bandages,splints and exercises adapted to the motor development of the child aimed to achieve a plantigrade and functional foot.Our hypothesis was that the SVP method could be more efficient than the RD method in correcting deformities,and would decrease the rate of surgeries.AIM To compare the RD and SVP methods,specifically regarding the improvement accomplished and the frequency of surgery needed to achieve a plantigrade foot.METHODS Retrospective study of 71 idiopathic clubfeet of 46 children born between February 2004 and January 2012,who were evaluated and classified in our hospital according to severity by the Dimeglio-Bensahel scale.We included moderate,severe and very severe feet.Thirty-four feet were treated with the RD method and 37 feet with the SVP method.The outcomes at a minimum of two years were considered as very good(by physiotherapy),good(by percutaneous heel-cord tenotomy),fair(by limited surgery),and poor(by complete surgery).RESULTS Complete release was not required in any case;limited posterior release was done in 23 cases(74%)with the RD method and 9(25%)with the SVP method(P<0.001).The percutaneous heel-cord tenotomy was done in 2 feet treated with the RD method(7%)and 6 feet(17%)treated with the SVP method(P<0.001).Six feet in the RD group(19%)and twenty-one feet(58%)in the SVP group did not require any surgery(P<0.001).CONCLUSION Our study provides evidence of the superiority of the SVP method over the RD method,as a variation of the FPM,for the treatment of idiopathic clubfoot. 展开更多
关键词 Congenital CLUBFOOT Clubfeet Talipes EQUINOVARUS CONSERVATIVE TREATMENT Physical therapy PHYSIOtherapy techniques CONSERVATIVE methods
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一例场所恐怖症的心理咨询案例报告
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作者 董芳 单美艳 +2 位作者 张甜甜 邓杨 信玉梅 《临床心身疾病杂志》 2025年第1期153-156,共4页
场所恐怖症是对乘坐公共交通工具,处于开放/封闭的空间,排队/处于人群之中,独自离家等情况中的2项或者以上感到明显的恐惧或者焦虑。因想到一旦出现在恐惧场所时害怕难以逃离或者得不到帮助的灾难化想法,个体总是会主动回避这些场景,这... 场所恐怖症是对乘坐公共交通工具,处于开放/封闭的空间,排队/处于人群之中,独自离家等情况中的2项或者以上感到明显的恐惧或者焦虑。因想到一旦出现在恐惧场所时害怕难以逃离或者得不到帮助的灾难化想法,个体总是会主动回避这些场景,这严重影响其社会功能及心理健康水平。作者团队通过联合运用认知行为疗法、呼吸放松法、暴露疗法等方法,修正灾难化想法,降低患者对这些场景的恐惧感,减少回避行为,恢复正常社会功能,增强自信心,促进人格成长。通过对咨询过程的呈现和分析,希望能将此方法、思路推广应用。 展开更多
关键词 场所恐怖症 认知行为疗法 呼吸放松法 非暴力沟通 暴露疗法
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舒神汤联合穴位拔罐治疗慢性顽固性失眠50例
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作者 刘宏平 付筱涵 《中国中医药现代远程教育》 2025年第2期118-121,共4页
目的观察舒神汤联合神门、三阴交穴位拔罐治疗慢性顽固性失眠的临床效果。方法选择100例病程6个月以上的慢性顽固性失眠患者。双盲随机分成治疗组与对照组。对照组行常规治疗,采用安眠类西药;治疗组应用舒神汤,联合神门、三阴交穴位拔... 目的观察舒神汤联合神门、三阴交穴位拔罐治疗慢性顽固性失眠的临床效果。方法选择100例病程6个月以上的慢性顽固性失眠患者。双盲随机分成治疗组与对照组。对照组行常规治疗,采用安眠类西药;治疗组应用舒神汤,联合神门、三阴交穴位拔罐。两组治疗4周,观察治疗效果。结果治疗组治愈率64.0%(32/50)高于对照组的8.0%(4/50),总有效率100.0%(50/50)高于对照组的66.0%(33/50),差异均有统计学意义(P<0.05)。治疗后,治疗组汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分较治疗前明显降低,且治疗组低于对照组,差异有统计学意义(P<0.05);治疗组匹兹堡睡眠质量指数(PSQI)评分较治疗前明显降低,且治疗组低于对照组,差异有统计学意义(P<0.05);治疗组健康状况调查问卷(SF-36)评分较治疗前明显升高,差异有统计学意义(P<0.05),且治疗组高于对照组,差异有统计学意义(P<0.05)。对照组不良反应总发生率为46.0%(23/50),高于治疗组的2.0%(1/50),差异有统计学意义(P<0.05)。结论舒神汤联合神门、三阴交穴位拔罐治疗慢性顽固性失眠安全性高、有显著效果。 展开更多
