Tunnel boring machines(TBMs)have been widely utilised in tunnel construction due to their high efficiency and reliability.Accurately predicting TBM performance can improve project time management,cost control,and risk...Tunnel boring machines(TBMs)have been widely utilised in tunnel construction due to their high efficiency and reliability.Accurately predicting TBM performance can improve project time management,cost control,and risk management.This study aims to use deep learning to develop real-time models for predicting the penetration rate(PR).The models are built using data from the Changsha metro project,and their performances are evaluated using unseen data from the Zhengzhou Metro project.In one-step forecast,the predicted penetration rate follows the trend of the measured penetration rate in both training and testing.The autoregressive integrated moving average(ARIMA)model is compared with the recurrent neural network(RNN)model.The results show that univariate models,which only consider historical penetration rate itself,perform better than multivariate models that take into account multiple geological and operational parameters(GEO and OP).Next,an RNN variant combining time series of penetration rate with the last-step geological and operational parameters is developed,and it performs better than other models.A sensitivity analysis shows that the penetration rate is the most important parameter,while other parameters have a smaller impact on time series forecasting.It is also found that smoothed data are easier to predict with high accuracy.Nevertheless,over-simplified data can lose real characteristics in time series.In conclusion,the RNN variant can accurately predict the next-step penetration rate,and data smoothing is crucial in time series forecasting.This study provides practical guidance for TBM performance forecasting in practical engineering.展开更多
Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher morbidity.Nevertheless,the optimal operative time range remains uncertain.This study aimed to estimate the id...Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher morbidity.Nevertheless,the optimal operative time range remains uncertain.This study aimed to estimate the ideal operative time range and evaluate its applicability in laparoscopic cancer surgery.Methods:A prospectively collected multicenter database of 397 patients who underwent laparoscopic distal gastrectomy were retrospectively reviewed.The ideal operative time range was statistically calculated by separately analyzing the operative time of uneventful surgeries.Finally,intraoperative and postoperative outcomes were compared among the shorter,ideal,and longer operative time groups.Results:The statistically calculated ideal operative time was 135.4-165.4 min.The longer operative time(LOT)group had a lower rate of uneventful,perfect surgery than the ideal or shorter operative time(IOT/SOT)group(2.8%vs.8.8%and 2.2%vs.13.4%,all P<0.05).Longer operative time increased bleeding,postoperative morbidities,and delayed diet and discharge(all P<0.05).Particularly,an uneventful,perfect surgery could not be achieved when the operative time exceeded 240 min.Regardless of ideal time range,SOT group achieved the highest percentage of uneventful surgery(13.4%),which was possible by surgeon's ability to retrieve a higher number of lymph nodes and perform≥150 gastrectomies annually.Conclusions:Operative time longer than the ideal time range(especially≥240 min)should be avoided.If the essential operative procedure were faithfully conducted without compromising oncological safety,an operative time shorter than the ideal range leaded to a better prognosis.Efforts to minimize operative time should be attempted with sufficient surgical experience.展开更多
Train timetables and operations are defined by the train running time in sections,dwell time at stations,and headways between trains.Accurate estimation of these factors is essential to decision-making for train delay...Train timetables and operations are defined by the train running time in sections,dwell time at stations,and headways between trains.Accurate estimation of these factors is essential to decision-making for train delay reduction,train dispatching,and station capacity estimation.In the present study,we aim to propose a train dwell time model based on an averaging mechanism and dynamic updating to address the challenges in the train dwell time prediction problem(e.g.,dynamics over time,heavy-tailed distribution of data,and spatiotemporal relationships of factors)for real-time train dispatching.The averaging mechanism in the present study is based on multiple state-of-the-art base predictors,enabling the proposed model to integrate the advantages of the base predictors in addressing the challenges in terms of data attributes and data distributions.Then,considering the influence of passenger flow on train dwell time,we use a dynamic updating method based on exponential smoothing to