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颈部钝性外伤致甲状腺巨大血肿1例
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作者 马旭 张瑾 +2 位作者 李德民 董念 吴允刚 《中国耳鼻咽喉头颈外科》 CSCD 2024年第10期677-678,共2页
1临床资料患者,男,69岁,主因“颈部外伤6 h”于2023-08-03入院。6 h前患者被车扶手撞伤颈部,无皮肤黏膜出血,伤后约1 h自觉呼吸不畅,咽部不适,就诊于当地医院,建议上级医院就诊,遂转入济宁医学院附属医院。急诊行颈部CT示:颈部左侧-上... 1临床资料患者,男,69岁,主因“颈部外伤6 h”于2023-08-03入院。6 h前患者被车扶手撞伤颈部,无皮肤黏膜出血,伤后约1 h自觉呼吸不畅,咽部不适,就诊于当地医院,建议上级医院就诊,遂转入济宁医学院附属医院。急诊行颈部CT示:颈部左侧-上纵隔见一团块状略高密度影,大小约7.6 cm×5.7 cm×9.4 cm,甲状腺分界不清,喉腔狭窄(图1A)。以“颈部外伤、颈部血肿?”收入重症监护室治疗,立即给予气管插管,接呼吸机辅助呼吸。 展开更多
关键词 颈部损伤(Neck Injuries) 甲状腺(Thyroid gland) 血肿(Hematoma) 气道阻塞(Airway Obstruction)
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Dignosis and Treatment of Primary Malignant Lymphoma of the Thyroid Gland 被引量:4
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作者 Peter Meusers Britta Elo Andrea Wittig 《The Chinese-German Journal of Clinical Oncology》 CAS 2003年第4期219-223,252,共6页
Primary malignant lymphoma of the thyroid gland is a rare disease comprising about 1%–3% of the thyroid malignancies, and this uncommon lymphoma represent less than 1% of all non-Hodgkinlymphomas (NHL). According to ... Primary malignant lymphoma of the thyroid gland is a rare disease comprising about 1%–3% of the thyroid malignancies, and this uncommon lymphoma represent less than 1% of all non-Hodgkinlymphomas (NHL). According to the modified Ann-Arbor-Classification primary thyroid lymphoma by definition is a lymphoma that is restricted to the thyroid gland (stage I E ) or involves the thyroid gland and supradiaphragmatic predominantly adjacent thyroid lymph nodes (stage II E ). Primary thyroid lymphoma is a heterogenous disease encompassing a wide variety of lymphoma entities. The diagnosis and treatment of this lymphoma are emphasis of this article. Key words thyroid gland - lymphoma - diagnosis - treatment 展开更多
关键词 thyroid gland LYMPHOMA DIAGNOSIS TREATMENT
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Extrapleural solitary fibrous tumor of the thyroid gland: A case report and review of literature 被引量:3
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作者 Yong Joon Suh Jung Ho Park +1 位作者 Jae Hyeon Jeon Sanchir-Erdene Bilegsaikhan 《World Journal of Clinical Cases》 SCIE 2020年第4期782-789,共8页
BACKGROUND Solitary fibrous tumor(SFT)is an uncommon mesenchymal neoplasm that arises from the pleura.A few SFTs have also been described in extrapleural sites.However,SFT of the thyroid gland is rare.Here,we report a... BACKGROUND Solitary fibrous tumor(SFT)is an uncommon mesenchymal neoplasm that arises from the pleura.A few SFTs have also been described in extrapleural sites.However,SFT of the thyroid gland is rare.Here,we report a case of extrapleural SFT on the thyroid gland,in addition to a literature review.CASE SUMMARY A 59-year-old man visited our hospital in July 2017 complaining of a large mass in his neck.His thyroid function test results,including antibody levels,were within the normal limits.Ultrasonography showed a 4.7 cm×4.0 cm×3.2 cm solitary mass of intermediate suspicion in the left thyroid lobe.A fine-needle aspiration biopsy was subsequently performed.The pathologist reported a benign follicular lesion.However,the size of this nodule increased to 5.5 cm×5.0 cm×3.4 cm by April 2018.After a multidisciplinary discussion,a left lobectomy was performed in May 2018.The specimen showed a well-demarcated,partly encapsulated,soft nodule of whitish and tan/brown color on the cut surface.Light microscopy revealed high cellularity with moderate cytologic atypia.The mitotic count was 5/10 high-power fields.There was no tumor necrosis or lymphovascular invasion.The tumor was CD34-positive and signal transducer and activator of transcription 6-positive.Neither thyroid transcription factor-1 nor cytokeratin expression was detected.The Ki-67 showed intermediate proliferative activity.The final diagnosis was extrapleural SFT of the thyroid gland with a clear resection margin.The patient was discharged without complication three days after the surgery.CONCLUSION In the literature,extrapleural SFT of the thyroid gland has been reported to behave indolently with the capacity for recurrence and rare metastasis,although surgical resection is the treatment of choice.Understanding this disease entity is important for accurate diagnosis and proper management. 展开更多