关键词 不寐 慢性顽固性失眠 疏肝化瘀 养心安神法 舒神汤 穴位拔罐
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六自由度步态分析系统评估膝骨关节炎严重程度的客观准确性
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作者 Shaban Amiri Nzelekela 杨连博 李澎 《中国组织工程研究》 CAS 北大核心 2025年第27期5890-5896,共7页
背景:膝骨关节炎的传统评估方法是基于患者的临床症状、体格检查和影像学表现做出判断,但是这些方法不能反映膝关节的动力学动态变化,不能多维度反映出膝关节的客观状态。六自由度步态分析系统为膝骨关节炎的严重程度提供了更加客观、... 背景:膝骨关节炎的传统评估方法是基于患者的临床症状、体格检查和影像学表现做出判断,但是这些方法不能反映膝关节的动力学动态变化,不能多维度反映出膝关节的客观状态。六自由度步态分析系统为膝骨关节炎的严重程度提供了更加客观、更为实用的一种动态评估方法,为不同患者更精准的治疗方案提供了依据,从而优化患者的治疗策略。目的:综述膝骨关节炎的相关评估系统,将六自由度步态分析与传统评估膝骨关节炎严重程度的方法进行比较,探讨六自由度步态分析在指导膝骨关节炎治疗策略制定方面的应用效果。方法:通过计算机检索Google Scholar、PubMed数据库2002年1月至2023年6月发表的相关文献,英文检索词为“knee osteoarthritis,knee osteoarthritis severity,6DOF gait analysis,evaluation methods,WOMAC,KOOS”;中文检索词为“膝骨关节炎,关节炎评估系统,六自由度步态分析”,通过纳入与排除标准,最终选择65篇文献进行归纳总结。结果与结论:①六自由度步态分析提高了评估膝骨关节炎严重程度的准确性,依据该方法制定的治疗方案显著改善了患者的预后;②基于目前的研究发现,在临床实践中应规范六自由度步态分析与传统评估方法的结合,以便客观准确地评估膝骨关节炎,从而更好地选择治疗方案及评估个体化治疗策略的长期有效性。 展开更多
关键词 膝骨关节炎 评估系统 六自由度步态分析 传统评估方法 个体化治疗
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基于“杂合以治”思想探讨肝纤维化的治疗思路与策略
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作者 萧焕明 施梅姐 +1 位作者 谢玉宝 池晓玲 《西南医科大学学报》 2025年第1期17-20,26,共5页
肝纤维化是多种慢性肝病发展到肝硬化、肝癌的必经中间过程。但目前在肝纤维化的防治中仍然存在较多难点,且尚无肝纤维化防控的有效西药,因此阻断肝纤维化进展至肝硬化、肝癌的任务依然艰巨。长期实践证实,中医药对肝纤维化的预防及治... 肝纤维化是多种慢性肝病发展到肝硬化、肝癌的必经中间过程。但目前在肝纤维化的防治中仍然存在较多难点,且尚无肝纤维化防控的有效西药,因此阻断肝纤维化进展至肝硬化、肝癌的任务依然艰巨。长期实践证实,中医药对肝纤维化的预防及治疗均具有较好的效果,但是如何有效地提高中医治疗肝纤维化的疗效,使中医药在阻断肝纤维化甚至肝硬化、肝癌的发生发展方面更好地发挥优势,也是当前研究的重要课题。早在《黄帝内经》就提出“杂合以治”的治疗思想,从杂合以治的思想出发,整合中医不同疗法的优势,建立中医多方法、多靶点的肝纤维化治疗方案,对于提高肝纤维化的疗效具有重要意义。多维立体系列疗法在杂合以治的思想指导下,长期应用于阻断逆转肝纤维化,效果显著。 展开更多
关键词 肝纤维化 杂合以治 治疗思路 治疗策略
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Experimental study of“Tong Xia”purgative method in ameliorating lung injury in acute necrotizing pancreatitis 被引量:31
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作者 Xia Q Jiang JM +3 位作者 Gong X Chen GY Li L Huang ZW 《World Journal of Gastroenterology》 SCIE CAS CSCD 2000年第1期115-118,共4页
AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.... AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.METHODS Fourteen canines were randomlydivided into 3 groups:the'Tong Xia'treatmentgroup(n = 5)using Dachengqitang;salinecontrol group(n = 5),and the sham operationgroup(n = 4).TNF activity in serum and inbronchoalveolar lavage fluid(BALF),the serumendotoxin levels were measured,and theseverity of lung injury evaluated.RESULTS Elevation of TNF activity was moreprominent in BALF than in serum.TNF activity inserum at 6 and 12 hours and in BALI:wassignificantly decreased in the'Tong Xia'treatment group than in the saline control one(q=21.11,q=12.07,q=9.03,respectively,P【0.01)and the lung injury was significantlyalleviated at 12 hours as compared with that inthe saline group,manifested as amelioration otthe lung wet/ dry weight ratio,decrease inprotein concentration and neutrophils count inBALF,and improvement of pulmonaryinflammatory changes.A positive correlationwas demonstrated between serum TNF activity and endotoxin level.CONCLUSION Hypersecretion of TNF is shownto be one of the major causes of lung injuryduring ANP;'Tong Xia'purgative method couldalleviate the degree of lung injury mediated byTNF. 展开更多