improve the performance of the proposed method by considering the real-time passenger amount fluctuations(e.g.,passenger soars in peak hours or passenger plunges during regular periods).We conduct experiments with the train operation data and passenger flow data from the Chinese high-speed railway line.The results show that due to the advantages over the base predictors,the averaging mechanism can more accurately predict the dwell time at stations than its counterparts for different prediction horizons regarding predictive errors and variances.Further,the experimental results show that dynamic smoothing can significantly improve the accuracy of the proposed model during passenger amount changes,i.e.,15.4%and 15.5%corresponding to the mean absolute error and root mean square error,respectively.Based on the proposed predictor,a feature importance analysis shows that the planned dwell time and arrival delay are the two most important factors to dwell time.However,planned time has positive influences,whereas arrival delay has negative influences.展开更多
Left main (LM) stenting is considered by many to be one of the last frontiers of interventional cardiology. Beginning with the VA cooperative study published in 1976 demonstrating a mortality benefit for patients ... Left main (LM) stenting is considered by many to be one of the last frontiers of interventional cardiology. Beginning with the VA cooperative study published in 1976 demonstrating a mortality benefit for patients undergoing coronary artery bypass grafting (CABG), i the standard of care for treatment of left main coronary artery disease has been surgical.The most recent 2005 update of the ACC/AHA/SCAI Practice Guidelines on PCI 2 again notes that "CABG using IMA grafting is the 'gold standard' for treatment of unprotected left main disease and has proven benefit on long-term outcomes."……展开更多
Perinatal brain injury(PBI)is one of the most important causes of lifelong deficits in cognition,behavior,social interaction and motor skills,as well as epilepsy.PBI encompasses,but is not limited to,hypoxic-ischemi...Perinatal brain injury(PBI)is one of the most important causes of lifelong deficits in cognition,behavior,social interaction and motor skills,as well as epilepsy.PBI encompasses,but is not limited to,hypoxic-ischemic encephalopathy(HIE),intraventricular hemorrhage,periventricular leukomalacia and encephalopathy of prematurity.展开更多
To improve the forecasting reliability of travel time, the time-varying confidence interval of travel time on arterials is forecasted using an autoregressive integrated moving average and generalized autoregressive co...To improve the forecasting reliability of travel time, the time-varying confidence interval of travel time on arterials is forecasted using an autoregressive integrated moving average and generalized autoregressive conditional heteroskedasticity (ARIMA-GARCH) model. In which, the ARIMA model is used as the mean equation of the GARCH model to model the travel time levels and the GARCH model is used to model the conditional variances of travel time. The proposed method is validated and evaluated using actual traffic flow data collected from the traffic monitoring system of Kunshan city. The evaluation results show that, compared with the conventional ARIMA model, the proposed model cannot significantly improve the forecasting performance of travel time levels but has advantage in travel time volatility forecasting. The proposed model can well capture the travel time heteroskedasticity and forecast the time-varying confidence intervals of travel time which can better reflect the volatility of observed travel times than the fixed confidence interval provided by the ARIMA model.展开更多
History proves that some countries and regions benefited from international industry transfer, because of international industrial transfer can stimulate their economic growth.Thanks to the manufacturing transfer impl...History proves that some countries and regions benefited from international industry transfer, because of international industrial transfer can stimulate their economic growth.Thanks to the manufacturing transfer implemented by EU, USA, Japan and some Asian developed countries in 1980s, China’s economic situation has boomed over 30 years. Textile industry as a traditional industry in China has its own competitive advantage. It can be confirmed that textile industry will play an important role during the fourth Industry transfer period. So, who will be the winner this time?展开更多
Panzhihua, in south Sichuan’s basin, is aptly called West China’s Industrial Pearl, and "treasure bowl." This city is well known as the home of Panzhihua Iron and Steel Group Company and Ertan Hydropower S...Panzhihua, in south Sichuan’s basin, is aptly called West China’s Industrial Pearl, and "treasure bowl." This city is well known as the home of Panzhihua Iron and Steel Group Company and Ertan Hydropower Station. At the beginning of 2004, two major events thrust this city into the limelight.展开更多