关键词 Solitary fibrous tumor Mesenchymal neoplasm Thyroid gland SURGERY Case report REVIEW
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Metastasis to the thyroid gland from primary breast cancer presenting as diffuse goiter:A case report and review of literature 被引量:1
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作者 Wen Wen Heng Jiang +1 位作者 Hsin-Yu Wen Yu-Lan Peng 《World Journal of Clinical Cases》 SCIE 2022年第3期1106-1115,共10页
BACKGROUND Metastasis to the thyroid gland(TM)from primary breast cancer is uncommon and usually presents as thyroid nodules;however,diffuse goiter without thyroid nodules is the first sign of TM in rare cases.Skip me... BACKGROUND Metastasis to the thyroid gland(TM)from primary breast cancer is uncommon and usually presents as thyroid nodules;however,diffuse goiter without thyroid nodules is the first sign of TM in rare cases.Skip metastases(SMs)to the lymph nodes in breast cancer,defined as discontiguous higher-level metastases in the absence of lower levels of contiguous metastases,have been reported in the contralateral cervical area of the primary tumor site in rare cases.CASE SUMMARY A 49-year-old previously healthy Chinese woman was diagnosed with right lateral invasive ductal carcinoma and underwent neoadjuvant chemotherapy treatment and bilateral mastectomy with axillary lymph node dissection.No malignancy of the left breast or axillary or distant metastases were identified preoperatively.However,enlarged left cervical lymph nodes were detected 36 mo after surgery,and rapidly enlarging thyroid glands without nodules were detected 42 mo after surgery.Fine-needle aspiration cytology was performed on the left cervical lymph nodes and left lobe of the thyroid,which were both revealed to contain metastases from the primary breast cancer.Additionally,the immunostaining profiles changed in the process of metastases.The patient was discharged with the NP(vinorelbine and cisplatin)regimen for subsequent treatment,and stable disease was determined when the curative effect was evaluated.CONCLUSION Diffuse goiter may be the first sign of TM,and enlarged lymph nodes in the contralateral cervical area may be SMs of primary breast cancer. 展开更多
关键词 Metastases to the thyroid gland Diffuse goiter Cervical lymph node recurrence Breast cancer Case report
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Blunt injury to the thyroid gland: A case of delayed surgical emergency 被引量:1
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作者 Geraud Galvaing Julien Brehant 《World Journal of Emergency Medicine》 CAS 2017年第3期231-232,共2页
Blunt trauma to the thyroid gland is a possibly life- threatening condition known for years. However, only few cases have been reported in the English-language literature, so that no consensus has emerged as to its wo... Blunt trauma to the thyroid gland is a possibly life- threatening condition known for years. However, only few cases have been reported in the English-language literature, so that no consensus has emerged as to its workup or management. 展开更多
关键词 Blunt injury the thyroid gland
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Colorectal cancer metastases to the thyroid gland:A case report 被引量:1
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作者 Patricia Ciriano Hernández Carlos Martínez Pinedo +7 位作者 Enrique Calcerrada Alises Esther García Santos Susana Sánchez García Rafael Picón Rodríguez Elisa Jiménez Higuera Daniel Sánchez Peláez Violeta Herrera Montoro esús Martín Fernández 《World Journal of Gastrointestinal Surgery》 2020年第3期116-122,共7页
