Neurodegenerative disease is a condition in which subpopulations of neuronal cells of the brain and spinal cord are selectively lost. A common event in many neurodegenerative diseases, such as Parkinson＇s disease （P...Neurodegenerative disease is a condition in which subpopulations of neuronal cells of the brain and spinal cord are selectively lost. A common event in many neurodegenerative diseases, such as Parkinson＇s disease （PD）, Alzheimer＇s disease （AD）, amyotrophic lateral sclerosis （ALS）, multiple sclerosis and prion diseases, is the increased level of endoplasmic reticulum （ER） stress caused by accumulation and deposits of inclusion bodies that contain abnormal aggregated proteins. However, the exact contributions to and causal effects of ER stress in neuron degeneration are not clear （Lindholm et al., 2006）.展开更多
This study aimed to research existing death education literature,explore its necessity,forms,and impacts,and provide references for regions lacking it,by conducting a scoping review of 18 documents from 10 databases,f...This study aimed to research existing death education literature,explore its necessity,forms,and impacts,and provide references for regions lacking it,by conducting a scoping review of 18 documents from 10 databases,finding high demand among nursing students and positive effects of various teaching strategies,concluding that death education is necessary and future research should focus on enhancing evaluation timeliness and standardizing criteria to develop a complete system.展开更多
Objective:This study aimed to explore the understanding of healthcare providers working in the internal medicine department in Shanghai regarding a good death.Methods:The data of the study was collected using face-to-...Objective:This study aimed to explore the understanding of healthcare providers working in the internal medicine department in Shanghai regarding a good death.Methods:The data of the study was collected using face-to-face semi-structured interviews.Through purposive sampling,16 physicians and 13 nurses who had experiences of caring for adult patients with life-threatening illnesses at the end-of-life stage in Shanghai were interviewed.The interviews were analyzed using qualitative content analysis.Results:Six characteristics of a good death emerged:no suffering,companionship and care,no worries or concerns,dying with dignity,involvement and acceptance,and less impact on the family.Eighteen categories were identified:dying without experiencing suffering;being relieved of symptoms and suffering;being relieved of psychological suffering;avoiding the use of futile treatment and resuscita-tion;being cared for and accompanied by family;receiving good health care;having a meaningful life without regrets;making good arrangements for family issues;having a chance to say goodbye;having a quality life before death;dying in a decent environment;the personal will to be respected;maintaining the integrity of the body;death of the patient being accepted by the family and healthcare providers;the death occurred despite the best efforts to care for the patient;limited financial and care burden;shortly affected quality of life of the patient;and improved family cohesion.Conclusion:Family members’early involvement in caring for patients at the end-of-life stage helps achieve a good death.For patients with a terminal illness,avoiding unnecessary medical treatment and resuscitation could be the first step in achieving better patient death and promoting the development of advanced care planning in the mainland of China.展开更多
Objective This study aimed to explore the perceptions of good death of the older adults living in Bang Nang Li Sub-District,Amphawa District,Samut Songkhram Province,Thailand.Method The data of the study was collected...Objective This study aimed to explore the perceptions of good death of the older adults living in Bang Nang Li Sub-District,Amphawa District,Samut Songkhram Province,Thailand.Method The data of the study was collected using in-depth interviews between October 2019 to January 2020.The data collected a total of 14 older adults who had firsthand experience in caring for terminally ill patients were recruited for the study.Content analysis was employed to analyze qualitative data.Results The results of this study revealed the perceptions of good death which were categorized into three main themes and eight sub-themes,including 1)death without suffering(not suffering from life support devices,dying with care);2)natural death(death with the end of life expectancy,death with illness or ailments);and 3)death without the worries(preparation for death,spiritual and belief practice toward preparation for death,family and property management before death,death among family members and at their familiar place).Conclusion The findings of this research provided the insight to clarify the understanding of the perceptions on a good death of older adults.The findings can be used to support the practice and management of nursing education and health care providers who have to be involved in palliative care for terminally ill older adults.展开更多
基金supported by the Paul and Harriett Campbell Fund for ALS Researchthe Zimmerman Family Love Fundthe Judith&Jean Pape Adams Charitable Foundation
文摘Neurodegenerative disease is a condition in which subpopulations of neuronal cells of the brain and spinal cord are selectively lost. A common event in many neurodegenerative diseases, such as Parkinson＇s disease （PD）, Alzheimer＇s disease （AD）, amyotrophic lateral sclerosis （ALS）, multiple sclerosis and prion diseases, is the increased level of endoplasmic reticulum （ER） stress caused by accumulation and deposits of inclusion bodies that contain abnormal aggregated proteins. However, the exact contributions to and causal effects of ER stress in neuron degeneration are not clear （Lindholm et al., 2006）.
文摘This study aimed to research existing death education literature,explore its necessity,forms,and impacts,and provide references for regions lacking it,by conducting a scoping review of 18 documents from 10 databases,finding high demand among nursing students and positive effects of various teaching strategies,concluding that death education is necessary and future research should focus on enhancing evaluation timeliness and standardizing criteria to develop a complete system.
文摘Objective:This study aimed to explore the understanding of healthcare providers working in the internal medicine department in Shanghai regarding a good death.Methods:The data of the study was collected using face-to-face semi-structured interviews.Through purposive sampling,16 physicians and 13 nurses who had experiences of caring for adult patients with life-threatening illnesses at the end-of-life stage in Shanghai were interviewed.The interviews were analyzed using qualitative content analysis.Results:Six characteristics of a good death emerged:no suffering,companionship and care,no worries or concerns,dying with dignity,involvement and acceptance,and less impact on the family.Eighteen categories were identified:dying without experiencing suffering;being relieved of symptoms and suffering;being relieved of psychological suffering;avoiding the use of futile treatment and resuscita-tion;being cared for and accompanied by family;receiving good health care;having a meaningful life without regrets;making good arrangements for family issues;having a chance to say goodbye;having a quality life before death;dying in a decent environment;the personal will to be respected;maintaining the integrity of the body;death of the patient being accepted by the family and healthcare providers;the death occurred despite the best efforts to care for the patient;limited financial and care burden;shortly affected quality of life of the patient;and improved family cohesion.Conclusion:Family members’early involvement in caring for patients at the end-of-life stage helps achieve a good death.For patients with a terminal illness,avoiding unnecessary medical treatment and resuscitation could be the first step in achieving better patient death and promoting the development of advanced care planning in the mainland of China.
基金The research grant for a potential lecturer was supported by Suan Sunadha Rajabhat Thailand.
文摘Objective This study aimed to explore the perceptions of good death of the older adults living in Bang Nang Li Sub-District,Amphawa District,Samut Songkhram Province,Thailand.Method The data of the study was collected using in-depth interviews between October 2019 to January 2020.The data collected a total of 14 older adults who had firsthand experience in caring for terminally ill patients were recruited for the study.Content analysis was employed to analyze qualitative data.Results The results of this study revealed the perceptions of good death which were categorized into three main themes and eight sub-themes,including 1)death without suffering(not suffering from life support devices,dying with care);2)natural death(death with the end of life expectancy,death with illness or ailments);and 3)death without the worries(preparation for death,spiritual and belief practice toward preparation for death,family and property management before death,death among family members and at their familiar place).Conclusion The findings of this research provided the insight to clarify the understanding of the perceptions on a good death of older adults.The findings can be used to support the practice and management of nursing education and health care providers who have to be involved in palliative care for terminally ill older adults.