FOR the first time In its 16-year existence, the Milken Institute Global Conference 2013 in Los Angeles included four panels devoted to discussing African opportunities and challenges. A decade ago, perceptions of Afr...FOR the first time In its 16-year existence, the Milken Institute Global Conference 2013 in Los Angeles included four panels devoted to discussing African opportunities and challenges. A decade ago, perceptions of Africa were extremely negative. The May 2000 cover of a major international publication described Africa as “The Hopeless Continent.” Fast forward to 2011, and the same magazine ran a more optimistic headline: "Africa Rising." There is a media frenzy focused on Africa and the continent's gains are tangible.展开更多
While China's tea consumption slows,globally tea lovers are sipping with increasing zest WHEN you think of China one of the first things that comes to mind is tea.It is a staple beverage intrinsically woven into the ...While China's tea consumption slows,globally tea lovers are sipping with increasing zest WHEN you think of China one of the first things that comes to mind is tea.It is a staple beverage intrinsically woven into the tapestry of Chinese lifestyle in a country that has the earliest records of tea drinking.China today shares its展开更多
THE first thing Cai Banghong does every morning is to look at the sales figure of various tea brands on his online store. Hmongling Tea Garden, before posting promotional information and collecting customers' feed- b...THE first thing Cai Banghong does every morning is to look at the sales figure of various tea brands on his online store. Hmongling Tea Garden, before posting promotional information and collecting customers' feed- back to help target his products Cai spent two decades growing his tea company from a small backroom operation into a modern tea company integrating planting, processing and sales.展开更多
To determine the optimal time for harvesting the seeds of Gui 39722, which is the female parent of a newly-developed maize hybrid Guidan 0810, the cobs of Gui 39722 were harvested 31 (the first stage), 34 (the seco...To determine the optimal time for harvesting the seeds of Gui 39722, which is the female parent of a newly-developed maize hybrid Guidan 0810, the cobs of Gui 39722 were harvested 31 (the first stage), 34 (the second stage), 37 (the third stage), 40 (the fourth stage), 43 (the fifth stage) and 46 (the sixth stage) d after pollination and oven dried at 38 ~C to constant weight. Then, the 1 000-ker- nel weight, germination rate and the agronomic traits of three-leaf seedlings were measured and compared. The results showed that the seeds of Gui 39722 harvest- ed 43 d after pollination (the fifth stage) had the greatest germination rate, seedling height, vigor index, root dry weight, shoot dry weight and germination potential, and high 1 000-kernel weight (very close to the highest level), root length, number of roots per seedling and root-shoot ratio. Therefore, 43 d after pollination was the op- timal time for harvesting the seeds of Gui 39722, when the effective accumulated temperature after pollination reached 780.7 ℃ and the ear leaf dried. The seeds harvested at this stage had the highest yield and the best quality. Field sampling revealed that 89.00% to 95.00% (with an average of 91.15%) of the seedlings of six stages of seeds grew well.展开更多
AIM:To identify the determinants of endoscopic submucosal dissection(ESD) operation time.METHODS:This investigation was conducted as a single-center,prospective study in which ESD was performed by the same endoscopist...AIM:To identify the determinants of endoscopic submucosal dissection(ESD) operation time.METHODS:This investigation was conducted as a single-center,prospective study in which ESD was performed by the same endoscopist at the Chinese PLA General Hospital.A total of 173 patients underwent ESD operations performed by Dr.Lu from July 2007 to December 2011,and 183 lesions were enrolled.Patient gender,age,tumor location,gross type,tumor size,pathological type and adhesions were recorded prospectively.The order of treatment represented the experience of the operator.Univariate analysis and multivariate analysis were performed to evaluate the relationships between these factors and ESD procedure time.RESULTS:Univariate analysis showed the ESD time was closely related to the gender(P = 0.0210),tumor size(P < 0.0001),location(P < 0.0001),gross type(P < 0.0001) and adhesion(P = 0.0010).The surgical proficiency level was associated with ESD time in unit area(P < 0.0001).Multivariate analysis revealed that the ESD time was positively correlated with tumor size(P < 0.0001),adhesion(P < 0.0001) and location(P < 0.0001),but negatively correlated with surgical proficiency level(P = 0.0046).CONCLUSION:Large tumor size,adjacency to the cardia,and adhesion are predictors of a long ESD time,whereas high surgical proficiency level predicts a short ESD time.展开更多