关键词 Subject headings pancreatitis/therapy LUNG disease tumor NECROSIS factor Tong XIA method
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中医治疗糖尿病皮肤瘙痒症研究进展
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作者 江鑫蕊 朱冬雪 李光善 《亚太传统医药》 2025年第1期228-231,共4页
糖尿病皮肤瘙痒症是糖尿病最常见的皮肤并发症,对糖尿病患者日常生活质量和身心健康都产生了极大影响。通过对中医治疗糖尿病皮肤瘙痒症近5年的研究文献进行综述,从不同的角度探讨中医在治疗糖尿病皮肤瘙痒症方面的方法和临床效果,包括... 糖尿病皮肤瘙痒症是糖尿病最常见的皮肤并发症,对糖尿病患者日常生活质量和身心健康都产生了极大影响。通过对中医治疗糖尿病皮肤瘙痒症近5年的研究文献进行综述,从不同的角度探讨中医在治疗糖尿病皮肤瘙痒症方面的方法和临床效果,包括古代及现代医家对该病病因病机的认识、中医内治法、外治法、内外结合法和中西医结合法等。通过总结归纳,发现中医药治疗糖尿病皮肤瘙痒症有良好临床疗效,通过总结研究中的进展与不足,以期为该病相关研究的开展及治疗提供更好的科研思路和临床治疗方法。 展开更多
关键词 糖尿病皮肤瘙痒症 中医内治法 中医外治法 中西医结合疗法 综述
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温补肺肾与祛痰行瘀法联合布地格福治疗慢性阻塞性肺疾病临床观察
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作者 汪丽君 吴婷婷 董日 《中国中医药现代远程教育》 2025年第1期159-162,共4页
目的探究温补肺肾与祛痰行瘀法联合布地格福治疗慢性阻塞性肺疾病(COPD)的临床效果。方法将2021年4月—2022年11月婺源县中医院收治的80例COPD患者随机均分为两组,对照组行常规西医治疗,观察组予温补肺肾与祛痰行瘀法联合布地格福治疗,... 目的探究温补肺肾与祛痰行瘀法联合布地格福治疗慢性阻塞性肺疾病(COPD)的临床效果。方法将2021年4月—2022年11月婺源县中医院收治的80例COPD患者随机均分为两组,对照组行常规西医治疗,观察组予温补肺肾与祛痰行瘀法联合布地格福治疗,两组均持续2个疗程。评价两组的治疗效果及用药安全性。结果观察组的治疗总有效率95.00%(38/40)高于对照组的77.50%(31/40)(P<0.05)。治疗后,两组第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、肺总量(TLC)、呼气峰流速值占预计值百分比(PEF%pred)均提高,且观察组高于对照组(P<0.05)。治疗后,两组动脉血氧分压(PaO_(2))、血氧饱和度(SaO_(2))均提高,且观察组高于对照组(P<0.05);动脉血二氧化碳分压(PaCO_(2))、碱剩余(BE)水平均降低,且观察组低于对照组(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论温补肺肾与祛痰行瘀法联合布地格福治疗COPD,可改善患者肺功能及血气情况,有效且安全。 展开更多
关键词 肺胀 慢性阻塞性肺疾病 温补肺肾法 祛痰行瘀法 布地格福 中西医结合疗法
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Reformatted method for two-dimensional detector arrays measurement data in proton pencil beam scanning 被引量:2
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作者 Meng-Ya Guo Xiu-Fang Li +6 位作者 Jie Wang Qi Liu Xiu-Zhen Deng Man-Zhou Zhang Li-Ren Shen Yue-Hu Pu Zhi-Ling Chen 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2021年第6期83-93,共11页
The spatial resolution of a commercial two-dimensional(2D)ionization chamber(IC)array is limited by the size of the individual detector and the center-to-center distance between sensors.For dose distributions with are... The spatial resolution of a commercial two-dimensional(2D)ionization chamber(IC)array is limited by the size of the individual detector and the center-to-center distance between sensors.For dose distributions with areas of steep dose gradients,inter-detector dose values are derived by the interpolation of nearby detector readings in the conventional mathematical interpolation of 2D IC array measurements.This may introduce significant errors,particularly in proton spot scanning radiotherapy.In this study,by combining logfile-based reconstructed dose values and detector measurements with the Laplacian pyramid image blending method,a novel method is proposed to obtain a reformatted dose distribution that provides an improved estimation of the delivered dose distribution with high spatial