Three-dimensional time-of-flight magnetic resonance angiography combined with high resolution T2-weighted imaging in preoperative evaluation of microvascular decompression

BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and HFS caused by NVC. The judgement of NVC is a critical step in the preoperative evaluation of MVD, which is related to the effect of MVD treatment. Magnetic resonance imaging(MRI) technology has been used to detect NVC prior to MVD for several years. Among many MRI sequences, three-dimensional time-of-flight magnetic resonance angiography(3D TOF MRA) is the most widely used. However, 3D TOF MRA has some shortcomings in detecting NVC. Therefore, 3D TOF MRA combined with high resolution T2-weighted imaging(HR T2WI) is considered to be a more effective method to detect NVC.AIM To determine the value of 3D TOF MRA combined with HR T2WI in the judgment of NVC, and thus to assess its value in the preoperative evaluation of MVD.METHODS Related studies published from inception to September 2022 based on PubMed, Embase, Web of Science, and the Cochrane Library were retrieved. Studies that investigated 3D TOF MRA combined with HR T2WI to judge NVC in patients with TN or HFS were included according to the inclusion criteria. Studies without complete data or not relevant to the research topics were excluded. The Quality Assessment of Diagnostic Accuracy Studies checklist was used to assess the quality of included studies. The publication bias of the included literature was examined by Deeks’ test. An exact binomial rendition of the bivariate mixed-effects regression model was used to synthesize data. Data analysis was performed using the MIDAS module of statistical software Stata 16.0. Two independent investigators extracted patient and study characteristics, and discrepancies were resolved by consensus. Individual and pooled sensitivities and specificities were calculated. The I_(2) statistic and Q test were used to test heterogeneity. The study was registered on the website of PROSERO(registration No. CRD42022357158).RESULTS Our search identified 595 articles, of which 12(including 855 patients) fulfilled the inclusion criteria. Bivariate analysis showed that the pooled sensitivity and specificity of 3D TOF MRA combined with HR T2WI for detecting NVC were 0.96 [95% confidence interval(CI): 0.92-0.98] and 0.92(95%CI: 0.74-0.98), respectively. The pooled positive likelihood ratio was 12.4(95%CI: 3.2-47.8), pooled negative likelihood ratio was 0.04(95%CI: 0.02-0.09), and pooled diagnostic odds ratio was 283(95%CI: 50-1620). The area under the receiver operating characteristic curve was 0.98(95%CI: 0.97-0.99). The studies showed no substantial heterogeneity(I2 = 0, Q = 0.001 P = 0.50).CONCLUSION Our results suggest that 3D TOF MRA combined with HR T2WI has excellent sensitivity and specificity for judging NVC in patients with TN or HFS. This method can be used as an effective tool for preoperative evaluation of MVD.

Wide-Area Delay-Dependent Adaptive Supervisory Control of Multi-machine Power System Based on Improve Free Weighting Matrix Approach

The paper demonstrates the possibility to enhance the damping of inter-area oscillations using Wide Area Measurement (WAM) based adaptive supervisory controller (ASC) which considers the wide-area signal transmission delays. The paper uses an LMI-based iterative nonlinear optimization algorithm to establish a method of designing state-feedback controllers for power systems with a time-varying delay. This method is based on the delay-dependent stabilization conditions obtained by the improved free weighting matrix (IFWM) approach. In the stabilization conditions, the upper bound of feedback signal’s transmission delays is taken into consideration. Combining theoriesof state feedback control and state observer, the ASC is designed and time-delay output feedback robust controller is realized for power system. The ASC uses the input information from Phase Measurement Units (PMUs) in the system and dispatches supplementary control signals to the available local controllers. The design of the ASC is explained in detail and its performance validated by time domain simulations on a New England test power system (NETPS).

Patch-based vehicle logo detection with patch intensity and weight matrix

A patch-based method for detecting vehicle logos using prior knowledge is proposed.By representing the coarse region of the logo with the weight matrix of patch intensity and position,the proposed method is robust to bad and complex environmental conditions.The bounding-box of the logo is extracted by a thershloding approach.Experimental results show that 93.58% location accuracy is achieved with 1100 images under various environmental conditions,indicating that the proposed method is effective and suitable for the location of vehicle logo in practical applications.