BACKGROUND Secondary malignancies of the thyroid gland are a rare finding in clinical practice.In addition,colorectal metastasis to the thyroid(CMT)is even more infrequently diagnosed.The source of the primary tumor f... BACKGROUND Secondary malignancies of the thyroid gland are a rare finding in clinical practice.In addition,colorectal metastasis to the thyroid(CMT)is even more infrequently diagnosed.The source of the primary tumor follows demographic and ethnic patterns,which reflects the most prevalent malignancies in the different populations.Colorectal cancer is one of the most common types of cancer worldwide;nevertheless,CMT is infrequently diagnosed.Most of them are identified during the follow-up of gastrointestinal primary malignancies.Due to the improvement of image techniques,oncological treatment,and follow-up,survival and consequent diagnosis of metastatic disease are more frequent.Those facts make this entity a diagnostic and therapeutic challenge,due to the lack of information and the difficulties performing clinical trials and research.CASE SUMMARY Here,we present a case report of a patient diagnosed with CMT of adenocarcinoma of the rectum evidenced during follow-up,4 years after neoadjuvant chemoradiotherapy,who had subsequent curative surgical treatment of the primary tumor and inter-current lung bilateral metastases.CONCLUSION Thyroid metastases of extra-thyroid origin are an uncommon finding,even rarer in cases of CMT.The diagnostic process,as well as survival of oncologic patients is improving,and consequently the number of metastases to the thyroid gland is increasing. 展开更多
关键词 Colorectal cancer metastases Thyroid gland Case report Thyroid metastases
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Effects of Low Concentration Samarium Chloride on theUltrastructure and Function of Rat Thyroid Gland
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作者 周莉 黄可欣 +2 位作者 王晓辉 聂毓秀 朱秀雄 《Journal of Rare Earths》 SCIE EI CAS CSCD 1996年第2期150-153,共4页
The levels of thyroxine (T3, T4) and thyroid stimulating hormone (TSH) in rat serum were measured by radioimmunoassay, and also ultrastructure of the thyroid gland and adenohypophyseal cell were examined by transmissi... The levels of thyroxine (T3, T4) and thyroid stimulating hormone (TSH) in rat serum were measured by radioimmunoassay, and also ultrastructure of the thyroid gland and adenohypophyseal cell were examined by transmission electronic microscopy (TEM) after low concentration (0. 05 mg/kg) of samarium chloride (SmCl3) administration by intraperitoneal, oral and tail intravenous routes. The results showed that the level of T4 in rat serum increased and the level of TSH unchanged by the intraperitoneal administration, and the levels of T3, T4 and TSH did not increase by the oral and tail intravenous administration. The evidences mentioned above were in accord with the morphological changes of thyroid follicular epithelial cells andadenohypophysis thyrotroph observed under electronic microscope in a sense. 展开更多
关键词 Thyroid gland Adenohypophysis thyrotroph Samarium chloride Radioimmunoassay Ultrastructure
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Metastasis of esophageal squamous cell carcinoma to the thyroid gland with widespread nodal involvement: A case report
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作者 Xing Zhang Xin Gu +1 位作者 Jia-Gen Li Xian-Jie Hu 《World Journal of Clinical Cases》 SCIE 2020年第19期4588-4594,共7页
BACKGROUND Esophageal cancer is one of the most common causes of cancer-related death.Some patients with esophageal cancer have distant metastases at the time of diagnosis,but metastasis to the thyroid gland(MTG)and m... BACKGROUND Esophageal cancer is one of the most common causes of cancer-related death.Some patients with esophageal cancer have distant metastases at the time of diagnosis,but metastasis to the thyroid gland(MTG)and multifocal thyroid lesions alone are extremely rare.CASE SUMMARY In this case report,we present a case of a 69-year-old male with esophageal MTG.The patient visited our hospital for a routine body check-up,which