resolution.Meanwhile,the similarity between the measured original data and the downsampled logfilebased reconstructed dose is regarded as the confidence of the reformatted dose distribution.Furthermore,we quantify the performance benefits of this new approach by directly comparing the reformatted dose distributions with 2D IC array detector mathematically interpolated measurements and original low-resolution measurements.The result shows that this new method is better than the mathematical interpolation and achieves gamma pass rates similar to those of the original low-resolution measurements.The reformatted dose distributions generally yield a confidence exceeding 95%. 展开更多
关键词 2D ion chamber array detectors Laplacian pyramid image blending High-resolution reformatted methods Pencil beam scanning Proton therapy
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<i>In Vitro</i>Evaluation System of Pharmacokinetics and Irradiation Effect in Boron Neutron Capture Therapy (BNCT) Using Three-Dimensional Artificial Human Tumor Tissue Model 被引量:1
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作者 Shintaro Ishiyama Yoshiya Asano +2 位作者 Minoru Suzuki Mitsuru Akashi Hiroshi Shimoda 《Journal of Cancer Therapy》 2019年第10期835-845,共11页
Boron neutron capture therapy (BNCT) is based on the incorporation of boron-containing drugs to cancer cells and the nuclear reaction of 10B atoms by thermal neutron irradiation results in tumor degeneration. For the ... Boron neutron capture therapy (BNCT) is based on the incorporation of boron-containing drugs to cancer cells and the nuclear reaction of 10B atoms by thermal neutron irradiation results in tumor degeneration. For the development of this therapy, currently, long time and high cost consuming experiments using many animals are required. In this study, we constructed a new in vitro evaluation system for BNCT by combination of an artificial tumor tissue model, comprised of normal human dermal-derived fibroblast (NHDF) and human pancreatic cancer cell line BxPC3, and the optical plastic material CR-39 as a solid state nuclear track detector. Administration of boronophenylalanine (10BPA) as a boron-containing drug and neutron irradiation up to 2.52 × 1012 n/cm2 to the control tissue constructed by NHDF (NHDF3D) and BxPC3 cell loaded tissue (NHDF3D/BxPC3) resulted in detection of 1.6 times higher number of α-ray/recoiled Li particle tracks in NHDF3D/BxPC3 in comparison to NHDF3D, demonstrating that putative irradiation damage to cancer cells can be evaluated by this system. On a cellular level, the hit number of α-ray/recoiled Li particle tracks per single BxPC3 cells and NHDF was evaluated as 5.46 and 1.71, respectively. The tumor and normal tissue ratio (T/N ratio) was 3.19, which was corresponded with those of BPA as 2 - 4 that reported in the previous studies. This new in vitro evaluation system may provide a useful tool for a low cost, labor-saving, and non-animal method for the development of new boron-containing drugs or improvement of BNCT conditions. 展开更多
