Dislocation of primary total hip arthroplasty:Analysis of risk factors and preventive options

Total hip arthroplasty(THA)is one of the most successful elective operations in orthopedic surgery for improving pain and functional disability in patients with end-stage joint disease.However,dislocation continues to be a troublesome complication after THA,as it is a leading cause of revision and is associated with substantial social,health,and economic costs.It is a relatively rare,usually early occurrence that depends on both the patients’characteristics and the surgical aspects.The most recent and important finding is the special attention to be given preoperatively to spinopelvic mobility,which is closely related to the incidence of dislocation.Consequently,clinical and radiographic assessment of the lumbar spine is mandatory to identify an altered pelvic tilt that could suggest a different positioning of the cup.Lumbar spinal fusion is currently considered a risk factor for dislocation and revision regardless of whether it is performed prior to or after THA.Surgical options for its treatment and prevention include the use of prostheses with large diameter of femoral head size,dual mobility constructs,constrained liners,and modular neck stems.

Research on the Impact of China’s Foreign Trade Technology Spillover on Green Total Factor Productivity of Countries Along the“Belt and Road”:Based on the Institutional Quality Threshold Effect

China’s growing trade with countries along the“Belt and Road”Initiative is accompanied by a focus on green development.Based on the panel data from 2007 to 2018,this paper establishes a threshold regression model to empirically analyze the institutional quality threshold effect of China’s foreign trade technology spillover on the GTFP of countries along the“Belt and Road.”The results show that China’s foreign trade technology spillover has a significant institutional quality double threshold effect on the green total factor productivity of the countries along the“Belt and Road.”As the institutional quality of the countries along the“Belt and Road”crosses a specific threshold value,the impact of China’s foreign trade technology spillover on the green total factor productivity of the countries along the“Belt and Road”has a significant positive promoting effect,and corresponding suggestions are put forward.

The impact of market coordination on urban green total factor productivity:An analysis of the mediating effect of factor misallocation

Promoting market coordination and enhancing the efficiency of green growth is a necessity for China’s effective economic development.Using panel data from 2007 to 2020,this paper conducts a comprehensive study on 226 cities at the prefecture-level and above,combining theoretical analysis and empirical tests to systematically explore the impact of market cohesion on urban green total factor productivity(GTPF)and the mediating role of factor mismatch.Findings demonstrate that market coordination maximizes urban GTPF.At the mechanism level,factor mismatch plays a mediating role,and market coordination can enhance GTPF by addressing capital and labor mismatch.In terms of heterogeneity analysis,market coordination significantly promotes GTPF positively in the east-central region and negatively in the western region.In terms of technological progress and technical efficiency,the eastern region shows a larger significance than the central and western regions combined.In view of the above,the concept of market coordination development has been implemented to promote GTFP in cities.

Does innovative city pilot policy promote urban green growth in China?An analysis of green total factor productivity,2005-2020

The innovative city pilot policy(ICPP)is an essential manifestation of China’s construction of an innovative and green-driven development country.We incorporated urban green total factor productivity(GTFP)growth into the evaluation of ICPP.Based on the panel data of 223 cities in China from 2005 to 2020,we used the difference-in-differences model to empirically assess the influence and mechanism of the ICPP on urban GTFP growth.The main results show that(i)The ICPP has maintained an effectively fluctuating promotion on urban GTFP growth,mainly manifested in the urban green technological progress improvement.(ii)The ICPP has urban heterogeneity in promoting GTFP growth in pilot cities,mainly affecting key cities such as provincial capitals.(iii)The interaction between the agglomeration of producer services and the ICPP inhibits GTFP growth in pilot cities.

The Impact of the Establishment of National High-tech Zones on Total Factor Productivity of Chinese Enterprises

The National High-tech Zone(NHTZs)is an important strategic platform for cultivating high-tech industries and realizing high-quality economic development in China.Based on the combined data from 2006 to 2014 of the industrial enterprise database,the customs database,and the China Development Zones Audit and Announcement Catalogue(abbreviated asthe Catalogue),this paper systematically investigates the influence of the construction of NHTZs on enterprise’s total factor productivity(TFP).Results show that NHTZs have a positive impact on the TFP of enterprises in the zone,and this conclusion is still valid after considering endogeneity problems.Furthermore,the above productivity effects of NHTZs are heterogeneous in terms of enterprise ownership,external environment and establishment time,and NHTZs have greater stimulation effects on enterprise productivity after comparing with other types of functional zones.An investigation of the specific mechanisms at play shows that NHTZs promote the TFP of enterprises in the zone through the release of preferential policies,strengthening the“technology spillover effects”of imported intermediate goods,enhancing enterprise’s innovation ability and attracting talent.In addition,based on the decomposition of industry productivity,this paper also investigates the impact of NHTZs on changes in industry productivity and finds that NHTZs promote the overall productivity of specific industries mainly by stimulating the productivity improvement of incumbent enterprises and expanding the market share of high-productivity enterprises.Moreover,the preferential policies of NHTZs do not significantly stimulate high-productivity enterprises to enter the zones,nor do they cause low-productivity enterprises to exit.This research is helpful in objectively evaluating the economic effects of the NHTZs in China and in providing a theoretical basis for its further adjustment.