revealed multifocal nodules in his thyroid lobes and enlarged cervical lymph nodes.A fine needle aspiration biopsy showed malignancies in both thyroid lesions and lymph nodes.The patient was initially diagnosed with primary bilateral thyroid cancer that spread to his lymph nodes,and a total thyroidectomy was performed.The histology showed MTG and therefore,a diagnostic work-up was implemented to determine the primary tumor.A fluorine-18-deoxyglucose positron emission tomography scan showed that the lower part of the esophagus and the lymph nodes in the neck,chest,and abdomen were involved.An esophagogastroscopy and corresponding pathology revealed distal esophageal squamous cell carcinoma.The esophageal MTG diagnosis was confirmed with pathological immunohistochemistry.CONCLUSION This case report highlights the difficulty in diagnosing esophageal MTG.Patients may have no malignancy history and be asymptomatic.Further diagnostic procedures are necessary after MTG is confirmed by cytology or histology,and the final diagnosis should be made according to the identification of the primary malignancy combined with pathological immunohistochemistry findings. 展开更多
关键词 Esophageal squamous cell carcinoma METASTASIS Thyroid gland THYROIDECTOMY Lymph nodes Case report
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A Case Report of Thyroid Gland Squamous Carcinoma with Multiple Metastases
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作者 Jing Zhao Guangyan Hu Lu Zhang Guoqing Hu 《Chinese Journal of Clinical Oncology》 CSCD 2007年第2期145-146,共2页
The patient was a female, 65 years to feel intermittent discomfort in old. Early in 1996, she began her neck, accompanied with hoarseness. In June, 2000, when she entered our hospital and accepted a physical examinati... The patient was a female, 65 years to feel intermittent discomfort in old. Early in 1996, she began her neck, accompanied with hoarseness. In June, 2000, when she entered our hospital and accepted a physical examination, we found a 3 cm×2 cm tumor at the lower pole of the thyroid gland. Neck CT showed that the mass was located at the inferiorposterior right part of the thyroid gland with a diffuse boundary. MRI showed that the right thyroid cartilage wall was incomplete. Fine-needle aspiration cytology indicated a suspected papillary tumor. 展开更多
关键词 thyroid gland cancer squamous carcinoma TREATMENT PROGNOSIS
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The Comparison of Entrance Surface Radiation Dose to the Thyroid Gland Region in Different Dental Panoramic Radiography
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作者 Siyambalagoda Gamage Manuja Dilan Yasiru Ibashini Nuwan Kumari Herath Bimali Sanjeevani Weerakoon 《Journal of Health Science》 2020年第3期83-86,共4页
Introduction:The proven radio sensitivity and the position of the thyroid gland make it a significant organ during the dental radiography exposure.Objectives:This study compared the surface radiation dose to the thyro... Introduction:The proven radio sensitivity and the position of the thyroid gland make it a significant organ during the dental radiography exposure.Objectives:This study compared the surface radiation dose to the thyroid gland region during two different techniques of two dimensional(2D)conventional orthopantomography(OPG)and three dimensional(3D)OPG reconstructed from cone beam computed tomography(CBCT).Methods:The entrance surface dose to the thyroid region of the patients was evaluated using a personal dosimeter in a sample of 156 patients who prescribed for an OPG examination.Results:The obtained mean dose values for conventional OPG and reconstructed OPG from CBCT are 7.47μSv and 28.65μSv,respectively.Further a significant difference(p<0.05)was observed between those two doses.Conclusions:A significant amount of dose reduction to the thyroid gland region can be obtained when using conventional OPG compared to the CBCT. 展开更多
关键词 ORTHOPANTOMOGRAPHY cone beam computed tomography thyroid gland region.