关键词 Boron Neutron Capture therapy (BNCT) Boronophenylalanine (10BPA) Artificial Human Tumor TISSUE MODEL Cell Accumulation method
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Radiation Sensitivity of <i>in Vitro</i>Evaluation System of Pharmacokinetics in Boron Neutron Capture Therapy (BNCT) Using Three-Dimensional Artificial Human Tumor Tissue Model
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作者 Shintaro Ishiyama Minoru Suzuki 《Journal of Cancer Therapy》 2019年第12期1025-1035,共11页
One of the important matters that must be determined in advance when performing BNCT treatment is the optimization of neutron irradiation time and dose. In this article, following the previous article (2.52 × 101... One of the important matters that must be determined in advance when performing BNCT treatment is the optimization of neutron irradiation time and dose. In this article, following the previous article (2.52 × 1012 n/cm2) (Case 1), double irradiation (5.04 × 1012 n/cm2) was further performed (Case 2) by verifying the radiation sensitivity performance of the artificial tumor tissue NHDF3D/BxPC3 and the possibility of evaluating the optimum neutron dose required for treatment was examined. As a result, although the radiation damage rate in the normal tissue NHDF3D and the tumor tissue BxPC3 increased in proportion to the irradiation dose due to heavy irradiation in Case 1 or more, the increase in the damage rate in the normal tissue exceeded the tumor tissue. Furthermore, the tumor/normal tissue damage ratio T/N ratio showed the maximum value in Case 1, and the dose ratio in Case 2 with a higher dose showed a tendency to decrease. From the above experimental facts, it was shown that irradiation dose optimization is possible to some extent by an evaluation method using an artificial tumor tissue. 展开更多
关键词 Boron Neutron Capture therapy (BNCT) Boronophenylalanine (10BPA) Artificial Human Tumor TISSUE MODEL Cell Accumulation method
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Polydopamine Modified Biomimetic Gold Nanoparticles for Dual Photothermal Therapy
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作者 Zhiming Su Hem Sagar Rim 《Advances in Modern Oncology Research》 2019年第1期6-11,共6页
Our study producted Polydopamine modified gold nanoflowers with controlled morphology for anti-tumor photothermal therapy.The branch structure containsabundant(Au NFs).By adjusting the reduction rate,the dosage of red... Our study producted Polydopamine modified gold nanoflowers with controlled morphology for anti-tumor photothermal therapy.The branch structure containsabundant(Au NFs).By adjusting the reduction rate,the dosage of reducing agent(sodium borohydride)and the reduction temperature,we can adjust tthe morphology and particle size of Au NFs.We found that the lower reaction temperature is,the more abundant the surface branching structure of gold nanoflowers is,by adjusting the reaction temperature.and the largest specific surface area of golden nanopowder was found at 0℃.The results of TEM indicated that with the increase of sodium borohydride,the diameter of