Drawing Weighted Directed Graph from It's Adjacency Matrix

This paper proposes an algorithm for building weighted directed graph, defmes the weighted directed relationship matrix of the graph, and describes algorithm implementation using this matrix. Based on this algorithm, an effective way for building and drawing weighted directed graphs is presented, forming a foundation for visual implementation of the algorithm in the graph theory.

Syngeneic implantation of mouse hepatic progenitor cell-derived three-dimensional liver tissue with dense collagen fibrils

BACKGROUND Liver transplantation is a therapy for irreversible liver failure;however,at present,donor organs are in short supply.Cell transplantation therapy for liver failure is still at the developmental stage and is critically limited by a shortage of human primary hepatocytes.AIM To investigate the possibility that hepatic progenitor cells(HPCs)prepared from the portal branch-ligated hepatic lobe may be used in regenerative medicine,we attempted to enable the implantation of extracellular matrices containing organoids consisting of HPC-derived hepatocytes and non-parenchymal cells.METHODS In vitro liver organoid tissue has been generated by accumulating collagen fibrils,fibroblasts,and HPCs on a mesh of polylactic acid fabric using a bioreactor;this was subsequently implanted into syngeneic wild-type mice.RESULTS The in vitro liver organoid tissues generated transplantable tissues in the condensed collagen fibril matrix and were obtained from the mouse through partial hepatectomy.CONCLUSION Liver organoid tissue was produced from expanded HPCs using an originally designed bioreactor system.This tissue was comparable to liver lobules,and with fibroblasts embedded in the network collagen fibrils of this artificial tissue,it is useful for reconstructing the hepatic interstitial structure.

Spatial weight matrix in dimensionality reduction reconstruction for microelectromechanical system-based photoacoustic microscopy

A micro-electromechanical system(MEMS)scanning mirror accelerates the raster scanning of optical-resolution photoacoustic microscopy(OR-PAM).However,the nonlinear tilt angular-voltage characteristic of a MEMS mirror introduces distortion into the maximum back-projection image.Moreover,the size of the airy disk,ultrasonic sensor properties,and thermal effects decrease the resolution.Thus,in this study,we proposed a spatial weight matrix(SWM)with a dimensionality reduction for image reconstruction.The three-layer SWM contains the invariable information of the system,which includes a spatial dependent distortion correction and 3D deconvolution.We employed an ordinal-valued Markov random field and the Harris Stephen algorithm,as well as a modified delay-and-sum method during a time reversal.The results from the experiments and a quantitative analysis demonstrate that images can be effectively reconstructed using an SWM;this is also true for severely distorted images.The index of the mutual information between the reference images and registered images was 70.33 times higher than the initial index,on average.Moreover,the peak signal-to-noise ratio was increased by 17.08%after 3D deconvolution.This accomplishment offers a practical approach to image reconstruction and a promising method to achieve a real-time distortion correction for MEMS-based OR-PAM.

Research on consistency measurement and weight estimation approach of hybrid uncertain comparison matrix

The consistency measurement and weight estimation approach of the hybrid uncertain comparison matrix in the analytic hierarchy process （AHP） are studied. First, the decision-making satisfaction membership function is defined based on the decision making＇s allowable error. Then, the weight model based on the maximal satisfactory consistency idea is suggested, and the consistency index is put forward. Moreover, the weight distributing value model is developed to solve the decision making misleading problem since the multioptimization solutions in the former model. Finally, the weights are ranked based on the possibility degree approach to obtain the ultimate order.

A novel trilinear decomposition algorithm:Three-dimension non-negative matrix factorization

Non-negative matrix factorization （NMF） is a technique for dimensionality reduction by placing non-negativity constraints on the matrix. Based on the PARAFAC model, NMF was extended for three-dimension data decomposition. The three-dimension nonnegative matrix factorization （NMF3） algorithm, which was concise and easy to implement, was given in this paper. The NMF3 algorithm implementation was based on elements but not on vectors. It could decompose a data array directly without unfolding, which was not similar to that the traditional algorithms do, It has been applied to the simulated data array decomposition and obtained reasonable results. It showed that NMF3 could be introduced for curve resolution in chemometrics.