While emergency medical service (EMS) response time (ERT) is a major factor associated with the survival of patients with cardiovascular disease (CVD), relatively few studies have explored the factors associated with ...While emergency medical service (EMS) response time (ERT) is a major factor associated with the survival of patients with cardiovascular disease (CVD), relatively few studies have explored the factors associated with ERT. This study aimed to assess the current status of ERT and to identify the factors affecting ERT in patients with CVD in China. Between January 1, 2011 and December 31, 2015, EMS responses to CVD incidents in Guangzhou, China, were examined. The primary outcome was ERT, defined as the time from receipt of an emergency call to the arrival of paramedics on the scene. Factors associated with ERT were evaluated by multivariable logistic regression. A total of 44 383 CVD incidents were analysed. The median ERT was 12.58 min (interquartile range=9.98-15.67). Among the risk factors, distance (OR=13.73, 95% CI=11.76- 16.04), level of hospital (OR=1.57, 95% CI=1.40-1.75), and site of the incident (OR=1.53, 95% CI=1.38-1.69) were the top three significant factors affecting the ERT. Our results suggest that greater attention should be given to factors affecting the ERT. It is essential to make continuous efforts to promote the development of effective interventions to reduce the response time.展开更多
This paper will investigate global exponential stability analysis for a class of switched positive nonlinear systems under minimum dwell time switching, whose nonlinear functions for each subsystem are constrained in ...This paper will investigate global exponential stability analysis for a class of switched positive nonlinear systems under minimum dwell time switching, whose nonlinear functions for each subsystem are constrained in a sector field by two odd symmetric piecewise linear functions and whose system matrices for each subsystem are Metzler. A class of multiple time-varying Lyapunov functions is constructed to obtain the computable sufficient conditions on the stability of such switched nonlinear systems within the framework of minimum dwell time switching.All present conditions can be solved by linear/nonlinear programming techniques. An example is provided to demonstrate the effectiveness of the proposed result.展开更多
Referring to the 1 248 survey data of rural population in 14 provinces of China, the influencing factors of trip time choice were analyzed. Based on the basic theory of disaggregate model and its modelling method, nin...Referring to the 1 248 survey data of rural population in 14 provinces of China, the influencing factors of trip time choice were analyzed. Based on the basic theory of disaggregate model and its modelling method, nine grades were selected as the alternatives of trip time, the variables affecting time choice and the method getting their values were determined, and a multinomial logit (MNL) model was developed. Another 1 200 trip data of rural population were selected to testify the model's validity. The result shows that the maximum absolute error of each period between calculated value and statistic is 3.6%, so MNL model has high calculation accuracy.展开更多
This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutive...This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutively expressing enhanced green fluorescence protein, or media alone, were injected into the subarachnoid space of adult rats at 1 hour (acute stage), 7 days (subacute stage) and 28 days (chronic stage) after contusive spinal cord injury. Results showed that grafted neural progenitor cells migrated and aggregated around the blood vessels of the injured region, and infiltrated the spinal cord parenchyma along the tissue spaces in the acute stage transplantation group. However, this was not observed in subacute and chronic stage transplantation groups. 04- and glial fibrillary acidic protein-positive cells, representing oligodendrocytes and astrocytes respectively, were detected in the core of the grafted cluster attached to the cauda equina pia surface in the chronic stage transplantation group 8 weeks after transplantation. Both acute and subacute stage transplantation groups were negative for 04 and glial fibrillary acidic protein cells. Basso, Beattie and Bresnahan scale score comparisons indicated that rat hind limb locomotor activity showed better recovery after acute stage transplantation than after subacute and chronic transplantation. Our experimental findings suggest that the subarachnoid route could be useful for transplantation of neural progenitor cells at the acute stage of spinal cord injury. Although grafted cells survived only for a short time and did not differentiate into astrocytes or neurons, they were able to reach the parenchyma of the injured spinal cord and improve neurological function in rats. Transplantation efficacy was enhanced at the acute stage in comparison with subacute and chronic stages.展开更多