Empirical Analysis of the Impact of Green Finance and Technological Progress on Total Factor Productivity in China’s Industrial Sector

The enhancement of industrial green total factor productivity is pivotal for achieving high-quality and sustainable economic development.This study assesses China’s performance using the SBM-GML model,employing province-level panel data spanning from 2004 to 2020.Furthermore,we examine the influence of green finance and technological progress on industrial green total factor productivity using a spatial econometric model.The findings uncover that the relationship between the level of green financial development and industrial green total factor productivity follows a U-shaped curve.Initially,low levels of green financial development exert a suppressive effect on industrial green total factor productivity,proving ineffective in the short term.However,with the progression of green finance development,a positive and significant long-term impact on industrial green total factor productivity emerges.Moreover,technological progress demonstrates a noteworthy promotional effect on industrial green total factor productivity.The analysis delves deeper into revealing that industrial structure and environmental regulation intensity exhibit a significant negative relationship with industrial green total factor productivity.In contrast,both energy structure and education level showcase a substantial positive relationship with industrial green total factor productivity.

Technical Components of Total Factor Productivity Growth in Malaysian Manufacturing Industry

This article attempts to disaggregate and explore the components of TFP growth that contribute to changes in output, scale of production, and allocative efficiency and technical efficiency of the Malaysian manufacturing sector. The total factor productivity (TFP) concept defined as total output per unit of all inputs used in the production of an industry has gained a prominent place in academia. The investigation on TFP growth is obviously useful for identifying sources of output growth in the development of an industry. The TFP growth is often interchangeably understood as the technical progress or changes in technology as the sole contributor to economic development. Nonetheless there are other factors contributing to its substance. Knowledge on these technical changes would help decision makers to realize the strengths and weaknesses that contribute to the growth and development of an industry. Alternatively this research would be more beneficial in the case of cross-industry or cross-country comparative studies in order to plan for developmental goal. In such a case a model industry or country can be chosen that exhibits special growth features.

Socio-demographic factors impact time to discharge following total knee arthroplasty

AIM To determine social, logistical and demographic factors that influence time to discharge in a short stay pathway(SSP) by following total knee arthroplasty(TKA). METHODS The study included primary TKA's performed in a highvolume arthroplasty center from January 2016 through December 2016. Potential variables associated with increased hospital length of stay(LOS) were obtained from patient medical records. These included age, gender, race, zip code, body mass index(BMI), number of pre-operative medications used, number of narcotic medications used, number of patient reported allergies(PRA), simultaneous bilateral surgery, tobacco use, marital status, living arrangements, distance traveled for surgery, employment history, surgical day of the week, procedure end time and whether the surgery was performed during a major holiday week. Multivariate step-wise regression determined the impact of social, logistical and demographic factors on LOS. RESULTS Eight hundred and six consecutive primary SSP TKA's were included in this study. Patients were discharged at a median of 49 h(post-operative day two). The following factors increased LOS: Simultaneous bilateral TKA [46.1 h longer(P < 0.001)], female gender [4.3 h longer(P = 0.012)], age [3.5 h longer per ten-year increase in age(P < 0.001)], patient-reported allergies [1.1 h longer per allergy reported(P = 0.005)], later procedure endtimes [0.8 h longer per hour increase in end-time(P = 0.004)] and Black or African American patients [6.1 h longer(P = 0.047)]. Decreased LOS was found in married patients [4.8 h shorter(P = 0.011)] and TKA's performed during holiday weeks [9.4 h shorter(P = 0.011)]. Non-significant factors included: BMI, median income, patient's living arrangement, smoking status, number of medications taken, use of pre-operative pain medications, distance traveled to hospital, and the day of surgery. CONCLUSION The cost of TKA is dependent upon LOS, which is affected by multiple factors. The clinical care team should acknowledge socio-demographic factors to optimize LOS.

