A three-dimensional semi-implicit unstructured grid finite volume ocean model

A new three-dimensional semi-implicit finite-volume ocean model has been developed for simulating the coastal ocean circulation, which is based on the staggered C-unstructured non-orthogonal grid in the hor- izontal direction and z-level grid in the vertical direction. The three-dimensional model is discretized by the semi-implicit finite-volume method, in that the free-surface and the vertical diffusion are semi-implicit, thereby removing stability limitations associated with the surface gravity wave and vertical diffusion terms. The remaining terms in the momentum equations are discretized explicitly by an integral method. The partial cell method is used for resolving topography, which enables the model to better represent irregular topography. The model has been tested against analytical cases for wind and tidal oscillation circulation, and is applied to simulating the tidal flow in the Bohal Sea. The results are in good agreement both with the analytical solutions and measurement results.

Three-dimensional numerical modeling of gravity anomalies based on Poisson equation in spacewavenumber mixed domain

In gravity-anomaly-based prospecting, the computational and memory requirements for practical numerical modeling are potentially enormous. Achieving an efficient and precise inversion for gravity anomaly imaging over large-scale and complex terrain requires additional methods. To this end, we have proposed a new topography-capable By performing a two-dimensional Fourier transform in the horizontal directions, threedimensional partial differential equations in the spatial domain were transformed into a group of independent, one-dimensional differential equations engaged with different wave numbers. These independent differential equations are highly parallel across different wave numbers. differential equations with different wave numbers, and the efficiency of solving fixedbandwidth linear equations was further improved by a chasing method. In a synthetic test, a prism model was used to verify the accuracy and reliability of the proposed algorithm by comparing the numerical solution with the analytical solution. We studied the computational precision and efficiency with and without topography using different Fourier transform methods. The results showed that the Guass-FFT method has higher numerical precision, while the standard FFT method is superior, in terms of computation time, for inversion and quantitative interpretation under complicated terrain.

The study on three-dimensional numerical model and fronts of the Jiulong Estuary and the Xiamen Bay

Applying the methods of on-site observation and dynamic model, the research on the fronts at the Jiulong Estuary has been carried out, during which spatial and temporal distribution, dynamic characteristics and formation mechanism of salinity fronts are analyzed and discussed. The research shows that the estuarine fronts mainly lie in the area from the Jiyu Islet to the Haimen Island, outside of Yuweizai to Hulishan cross-section, the near coast of Yuweizai and the south of the Songyu-Gulangyu Channel. The fronts in the former two regions are formed directly by plume, while the one near the coast of Yuweizai is a tidal intrusion front caused by flood current and the one at the south of the Songyu-Gulangyu Channel is the result of current shear transformation. Under normal circumstances, fresh water of the Jiulong River mainly influences the inside of the Xiamen Bay, and when it is in typhoon seasons, plume front can affect the Taiwan Strait and has an effect on the biogeochemical Drocesses in the strait.

Risk Assessment of Coal Mine Water Hazard Based on Three-Dimensional Model of Geology and Underground Space

Mine safety have top-five disasters,which including the water,gas,fire,dust and geological dynamic disaster.The coal mine water disaster is one of the important factors which restricted the development of China’s coal production.It is showed by statistics that 60%of mine accidents are affected by groundwater,which not only result in the production losses,casualties and a variety of

Three-Dimension Mathematical Model of Total Phosphor in the Reservoir and Application

Taking the transport of total phosphor pollutants in the Beijing Miyun reservoir for example,we have obtained three dimensional distributing regularity of total phosphor pollutants by the calculation of the linear interpolation value of each point between horizontal layers. The credibility analysis in allusion to this method was carried out and the programming scheme for realizing this method was set forth.

Three-Dimensional Model Test for Port Engineering with Multi-Directional Waves

-The necessity of using irregular waves, especially multi- directional waves to conduct three-dimensional model tests for port engineering and the test method are described in this paper through an example of model test for a port. The test results show that a deep navigation channel has a large effect on the waves in front of the breakwater near the port entrance and on the wave condition in the port.