Optimal strategy of searching FPD weights scanning matrix using GA-PSO

This paper discusses a kind of optimal method used for searching flat panel display （FPD） scanning matrix. The method adopts bionic algorithm： genetic algorithm （GA） and particle swarm optimization （PSO） algorithm. The method using single GA is more time-consuming, and the search efficiency is low in later evolution; the PSO algorithm is easily falling into the local optimal solution and appears the premature convergent phenomenon. Hence, a hybrid approach of GAPSO is found to optimize the search for high grayscale weights scanning matrix. Finally in the acceptable time, it finds a weight scanning matrix （WSM） of 256 gray scales with Matlab, whose scanning efficiency reaches 94.73% and the linearity is very good.

Correction to: Spatial weight matrix in dimensionality reduction reconstruction for micro-electromechanical system-based photoacoustic microscopy

Following publication of the original article[1],the keywords are missing in the article.Keywords:Photoacoustic microscopy,Spatial weight matrix,Dimensionality reduction,Distortion correction,Mutual information The original article has been updated.

基于Matrix Profile的时间序列分割技术改进

时间序列分割是数据挖掘领域中的一个重要研究方向.目前基于矩阵轮廓(matrix profile,MP)的时间序列分割技术得到了越来越多研究人员的关注,并且取得了不错的研究成果.不过该技术及其衍生算法仍然存在不足:首先,基于矩阵轮廓的快速低代价语义分割算法中对给定活动状态的时间序列分割时,最近邻之间通过弧进行连接,会出现弧跨越非目标活动状态匹配相似子序列问题;其次,现有提取分割点算法在提取分割点时采用给定长度窗口,容易得到与真实值偏差较大的分割点,降低准确性.针对以上问题,提出一种限制弧跨越的时间序列分割算法(limit arc curve cross-FLOSS,LAC-FLOSS),该算法给弧添加权重,形成一种带权弧,并通过设置匹配距离阈值解决弧的跨状态子序列误匹配问题.此外,提出一种改进的提取分割点算法(improved extract regimes,IER),它通过纠正弧跨越(corrected arc crossings,CAC)序列的形状特性,从波谷中提取极值,避免直接使用窗口在非拐点处取到分割点的问题.在公开数据集datasets_seg和MobiAct上面进行对比实验,验证以上两种解决方案的可行性和有效性.

A Note on the Spectral Radius of Weighted Signless Laplacian Matrix

A weighted graph is a graph that has a numeric label associated with each edge, called the weight of edge. In many applications, the edge weights are usually represented by nonnegative integers or square matrices. The weighted signless Laplacian matrix of a weighted graph is defined as the sum of adjacency matrix and degree matrix of same weighted graph. In this paper, a brief overview of the notation and concepts of weighted graphs that will be used throughout this study is given. In Section 2, the weighted signless Laplacian matrix of simple connected weighted graphs is considered, some upper bounds for the spectral radius of the weighted signless Laplacian matrix are obtained and some results on weighted and unweighted graphs are found.

New Approach of Stability for Time-Delay Takagi-Sugeno Fuzzy System Based on Fuzzy Weighting-Dependent Lyapunov Functionals

This paper deals with the stability of Takagi-Sugeno fuzzy models with time delay. Using fuzzy weighting- dependent Lyapunov-Krasovskii functionals, new sufficient stability criteria are established in terms of Linear Matrix Inequality;hence the stability bound of upper bound delay time can be easily estimated. Finally, numeric simulations are given to validate the developed approach.

Phosphorylation and biosynthesis of high molecular weight proteins of tumor nuclear matrix

Our previous studies showed a predominance of high molecular weight protein group in tumor nuclear matrices. contrary to normal cells, Proteins of this group are Preferentially phosphorylated. Phosphoproteins of hepatoma nuclear matrix are selectively subjected to rapid proteolysis. By alkali treatment and a monoclonal antibody against phosphotyrosyl residue the presence of two high molecular weight bands of phosphotyrosyl-containing proteins was defected in nuclear matrices of tumor but not of normal liver cells. High molecular weight protein group of tumor nuclear matrices revealed also a rapid turnover and preferential incorporation of labeled amino acids selectively inhibited by chioramphenicol.