Total Variation Constrained Non-Negative Matrix Factorization for Medical Image Registration

This paper presents a novel medical image registration algorithm named total variation constrained graphregularization for non-negative matrix factorization(TV-GNMF).The method utilizes non-negative matrix factorization by total variation constraint and graph regularization.The main contributions of our work are the following.First,total variation is incorporated into NMF to control the diffusion speed.The purpose is to denoise in smooth regions and preserve features or details of the data in edge regions by using a diffusion coefficient based on gradient information.Second,we add graph regularization into NMF to reveal intrinsic geometry and structure information of features to enhance the discrimination power.Third,the multiplicative update rules and proof of convergence of the TV-GNMF algorithm are given.Experiments conducted on datasets show that the proposed TV-GNMF method outperforms other state-of-the-art algorithms.

Changes in Total Factor Productivity,Technological Progress and Efficiency of Banana Industry in China

Based on the DEA-based Malmquist index method,the total factor productivity was calculated for 5 major banana production areas in 2003-2004,and it was further divided into technological progress and technical efficiency.The results show that the total factor productivity of banana industry in China was 1.3% in the sample period,mainly due to technological progress,the average growth rate was 2.6%,while the pure technical efficiency and scale efficiency was -0.1% and -1.2% respectively.The improvement of total factor productivity in banana industry in China relied mainly on technological progress,cultivation of new banana varieties,management of high quality cultivation,popularization and application of water conservation and fertilizer saving technology,and injury-free picking technologies.The pure technical efficiency and scale efficiency of banana production were negative,indicating that the management level of banana was not high.The effect of scale economy of this industry through agglomeration and consolidation is still to be practiced.Banana growers should promote the improvement of large scale and management level of the banana industry at the same time of promoting the technological progress.

Dynamic analysis of spatial convergence of green total factor productivity in China's primary provinces along its Belt and Road Initiative

This paper focuses on China's primary provinces along its Belt and Road Initiative,measures and analyses the provincial green total factor productivity (GTFP) development by GML index based on SBM directional distance function,discusses the temporal evolution characteristics of spatial convergence of the provincial GTFP under multiple spatial weight matrices,and estimates the net effect of China's Belt and Road Initiative on the development gap of provincial GTFP by regression discontinuity.The research shows that the provincial GTFP is generally good while the internal gap is relatively large.There is spatial absolute βconvergence and condition βconvergence in provincial GTFP,and the convergence speed has been signifcantly accelerated since the construction of China's Belt and Road Initiative.The current low economy level and infrastructure allocation efficiency of primary provinces restrict the GTFP development,while government expenditure has promoted the GTFP development,trade between provinces and countries along China's Belt and Road Initiative is negative to GTFP.China's Belt and Road Initiative has significantly narrowed the gap of provincial GTFP development with the net effect of-0.016.

Risk factors for operative morbidity and mortality in gastric cancer patients undergoing total gastrectomy

AIM: To study the risk factors for morbidity and mortality following total gastrectomy. METHODS: We retrospectively reviewed the record of 125 consecutive patients who underwent tota gastrectomy for gastric cancer at the Second Affi liated Hospital of Zhejiang University School of Medicine between January 2003 and March 2008. RESULTS: The overall morbidity rate was 20.8% (27 patients) and the mortality rate was 3.2% (4 patients) Morbidity rates were higher in patients aged over 60 [odds ratio (OR) 4.23 (95% confidence interval (CI 1.09 to 12.05)], with preoperative comorbidity [with vs without, OR 1.25 (95% CI 1.13 to 8.12)], when the combined resection was performed [combined resection vs total gastrectomy only, OR 2.67 (95% C 1.58 to 5.06)]. CONCLUSION: Age, preoperative comorbidity and combined resection were independently associated with the rate of morbidity after total gastrectomy fo gastric cancer.

Successful Management of Wound Dehiscence after Total Knee Arthroplasty by Topically Using Recombinant Basic Fibroblast Growth Factor

Wound complications are estimated to be affected in about 9% of TKA patients, which may increase the risk of deep periprosthetic infection and results in re-operation, joint fusion, or amputation. Here we have reported a female patient who suffered wound rupture due to early post-operation mobilization and weight-bearing. The wound dehiscence was successfully managed by applying recombinant basic fibroblast growth factor-2 and anti-infective treatment without removing prosthetic joint.

Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway

AIM To explore the protective effects and underlying mechanisms of total polysaccharides of the Sijunzi decoction(TPSJ) on the epithelial barriers in vitro. METHODS Caco-2 cell monolayers were treated with or without TPSJ in the presence or absence of TNF-α, and paracellular permeability and transepithelial electrical resistance(TEER) were measured to evaluate the epithelial barrier function. Immunofluorescence and western blotting were respecti-vely used to evaluate the distribution and expression of the tight junction proteins claudin 1, claudin 2, zo3, and occludin in Caco-2 cells. western blotting was also used to evaluate the cellular expression of myosin light chain(MLC), phosphorylated MLC(pM LC), MLC kinase(MLCK), and nuclear factor(NF)-κB p65. RESULTS TPSJ promoted the proliferation of Caco-2 cells and inhibited TNF-α-induced secretion of pro-inflammatory cyto-kines. Furthermore, TPSJ significantly ameliorated both the reduction of TEER and the increased paracellular permeability observed in tumor necrosis factor(TNF)-α-damaged Caco-2 monolayers. Furthermore, TPSJ remarkably attenuated TNF-α-induced morphological changes, downregulated the expression of claudin 1, claudin 2, zo3, and occludin, and markedly suppressed TNF-α-mediated upregulation of p-MLC and MLCK expression. Finally, TPSJ inhibited the activation and expression of NF-κB p65. CONCLUSION Our results demonstrate that TPSJ alleviates the TNF-α-induced impairment of the intestinal epithelial cell barrier function by suppressing NF-κB p65-mediated phosphorylation of MLCK and MLC.

Annual Time-series Analyses of Total Gaseous Mercury Measurement and its Impact Factors on the Gongga Mountains in the Southeastern Fringe of the Qinghai-Tibetan Plateau

Long-term monitoring programs for measurement of atmospheric mercury concentrations are presently recognized as powerful tools for local,regional and global studies of atmospheric long-range transport processes,and they could also provide valuable information about the impact of emission controls on the global budget of atmospheric mercury,their observance and an insight into the global mercury cycle. China is believed to be an increasing atmospheric mercury emission source. However,only a few measurements of mercury,to our knowledge,have been done in ambient air over China. The highly-time resolved atmospheric mercury concen-trations have been measured at Moxi Base Station (102°72′E 29°92′N,1640 m asl) of the Gongga Alpine Ecosystem Observation and Experiment Station of Chinese Academy of Sciences (CAS) from May 2005 to June 2006 by using a set of Automatic Atmospheric Mercury Speciation Analyzers (Tekran 2537A). Measurements were carried out with a time resolution of every 15 minutes. The overall average total gaseous mercury (TGM) covering the measurement periods was 4±1.38 ng·m-3 (N=57310),which is higher than the global background level of approximately 1.5～2.0 ng·m-3. The measurements in all seasons showed a similar diurnal change pattern with a high concentration during daytime relative to nighttime and maximum concentration near solar noon and minimum concentration immediately before sunrise. The presence of diurnal TGM peaks during spring and summer was found earlier than that during autumn and winter. When divided seasonally,it was found that the concentrations of TGM were highest in winter with 6.13 ± 1.78 ng·m-3 and lowest in summer with 3.17 ± 0.67 ng·m-3. There were no significant differences in TGM among wind sectors during each season. Whereas Hg generally exhibited significant correlations with the parameters,such as temperature,saturated vapor pressure,precipitation,ultraviolet radiation (UV) and atmospheric pressure at the whole measurement stage,and the correlations varied seasonally. Our results suggest that the local or regional abundant geothermal activities,such as thermal spring,anthropogenic source processes and changes in meteorological conditions,regulate and affect Hg behavior in the study area.

Influencing Factors of Determination of Total Arsenic in Soil by Atomic Fluorescence(AFS-9760) Method

In this paper,the atomic fluorescence(AFS-9760)method used for the determination of total arsenic in soil was verified based on three national quality control samples GSS-8,GSS-25,and GSF-3.Under the conditions of negative pressure of 270 V,carrier gas flow of 300 m L/min,and shield flow of 1000 m L/min,the detection limit of the method was 0.0092 mg/kg;the precision of GSS-8,GSS-25,and GSF-3 was 3.96%,1.47%and 1.08%,and the accuracy was 3.07%,2.13%,2.93%respectively.In addition,the matters needing attention during this experiment,such as reagent factor,instrument conditions,calibration curve,etc.,were summarized.It provides certain reference for the determination of total arsenic content in soil by atomic fluorescence spectrometry.