This paper proposes a multivariable fixed-time leaderfollower formation control method for a group of nonholonomic mobile robots, which has the ability to estimate multiple uncertainties. Firstly, based on the state s...This paper proposes a multivariable fixed-time leaderfollower formation control method for a group of nonholonomic mobile robots, which has the ability to estimate multiple uncertainties. Firstly, based on the state space model of the leader-follower formation, a multivariable fixed-time formation kinematics controller is designed. Secondly, to overcome uncertainties existing in the nonholonomic mobile robot system, such as load change,friction, external disturbance, a multivariable fixed-time torque controller based on the fixed-time disturbance observer at the dynamic level is designed. The designed torque controller is cascaded with the formation controller and finally realizes accurate estimation of the uncertain part of the system, the follower tracking of reference velocity and the desired formation of the leader and the follower in a fixed-time. The fixed-time upper bound is completely determined by the controller parameters, which is independent of the initial state of the system. The multivariable fixed-time control theory and the Lyapunov method are adopted to ensure the system stability.Finally, the effectiveness of the proposed algorithm is verified by the experimental simulation.展开更多
文摘Tunnel boring machines(TBMs)have been widely utilised in tunnel construction due to their high efficiency and reliability.Accurately predicting TBM performance can improve project time management,cost control,and risk management.This study aims to use deep learning to develop real-time models for predicting the penetration rate(PR).The models are built using data from the Changsha metro project,and their performances are evaluated using unseen data from the Zhengzhou Metro project.In one-step forecast,the predicted penetration rate follows the trend of the measured penetration rate in both training and testing.The autoregressive integrated moving average(ARIMA)model is compared with the recurrent neural network(RNN)model.The results show that univariate models,which only consider historical penetration rate itself,perform better than multivariate models that take into account multiple geological and operational parameters(GEO and OP).Next,an RNN variant combining time series of penetration rate with the last-step geological and operational parameters is developed,and it performs better than other models.A sensitivity analysis shows that the penetration rate is the most important parameter,while other parameters have a smaller impact on time series forecasting.It is also found that smoothed data are easier to predict with high accuracy.Nevertheless,over-simplified data can lose real characteristics in time series.In conclusion,the RNN variant can accurately predict the next-step penetration rate,and data smoothing is crucial in time series forecasting.This study provides practical guidance for TBM performance forecasting in practical engineering.
文摘Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher morbidity.Nevertheless,the optimal operative time range remains uncertain.This study aimed to estimate the ideal operative time range and evaluate its applicability in laparoscopic cancer surgery.Methods:A prospectively collected multicenter database of 397 patients who underwent laparoscopic distal gastrectomy were retrospectively reviewed.The ideal operative time range was statistically calculated by separately analyzing the operative time of uneventful surgeries.Finally,intraoperative and postoperative outcomes were compared among the shorter,ideal,and longer operative time groups.Results:The statistically calculated ideal operative time was 135.4-165.4 min.The longer operative time(LOT)group had a lower rate of uneventful,perfect surgery than the ideal or shorter operative time(IOT/SOT)group(2.8%vs.8.8%and 2.2%vs.13.4%,all P<0.05).Longer operative time increased bleeding,postoperative morbidities,and delayed diet and discharge(all P<0.05).Particularly,an uneventful,perfect surgery could not be achieved when the operative time exceeded 240 min.Regardless of ideal time range,SOT group achieved the highest percentage of uneventful surgery(13.4%),which was possible by surgeon's ability to retrieve a higher number of lymph nodes and perform≥150 gastrectomies annually.Conclusions:Operative time longer than the ideal time range(especially≥240 min)should be avoided.If the essential operative procedure were faithfully conducted without compromising oncological safety,an operative time shorter than the ideal range leaded to a better prognosis.Efforts to minimize operative time should be attempted with sufficient surgical experience.
基金This work was supported by the National Natural Science Foundation of China(No.71871188).