gold nano flowers gold nanoflowers decreased and was in the range of 60~100nm,and it has good EPR effect After that,we modify poly(dopamine)(PDA)biomimetic layer on the surface of golden nanoparticles to obtain Au NFS@PDA.Poly(dopamine)has the ability,of photothermal conversion,which can enhance the plasma resonance ability and biocompatibility of gold nanoflowers in the near infrared region.We can control the thickness of polydopamine layer on the surface of gold nanoflowers between 7~15nm by adjusting dopamine DA concentrationgold nanoflowers.Au NFS@PDA was characterized by its morphology and physical properties.We detect(UV-Vis)spectra in the near infrared region.And it showed obvious absorption peaks in the near infrared region of 575~650nm.Under the 808nm irradiation laser,the photothermal conversion of gold nanoflowers and polydopamine can be rapidly increased to 57°C.Fourier Transform Infrared Absorption Spectroscopy(FTIR)and X-ray Diffraction(XRD)analysis showed that polydopamine was modified successfully,Au NFS@PDA and Au NFs had no obvious difference in crystal form.The cell viability test showed that the bionic Au NFS@PDA had good biocompatibility and showed good antitumor activity against HeLa cells under NIR irradiation.The cell viability was only 12%.Therefore,we can use Au NFS@PDA with good biocompatibility as a promising photothermal conversion agent in tumor therapy. 展开更多
关键词 gold nanoflowers POLYDOPAMINE Template-free method CONTROLLABLE Photothermal therapy
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Effect of Wei’s triple nine needling therapy on flash visual evoked potentials in rats with traumatic optic neuropathy
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作者 Shi-Meng Li Jian Zhou +5 位作者 Qi-Ping Wei Jun Wang Wu Sun Yan Wang Jie Wang Yan-Ting Xia 《Journal of Hainan Medical University》 2022年第12期7-12,共6页
Objective:To investigate the effect of Wei’s triple nine needling therapy on the N2-P2 wave of the flash visual evoked potential(FVEP)in rats of the of the transverse directional pulling model.Methods:Thirty-six Wist... Objective:To investigate the effect of Wei’s triple nine needling therapy on the N2-P2 wave of the flash visual evoked potential(FVEP)in rats of the of the transverse directional pulling model.Methods:Thirty-six Wistar rats were randomly grouped,nine were in normal control group without any treatment,and the remaining 27 were surgically modelled in the right eyes.Eighteen of these rats were randomly divided into a Wei’s triple nine needling therapy group and a model group of nine rats each after the TON model was made using the transverse quantitative retraction method.The other 9 rats were sham-operated,and only the optic nerve was exposed without retraction.On the next day of modelling,the Wei’s triple nine needling therapy group was treated with Wei’s triple nine needling therapy for 20 minutes/1 time/1 day for 14 days.The model group,sham-operated group and normal control group were not intervened.Wei's triple nine acupoints were represented as follows:1st