THREE-DIMENSIONAL MATHEMATICAL MODEL AND ITS APPLICATION IN THE NEIGHBORHOOD OF THE THREE GORGES RESERVOIR DAM IN THE YANGTZE RIVER

The calculation of flow and sediment transport is one of the most important tasks in river engineering. The task is particularly difficult because a number of complex physical phenomena should be accounted for more realistically in a model with a predictive power. Three-dimensional calculations of river flow and suspended sediment transport are performed in this paper with application in the Three Gorges Reservoir in the Yangtze River. A period of 76 years after the dam is built is simulated and the results are compared with laboratory measurements obtained by Tsinghua University whereby the model is verified and calibrated. Generally speaking, the calculated results agree well with the experiments, demonstrating that the present model can be used for flow and sediment transport prediction in rivers.

A Novel Three-Dimensional Mouse Embryonic Implantation Model In Vitro

To regenerate three-dimensional endometrium in vitro as a novel model for studying the mechanism of implantation of embryos, the luminal epithelial cells and stromal cells of the rabbit uterus were separated and cultured in vitro. The type Ⅰ mouse tail collagen was used as scaffolding material. The stromal cells were inoculated in the type I mouse tail collagen, and the luminal epithelial cells were inoculated on the type i mouse tall collagen to regenerate the endometrium in vitro. The regenerated endometrium was cultured in DMEM-F/12 media containing 100 nmol L^-1 progesterone, 10 nM β-estradiol, and 10% fetal bovine serum （FBS） for 3 d. The media were then replaced with CZB containing 100 nM progesterone, 10 nmol L-1 β-estradiol, and 10% FBS, and the mouse blastulas were co-cultured with it. The results of scanning electronic micrography showed that the epithelial cells on the surface of the reconstructed endometrium were covered with numerous slender microvilli and some epithelial cells protruded pinopodes. After culturing for 12 h with the mouse blastula, the shedding, attachment, and implantation of the blastula were observed. The blastula can escape from zona pellucida and attach to the three-dimensional endometrium and is then implanted into it. This study showed that the reconstructed three-dimensional endometrium can serve as a robust embryo implantation model in vitro.

Numerical Simulation of Saline Intrusion and Purging in Long SeaOutfalls with Three-Dimensional Model

Saline intrusion into marine sewage ouffalls will greatly decrease the efficiency of sewage disposal. In order to investigate the mechanisms of this flow, in this paper, a three-dimensional numerical model based on FVM （Finite Volume Method） is established, The RNG κ-ε model is selected for turbulence modeling. The time-averaged vohtme fraction equations are introduced to simulate the stratification and inteffaeial exchange of sewage and seawater in outfalls. Validity of the established three-dimensional numerical model is evaluated by comparisons of numerical results with experimental data. With this three-dimensional numerical model, the internal flow characteristics in ouffalls for different sewage discharges are simulated. The results indicate that for a low sewage discharge, saline circulates in the outfall due to intrusion and both the inflowing momentum and the inteffaeial turbulent mixing are important mechanisms to extrude the saline. For a high sewage discharge, saline intrusion could be avoided. The inflow momentum is the main mechanism to extrude the saline and the inteffacial turbulent mixing is nut important relatively. Even at a high sewage discharge, the saline wedge would be retained in the main ouffall pipe after the risers are purged. It takes a long time for this saline wedge to be extruded by interracial turbulent mixing.

Cosmological Model in Four Time and Four Space Dimensions

We develop a cosmological model in a physical background scenario of four time and four space dimensions ((4+4)-dimensions or (4+4)-universe). We show that in this framework the (1+3)-universe is deeply connected with the (3+1)-universe. We argue that this means that in the (4+4)-universe there exists a duality relation between the (1+3)-universe and the (3+1)-universe.