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Mobile Phone Use and Risk of Thyroid Gland Lesions Detected by Ultrasonography
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作者 Naglaa M. Elsayed Saddig D. Jastaniah 《Open Journal of Radiology》 2016年第2期140-146,共8页
In recent years, widespread use of mobile phones has led to a public debate about possible harmful effects on human health. A lot of researchers studied the possible effect of radiofrequency energy (RFE) emitted from ... In recent years, widespread use of mobile phones has led to a public debate about possible harmful effects on human health. A lot of researchers studied the possible effect of radiofrequency energy (RFE) emitted from cell phones on the human body. Up to our knowledge no one studied the effect of these waves on the thyroid gland by Ultrasonography (US). Our aim was to investigate the possible effects of EMR arising from cell phones on the thyroid gland using US. A prospective study was done on 180 participants, 110 females and 70 males, ranging in age from 15 to 65. A constructed questionnaire was distributed among them before performing US of the neck. Demographic data along with US findings were collected and statistically analyzed. A total of 46.7% of our participants had abnormal findings of the thyroid gland more in non smart phone users and more in females. The commonest abnormality was multinodular goiter (54%). Expanded researches are still needed to answer the question about the hazards of RFE on human health. All efforts should be made to encourage users of cellular phone to follow mobile device recommendations of manufacturers and avoid its possible hazards as possible. 展开更多
关键词 Radiofrequency Energy Mobile Phones ULTRASOUND Thyroid gland NODULES
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Factors influencing postoperative anxiety and depression following Iodine-131 treatment in patients with differentiated thyroid cancer:A cross-sectional study 被引量:4
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作者 Ying-Rui Su Xiao-Peng Yu +2 位作者 Li-Qun Huang Long Xie Jin-Shun Zha 《World Journal of Psychiatry》 SCIE 2023年第7期486-494,共9页
BACKGROUND Differentiated thyroid cancer(DTC)often seriously impacts patients’lives.Radionuclide Iodine-131(131I)is widely used in treating patients with DTC.However,most patients know little about radionuclide thera... BACKGROUND Differentiated thyroid cancer(DTC)often seriously impacts patients’lives.Radionuclide Iodine-131(131I)is widely used in treating patients with DTC.However,most patients know little about radionuclide therapy,and the treatment needs to be performed in a special isolation ward,which can cause anxiety and depression.AIM To explore anxiety and depression status and their influencing factors after 131I treatment in patients with DTC.METHODS A questionnaire survey was conducted among postoperative patients with DTC who received 131I treatment at our hospital from June 2020 to December 2022.General patient data were collected using a self-administered demographic characteristics questionnaire.The self-rating depression scale and self-rating anxiety scale were used to determine whether patients were worried about their symptoms and the degree of anxiety and depression.The patients were categorized into anxiety,non-anxiety,depression,and non-depression groups.Singlevariable and multiple-variable analyses were used to determine the risk factors for anxiety and depression in patients with thyroid cancer after surgery.RESULTS A total of 144 patients were included in this study.The baseline mean score of self-rating anxiety and depression scales were 50.06±16.10 and 50.96±16.55,respectively.Notably,48.62%(70/144)had anxiety and 47.22%(68/144)of the patients had depression.Sex,age,education level,marital status,household income,underlying diseases,and medication compliance significantly differed among groups(P<0.05).Furthermore,multivariate logistic regression analysis showed that education level,per capita monthly household income,and medication compliance level affected anxiety(P=0.015,0.001,and 0.001 respectively).Patient’s sex,marital status,and underlying diseases affected depression(P=0.007,0.001,and 0.009,respectively).CONCLUSION Nursing interventions aiming at reducing the risk of anxiety and depression should target unmarried female patients with low education level,low family income,underlying diseases,and poor adherence to medications. 展开更多
关键词 IODINE-131 Thyroid gland NEOPLASMS ANXIETY DEPRESSION PROGNOSIS
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Gastric autoimmune disorders in patients with chronic hepatitis C before,during and after interferon-alpha therapy 被引量:3