link:"Jingming"(BL1)and"Chengqi"(ST1);2nd link:"Sizhukong"(SJ23)penetrating"Taiyang"(EX-HN5);and the third:"Fengchi"(GB 20)and"Taichong"(LV3).The FVEP of each group was observed on 1d,7d and 14d.The FVEP of each group was observed on 1d,7d and 14d.Results:Compared with the model group,the N2 wave latency and P2 wave latency were shortened in the Wei’s triple nine needling therapy on 1d(P<0.05,P<0.01);on 7d,their N2 wave latency was shortened(P<0.01)and the N2-P2 wave amplitude was increased compared with the model group(P<0.05);on 14d,their P2 wave latency was shortened(P<0.05)and the N2-P2 wave amplitude was increased.There was no statistical difference in N2 wave latency,P2 wave latency and N2-P2 wave amplitude in the sham-operated group on 1d,7d and 14d(P>0.05).The delayed N2 and P2 wave latencies in the model group did not improve from 1d to 14d(P>0.05)and the amplitude decreased throughout,showing a significant difference on 14d compared to 1d(P<0.05).In contrast,the N2 wave latency in Wei’s triple nine needling therapy group was not significantly different until 7d to 14d(P<0.05);its P2 wave latency,although significantly delayed from 1d to 7d(P<0.05),recovered on 14d and reached a level that was not statistically different from 1d and 7d(P>0.05).There was also no significant decrease in N2-P2 wave amplitude between 1d and 14d in Wei’s triple nine needling therapy group(P>0.05).Conclusion:In this experiment,the TON rat model was successfully established by the transverse quantitative retraction method,and the treatment of TON rats with Wei’s triple nine needling therapy reduced the P2 wave delay of the FVEP electrophysiological signal and increased the N2-P2 amplitude,which had a certain positive effect on the repair of optic nerve injury,probably related to its effect of improving the conduction function of the optic nerve and protecting the retinal ganglion cells that had not been degenerated and necrosed. 展开更多
关键词 Wei’s triple nine needling therapy Traumatic optic neuropathy Transverse quantitative traction method Flash visual evoked potential Rat
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Observation on the Treatment of Belt Vessel Lumbago by Daoyin method with Acupuncture
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作者 LI Yong-hong SU Feng-zhe +8 位作者 WANG Xiang WANG Dan ZHANG Yu CHEN Xiang YU Xin WANG Hui-min YANG Wen-ting WU Hai-long ZOU Jin-xin 《World Journal of Integrated Traditional and Western Medicine》 2020年第10期1-7,共7页
Objective:To observe the clinical efficacy of Daoyin method with acupuncture on belt vessel type lumbago,and to evaluate the effectiveness of the method.Methods:A total of 54 patients with belt vessel type lumbago who... Objective:To observe the clinical efficacy of Daoyin method with acupuncture on belt vessel type lumbago,and to evaluate the effectiveness of the method.Methods:A total of 54 patients with belt vessel type lumbago who met the inclusion criteria were randomly divided into two groups,with 27 patients in both groups.Patients in the treatment group were treated by Daoyin with