文摘Train timetables and operations are defined by the train running time in sections,dwell time at stations,and headways between trains.Accurate estimation of these factors is essential to decision-making for train delay reduction,train dispatching,and station capacity estimation.In the present study,we aim to propose a train dwell time model based on an averaging mechanism and dynamic updating to address the challenges in the train dwell time prediction problem(e.g.,dynamics over time,heavy-tailed distribution of data,and spatiotemporal relationships of factors)for real-time train dispatching.The averaging mechanism in the present study is based on multiple state-of-the-art base predictors,enabling the proposed model to integrate the advantages of the base predictors in addressing the challenges in terms of data attributes and data distributions.Then,considering the influence of passenger flow on train dwell time,we use a dynamic updating method based on exponential smoothing to improve the performance of the proposed method by considering the real-time passenger amount fluctuations(e.g.,passenger soars in peak hours or passenger plunges during regular periods).We conduct experiments with the train operation data and passenger flow data from the Chinese high-speed railway line.The results show that due to the advantages over the base predictors,the averaging mechanism can more accurately predict the dwell time at stations than its counterparts for different prediction horizons regarding predictive errors and variances.Further,the experimental results show that dynamic smoothing can significantly improve the accuracy of the proposed model during passenger amount changes,i.e.,15.4%and 15.5%corresponding to the mean absolute error and root mean square error,respectively.Based on the proposed predictor,a feature importance analysis shows that the planned dwell time and arrival delay are the two most important factors to dwell time.However,planned time has positive influences,whereas arrival delay has negative influences.
文摘 Left main (LM) stenting is considered by many to be one of the last frontiers of interventional cardiology. Beginning with the VA cooperative study published in 1976 demonstrating a mortality benefit for patients undergoing coronary artery bypass grafting (CABG), i the standard of care for treatment of left main coronary artery disease has been surgical.The most recent 2005 update of the ACC/AHA/SCAI Practice Guidelines on PCI 2 again notes that "CABG using IMA grafting is the 'gold standard' for treatment of unprotected left main disease and has proven benefit on long-term outcomes."……
文摘Perinatal brain injury(PBI)is one of the most important causes of lifelong deficits in cognition,behavior,social interaction and motor skills,as well as epilepsy.PBI encompasses,but is not limited to,hypoxic-ischemic encephalopathy(HIE),intraventricular hemorrhage,periventricular leukomalacia and encephalopathy of prematurity.
基金The National Natural Science Foundation of China(No.51108079)
文摘To improve the forecasting reliability of travel time, the time-varying confidence interval of travel time on arterials is forecasted using an autoregressive integrated moving average and generalized autoregressive conditional heteroskedasticity (ARIMA-GARCH) model. In which, the ARIMA model is used as the mean equation of the GARCH model to model the travel time levels and the GARCH model is used to model the conditional variances of travel time. The proposed method is validated and evaluated using actual traffic flow data collected from the traffic monitoring system of Kunshan city. The evaluation results show that, compared with the conventional ARIMA model, the proposed model cannot significantly improve the forecasting performance of travel time levels but has advantage in travel time volatility forecasting. The proposed model can well capture the travel time heteroskedasticity and forecast the time-varying confidence intervals of travel time which can better reflect the volatility of observed travel times than the fixed confidence interval provided by the ARIMA model.
文摘History proves that some countries and regions benefited from international industry transfer, because of international industrial transfer can stimulate their economic growth.Thanks to the manufacturing transfer implemented by EU, USA, Japan and some Asian developed countries in 1980s, China’s economic situation has boomed over 30 years. Textile industry as a traditional industry in China has its own competitive advantage. It can be confirmed that textile industry will play an important role during the fourth Industry transfer period. So, who will be the winner this time?
文摘Panzhihua, in south Sichuan’s basin, is aptly called West China’s Industrial Pearl, and "treasure bowl." This city is well known as the home of Panzhihua Iron and Steel Group Company and Ertan Hydropower Station. At the beginning of 2004, two major events thrust this city into the limelight.
文摘FOR the first time In its 16-year existence, the Milken Institute Global Conference 2013 in Los Angeles included four panels devoted to discussing African opportunities and challenges. A decade ago, perceptions of Africa were extremely negative. The May 2000 cover of a major international publication described Africa as “The Hopeless Continent.” Fast forward to 2011, and the same magazine ran a more optimistic headline: "Africa Rising." There is a media frenzy focused on Africa and the continent's gains are tangible.