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作者 Carlo Fabbri M.Francesca Jaboli +11 位作者 Silvia Giovanelli Francesco Azzaroli Alessandro Pezzoli Esterita Accogli Stefania Liva Giovanni Nigro Anna Miracolo Davide Festi Antonio Colecchia Marco Montagnani Enrico Roda Giuseppe Mazzella 《World Journal of Gastroenterology》 SCIE CAS CSCD 2003年第7期1487-1490,共4页
AIM:To explore the prevalence of autoimmune gastritis in chronic hepatitis C virus (HCV) patients and the influence of α-interferon (IFN) treatment on autoimmune gastritis. METHODS:We performed a prospective study on... AIM:To explore the prevalence of autoimmune gastritis in chronic hepatitis C virus (HCV) patients and the influence of α-interferon (IFN) treatment on autoimmune gastritis. METHODS:We performed a prospective study on 189 patients with positive anti-HCV and viral RNA enrolled in a 12-month IFN protocol.We evaluated:a) the baseline prevalence of autoimmune gastritis,b) the impact of IFN treatment on development of biochemical signs of autoimmune gastritis (at 3,6 and 12 months),c) the evolution after IFN withdrawal (12 months) in terms of anti-gastric-parietal-cell antibodies (APCA),gastrin,anti-thyroid,and anti-non-organ- specific antibodies. RESULTS:APCA positivity and 3-fold gastrin levels were detected in 3 (1.6%) and 9 (5%) patients,respectively,at baseline,in 25 (13%) and 31 (16%) patients at the end of treatment (both P<0.001,vs baseline),and in 7 (4%) and 14 (7%) patients 12 months after withdrawal (P=0.002 and P=0.01 respectively,vs baseline;P=not significant vs end of treatment).The development of autoimmune gastritis was strictly associated with the presence of autoimmune thyroiditis (P=0.0001),no relationship was found with other markers of autoimmunity. CONCLUSION:In HCV patients,IFN frequently precipitates latent autoimmune gastritis,particularly in females.Following our 12-month protocol,the phenomenon generally regressed.Since APCA positivity and high gastrin levels are associated with the presence of antithyroid antibodies, development of autoimmune thyroiditis during IFN treatment may provide a surrogate preliminary indicator of possible autoimmune gastritis to limit the need for invasive examinations. 展开更多
关键词 Adult Aged Antiviral Agents DOSAGE Autoimmune Diseases Female GASTRINS GASTRITIS Helicobacter Infections Helicobacter pylori Hepatitis C Chronic Humans INTERFERON-ALPHA Male Middle Aged Organ Specificity Parietal Cells Gastric Prevalence Prospective Studies Thyroid gland Treatment Outcome
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EFFECTS OF ACUPUNCTURE ON THE PITUITARYTHYROID AXIS IN RABBITS WITH FRACTURE 被引量:1
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作者 沈梅红 祁晓华 +3 位作者 黄晔 吕越 蔡文辉 王友京 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1999年第4期300-303,共4页
PURPOSE: To observe the effects of acupuncture on the pituitary-thyroid axis in rabbits with fracture. METHOD: 36 male rabbits with a 3-mm width experimental defect in the middle segment of the left radius were random... PURPOSE: To observe the effects of acupuncture on the pituitary-thyroid axis in rabbits with fracture. METHOD: 36 male rabbits with a 3-mm width experimental defect in the middle segment of the left radius were randomly divided into the treatment group and control group, and the changes in serum T3, T4 and TSH contents in different weeks were investigated. RESULTS: Serum T3, T4 and TSH contents in the treatment group all were higher than those in the control group, with statistically significant differences in the contents of T4 and TSH in the second week and T3 content in the fourth week (P 展开更多
关键词 ELECTROACUPUNCTURE Animals Hypothalamo-Hypophyseal System Male RABBITS Radius Fractures Random Allocation Thyroid gland THYROTROPIN THYROXINE TRIIODOTHYRONINE
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Rare primary mature teratoma of the liver:A case report 被引量:1
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作者 Yury A Kovalenko Yury O Zharikov +5 位作者 Yana V Kiseleva Anton B Goncharov Tatyana V Shevchenko Beslan N Gurmikov Dmitry V Kalinin Alexey V Zhao 《World Journal of Hepatology》 2021年第12期2192-2200,共9页
BACKGROUND Primary liver teratoma is an extremely rare tumor usually affecting children under the age of 3 years.Specific signs of teratoma on ultrasound,computed tomography(CT)or magnetic resonance imaging are lackin... BACKGROUND Primary liver teratoma is an extremely rare tumor usually affecting children under the age of 3 years.Specific signs of teratoma on ultrasound,computed tomography(CT)or magnetic resonance imaging are lacking,which makes morphology the only diagnostic tool.Misdiagnosis of a mature teratoma may lead to excessive liver resection,whereas misdiagnosis of an immature teratoma may result in spread,causing a life-threatening condition.Consequently,a careful tumor examination is important,and the rarest types of tumors must be accounted for.CASE SUMMARY We describe a 52 years old female who presented