acupuncture on the belt vessel,patients in the control group only received acupuncture on the belt vessel.The visual analogue scale,JOA score,ODI score,and SBI score before and after treatment were observed.Results:There were significant differences in the score changes in both groups before and after treatment,and the difference between the treatment group and the control group was significant.The therapeutic effect in the treatment group is better than the control group.Daoyin with acupuncture has a better effect on belt vessel type lumbago. 展开更多
关键词 Belt vessel lumbago Daoyin method Acupuncture therapy
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子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型功能性消化不良临床观察 被引量:1
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作者 王肖萍 田丽 《河北中医》 2024年第3期447-450,455,共5页
目的观察子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型功能性消化不良(FD)的临床疗效。方法将120例脾胃虚寒型FD患者按照随机数字表法分为2组,治疗组60例予子午流注纳子法穴位贴敷联合穴位药熨治疗,对照组60例予多潘立酮片治疗,2... 目的观察子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型功能性消化不良(FD)的临床疗效。方法将120例脾胃虚寒型FD患者按照随机数字表法分为2组,治疗组60例予子午流注纳子法穴位贴敷联合穴位药熨治疗,对照组60例予多潘立酮片治疗,2组均治疗28天。比较2组疗效;比较2组治疗前后主要症状评分变化;比较2组治疗前后焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分变化。结果治疗组总有效率96.67%(58/60),对照组总有效率76.67%(46/60),治疗组疗效优于对照组(P<0.05)。2组治疗后各项主要症状评分及总积分均较本组治疗前降低(P<0.05),治疗后治疗组各项主要症状评分及总积分均低于对照组(P<0.05)。2组治疗后SAS评分、SDS评分均较本组治疗前降低(P<0.05),治疗后治疗组SAS评分、SDS评分均低于对照组(P<0.05)。结论子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型FD疗效显著,可改善患者主要症状及焦虑、抑郁状态。 展开更多
关键词 消化不良 穴位贴敷疗法 药熨疗法 子午流注法
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基于德尔菲法构建再生障碍性贫血患者的健康教育方案 被引量:1
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作者 史爱华 胡蓉华 常晓丽 《中国急救复苏与灾害医学杂志》 2024年第1期106-110,共5页
目的 基于德尔菲法构建再生障碍性贫血(AA)患者的健康教育方案,以期为AA患者提供科学的、合理的健康教育指导。方法 以知信行为理论基础,通过文献回顾、半结构式访谈法拟定健康教育方案的初稿,选取15名专家运用德尔菲法开展2轮咨询,基... 目的 基于德尔菲法构建再生障碍性贫血(AA)患者的健康教育方案,以期为AA患者提供科学的、合理的健康教育指导。方法 以知信行为理论基础,通过文献回顾、半结构式访谈法拟定健康教育方案的初稿,选取15名专家运用德尔菲法开展2轮咨询,基于专家建议对初稿的条目及维度进行修改,最终构建基于知信行理论的AA患者健康教育方案。结果 2轮专家函询问卷回收率均为100%;2轮专家函询中的专家权威程度(Cr)分别为0.893、0.885。第1轮函询中一级条目、二级条目、三级条目专家肯德尔协调系数分别为0.572、0.546、0.512(P<0.05),重要性赋值均数均大于2.97分,变异系数为0.05~0.23,满分率为19.95%~93.42%;第2轮函询中一级条目、二级条目、三级条目专家肯德尔协调系数分别为0.681、0.679、0.548(P<0.05),重要性赋值均数均大于4.08分,变异系数为0.00~0.17,满分率为25.00%~100.00%。最终形成AA患者的健康教育方案[包括3个一级指标(健康知识、健康信念、健康行为)、16个二级指标、55个三级指标]。结论 该研究构建的健康教育方案可信程度较高,指标体系权威性好,权重合理。 展开更多
关键词 再生障碍性贫血 健康教育 免疫抑制治疗 德尔菲法
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背俞穴弹拨法联合背部叩击老年CAP患者排痰效果的研究 被引量:1
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作者 童俊 李军华 熊桂芝 《光明中医》 2024年第7期1358-1360,共3页
目的 探讨老年社区获得性肺炎(CAP)患者运用背俞穴弹拨法联合背部叩击排痰效果。方法 采用随机数字表法将84例患者分为试验组和对照组,各42例,对照组实施常规背部叩击排痰护理,试验组实施背俞穴弹拨法联合背部叩击排痰护理,干预7 d。观... 目的 探讨老年社区获得性肺炎(CAP)患者运用背俞穴弹拨法联合背部叩击排痰效果。方法 采用随机数字表法将84例患者分为试验组和对照组,各42例,对照组实施常规背部叩击排痰护理,试验组实施背俞穴弹拨法联合背部叩击排痰护理,干预7 d。观察2组患者排痰疗效、经皮血氧饱和度和住院时长的差异。结果 干预7 d后,试验组患者排痰疗效优于对照组,排痰有效率、经皮血氧饱均较对照组同期指标有明显改善(P<0.05);且试验组的平均住院日明显缩短(P<0.05)。结论 背俞穴弹拨法联合背部叩击排痰在一定程度上可改善老年CAP患者的排痰能力,提升血氧饱和度,缩短住院时间并降低医疗负担。 展开更多
关键词 社区获得性肺炎 老年病 弹拨法 穴位疗法 推拿疗法
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