关于赋权非正则图的A_(α)特征值和特征向量

设G_(ω)=(G,ω)是一个赋权图,其邻接矩阵和赋权度对角矩阵分别A(G_(ω))和D(G_(ω))。对于α∈[0,1],G_(ω)的A_(α)-矩阵为A_(α)(G_(ω))=αD(G_(ω))+(1-α)A(G_(ω))。对于连通赋权非正则图G_(ω),给出了其关于A_(α)-特征值的一些界,并得到了A_(α)-谱半径对应的特征向量中最大分量与最小分量比值的下界。

基于现场可编程门阵列的矩阵求逆算法设计

由于自适应抗干扰算法在更新最优权值时存在时间延时,导致很难满足动态环境下的权值更新率要求。针对该情况已有学者对如何实现快速采样矩阵求逆算法进行研究,但仍存在只适用于低维矩阵,且权值更新率慢的问题。为解决上述问题,提出了一种基于Cholesky分解的采样矩阵求逆算法实现架构。该实现架构主要包括协方差矩阵计算模块、Cholesky分解模块、计算下三角矩阵L的逆矩阵模块、三角矩阵相乘和权值计算模块。设计采用流水线加状态机实现结构有效地解决了因高阶采样矩阵求逆运算量大产生的权值更新率慢的问题。仿真结果表明,在现场可编程门阵列(field programmable gate array,FPGA)的硬件平台上,对于56阶采样矩阵,在100 MHz工作频率下,一次权值的更新时间仅需要1.2 ms。本文所提的实现架构为自适应抗干扰快速求解权值提供了一种切实可行的解决方案,对存在类似需求的权值求解系统具有一定的参考价值。

加权信息量支持下融合InSAR形变特征的滑坡易发性评价

使用SBAS-InSAR处理六盘水市水城区2018-07~2019-08共69景Sentinel-1A卫星影像,获取地表形变作为动态评价因子,用于完善传统滑坡易发性评价研究缺乏动态特征数据应用的问题。结果表明,使用10种静态评价因子融合InSAR形变特征数据作为动态评价因子,在耦合层次分析法与信息量法的加权信息量模型下对比仅使用静态特征数据,ROC曲线下面积分别为0.756 02和0.888 68,模型性能提升约13.3%;再将历史灾害点叠加于2种分区图下检验分区精度,相比于未融入形变特征,融入形变特征可纠正约12.44%的误分类区域,能较好地提升分区的可靠性。

电子传递链对阿尔兹海默病的影响分析

阿尔兹海默病(Alzheimer’s disease,AD)是一种神经退行性疾病.临床上以记忆障碍、视空间技能损害、执行功能障碍以及人格行为改变等全面性痴呆表现为特征.AD致病源现今不明确,其中有毒物质损害使得脑内区域性能量代谢减退是AD发生的病因特征之一,而电子传递链(ETC)在能量代谢中扮演着重要角色.通过差异分析(LIMMA)及加权基因共表达网络(WGCNA)构建获得聚类基因,并对聚类后基因进行生理分析(GO)、通路分析(KEGG)后锁定ETC,以及对其进行表达量分析及相关系数矩阵的构建,并结合临床指标(MMSE)解释说明,最终验证了ETC的异常对阿尔兹海默病存在影响的事实.

基于一致性的赋权方法在课程过程性评价中的应用

针对课程平时成绩的权重比例,构建采用客观赋权法确定权重的动态代数模型.基于平时成绩的各项得分,分析项目之间的一致度,应用矩阵理论对权重进行一致性检验,给出一致性最强的权重比例.结合实例计算最优权重.

饮用水中高分子量消毒副产物的检测识别方法

消毒是饮用水处理过程中的重要步骤,但普遍采用的氯系消毒剂在杀灭细菌病毒的同时,能产生大量具有“三致”效应的卤代消毒副产物(DBPs),严重威胁了饮用水的化学安全.研究人员已在饮用水中陆续检测并识别出700多种DBPs,但这些已知DBPs均为分子量小于800 Da的低分子量DBPs,目前对高分子量DBPs的认识还较为有限.本研究建立了基于基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)的高分子量DBPs检测方法,发现在基质为2,5-二羟基苯甲酸,阳离子化试剂为三氟乙酸钠,使用三明治法点靶,反射-正离子模式,90%激光强度时,信噪比和信号重现性达到最优,信噪比之和达到了136.2,变异系数(CV)则为4.77%.利用上述方法,在模拟饮用水中检测到5种新的高分子量DBPs.在此基础上,通过同位素模式分析、TOF/TOF串联质谱和数据库验证,建立了针对未知高分子量DBPs的分子式/结构式识别方法,确定新的高分子量DBPs为寡糖羧酸类物质.