文摘While China's tea consumption slows,globally tea lovers are sipping with increasing zest WHEN you think of China one of the first things that comes to mind is tea.It is a staple beverage intrinsically woven into the tapestry of Chinese lifestyle in a country that has the earliest records of tea drinking.China today shares its
文摘THE first thing Cai Banghong does every morning is to look at the sales figure of various tea brands on his online store. Hmongling Tea Garden, before posting promotional information and collecting customers' feed- back to help target his products Cai spent two decades growing his tea company from a small backroom operation into a modern tea company integrating planting, processing and sales.
基金Supported by Key Scientific Research Program of Guangxi(AB16380133,AB16380140)Agricultural Science and Technology Achievement Transformation Fund of Guangxi(1346004-16)+1 种基金the Scientific and Technological Development Project of Guangxi Academy of Agricultural Sciences[2015YT24,201303(A)]Agricultural Science and Technology Achievement Transformation Fund of Ministry of Science and Technology(2013GB2E100378)~~
文摘To determine the optimal time for harvesting the seeds of Gui 39722, which is the female parent of a newly-developed maize hybrid Guidan 0810, the cobs of Gui 39722 were harvested 31 (the first stage), 34 (the second stage), 37 (the third stage), 40 (the fourth stage), 43 (the fifth stage) and 46 (the sixth stage) d after pollination and oven dried at 38 ~C to constant weight. Then, the 1 000-ker- nel weight, germination rate and the agronomic traits of three-leaf seedlings were measured and compared. The results showed that the seeds of Gui 39722 harvest- ed 43 d after pollination (the fifth stage) had the greatest germination rate, seedling height, vigor index, root dry weight, shoot dry weight and germination potential, and high 1 000-kernel weight (very close to the highest level), root length, number of roots per seedling and root-shoot ratio. Therefore, 43 d after pollination was the op- timal time for harvesting the seeds of Gui 39722, when the effective accumulated temperature after pollination reached 780.7 ℃ and the ear leaf dried. The seeds harvested at this stage had the highest yield and the best quality. Field sampling revealed that 89.00% to 95.00% (with an average of 91.15%) of the seedlings of six stages of seeds grew well.
文摘AIM:To identify the determinants of endoscopic submucosal dissection(ESD) operation time.METHODS:This investigation was conducted as a single-center,prospective study in which ESD was performed by the same endoscopist at the Chinese PLA General Hospital.A total of 173 patients underwent ESD operations performed by Dr.Lu from July 2007 to December 2011,and 183 lesions were enrolled.Patient gender,age,tumor location,gross type,tumor size,pathological type and adhesions were recorded prospectively.The order of treatment represented the experience of the operator.Univariate analysis and multivariate analysis were performed to evaluate the relationships between these factors and ESD procedure time.RESULTS:Univariate analysis showed the ESD time was closely related to the gender(P = 0.0210),tumor size(P < 0.0001),location(P < 0.0001),gross type(P < 0.0001) and adhesion(P = 0.0010).The surgical proficiency level was associated with ESD time in unit area(P < 0.0001).Multivariate analysis revealed that the ESD time was positively correlated with tumor size(P < 0.0001),adhesion(P < 0.0001) and location(P < 0.0001),but negatively correlated with surgical proficiency level(P = 0.0046).CONCLUSION:Large tumor size,adjacency to the cardia,and adhesion are predictors of a long ESD time,whereas high surgical proficiency level predicts a short ESD time.
文摘While emergency medical service (EMS) response time (ERT) is a major factor associated with the survival of patients with cardiovascular disease (CVD), relatively few studies have explored the factors associated with ERT. This study aimed to assess the current status of ERT and to identify the factors affecting ERT in patients with CVD in China. Between January 1, 2011 and December 31, 2015, EMS responses to CVD incidents in Guangzhou, China, were examined. The primary outcome was ERT, defined as the time from receipt of an emergency call to the arrival of paramedics on the scene. Factors associated with ERT were evaluated by multivariable logistic regression. A total of 44 383 CVD incidents were analysed. The median ERT was 12.58 min (interquartile range=9.98-15.67). Among the risk factors, distance (OR=13.73, 95% CI=11.76- 16.04), level of hospital (OR=1.57, 95% CI=1.40-1.75), and site of the incident (OR=1.53, 95% CI=1.38-1.69) were the top three significant factors affecting the ERT. Our results suggest that greater attention should be given to factors affecting the ERT. It is essential to make continuous efforts to promote the development of effective interventions to reduce the response time.