with a solid mass in the left liver lobe.Contrast-enhanced CT and magnetic resonance imaging(MRI)revealed a round,heterogeneous lesion containing a number of fluid areas and areas of calcification in the middle,and the provisional diagnosis was cholangiocarcinoma.The patient underwent resection of liver segment I.Immunohistochemistry analysis of the resected lesion indicated thyroid follicular epithelium;however,the thyroid gland was intact.10 years prior to presentation the patient underwent a surgery due to mature teratoma of the right ovary,nevertheless the tumor was benign and could not spread to the liver,in addition teratoma of the liver was also benign.This led to the final diagnosis of primary mature liver teratoma.CONCLUSION Primary hepatic teratoma,including heterotopia of the thyroid gland in the liver,is an extremely rare condition in adults that needs to be considered in the differential diagnosis of solid-cystic neoplasms in the liver and cholangiocarcinoma.This case adds to the limited literature on the patient presentation,clinical workup and management of liver teratomas. 展开更多
关键词 Case report Primary liver teratoma Ectopic thyroid gland tissue Mature teratoma Epidermoi cyst
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THE EFFECT OF FCγ RECEPTOR ON THE PATHOGENESIS OF GRAVES' DISEASE
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作者 蒲丹 郭辉 +2 位作者 雒文田 刘秋月 Aosai Fumie 《Journal of Pharmaceutical Analysis》 SCIE CAS 2004年第2期190-192,共3页
Objective To explore the roles of Fcγ recep tor in the pathogenesis of Graves' disease. Methods Fcγ receptor gene knockout mice(Fcγ R KO m ice) which were rooted in C57BL/6 mice and wild type C57BL/6 mice wer... Objective To explore the roles of Fcγ recep tor in the pathogenesis of Graves' disease. Methods Fcγ receptor gene knockout mice(Fcγ R KO m ice) which were rooted in C57BL/6 mice and wild type C57BL/6 mice were immunized by hTSH receptor expressing cells (DAP3.WT). 1-2×107 DAP3.WT cells were peri toneally injected into mice every two weeks for a total of six times. Two weeks after final immunization, mice were killed for measurement of total thyroxine, T RAb and pathological examination. Results The thyroxine level of the immunized Fcγ recept or gene knockout mice was significantly lower than that of the immunized wild ty pe control mice (2.2±0.31 vs. 3.32± 0.59 g·dL -1, P< 0.05 ),but there was no significant difference between immunized Fcγ R KO mic e and non-immunized wild type control group. The TRAb levels of the immunized F γ R KO mice significantly increased compared to those of the immunized wild type mice (21.75±8.21 vs. 14.11±6.21, P< 0.05). The lymphocyte cel ls infiltration and destruction of thyroid follicles were found in the thyroid gland of the immunized Fcγ R KO mice. Conclusion These results suggest that Fcγ receptor may be involved in the pathogenesis of Graves' disease. 展开更多
关键词 Graves' disease Fcγ receptor gene knockou t thyroid gland
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Metastasis of liver cancer to the thyroid after surgery:A case report
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作者 Hao-Chen Zhong Zhao-Wei Sun +4 位作者 Guang-Hua Cao Wei Zhao Kai Ma Bing-Yuan Zhang Yu-Jie Feng 《World Journal of Clinical Cases》 SCIE 2022年第15期5036-5041,共6页
BACKGROUND Secondary thyroid malignancies are rarely reported,especially thyroid metastasis after resection of hepatocellular carcinoma(HCC).We report a patient with thyroid metastasis after resection of HCC.CASE SUMM... BACKGROUND Secondary thyroid malignancies are rarely reported,especially thyroid metastasis after resection of hepatocellular carcinoma(HCC).We report a patient with thyroid metastasis after resection of HCC.CASE SUMMARY A 42-year-old female underwent partial hepatectomy for HCC three years ago.She attended hospital because of neck discomfort.After various examinations,she was diagnosed with metastatic HCC.She survived after surgical resection of the affected side of the thyroid.CONCLUSION Although secondary malignant tumor of the thyroid is classified as distant metastasis,surgical resection is still necessary according to the patient's condition. 展开更多
关键词 Hepatocellular carcinoma Liver cancer Thyroid gland METASTASIS SURGERY Case report
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Laboratory Findings in Twins Suffering from Autism—Case Report
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作者 Slobodan Dunjic Jovana Pejic +5 位作者 Emilija Filipovic Milos Maletic Petar Krakovic Dana Stojicic Milica Lojic Vida Subotic 《Journal of Health Science》 2019年第4期239-245,共7页