Analysis of the Contribution of Total Factor Productivity to Agricultural Yield in Anhui Province

By analyzing data concerning agricultural development from 1981 to 2010 in Anhui Province,the total factor productivity and growth rate of agriculture from 1981 to 2010 are estimated empirically.By dividing years from 1981 to 2010 into several subintervals,this paper evaluates and analyzes initial stage of reform and opening up,soft landing stage,the stage of financial crisis,the stage of subprime mortgage crisis and the impact of all factors on total factor growth rate of agriculture.Then it analyzes the contribution of growth of total factor productivity to total yield of agricultural economy.The research finds that the growth of total factor productivity in Anhui Province is significant to agricultural development.

Assessing Total Factor Productivity for Soybean Production in China Based on DEA-Malmquist Index: 2005-2017

The low and slowly increasing soybean yield restricts the development of soybean production. Accurate measures of total factor productivity (TFP) for soybean production can be helpful in identifying conditions, institutions or policies that promote soybean production development in China. In this paper, TFP growth for soybean production was estimated for a panel data of 10 major soybean producing provinces from 2005 to 2017. Results reveal that TFP grew at an average rate of 1.3% over the whole period, with technical progress contributing 2.3% and efficiency change providing the other -1.0%. The change of TFP for soybean production over that time, whether increase or decline, was mainly derived by technical change except in three years (2005-2007). Positive TFP growth in the provinces of Liaoning and Inner Mongolia, and negative TFP growth in Hebei and Anhui were mainly driven by efficiency change, specifically scale efficiency change except pure technical efficiency in Liaoning.

Growth in Total Factor Productivity of Shandong Province for Environmental Constraints

This paper analyzed the total factor productivity of Shandong Province and its impact on the local economic environment through Malmquist-Luenberger productivity index. The results of the paper were included as follows. Without consideration of the environmental constraints, Index M of the total factor productivity of Shandong Province from high to low was Heze, Jinan, Qingdao, Weihai, Dongying, Zaozhuang, Jining, Tai'an, Dezhou, Liaocheng, Yantai, Zibo, Weifang, Linyi, Binzhou, Rizhao, Laiwu, among which Index M of Linyi, Binzhou, Rizhao, Laiwuwere were less than 1; taking the environmental constraints into account, Index ML of the total factor productivity of Shandong Province was reduced, from high to low was Jinan, Qingdao, Weihai, Yantai, Heze, Liaocheng, Tai'an, Weifang, Jining, Linyi, Zibo, Dongying, Zaozhuang, Rizhao, Laiwu, Binzhou, Dezhou, among which Index ML of 9 cities behind Jining were less than 1. In terms of the development mode, Jinan, Qingdao, Tai'an, Weihai, Jining and Heze were resource-conserving and environment-friendly cities; Dongying and Zaozhuang were resourceconserving and environment-polluted cities; Liaocheng, Linyi, Weifang and Yantai were resource-wasted and environment-friendly cities; Binzhou, Dezhou, Laiwu, Rizhao and Zibo were resource-wasted and environment-pol uted cities.

Total flavone of Abelmoschus manihot suppresses epithelial-mesenchymal transition via interfering transforming growth factor-β1 signaling in Crohn's disease intestinal fibrosis

AIM To explore the role and mechanism of total flavone of Abelmoschus manihot(TFA) on epithelial-mesenchymal transition(EMT) progress of Crohn's disease(CD) intestinal fibrosis.METHODS First,CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial(IEC-6) cells and select the optimal concentrations of TFA for our further studies.Then cell morphology,wound healing and transwell assays were performed to examine the effect of TFA on morphology,migration and invasion of IEC-6 cells treated with TGF-β1.In addition,immunofluorescence,real-time PCR analysis(q RT-PCR) and western blotting assays were carried out to detect the impact of TFA on EMT progress.Moreover,western blotting assay was performed to evaluate the function of TFA on the Smad and MAPK signaling pathways.Further,the role of co-treatment of TFA and si-Smad or MAPK inhibitors has been examined by q RTPCR,western blotting,morphology,wound healing andtranswell assays.RESULTS In this study,TFA promoted transforming growth factor-β1(TGF-β1)-induced(IEC-6) morphological change,migration and invasion,and increased the expression of epithelial markers and reduced the levels of mesenchymal markers,along with the inactivation of Smad and MAPK signaling pathways.Moreover,we revealed that si-Smad and MAPK inhibitors effectively attenuated TGF-β1-induced EMT in IEC-6 cells.Importantly,co-treatment of TFA and si-Smad or MAPK inhibitors had better inhibitory effects on TGF-β1-induced EMT in IEC-6 cells than either one of them.CONCLUSION These findings could provide new insight into the molecular mechanisms of TFA on TGF-β1-induced EMT in IEC-6 cells and TFA is expected to advance as a new therapy to treat CD intestinal fibrosis.