Development of a Percentile Based Three-dimensional Model of the Buttocks in Computer System

There are diverse products related to human buttocks, which need to be designed, manufactured and evaluated with 3D buttock model. The 3D buttock model used in present research field is just simple approximate model similar to human buttocks. The 3D buttock percentile model is highly desired in the ergonomics design and evaluation for these products. So far, there is no research on the percentile sizing system of human 3D buttock model. So the purpose of this paper is to develop a new method for building three-dimensional buttock percentile model in computer system. After scanning the 3D shape of buttocks, the cloud data of 3D points is imported into the reverse engineering software（Geomagic） for the reconstructing of the buttock surface model. Five characteristic dimensions of the buttock are measured through mark-points after models being imported into engineering software CATIA. A series of space points are obtained by the intersecting of the cutting slices and 3D buttock surface model, and then are ordered based on the sequence number of the horizontal and vertical slices. The 1st, 5th, 50 th, 95 th, 99 th percentile values of the five dimensions and the spatial coordinate values of the space points are obtained, and used to reconstruct percentile buttock models. This research proposes a establishing method of percentile sizing system of buttock 3D model based on the percentile values of the ischial tuberosities diameter, the distances from margin to ischial tuberosity and the space coordinates value of coordinate points, for establishing the Nth percentile 3D buttock model and every special buttock types model. The proposed method also serves as a useful guidance for the other 3D percentile models establishment for other part in human body with characteristic points.

Simulation-Based Construction of Three-Dimensional Process Model for Punching Cartridge Cases

A method of constructing three-dimensional process model for the punching cartridge cases is presented based on DEFORM simulation analysis. Using DEFORM software,the finite element simulation models for the punching and forming process of cartridge cases are established,and the corresponding simulation result model of each intermediate procedure is obtained by continuously performing the forming process simulation. The simulation model cannot annotate size and process information due to poor interface between DEFORM software and CAD software. Thus,a 3D annotation module is developed with secondary development technology of UG NX software. Consequently,the final process model with dimension and process information is obtained. Then,with the current 3D process management system,the 3D punching and forming process design of cartridge cases can be completed further. An example is also provided to illustrate that the relative error between the simulation process model and the physical model is less than 2%,which proves the validity and reliability of the proposed method in this study.

Construction and Analysis of Three-dimensional Graphic Model of Single-chain Fv Derived from an Anti-human Placental Acidic Isoferritin Monoclonal Antibody by Computer

Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein-predicting computer algorithm on Silicon graphic computer station. The structure, surface static electricity and hydrophobicity of scFv were investigated. Computer graphic modelling indicated that all regions of scFv including the linker, variable regions of the heavy (VH) and light (VL) chains were suitable. The VH region and the VL region were involved in composing the 'hydrophobic pocket'. The linker was drifted away VH and VL regions. The complementarity determining regions (CDRs) of VH and VL regions surrounded the 'hydrophobic pocket'. This study provides a theory basis for improving antibody affinity, investigating antibody structure and analyzing the functions of VH and VL regions in antibody activity.

Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling

Three-dimensional(3D)culture systems are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than the monolayer cultures.In cancer and stem cell research,the natural cell characteristics and architectures are closely mimicked by the 3D cell models.Thus,the 3D cell cultures are promising and suitable systems for various proposes,ranging from disease modeling to drug target identification as well as potential therapeutic substances that may transform our lives.This review provides a comprehensive compendium of recent advancements in culturing cells,in particular cancer and stem cells,using 3D culture techniques.The major approaches highlighted here include cell spheroids,hydrogel embedding,bioreactors,scaffolds,and bioprinting.In addition,the progress of employing 3D cell culture systems as a platform for cancer and stem cell research was addressed,and the prominent studies of 3D cell culture systems were discussed.

NUMERICAL MODELLING OF THREE-DIMENSION CHARACTERISTICS OF WIND-DRIVEN CURRENT IN THE BOHAI SEA

Three- dimension (3-D) wind-driven currents in the Bohai Sea in both winter and summer are calculated by using a 3- D barotropic steady model, and the results are consistent with observed flow char -acteristics. Based on the results, 3- D characteristics of flow, currents at different depths, compensated flow in the lower layer , long and narrow alongshore current, the area of upwelling and downwelling, main circulation in vertical profile, and the current in Bohai Strait are discussed.

