Secretion systems, macromolecules to pass which can mediate the across cellular membranes, are essential for virulent and genetic material exchange among bacterial species[1]. Type IV secretion system （T4SS） is one ...Secretion systems, macromolecules to pass which can mediate the across cellular membranes, are essential for virulent and genetic material exchange among bacterial species[1]. Type IV secretion system （T4SS） is one of the secretion systems and it usually consists of 12 genes： VirB1, VirB2 ...VirB11, and VirD4[2]. The structure and molecular mechanisms of these genes have been well analyzed in Gram-negative strains[3] and Gram-positive strains were once believed to be lack of T4SS. However, some recent studies revealed that one or more virB/D genes also exist in some kinds of Gram-positive bacteria and play similar role, and form a T4SS-like system[3]. The VirBl-like, VirB4, VirB6, and VirD4 genes were identified in the chromosome of Gram-positive bacterium Streptococcus suis in our previous studies and their role as important mobile elements for horizontal transfer to recipients in an 89 K pathogenicity island （PAl） was demonstrated[45]. However, their structure and molecular mechanisms in other strains, especially in Gram-positive strains, are remained unclear.展开更多
目的分析基于看图对话工具的健康教育在2型糖尿病(Diabetes Mellitus Type 2,T_(2)DM)患者中的应用效果。方法随机选取2021年1月—2022年12月厦门大学附属第一医院收治的120例T_(2)DM患者为研究对象,使用随机数表法将其分为两组,每组60...目的分析基于看图对话工具的健康教育在2型糖尿病(Diabetes Mellitus Type 2,T_(2)DM)患者中的应用效果。方法随机选取2021年1月—2022年12月厦门大学附属第一医院收治的120例T_(2)DM患者为研究对象,使用随机数表法将其分为两组,每组60例。对照组患者接受常规健康教育,研究组患者采用基于看图对话工具的健康教育模式。对比两组患者的T_(2)DM健康知识认知情况评分、T_(2)DM自我管理行为量表(Diabete Self Care Scale,DSCS)评分、健康调查简表(MOS Item Short from Health Survey,SF-36)评分,以及护理满意度。结果研究组患者对于T_(2)DM健康知识的总认知率(96.67%)高于对照组(83.33%),差异有统计学意义(χ^(2)=5.926,P<0.05)。干预前,两组DSCS量表、SF-36量表评分对比,差异无统计学意义(P均>0.05);干预8周后,研究组DSCS量表评分(89.65±10.50)分、SF-36量表评分(88.36±6.85)分,均高于对照组的(82.67±8.45)分、(80.64±5.77)分,差异有统计学意义(t=4.012、6.677,P均<0.05)。研究组护理总满意率较对照组高,差异有统计学意义(P<0.05)。结论基于看图对话工具的健康教育能够有效提升T_(2)DM患者对于疾病知识的认知程度,改善自我管理行为,保障生活质量,且提高了护理满意度。展开更多
基金supported by the National Natural Science Foundation of China (No. 81201322)the Priority Project on Infectious Disease Control and Prevention 2011ZX10004-001 and 2013ZX10003006-002 by the Chinese Ministry of Science and Technology and the Chinese Ministry of Healththe Foundation of State Key Laboratory for Infectious Disease Prevention and Control (Grand No. 2011SKLID303)
文摘Secretion systems, macromolecules to pass which can mediate the across cellular membranes, are essential for virulent and genetic material exchange among bacterial species[1]. Type IV secretion system （T4SS） is one of the secretion systems and it usually consists of 12 genes： VirB1, VirB2 ...VirB11, and VirD4[2]. The structure and molecular mechanisms of these genes have been well analyzed in Gram-negative strains[3] and Gram-positive strains were once believed to be lack of T4SS. However, some recent studies revealed that one or more virB/D genes also exist in some kinds of Gram-positive bacteria and play similar role, and form a T4SS-like system[3]. The VirBl-like, VirB4, VirB6, and VirD4 genes were identified in the chromosome of Gram-positive bacterium Streptococcus suis in our previous studies and their role as important mobile elements for horizontal transfer to recipients in an 89 K pathogenicity island （PAl） was demonstrated[45]. However, their structure and molecular mechanisms in other strains, especially in Gram-positive strains, are remained unclear.
文摘目的分析基于看图对话工具的健康教育在2型糖尿病(Diabetes Mellitus Type 2,T_(2)DM)患者中的应用效果。方法随机选取2021年1月—2022年12月厦门大学附属第一医院收治的120例T_(2)DM患者为研究对象,使用随机数表法将其分为两组,每组60例。对照组患者接受常规健康教育,研究组患者采用基于看图对话工具的健康教育模式。对比两组患者的T_(2)DM健康知识认知情况评分、T_(2)DM自我管理行为量表(Diabete Self Care Scale,DSCS)评分、健康调查简表(MOS Item Short from Health Survey,SF-36)评分,以及护理满意度。结果研究组患者对于T_(2)DM健康知识的总认知率(96.67%)高于对照组(83.33%),差异有统计学意义(χ^(2)=5.926,P<0.05)。干预前,两组DSCS量表、SF-36量表评分对比,差异无统计学意义(P均>0.05);干预8周后,研究组DSCS量表评分(89.65±10.50)分、SF-36量表评分(88.36±6.85)分,均高于对照组的(82.67±8.45)分、(80.64±5.77)分,差异有统计学意义(t=4.012、6.677,P均<0.05)。研究组护理总满意率较对照组高,差异有统计学意义(P<0.05)。结论基于看图对话工具的健康教育能够有效提升T_(2)DM患者对于疾病知识的认知程度,改善自我管理行为,保障生活质量,且提高了护理满意度。
