Saponins extracted from Panax notoginseng are neuroprotective, but the mechanisms underlying this effect remain unclear. In the present study, we established a rat model of thoracic（T10） spinal cord transection, and...Saponins extracted from Panax notoginseng are neuroprotective, but the mechanisms underlying this effect remain unclear. In the present study, we established a rat model of thoracic（T10） spinal cord transection, and injected Panax notoginseng saponins（100 mg/kg） or saline 30 minutes after injury. Locomotor functions were assessed using the Basso, Beattie, and Bresnahan（BBB） scale from 1 to 30 days after injury, and immunohistochemistry was carried out in the ventral horn of the spinal cord at 1 and 7 days to determine expression of nerve growth factor（NGF） and brain-derived neurotrophic factor（BDNF）. Our results show that at 7–30 days post injury, the BBB score was higher in rats treated with Panax notoginseng saponins than in those that received saline. Furthermore, at 7 days, more NGF- and BDNF-immunoreactive neurons were observed in the ventral horn of the spinal cord of rats that had received Panax notoginseng saponins than in those that received saline. These results indicate that Panax notoginseng saponins caused an upregulation of NGF and BDNF in rats with spinal cord transection, and improved hindlimb motor function.展开更多
Chinese agriculture is undergoing a transformation process from traditional agriculture into modern agricultrue.This article discusses how land. labor, fertilizer, machinery etc. are used in agricultural production of...Chinese agriculture is undergoing a transformation process from traditional agriculture into modern agricultrue.This article discusses how land. labor, fertilizer, machinery etc. are used in agricultural production of different regions. reveals the influence of natural conditions and economic level on the utilization of modern agricultural factors. It proposes a system of allocation hoes of regional agricultural productive factors and points out the development stage and tendency of allocation of agricultural productive factors in different regions.展开更多
The outstanding performance of Shanghai students in the 4th Programme for International Student Assessment(PISA 2009)gained widespread attention at home and abroad.In this paper,the authors attribute this outstanding ...The outstanding performance of Shanghai students in the 4th Programme for International Student Assessment(PISA 2009)gained widespread attention at home and abroad.In this paper,the authors attribute this outstanding performance to three traditional factors and six modern factors.The traditional factors are high parental expectations,belief in the power of effort,and the mechanisms of personnel selection.The modern factors are the openness of Chinese education,curriculum and teaching reform,teacher training,improvement of comparatively poor schools,the financial resources allocation mechanism in compulsory education,and the reform of high school enrollment.展开更多
文摘Saponins extracted from Panax notoginseng are neuroprotective, but the mechanisms underlying this effect remain unclear. In the present study, we established a rat model of thoracic（T10） spinal cord transection, and injected Panax notoginseng saponins（100 mg/kg） or saline 30 minutes after injury. Locomotor functions were assessed using the Basso, Beattie, and Bresnahan（BBB） scale from 1 to 30 days after injury, and immunohistochemistry was carried out in the ventral horn of the spinal cord at 1 and 7 days to determine expression of nerve growth factor（NGF） and brain-derived neurotrophic factor（BDNF）. Our results show that at 7–30 days post injury, the BBB score was higher in rats treated with Panax notoginseng saponins than in those that received saline. Furthermore, at 7 days, more NGF- and BDNF-immunoreactive neurons were observed in the ventral horn of the spinal cord of rats that had received Panax notoginseng saponins than in those that received saline. These results indicate that Panax notoginseng saponins caused an upregulation of NGF and BDNF in rats with spinal cord transection, and improved hindlimb motor function.
基金This article is based on the phase achievement of national !"9th-Five-Year Plan" key project 96-013-01-01
文摘Chinese agriculture is undergoing a transformation process from traditional agriculture into modern agricultrue.This article discusses how land. labor, fertilizer, machinery etc. are used in agricultural production of different regions. reveals the influence of natural conditions and economic level on the utilization of modern agricultural factors. It proposes a system of allocation hoes of regional agricultural productive factors and points out the development stage and tendency of allocation of agricultural productive factors in different regions.
文摘The outstanding performance of Shanghai students in the 4th Programme for International Student Assessment(PISA 2009)gained widespread attention at home and abroad.In this paper,the authors attribute this outstanding performance to three traditional factors and six modern factors.The traditional factors are high parental expectations,belief in the power of effort,and the mechanisms of personnel selection.The modern factors are the openness of Chinese education,curriculum and teaching reform,teacher training,improvement of comparatively poor schools,the financial resources allocation mechanism in compulsory education,and the reform of high school enrollment.