Autism refers a wide range of conditions and the most prominent are challenges with social skills, repetitive behaviors, speech disturbances. By now, it is known that there is no one type of autism, but there are many... Autism refers a wide range of conditions and the most prominent are challenges with social skills, repetitive behaviors, speech disturbances. By now, it is known that there is no one type of autism, but there are many of them which are caused by genetic factors and environmental influences. Sometimes autism is called autism spectrum disorders which reflect the wide variation in challenges and strengths possessed by each person with autism (e.g., gastrointestinal disorders, seizures, sleep disturbances, attention deficit and hyperactivity disorders, anxiety etc.). Around one third of all people with autism remain nonverbal and have an intellectual disability. This condition can be detected as early as 18 months, but the most obvious signs tend to appear between 2 and 3 years of age. Only early intervention in those patients can improve outcomes. There are no many articles published regarding laboratory findings in autism patients. By performing holistic approach in patient healing, we also face autistic children in everyday practice. In this paper we represented case of twins suffering from autism. We found that both of them had elevation of free triiodothyronine, oxytocin, osteocalcin, and basophils. We found that vitamin D level in both twins was lower than recommended. Further research in this field is necessary to reveal whether these findings are causal factors for autism or are an effect of the disease. 展开更多
关键词 AUTISM OSTEOCALCIN thyroid gland vitamin D OXYTOCIN
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Hypothyroidism in Childhood and Adolescence
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作者 Deise Dutra Terra Carvalho Denise Rosso Tenório Wanderley Rocha Alberto Krayyem Arbex 《Open Journal of Endocrine and Metabolic Diseases》 2016年第1期72-77,共6页
Juvenile hypothyroidism is an unfrequent form of hypothyroidism that affects children. If not diagnosed and treated properly, it may cause severe neurological disorders during growth. The most frequent difficulties ar... Juvenile hypothyroidism is an unfrequent form of hypothyroidism that affects children. If not diagnosed and treated properly, it may cause severe neurological disorders during growth. The most frequent difficulties are found in school performance, difficulties in concentration, hyperactivity or fatigue and damage on the onset of puberty. Starting levothyroxine as a drug of choice is essential, and it should be made according to the age and weight of the child. Laboratory tests for control should be requested periodically, along with a strict control of the child’s development and growth. The family-doctor relationship, along with a clear guidance on the importance of treatment, is critical to achieve a successful treatment. This article is a review about the main clinical features of hypothyroidism in childhood, especially in developing countries, providing key aspects of adherence and characteristics of its follow-up. 展开更多
关键词 Thyroid gland Neonatal Screening HYPOTHYROIDISM Congenital Hypothyroidism Juvenile Hypothyroidism LEVOTHYROXINE
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Graves’ Disease and Down Syndrome: Case Report
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作者 Fábio Ferreira do Espírito Santo Denise Rosso Tenório Wanderley Rocha Alberto Krayyem Arbex 《Open Journal of Endocrine and Metabolic Diseases》 2016年第1期20-27,共8页
Down syndrome (DS) is the most common chromosomal abnormality in humans, and the most frequent cause of mental retardation. Patients affected by this syndrome show an increased prevalence of autoimmune diseases. The m... Down syndrome (DS) is the most common chromosomal abnormality in humans, and the most frequent cause of mental retardation. Patients affected by this syndrome show an increased prevalence of autoimmune diseases. The most common of those is Hypothyroidism. We present a case report describing the association of Down syndrome with Hyperthyroidism. An 18-year-old patient presented with a history of recurrent throat infections and intermittent diarrhea, having developed a total alopecia areata within one month from the first visit to the physician. After consultations with general practitioners, he was directed to an Endocrinology Ambulatory and diagnosed with a clear case of Graves’ disease associated with Down syndrome. Treatment was started with methimazole 20 mg/day, and after two months, was adjusted to 40 mg/day. The patient reached adequate clinical and laboratory balance after five months of treatment. Thus, the association between Down syndrome and Graves’ Disease is relevant in medical practice, due to its specific characteristics on diagnosis, and the need of an adequate treatment regarding this disease association. 展开更多
关键词 Down Syndrome Graves’ Disease Alopecia Areata METHIMAZOLE Thyroid gland
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