基金supported by the National Natural Science Foundation of China(61673198)the Provincial Natural Science Foundation of Liaoning Province(20180550473)
文摘This paper will investigate global exponential stability analysis for a class of switched positive nonlinear systems under minimum dwell time switching, whose nonlinear functions for each subsystem are constrained in a sector field by two odd symmetric piecewise linear functions and whose system matrices for each subsystem are Metzler. A class of multiple time-varying Lyapunov functions is constructed to obtain the computable sufficient conditions on the stability of such switched nonlinear systems within the framework of minimum dwell time switching.All present conditions can be solved by linear/nonlinear programming techniques. An example is provided to demonstrate the effectiveness of the proposed result.
基金Project(51178158) supported by the National Natural Science Foundation of ChinaProjects(2010HGZY0010, 2011HGBZ0936) supported by the Fundamental Research Funds for the Central Universities of China
文摘Referring to the 1 248 survey data of rural population in 14 provinces of China, the influencing factors of trip time choice were analyzed. Based on the basic theory of disaggregate model and its modelling method, nine grades were selected as the alternatives of trip time, the variables affecting time choice and the method getting their values were determined, and a multinomial logit (MNL) model was developed. Another 1 200 trip data of rural population were selected to testify the model's validity. The result shows that the maximum absolute error of each period between calculated value and statistic is 3.6%, so MNL model has high calculation accuracy.
基金supported by the People’s Liberation Army Fund for Special Projects of Medical Sciences, No. 06G114
文摘This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutively expressing enhanced green fluorescence protein, or media alone, were injected into the subarachnoid space of adult rats at 1 hour (acute stage), 7 days (subacute stage) and 28 days (chronic stage) after contusive spinal cord injury. Results showed that grafted neural progenitor cells migrated and aggregated around the blood vessels of the injured region, and infiltrated the spinal cord parenchyma along the tissue spaces in the acute stage transplantation group. However, this was not observed in subacute and chronic stage transplantation groups. 04- and glial fibrillary acidic protein-positive cells, representing oligodendrocytes and astrocytes respectively, were detected in the core of the grafted cluster attached to the cauda equina pia surface in the chronic stage transplantation group 8 weeks after transplantation. Both acute and subacute stage transplantation groups were negative for 04 and glial fibrillary acidic protein cells. Basso, Beattie and Bresnahan scale score comparisons indicated that rat hind limb locomotor activity showed better recovery after acute stage transplantation than after subacute and chronic transplantation. Our experimental findings suggest that the subarachnoid route could be useful for transplantation of neural progenitor cells at the acute stage of spinal cord injury. Although grafted cells survived only for a short time and did not differentiate into astrocytes or neurons, they were able to reach the parenchyma of the injured spinal cord and improve neurological function in rats. Transplantation efficacy was enhanced at the acute stage in comparison with subacute and chronic stages.
基金supported by the National Natural Science Foundation of China(61872204)the Natural Science Foundation of Heilongjiang Province of China(F2015025)。
文摘This paper proposes a multivariable fixed-time leaderfollower formation control method for a group of nonholonomic mobile robots, which has the ability to estimate multiple uncertainties. Firstly, based on the state space model of the leader-follower formation, a multivariable fixed-time formation kinematics controller is designed. Secondly, to overcome uncertainties existing in the nonholonomic mobile robot system, such as load change,friction, external disturbance, a multivariable fixed-time torque controller based on the fixed-time disturbance observer at the dynamic level is designed. The designed torque controller is cascaded with the formation controller and finally realizes accurate estimation of the uncertain part of the system, the follower tracking of reference velocity and the desired formation of the leader and the follower in a fixed-time. The fixed-time upper bound is completely determined by the controller parameters, which is independent of the initial state of the system. The multivariable fixed-time control theory and the Lyapunov method are adopted to ensure the system stability.Finally, the effectiveness of the proposed algorithm is verified by the experimental simulation.