Research on the Three-dimensional Modeling and Optimization of a Virtual Tower Crane Based on 3DS Max, Solidworks and EON Professional

Three-dimensional modeling of virtual hoisting machinery is the critical works to structure the system of virtual construction, and the foundation to realize intelligent and interactive virtual hoisting. Aimed at enhancing the requests of image quality and stability of the virtual construction scene, taking a tower crane for example. We studied the technology of three-dimensional modeling and optimization of a virtual tower crane, and a method named two-stage model optimization was put forward. This depended on the modeling stage using Solidworks and 3DS Max and the performance optimization stage in EON. The practice of software development indicates that the proposed methods of three-dimensional modeling and optimization could satisfy the performance request of virtual construction system and be popularized to other virtual system.

Three-dimensional tidal current numerical model of the Oujiang Estuary

The characteristics of three-dimensional （3-D） tidal current in the Oujiang Estuary are investigated according to in situ observations. The Oujiang Estuary has features of irregular coastline, complex topography, many islands, moveable boundary, and submerged dyke, therefore, σ 3-D numerical model oil an unstructured triangular grid has been degeloped. The σ coordinate transforination, the moveable boundary and submerged dyke treatment techniques were employed in the model so it is suitable for the tidal simulations in the Oujing Estuary with submerged dyke and moveable boundary problems. The model is evaluated with the in situ data, and the results show that the calculated water elevations at 19 stations and currents at 19 profiler stations are in good agreement with measured data both in magnitude and phase. This numerical model is applied to the 3-D tidal circulation simulations of experiments in stopping flow transport through the South Branch of the Oujiang Estuary, and the feasibility to cutoff the flow in the South Branch of the Oujiang Estuary is demonstrated by numerical simulation experiments. The developed numerical model simulated the 3-D tidal current circulations in complicated coastal and estuarine waters very well.

Three-dimensional fuzzy logic system for process modeling and control

The traditional fuzzy logic system （FLS） can only model and control the process in two-dimensional nature. Many of real-world systems are of multidimensional features, such as, thermal and fluid processes with spatiotemporal dynamics, biological systems, or decision-making processes that contain stochastic and imprecise uncertainties. These types of systems are difficult for the traditional FLS to model and control because they require a third dimension for spatial or probabilistic information. The type-2 fuzzy set provides the possibility to develop a three-dimensional fuzzy logic system for modeling and controlling these processes in three-dimensional nature.

Autologous nerve graft repair of different degrees of sciatic nerve defect:stress and displacement at the anastomosis in a three-dimensional finite element simulation model

In the repair of peripheral nerve injury using autologous or synthetic nerve grafting, the mag- nitude of tensile forces at the anastomosis affects its response to physiological stress and the ultimate success of the treatment. One-dimensional stretching is commonly used to measure changes in tensile stress and strain; however, the accuracy of this simple method is limited. There- fore, in the present study, we established three-dimensional finite element models of sciatic nerve defects repaired by autologous nerve grafts. Using PRO E 5.0 finite element simulation software, we calculated the maximum stress and displacement of an anastomosis under a 5 N load in 10-, 20-, 30-, 40-mm long autologous nerve grafts. We found that maximum displacement increased with graft length, consistent with specimen force. These findings indicate that three-dimensional finite element simulation is a feasible method for analyzing stress and displacement at the anas- tomosis after autologous nerve grafting.

Three-Dimensional Tidal Model and Its Application to Numerical Simulation of Water Quality in Coastal Waters

The turbulence mechanism plays an important part in the mixing process and momentum transfer of turbulence. A three-dimensional Prandtl mixing length tidal model has been developed to simulate tidal flows and water quality. The eddy viscosities and diffusivities are computed from the Prandtl mixing length model. In order to model the water quality of an estuary or coastal area many interdependent processes need to be simulated. These may be conveniently separated into three main groups: transport and mixing processes, biochemical interaction of water quality variables and the utilization and re-cycling of nutrients by living matter. The model simulates full oxygen and nutrient balance, primary productivity and the transport, reaction mechanism and fate of pollutants over tidal time-scales. The model is applied to numerical simulation of tidal flows and water quality in Dalian Bay. The model has been calibrated against a limited data set of historical water quality observations and in general demonstrates excellent agreement with all available data.